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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:anthocyanidin cation
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Accession:CHEBI:16366 term browser browse the term
Definition:Any organic cation that is an aglycon of anthocyanin cation; they are oxygenated derivatives of flavylium (2-phenylchromenylium).
Synonyms:exact_synonym: anthocyanidins
 related_synonym: Anthocyanidin;   Formula=C15OR11;   SMILES=[*]c1c([*])c([*])c(c([*])c1[*])-c1[o+]c2c([*])c([*])c([*])c([*])c2c([*])c1[*];   anthocyanidin cations
 alt_id: CHEBI:13837;   CHEBI:22572;   CHEBI:2751
 xref: HMDB:HMDB0031460;   KEGG:C02003;   MetaCyc:Anthocyanidins;   Wikipedia:Anthocyanidins



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anthocyanin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acta2 actin alpha 2, smooth muscle, aorta decreases expression
multiple interactions
EXP
ISO
Anthocyanins results in decreased expression of ACTA2 mRNA; Anthocyanins results in decreased expression of ACTA2 protein
Anthocyanins inhibits the reaction [Paraquat results in increased expression of ACTA2 mRNA]; Anthocyanins inhibits the reaction [Paraquat results in increased expression of ACTA2 protein]
Anthocyanins inhibits the reaction [Carbon Tetrachloride results in increased expression of ACTA2 protein]
CTD PMID:30056145 PMID:30403199 NCBI chr19:34,217,736...34,232,985
Ensembl chr19:34,218,490...34,232,990
JBrowse link
G Ager advanced glycosylation end product-specific receptor multiple interactions EXP Anthocyanins inhibits the reaction [Dietary Fats results in increased expression of AGER protein] CTD PMID:24795233 NCBI chr17:34,816,545...34,819,911
Ensembl chr17:34,816,836...34,819,910
JBrowse link
G Atm ataxia telangiectasia mutated increases phosphorylation ISO Anthocyanins results in increased phosphorylation of ATM protein CTD PMID:27444805 NCBI chr 9:53,348,422...53,448,125
Ensembl chr 9:53,350,449...53,448,040
JBrowse link
G B2m beta-2 microglobulin multiple interactions ISO Anthocyanins inhibits the reaction [Carbon Tetrachloride results in increased expression of B2M protein] CTD PMID:30825423 NCBI chr 2:121,978,168...121,983,563
Ensembl chr 2:121,978,167...121,983,564
JBrowse link
G Bad BCL2-associated agonist of cell death multiple interactions ISO Anthocyanins inhibits the reaction [Streptozocin results in decreased expression of BAD protein modified form]; Anthocyanins inhibits the reaction [Streptozocin results in increased expression of BAD protein] CTD PMID:28856781 NCBI chr19:6,919,229...6,929,273
Ensembl chr19:6,919,229...6,929,267
JBrowse link
G Bak1 BCL2-antagonist/killer 1 multiple interactions ISO Anthocyanins inhibits the reaction [Streptozocin results in increased expression of BAK1 protein] CTD PMID:28856781 NCBI chr17:27,238,786...27,247,601
Ensembl chr17:27,238,784...27,247,983
JBrowse link
G Bax BCL2-associated X protein multiple interactions ISO Anthocyanins inhibits the reaction [Paraquat results in increased expression of BAX mRNA]; Anthocyanins inhibits the reaction [Paraquat results in increased expression of BAX protein] CTD PMID:30403199 NCBI chr 7:45,111,124...45,116,332
Ensembl chr 7:45,111,121...45,116,322
JBrowse link
G Bcl2 B cell leukemia/lymphoma 2 multiple interactions ISO Anthocyanins inhibits the reaction [Paraquat results in decreased expression of BCL2 mRNA]; Anthocyanins inhibits the reaction [Paraquat results in decreased expression of BCL2 protein]; Anthocyanins inhibits the reaction [Streptozocin results in decreased expression of BCL2 protein] CTD PMID:28856781 PMID:30403199 NCBI chr 1:106,465,906...106,642,020
Ensembl chr 1:106,465,908...106,642,004
JBrowse link
G Bcl2l1 BCL2-like 1 multiple interactions ISO Anthocyanins inhibits the reaction [Streptozocin results in decreased expression of BCL2L1 protein] CTD PMID:28856781 NCBI chr 2:152,600,652...152,673,632
Ensembl chr 2:152,622,588...152,673,648
JBrowse link
G Car1 carbonic anhydrase 1 decreases activity ISO Anthocyanins results in decreased activity of CA1 protein CTD PMID:28445001 NCBI chr 3:14,831,274...14,873,425
Ensembl chr 3:14,831,276...14,873,428
JBrowse link
G Car2 carbonic anhydrase 2 decreases activity ISO Anthocyanins results in decreased activity of CA2 protein CTD PMID:28445001 NCBI chr 3:14,951,329...14,965,830
Ensembl chr 3:14,951,333...14,965,830
JBrowse link
G Casp1 caspase 1 multiple interactions EXP Anthocyanins inhibits the reaction [Dietary Fats results in increased activity of CASP1 protein] CTD PMID:24795233 NCBI chr 9:5,298,517...5,307,281
Ensembl chr 9:5,298,508...5,307,290
JBrowse link
G Casp3 caspase 3 multiple interactions ISO Anthocyanins inhibits the reaction [Streptozocin results in increased cleavage of CASP3 protein] CTD PMID:28856781 NCBI chr 8:47,070,326...47,092,733
Ensembl chr 8:47,070,326...47,092,724
JBrowse link
G Casp8 caspase 8 multiple interactions ISO Anthocyanins inhibits the reaction [Streptozocin results in increased expression of CASP8 protein] CTD PMID:28856781 NCBI chr 1:58,834,553...58,886,663
Ensembl chr 1:58,834,533...58,886,662
JBrowse link
G Casp9 caspase 9 multiple interactions ISO Anthocyanins inhibits the reaction [Streptozocin results in increased expression of CASP9 protein] CTD PMID:28856781 NCBI chr 4:141,520,923...141,543,289
Ensembl chr 4:141,520,923...141,543,287
JBrowse link
G Cat catalase multiple interactions ISO Anthocyanins inhibits the reaction [Carbon Tetrachloride results in decreased activity of CAT protein] CTD PMID:30825423 NCBI chr 2:103,284,249...103,315,498
Ensembl chr 2:103,284,194...103,315,505
JBrowse link
G Ccl2 C-C motif chemokine ligand 2 multiple interactions EXP Anthocyanins inhibits the reaction [Carbon Tetrachloride results in increased expression of CCL2 protein] CTD PMID:30056145 NCBI chr11:81,926,403...81,928,278
Ensembl chr11:81,926,397...81,928,279
JBrowse link
G Ccn2 cellular communication network factor 2 decreases expression EXP Anthocyanins results in decreased expression of CCN2 mRNA CTD PMID:30056145 NCBI chr10:24,471,340...24,474,581
Ensembl chr10:24,471,340...24,474,581
JBrowse link
G Ccnb1 cyclin B1 multiple interactions
increases expression
ISO Anthocyanins promotes the reaction [CDK1 protein binds to CCNB1 protein]
Anthocyanins results in increased expression of CCNB1 protein
CTD PMID:27444805 NCBI chr13:100,915,247...100,922,994
Ensembl chr13:100,915,158...100,923,078
JBrowse link
G Cdc25c cell division cycle 25C increases phosphorylation
multiple interactions
ISO Anthocyanins results in increased phosphorylation of CDC25C protein
Anthocyanins results in decreased expression of and results in increased phosphorylation of CDC25C protein
CTD PMID:27444805 NCBI chr18:34,866,046...34,884,644
Ensembl chr18:34,866,046...34,884,586
JBrowse link
G Cdh1 cadherin 1 multiple interactions ISO Anthocyanins inhibits the reaction [Paraquat results in decreased expression of CDH1 protein] CTD PMID:30403199 NCBI chr 8:107,329,982...107,396,879
Ensembl chr 8:107,329,983...107,396,878
JBrowse link
G Cdk1 cyclin dependent kinase 1 multiple interactions ISO Anthocyanins promotes the reaction [CDK1 protein binds to CCNB1 protein]; Anthocyanins results in increased expression of and results in increased phosphorylation of CDK1 protein CTD PMID:27444805 NCBI chr10:69,170,976...69,188,742
Ensembl chr10:69,170,976...69,188,768
JBrowse link
G Cdkn1a cyclin dependent kinase inhibitor 1A increases expression ISO Anthocyanins results in increased expression of CDKN1A protein CTD PMID:27444805 NCBI chr17:29,309,953...29,319,696
Ensembl chr17:29,309,950...29,319,701
JBrowse link
G Cdkn1b cyclin dependent kinase inhibitor 1B increases expression ISO Anthocyanins results in increased expression of CDKN1B protein CTD PMID:27444805 NCBI chr 6:134,897,364...134,902,488
Ensembl chr 6:134,897,364...134,902,476
JBrowse link
G Chek1 checkpoint kinase 1 increases phosphorylation ISO Anthocyanins results in increased phosphorylation of CHEK1 protein CTD PMID:27444805 NCBI chr 9:36,619,935...36,637,897
Ensembl chr 9:36,619,778...36,638,361
JBrowse link
