CHEBI ONTOLOGY - ANNOTATIONS
The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/ . The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/ ). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term: formamide
Accession: CHEBI:16397
browse the term
Definition: The simplest monocarboxylic acid amide, obtained by formal condensation of formic acid with ammonia. The parent of the class of formaldehydes.
Synonyms: related_synonym: Ameisensaeureamid; Formamid; Formula=CH3NO; InChI=1S/CH3NO/c2-1-3/h1H,(H2,2,3); InChIKey=ZHNUHDYFZUAESO-UHFFFAOYSA-N; Methanamid; Methanamide; SMILES=[H]C(N)=O; carbamaldehyde; formimidic acid
alt_id: CHEBI:14275; CHEBI:24078; CHEBI:40895; CHEBI:5143
xref: Beilstein:505995; CAS:75-12-7; Gmelin:824; HMDB:HMDB0001536; KEGG:C00488
xref_mesh: MESH:C031066
xref: MetaCyc:FORMAMIDE; PDBeChem:ARF; PMID:11282235; PMID:11545392; PMID:12115814; PMID:14750843; PMID:15082074; PMID:17184725; PMID:19334838; PMID:21215846; PMID:21229996; PMID:21573300; PMID:21647491; PMID:21647492; PMID:21769603; PMID:21932847; Reaxys:505995; UM-BBD_compID:c0796; Wikipedia:Formamide
cyclic_relationship: is_tautomer_of CHEBI:48431
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Slc14a1
solute carrier family 14 member 1 (Kidd blood group)
affects transport
ISO
SLC14A1 protein affects the transport of formamide
CTD
PMID:17506977
NCBI chr18:71,565,453...71,608,807
Ensembl chr18:71,565,454...71,595,146
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Abcb1b
ATP-binding cassette, subfamily B (MDR/TAP), member 1B
decreases expression
EXP
Dimethylformamide results in decreased expression of ABCB1B mRNA
CTD
PMID:12883083
NCBI chr 4:25,242,761...25,325,194
Ensembl chr 4:25,242,798...25,325,199
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Bax
BCL2 associated X, apoptosis regulator
multiple interactions increases expression
ISO
Thiocarbamates analog inhibits the reaction [Dimethylformamide results in increased expression of BAX protein]
CTD
PMID:29984871
NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368
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Bcl2l1
Bcl2-like 1
multiple interactions increases expression
EXP ISO
[Dimethylformamide co-treated with Carbon Tetrachloride] results in decreased expression of BCL2L1 protein Dimethylformamide results in increased expression of BCL2L1 protein Thiocarbamates analog inhibits the reaction [Dimethylformamide results in decreased expression of BCL2L1 protein]
CTD
PMID:20097184 PMID:29984871
NCBI chr 3:141,253,508...141,304,582
Ensembl chr 3:141,253,523...141,303,479
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Casp3
caspase 3
multiple interactions increases expression
EXP ISO
[Dimethylformamide co-treated with Carbon Tetrachloride] results in increased activity of CASP3 protein Dimethylformamide results in increased expression of CASP3 protein modified form CAT protein inhibits the reaction [Dimethylformamide results in increased expression of CASP3 protein modified form]; Thiocarbamates analog inhibits the reaction [Dimethylformamide results in increased expression of CASP3 protein modified form]
CTD
PMID:20097184 PMID:29984871
NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648
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Casp9
caspase 9
multiple interactions increases expression
ISO
CAT protein inhibits the reaction [Dimethylformamide results in increased expression of CASP9 protein modified form]; Thiocarbamates analog inhibits the reaction [Dimethylformamide results in increased expression of CASP9 protein modified form]
CTD
PMID:29984871
NCBI chr 5:154,108,872...154,126,628
Ensembl chr 5:154,109,046...154,126,626
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Cat
catalase
multiple interactions
ISO
CAT protein inhibits the reaction [Dimethylformamide results in increased expression of CASP3 protein modified form]; CAT protein inhibits the reaction [Dimethylformamide results in increased expression of CASP9 protein modified form]; CAT protein inhibits the reaction [Dimethylformamide results in increased expression of TP53 protein]
CTD
PMID:29984871
NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478
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Cyp2e1
cytochrome P450, family 2, subfamily e, polypeptide 1
affects metabolic processing increases response to substance increases abundance multiple interactions increases expression increases oxidation increases metabolic processing
ISO EXP
CYP2E1 protein polymorphism affects the metabolism of Dimethylformamide CYP2E1 protein results in increased susceptibility to Dimethylformamide CYP2E1 polymorphism results in increased abundance of Dimethylformamide metabolite CYP2E1 protein affects the reaction [Dimethylformamide results in increased activity of GPT protein]; CYP2E1 protein affects the reaction [Dimethylformamide results in increased expression of HSP90B1 protein] Dimethylformamide results in increased expression of CYP2E1 protein CYP2E1 protein results in increased oxidation of Dimethylformamide CYP2E1 protein affects the metabolism of Dimethylformamide CYP2E1 protein results in increased metabolism of Dimethylformamide
CTD
PMID:9817075 PMID:10207612 PMID:11305777 PMID:15772367 PMID:29984871 PMID:31501917 More...
