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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:anthocyanidin cation
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Accession:CHEBI:16366 term browser browse the term
Definition:Any organic cation that is an aglycon of anthocyanin cation; they are oxygenated derivatives of flavylium (2-phenylchromenylium).
Synonyms:exact_synonym: anthocyanidins
 related_synonym: Anthocyanidin;   Formula=C15OR11;   SMILES=[*]c1c([*])c([*])c(c([*])c1[*])-c1[o+]c2c([*])c([*])c([*])c([*])c2c([*])c1[*];   anthocyanidin cations
 alt_id: CHEBI:13837;   CHEBI:22572;   CHEBI:2751
 xref: HMDB:HMDB0031460;   KEGG:C02003;   MetaCyc:Anthocyanidins;   Wikipedia:Anthocyanidins


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anthocyanin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acta2 actin alpha 2, smooth muscle multiple interactions
decreases expression
ISO
EXP
Anthocyanins inhibits the reaction [Carbon Tetrachloride results in increased expression of ACTA2 protein]
Anthocyanins inhibits the reaction [Paraquat results in increased expression of ACTA2 mRNA]; Anthocyanins inhibits the reaction [Paraquat results in increased expression of ACTA2 protein]
Anthocyanins results in decreased expression of ACTA2 mRNA; Anthocyanins results in decreased expression of ACTA2 protein
CTD PMID:30056145, PMID:30403199 NCBI chr 1:252,537,614...252,550,394
Ensembl chr 1:252,537,615...252,550,394
JBrowse link
G Ager advanced glycosylation end product-specific receptor multiple interactions ISO Anthocyanins inhibits the reaction [Dietary Fats results in increased expression of AGER protein] CTD PMID:24795233 NCBI chr20:4,363,152...4,366,079
Ensembl chr20:4,363,152...4,366,079
JBrowse link
G Atm ATM serine/threonine kinase increases phosphorylation ISO Anthocyanins results in increased phosphorylation of ATM protein CTD PMID:27444805 NCBI chr 8:58,015,938...58,119,973
Ensembl chr 8:58,015,940...58,120,045
JBrowse link
G B2m beta-2 microglobulin multiple interactions EXP Anthocyanins inhibits the reaction [Carbon Tetrachloride results in increased expression of B2M protein] CTD PMID:30825423 NCBI chr 3:114,087,287...114,093,311
Ensembl chr 3:114,087,287...114,093,309
JBrowse link
G Bad BCL2-associated agonist of cell death multiple interactions EXP Anthocyanins inhibits the reaction [Streptozocin results in decreased expression of BAD protein modified form]; Anthocyanins inhibits the reaction [Streptozocin results in increased expression of BAD protein] CTD PMID:28856781 NCBI chr 1:222,198,516...222,207,459
Ensembl chr 1:222,198,534...222,207,453
JBrowse link
G Bak1 BCL2-antagonist/killer 1 multiple interactions EXP Anthocyanins inhibits the reaction [Streptozocin results in increased expression of BAK1 protein] CTD PMID:28856781 NCBI chr20:5,609,620...5,618,899
Ensembl chr20:5,609,625...5,618,260
JBrowse link
G Bax BCL2 associated X, apoptosis regulator multiple interactions EXP Anthocyanins inhibits the reaction [Paraquat results in increased expression of BAX mRNA]; Anthocyanins inhibits the reaction [Paraquat results in increased expression of BAX protein] CTD PMID:30403199 NCBI chr 1:101,451,801...101,457,207
Ensembl chr 1:101,451,802...101,457,207
JBrowse link
G Bcl2 BCL2, apoptosis regulator multiple interactions EXP Anthocyanins inhibits the reaction [Paraquat results in decreased expression of BCL2 mRNA]; Anthocyanins inhibits the reaction [Paraquat results in decreased expression of BCL2 protein]; Anthocyanins inhibits the reaction [Streptozocin results in decreased expression of BCL2 protein] CTD PMID:28856781, PMID:30403199 NCBI chr13:26,605,426...26,769,374
Ensembl chr13:26,605,426...26,769,374
JBrowse link
G Bcl2l1 Bcl2-like 1 multiple interactions EXP Anthocyanins inhibits the reaction [Streptozocin results in decreased expression of BCL2L1 protein] CTD PMID:28856781 NCBI chr 3:148,259,594...148,314,191
Ensembl chr 3:148,259,596...148,313,810
JBrowse link
G Car1 carbonic anhydrase 1 decreases activity ISO Anthocyanins results in decreased activity of CA1 protein CTD PMID:28445001 NCBI chr 2:88,185,204...88,227,486
Ensembl chr 2:88,217,188...88,227,479
JBrowse link
G Car2 carbonic anhydrase 2 decreases activity ISO Anthocyanins results in decreased activity of CA2 protein CTD PMID:28445001 NCBI chr 2:88,097,740...88,112,868
Ensembl chr 2:88,097,720...88,113,029
JBrowse link
G Casp1 caspase 1 multiple interactions ISO Anthocyanins inhibits the reaction [Dietary Fats results in increased activity of CASP1 protein] CTD PMID:24795233 NCBI chr 8:2,605,743...2,614,637
Ensembl chr 8:2,604,962...2,614,631
JBrowse link
G Casp3 caspase 3 multiple interactions EXP Anthocyanins inhibits the reaction [Streptozocin results in increased cleavage of CASP3 protein] CTD PMID:28856781 NCBI chr16:48,845,011...48,863,249
Ensembl chr16:48,845,012...48,863,204
JBrowse link
G Casp8 caspase 8 multiple interactions EXP Anthocyanins inhibits the reaction [Streptozocin results in increased expression of CASP8 protein] CTD PMID:28856781 NCBI chr 9:65,614,142...65,662,624
Ensembl chr 9:65,614,142...65,662,106
JBrowse link
G Casp9 caspase 9 multiple interactions EXP Anthocyanins inhibits the reaction [Streptozocin results in increased expression of CASP9 protein] CTD PMID:28856781 NCBI chr 5:160,356,211...160,373,774
Ensembl chr 5:160,355,833...160,373,778
JBrowse link
G Cat catalase multiple interactions EXP Anthocyanins inhibits the reaction [Carbon Tetrachloride results in decreased activity of CAT protein] CTD PMID:30825423 NCBI chr 3:93,379,872...93,412,058
Ensembl chr 3:93,379,874...93,412,058
JBrowse link
G Ccl2 C-C motif chemokine ligand 2 multiple interactions ISO Anthocyanins inhibits the reaction [Carbon Tetrachloride results in increased expression of CCL2 protein] CTD PMID:30056145 NCBI chr10:69,412,065...69,413,863
Ensembl chr10:69,412,017...69,413,870
JBrowse link
G Ccn2 cellular communication network factor 2 decreases expression ISO Anthocyanins results in decreased expression of CCN2 mRNA CTD PMID:30056145 NCBI chr 1:21,851,657...21,854,773
Ensembl chr 1:21,851,660...21,854,773
JBrowse link
G Ccnb1 cyclin B1 increases expression
multiple interactions
ISO Anthocyanins results in increased expression of CCNB1 protein
Anthocyanins promotes the reaction [CDK1 protein binds to CCNB1 protein]
CTD PMID:27444805 NCBI chr 2:30,782,133...30,791,106
Ensembl chr 2:30,783,915...30,791,221
JBrowse link
G Cdc25c cell division cycle 25C multiple interactions
increases phosphorylation
ISO Anthocyanins results in decreased expression of and results in increased phosphorylation of CDC25C protein
Anthocyanins results in increased phosphorylation of CDC25C protein
CTD PMID:27444805 NCBI chr18:27,528,768...27,550,316
Ensembl chr18:27,528,354...27,550,224
JBrowse link
G Cdh1 cadherin 1 multiple interactions EXP Anthocyanins inhibits the reaction [Paraquat results in decreased expression of CDH1 protein] CTD PMID:30403199 NCBI chr19:38,768,467...38,838,395
Ensembl chr19:38,768,467...38,838,395
JBrowse link
G Cdk1 cyclin-dependent kinase 1 multiple interactions ISO Anthocyanins promotes the reaction [CDK1 protein binds to CCNB1 protein]; Anthocyanins results in increased expression of and results in increased phosphorylation of CDK1 protein CTD PMID:27444805 NCBI chr20:20,576,341...20,591,510
Ensembl chr20:20,576,377...20,591,549
JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A increases expression ISO Anthocyanins results in increased expression of CDKN1A protein CTD PMID:27444805 NCBI chr20:6,348,422...6,358,864
Ensembl chr20:6,351,458...6,358,864
JBrowse link
G Cdkn1b cyclin-dependent kinase inhibitor 1B increases expression ISO Anthocyanins results in increased expression of CDKN1B protein CTD PMID:27444805 NCBI chr 4:168,689,043...168,694,159
Ensembl chr 4:168,689,163...168,693,964
JBrowse link
G Chek1 checkpoint kinase 1 increases phosphorylation ISO Anthocyanins results in increased phosphorylation of CHEK1 protein CTD PMID:27444805 NCBI chr 8:39,181,162...39,201,588
Ensembl chr 8:39,181,163...39,243,882
JBrowse link
G Chek2 checkpoint kinase 2 increases phosphorylation ISO Anthocyanins results in increased phosphorylation of CHEK2 protein CTD PMID:27444805 NCBI chr12:51,845,574...51,878,098
Ensembl chr12:51,845,796...51,877,624
JBrowse link
G Cldn4 claudin 4 multiple interactions EXP Anthocyanins inhibits the reaction [Cyclophosphamide results in decreased expression of CLDN4 protein] CTD PMID:25451569 NCBI chr12:24,761,210...24,763,008
Ensembl chr12:24,761,210...24,763,005
JBrowse link