G Chek2 checkpoint kinase 2 increases phosphorylation ISO Anthocyanins results in increased phosphorylation of CHEK2 protein CTD PMID:27444805 NCBI chr 5:110,987,668...111,022,006
Ensembl chr 5:110,987,845...111,022,011
JBrowse link
G Cldn4 claudin 4 multiple interactions ISO Anthocyanins inhibits the reaction [Cyclophosphamide results in decreased expression of CLDN4 protein] CTD PMID:25451569 NCBI chr 5:134,973,977...134,975,788
Ensembl chr 5:134,973,973...134,975,788
JBrowse link
G Col1a1 collagen, type I, alpha 1 multiple interactions ISO Anthocyanins inhibits the reaction [Paraquat results in increased expression of COL1A1 mRNA] CTD PMID:30403199 NCBI chr11:94,827,050...94,843,868
Ensembl chr11:94,827,050...94,843,868
JBrowse link
G Col3a1 collagen, type III, alpha 1 multiple interactions EXP Anthocyanins inhibits the reaction [Carbon Tetrachloride results in increased expression of COL3A1 protein] CTD PMID:30056145 NCBI chr 1:45,350,698...45,388,866
Ensembl chr 1:45,350,698...45,388,866
JBrowse link
G Ctsd cathepsin D multiple interactions ISO Anthocyanins inhibits the reaction [Cyclophosphamide results in increased activity of CTSD protein] CTD PMID:25451569 NCBI chr 7:141,929,647...141,941,564
Ensembl chr 7:141,929,648...141,941,775
JBrowse link
G Cxcl2 C-X-C motif chemokine ligand 2 multiple interactions EXP Anthocyanins inhibits the reaction [Carbon Tetrachloride results in increased expression of CXCL2] CTD PMID:30056145 NCBI chr 5:91,051,758...91,053,797
Ensembl chr 5:91,051,730...91,053,797
JBrowse link
G Cyp2c52-ps cytochrome P450, family 2, subfamily c, polypeptide 52, pseudogene increases expression ISO Anthocyanins results in increased expression of CYP2C mRNA CTD PMID:18803703 NCBI chr19:38,965,106...38,992,071
Ensembl chr19:38,965,091...38,991,733
JBrowse link
G Cyp2e1 cytochrome P450, family 2, subfamily e, polypeptide 1 increases expression ISO Anthocyanins results in increased expression of CYP2E1 mRNA CTD PMID:18803703 NCBI chr 7:140,343,732...140,354,903
Ensembl chr 7:140,343,652...140,354,900
JBrowse link
G Fadd Fas associated via death domain multiple interactions ISO Anthocyanins inhibits the reaction [Streptozocin results in increased expression of FADD protein] CTD PMID:28856781 NCBI chr 7:144,132,060...144,136,178
Ensembl chr 7:144,131,055...144,136,200
JBrowse link
G Fas Fas cell surface death receptor multiple interactions ISO Anthocyanins inhibits the reaction [Streptozocin results in increased expression of FAS protein] CTD PMID:28856781 NCBI chr19:34,267,926...34,305,175
Ensembl chr19:34,268,066...34,305,172
JBrowse link
G Fasl Fas ligand multiple interactions ISO Anthocyanins inhibits the reaction [Streptozocin results in increased expression of FASLG protein] CTD PMID:28856781 NCBI chr 1:161,608,260...161,616,064
Ensembl chr 1:161,608,258...161,616,064
JBrowse link
G Gsr glutathione reductase multiple interactions ISO Anthocyanins inhibits the reaction [Carbon Tetrachloride results in decreased activity of GSR protein] CTD PMID:30825423 NCBI chr 8:34,143,266...34,188,190
Ensembl chr 8:34,142,551...34,188,191
JBrowse link
G Gusb glucuronidase, beta multiple interactions ISO Anthocyanins inhibits the reaction [Cyclophosphamide results in increased activity of GUSB protein] CTD PMID:25451569 NCBI chr 5:130,011,278...130,031,890
Ensembl chr 5:130,017,852...130,031,890
JBrowse link
G H2ax H2A.X variant histone increases phosphorylation ISO Anthocyanins results in increased phosphorylation of H2AX protein CTD PMID:27444805 NCBI chr 9:44,246,012...44,247,374
Ensembl chr 9:44,245,991...44,247,374
JBrowse link
G Havcr1 hepatitis A virus cellular receptor 1 multiple interactions ISO Anthocyanins inhibits the reaction [Carbon Tetrachloride results in increased expression of HAVCR1 protein] CTD PMID:30825423 NCBI chr11:46,630,644...46,670,405
Ensembl chr11:46,625,907...46,670,405
JBrowse link
G Ikbkb inhibitor of kappaB kinase beta multiple interactions EXP Anthocyanins inhibits the reaction [Dietary Fats results in increased phosphorylation of IKBKB protein] CTD PMID:24795233 NCBI chr 8:23,149,228...23,196,605
Ensembl chr 8:23,149,228...23,196,605
JBrowse link
G Il10 interleukin 10 multiple interactions ISO Anthocyanins inhibits the reaction [Cyclophosphamide results in decreased expression of IL10 protein] CTD PMID:25451569 NCBI chr 1:130,947,459...130,952,707
Ensembl chr 1:130,947,582...130,952,711
JBrowse link
G Il1b interleukin 1 beta multiple interactions ISO
EXP
Anthocyanins inhibits the reaction [Cyclophosphamide results in increased expression of IL1B protein]
Anthocyanins inhibits the reaction [Carbon Tetrachloride results in increased expression of IL1B protein]; Anthocyanins inhibits the reaction [Dietary Fats results in increased expression of IL1B protein]
CTD PMID:24795233 PMID:25451569 PMID:30056145 NCBI chr 2:129,206,490...129,213,059
Ensembl chr 2:129,206,490...129,213,059
JBrowse link
G Lcn2 lipocalin 2 multiple interactions ISO Anthocyanins inhibits the reaction [Carbon Tetrachloride results in increased expression of LCN2 protein] CTD PMID:30825423 NCBI chr 2:32,274,649...32,277,751
Ensembl chr 2:32,274,645...32,278,264
JBrowse link
G Mmp9 matrix metallopeptidase 9 multiple interactions EXP Anthocyanins inhibits the reaction [Carbon Tetrachloride results in decreased expression of MMP9 protein] CTD PMID:30056145 NCBI chr 2:164,782,246...164,797,770
Ensembl chr 2:164,782,700...164,797,770
JBrowse link
G Mpo myeloperoxidase multiple interactions ISO Anthocyanins inhibits the reaction [Carbon Tetrachloride results in increased activity of MPO protein]; Anthocyanins inhibits the reaction [Cyclophosphamide results in increased activity of MPO protein] CTD PMID:25451569 PMID:30825423 NCBI chr11:87,684,610...87,695,238
Ensembl chr11:87,684,407...87,695,239
JBrowse link
G Nfkbia nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, alpha multiple interactions EXP Anthocyanins inhibits the reaction [Dietary Fats results in increased degradation of NFKBIA protein] CTD PMID:24795233 NCBI chr12:55,536,194...55,539,432
Ensembl chr12:55,536,195...55,539,432
JBrowse link
G Nlrp3 NLR family, pyrin domain containing 3 multiple interactions EXP Anthocyanins inhibits the reaction [Dietary Fats results in increased expression of NLRP3 protein] CTD PMID:24795233 NCBI chr11:59,432,395...59,457,781
Ensembl chr11:59,432,394...59,457,782
JBrowse link
G Nos2 nitric oxide synthase 2, inducible multiple interactions EXP Anthocyanins inhibits the reaction [Dietary Fats results in increased expression of NOS2 protein] CTD PMID:24795233 NCBI chr11:78,811,613...78,851,052
Ensembl chr11:78,811,613...78,851,080
JBrowse link
G Parp1 poly (ADP-ribose) polymerase family, member 1 multiple interactions ISO Anthocyanins inhibits the reaction [Streptozocin results in increased cleavage of PARP1 protein] CTD PMID:28856781 NCBI chr 1:180,396,456...180,428,564
Ensembl chr 1:180,396,489...180,428,819
JBrowse link
G Pcna proliferating cell nuclear antigen multiple interactions EXP Anthocyanins inhibits the reaction [Carbon Tetrachloride results in increased expression of PCNA protein] CTD PMID:30056145 NCBI chr 2:132,091,206...132,095,100
Ensembl chr 2:132,091,082...132,095,234
JBrowse link
G Pde5a phosphodiesterase 5A, cGMP-specific decreases activity ISO Anthocyanins results in decreased activity of PDE5A protein CTD PMID:15769121 NCBI chr 3:122,522,822...122,653,023
Ensembl chr 3:122,522,596...122,653,023
JBrowse link
G Pik3r1 phosphoinositide-3-kinase regulatory subunit 1 increases expression ISO Anthocyanins results in increased expression of PIK3R1 mRNA CTD PMID:18803703 NCBI chr13:101,817,269...101,904,725
Ensembl chr13:101,817,071...101,904,725
JBrowse link
G Pla2g2a phospholipase A2, group IIA (platelets, synovial fluid) increases expression ISO Anthocyanins results in increased expression of PLA2G2A mRNA CTD PMID:18803703 NCBI chr 4:138,559,168...138,562,500
Ensembl chr 4:138,559,171...138,562,497
JBrowse link
G Plcd4 phospholipase C, delta 4 increases expression ISO Anthocyanins results in increased expression of PLCD4 mRNA CTD PMID:18803703 NCBI chr 1:74,581,175...74,605,137
Ensembl chr 1:74,582,047...74,606,953
JBrowse link