NCBI chr 1:195,840,330...195,850,728
Ensembl chr 1:195,840,058...195,864,023
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Ddit3
DNA-damage inducible transcript 3
multiple interactions
EXP
[Dimethylformamide co-treated with Carbon Tetrachloride] results in increased expression of DDIT3 mRNA
CTD
PMID:20097184
NCBI chr 7:63,115,645...63,121,203
Ensembl chr 7:63,116,380...63,121,201
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Eif2ak3
eukaryotic translation initiation factor 2 alpha kinase 3
multiple interactions
EXP
[Dimethylformamide co-treated with Carbon Tetrachloride] results in increased expression of EIF2AK3 protein modified form
CTD
PMID:20097184
NCBI chr 4:102,805,495...102,866,914
Ensembl chr 4:102,805,510...102,866,911
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Gpt
glutamic--pyruvic transaminase
multiple interactions increases activity
ISO
CYP2E1 protein affects the reaction [Dimethylformamide results in increased activity of GPT protein]
CTD
PMID:31501917
NCBI chr 7:108,416,646...108,419,495
Ensembl chr 7:108,416,642...108,419,494
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Gsr
glutathione-disulfide reductase
decreases expression
EXP
Dimethylformamide results in decreased expression of GSR mRNA
CTD
PMID:12883083
NCBI chr16:58,482,209...58,525,256
Ensembl chr16:58,482,505...58,525,661
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H2ax
H2A.X variant histone
increases expression
ISO
Dimethylformamide results in increased expression of H2AX protein
CTD
PMID:26387567
NCBI chr 8:44,671,927...44,673,257
Ensembl chr 8:44,671,786...44,673,239
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Hsp90b1
heat shock protein 90 beta family member 1
multiple interactions increases expression
EXP ISO
[Dimethylformamide co-treated with Carbon Tetrachloride] results in increased expression of HSP90B1 protein Dimethylformamide results in increased expression of HSP90B1 protein CYP2E1 protein affects the reaction [Dimethylformamide results in increased expression of HSP90B1 protein]
CTD
PMID:20097184 PMID:31501917
NCBI chr 7:21,110,431...21,124,762
Ensembl chr 7:21,110,457...21,124,788
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Hspa5
heat shock protein family A (Hsp70) member 5
multiple interactions
EXP
[Dimethylformamide co-treated with Carbon Tetrachloride] results in increased expression of HSPA5 mRNA; [Dimethylformamide co-treated with Carbon Tetrachloride] results in increased expression of HSPA5 protein
CTD
PMID:20097184
NCBI chr 3:18,055,507...18,059,969
Ensembl chr 3:18,055,405...18,059,891
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Ltf
lactotransferrin
increases expression
ISO
Dimethylformamide results in increased expression of LTF mRNA
CTD
PMID:18063697
NCBI chr 8:110,999,948...111,022,795
Ensembl chr 8:110,999,948...111,022,795
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Mpo
myeloperoxidase
increases expression
ISO
Dimethylformamide results in increased expression of MPO mRNA
CTD
PMID:18063697
NCBI chr10:72,594,458...72,608,862
Ensembl chr10:72,594,661...72,604,819
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Mre11
MRE11 homolog, double strand break repair nuclease
increases expression
ISO
Dimethylformamide results in increased expression of MRE11 mRNA; Dimethylformamide results in increased expression of MRE11 protein
CTD
PMID:26387567
NCBI chr 8:11,618,876...11,680,451
Ensembl chr 8:11,632,354...11,678,279
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Ncf1
neutrophil cytosolic factor 1
increases expression
ISO
Dimethylformamide results in increased expression of NCF1 mRNA
CTD
PMID:18063697
NCBI chr12:22,485,382...22,494,647
Ensembl chr12:22,485,451...22,494,646
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Nefh
neurofilament heavy chain
affects expression
EXP
Dimethylformamide affects the expression of NEFH mRNA
CTD
PMID:22954530
NCBI chr14:79,830,362...79,840,347
Ensembl chr14:79,830,362...79,840,351
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Parp1
poly (ADP-ribose) polymerase 1
multiple interactions
EXP
[Dimethylformamide co-treated with Carbon Tetrachloride] results in increased cleavage of PARP1 protein
CTD
PMID:20097184
NCBI chr13:92,307,593...92,339,406
Ensembl chr13:92,307,586...92,339,404
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Rad50
RAD50 double strand break repair protein
increases expression
ISO
Dimethylformamide results in increased expression of RAD50 mRNA; Dimethylformamide results in increased expression of RAD50 protein
CTD
PMID:26387567
NCBI chr10:37,809,353...37,861,309
Ensembl chr10:37,808,726...37,861,396
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Rad51
RAD51 recombinase
increases expression
ISO
Dimethylformamide results in increased expression of RAD51 mRNA; Dimethylformamide results in increased expression of RAD51 protein
CTD
PMID:26387567
NCBI chr 3:106,099,753...106,125,038
Ensembl chr 3:106,100,381...106,125,035
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Sult1a1
sulfotransferase family 1A member 1
multiple interactions
ISO
Dimethylformamide inhibits the reaction [SULT1A1 protein results in increased sulfation of 1-hydroxypyrene]; Dimethylformamide inhibits the reaction [SULT1A1 protein results in increased sulfation of 4-nitrophenol]
CTD
PMID:14570759
NCBI chr 1:181,272,022...181,276,750
Ensembl chr 1:181,272,023...181,275,562
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Sult2a1
sulfotransferase family 2A member 1
multiple interactions
ISO
Dimethylformamide inhibits the reaction [SULT2A1 protein results in increased sulfation of 1-hydroxypyrene]
CTD
PMID:14570759
NCBI chr 1:75,451,178...75,508,142
Ensembl chr 1:74,911,100...75,508,134
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Tnfsf10
TNF superfamily member 10
increases expression
ISO
Dimethylformamide results in increased expression of TNFSF10 mRNA; Dimethylformamide results in increased expression of TNFSF10 protein