G Col1a1 collagen type I alpha 1 chain multiple interactions EXP Anthocyanins inhibits the reaction [Paraquat results in increased expression of COL1A1 mRNA] CTD PMID:30403199 NCBI chr10:82,745,801...82,762,790
Ensembl chr10:82,745,801...82,762,789
JBrowse link
G Col3a1 collagen type III alpha 1 chain multiple interactions ISO Anthocyanins inhibits the reaction [Carbon Tetrachloride results in increased expression of COL3A1 protein] CTD PMID:30056145 NCBI chr 9:52,023,295...52,059,221
Ensembl chr 9:52,023,295...52,059,217
JBrowse link
G Ctsd cathepsin D multiple interactions EXP Anthocyanins inhibits the reaction [Cyclophosphamide results in increased activity of CTSD protein] CTD PMID:25451569 NCBI chr 1:215,541,570...215,553,446
Ensembl chr 1:215,541,542...215,553,451
JBrowse link
G Cxcl2 C-X-C motif chemokine ligand 2 multiple interactions ISO Anthocyanins inhibits the reaction [Carbon Tetrachloride results in increased expression of CXCL2] CTD PMID:30056145 NCBI chr14:18,731,346...18,733,391
Ensembl chr14:18,731,378...18,733,391
JBrowse link
G Cyp2c11 cytochrome P450, subfamily 2, polypeptide 11 increases expression EXP Anthocyanins results in increased expression of CYP2C mRNA CTD PMID:18803703 NCBI chr 1:257,676,172...258,004,428
Ensembl chr 1:257,970,345...258,004,434
JBrowse link
G Cyp2e1 cytochrome P450, family 2, subfamily e, polypeptide 1 increases expression EXP Anthocyanins results in increased expression of CYP2E1 mRNA CTD PMID:18803703 NCBI chr 1:213,511,892...213,522,195
Ensembl chr 1:213,511,874...213,535,542
JBrowse link
G Cyp3a2 cytochrome P450, family 3, subfamily a, polypeptide 2 increases expression EXP Anthocyanins results in increased expression of CYP3A2 mRNA CTD PMID:18803703 NCBI chr12:11,641,500...11,677,818
Ensembl chr12:11,655,402...11,733,136
JBrowse link
G Cyp3a23-3a1 cytochrome P450, family 3, subfamily a, polypeptide 23-polypeptide 1 increases expression EXP Anthocyanins results in increased expression of CYP3A23-3A1 mRNA CTD PMID:18803703 NCBI chr12:11,053,888...11,082,742
Ensembl chr12:11,655,402...11,733,136
JBrowse link
G Fadd Fas associated via death domain multiple interactions EXP Anthocyanins inhibits the reaction [Streptozocin results in increased expression of FADD protein] CTD PMID:28856781 NCBI chr 1:217,746,176...217,748,581
Ensembl chr 1:217,742,929...217,748,628
JBrowse link
G Fas Fas cell surface death receptor multiple interactions EXP Anthocyanins inhibits the reaction [Streptozocin results in increased expression of FAS protein] CTD PMID:28856781 NCBI chr 1:252,589,785...252,624,790
Ensembl chr 1:252,589,785...252,624,790
JBrowse link
G Faslg Fas ligand multiple interactions EXP Anthocyanins inhibits the reaction [Streptozocin results in increased expression of FASLG protein] CTD PMID:28856781 NCBI chr13:79,696,811...79,717,581
Ensembl chr13:79,698,445...79,705,705
JBrowse link
G Gsr glutathione-disulfide reductase multiple interactions EXP Anthocyanins inhibits the reaction [Carbon Tetrachloride results in decreased activity of GSR protein] CTD PMID:30825423 NCBI chr16:62,197,617...62,239,987
Ensembl chr16:62,197,617...62,241,361
JBrowse link
G Gusb glucuronidase, beta multiple interactions EXP Anthocyanins inhibits the reaction [Cyclophosphamide results in increased activity of GUSB protein] CTD PMID:25451569 NCBI chr12:30,202,066...30,215,583
Ensembl chr12:30,198,822...30,227,771
JBrowse link
G H2ax H2A.X variant histone increases phosphorylation ISO Anthocyanins results in increased phosphorylation of H2AX protein CTD PMID:27444805 NCBI chr 8:48,665,652...48,666,981
Ensembl chr 8:48,665,652...48,666,981
JBrowse link
G Havcr1 hepatitis A virus cellular receptor 1 multiple interactions EXP Anthocyanins inhibits the reaction [Carbon Tetrachloride results in increased expression of HAVCR1 protein] CTD PMID:30825423 NCBI chr10:31,813,819...31,860,934
Ensembl chr10:31,813,814...31,848,379
JBrowse link
G Ikbkb inhibitor of nuclear factor kappa B kinase subunit beta multiple interactions ISO Anthocyanins inhibits the reaction [Dietary Fats results in increased phosphorylation of IKBKB protein] CTD PMID:24795233 NCBI chr16:74,177,233...74,230,809
Ensembl chr16:74,177,215...74,230,815
JBrowse link
G Il10 interleukin 10 multiple interactions EXP Anthocyanins inhibits the reaction [Cyclophosphamide results in decreased expression of IL10 protein] CTD PMID:25451569 NCBI chr13:47,738,933...47,743,392
Ensembl chr13:47,739,526...47,743,392
JBrowse link
G Il1b interleukin 1 beta multiple interactions EXP
ISO
Anthocyanins inhibits the reaction [Cyclophosphamide results in increased expression of IL1B protein]
Anthocyanins inhibits the reaction [Carbon Tetrachloride results in increased expression of IL1B protein]; Anthocyanins inhibits the reaction [Dietary Fats results in increased expression of IL1B protein]
CTD PMID:24795233, PMID:25451569, PMID:30056145 NCBI chr 3:121,876,256...121,882,637
Ensembl chr 3:121,876,263...121,882,726
JBrowse link
G Lcn2 lipocalin 2 multiple interactions EXP Anthocyanins inhibits the reaction [Carbon Tetrachloride results in increased expression of LCN2 protein] CTD PMID:30825423 NCBI chr 3:11,414,189...11,417,534
Ensembl chr 3:11,414,186...11,417,546
JBrowse link
G Mmp9 matrix metallopeptidase 9 multiple interactions ISO Anthocyanins inhibits the reaction [Carbon Tetrachloride results in decreased expression of MMP9 protein] CTD PMID:30056145 NCBI chr 3:161,413,410...161,421,473
Ensembl chr 3:161,413,298...161,421,520
JBrowse link
G Mpo myeloperoxidase multiple interactions EXP Anthocyanins inhibits the reaction [Carbon Tetrachloride results in increased activity of MPO protein]; Anthocyanins inhibits the reaction [Cyclophosphamide results in increased activity of MPO protein] CTD PMID:25451569, PMID:30825423 NCBI chr10:75,087,892...75,098,260
Ensembl chr10:75,087,892...75,098,260
JBrowse link
G Nfkbia NFKB inhibitor alpha multiple interactions ISO Anthocyanins inhibits the reaction [Dietary Fats results in increased degradation of NFKBIA protein] CTD PMID:24795233 NCBI chr 6:76,267,227...76,270,457
Ensembl chr 6:76,267,228...76,270,457
JBrowse link
G Nlrp3 NLR family, pyrin domain containing 3 multiple interactions ISO Anthocyanins inhibits the reaction [Dietary Fats results in increased expression of NLRP3 protein] CTD PMID:24795233 NCBI chr10:45,884,324...45,918,290
Ensembl chr10:45,893,018...45,918,254
JBrowse link
G Nos2 nitric oxide synthase 2 multiple interactions ISO Anthocyanins inhibits the reaction [Dietary Fats results in increased expression of NOS2 protein] CTD PMID:24795233 NCBI chr10:66,188,290...66,221,621
Ensembl chr10:66,189,786...66,313,190
JBrowse link
G Parp1 poly (ADP-ribose) polymerase 1 multiple interactions EXP Anthocyanins inhibits the reaction [Streptozocin results in increased cleavage of PARP1 protein] CTD PMID:28856781 NCBI chr13:98,857,255...98,889,444
Ensembl chr13:98,857,177...98,889,716
JBrowse link
G Pcna proliferating cell nuclear antigen multiple interactions ISO Anthocyanins inhibits the reaction [Carbon Tetrachloride results in increased expression of PCNA protein] CTD PMID:30056145 NCBI chr 3:124,880,698...124,884,570
Ensembl chr 3:124,880,698...124,884,570
JBrowse link
G Pde5a phosphodiesterase 5A decreases activity ISO Anthocyanins results in decreased activity of PDE5A protein CTD PMID:15769121 NCBI chr 2:226,899,604...227,044,916
Ensembl chr 2:226,900,619...227,041,576
JBrowse link
G Pik3r1 phosphoinositide-3-kinase regulatory subunit 1 increases expression EXP Anthocyanins results in increased expression of PIK3R1 mRNA CTD PMID:18803703 NCBI chr 2:31,742,326...31,826,882
Ensembl chr 2:31,745,088...31,826,867
JBrowse link
G Pla2g2a phospholipase A2 group IIA increases expression EXP Anthocyanins results in increased expression of PLA2G2A mRNA CTD PMID:18803703 NCBI chr 5:157,282,650...157,285,295
Ensembl chr 5:157,282,669...157,285,328
JBrowse link
G Plcd4 phospholipase C, delta 4 increases expression EXP Anthocyanins results in increased expression of PLCD4 mRNA CTD PMID:18803703 NCBI chr 9:81,816,395...81,844,364
Ensembl chr 9:81,816,872...81,844,364
JBrowse link
G Por cytochrome p450 oxidoreductase increases expression EXP Anthocyanins results in increased expression of POR mRNA CTD PMID:18803703 NCBI chr12:23,998,411...24,017,063
Ensembl chr12:23,998,411...24,046,814
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 multiple interactions ISO Anthocyanins inhibits the reaction [Dietary Fats results in increased expression of PTGS2 protein] CTD PMID:24795233 NCBI chr13:67,351,230...67,356,920
Ensembl chr13:67,351,087...67,359,335
JBrowse link