G Por cytochrome p450 oxidoreductase increases expression ISO Anthocyanins results in increased expression of POR mRNA CTD PMID:18803703 NCBI chr 5:135,698,894...135,764,180
Ensembl chr 5:135,698,887...135,764,180
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 multiple interactions EXP Anthocyanins inhibits the reaction [Dietary Fats results in increased expression of PTGS2 protein] CTD PMID:24795233 NCBI chr 1:149,975,851...149,983,978
Ensembl chr 1:149,975,782...149,983,978
JBrowse link
G Pycard PYD and CARD domain containing multiple interactions EXP Anthocyanins inhibits the reaction [Dietary Fats results in increased expression of PYCARD protein] CTD PMID:24795233 NCBI chr 7:127,590,545...127,593,039
Ensembl chr 7:127,588,880...127,593,039
JBrowse link
G Rela v-rel reticuloendotheliosis viral oncogene homolog A (avian) multiple interactions ISO Anthocyanins inhibits the reaction [Cyclophosphamide results in increased activity of RELA protein] CTD PMID:25451569 NCBI chr19:5,686,993...5,698,162
Ensembl chr19:5,687,511...5,698,158
JBrowse link
G Smad2 SMAD family member 2 multiple interactions ISO Anthocyanins inhibits the reaction [Paraquat results in increased phosphorylation of SMAD2 protein] CTD PMID:30403199 NCBI chr18:76,369,898...76,444,819
Ensembl chr18:76,374,651...76,444,034
JBrowse link
G Snca synuclein, alpha decreases expression ISO Anthocyanins results in decreased expression of SNCA protein CTD PMID:29976995 NCBI chr 6:60,708,557...60,806,839
Ensembl chr 6:60,708,559...60,806,839
JBrowse link
G Tgfb1 transforming growth factor, beta 1 decreases expression
multiple interactions
EXP
ISO
Anthocyanins results in decreased expression of TGFB1 mRNA
Anthocyanins inhibits the reaction [Paraquat results in increased expression of TGFB1 protein]
CTD PMID:30056145 PMID:30403199 NCBI chr 7:25,386,406...25,404,503
Ensembl chr 7:25,386,427...25,404,502
JBrowse link
G Tgfbr1 transforming growth factor, beta receptor I multiple interactions ISO Anthocyanins inhibits the reaction [Paraquat results in increased expression of TGFBR1 protein] CTD PMID:30403199 NCBI chr 4:47,353,258...47,414,926
Ensembl chr 4:47,353,222...47,414,931
JBrowse link
G Timp1 tissue inhibitor of metalloproteinase 1 multiple interactions EXP Anthocyanins inhibits the reaction [Carbon Tetrachloride results in increased expression of TIMP1 protein] CTD PMID:30056145 NCBI chr  X:20,736,524...20,740,972
Ensembl chr  X:20,736,405...20,740,974
JBrowse link
G Tjp1 tight junction protein 1 multiple interactions ISO Anthocyanins inhibits the reaction [Cyclophosphamide results in decreased expression of TJP1 protein] CTD PMID:25451569 NCBI chr 7:64,945,913...65,177,629
Ensembl chr 7:64,945,913...65,177,529
JBrowse link
G Tnf tumor necrosis factor multiple interactions ISO
EXP
Anthocyanins inhibits the reaction [Carbon Tetrachloride results in increased expression of TNF protein]; Anthocyanins inhibits the reaction [Cyclophosphamide results in increased expression of TNF protein]
Anthocyanins inhibits the reaction [Lipopolysaccharides results in increased expression of TNF]
CTD PMID:18720166 PMID:25451569 PMID:30825423 NCBI chr17:35,418,343...35,420,983
Ensembl chr17:35,418,357...35,420,983
JBrowse link
G Txnip thioredoxin interacting protein multiple interactions EXP Anthocyanins inhibits the reaction [Dietary Fats results in increased expression of TXNIP protein] CTD PMID:24795233 NCBI chr 3:96,465,273...96,469,173
Ensembl chr 3:96,465,273...96,469,199
JBrowse link
G Vim vimentin multiple interactions ISO Anthocyanins inhibits the reaction [Paraquat results in increased expression of VIM mRNA]; Anthocyanins inhibits the reaction [Paraquat results in increased expression of VIM protein] CTD PMID:30403199 NCBI chr 2:13,579,122...13,587,637
Ensembl chr 2:13,578,738...13,587,637
JBrowse link
G Xdh xanthine dehydrogenase multiple interactions ISO Anthocyanins inhibits the reaction [Carbon Tetrachloride results in increased activity of XDH protein] CTD PMID:30825423 NCBI chr17:74,190,890...74,257,191
Ensembl chr17:74,190,890...74,257,191
JBrowse link
cyanidin cation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ahr aryl-hydrocarbon receptor increases activity ISO cyanidin results in increased activity of AHR protein CTD PMID:23419638 NCBI chr12:35,547,978...35,584,988
Ensembl chr12:35,547,973...35,585,037
JBrowse link
G Ccn1 cellular communication network factor 1 multiple interactions EXP
ISO
cyanidin inhibits the reaction [[IL17A protein co-treated with Freund's Adjuvant] results in increased expression of CCN1 protein]
cyanidin inhibits the reaction [Freund's Adjuvant results in increased expression of CCN1 protein]
CTD PMID:32044269 NCBI chr 3:145,352,726...145,355,740
Ensembl chr 3:145,352,731...145,355,736
JBrowse link
G Csf2 colony stimulating factor 2 (granulocyte-macrophage) multiple interactions EXP
ISO
cyanidin inhibits the reaction [[IL17A protein co-treated with Freund's Adjuvant] results in increased expression of CSF2 mRNA]; cyanidin inhibits the reaction [[IL17A protein co-treated with Freund's Adjuvant] results in increased expression of CSF2 protein]
cyanidin inhibits the reaction [Freund's Adjuvant results in increased expression of CSF2 protein]
CTD PMID:32044269 NCBI chr11:54,138,096...54,140,725
Ensembl chr11:54,138,097...54,140,493
JBrowse link
G Hbegf heparin-binding EGF-like growth factor multiple interactions ISO cyanidin inhibits the reaction [Sodium Chloride results in increased expression of HBEGF mRNA] CTD PMID:26800359 NCBI chr18:36,637,980...36,648,858
Ensembl chr18:36,637,980...36,648,858
JBrowse link
G Hlcs holocarboxylase synthetase (biotin- [propriony-Coenzyme A-carboxylase (ATP-hydrolysing)] ligase) decreases activity ISO cyanidin results in decreased activity of HLCS protein CTD PMID:26303405 NCBI chr16:93,930,054...94,116,098
Ensembl chr16:93,929,741...94,114,430
JBrowse link
G Hmox1 heme oxygenase 1 affects expression EXP cyanidin affects the expression of HMOX1 protein CTD PMID:26505893 NCBI chr 8:75,820,246...75,827,221
Ensembl chr 8:75,820,249...75,827,217
JBrowse link
G Il17a interleukin 17A multiple interactions EXP [cyanidin inhibits the reaction [[IL17A protein co-treated with Freund's Adjuvant] results in increased expression of and results in increased phosphorylation of STAT3 protein]] which results in increased expression of PIAS3 protein; cyanidin inhibits the reaction [[IL17A protein co-treated with Freund's Adjuvant] results in increased expression of and results in increased phosphorylation of STAT3 protein]; cyanidin inhibits the reaction [[IL17A protein co-treated with Freund's Adjuvant] results in increased expression of CCN1 protein]; cyanidin inhibits the reaction [[IL17A protein co-treated with Freund's Adjuvant] results in increased expression of CSF2 mRNA]; cyanidin inhibits the reaction [[IL17A protein co-treated with Freund's Adjuvant] results in increased expression of CSF2 protein]; cyanidin inhibits the reaction [[IL17A protein co-treated with Freund's Adjuvant] results in increased expression of IL17RA mRNA]; cyanidin inhibits the reaction [[IL17A protein co-treated with Freund's Adjuvant] results in increased expression of IL17RA protein]; cyanidin inhibits the reaction [[IL17A protein co-treated with Freund's Adjuvant] results in increased expression of IL23A mRNA]; cyanidin inhibits the reaction [[IL17A protein co-treated with Freund's Adjuvant] results in increased expression of IL23A protein]; cyanidin inhibits the reaction [[IL17A protein co-treated with Freund's Adjuvant] results in increased expression of PCNA protein]; cyanidin inhibits the reaction [[IL17A protein co-treated with Freund's Adjuvant] results in increased expression of TLR3 protein]; cyanidin inhibits the reaction [[IL17A protein co-treated with Freund's Adjuvant] results in increased phosphorylation of JAK1 protein]; cyanidin inhibits the reaction [[IL17A protein co-treated with Freund's Adjuvant] results in increased phosphorylation of JAK3 protein]; cyanidin inhibits the reaction [IL17A protein promotes the reaction [Freund's Adjuvant results in increased expression of TLR3 protein]] CTD PMID:32044269 NCBI chr 1:20,801,129...20,804,720