CTD
PMID:18063697
NCBI chr 2:110,199,835...110,227,239
Ensembl chr 2:110,207,916...110,225,135
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Tp53
tumor protein p53
multiple interactions increases expression
ISO
CAT protein inhibits the reaction [Dimethylformamide results in increased expression of TP53 protein]; Thiocarbamates analog inhibits the reaction [Dimethylformamide results in increased expression of TP53 protein] Dimethylformamide results in increased expression of TP53 protein modified form
CTD
PMID:29984871
NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524
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Xrcc2
X-ray repair cross complementing 2
increases expression affects expression
ISO
Dimethylformamide results in increased expression of XRCC2 protein Dimethylformamide affects the expression of XRCC2 mRNA
CTD
PMID:26387567
NCBI chr 4:9,423,873...9,502,980
Ensembl chr 4:9,423,898...9,442,482
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Xrcc3
X-ray repair cross complementing 3
increases expression
ISO
Dimethylformamide results in increased expression of XRCC3 mRNA; Dimethylformamide results in increased expression of XRCC3 protein
CTD
PMID:26387567
NCBI chr 6:130,863,405...130,873,765
Ensembl chr 6:130,863,959...130,872,444
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Adamts7
ADAM metallopeptidase with thrombospondin type 1 motif, 7
affects expression
ISO
methylformamide affects the expression of ADAMTS7 mRNA; methylformamide analog affects the expression of ADAMTS7 mRNA
CTD
PMID:17040096
NCBI chr 8:90,704,727...90,744,331
Ensembl chr 8:90,704,727...90,744,328
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Ampd2
adenosine monophosphate deaminase 2
decreases expression
ISO
methylformamide analog results in decreased expression of AMPD2 mRNA; methylformamide results in decreased expression of AMPD2 mRNA
CTD
PMID:17040096
NCBI chr 2:195,707,609...195,720,454
Ensembl chr 2:195,707,610...195,720,271
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Angptl4
angiopoietin-like 4
increases expression
ISO
methylformamide analog results in increased expression of ANGPTL4 mRNA; methylformamide results in increased expression of ANGPTL4 mRNA
CTD
PMID:17040096
NCBI chr 7:14,550,288...14,557,797
Ensembl chr 7:14,550,311...14,556,519
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Ankrd10
ankyrin repeat domain 10
decreases expression
ISO
methylformamide analog results in decreased expression of ANKRD10 mRNA; methylformamide results in decreased expression of ANKRD10 mRNA
CTD
PMID:17040096
NCBI chr16:77,866,489...77,889,745
Ensembl chr16:77,864,261...77,889,745
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Anxa6
annexin A6
decreases expression
ISO
methylformamide analog results in decreased expression of ANXA6 mRNA; methylformamide results in decreased expression of ANXA6 mRNA
CTD
PMID:17040096
NCBI chr10:39,101,395...39,156,483
Ensembl chr10:39,097,109...39,156,433
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Aox1
aldehyde oxidase 1
increases expression
ISO
methylformamide analog results in increased expression of AOX1 mRNA; methylformamide results in increased expression of AOX1 mRNA
CTD
PMID:17040096
NCBI chr 9:59,579,621...59,658,772
Ensembl chr 9:59,579,649...59,658,770
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Arl4a
ADP-ribosylation factor like GTPase 4A
affects expression
ISO
methylformamide affects the expression of ARL4A mRNA; methylformamide analog affects the expression of ARL4A mRNA
CTD
PMID:17040096
NCBI chr 6:57,079,496...57,084,156
Ensembl chr 6:57,078,812...57,085,066
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B3galnt1
beta-1,3-N-acetylgalactosaminyltransferase 1 (globoside blood group)
decreases expression
ISO
methylformamide analog results in decreased expression of B3GALNT1 mRNA; methylformamide results in decreased expression of B3GALNT1 mRNA
CTD
PMID:17040096
NCBI chr 2:153,847,297...153,877,371
Ensembl chr 2:153,846,474...153,877,332
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Birc2
baculoviral IAP repeat-containing 2
decreases expression
ISO
methylformamide analog results in decreased expression of BIRC2 mRNA; methylformamide results in decreased expression of BIRC2 mRNA
CTD
PMID:17040096
NCBI chr 8:4,968,856...4,989,325
Ensembl chr 8:4,968,842...4,988,732
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Brd2
bromodomain containing 2
increases expression
ISO
methylformamide analog results in increased expression of BRD2 mRNA; methylformamide results in increased expression of BRD2 mRNA
CTD
PMID:17040096
NCBI chr20:4,727,078...4,735,389
Ensembl chr20:4,728,151...4,735,388
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Cacybp
calcyclin binding protein
increases expression
ISO
methylformamide analog results in increased expression of CACYBP mRNA; methylformamide results in increased expression of CACYBP mRNA
CTD
PMID:17040096
NCBI chr13:72,437,485...72,447,810
Ensembl chr13:72,437,490...72,450,177
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Cavin2
caveolae associated protein 2
decreases expression
ISO
methylformamide analog results in decreased expression of CAVIN2 mRNA; methylformamide results in decreased expression of CAVIN2 mRNA
CTD
PMID:17040096
NCBI chr 9:50,302,079...50,314,096
Ensembl chr 9:50,301,206...50,314,147
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Ccl3
C-C motif chemokine ligand 3
increases expression
ISO
methylformamide analog results in increased expression of CCL3 mRNA; methylformamide results in increased expression of CCL3 mRNA
CTD
PMID:17040096
NCBI chr10:68,451,388...68,452,938
Ensembl chr10:68,451,388...68,452,938
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Ccn2
cellular communication network factor 2
increases expression
ISO
methylformamide analog results in increased expression of CCN2 mRNA; methylformamide results in increased expression of CCN2 mRNA
