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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:carbon dioxide
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Accession:CHEBI:16526 term browser browse the term
Definition:A one-carbon compound with formula CO2 in which the carbon is attached to each oxygen atom by a double bond. A colourless, odourless gas under normal conditions, it is produced during respiration by all animals, fungi and microorganisms that depend directly or indirectly on living or decaying plants for food.
Synonyms:exact_synonym: dioxidocarbon;   methanedione
 related_synonym: CO2;   E 290;   E290;   Formula=CO2;   InChI=1S/CO2/c2-1-3;   InChIKey=CURLTUGMZLYLDI-UHFFFAOYSA-N;   R-744;   SMILES=O=C=O;   carbonic anhydride
 alt_id: CHEBI:13282;   CHEBI:13283;   CHEBI:13284;   CHEBI:13285;   CHEBI:23011;   CHEBI:3283;   CHEBI:48829
 xref: Beilstein:1900390;   CAS:124-38-9;   Drug_Central:4256;   Gmelin:989;   HMDB:HMDB0001967;   KEGG:C00011;   KEGG:D00004
 xref_mesh: MESH:D002245
 xref: MetaCyc:CARBON-DIOXIDE;   MolBase:752;   PDBeChem:CO2;   PMID:10826146;   PMID:11094503;   PMID:11584085;   PMID:11802652;   PMID:14639145;   PMID:15050588;   PMID:16591971;   PMID:16656478;   PMID:16659660;   PMID:17190796;   PMID:17448243;   PMID:17878298;   PMID:17884085;   PMID:19043767;   PMID:19259576;   PMID:19854893;   PMID:23384758;   PMID:23828359;   PMID:24258718;   PMID:8482095;   PMID:8818713;   PMID:8869828;   PMID:9611769;   PMID:9730350;   PPDB:119;   Reaxys:1900390;   UM-BBD_compID:c0131;   Wikipedia:Carbon_dioxide



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carbon dioxide term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bdnf brain-derived neurotrophic factor multiple interactions EXP [Oxygen deficiency co-treated with Carbon Dioxide] results in decreased expression of BDNF protein; ifenprodil inhibits the reaction [[Oxygen deficiency co-treated with Carbon Dioxide] results in decreased expression of BDNF protein]; Lovastatin inhibits the reaction [[Oxygen deficiency co-treated with Carbon Dioxide] results in decreased expression of BDNF protein] CTD PMID:24718106 NCBI chr 3:96,165,042...96,215,621
Ensembl chr 3:96,165,042...96,215,615
JBrowse link
G Calca calcitonin-related polypeptide alpha multiple interactions
increases secretion
EXP Carbon Dioxide inhibits the reaction [Capsaicin results in increased secretion of CALCA protein]; Carbon Dioxide inhibits the reaction [Potassium Chloride results in increased secretion of CALCA protein]; Carbon Dioxide inhibits the reaction [S-Nitroso-N-Acetylpenicillamine results in increased secretion of CALCA protein]
Carbon Dioxide results in increased secretion of CALCA protein
CTD PMID:18052948 NCBI chr 1:168,878,212...168,883,176
Ensembl chr 1:168,878,214...168,883,105
JBrowse link
G Camk2b calcium/calmodulin-dependent protein kinase II beta multiple interactions EXP [Oxygen deficiency co-treated with Carbon Dioxide] results in increased expression of CAMK2B protein; ifenprodil inhibits the reaction [[Oxygen deficiency co-treated with Carbon Dioxide] results in increased expression of CAMK2B protein]; Lovastatin inhibits the reaction [[Oxygen deficiency co-treated with Carbon Dioxide] results in increased expression of CAMK2B protein] CTD PMID:24718106 NCBI chr14:80,845,206...80,934,172
Ensembl chr14:80,845,238...80,933,994
JBrowse link
G Creb1 cAMP responsive element binding protein 1 multiple interactions EXP [Oxygen deficiency co-treated with Carbon Dioxide] results in decreased phosphorylation of CREB1 protein; ifenprodil inhibits the reaction [[Oxygen deficiency co-treated with Carbon Dioxide] results in decreased phosphorylation of CREB1 protein]; Lovastatin inhibits the reaction [[Oxygen deficiency co-treated with Carbon Dioxide] results in decreased phosphorylation of CREB1 protein] CTD PMID:24718106 NCBI chr 9:65,903,511...65,972,562
Ensembl chr 9:65,903,547...65,970,816
JBrowse link
G Crh corticotropin releasing hormone increases response to substance ISO CRH protein results in increased susceptibility to Carbon Dioxide CTD PMID:8957205 NCBI chr 2:102,143,055...102,144,919