Ensembl chr 1:20,801,129...20,804,720
JBrowse link
G Il17ra interleukin 17 receptor A multiple interactions EXP cyanidin inhibits the reaction [[IL17A protein co-treated with Freund's Adjuvant] results in increased expression of IL17RA mRNA]; cyanidin inhibits the reaction [[IL17A protein co-treated with Freund's Adjuvant] results in increased expression of IL17RA protein] CTD PMID:32044269 NCBI chr 6:120,440,143...120,460,692
Ensembl chr 6:120,440,208...120,464,520
JBrowse link
G Il23a interleukin 23, alpha subunit p19 multiple interactions EXP
ISO
cyanidin inhibits the reaction [[IL17A protein co-treated with Freund's Adjuvant] results in increased expression of IL23A mRNA]; cyanidin inhibits the reaction [[IL17A protein co-treated with Freund's Adjuvant] results in increased expression of IL23A protein]
cyanidin inhibits the reaction [Freund's Adjuvant results in increased expression of IL23A protein]
CTD PMID:32044269 NCBI chr10:128,132,009...128,133,953
Ensembl chr10:128,132,008...128,134,621
JBrowse link
G Jak1 Janus kinase 1 multiple interactions EXP cyanidin inhibits the reaction [[IL17A protein co-treated with Freund's Adjuvant] results in increased phosphorylation of JAK1 protein] CTD PMID:32044269 NCBI chr 4:101,009,171...101,122,493
Ensembl chr 4:101,009,564...101,122,479
JBrowse link
G Jak3 Janus kinase 3 multiple interactions EXP cyanidin inhibits the reaction [[IL17A protein co-treated with Freund's Adjuvant] results in increased phosphorylation of JAK3 protein] CTD PMID:32044269 NCBI chr 8:72,129,027...72,143,221
Ensembl chr 8:72,128,940...72,143,219
JBrowse link
G Nfe2l2 nuclear factor, erythroid derived 2, like 2 increases activity
affects expression
ISO
EXP
cyanidin results in increased activity of NFE2L2 protein
cyanidin affects the expression of NFE2L2 protein
CTD PMID:26505893 PMID:27166148 NCBI chr 2:75,505,860...75,535,007
Ensembl chr 2:75,505,857...75,534,985
JBrowse link
G Nos3 nitric oxide synthase 3, endothelial cell increases expression ISO cyanidin results in increased expression of NOS3 mRNA CTD PMID:15740983 NCBI chr 5:24,569,772...24,589,472
Ensembl chr 5:24,569,808...24,589,472
JBrowse link
G Pcna proliferating cell nuclear antigen multiple interactions EXP cyanidin inhibits the reaction [[IL17A protein co-treated with Freund's Adjuvant] results in increased expression of PCNA protein] CTD PMID:32044269 NCBI chr 2:132,091,206...132,095,100
Ensembl chr 2:132,091,082...132,095,234
JBrowse link
G Pdgfa platelet derived growth factor, alpha multiple interactions ISO cyanidin inhibits the reaction [[PDGFA protein co-treated with PDGFB protein] results in increased abundance of Reactive Oxygen Species]; cyanidin inhibits the reaction [[PDGFA protein co-treated with PDGFB protein] results in increased secretion of VEGFA protein] CTD PMID:16921400 NCBI chr 5:138,961,761...138,986,336
Ensembl chr 5:138,961,769...138,983,125
JBrowse link
G Pdgfb platelet derived growth factor, B polypeptide multiple interactions ISO cyanidin inhibits the reaction [[PDGFA protein co-treated with PDGFB protein] results in increased abundance of Reactive Oxygen Species]; cyanidin inhibits the reaction [[PDGFA protein co-treated with PDGFB protein] results in increased secretion of VEGFA protein] CTD PMID:16921400 NCBI chr15:79,880,066...79,899,178
Ensembl chr15:79,880,075...79,899,178
JBrowse link
G Pias3 protein inhibitor of activated STAT 3 multiple interactions EXP [cyanidin inhibits the reaction [[IL17A protein co-treated with Freund's Adjuvant] results in increased expression of and results in increased phosphorylation of STAT3 protein]] which results in increased expression of PIAS3 protein CTD PMID:32044269 NCBI chr 3:96,603,679...96,613,386
Ensembl chr 3:96,603,700...96,613,386
JBrowse link
G Stat3 signal transducer and activator of transcription 3 multiple interactions ISO
EXP
cyanidin inhibits the reaction [Freund's Adjuvant results in increased phosphorylation of STAT3 protein]
[cyanidin inhibits the reaction [[IL17A protein co-treated with Freund's Adjuvant] results in increased expression of and results in increased phosphorylation of STAT3 protein]] which results in increased expression of PIAS3 protein; cyanidin inhibits the reaction [[IL17A protein co-treated with Freund's Adjuvant] results in increased expression of and results in increased phosphorylation of STAT3 protein]
CTD PMID:32044269 NCBI chr11:100,777,632...100,830,447
Ensembl chr11:100,775,924...100,830,366
JBrowse link
G Tlr3 toll-like receptor 3 multiple interactions EXP
ISO
cyanidin inhibits the reaction [[IL17A protein co-treated with Freund's Adjuvant] results in increased expression of TLR3 protein]; cyanidin inhibits the reaction [IL17A protein promotes the reaction [Freund's Adjuvant results in increased expression of TLR3 protein]]
cyanidin inhibits the reaction [Freund's Adjuvant results in increased expression of TLR3 protein]
CTD PMID:32044269 NCBI chr 8:45,848,702...45,864,112
Ensembl chr 8:45,848,702...45,864,117
JBrowse link
G Tnf tumor necrosis factor multiple interactions EXP cyanidin inhibits the reaction [Benzo(a)pyrene results in increased expression of TNF mRNA] CTD PMID:28533128 NCBI chr17:35,418,343...35,420,983
Ensembl chr17:35,418,357...35,420,983
JBrowse link
G Ucp2 uncoupling protein 2 (mitochondrial, proton carrier) multiple interactions EXP cyanidin inhibits the reaction [Benzo(a)pyrene results in increased expression of UCP2 mRNA] CTD PMID:28533128 NCBI chr 7:100,142,565...100,148,832
Ensembl chr 7:100,142,544...100,151,227
JBrowse link
G Vegfa vascular endothelial growth factor A multiple interactions ISO cyanidin inhibits the reaction [[PDGFA protein co-treated with PDGFB protein] results in increased secretion of VEGFA protein]; cyanidin inhibits the reaction [cobaltous chloride results in increased expression of VEGFA mRNA] CTD PMID:16921400 PMID:26800359 NCBI chr17:46,327,919...46,343,303
Ensembl chr17:46,327,919...46,343,295
JBrowse link
delphinidin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acta2 actin alpha 2, smooth muscle, aorta multiple interactions EXP delphinidin inhibits the reaction [Carbon Tetrachloride results in increased expression of ACTA2 protein] CTD PMID:20371262 NCBI chr19:34,217,736...34,232,985
Ensembl chr19:34,218,490...34,232,990
JBrowse link
G Arnt aryl hydrocarbon receptor nuclear translocator multiple interactions ISO delphinidin inhibits the reaction [Hydrogen Peroxide results in increased expression of ARNT protein] CTD PMID:18603805 NCBI chr 3:95,341,674...95,404,551
Ensembl chr 3:95,341,699...95,404,551
JBrowse link
G Bad BCL2-associated agonist of cell death increases expression ISO delphinidin results in increased expression of BAD protein CTD PMID:33955636 NCBI chr19:6,919,229...6,929,273
Ensembl chr19:6,919,229...6,929,267
JBrowse link
G Bak1 BCL2-antagonist/killer 1 increases expression ISO delphinidin results in increased expression of BAK1 protein CTD PMID:29451351 NCBI chr17:27,238,786...27,247,601
Ensembl chr17:27,238,784...27,247,983
JBrowse link
G Bax BCL2-associated X protein increases expression
multiple interactions
decreases expression
ISO delphinidin results in increased expression of BAX protein
2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [delphinidin promotes the reaction [TGFB1 results in decreased expression of BAX protein]]; delphinidin promotes the reaction [TGFB1 results in decreased expression of BAX protein]
delphinidin results in decreased expression of BAX protein
CTD PMID:15740068 PMID:19818742 PMID:30365941 PMID:33955636 NCBI chr 7:45,111,124...45,116,332
Ensembl chr 7:45,111,121...45,116,322
JBrowse link
G Bcl2 B cell leukemia/lymphoma 2 decreases expression
multiple interactions
increases expression
ISO delphinidin results in decreased expression of BCL2 protein
2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [delphinidin inhibits the reaction [TGFB1 results in decreased expression of BCL2 protein]]; delphinidin inhibits the reaction [TGFB1 results in decreased expression of BCL2 protein]
delphinidin results in increased expression of BCL2 protein