G Pycard PYD and CARD domain containing multiple interactions ISO Anthocyanins inhibits the reaction [Dietary Fats results in increased expression of PYCARD protein] CTD PMID:24795233 NCBI chr 1:199,438,029...199,439,062
Ensembl chr 1:199,437,832...199,439,210
JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit multiple interactions EXP Anthocyanins inhibits the reaction [Cyclophosphamide results in increased activity of RELA protein] CTD PMID:25451569 NCBI chr 1:220,992,770...221,003,249
Ensembl chr 1:220,992,770...221,003,249
JBrowse link
G Smad2 SMAD family member 2 multiple interactions EXP Anthocyanins inhibits the reaction [Paraquat results in increased phosphorylation of SMAD2 protein] CTD PMID:30403199 NCBI chr18:72,550,107...72,612,078
Ensembl chr18:72,550,219...72,612,078
JBrowse link
G Snca synuclein alpha decreases expression ISO Anthocyanins results in decreased expression of SNCA protein CTD PMID:29976995 NCBI chr 4:90,782,412...90,883,236
Ensembl chr 4:90,782,374...90,882,285
JBrowse link
G Tgfb1 transforming growth factor, beta 1 decreases expression
multiple interactions
ISO
EXP
Anthocyanins results in decreased expression of TGFB1 mRNA
Anthocyanins inhibits the reaction [Paraquat results in increased expression of TGFB1 protein]
CTD PMID:30056145, PMID:30403199 NCBI chr 1:82,480,875...82,497,196
Ensembl chr 1:82,480,195...82,497,199
JBrowse link
G Tgfbr1 transforming growth factor, beta receptor 1 multiple interactions EXP Anthocyanins inhibits the reaction [Paraquat results in increased expression of TGFBR1 protein] CTD PMID:30403199 NCBI chr 5:63,056,071...63,119,635
Ensembl chr 5:63,050,758...63,119,635
JBrowse link
G Timp1 TIMP metallopeptidase inhibitor 1 multiple interactions ISO Anthocyanins inhibits the reaction [Carbon Tetrachloride results in increased expression of TIMP1 protein] CTD PMID:30056145 NCBI chr  X:1,364,771...1,369,451
Ensembl chr  X:1,364,786...1,369,384
JBrowse link
G Tjp1 tight junction protein 1 multiple interactions EXP Anthocyanins inhibits the reaction [Cyclophosphamide results in decreased expression of TJP1 protein] CTD PMID:25451569 NCBI chr 1:126,146,489...126,515,359
Ensembl chr 1:126,146,489...126,227,469
JBrowse link
G Tnf tumor necrosis factor multiple interactions EXP
ISO
Anthocyanins inhibits the reaction [Carbon Tetrachloride results in increased expression of TNF protein]; Anthocyanins inhibits the reaction [Cyclophosphamide results in increased expression of TNF protein]
Anthocyanins inhibits the reaction [Lipopolysaccharides results in increased expression of TNF]
CTD PMID:18720166, PMID:25451569, PMID:30825423 NCBI chr20:5,189,382...5,192,000
Ensembl chr20:5,189,390...5,192,000
JBrowse link
G Txnip thioredoxin interacting protein multiple interactions ISO Anthocyanins inhibits the reaction [Dietary Fats results in increased expression of TXNIP protein] CTD PMID:24795233 NCBI chr 2:198,683,168...198,686,971
Ensembl chr 2:198,683,159...198,686,974
JBrowse link
G Vim vimentin multiple interactions EXP Anthocyanins inhibits the reaction [Paraquat results in increased expression of VIM mRNA]; Anthocyanins inhibits the reaction [Paraquat results in increased expression of VIM protein] CTD PMID:30403199 NCBI chr17:80,882,715...80,891,200
Ensembl chr17:80,882,666...80,891,212
JBrowse link
G Xdh xanthine dehydrogenase multiple interactions EXP Anthocyanins inhibits the reaction [Carbon Tetrachloride results in increased activity of XDH protein] CTD PMID:30825423 NCBI chr 6:25,149,570...25,211,273
Ensembl chr 6:25,149,235...25,211,494
JBrowse link
cyanidin 3-O-beta-D-glucoside term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Agt angiotensinogen multiple interactions ISO 4-methyl-N1-(3-phenylpropyl)benzene-1,2-diamine inhibits the reaction [cyanidin 3-O-glucoside inhibits the reaction [AGT protein results in increased expression of NOS2 protein]]; cyanidin 3-O-glucoside inhibits the reaction [AGT protein results in decreased expression of HMOX1 protein]; cyanidin 3-O-glucoside inhibits the reaction [AGT protein results in increased degradation of NFKBIA protein]; cyanidin 3-O-glucoside inhibits the reaction [AGT protein results in increased expression of and affects the localization of RELA protein]; cyanidin 3-O-glucoside inhibits the reaction [AGT protein results in increased expression of NOS2 protein] CTD PMID:27983965 NCBI chr19:57,321,594...57,333,460
Ensembl chr19:57,321,640...57,333,433
JBrowse link
G Ahr aryl hydrocarbon receptor multiple interactions
increases activity
ISO [cyanidin 3-O-glucoside results in increased activity of AHR protein] which results in increased expression of CYP1A1 mRNA CTD PMID:23735880 NCBI chr 6:54,963,990...55,001,806
Ensembl chr 6:54,963,990...55,001,464
JBrowse link
G Akt1 AKT serine/threonine kinase 1 multiple interactions ISO cyanidin 3-O-glucoside inhibits the reaction [7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide results in increased phosphorylation of AKT1 protein] CTD PMID:21501596 NCBI chr 6:137,218,398...137,239,970
Ensembl chr 6:137,218,376...137,236,258
JBrowse link
G Akt2 AKT serine/threonine kinase 2 increases expression ISO cyanidin 3-O-glucoside results in increased expression of AKT2 mRNA CTD PMID:30597948 NCBI chr 1:84,400,939...84,451,223
Ensembl chr 1:84,411,726...84,450,162
JBrowse link
G Avp arginine vasopressin multiple interactions ISO cyanidin 3-O-glucoside inhibits the reaction [Cadmium Chloride results in increased expression of AVP mRNA] CTD PMID:31014900 NCBI chr 3:123,117,482...123,119,460
Ensembl chr 3:123,117,492...123,119,460
JBrowse link
G Casp3 caspase 3 multiple interactions
increases expression
ISO cyanidin 3-O-glucoside inhibits the reaction [Oxygen deficiency results in increased activity of CASP3 protein]
cyanidin 3-O-glucoside results in increased expression of CASP3 mRNA
CTD PMID:24518827, PMID:30597948 NCBI chr16:48,845,011...48,863,249
Ensembl chr16:48,845,012...48,863,204
JBrowse link
G Casp8 caspase 8 increases expression ISO cyanidin 3-O-glucoside results in increased expression of CASP8 mRNA CTD PMID:30597948 NCBI chr 9:65,614,142...65,662,624
Ensembl chr 9:65,614,142...65,662,106
JBrowse link
G Crem cAMP responsive element modulator multiple interactions ISO cyanidin 3-O-glucoside inhibits the reaction [Cadmium Chloride results in decreased expression of CREM protein] CTD PMID:31014900 NCBI chr17:57,021,704...57,090,888
Ensembl chr17:57,031,766...57,090,888
JBrowse link
G Cyp11a1 cytochrome P450, family 11, subfamily a, polypeptide 1 multiple interactions ISO cyanidin 3-O-glucoside inhibits the reaction [Cadmium Chloride results in decreased expression of CYP11A1 protein] CTD PMID:31014900 NCBI chr 8:62,798,317...62,809,848
Ensembl chr 8:62,779,875...62,809,893
JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 decreases activity
increases expression
multiple interactions
ISO cyanidin 3-O-glucoside results in decreased activity of CYP1A1 protein
cyanidin 3-O-glucoside results in increased expression of CYP1A1 mRNA
[cyanidin 3-O-glucoside results in increased activity of AHR protein] which results in increased expression of CYP1A1 mRNA
CTD PMID:23735880 NCBI chr 8:62,472,087...62,478,122
Ensembl chr 8:62,472,095...62,478,147
JBrowse link
G Fshb follicle stimulating hormone subunit beta multiple interactions ISO cyanidin 3-O-glucoside inhibits the reaction [Cadmium Chloride results in increased secretion of FSHB protein] CTD PMID:31014900 NCBI chr 3:98,088,321...98,092,131
Ensembl chr 3:98,088,324...98,092,131
JBrowse link
G Fshr follicle stimulating hormone receptor multiple interactions ISO cyanidin 3-O-glucoside inhibits the reaction [Cadmium Chloride results in decreased expression of FSHR mRNA] CTD PMID:31014900 NCBI chr 6:12,796,383...12,997,817
Ensembl chr 6:12,796,383...12,997,817
JBrowse link
G Fyn FYN proto-oncogene, Src family tyrosine kinase multiple interactions
affects binding
ISO [cyanidin 3-O-glucoside binds to FYN protein] which results in decreased activity of FYN protein; cyanidin 3-O-glucoside inhibits the reaction [7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide results in increased activity of FYN protein] CTD PMID:21501596 NCBI chr20:44,436,354...44,630,316
Ensembl chr20:44,436,403...44,630,317
JBrowse link
G Gclc glutamate-cysteine ligase, catalytic subunit multiple interactions ISO [IL1A protein co-treated with TNF protein co-treated with IFNG protein co-treated with cyanidin 3-O-glucoside] results in increased expression of GCLC mRNA CTD PMID:27818126 NCBI chr 8:85,059,051...85,097,471
Ensembl chr 8:85,059,051...85,097,468
JBrowse link
G Gclm glutamate cysteine ligase, modifier subunit multiple interactions ISO cyanidin 3-O-glucoside promotes the reaction [[IL1A protein co-treated with TNF protein co-treated with IFNG protein] results in increased expression of GCLM mRNA] CTD PMID:27818126 NCBI chr 2:225,827,504...225,847,876