CTD
PMID:17040096
NCBI chr 1:20,802,199...20,805,315
Ensembl chr 1:20,802,199...20,805,734
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Ccnd1
cyclin D1
decreases expression
ISO
methylformamide analog results in decreased expression of CCND1 mRNA; methylformamide results in decreased expression of CCND1 mRNA
CTD
PMID:17040096
NCBI chr 1:200,089,002...200,098,524
Ensembl chr 1:200,089,002...200,098,602
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Ccnd2
cyclin D2
decreases expression
ISO
methylformamide analog results in decreased expression of CCND2 mRNA; methylformamide results in decreased expression of CCND2 mRNA
CTD
PMID:17040096
NCBI chr 4:159,966,883...159,989,261
Ensembl chr 4:159,962,363...159,989,495
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Cdc45
cell division cycle 45
increases expression
ISO
methylformamide analog results in increased expression of CDC45 mRNA; methylformamide results in increased expression of CDC45 mRNA
CTD
PMID:17040096
NCBI chr11:82,185,427...82,210,630
Ensembl chr11:82,185,473...82,210,619
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Cish
cytokine inducible SH2-containing protein
decreases expression
ISO
methylformamide analog results in decreased expression of CISH mRNA; methylformamide results in decreased expression of CISH mRNA
CTD
PMID:17040096
NCBI chr 8:107,972,306...107,977,254
Ensembl chr 8:107,972,306...107,977,250
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Clstn2
calsyntenin 2
increases expression
ISO
methylformamide analog results in increased expression of CLSTN2 mRNA; methylformamide results in increased expression of CLSTN2 mRNA
CTD
PMID:17040096
NCBI chr 8:98,020,406...98,637,232
Ensembl chr 8:98,021,666...98,637,731
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Csnk1d
casein kinase 1, delta
affects expression
ISO
methylformamide affects the expression of CSNK1D mRNA; methylformamide analog affects the expression of CSNK1D mRNA
CTD
PMID:17040096
NCBI chr10:106,221,992...106,256,620
Ensembl chr10:106,221,992...106,256,614
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Cxadr
CXADR, Ig-like cell adhesion molecule
affects expression
ISO
methylformamide affects the expression of CXADR mRNA; methylformamide analog affects the expression of CXADR mRNA
CTD
PMID:17040096
NCBI chr11:16,982,752...17,030,078
Ensembl chr11:16,982,860...17,030,046
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Cyp2e1
cytochrome P450, family 2, subfamily e, polypeptide 1
increases metabolic processing multiple interactions
ISO EXP
CYP2E1 protein results in increased metabolism of methylformamide 4-nitrophenol inhibits the reaction [CYP2E1 protein results in increased metabolism of methylformamide]; Dimethyl Sulfoxide inhibits the reaction [CYP2E1 protein results in increased metabolism of methylformamide]; Ditiocarb inhibits the reaction [CYP2E1 protein results in increased metabolism of methylformamide]; Fomepizole promotes the reaction [CYP2E1 protein results in increased metabolism of methylformamide]
CTD
PMID:1538706
NCBI chr 1:195,840,330...195,850,728
Ensembl chr 1:195,840,058...195,864,023
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Dnaja1
DnaJ heat shock protein family (Hsp40) member A1
increases expression
ISO
methylformamide analog results in increased expression of DNAJA1 mRNA; methylformamide results in increased expression of DNAJA1 mRNA
CTD
PMID:17040096
NCBI chr 5:55,842,414...55,853,326
Ensembl chr 5:55,842,426...55,853,967
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Dnmt3a
DNA methyltransferase 3 alpha
affects expression
ISO
methylformamide affects the expression of DNMT3A mRNA; methylformamide analog affects the expression of DNMT3A mRNA
CTD
PMID:17040096
NCBI chr 6:26,791,517...26,902,161
Ensembl chr 6:26,822,609...26,896,687
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Dusp10
dual specificity phosphatase 10
affects expression
ISO
methylformamide affects the expression of DUSP10 mRNA; methylformamide analog affects the expression of DUSP10 mRNA
CTD
PMID:17040096
NCBI chr13:95,613,716...95,651,716
Ensembl chr13:95,614,292...95,651,716
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Dusp6
dual specificity phosphatase 6
increases expression
ISO
methylformamide analog results in increased expression of DUSP6 mRNA; methylformamide results in increased expression of DUSP6 mRNA
CTD
PMID:17040096
NCBI chr 7:34,092,848...34,097,186
Ensembl chr 7:34,092,943...34,097,185
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Dusp7
dual specificity phosphatase 7
decreases expression
ISO
methylformamide analog results in decreased expression of DUSP7 mRNA; methylformamide results in decreased expression of DUSP7 mRNA
CTD
PMID:17040096
NCBI chr 8:107,009,369...107,016,404
Ensembl chr 8:107,008,528...107,016,404
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Egfr
epidermal growth factor receptor
decreases expression
ISO
methylformamide analog results in decreased expression of EGFR mRNA; methylformamide results in decreased expression of EGFR mRNA
CTD
PMID:17040096
NCBI chr14:91,176,931...91,349,722
Ensembl chr14:91,177,067...91,344,382
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Entpd5
ectonucleoside triphosphate diphosphohydrolase 5
affects expression
ISO
methylformamide affects the expression of ENTPD5 mRNA; methylformamide analog affects the expression of ENTPD5 mRNA
CTD
PMID:17040096
NCBI chr 6:104,019,095...104,055,311
Ensembl chr 6:104,019,185...104,055,530
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Fgf21
fibroblast growth factor 21
increases expression
ISO
methylformamide analog results in increased expression of FGF21 mRNA; methylformamide results in increased expression of FGF21 mRNA
CTD
PMID:17040096
NCBI chr 1:96,083,495...96,084,738
Ensembl chr 1:96,083,441...96,090,454
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Fn1
fibronectin 1