CTD PMID:15740068 PMID:19818742 PMID:29451351 PMID:30365941 PMID:33955636 NCBI chr 1:106,465,906...106,642,020
Ensembl chr 1:106,465,908...106,642,004
JBrowse link
G Bcl2l1 BCL2-like 1 decreases expression ISO delphinidin results in decreased expression of BCL2L1 protein CTD PMID:33955636 NCBI chr 2:152,600,652...152,673,632
Ensembl chr 2:152,622,588...152,673,648
JBrowse link
G Bid BH3 interacting domain death agonist multiple interactions
decreases expression
ISO [delphinidin results in increased susceptibility to sodium arsenite] which results in decreased expression of BID protein
delphinidin results in decreased expression of BID protein
CTD PMID:25954945 PMID:30125548 NCBI chr 6:120,870,080...120,894,074
Ensembl chr 6:120,868,891...120,893,814
JBrowse link
G Btg2 BTG anti-proliferation factor 2 affects expression ISO delphinidin affects the expression of BTG2 mRNA CTD PMID:19182879 NCBI chr 1:134,002,603...134,006,893
Ensembl chr 1:134,002,908...134,006,858
JBrowse link
G Casp3 caspase 3 increases activity
increases expression
multiple interactions
increases cleavage
ISO delphinidin results in increased activity of CASP3 protein
delphinidin results in increased expression of CASP3 protein
2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [delphinidin inhibits the reaction [TGFB1 results in increased expression of CASP3 protein]]; [delphinidin results in increased susceptibility to sodium arsenite] which results in increased cleavage of CASP3 protein; delphinidin inhibits the reaction [TGFB1 results in increased expression of CASP3 protein]; delphinidin results in increased cleavage of and results in increased activity of CASP3 protein
delphinidin results in increased cleavage of CASP3 protein
CTD PMID:15740068 PMID:25954945 PMID:29451351 PMID:30125548 PMID:30365941 More... NCBI chr 8:47,070,326...47,092,733
Ensembl chr 8:47,070,326...47,092,724
JBrowse link
G Casp8 caspase 8 multiple interactions
increases expression
ISO [delphinidin results in increased susceptibility to sodium arsenite] which results in increased cleavage of CASP8 protein; delphinidin results in increased cleavage of and results in increased activity of CASP8 protein
delphinidin results in increased expression of CASP8 protein
CTD PMID:25954945 PMID:30125548 PMID:33955636 NCBI chr 1:58,834,553...58,886,663
Ensembl chr 1:58,834,533...58,886,662
JBrowse link
G Casp9 caspase 9 multiple interactions
increases expression
ISO [delphinidin results in increased susceptibility to sodium arsenite] which results in increased cleavage of CASP9 protein; delphinidin results in increased cleavage of and results in increased activity of CASP9 protein
delphinidin results in increased expression of CASP9 protein
CTD PMID:25954945 PMID:30125548 PMID:33955636 NCBI chr 4:141,520,923...141,543,289
Ensembl chr 4:141,520,923...141,543,287
JBrowse link
G Cat catalase decreases activity ISO delphinidin results in decreased activity of CAT protein CTD PMID:33955636 NCBI chr 2:103,284,249...103,315,498
Ensembl chr 2:103,284,194...103,315,505
JBrowse link
G Cdh1 cadherin 1 increases expression ISO delphinidin results in increased expression of CDH1 protein CTD PMID:29451351 NCBI chr 8:107,329,982...107,396,879
Ensembl chr 8:107,329,983...107,396,878
JBrowse link
G Cdh2 cadherin 2 decreases expression ISO delphinidin results in decreased expression of CDH2 protein CTD PMID:29451351 NCBI chr18:16,721,934...16,942,303
Ensembl chr18:16,721,934...16,942,303
JBrowse link
G Cidea cell death-inducing DNA fragmentation factor, alpha subunit-like effector A increases expression ISO delphinidin results in increased expression of CIDEA mRNA CTD PMID:19182879 NCBI chr18:67,476,634...67,500,864
Ensembl chr18:67,476,674...67,500,855
JBrowse link
G Cycs cytochrome c, somatic increases expression ISO delphinidin results in increased expression of CYCS protein CTD PMID:33955636 NCBI chr 6:50,539,543...50,543,549
Ensembl chr 6:50,539,543...50,543,518
JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 decreases activity ISO delphinidin results in decreased activity of CYP1A1 protein CTD PMID:23419638 NCBI chr 9:57,595,211...57,611,107
Ensembl chr 9:57,595,211...57,611,107
JBrowse link
G Egfr epidermal growth factor receptor decreases phosphorylation ISO delphinidin results in decreased phosphorylation of EGFR protein CTD PMID:18618485 NCBI chr11:16,700,153...16,868,158
Ensembl chr11:16,702,203...16,868,158
JBrowse link
G Epas1 endothelial PAS domain protein 1 multiple interactions ISO delphinidin inhibits the reaction [Hydrogen Peroxide results in increased expression of EPAS1 protein] CTD PMID:18603805 NCBI chr17:87,061,292...87,140,838
Ensembl chr17:87,061,128...87,140,838
JBrowse link
G Erbb2 erb-b2 receptor tyrosine kinase 2 decreases phosphorylation ISO delphinidin results in decreased phosphorylation of ERBB2 protein CTD PMID:18618485 NCBI chr11:98,303,310...98,328,542
Ensembl chr11:98,303,296...98,328,542
JBrowse link
G Hif1a hypoxia inducible factor 1, alpha subunit multiple interactions ISO delphinidin inhibits the reaction [Hydrogen Peroxide results in increased expression of HIF1A protein] CTD PMID:18603805 NCBI chr12:73,948,186...73,994,304
Ensembl chr12:73,948,149...73,994,304
JBrowse link
G Hif3a hypoxia inducible factor 3, alpha subunit multiple interactions ISO delphinidin inhibits the reaction [Hydrogen Peroxide results in increased expression of HIF3A protein] CTD PMID:18603805 NCBI chr 7:16,764,918...16,796,352
Ensembl chr 7:16,765,432...16,796,352
JBrowse link
G Hmox1 heme oxygenase 1 increases expression ISO delphinidin results in increased expression of HMOX1 protein CTD PMID:30266311 NCBI chr 8:75,820,246...75,827,221
Ensembl chr 8:75,820,249...75,827,217
JBrowse link
G Jak2 Janus kinase 2 decreases phosphorylation ISO delphinidin results in decreased phosphorylation of JAK2 protein CTD PMID:33955636 NCBI chr19:29,229,006...29,290,495
Ensembl chr19:29,229,228...29,290,480
JBrowse link
G Jun jun proto-oncogene increases expression ISO delphinidin results in increased expression of JUN mRNA CTD PMID:15740068 NCBI chr 4:94,937,273...94,940,459
Ensembl chr 4:94,937,271...94,940,459
JBrowse link
G Mapk1 mitogen-activated protein kinase 1 decreases phosphorylation ISO delphinidin results in decreased phosphorylation of MAPK1 protein CTD PMID:18618485 PMID:29451351 PMID:33955636 NCBI chr16:16,801,246...16,865,317
Ensembl chr16:16,801,246...16,865,317
JBrowse link
G Mapk3 mitogen-activated protein kinase 3 decreases phosphorylation ISO delphinidin results in decreased phosphorylation of MAPK3 protein CTD PMID:18618485 PMID:29451351 PMID:33955636 NCBI chr 7:126,358,798...126,364,988
Ensembl chr 7:126,358,773...126,364,991
JBrowse link
G Mapk8 mitogen-activated protein kinase 8 multiple interactions ISO delphinidin results in increased phosphorylation of and results in increased activity of MAPK8 protein CTD PMID:15740068 NCBI chr14:33,099,855...33,169,213
Ensembl chr14:33,099,855...33,169,115
JBrowse link
G Mmp9 matrix metallopeptidase 9 multiple interactions EXP delphinidin promotes the reaction [Carbon Tetrachloride results in increased expression of MMP9 protein] CTD PMID:20371262 NCBI chr 2:164,782,246...164,797,770
Ensembl chr 2:164,782,700...164,797,770
JBrowse link
G Nbn nibrin increases expression ISO delphinidin results in increased expression of NBN mRNA CTD PMID:19182879 NCBI chr 4:15,955,388...15,992,589
Ensembl chr 4:15,957,925...15,992,589
JBrowse link
G Parp1 poly (ADP-ribose) polymerase family, member 1 decreases activity
increases cleavage
ISO delphinidin results in decreased activity of PARP1 protein
delphinidin results in increased cleavage of PARP1 protein
CTD PMID:17884996 PMID:29451351 NCBI chr 1:180,396,456...180,428,564
Ensembl chr 1:180,396,489...180,428,819
JBrowse link
G Pcbp4 poly(rC) binding protein 4 affects expression ISO delphinidin affects the expression of PCBP4 mRNA CTD PMID:19182879 NCBI chr 9:106,330,181...106,341,211
Ensembl chr 9:106,330,490...106,341,211
JBrowse link