Ensembl chr 2:225,827,504...225,847,874
JBrowse link
G Gnrh1 gonadotropin releasing hormone 1 multiple interactions ISO cyanidin 3-O-glucoside inhibits the reaction [Cadmium Chloride results in increased expression of GNRH1 mRNA] CTD PMID:31014900 NCBI chr15:44,441,856...44,446,064
Ensembl chr15:44,442,555...44,442,875
Ensembl chr15:44,442,555...44,442,875
JBrowse link
G Hif1a hypoxia inducible factor 1 subunit alpha multiple interactions
decreases expression
ISO cyanidin 3-O-glucoside inhibits the reaction [Oxygen deficiency results in increased expression of HIF1A protein]
cyanidin 3-O-glucoside results in decreased expression of HIF1A protein
CTD PMID:24518827 NCBI chr 6:96,810,868...96,856,303
Ensembl chr 6:96,810,907...96,856,052
JBrowse link
G Hmox1 heme oxygenase 1 increases expression
multiple interactions
ISO cyanidin 3-O-glucoside results in increased expression of HMOX1 mRNA
[IL1A protein co-treated with TNF protein co-treated with IFNG protein co-treated with cyanidin 3-O-glucoside] results in increased expression of HMOX1 mRNA; cyanidin 3-O-glucoside inhibits the reaction [AGT protein results in decreased expression of HMOX1 protein]
CTD PMID:24518827, PMID:26422990, PMID:27793764, PMID:27818126, PMID:27983965 NCBI chr19:14,508,634...14,515,455
Ensembl chr19:14,508,616...14,515,456
JBrowse link
G Ifng interferon gamma multiple interactions ISO [IL1A protein co-treated with TNF protein co-treated with IFNG protein co-treated with cyanidin 3-O-glucoside] results in increased activity of NFE2L2 protein; [IL1A protein co-treated with TNF protein co-treated with IFNG protein co-treated with cyanidin 3-O-glucoside] results in increased expression of GCLC mRNA; [IL1A protein co-treated with TNF protein co-treated with IFNG protein co-treated with cyanidin 3-O-glucoside] results in increased expression of HMOX1 mRNA; [IL1A protein co-treated with TNF protein co-treated with IFNG protein co-treated with cyanidin 3-O-glucoside] results in increased expression of PPARG protein; cyanidin 3-O-glucoside promotes the reaction [[IL1A protein co-treated with TNF protein co-treated with IFNG protein] results in increased expression of GCLM mRNA]; Mesalamine inhibits the reaction [[IL1A protein co-treated with TNF protein co-treated with IFNG protein co-treated with cyanidin 3-O-glucoside] results in increased expression of PPARG protein] CTD PMID:27818126 NCBI chr 7:61,337,383...61,341,419
Ensembl chr 7:61,337,381...61,341,419
JBrowse link
G Il1a interleukin 1 alpha multiple interactions ISO [IL1A protein co-treated with TNF protein co-treated with IFNG protein co-treated with cyanidin 3-O-glucoside] results in increased activity of NFE2L2 protein; [IL1A protein co-treated with TNF protein co-treated with IFNG protein co-treated with cyanidin 3-O-glucoside] results in increased expression of GCLC mRNA; [IL1A protein co-treated with TNF protein co-treated with IFNG protein co-treated with cyanidin 3-O-glucoside] results in increased expression of HMOX1 mRNA; [IL1A protein co-treated with TNF protein co-treated with IFNG protein co-treated with cyanidin 3-O-glucoside] results in increased expression of PPARG protein; cyanidin 3-O-glucoside promotes the reaction [[IL1A protein co-treated with TNF protein co-treated with IFNG protein] results in increased expression of GCLM mRNA]; Mesalamine inhibits the reaction [[IL1A protein co-treated with TNF protein co-treated with IFNG protein co-treated with cyanidin 3-O-glucoside] results in increased expression of PPARG protein] CTD PMID:27818126 NCBI chr 3:121,824,712...121,836,122
Ensembl chr 3:121,825,412...121,836,086
JBrowse link
G Il6 interleukin 6 multiple interactions ISO cyanidin 3-O-glucoside inhibits the reaction [TNF protein results in increased expression of IL6 mRNA] CTD PMID:27793764 NCBI chr 4:3,043,231...3,047,807
Ensembl chr 4:3,043,231...3,047,807
JBrowse link
G Kiss1 KiSS-1 metastasis-suppressor multiple interactions ISO cyanidin 3-O-glucoside inhibits the reaction [Cadmium Chloride results in increased expression of KISS1 mRNA] CTD PMID:31014900 NCBI chr13:50,529,506...50,537,603
Ensembl chr13:50,529,510...50,535,389
JBrowse link
G Lhb luteinizing hormone subunit beta multiple interactions ISO [cyanidin 3-O-glucoside co-treated with Cadmium Chloride] results in increased secretion of LHB protein CTD PMID:31014900 NCBI chr 1:101,409,992...101,413,725
Ensembl chr 1:101,410,019...101,413,724
JBrowse link
G Map2k4 mitogen activated protein kinase kinase 4 multiple interactions ISO cyanidin 3-O-glucoside inhibits the reaction [7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide results in increased phosphorylation of MAP2K4 protein] CTD PMID:21501596 NCBI chr10:52,196,121...52,301,887
Ensembl chr10:52,196,124...52,290,657
JBrowse link
G Mapk1 mitogen activated protein kinase 1 multiple interactions ISO cyanidin 3-O-glucoside inhibits the reaction [7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide results in increased phosphorylation of MAPK1 protein] CTD PMID:21501596 NCBI chr11:88,203,863...88,273,301
Ensembl chr11:88,211,599...88,273,254
JBrowse link
G Mapk3 mitogen activated protein kinase 3 multiple interactions ISO cyanidin 3-O-glucoside inhibits the reaction [7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide results in increased phosphorylation of MAPK3 protein] CTD PMID:21501596 NCBI chr 1:198,192,773...198,198,975
Ensembl chr 1:198,192,773...198,198,975
JBrowse link
G Mmp2 matrix metallopeptidase 2 multiple interactions ISO cyanidin 3-O-glucoside inhibits the reaction [Oxygen deficiency results in increased expression of and results in increased activity of MMP2 protein] CTD PMID:24518827 NCBI chr19:15,542,771...15,570,589
Ensembl chr19:15,542,765...15,570,611
JBrowse link
G Nfe2l2 nuclear factor, erythroid 2-like 2 increases activity
multiple interactions
EXP
ISO
cyanidin 3-O-glucoside results in increased activity of NFE2L2 protein
[IL1A protein co-treated with TNF protein co-treated with IFNG protein co-treated with cyanidin 3-O-glucoside] results in increased activity of NFE2L2 protein
CTD PMID:27166148, PMID:27818126 NCBI chr 3:62,497,568...62,525,146
Ensembl chr 3:62,497,571...62,524,996
JBrowse link
G Nfkbia NFKB inhibitor alpha multiple interactions ISO cyanidin 3-O-glucoside inhibits the reaction [AGT protein results in increased degradation of NFKBIA protein]; cyanidin 3-O-glucoside inhibits the reaction [TNF protein results in increased expression of NFKBIA protein modified form] CTD PMID:27793764, PMID:27983965 NCBI chr 6:76,267,227...76,270,457
Ensembl chr 6:76,267,228...76,270,457
JBrowse link
G Nos2 nitric oxide synthase 2 multiple interactions ISO 4-methyl-N1-(3-phenylpropyl)benzene-1,2-diamine inhibits the reaction [cyanidin 3-O-glucoside inhibits the reaction [AGT protein results in increased expression of NOS2 protein]]; cyanidin 3-O-glucoside inhibits the reaction [AGT protein results in increased expression of NOS2 protein] CTD PMID:27983965 NCBI chr10:66,188,290...66,221,621
Ensembl chr10:66,189,786...66,313,190
JBrowse link
G Nqo1 NAD(P)H quinone dehydrogenase 1 increases expression ISO cyanidin 3-O-glucoside results in increased expression of NQO1 mRNA CTD PMID:26422990, PMID:27793764 NCBI chr19:38,422,210...38,437,103
Ensembl chr19:38,422,164...38,437,180
JBrowse link
G Pik3ca phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha increases expression ISO cyanidin 3-O-glucoside results in increased expression of PIK3CA mRNA CTD PMID:30597948 NCBI chr 2:118,831,350...118,861,456
Ensembl chr 2:118,831,350...118,861,454
JBrowse link
G Pik3r1 phosphoinositide-3-kinase regulatory subunit 1 increases expression ISO cyanidin 3-O-glucoside results in increased expression of PIK3R1 mRNA CTD PMID:30597948 NCBI chr 2:31,742,326...31,826,882
Ensembl chr 2:31,745,088...31,826,867
JBrowse link
G Pparg peroxisome proliferator-activated receptor gamma multiple interactions ISO [IL1A protein co-treated with TNF protein co-treated with IFNG protein co-treated with cyanidin 3-O-glucoside] results in increased expression of PPARG protein; Mesalamine inhibits the reaction [[IL1A protein co-treated with TNF protein co-treated with IFNG protein co-treated with cyanidin 3-O-glucoside] results in increased expression of PPARG protein] CTD PMID:27818126 NCBI chr 4:147,274,055...147,399,383
Ensembl chr 4:147,274,107...147,399,380
JBrowse link
G Prkaca protein kinase cAMP-activated catalytic subunit alpha multiple interactions ISO cyanidin 3-O-glucoside inhibits the reaction [Cadmium Chloride results in decreased expression of PRKACA protein] CTD PMID:31014900 NCBI chr19:25,095,089...25,118,869
