Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   

CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:3-methyl-2-oxobutanoic acid
go back to main search page
Accession:CHEBI:16530 term browser browse the term
Definition:A 2-oxo monocarboxylic acid that is the 2-oxo derivative of isovaleric acid.
Synonyms:related_synonym: 2-Keto-3-methylbutyric acid;   2-Ketoisovaleric acid;   2-Ketovaline;   2-Oxo-3-methylbutanoic acid;   2-Oxo-3-methylbutyric acid;   2-Oxoisovaleric acid;   3-Methyl-2-oxobutanoate;   3-Methyl-2-oxobutyric acid;   Dimethylpyruvic acid;   Formula=C5H8O3;   InChI=1S/C5H8O3/c1-3(2)4(6)5(7)8/h3H,1-2H3,(H,7,8);   InChIKey=QHKABHOOEWYVLI-UHFFFAOYSA-N;   Isopropylglyoxylic acid;   SMILES=CC(C)C(=O)C(O)=O;   alpha-Ketovaline;   alpha-keto-isovaleric acid;   alpha-oxo-beta-methylbutyricacid;   alpha-oxoisovaleric acid
 alt_id: CHEBI:1584;   CHEBI:20115;   CHEBI:43714
 xref: CAS:759-05-7;   DrugBank:DB04074;   HMDB:HMDB0000019;   KEGG:C00141;   KNApSAcK:C00007623;   LIPID_MAPS_instance:LMFA01020274
 xref_mesh: MESH:C001505
 xref: MetaCyc:2-KETO-ISOVALERATE;   PDBeChem:KIV;   PMID:17190852;   PMID:192504;   PMID:7021997;   Reaxys:1744951
 cyclic_relationship: is_conjugate_acid_of CHEBI:11851;   is_tautomer_of CHEBI:132177



show annotations for term's descendants           Sort by:
 
3-methyl-2-oxobutanoic acid term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Lepr leptin receptor affects abundance ISO LEPR affects the abundance of alpha-ketoisovalerate CTD PMID:20567778 NCBI chr 5:116,294,409...116,477,904
Ensembl chr 5:116,289,823...116,475,908
JBrowse link
G Slco1a4 solute carrier organic anion transporter family, member 1a4 affects abundance ISO SLCO1A4 protein affects the abundance of alpha-ketoisovalerate CTD PMID:21561886 NCBI chr 4:174,710,004...174,764,810
Ensembl chr 4:174,710,004...175,254,573
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 20089
    role 20042
      biological role 20011
        biochemical role 19671
          metabolite 19631
            eukaryotic metabolite 19358
              fungal metabolite 17645
                Saccharomyces cerevisiae metabolite 16816
                  3-methyl-2-oxobutanoic acid 2
Path 2
Term Annotations click to browse term
  CHEBI ontology 20089
    subatomic particle 20058
      composite particle 20058
        hadron 20088
          baryon 20088
            nucleon 20088
              atomic nucleus 20088
                atom 20058
                  main group element atom 19960
                    p-block element atom 19990
                      carbon group element atom 19916
                        carbon atom 19909
                          organic molecular entity 19909
                            organic group 18988
                              organic divalent group 18950
                                organodiyl group 18974
                                  carbonyl group 18903
                                    carbonyl compound 18925
                                      carboxylic acid 18597
                                        monocarboxylic acid 17843
                                          fatty acid 16480
                                            short-chain fatty acid 15801
                                              fatty acid 4:0 7905
                                                butyric acid 6274
                                                  3-methyl-2-oxobutanoic acid 2
paths to the root