G Pdgfa platelet derived growth factor, alpha multiple interactions ISO delphinidin inhibits the reaction [[PDGFA protein co-treated with PDGFB protein] results in increased abundance of Reactive Oxygen Species]; delphinidin inhibits the reaction [[PDGFA protein co-treated with PDGFB protein] results in increased secretion of VEGFA protein] CTD PMID:16921400 NCBI chr 5:138,961,761...138,986,336
Ensembl chr 5:138,961,769...138,983,125
JBrowse link
G Pdgfb platelet derived growth factor, B polypeptide multiple interactions ISO delphinidin inhibits the reaction [[PDGFA protein co-treated with PDGFB protein] results in increased abundance of Reactive Oxygen Species]; delphinidin inhibits the reaction [[PDGFA protein co-treated with PDGFB protein] results in increased secretion of VEGFA protein] CTD PMID:16921400 NCBI chr15:79,880,066...79,899,178
Ensembl chr15:79,880,075...79,899,178
JBrowse link
G Pgk1 phosphoglycerate kinase 1 multiple interactions ISO delphinidin inhibits the reaction [Hydrogen Peroxide results in increased expression of PGK1 protein] CTD PMID:18603805 NCBI chr  X:105,230,706...105,247,305
Ensembl chr  X:105,230,706...105,247,305
JBrowse link
G Snai1 snail family zinc finger 1 decreases expression ISO delphinidin results in decreased expression of SNAI1 protein CTD PMID:29451351 NCBI chr 2:167,380,115...167,384,734
Ensembl chr 2:167,380,115...167,384,734
JBrowse link
G Snai2 snail family zinc finger 2 decreases expression ISO delphinidin results in decreased expression of SNAI2 protein CTD PMID:29451351 NCBI chr16:14,523,716...14,527,259
Ensembl chr16:14,523,716...14,527,249
JBrowse link
G Stat3 signal transducer and activator of transcription 3 decreases phosphorylation ISO delphinidin results in decreased phosphorylation of STAT3 protein CTD PMID:33955636 NCBI chr11:100,777,632...100,830,447
Ensembl chr11:100,775,924...100,830,366
JBrowse link
G Tgfb1 transforming growth factor, beta 1 multiple interactions EXP
ISO
delphinidin inhibits the reaction [Carbon Tetrachloride results in increased expression of TGFB1 protein]
2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [delphinidin inhibits the reaction [TGFB1 results in decreased expression of BCL2 protein]]; 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [delphinidin inhibits the reaction [TGFB1 results in increased expression of CASP3 protein]]; 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [delphinidin promotes the reaction [TGFB1 results in decreased expression of BAX protein]]; delphinidin inhibits the reaction [TGFB1 results in decreased expression of BCL2 protein]; delphinidin inhibits the reaction [TGFB1 results in increased abundance of Malondialdehyde]; delphinidin inhibits the reaction [TGFB1 results in increased abundance of Reactive Oxygen Species]; delphinidin inhibits the reaction [TGFB1 results in increased expression of CASP3 protein]; delphinidin promotes the reaction [TGFB1 results in decreased expression of BAX protein]
CTD PMID:20371262 PMID:30365941 NCBI chr 7:25,386,406...25,404,503
Ensembl chr 7:25,386,427...25,404,502
JBrowse link
G Tnf tumor necrosis factor multiple interactions EXP delphinidin inhibits the reaction [Carbon Tetrachloride results in increased expression of TNF protein] CTD PMID:20371262 NCBI chr17:35,418,343...35,420,983
Ensembl chr17:35,418,357...35,420,983
JBrowse link
G Top1 topoisomerase (DNA) I decreases activity ISO delphinidin results in decreased activity of TOP1 protein CTD PMID:19182879 NCBI chr 2:160,487,901...160,564,684
Ensembl chr 2:160,487,808...160,564,684
JBrowse link
G Top2a topoisomerase (DNA) II alpha decreases activity
multiple interactions
ISO delphinidin results in decreased activity of TOP2A protein
delphinidin results in decreased susceptibility to [Doxorubicin affects the activity of TOP2A protein]; delphinidin results in decreased susceptibility to [Etoposide affects the activity of TOP2A protein]
CTD PMID:19182879 NCBI chr11:98,883,773...98,915,037
Ensembl chr11:98,883,769...98,915,015
JBrowse link
G Vegfa vascular endothelial growth factor A multiple interactions ISO delphinidin inhibits the reaction [[PDGFA protein co-treated with PDGFB protein] results in increased secretion of VEGFA protein] CTD PMID:16921400 NCBI chr17:46,327,919...46,343,303
Ensembl chr17:46,327,919...46,343,295
JBrowse link
luteolinidin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hsd17b7 hydroxysteroid (17-beta) dehydrogenase 7 increases expression ISO luteolinidin results in increased expression of HSD17B7 mRNA CTD PMID:31201582 NCBI chr 1:169,777,109...169,796,757
Ensembl chr 1:169,777,104...169,796,810
JBrowse link
G Nfe2 nuclear factor, erythroid derived 2 increases expression ISO luteolinidin results in increased expression of NFE2 mRNA CTD PMID:31201582 NCBI chr15:103,156,640...103,166,809
Ensembl chr15:103,156,639...103,166,830
JBrowse link
malvidin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Akt1 thymoma viral proto-oncogene 1 multiple interactions EXP malvidin promotes the reaction [[endotoxin, Escherichia coli results in increased phosphorylation of and results in increased activity of AKT1 protein] which results in increased phosphorylation of GSK3B protein]; malvidin promotes the reaction [endotoxin, Escherichia coli results in increased phosphorylation of and results in increased activity of AKT1 protein] CTD PMID:23755222 NCBI chr12:112,620,260...112,641,266
Ensembl chr12:112,620,255...112,641,318
JBrowse link
G Bax BCL2-associated X protein increases expression ISO malvidin results in increased expression of BAX protein CTD PMID:15964118 NCBI chr 7:45,111,124...45,116,332
Ensembl chr 7:45,111,121...45,116,322
JBrowse link
G Bcl2 B cell leukemia/lymphoma 2 decreases expression ISO malvidin results in decreased expression of BCL2 protein CTD PMID:15964118 NCBI chr 1:106,465,906...106,642,020
Ensembl chr 1:106,465,908...106,642,004
JBrowse link
G Casp3 caspase 3 increases activity
multiple interactions
ISO malvidin results in increased activity of CASP3 protein
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one promotes the reaction [malvidin results in increased activity of CASP3 protein]; SB 203580 inhibits the reaction [malvidin results in increased activity of CASP3 protein]
CTD PMID:15964118 NCBI chr 8:47,070,326...47,092,733
Ensembl chr 8:47,070,326...47,092,724
JBrowse link
G Dusp1 dual specificity phosphatase 1 multiple interactions EXP malvidin promotes the reaction [endotoxin, Escherichia coli results in increased expression of DUSP1 mRNA]; malvidin promotes the reaction [endotoxin, Escherichia coli results in increased expression of DUSP1 protein] CTD PMID:23755222 NCBI chr17:26,724,565...26,727,446
Ensembl chr17:26,724,564...26,781,102
JBrowse link
G Gsk3b glycogen synthase kinase 3 beta multiple interactions EXP malvidin promotes the reaction [[endotoxin, Escherichia coli results in increased phosphorylation of and results in increased activity of AKT1 protein] which results in increased phosphorylation of GSK3B protein] CTD PMID:23755222 NCBI chr16:37,909,363...38,066,446
Ensembl chr16:37,909,363...38,066,446
JBrowse link
G Mapk1 mitogen-activated protein kinase 1 decreases phosphorylation ISO malvidin results in decreased phosphorylation of MAPK1 protein CTD PMID:15964118 NCBI chr16:16,801,246...16,865,317
Ensembl chr16:16,801,246...16,865,317
JBrowse link
G Mapk14 mitogen-activated protein kinase 14 multiple interactions ISO malvidin results in increased expression of and results in increased phosphorylation of MAPK14 protein CTD PMID:15964118 NCBI chr17:28,910,316...28,967,379
Ensembl chr17:28,910,303...28,967,380
JBrowse link
G Mapk3 mitogen-activated protein kinase 3 decreases phosphorylation ISO malvidin results in decreased phosphorylation of MAPK3 protein CTD PMID:15964118 NCBI chr 7:126,358,798...126,364,988
Ensembl chr 7:126,358,773...126,364,991
JBrowse link
G Parp1 poly (ADP-ribose) polymerase family, member 1 increases cleavage ISO malvidin results in increased cleavage of PARP1 protein CTD PMID:15964118 NCBI chr 1:180,396,456...180,428,564
Ensembl chr 1:180,396,489...180,428,819
JBrowse link
G Pde5a phosphodiesterase 5A, cGMP-specific decreases activity ISO malvidin results in decreased activity of PDE5A protein CTD PMID:15769121 NCBI chr 3:122,522,822...122,653,023
Ensembl chr 3:122,522,596...122,653,023