decreases expression
ISO
methylformamide analog results in decreased expression of FN1 mRNA; methylformamide results in decreased expression of FN1 mRNA
CTD
PMID:17040096
NCBI chr 9:73,196,044...73,264,695
Ensembl chr 9:73,196,044...73,264,678
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Fos
Fos proto-oncogene, AP-1 transcription factor subunit
increases expression
ISO
methylformamide analog results in increased expression of FOS mRNA; methylformamide results in increased expression of FOS mRNA
CTD
PMID:17040096
NCBI chr 6:105,121,170...105,124,036
Ensembl chr 6:105,121,170...105,124,036
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Gabarapl1
GABA type A receptor associated protein like 1
increases expression
ISO
methylformamide analog results in increased expression of GABARAPL1 mRNA; methylformamide results in increased expression of GABARAPL1 mRNA
CTD
PMID:17040096
NCBI chr 4:162,980,309...162,989,452
Ensembl chr 4:162,980,249...162,989,450
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Gas2
growth arrest-specific 2
decreases expression
ISO
methylformamide analog results in decreased expression of GAS2 mRNA; methylformamide results in decreased expression of GAS2 mRNA
CTD
PMID:17040096
NCBI chr 1:101,452,361...101,582,619
Ensembl chr 1:101,482,591...101,582,619
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Gclc
glutamate-cysteine ligase, catalytic subunit
affects expression
ISO
methylformamide affects the expression of GCLC mRNA; methylformamide analog affects the expression of GCLC mRNA
CTD
PMID:17040096
NCBI chr 8:78,629,899...78,668,547
Ensembl chr 8:78,630,127...78,668,544
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Gdf15
growth differentiation factor 15
increases expression
ISO
methylformamide analog results in increased expression of GDF15 mRNA; methylformamide results in increased expression of GDF15 mRNA
CTD
PMID:17040096
NCBI chr16:18,805,312...18,807,893
Ensembl chr16:18,805,239...18,808,055
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Gdf9
growth differentiation factor 9
increases expression
ISO
methylformamide analog results in increased expression of GDF9 mRNA; methylformamide results in increased expression of GDF9 mRNA
CTD
PMID:17040096
NCBI chr10:37,589,200...37,599,970
Ensembl chr10:37,595,679...37,599,672
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Grpel2
GrpE-like 2, mitochondrial
increases expression
ISO
methylformamide analog results in increased expression of GRPEL2 mRNA; methylformamide results in increased expression of GRPEL2 mRNA
CTD
PMID:17040096
NCBI chr18:55,167,831...55,180,073
Ensembl chr18:55,168,209...55,180,180
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Gsdme
gasdermin E
increases expression
ISO
methylformamide analog results in increased expression of GSDME mRNA; methylformamide results in increased expression of GSDME mRNA
CTD
PMID:17040096
NCBI chr 4:79,258,799...79,321,129
Ensembl chr 4:79,257,804...79,320,806
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Gsta3
glutathione S-transferase alpha 3
affects expression
ISO
methylformamide affects the expression of GSTA2 mRNA; methylformamide analog affects the expression of GSTA2 mRNA
CTD
PMID:17040096
NCBI chr 9:23,658,574...23,684,240
Ensembl chr 9:23,658,574...23,684,240
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Gtf2ird1
GTF2I repeat domain containing 1
affects expression
ISO
methylformamide affects the expression of GTF2IRD1 mRNA; methylformamide analog affects the expression of GTF2IRD1 mRNA
CTD
PMID:17040096
NCBI chr12:22,254,113...22,361,052
Ensembl chr12:22,254,221...22,361,040
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Gtpbp2
GTP binding protein 2
affects expression
ISO
methylformamide affects the expression of GTPBP2 mRNA; methylformamide analog affects the expression of GTPBP2 mRNA
CTD
PMID:17040096
NCBI chr 9:14,813,964...14,823,419
Ensembl chr 9:14,813,964...14,823,241
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Habp2
hyaluronan binding protein 2
increases expression
ISO
methylformamide analog results in increased expression of HABP2 mRNA; methylformamide results in increased expression of HABP2 mRNA
CTD
PMID:17040096
NCBI chr 1:255,315,870...255,350,161
Ensembl chr 1:255,315,915...255,350,160
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Hbp1
HMG-box transcription factor 1
increases expression
ISO
methylformamide analog results in increased expression of HBP1 mRNA; methylformamide results in increased expression of HBP1 mRNA
CTD
PMID:17040096
NCBI chr 6:48,529,633...48,555,775
Ensembl chr 6:48,529,372...48,555,787
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Hmgcr
3-hydroxy-3-methylglutaryl-CoA reductase
affects expression
ISO
methylformamide affects the expression of HMGCR mRNA; methylformamide analog affects the expression of HMGCR mRNA
CTD
PMID:17040096
NCBI chr 2:27,997,523...28,018,983
Ensembl chr 2:27,997,525...28,019,703
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Hmox1
heme oxygenase 1
affects expression
ISO
methylformamide affects the expression of HMOX1 mRNA; methylformamide analog affects the expression of HMOX1 mRNA
CTD
PMID:17040096
NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079
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Hnrnpa2b1
heterogeneous nuclear ribonucleoprotein A2/B1
decreases expression
ISO
methylformamide analog results in decreased expression of HNRNPA2B1 mRNA; methylformamide results in decreased expression of HNRNPA2B1 mRNA
CTD
PMID:17040096
NCBI chr 4:80,534,659...80,545,297
Ensembl chr 4:80,534,651...80,545,249
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Hspa1b
heat shock protein family A (Hsp70) member 1B
affects expression
ISO
methylformamide affects the expression of HSPA1B mRNA; methylformamide analog affects the expression of HSPA1B mRNA
CTD
PMID:17040096
NCBI chr20:3,855,104...3,859,148
Ensembl chr20:3,856,006...3,873,240