Ensembl chr19:25,095,089...25,118,860
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 multiple interactions ISO cyanidin 3-O-glucoside inhibits the reaction [7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide results in increased expression of PTGS2 mRNA]; cyanidin 3-O-glucoside inhibits the reaction [7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide results in increased expression of PTGS2 protein]
cyanidin 3-O-glucoside inhibits the reaction [TNF protein results in increased expression of PTGS2 protein]
CTD PMID:21501596, PMID:27793764 NCBI chr13:67,351,230...67,356,920
Ensembl chr13:67,351,087...67,359,335
JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit multiple interactions ISO cyanidin 3-O-glucoside affects the localization of and results in decreased activity of RELA protein; cyanidin 3-O-glucoside inhibits the reaction [AGT protein results in increased expression of and affects the localization of RELA protein]; cyanidin 3-O-glucoside inhibits the reaction [Palmitic Acid affects the localization of and results in increased activity of RELA protein] CTD PMID:26422990, PMID:27983965 NCBI chr 1:220,992,770...221,003,249
Ensembl chr 1:220,992,770...221,003,249
JBrowse link
G Sele selectin E multiple interactions ISO cyanidin 3-O-glucoside inhibits the reaction [Palmitic Acid results in increased expression of SELE mRNA]; cyanidin 3-O-glucoside inhibits the reaction [TNF protein results in increased expression of SELE protein] CTD PMID:26422990, PMID:30611791 NCBI chr13:82,355,234...82,365,323
Ensembl chr13:82,355,471...82,365,341
JBrowse link
G Star steroidogenic acute regulatory protein multiple interactions ISO cyanidin 3-O-glucoside inhibits the reaction [Cadmium Chloride results in decreased expression of STAR protein] CTD PMID:31014900 NCBI chr16:71,036,204...71,040,847
Ensembl chr16:71,036,204...71,040,847
JBrowse link
G Stat3 signal transducer and activator of transcription 3 increases expression ISO cyanidin 3-O-glucoside results in increased expression of STAT3 mRNA CTD PMID:30597948 NCBI chr10:88,790,401...88,842,263
Ensembl chr10:88,790,408...88,842,233
JBrowse link
G Tnf tumor necrosis factor multiple interactions ISO [IL1A protein co-treated with TNF protein co-treated with IFNG protein co-treated with cyanidin 3-O-glucoside] results in increased activity of NFE2L2 protein; [IL1A protein co-treated with TNF protein co-treated with IFNG protein co-treated with cyanidin 3-O-glucoside] results in increased expression of GCLC mRNA; [IL1A protein co-treated with TNF protein co-treated with IFNG protein co-treated with cyanidin 3-O-glucoside] results in increased expression of HMOX1 mRNA; [IL1A protein co-treated with TNF protein co-treated with IFNG protein co-treated with cyanidin 3-O-glucoside] results in increased expression of PPARG protein; cyanidin 3-O-glucoside inhibits the reaction [TNF protein results in decreased abundance of Antioxidants]; cyanidin 3-O-glucoside inhibits the reaction [TNF protein results in decreased abundance of Glutathione]; cyanidin 3-O-glucoside inhibits the reaction [TNF protein results in increased abundance of Dinoprostone]; cyanidin 3-O-glucoside inhibits the reaction [TNF protein results in increased abundance of Thromboxane B2]; cyanidin 3-O-glucoside inhibits the reaction [TNF protein results in increased expression of IL6 mRNA]; cyanidin 3-O-glucoside inhibits the reaction [TNF protein results in increased expression of NFKBIA protein modified form]; cyanidin 3-O-glucoside inhibits the reaction [TNF protein results in increased expression of PTGS2 protein]; cyanidin 3-O-glucoside inhibits the reaction [TNF protein results in increased expression of SELE protein]; cyanidin 3-O-glucoside promotes the reaction [[IL1A protein co-treated with TNF protein co-treated with IFNG protein] results in increased expression of GCLM mRNA]; Mesalamine inhibits the reaction [[IL1A protein co-treated with TNF protein co-treated with IFNG protein co-treated with cyanidin 3-O-glucoside] results in increased expression of PPARG protein] CTD PMID:27793764, PMID:27818126, PMID:30611791 NCBI chr20:5,189,382...5,192,000
Ensembl chr20:5,189,390...5,192,000
JBrowse link
G Vcam1 vascular cell adhesion molecule 1 multiple interactions ISO cyanidin 3-O-glucoside inhibits the reaction [Palmitic Acid results in increased expression of VCAM1 mRNA] CTD PMID:26422990 NCBI chr 2:219,071,193...219,090,931
Ensembl chr 2:219,071,193...219,097,619
JBrowse link
cyanidin cation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ahr aryl hydrocarbon receptor increases activity ISO cyanidin results in increased activity of AHR protein CTD PMID:23419638 NCBI chr 6:54,963,990...55,001,806
Ensembl chr 6:54,963,990...55,001,464
JBrowse link
G Ccn1 cellular communication network factor 1 multiple interactions ISO
EXP
cyanidin inhibits the reaction [[IL17A protein co-treated with Freund's Adjuvant] results in increased expression of CCN1 protein]
cyanidin inhibits the reaction [Freund's Adjuvant results in increased expression of CCN1 protein]
CTD PMID:32044269 NCBI chr 2:251,529,354...251,532,312
Ensembl chr 2:251,529,354...251,532,312
JBrowse link
G Csf2 colony stimulating factor 2 multiple interactions EXP
ISO
cyanidin inhibits the reaction [Freund's Adjuvant results in increased expression of CSF2 protein]
cyanidin inhibits the reaction [[IL17A protein co-treated with Freund's Adjuvant] results in increased expression of CSF2 mRNA]; cyanidin inhibits the reaction [[IL17A protein co-treated with Freund's Adjuvant] results in increased expression of CSF2 protein]
CTD PMID:32044269 NCBI chr10:39,602,089...39,604,070
Ensembl chr10:39,602,089...39,604,070
JBrowse link
G Hbegf heparin-binding EGF-like growth factor multiple interactions ISO cyanidin inhibits the reaction [Sodium Chloride results in increased expression of HBEGF mRNA] CTD PMID:26800359 NCBI chr18:29,330,302...29,340,185
Ensembl chr18:29,329,764...29,340,403
JBrowse link
G Hlcs holocarboxylase synthetase decreases activity ISO cyanidin results in decreased activity of HLCS protein CTD PMID:26303405 NCBI chr11:34,357,372...34,537,798
Ensembl chr11:34,352,287...34,526,931
JBrowse link
G Hmox1 heme oxygenase 1 affects expression ISO cyanidin affects the expression of HMOX1 protein CTD PMID:26505893 NCBI chr19:14,508,634...14,515,455
Ensembl chr19:14,508,616...14,515,456
JBrowse link
G Il17a interleukin 17A multiple interactions ISO [cyanidin inhibits the reaction [[IL17A protein co-treated with Freund's Adjuvant] results in increased expression of and results in increased phosphorylation of STAT3 protein]] which results in increased expression of PIAS3 protein; cyanidin inhibits the reaction [[IL17A protein co-treated with Freund's Adjuvant] results in increased expression of and results in increased phosphorylation of STAT3 protein]; cyanidin inhibits the reaction [[IL17A protein co-treated with Freund's Adjuvant] results in increased expression of CCN1 protein]; cyanidin inhibits the reaction [[IL17A protein co-treated with Freund's Adjuvant] results in increased expression of CSF2 mRNA]; cyanidin inhibits the reaction [[IL17A protein co-treated with Freund's Adjuvant] results in increased expression of CSF2 protein]; cyanidin inhibits the reaction [[IL17A protein co-treated with Freund's Adjuvant] results in increased expression of IL17RA mRNA]; cyanidin inhibits the reaction [[IL17A protein co-treated with Freund's Adjuvant] results in increased expression of IL17RA protein]; cyanidin inhibits the reaction [[IL17A protein co-treated with Freund's Adjuvant] results in increased expression of IL23A mRNA]; cyanidin inhibits the reaction [[IL17A protein co-treated with Freund's Adjuvant] results in increased expression of IL23A protein]; cyanidin inhibits the reaction [[IL17A protein co-treated with Freund's Adjuvant] results in increased expression of PCNA protein]; cyanidin inhibits the reaction [[IL17A protein co-treated with Freund's Adjuvant] results in increased expression of TLR3 protein]; cyanidin inhibits the reaction [[IL17A protein co-treated with Freund's Adjuvant] results in increased phosphorylation of JAK1 protein]; cyanidin inhibits the reaction [[IL17A protein co-treated with Freund's Adjuvant] results in increased phosphorylation of JAK3 protein]; cyanidin inhibits the reaction [IL17A protein promotes the reaction [Freund's Adjuvant results in increased expression of TLR3 protein]] CTD PMID:32044269 NCBI chr 9:26,841,299...26,844,786