JBrowse link
G Pdgfa platelet derived growth factor, alpha multiple interactions ISO malvidin inhibits the reaction [[PDGFA protein co-treated with PDGFB protein] results in increased abundance of Reactive Oxygen Species] CTD PMID:16921400 NCBI chr 5:138,961,761...138,986,336
Ensembl chr 5:138,961,769...138,983,125
JBrowse link
G Pdgfb platelet derived growth factor, B polypeptide multiple interactions ISO malvidin inhibits the reaction [[PDGFA protein co-treated with PDGFB protein] results in increased abundance of Reactive Oxygen Species] CTD PMID:16921400 NCBI chr15:79,880,066...79,899,178
Ensembl chr15:79,880,075...79,899,178
JBrowse link
G Rela v-rel reticuloendotheliosis viral oncogene homolog A (avian) multiple interactions EXP malvidin inhibits the reaction [endotoxin, Escherichia coli affects the localization of and results in increased phosphorylation of and results in increased activity of RELA protein] CTD PMID:23755222 NCBI chr19:5,686,993...5,698,162
Ensembl chr19:5,687,511...5,698,158
JBrowse link
malvidin 3-O-beta-D-glucoside term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aqp3 aquaporin 3 multiple interactions ISO [malvidin-3-glucoside co-treated with petunidin-3-glucoside] results in increased expression of AQP3 mRNA CTD PMID:33294640 NCBI chr 4:41,092,724...41,098,183
Ensembl chr 4:41,092,722...41,098,183
JBrowse link
G Car1 carbonic anhydrase 1 decreases activity ISO malvidin-3-glucoside results in decreased activity of CA1 protein CTD PMID:28445001 NCBI chr 3:14,831,274...14,873,425
Ensembl chr 3:14,831,276...14,873,428
JBrowse link
G Car2 carbonic anhydrase 2 decreases activity ISO malvidin-3-glucoside results in decreased activity of CA2 protein CTD PMID:28445001 NCBI chr 3:14,951,329...14,965,830
Ensembl chr 3:14,951,333...14,965,830
JBrowse link
G Nos2 nitric oxide synthase 2, inducible multiple interactions EXP malvidin-3-glucoside inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 protein] CTD PMID:23731018 NCBI chr11:78,811,613...78,851,052
Ensembl chr11:78,811,613...78,851,080
JBrowse link
G Pde5a phosphodiesterase 5A, cGMP-specific decreases activity ISO malvidin-3-glucoside results in decreased activity of PDE5A protein CTD PMID:15769121 NCBI chr 3:122,522,822...122,653,023
Ensembl chr 3:122,522,596...122,653,023
JBrowse link
G Sele selectin, endothelial cell multiple interactions ISO malvidin-3-glucoside inhibits the reaction [TNF protein results in increased expression of SELE protein] CTD PMID:30611791 NCBI chr 1:163,867,200...163,886,056
Ensembl chr 1:163,875,773...163,885,246
JBrowse link
G Tnf tumor necrosis factor multiple interactions EXP
ISO
malvidin-3-glucoside inhibits the reaction [Lipopolysaccharides results in increased expression of TNF protein]
malvidin-3-glucoside inhibits the reaction [TNF protein results in increased expression of SELE protein]
CTD PMID:23731018 PMID:30611791 NCBI chr17:35,418,343...35,420,983
Ensembl chr17:35,418,357...35,420,983
JBrowse link
malvin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Car1 carbonic anhydrase 1 decreases activity ISO malvin results in decreased activity of CA1 protein CTD PMID:28445001 NCBI chr 3:14,831,274...14,873,425
Ensembl chr 3:14,831,276...14,873,428
JBrowse link
G Car2 carbonic anhydrase 2 decreases activity ISO malvin results in decreased activity of CA2 protein CTD PMID:28445001 NCBI chr 3:14,951,329...14,965,830
Ensembl chr 3:14,951,333...14,965,830
JBrowse link
pelargonidin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ahr aryl-hydrocarbon receptor increases activity
multiple interactions
ISO pelargonidin metabolite results in increased activity of AHR protein
[pelargonidin metabolite results in increased activity of AHR protein] which results in increased expression of CYP1A1 mRNA; pelargonidin binds to and results in increased activity of AHR protein
CTD PMID:23419638 PMID:23735880 NCBI chr12:35,547,978...35,584,988
Ensembl chr12:35,547,973...35,585,037
JBrowse link
G Cdh1 cadherin 1 multiple interactions ISO pelargonidin inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of CDH1 mRNA]; pelargonidin inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of CDH1 protein] CTD PMID:30753810 NCBI chr 8:107,329,982...107,396,879
Ensembl chr 8:107,329,983...107,396,878
JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 decreases activity
increases expression
multiple interactions
ISO pelargonidin metabolite results in decreased activity of CYP1A1 protein; pelargonidin results in decreased activity of CYP1A1 protein
pelargonidin metabolite results in increased expression of CYP1A1 mRNA; pelargonidin results in increased expression of CYP1A1 mRNA
[pelargonidin metabolite results in increased activity of AHR protein] which results in increased expression of CYP1A1 mRNA; pelargonidin results in increased expression of and results in increased activity of CYP1A1 protein
CTD PMID:23419638 PMID:23735880 NCBI chr 9:57,595,211...57,611,107
Ensembl chr 9:57,595,211...57,611,107
JBrowse link
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 increases expression ISO pelargonidin results in increased expression of CYP1A2 mRNA CTD PMID:23419638 NCBI chr 9:57,584,220...57,590,938
Ensembl chr 9:57,584,220...57,590,986
JBrowse link
G Dnmt1 DNA methyltransferase 1 decreases expression EXP pelargonidin results in decreased expression of DNMT1 protein CTD PMID:31181187 NCBI chr 9:20,818,501...20,871,084
Ensembl chr 9:20,818,505...20,871,184
JBrowse link
G Dnmt3b DNA methyltransferase 3B decreases expression EXP pelargonidin results in decreased expression of DNMT3B protein CTD PMID:31181187 NCBI chr 2:153,491,332...153,529,650
Ensembl chr 2:153,491,370...153,529,650
JBrowse link
G Hdac1 histone deacetylase 1 decreases expression EXP pelargonidin results in decreased expression of HDAC1 protein CTD PMID:31181187 NCBI chr 4:129,409,897...129,436,516
Ensembl chr 4:129,409,897...129,436,506
JBrowse link
G Hdac2 histone deacetylase 2 decreases expression EXP pelargonidin results in decreased expression of HDAC2 protein CTD PMID:31181187 NCBI chr10:36,850,293...36,877,885
Ensembl chr10:36,850,540...36,877,885
JBrowse link
G Hdac3 histone deacetylase 3 decreases expression EXP pelargonidin results in decreased expression of HDAC3 protein CTD PMID:31181187 NCBI chr18:38,070,024...38,088,073
Ensembl chr18:38,068,897...38,088,069
JBrowse link
G Hdac4 histone deacetylase 4 decreases expression EXP pelargonidin results in decreased expression of HDAC4 protein CTD PMID:31181187 NCBI chr 1:91,856,501...92,123,424
Ensembl chr 1:91,856,501...92,123,421
JBrowse link
G Hdac7 histone deacetylase 7 decreases expression EXP pelargonidin results in decreased expression of HDAC7 protein CTD PMID:31181187 NCBI chr15:97,690,542...97,742,383
Ensembl chr15:97,690,545...97,742,383
JBrowse link
G Hmox1 heme oxygenase 1 increases expression EXP pelargonidin results in increased expression of HMOX1 mRNA; pelargonidin results in increased expression of HMOX1 protein CTD PMID:31181187 NCBI chr 8:75,820,246...75,827,221
Ensembl chr 8:75,820,249...75,827,217
JBrowse link
G Icam1 intercellular adhesion molecule 1 multiple interactions ISO pelargonidin inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of ICAM1 mRNA]; pelargonidin inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of ICAM1 protein] CTD PMID:30753810 NCBI chr 9:20,927,236...20,940,110
Ensembl chr 9:20,927,281...20,940,113
JBrowse link
G Il6 interleukin 6 multiple interactions ISO pelargonidin inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased secretion of IL6 protein] CTD PMID:30753810 NCBI chr 5:30,218,112...30,224,973
Ensembl chr 5:30,218,112...30,224,979
JBrowse link
G Mapk1 mitogen-activated protein kinase 1 multiple interactions ISO pelargonidin inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased phosphorylation of MAPK1 protein] CTD PMID:30753810 NCBI chr16:16,801,246...16,865,317
Ensembl chr16:16,801,246...16,865,317
JBrowse link
G Mapk3 mitogen-activated protein kinase 3 multiple interactions ISO pelargonidin inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased phosphorylation of MAPK3 protein] CTD PMID:30753810 NCBI chr 7:126,358,798...126,364,988