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Hspa8
heat shock protein family A (Hsp70) member 8
increases expression
ISO
methylformamide analog results in increased expression of HSPA8 mRNA; methylformamide results in increased expression of HSPA8 mRNA
CTD
PMID:17040096
NCBI chr 8:41,183,397...41,187,260
Ensembl chr 8:41,183,264...41,187,259
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Hspb1
heat shock protein family B (small) member 1
affects expression
ISO
methylformamide affects the expression of HSPB1 mRNA; methylformamide analog affects the expression of HSPB1 mRNA
CTD
PMID:17040096
NCBI chr12:20,794,014...20,795,675
Ensembl chr12:20,794,028...20,795,743
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Hspb8
heat shock protein family B (small) member 8
affects expression
ISO
methylformamide affects the expression of HSPB8 mRNA; methylformamide analog affects the expression of HSPB8 mRNA
CTD
PMID:17040096
NCBI chr12:40,176,405...40,205,002
Ensembl chr12:40,176,532...40,191,185
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Hspd1
heat shock protein family D (Hsp60) member 1
increases expression
ISO
methylformamide analog results in increased expression of HSPD1 mRNA; methylformamide results in increased expression of HSPD1 mRNA
CTD
PMID:17040096
NCBI chr 9:56,579,195...56,590,011
Ensembl chr 9:56,579,201...56,589,662
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Hsph1
heat shock protein family H (Hsp110) member 1
increases expression
ISO
methylformamide analog results in increased expression of HSPH1 mRNA; methylformamide results in increased expression of HSPH1 mRNA
CTD
PMID:17040096
NCBI chr12:5,390,916...5,410,224
Ensembl chr12:5,390,922...5,410,224
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Ikbkg
inhibitor of nuclear factor kappa B kinase regulatory subunit gamma
affects expression
ISO
methylformamide affects the expression of IKBKG mRNA; methylformamide analog affects the expression of IKBKG mRNA
CTD
PMID:17040096
NCBI chr X:152,216,485...152,241,476
Ensembl chr X:152,216,596...152,239,499
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Il15ra
interleukin 15 receptor subunit alpha
decreases expression
ISO
methylformamide analog results in decreased expression of IL15RA mRNA; methylformamide results in decreased expression of IL15RA mRNA
CTD
PMID:17040096
NCBI chr17:66,802,300...66,831,973
Ensembl chr17:66,802,334...66,832,278
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Il1rap
interleukin 1 receptor accessory protein
decreases expression
ISO
methylformamide analog results in decreased expression of IL1RAP mRNA; methylformamide results in decreased expression of IL1RAP mRNA
CTD
PMID:17040096
NCBI chr11:74,062,999...74,199,530
Ensembl chr11:74,070,304...74,199,530
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Inpp1
inositol polyphosphate-1-phosphatase
decreases expression
ISO
methylformamide analog results in decreased expression of INPP1 mRNA; methylformamide results in decreased expression of INPP1 mRNA
CTD
PMID:17040096
NCBI chr 9:48,688,037...48,717,793
Ensembl chr 9:48,669,901...48,717,793
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Kcnk5
potassium two pore domain channel subfamily K member 5
decreases expression
ISO
methylformamide analog results in decreased expression of KCNK5 mRNA; methylformamide results in decreased expression of KCNK5 mRNA
CTD
PMID:17040096
NCBI chr15:4,122,442...4,164,718
Ensembl chr15:4,122,442...4,164,718
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Kdm2b
lysine demethylase 2B
decreases expression
ISO
methylformamide analog results in decreased expression of KDM2B mRNA; methylformamide results in decreased expression of KDM2B mRNA
CTD
PMID:17040096
NCBI chr12:33,566,530...33,701,366
Ensembl chr12:33,574,657...33,701,355
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Klf6
Kruppel-like factor 6
affects expression
ISO
methylformamide affects the expression of KLF6 mRNA; methylformamide analog affects the expression of KLF6 mRNA
CTD
PMID:17040096
NCBI chr17:64,539,456...64,548,451
Ensembl chr17:64,531,463...64,588,570
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Lgals7
galectin 7
affects expression
ISO
methylformamide affects the expression of LGALS7 mRNA; methylformamide analog affects the expression of LGALS7 mRNA
CTD
PMID:17040096
NCBI chr 1:84,148,612...84,152,016
Ensembl chr 1:84,150,252...84,152,015
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Lipg
lipase G, endothelial type
decreases expression
ISO
methylformamide analog results in decreased expression of LIPG mRNA; methylformamide results in decreased expression of LIPG mRNA
CTD
PMID:17040096
NCBI chr18:68,514,923...68,536,105
Ensembl chr18:68,514,923...68,536,260
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Lpin2
lipin 2
increases expression
ISO
methylformamide analog results in increased expression of LPIN2 mRNA; methylformamide results in increased expression of LPIN2 mRNA
CTD
PMID:17040096
NCBI chr 9:111,083,378...111,158,193
Ensembl chr 9:111,083,745...111,158,193
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Ly96
lymphocyte antigen 96
affects expression
ISO
methylformamide affects the expression of LY96 mRNA; methylformamide analog affects the expression of LY96 mRNA
CTD
PMID:17040096
NCBI chr 5:2,582,233...2,612,357
Ensembl chr 5:2,582,254...2,612,386
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Mafk
MAF bZIP transcription factor K
affects expression
ISO
methylformamide affects the expression of MAFK mRNA; methylformamide analog affects the expression of MAFK mRNA
CTD
PMID:17040096
NCBI chr12:14,834,628...14,856,414
Ensembl chr12:14,833,984...14,837,048 Ensembl chr12:14,833,984...14,837,048
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Nde1
nudE neurodevelopment protein 1
decreases expression
ISO
methylformamide analog results in decreased expression of NDE1 mRNA; methylformamide results in decreased expression of NDE1 mRNA