Ensembl chr 9:26,841,299...26,844,786
JBrowse link
G Il17ra interleukin 17 receptor A multiple interactions ISO cyanidin inhibits the reaction [[IL17A protein co-treated with Freund's Adjuvant] results in increased expression of IL17RA mRNA]; cyanidin inhibits the reaction [[IL17A protein co-treated with Freund's Adjuvant] results in increased expression of IL17RA protein] CTD PMID:32044269 NCBI chr 4:152,995,865...153,018,394
Ensembl chr 4:152,995,865...153,018,394
JBrowse link
G Il23a interleukin 23 subunit alpha multiple interactions ISO
EXP
cyanidin inhibits the reaction [[IL17A protein co-treated with Freund's Adjuvant] results in increased expression of IL23A mRNA]; cyanidin inhibits the reaction [[IL17A protein co-treated with Freund's Adjuvant] results in increased expression of IL23A protein]
cyanidin inhibits the reaction [Freund's Adjuvant results in increased expression of IL23A protein]
CTD PMID:32044269 NCBI chr 7:2,710,609...2,712,723
Ensembl chr 7:2,710,609...2,712,723
JBrowse link
G Jak1 Janus kinase 1 multiple interactions ISO cyanidin inhibits the reaction [[IL17A protein co-treated with Freund's Adjuvant] results in increased phosphorylation of JAK1 protein] CTD PMID:32044269 NCBI chr 5:119,982,503...120,091,452
Ensembl chr 5:119,982,943...120,083,904
JBrowse link
G Jak3 Janus kinase 3 multiple interactions ISO cyanidin inhibits the reaction [[IL17A protein co-treated with Freund's Adjuvant] results in increased phosphorylation of JAK3 protein] CTD PMID:32044269 NCBI chr16:20,107,471...20,120,678
Ensembl chr16:20,109,200...20,120,668
JBrowse link
G Nfe2l2 nuclear factor, erythroid 2-like 2 increases activity
affects expression
EXP
ISO
cyanidin results in increased activity of NFE2L2 protein
cyanidin affects the expression of NFE2L2 protein
CTD PMID:26505893, PMID:27166148 NCBI chr 3:62,497,568...62,525,146
Ensembl chr 3:62,497,571...62,524,996
JBrowse link
G Nos3 nitric oxide synthase 3 increases expression ISO cyanidin results in increased expression of NOS3 mRNA CTD PMID:15740983 NCBI chr 4:7,321,908...7,342,404
Ensembl chr 4:7,320,668...7,342,410
JBrowse link
G Pcna proliferating cell nuclear antigen multiple interactions ISO cyanidin inhibits the reaction [[IL17A protein co-treated with Freund's Adjuvant] results in increased expression of PCNA protein] CTD PMID:32044269 NCBI chr 3:124,880,698...124,884,570
Ensembl chr 3:124,880,698...124,884,570
JBrowse link
G Pdgfa platelet derived growth factor subunit A multiple interactions ISO cyanidin inhibits the reaction [[PDGFA protein co-treated with PDGFB protein] results in increased abundance of Reactive Oxygen Species]; cyanidin inhibits the reaction [[PDGFA protein co-treated with PDGFB protein] results in increased secretion of VEGFA protein] CTD PMID:16921400 NCBI chr12:17,734,141...17,756,186
Ensembl chr12:17,734,133...17,755,285
JBrowse link
G Pdgfb platelet derived growth factor subunit B multiple interactions ISO cyanidin inhibits the reaction [[PDGFA protein co-treated with PDGFB protein] results in increased abundance of Reactive Oxygen Species]; cyanidin inhibits the reaction [[PDGFA protein co-treated with PDGFB protein] results in increased secretion of VEGFA protein] CTD PMID:16921400 NCBI chr 7:121,215,458...121,233,092
Ensembl chr 7:121,214,628...121,232,741
JBrowse link
G Pias3 protein inhibitor of activated STAT, 3 multiple interactions ISO [cyanidin inhibits the reaction [[IL17A protein co-treated with Freund's Adjuvant] results in increased expression of and results in increased phosphorylation of STAT3 protein]] which results in increased expression of PIAS3 protein CTD PMID:32044269 NCBI chr 2:198,821,377...198,831,533
Ensembl chr 2:198,823,366...198,836,372
JBrowse link
G Stat3 signal transducer and activator of transcription 3 multiple interactions ISO
EXP
[cyanidin inhibits the reaction [[IL17A protein co-treated with Freund's Adjuvant] results in increased expression of and results in increased phosphorylation of STAT3 protein]] which results in increased expression of PIAS3 protein; cyanidin inhibits the reaction [[IL17A protein co-treated with Freund's Adjuvant] results in increased expression of and results in increased phosphorylation of STAT3 protein]
cyanidin inhibits the reaction [Freund's Adjuvant results in increased phosphorylation of STAT3 protein]
CTD PMID:32044269 NCBI chr10:88,790,401...88,842,263
Ensembl chr10:88,790,408...88,842,233
JBrowse link
G Tlr3 toll-like receptor 3 multiple interactions ISO
EXP
cyanidin inhibits the reaction [[IL17A protein co-treated with Freund's Adjuvant] results in increased expression of TLR3 protein]; cyanidin inhibits the reaction [IL17A protein promotes the reaction [Freund's Adjuvant results in increased expression of TLR3 protein]]
cyanidin inhibits the reaction [Freund's Adjuvant results in increased expression of TLR3 protein]
CTD PMID:32044269 NCBI chr16:50,016,466...50,031,011
Ensembl chr16:50,016,857...50,031,214
JBrowse link
G Tnf tumor necrosis factor multiple interactions ISO cyanidin inhibits the reaction [Benzo(a)pyrene results in increased expression of TNF mRNA] CTD PMID:28533128 NCBI chr20:5,189,382...5,192,000
Ensembl chr20:5,189,390...5,192,000
JBrowse link
G Ucp2 uncoupling protein 2 multiple interactions ISO cyanidin inhibits the reaction [Benzo(a)pyrene results in increased expression of UCP2 mRNA] CTD PMID:28533128 NCBI chr 1:165,506,375...165,512,744
Ensembl chr 1:165,506,361...165,512,744
JBrowse link
G Vegfa vascular endothelial growth factor A multiple interactions ISO cyanidin inhibits the reaction [[PDGFA protein co-treated with PDGFB protein] results in increased secretion of VEGFA protein]; cyanidin inhibits the reaction [cobaltous chloride results in increased expression of VEGFA mRNA] CTD PMID:16921400, PMID:26800359 NCBI chr 9:17,340,341...17,355,681
Ensembl chr 9:17,340,341...17,355,681
JBrowse link
delphinidin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acta2 actin alpha 2, smooth muscle multiple interactions ISO delphinidin inhibits the reaction [Carbon Tetrachloride results in increased expression of ACTA2 protein] CTD PMID:20371262 NCBI chr 1:252,537,614...252,550,394
Ensembl chr 1:252,537,615...252,550,394
JBrowse link
G Arnt aryl hydrocarbon receptor nuclear translocator multiple interactions ISO delphinidin inhibits the reaction [Hydrogen Peroxide results in increased expression of ARNT protein] CTD PMID:18603805 NCBI chr 2:196,594,178...196,651,486
Ensembl chr 2:196,594,303...196,651,179
JBrowse link
G Bak1 BCL2-antagonist/killer 1 increases expression ISO delphinidin results in increased expression of BAK1 protein CTD PMID:29451351 NCBI chr20:5,609,620...5,618,899
Ensembl chr20:5,609,625...5,618,260
JBrowse link
G Bax BCL2 associated X, apoptosis regulator increases expression
multiple interactions
decreases expression
ISO delphinidin results in increased expression of BAX protein
2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [delphinidin promotes the reaction [TGFB1 results in decreased expression of BAX protein]]; delphinidin promotes the reaction [TGFB1 results in decreased expression of BAX protein]
delphinidin results in decreased expression of BAX protein
CTD PMID:15740068, PMID:19818742, PMID:30365941 NCBI chr 1:101,451,801...101,457,207
Ensembl chr 1:101,451,802...101,457,207
JBrowse link
G Bcl2 BCL2, apoptosis regulator decreases expression
multiple interactions
increases expression
ISO delphinidin results in decreased expression of BCL2 protein
2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [delphinidin inhibits the reaction [TGFB1 results in decreased expression of BCL2 protein]]; delphinidin inhibits the reaction [TGFB1 results in decreased expression of BCL2 protein]
delphinidin results in increased expression of BCL2 protein
CTD PMID:15740068, PMID:19818742, PMID:29451351, PMID:30365941 NCBI chr13:26,605,426...26,769,374
Ensembl chr13:26,605,426...26,769,374
JBrowse link
G Bid BH3 interacting domain death agonist multiple interactions ISO [delphinidin results in increased susceptibility to sodium arsenite] which results in decreased expression of BID protein CTD PMID:30125548 NCBI chr 4:153,439,812...153,465,247
Ensembl chr 4:153,442,218...153,465,203
JBrowse link
G Btg2 BTG anti-proliferation factor 2 affects expression ISO delphinidin affects the expression of BTG2 mRNA CTD PMID:19182879 NCBI chr13:50,913,185...50,916,944
Ensembl chr13:50,913,180...50,916,982
JBrowse link
G Casp3 caspase 3 increases activity
increases cleavage
multiple interactions
ISO delphinidin results in increased activity of CASP3 protein
delphinidin results in increased cleavage of CASP3 protein