Ensembl chr 7:126,358,773...126,364,991
JBrowse link
G Nfe2l2 nuclear factor, erythroid derived 2, like 2 decreases methylation
affects response to substance
EXP pelargonidin results in decreased methylation of NFE2L2 promoter
NFE2L2 protein affects the susceptibility to pelargonidin
CTD PMID:31181187 NCBI chr 2:75,505,860...75,535,007
Ensembl chr 2:75,505,857...75,534,985
JBrowse link
G Nos2 nitric oxide synthase 2, inducible multiple interactions EXP pelargonidin inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 mRNA]; pelargonidin inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 protein] CTD PMID:18274639 NCBI chr11:78,811,613...78,851,052
Ensembl chr11:78,811,613...78,851,080
JBrowse link
G Nqo1 NAD(P)H dehydrogenase, quinone 1 increases expression EXP pelargonidin results in increased expression of NQO1 mRNA; pelargonidin results in increased expression of NQO1 protein CTD PMID:31181187 NCBI chr 8:108,114,856...108,139,012
Ensembl chr 8:108,114,857...108,129,838
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 multiple interactions EXP pelargonidin inhibits the reaction [Lipopolysaccharides results in increased expression of PTGS2 mRNA] CTD PMID:21341175 NCBI chr 1:149,975,851...149,983,978
Ensembl chr 1:149,975,782...149,983,978
JBrowse link
G Rela v-rel reticuloendotheliosis viral oncogene homolog A (avian) multiple interactions EXP
ISO
pelargonidin inhibits the reaction [Lipopolysaccharides affects the localization of and results in increased activity of RELA protein]
pelargonidin inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased phosphorylation of RELA protein]
CTD PMID:18274639 PMID:30753810 NCBI chr19:5,686,993...5,698,162
Ensembl chr19:5,687,511...5,698,158
JBrowse link
G Tlr4 toll-like receptor 4 multiple interactions ISO pelargonidin inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of TLR4 protein] CTD PMID:30753810 NCBI chr 4:66,745,788...66,765,338
Ensembl chr 4:66,745,821...66,848,521
JBrowse link
G Tnf tumor necrosis factor multiple interactions EXP
ISO
pelargonidin inhibits the reaction [Lipopolysaccharides results in increased expression of TNF]
pelargonidin inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased secretion of TNF protein]
CTD PMID:18720166 PMID:30753810 NCBI chr17:35,418,343...35,420,983
Ensembl chr17:35,418,357...35,420,983
JBrowse link
G Txnrd1 thioredoxin reductase 1 decreases activity ISO pelargonidin results in decreased activity of TXNRD1 protein modified form CTD PMID:16618767 NCBI chr10:82,669,785...82,733,558
Ensembl chr10:82,669,785...82,733,546
JBrowse link
G Vcam1 vascular cell adhesion molecule 1 multiple interactions ISO pelargonidin inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of VCAM1 mRNA]; pelargonidin inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of VCAM1 protein] CTD PMID:30753810 NCBI chr 3:115,903,669...115,923,337
Ensembl chr 3:115,903,598...115,923,337
JBrowse link
pelargonidin 3-O-beta-D-glucoside term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Car1 carbonic anhydrase 1 decreases activity ISO pelargonidin-3-glucoside results in decreased activity of CA1 protein CTD PMID:28445001 NCBI chr 3:14,831,274...14,873,425
Ensembl chr 3:14,831,276...14,873,428
JBrowse link
G Car2 carbonic anhydrase 2 decreases activity ISO pelargonidin-3-glucoside results in decreased activity of CA2 protein CTD PMID:28445001 NCBI chr 3:14,951,329...14,965,830
Ensembl chr 3:14,951,333...14,965,830
JBrowse link
pelargonidin 3-O-beta-D-glucoside chloride term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Car1 carbonic anhydrase 1 decreases activity ISO pelargonidin-3-glucoside results in decreased activity of CA1 protein CTD PMID:28445001 NCBI chr 3:14,831,274...14,873,425
Ensembl chr 3:14,831,276...14,873,428
JBrowse link
G Car2 carbonic anhydrase 2 decreases activity ISO pelargonidin-3-glucoside results in decreased activity of CA2 protein CTD PMID:28445001 NCBI chr 3:14,951,329...14,965,830
Ensembl chr 3:14,951,333...14,965,830
JBrowse link
peonidin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pdgfa platelet derived growth factor, alpha multiple interactions ISO peonidin inhibits the reaction [[PDGFA protein co-treated with PDGFB protein] results in increased abundance of Reactive Oxygen Species] CTD PMID:16921400 NCBI chr 5:138,961,761...138,986,336
Ensembl chr 5:138,961,769...138,983,125
JBrowse link
G Pdgfb platelet derived growth factor, B polypeptide multiple interactions ISO peonidin inhibits the reaction [[PDGFA protein co-treated with PDGFB protein] results in increased abundance of Reactive Oxygen Species] CTD PMID:16921400 NCBI chr15:79,880,066...79,899,178
Ensembl chr15:79,880,075...79,899,178
JBrowse link
peonidin chloride term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pdgfa platelet derived growth factor, alpha multiple interactions ISO peonidin inhibits the reaction [[PDGFA protein co-treated with PDGFB protein] results in increased abundance of Reactive Oxygen Species] CTD PMID:16921400 NCBI chr 5:138,961,761...138,986,336
Ensembl chr 5:138,961,769...138,983,125
JBrowse link
G Pdgfb platelet derived growth factor, B polypeptide multiple interactions ISO peonidin inhibits the reaction [[PDGFA protein co-treated with PDGFB protein] results in increased abundance of Reactive Oxygen Species] CTD PMID:16921400 NCBI chr15:79,880,066...79,899,178
Ensembl chr15:79,880,075...79,899,178
JBrowse link
petunidin 3-O-beta-D-glucoside term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aqp3 aquaporin 3 multiple interactions ISO [malvidin-3-glucoside co-treated with petunidin-3-glucoside] results in increased expression of AQP3 mRNA CTD PMID:33294640 NCBI chr 4:41,092,724...41,098,183
Ensembl chr 4:41,092,722...41,098,183
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 22178
    chemical entity 22208
      molecular entity 22169
        ion 17696
          organic ion 10063
            organic cation 9099
              anthocyanidin cation 135
                3-hydroxy-2-phenylchromenylium 0
                3-hydroxyanthocyanidin cation 0
                5-hydroxyanthocyanidin + 88
                anthocyanidin + 2
                anthocyanidin glycoside + 2
                anthocyanin cation + 71
                capensinidin 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 22178
    subatomic particle 22170
      composite particle 22170
        hadron 22201
          baryon 22170
            nucleon 22170
              atomic nucleus 22170
                atom 22170
                  main group element atom 22104
                    p-block element atom 22104
                      carbon group element atom 21904
                        carbon atom 21859
                          organic molecular entity 21830
                            organic molecule 21647
                              organic cyclic compound 21252
                                organic heterocyclic compound 20352
                                  oxacycle 18822
                                    benzopyran 12194
                                      1-benzopyran 11952
                                        chromenes 4421
                                          chromene 135
                                            2H-chromene 135
                                              chromenyliums 135
                                                chromenylium 135
                                                  flavylium 135
                                                    anthocyanidin cation 135
                                                      3-hydroxy-2-phenylchromenylium 0
                                                      3-hydroxyanthocyanidin cation 0
                                                      5-hydroxyanthocyanidin + 88
                                                      anthocyanidin + 2
                                                      anthocyanidin glycoside + 2
                                                      anthocyanin cation + 71
                                                      capensinidin 0
paths to the root