CTD
PMID:17040096
NCBI chr10:839,788...883,946
Ensembl chr10:839,788...883,869
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Noct
nocturnin
decreases expression
ISO
methylformamide analog results in decreased expression of NOCT mRNA; methylformamide results in decreased expression of NOCT mRNA
CTD
PMID:17040096
NCBI chr 2:135,271,189...135,291,407
Ensembl chr 2:135,271,189...135,291,400
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Nr1d2
nuclear receptor subfamily 1, group D, member 2
increases expression
ISO
methylformamide analog results in increased expression of NR1D2 mRNA; methylformamide results in increased expression of NR1D2 mRNA
CTD
PMID:17040096
NCBI chr15:7,524,257...7,550,553
Ensembl chr15:7,524,257...7,550,553
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Pgd
phosphogluconate dehydrogenase
affects expression
ISO
methylformamide affects the expression of PGD mRNA; methylformamide analog affects the expression of PGD mRNA
CTD
PMID:17040096
NCBI chr 5:159,582,746...159,598,945
Ensembl chr 5:159,561,271...159,742,778
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Plk3
polo-like kinase 3
increases expression
ISO
methylformamide analog results in increased expression of PLK3 mRNA; methylformamide results in increased expression of PLK3 mRNA
CTD
PMID:17040096
NCBI chr 5:130,607,142...130,612,317
Ensembl chr 5:130,607,142...130,612,317
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Pnrc1
proline-rich nuclear receptor coactivator 1
affects expression
ISO
methylformamide affects the expression of PNRC1 mRNA; methylformamide analog affects the expression of PNRC1 mRNA
CTD
PMID:17040096
NCBI chr 5:47,647,070...47,657,832
Ensembl chr 5:47,647,071...47,650,161
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Ppp1r10
protein phosphatase 1, regulatory subunit 10
increases expression
ISO
methylformamide analog results in increased expression of PPP1R10 mRNA; methylformamide results in increased expression of PPP1R10 mRNA
CTD
PMID:17040096
NCBI chr20:2,822,995...2,838,125
Ensembl chr20:2,822,995...2,837,611
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Rbpms
RNA binding protein, mRNA processing factor
affects expression
ISO
methylformamide affects the expression of RBPMS mRNA; methylformamide analog affects the expression of RBPMS mRNA
CTD
PMID:17040096
NCBI chr16:58,239,370...58,395,424
Ensembl chr16:58,239,474...58,395,426
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Rcan1
regulator of calcineurin 1
affects expression
ISO
methylformamide affects the expression of RCAN1 mRNA; methylformamide analog affects the expression of RCAN1 mRNA
CTD
PMID:17040096
NCBI chr11:31,622,208...31,702,150
Ensembl chr11:31,622,210...31,702,045
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RT1-DMb
RT1 class II, locus DMb
decreases expression
ISO
methylformamide analog results in decreased expression of H2-DMB2 mRNA; methylformamide results in decreased expression of H2-DMB2 mRNA
CTD
PMID:17040096
NCBI chr20:4,693,102...4,700,340
Ensembl chr20:4,693,103...4,700,340
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Rtp3
receptor (chemosensory) transporter protein 3
decreases expression
ISO
methylformamide analog results in decreased expression of RTP3 mRNA; methylformamide results in decreased expression of RTP3 mRNA
CTD
PMID:17040096
NCBI chr 8:110,970,154...110,975,000
Ensembl chr 8:110,970,160...110,974,699
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Sgk1
serum/glucocorticoid regulated kinase 1
increases expression
ISO
methylformamide analog results in increased expression of SGK1 mRNA; methylformamide results in increased expression of SGK1 mRNA
CTD
PMID:17040096
NCBI chr 1:22,980,257...23,098,122
Ensembl chr 1:22,980,261...23,098,283
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Sgk2
serum/glucocorticoid regulated kinase 2
increases expression
ISO
methylformamide analog results in increased expression of SGK2 mRNA; methylformamide results in increased expression of SGK2 mRNA
CTD
PMID:17040096
NCBI chr 3:151,644,102...151,669,480
Ensembl chr 3:151,644,102...151,669,480
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Sirt1
sirtuin 1
increases expression
ISO
methylformamide analog results in increased expression of SIRT1 mRNA; methylformamide results in increased expression of SIRT1 mRNA
CTD
PMID:17040096
NCBI chr20:25,307,143...25,329,260
Ensembl chr20:25,306,917...25,329,260
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Slc14a1
solute carrier family 14 member 1 (Kidd blood group)
multiple interactions affects transport
ISO
methylformamide inhibits the reaction [SLC14A1 protein affects the transport of Urea] SLC14A1 protein affects the transport of methylformamide
CTD
PMID:17506977
NCBI chr18:71,565,453...71,608,807
Ensembl chr18:71,565,454...71,595,146
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Slc25a19
solute carrier family 25 member 19
decreases expression
ISO
methylformamide analog results in decreased expression of SLC25A19 mRNA; methylformamide results in decreased expression of SLC25A19 mRNA
CTD
PMID:17040096
NCBI chr10:100,853,554...100,867,517
Ensembl chr10:100,847,168...100,867,447
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Slc38a2
solute carrier family 38, member 2
increases expression
ISO
methylformamide analog results in increased expression of SLC38A2 mRNA; methylformamide results in increased expression of SLC38A2 mRNA
CTD
PMID:17040096
NCBI chr 7:127,851,267...127,863,482
Ensembl chr 7:127,851,267...127,863,436
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Slc39a8
solute carrier family 39 member 8
increases expression
ISO
methylformamide analog results in increased expression of SLC39A8 mRNA; methylformamide results in increased expression of SLC39A8 mRNA
CTD
PMID:17040096
NCBI chr 2:224,171,787...224,319,326
Ensembl chr 2:224,256,654...224,319,129
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Sqstm1
