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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:3-methyl-2-oxobutanoic acid
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Accession:CHEBI:16530 term browser browse the term
Definition:A 2-oxo monocarboxylic acid that is the 2-oxo derivative of isovaleric acid.
Synonyms:related_synonym: 2-Keto-3-methylbutyric acid;   2-Ketoisovaleric acid;   2-Ketovaline;   2-Oxo-3-methylbutanoic acid;   2-Oxo-3-methylbutyric acid;   2-Oxoisovaleric acid;   3-Methyl-2-oxobutanoate;   3-Methyl-2-oxobutyric acid;   Dimethylpyruvic acid;   Formula=C5H8O3;   InChI=1S/C5H8O3/c1-3(2)4(6)5(7)8/h3H,1-2H3,(H,7,8);   InChIKey=QHKABHOOEWYVLI-UHFFFAOYSA-N;   Isopropylglyoxylic acid;   SMILES=CC(C)C(=O)C(O)=O;   alpha-Ketovaline;   alpha-keto-isovaleric acid;   alpha-oxo-beta-methylbutyricacid;   alpha-oxoisovaleric acid
 alt_id: CHEBI:1584;   CHEBI:20115;   CHEBI:43714
 xref: CAS:759-05-7;   DrugBank:DB04074;   HMDB:HMDB0000019;   KEGG:C00141;   KNApSAcK:C00007623;   LIPID_MAPS_instance:LMFA01020274
 xref_mesh: MESH:C001505
 xref: MetaCyc:2-KETO-ISOVALERATE;   PDBeChem:KIV;   PMID:17190852;   PMID:192504;   PMID:7021997;   Reaxys:1744951
 cyclic_relationship: is_conjugate_acid_of CHEBI:11851;   is_tautomer_of CHEBI:132177


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3-methyl-2-oxobutanoic acid term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G LEPR leptin receptor affects abundance ISO LEPR affects the abundance of alpha-ketoisovalerate CTD PMID:20567778 NCBI chr 1:65,420,652...65,641,559
Ensembl chr 1:65,420,652...65,641,559 		JBrowse link
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  CHEBI ontology 26034
    role 25961
      biological role 25929
        biochemical role 25162
          metabolite 25092
            eukaryotic metabolite 24514
              fungal metabolite 20891
                Saccharomyces cerevisiae metabolite 19480
                  3-methyl-2-oxobutanoic acid 1
Path 2
Term Annotations click to browse term
  CHEBI ontology 26034
    subatomic particle 26009
      composite particle 26009
        hadron 26020
          baryon 26009
            nucleon 26009
              atomic nucleus 26009
                atom 26009
                  main group element atom 25834
                    p-block element atom 25834
                      carbon group element atom 25434
                        carbon atom 25403
                          organic molecular entity 25392
                            heteroorganic entity 24766
                              organochalcogen compound 24378
                                organooxygen compound 24054
                                  carbon oxoacid 22749
                                    carboxylic acid 22729
                                      monocarboxylic acid 21724
                                        fatty acid 18997
                                          short-chain fatty acid 17992
                                            fatty acid 4:0 8283
                                              butyric acid 6783
                                                3-methyl-2-oxobutanoic acid 1
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