Ensembl chr 2:102,143,055...102,144,919
JBrowse link
G Dlg3 discs large MAGUK scaffold protein 3 multiple interactions EXP [Oxygen deficiency co-treated with Carbon Dioxide] results in increased expression of DLG3 protein; ifenprodil inhibits the reaction [[Oxygen deficiency co-treated with Carbon Dioxide] results in increased expression of DLG3 protein]; Lovastatin inhibits the reaction [[Oxygen deficiency co-treated with Carbon Dioxide] results in increased expression of DLG3 protein] CTD PMID:24718106 NCBI chr  X:65,859,653...65,911,887
Ensembl chr  X:65,860,172...65,910,322
JBrowse link
G Grin2b glutamate ionotropic receptor NMDA type subunit 2B multiple interactions EXP [Oxygen deficiency co-treated with Carbon Dioxide] results in increased expression of GRIN2B protein; ifenprodil inhibits the reaction [[Oxygen deficiency co-treated with Carbon Dioxide] results in increased expression of GRIN2B protein]; Lovastatin inhibits the reaction [[Oxygen deficiency co-treated with Carbon Dioxide] results in increased expression of GRIN2B protein] CTD PMID:24718106 NCBI chr 4:168,580,824...169,044,110
Ensembl chr 4:168,599,546...169,042,279
JBrowse link
G Mapk1 mitogen activated protein kinase 1 multiple interactions EXP [Oxygen deficiency co-treated with Carbon Dioxide] results in decreased phosphorylation of MAPK1 protein; [Oxygen deficiency co-treated with Carbon Dioxide] results in increased expression of MAPK1 mRNA; [Oxygen deficiency co-treated with Carbon Dioxide] results in increased phosphorylation of MAPK1 protein; ifenprodil inhibits the reaction [[Oxygen deficiency co-treated with Carbon Dioxide] results in decreased phosphorylation of MAPK1 protein]; Lovastatin inhibits the reaction [[Oxygen deficiency co-treated with Carbon Dioxide] results in decreased phosphorylation of MAPK1 protein]; notoginsenoside R1 inhibits the reaction [[Oxygen deficiency co-treated with Carbon Dioxide] results in increased expression of MAPK1 mRNA]; notoginsenoside R1 inhibits the reaction [[Oxygen deficiency co-treated with Carbon Dioxide] results in increased phosphorylation of MAPK1 protein] CTD PMID:24718106 PMID:25004876 NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616
JBrowse link
G Mapk3 mitogen activated protein kinase 3 multiple interactions EXP [Oxygen deficiency co-treated with Carbon Dioxide] results in decreased phosphorylation of MAPK3 protein; [Oxygen deficiency co-treated with Carbon Dioxide] results in increased expression of MAPK3 mRNA; [Oxygen deficiency co-treated with Carbon Dioxide] results in increased phosphorylation of MAPK3 protein; ifenprodil inhibits the reaction [[Oxygen deficiency co-treated with Carbon Dioxide] results in decreased phosphorylation of MAPK3 protein]; Lovastatin inhibits the reaction [[Oxygen deficiency co-treated with Carbon Dioxide] results in decreased phosphorylation of MAPK3 protein]; notoginsenoside R1 inhibits the reaction [[Oxygen deficiency co-treated with Carbon Dioxide] results in increased expression of MAPK3 mRNA]; notoginsenoside R1 inhibits the reaction [[Oxygen deficiency co-treated with Carbon Dioxide] results in increased phosphorylation of MAPK3 protein] CTD PMID:24718106 PMID:25004876 NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863
JBrowse link
G Neil1 nei-like DNA glycosylase 1 affects abundance ISO NEIL1 affects the abundance of Carbon Dioxide CTD PMID:21285402 NCBI chr 8:57,550,142...57,556,884
Ensembl chr 8:57,550,147...57,556,258
JBrowse link
G Ngb neuroglobin affects binding ISO Carbon Dioxide binds to [Heme binds to NGB protein] CTD PMID:16684569 NCBI chr 6:106,744,378...106,749,830
Ensembl chr 6:106,744,378...106,749,830
JBrowse link
G Ppara peroxisome proliferator activated receptor alpha multiple interactions ISO PPARA protein promotes the reaction [[GW 7647 results in increased oxidation of Palmitic Acid] which results in increased abundance of Carbon Dioxide] CTD PMID:21324916 NCBI chr 7:116,832,405...116,900,878
Ensembl chr 7:116,832,756...116,895,346
JBrowse link
G Rapgef3 Rap guanine nucleotide exchange factor 3 multiple interactions ISO [RAPGEF3 protein affects the susceptibility to Dietary Fats] which affects the chemical synthesis of Carbon Dioxide CTD PMID:27381457 NCBI chr 7:128,875,772...128,898,203