2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [delphinidin inhibits the reaction [TGFB1 results in increased expression of CASP3 protein]]; [delphinidin results in increased susceptibility to sodium arsenite] which results in increased cleavage of CASP3 protein; delphinidin inhibits the reaction [TGFB1 results in increased expression of CASP3 protein]
CTD PMID:15740068, PMID:29451351, PMID:30125548, PMID:30365941 NCBI chr16:48,845,011...48,863,249
Ensembl chr16:48,845,012...48,863,204
JBrowse link
G Casp8 caspase 8 multiple interactions ISO [delphinidin results in increased susceptibility to sodium arsenite] which results in increased cleavage of CASP8 protein CTD PMID:30125548 NCBI chr 9:65,614,142...65,662,624
Ensembl chr 9:65,614,142...65,662,106
JBrowse link
G Casp9 caspase 9 multiple interactions ISO [delphinidin results in increased susceptibility to sodium arsenite] which results in increased cleavage of CASP9 protein CTD PMID:30125548 NCBI chr 5:160,356,211...160,373,774
Ensembl chr 5:160,355,833...160,373,778
JBrowse link
G Cdh1 cadherin 1 increases expression ISO delphinidin results in increased expression of CDH1 protein CTD PMID:29451351 NCBI chr19:38,768,467...38,838,395
Ensembl chr19:38,768,467...38,838,395
JBrowse link
G Cdh2 cadherin 2 decreases expression ISO delphinidin results in decreased expression of CDH2 protein CTD PMID:29451351 NCBI chr18:8,146,971...8,366,037
Ensembl chr18:8,146,971...8,360,684
JBrowse link
G Cidea cell death-inducing DFFA-like effector a increases expression ISO delphinidin results in increased expression of CIDEA mRNA CTD PMID:19182879 NCBI chr18:63,082,861...63,108,450
Ensembl chr18:63,098,144...63,108,051
JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 decreases activity ISO delphinidin results in decreased activity of CYP1A1 protein CTD PMID:23419638 NCBI chr 8:62,472,087...62,478,122
Ensembl chr 8:62,472,095...62,478,147
JBrowse link
G Egfr epidermal growth factor receptor decreases phosphorylation ISO delphinidin results in decreased phosphorylation of EGFR protein CTD PMID:18618485 NCBI chr14:99,919,485...100,104,136
Ensembl chr14:99,919,485...100,098,796
JBrowse link
G Epas1 endothelial PAS domain protein 1 multiple interactions ISO delphinidin inhibits the reaction [Hydrogen Peroxide results in increased expression of EPAS1 protein] CTD PMID:18603805 NCBI chr 6:10,306,508...10,385,239
Ensembl chr 6:10,306,405...10,387,265
JBrowse link
G Erbb2 erb-b2 receptor tyrosine kinase 2 decreases phosphorylation ISO delphinidin results in decreased phosphorylation of ERBB2 protein CTD PMID:18618485 NCBI chr10:86,367,596...86,391,728
Ensembl chr10:86,367,596...86,391,728
JBrowse link
G Hif1a hypoxia inducible factor 1 subunit alpha multiple interactions ISO delphinidin inhibits the reaction [Hydrogen Peroxide results in increased expression of HIF1A protein] CTD PMID:18603805 NCBI chr 6:96,810,868...96,856,303
Ensembl chr 6:96,810,907...96,856,052
JBrowse link
G Hif3a hypoxia inducible factor 3 subunit alpha multiple interactions ISO delphinidin inhibits the reaction [Hydrogen Peroxide results in increased expression of HIF3A protein] CTD PMID:18603805 NCBI chr 1:78,976,318...78,997,869
Ensembl chr 1:78,976,318...78,997,869
JBrowse link
G Hmox1 heme oxygenase 1 increases expression EXP delphinidin results in increased expression of HMOX1 protein CTD PMID:30266311 NCBI chr19:14,508,634...14,515,455
Ensembl chr19:14,508,616...14,515,456
JBrowse link
G Jun Jun proto-oncogene, AP-1 transcription factor subunit increases expression ISO delphinidin results in increased expression of JUN mRNA CTD PMID:15740068 NCBI chr 5:114,011,184...114,014,277
Ensembl chr 5:114,011,189...114,014,277
JBrowse link
G Mapk1 mitogen activated protein kinase 1 decreases phosphorylation ISO delphinidin results in decreased phosphorylation of MAPK1 protein CTD PMID:18618485, PMID:29451351 NCBI chr11:88,203,863...88,273,301
Ensembl chr11:88,211,599...88,273,254
JBrowse link
G Mapk3 mitogen activated protein kinase 3 decreases phosphorylation ISO delphinidin results in decreased phosphorylation of MAPK3 protein CTD PMID:18618485, PMID:29451351 NCBI chr 1:198,192,773...198,198,975
Ensembl chr 1:198,192,773...198,198,975
JBrowse link
G Mapk8 mitogen-activated protein kinase 8 multiple interactions ISO delphinidin results in increased phosphorylation of and results in increased activity of MAPK8 protein CTD PMID:15740068 NCBI chr16:9,620,854...9,709,342
Ensembl chr16:9,625,177...9,709,347
JBrowse link
G Mmp9 matrix metallopeptidase 9 multiple interactions ISO delphinidin promotes the reaction [Carbon Tetrachloride results in increased expression of MMP9 protein] CTD PMID:20371262 NCBI chr 3:161,413,410...161,421,473
Ensembl chr 3:161,413,298...161,421,520
JBrowse link
G Nbn nibrin increases expression ISO delphinidin results in increased expression of NBN mRNA CTD PMID:19182879 NCBI chr 5:29,622,347...29,656,877
Ensembl chr 5:29,622,281...29,656,864
JBrowse link
G Parp1 poly (ADP-ribose) polymerase 1 decreases activity
increases cleavage
ISO delphinidin results in decreased activity of PARP1 protein
delphinidin results in increased cleavage of PARP1 protein
CTD PMID:17884996, PMID:29451351 NCBI chr13:98,857,255...98,889,444
Ensembl chr13:98,857,177...98,889,716
JBrowse link
G Pcbp4 poly(rC) binding protein 4 affects expression ISO delphinidin affects the expression of PCBP4 mRNA CTD PMID:19182879 NCBI chr 8:115,154,848...115,165,706
Ensembl chr 8:115,155,470...115,165,706
JBrowse link
G Pdgfa platelet derived growth factor subunit A multiple interactions ISO delphinidin inhibits the reaction [[PDGFA protein co-treated with PDGFB protein] results in increased abundance of Reactive Oxygen Species]; delphinidin inhibits the reaction [[PDGFA protein co-treated with PDGFB protein] results in increased secretion of VEGFA protein] CTD PMID:16921400 NCBI chr12:17,734,141...17,756,186
Ensembl chr12:17,734,133...17,755,285
JBrowse link
G Pdgfb platelet derived growth factor subunit B multiple interactions ISO delphinidin inhibits the reaction [[PDGFA protein co-treated with PDGFB protein] results in increased abundance of Reactive Oxygen Species]; delphinidin inhibits the reaction [[PDGFA protein co-treated with PDGFB protein] results in increased secretion of VEGFA protein] CTD PMID:16921400 NCBI chr 7:121,215,458...121,233,092
Ensembl chr 7:121,214,628...121,232,741
JBrowse link
G Pgk1 phosphoglycerate kinase 1 multiple interactions ISO delphinidin inhibits the reaction [Hydrogen Peroxide results in increased expression of PGK1 protein] CTD PMID:18603805 NCBI chr  X:77,263,399...77,279,373
Ensembl chr  X:77,263,359...77,279,367
JBrowse link
G Snai1 snail family transcriptional repressor 1 decreases expression ISO delphinidin results in decreased expression of SNAI1 protein CTD PMID:29451351 NCBI chr 3:164,274,710...164,279,199
Ensembl chr 3:164,274,710...164,279,378
JBrowse link
G Snai2 snail family transcriptional repressor 2 decreases expression ISO delphinidin results in decreased expression of SNAI2 protein CTD PMID:29451351 NCBI chr11:90,404,421...90,406,730
Ensembl chr11:90,403,333...90,406,797
JBrowse link
G Tgfb1 transforming growth factor, beta 1 multiple interactions ISO delphinidin inhibits the reaction [Carbon Tetrachloride results in increased expression of TGFB1 protein]
2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [delphinidin inhibits the reaction [TGFB1 results in decreased expression of BCL2 protein]]; 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [delphinidin inhibits the reaction [TGFB1 results in increased expression of CASP3 protein]]; 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [delphinidin promotes the reaction [TGFB1 results in decreased expression of BAX protein]]; delphinidin inhibits the reaction [TGFB1 results in decreased expression of BCL2 protein]; delphinidin inhibits the reaction [TGFB1 results in increased abundance of Malondialdehyde]; delphinidin inhibits the reaction [TGFB1 results in increased abundance of Reactive Oxygen Species]; delphinidin inhibits the reaction [TGFB1 results in increased expression of CASP3 protein]; delphinidin promotes the reaction [TGFB1 results in decreased expression of BAX protein]
CTD PMID:20371262, PMID:30365941 NCBI chr 1:82,480,875...82,497,196
Ensembl chr 1:82,480,195...82,497,199
JBrowse link
G Tnf tumor necrosis factor multiple interactions ISO delphinidin inhibits the reaction [Carbon Tetrachloride results in increased expression of TNF protein] CTD PMID:20371262 NCBI chr20:5,189,382...5,192,000
Ensembl chr20:5,189,390...5,192,000
JBrowse link