sequestosome 1
affects expression
ISO
methylformamide affects the expression of SQSTM1 mRNA; methylformamide analog affects the expression of SQSTM1 mRNA
CTD
PMID:17040096
NCBI chr10:34,525,517...34,536,685
Ensembl chr10:34,525,519...34,536,673
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Srebf1
sterol regulatory element binding transcription factor 1
decreases expression
ISO
methylformamide analog results in decreased expression of SREBF1 mRNA; methylformamide results in decreased expression of SREBF1 mRNA
CTD
PMID:17040096
NCBI chr10:45,007,637...45,029,650
Ensembl chr10:45,007,637...45,029,650
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Srpk2
SRSF protein kinase 2
increases expression
ISO
methylformamide analog results in increased expression of SRPK2 mRNA; methylformamide results in increased expression of SRPK2 mRNA
CTD
PMID:17040096
NCBI chr 4:11,464,684...11,655,993
Ensembl chr 4:11,464,674...11,655,990
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Srxn1
sulfiredoxin 1
affects expression
ISO
methylformamide affects the expression of SRXN1 mRNA; methylformamide analog affects the expression of SRXN1 mRNA
CTD
PMID:17040096
NCBI chr 3:140,604,490...140,610,050
Ensembl chr 3:140,599,608...140,628,448
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Thrsp
thyroid hormone responsive
decreases expression
ISO
methylformamide analog results in decreased expression of THRSP mRNA; methylformamide results in decreased expression of THRSP mRNA
CTD
PMID:17040096
NCBI chr 1:151,723,415...151,727,740
Ensembl chr 1:151,723,086...151,728,075
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Tnfaip6
TNF alpha induced protein 6
affects expression
ISO
methylformamide affects the expression of TNFAIP6 mRNA; methylformamide analog affects the expression of TNFAIP6 mRNA
CTD
PMID:17040096
NCBI chr 3:36,502,250...36,521,652
Ensembl chr 3:36,502,188...36,521,649
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Tob1
transducer of ErbB-2.1
decreases expression
ISO
methylformamide analog results in decreased expression of TOB1 mRNA; methylformamide results in decreased expression of TOB1 mRNA
CTD
PMID:17040096
NCBI chr10:79,163,093...79,165,131
Ensembl chr10:79,160,154...79,165,215
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Topors
TOP1 binding arginine/serine rich protein, E3 ubiquitin ligase
increases expression
ISO
methylformamide analog results in increased expression of TOPORS mRNA; methylformamide results in increased expression of TOPORS mRNA
CTD
PMID:17040096
NCBI chr 5:55,388,033...55,399,937
Ensembl chr 5:55,387,632...55,399,937
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Trib3
tribbles pseudokinase 3
affects expression
ISO
methylformamide affects the expression of TRIB3 mRNA; methylformamide analog affects the expression of TRIB3 mRNA
CTD
PMID:17040096
NCBI chr 3:140,809,634...140,815,230
Ensembl chr 3:140,809,043...140,814,497
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Txnrd1
thioredoxin reductase 1
affects expression
ISO
methylformamide affects the expression of TXNRD1 mRNA; methylformamide analog affects the expression of TXNRD1 mRNA
CTD
PMID:17040096
NCBI chr 7:20,830,042...20,914,990
Ensembl chr 7:20,830,045...20,907,863
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Ubap1
ubiquitin-associated protein 1
affects expression
ISO
methylformamide affects the expression of UBAP1 mRNA; methylformamide analog affects the expression of UBAP1 mRNA
CTD
PMID:17040096
NCBI chr 5:56,520,722...56,561,153
Ensembl chr 5:56,520,743...56,561,152
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Ugdh
UDP-glucose 6-dehydrogenase
affects expression
ISO
methylformamide affects the expression of UGDH mRNA; methylformamide analog affects the expression of UGDH mRNA
CTD
PMID:17040096
NCBI chr14:42,848,704...42,872,351
Ensembl chr14:42,848,854...42,872,354
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Ugp2
UDP-glucose pyrophosphorylase 2
increases expression
ISO
methylformamide analog results in increased expression of UGP2 mRNA; methylformamide results in increased expression of UGP2 mRNA
CTD
PMID:17040096
NCBI chr14:95,456,330...95,497,483
Ensembl chr14:95,456,330...95,496,830
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Usp9x
ubiquitin specific peptidase 9, X-linked
increases expression
ISO
methylformamide analog results in increased expression of USP9X mRNA; methylformamide results in increased expression of USP9X mRNA
CTD
PMID:17040096
NCBI chr X:9,588,825...9,726,993
Ensembl chr X:9,588,825...9,696,711
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Vegfd
vascular endothelial growth factor D
increases expression
ISO
methylformamide analog results in increased expression of VEGFD mRNA; methylformamide results in increased expression of VEGFD mRNA
CTD
PMID:17040096
NCBI chr X:30,073,122...30,108,413
Ensembl chr X:30,074,163...30,108,295
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Zfp467
zinc finger protein 467
decreases expression
ISO
methylformamide analog results in decreased expression of ZFP467 mRNA; methylformamide results in decreased expression of ZFP467 mRNA
CTD
PMID:17040096
NCBI chr 4:77,385,752...77,394,709
Ensembl chr 4:77,385,758...77,392,229
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Zfx
zinc finger protein X-linked
increases expression
ISO
methylformamide analog results in increased expression of ZFX mRNA; methylformamide results in increased expression of ZFX mRNA
CTD
PMID:17040096
NCBI chr X:58,804,690...58,853,155
Ensembl chr X:58,804,691...58,853,265
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Zwint
ZW10 interacting kinetochore protein
affects expression
ISO
methylformamide affects the expression of ZWINT mRNA; methylformamide analog affects the expression of ZWINT mRNA
CTD
PMID:17040096
NCBI chr20:15,938,157...15,953,997
Ensembl chr20:15,938,157...15,953,957
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