Ensembl chr 7:128,875,773...128,898,521
JBrowse link
G Slc9a1 solute carrier family 9 member A1 affects response to substance EXP SLC9A1 protein affects the susceptibility to Carbon Dioxide CTD PMID:16831598 NCBI chr 5:145,576,341...145,629,630
Ensembl chr 5:145,576,334...145,629,624
JBrowse link
G Sod1 superoxide dismutase 1 multiple interactions ISO [[[Bicarbonates co-treated with Carbon Dioxide] promotes the reaction [SOD1 protein binds to peroxycarbonic acid]] which results in increased reduction of peroxycarbonic acid] which results in increased chemical synthesis of Carbonates; [[Bicarbonates co-treated with Carbon Dioxide] promotes the reaction [SOD1 protein binds to peroxycarbonic acid]] which results in increased reduction of peroxycarbonic acid; [[SOD1 protein results in increased metabolism of Hydrogen Peroxide] results in increased oxidation of [Bicarbonates co-treated with Carbon Dioxide]] which results in increased chemical synthesis of Carbonates; [Bicarbonates co-treated with Carbon Dioxide] promotes the reaction [SOD1 protein binds to peroxycarbonic acid]; [Bicarbonates co-treated with Carbon Dioxide] promotes the reaction [SOD1 protein results in increased metabolism of Hydrogen Peroxide]; [SOD1 protein results in increased metabolism of Hydrogen Peroxide] results in increased oxidation of [Bicarbonates co-treated with Carbon Dioxide] CTD PMID:19243126 NCBI chr11:29,456,673...29,462,249
Ensembl chr11:29,456,558...29,462,249
JBrowse link
G Syngap1 synaptic Ras GTPase activating protein 1 multiple interactions EXP [Oxygen deficiency co-treated with Carbon Dioxide] results in increased expression of SYNGAP1 protein; ifenprodil inhibits the reaction [[Oxygen deficiency co-treated with Carbon Dioxide] results in increased expression of SYNGAP1 protein]; Lovastatin inhibits the reaction [[Oxygen deficiency co-treated with Carbon Dioxide] results in increased expression of SYNGAP1 protein] CTD PMID:24718106 NCBI chr20:5,026,366...5,056,659
Ensembl chr20:5,026,364...5,056,672
JBrowse link
G Tpi1 triosephosphate isomerase 1 increases expression EXP Carbon Dioxide results in increased expression of TPI1 mRNA CTD PMID:14762718 NCBI chr 4:157,615,283...157,618,813
Ensembl chr 4:157,615,386...157,619,541
JBrowse link
G Trh thyrotropin releasing hormone increases response to substance ISO TRH protein results in increased susceptibility to Carbon Dioxide CTD PMID:8957205 NCBI chr 4:124,742,111...124,777,094
Ensembl chr 4:124,742,111...124,744,637
JBrowse link
G Trpa1 transient receptor potential cation channel, subfamily A, member 1 increases activity EXP Carbon Dioxide results in increased activity of TRPA1 protein CTD PMID:20881114 NCBI chr 5:4,379,999...4,433,243
Ensembl chr 5:4,379,999...4,433,570
JBrowse link
G Trpv1 transient receptor potential cation channel, subfamily V, member 1 affects response to substance EXP TRPV1 protein affects the susceptibility to Carbon Dioxide CTD PMID:16831598 NCBI chr10:57,851,428...57,876,513
Ensembl chr10:57,851,428...57,876,513
JBrowse link

Term paths to the root
Path 1
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  CHEBI ontology 20059
    role 20009
      application 19747
        solvent 16665
          carbon dioxide 20
Path 2
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  CHEBI ontology 20059
    subatomic particle 20056
      composite particle 20056
        hadron 20056
          baryon 20056
            nucleon 20056
              atomic nucleus 20056
                atom 20056
                  main group element atom 19956
                    p-block element atom 19956
                      carbon group element atom 19882
                        carbon atom 19873
                          organic molecular entity 19873
                            heteroorganic entity 19555
                              organochalcogen compound 19293
                                organooxygen compound 19239
                                  carbon oxide 116
                                    carbon dioxide 20
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