G Top1 DNA topoisomerase I decreases activity ISO delphinidin results in decreased activity of TOP1 protein CTD PMID:19182879 NCBI chr 3:156,635,688...156,717,686
Ensembl chr 3:156,642,464...156,717,686
JBrowse link
G Top2a DNA topoisomerase II alpha decreases activity
multiple interactions
ISO delphinidin results in decreased activity of TOP2A protein
delphinidin results in decreased susceptibility to [Doxorubicin affects the activity of TOP2A protein]; delphinidin results in decreased susceptibility to [Etoposide affects the activity of TOP2A protein]
CTD PMID:19182879 NCBI chr10:86,901,467...86,930,947
Ensembl chr10:86,901,007...86,932,154
JBrowse link
G Vegfa vascular endothelial growth factor A multiple interactions ISO delphinidin inhibits the reaction [[PDGFA protein co-treated with PDGFB protein] results in increased secretion of VEGFA protein] CTD PMID:16921400 NCBI chr 9:17,340,341...17,355,681
Ensembl chr 9:17,340,341...17,355,681
JBrowse link
malvidin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Akt1 AKT serine/threonine kinase 1 multiple interactions ISO malvidin promotes the reaction [[endotoxin, Escherichia coli results in increased phosphorylation of and results in increased activity of AKT1 protein] which results in increased phosphorylation of GSK3B protein]; malvidin promotes the reaction [endotoxin, Escherichia coli results in increased phosphorylation of and results in increased activity of AKT1 protein] CTD PMID:23755222 NCBI chr 6:137,218,398...137,239,970
Ensembl chr 6:137,218,376...137,236,258
JBrowse link
G Bax BCL2 associated X, apoptosis regulator increases expression ISO malvidin results in increased expression of BAX protein CTD PMID:15964118 NCBI chr 1:101,451,801...101,457,207
Ensembl chr 1:101,451,802...101,457,207
JBrowse link
G Bcl2 BCL2, apoptosis regulator decreases expression ISO malvidin results in decreased expression of BCL2 protein CTD PMID:15964118 NCBI chr13:26,605,426...26,769,374
Ensembl chr13:26,605,426...26,769,374
JBrowse link
G Casp3 caspase 3 increases activity
multiple interactions
ISO malvidin results in increased activity of CASP3 protein
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one promotes the reaction [malvidin results in increased activity of CASP3 protein]; SB 203580 inhibits the reaction [malvidin results in increased activity of CASP3 protein]
CTD PMID:15964118 NCBI chr16:48,845,011...48,863,249
Ensembl chr16:48,845,012...48,863,204
JBrowse link
G Dusp1 dual specificity phosphatase 1 multiple interactions ISO malvidin promotes the reaction [endotoxin, Escherichia coli results in increased expression of DUSP1 mRNA]; malvidin promotes the reaction [endotoxin, Escherichia coli results in increased expression of DUSP1 protein] CTD PMID:23755222 NCBI chr10:16,970,642...16,973,425
Ensembl chr10:16,970,626...16,973,418
JBrowse link
G Gsk3b glycogen synthase kinase 3 beta multiple interactions ISO malvidin promotes the reaction [[endotoxin, Escherichia coli results in increased phosphorylation of and results in increased activity of AKT1 protein] which results in increased phosphorylation of GSK3B protein] CTD PMID:23755222 NCBI chr11:65,060,884...65,208,842
Ensembl chr11:65,066,235...65,209,268
JBrowse link
G Mapk1 mitogen activated protein kinase 1 decreases phosphorylation ISO malvidin results in decreased phosphorylation of MAPK1 protein CTD PMID:15964118 NCBI chr11:88,203,863...88,273,301
Ensembl chr11:88,211,599...88,273,254
JBrowse link
G Mapk14 mitogen activated protein kinase 14 multiple interactions ISO malvidin results in increased expression of and results in increased phosphorylation of MAPK14 protein CTD PMID:15964118 NCBI chr20:5,933,290...5,995,137
Ensembl chr20:5,933,303...5,995,137
JBrowse link
G Mapk3 mitogen activated protein kinase 3 decreases phosphorylation ISO malvidin results in decreased phosphorylation of MAPK3 protein CTD PMID:15964118 NCBI chr 1:198,192,773...198,198,975
Ensembl chr 1:198,192,773...198,198,975
JBrowse link
G Parp1 poly (ADP-ribose) polymerase 1 increases cleavage ISO malvidin results in increased cleavage of PARP1 protein CTD PMID:15964118 NCBI chr13:98,857,255...98,889,444
Ensembl chr13:98,857,177...98,889,716
JBrowse link
G Pde5a phosphodiesterase 5A decreases activity ISO malvidin results in decreased activity of PDE5A protein CTD PMID:15769121 NCBI chr 2:226,899,604...227,044,916
Ensembl chr 2:226,900,619...227,041,576
JBrowse link
G Pdgfa platelet derived growth factor subunit A multiple interactions ISO malvidin inhibits the reaction [[PDGFA protein co-treated with PDGFB protein] results in increased abundance of Reactive Oxygen Species] CTD PMID:16921400 NCBI chr12:17,734,141...17,756,186
Ensembl chr12:17,734,133...17,755,285
JBrowse link
G Pdgfb platelet derived growth factor subunit B multiple interactions ISO malvidin inhibits the reaction [[PDGFA protein co-treated with PDGFB protein] results in increased abundance of Reactive Oxygen Species] CTD PMID:16921400 NCBI chr 7:121,215,458...121,233,092
Ensembl chr 7:121,214,628...121,232,741
JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit multiple interactions ISO malvidin inhibits the reaction [endotoxin, Escherichia coli affects the localization of and results in increased phosphorylation of and results in increased activity of RELA protein] CTD PMID:23755222 NCBI chr 1:220,992,770...221,003,249
Ensembl chr 1:220,992,770...221,003,249
JBrowse link
malvidin 3-O-beta-D-glucoside term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Car1 carbonic anhydrase 1 decreases activity ISO malvidin-3-glucoside results in decreased activity of CA1 protein CTD PMID:28445001 NCBI chr 2:88,185,204...88,227,486
Ensembl chr 2:88,217,188...88,227,479
JBrowse link
G Car2 carbonic anhydrase 2 decreases activity ISO malvidin-3-glucoside results in decreased activity of CA2 protein CTD PMID:28445001 NCBI chr 2:88,097,740...88,112,868
Ensembl chr 2:88,097,720...88,113,029
JBrowse link
G Nos2 nitric oxide synthase 2 multiple interactions ISO malvidin-3-glucoside inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 protein] CTD PMID:23731018 NCBI chr10:66,188,290...66,221,621
Ensembl chr10:66,189,786...66,313,190
JBrowse link
G Pde5a phosphodiesterase 5A decreases activity ISO malvidin-3-glucoside results in decreased activity of PDE5A protein CTD PMID:15769121 NCBI chr 2:226,899,604...227,044,916
Ensembl chr 2:226,900,619...227,041,576
JBrowse link
G Sele selectin E multiple interactions ISO malvidin-3-glucoside inhibits the reaction [TNF protein results in increased expression of SELE protein] CTD PMID:30611791 NCBI chr13:82,355,234...82,365,323
Ensembl chr13:82,355,471...82,365,341
JBrowse link
G Tnf tumor necrosis factor multiple interactions ISO malvidin-3-glucoside inhibits the reaction [Lipopolysaccharides results in increased expression of TNF protein]
malvidin-3-glucoside inhibits the reaction [TNF protein results in increased expression of SELE protein]
CTD PMID:23731018, PMID:30611791 NCBI chr20:5,189,382...5,192,000
Ensembl chr20:5,189,390...5,192,000
JBrowse link
malvin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Car1 carbonic anhydrase 1 decreases activity ISO malvin results in decreased activity of CA1 protein CTD PMID:28445001 NCBI chr 2:88,185,204...88,227,486
Ensembl chr 2:88,217,188...88,227,479
JBrowse link
G Car2 carbonic anhydrase 2 decreases activity ISO malvin results in decreased activity of CA2 protein CTD PMID:28445001 NCBI chr 2:88,097,740...88,112,868
Ensembl chr 2:88,097,720...88,113,029
JBrowse link
pelargonidin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ahr aryl hydrocarbon receptor increases activity
multiple interactions
ISO pelargonidin metabolite results in increased activity of AHR protein
[pelargonidin metabolite results in increased activity of AHR protein] which results in increased expression of CYP1A1 mRNA; pelargonidin binds to and results in increased activity of AHR protein
CTD PMID:23419638, PMID:23735880 NCBI chr 6:54,963,990...55,001,806
Ensembl chr 6:54,963,990...55,001,464
JBrowse link
G Cdh1 cadherin 1 multiple interactions ISO pelargonidin inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of CDH1 mRNA]; pelargonidin inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of CDH1 protein] CTD PMID:30753810 NCBI chr19:38,768,467...38,838,395
Ensembl chr19:38,768,467...38,838,395
JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 decreases activity
increases expression
multiple interactions
ISO pelargonidin metabolite results in decreased activity of CYP1A1 protein; pelargonidin results in decreased activity of CYP1A1 protein
pelargonidin metabolite results in increased expression of CYP1A1 mRNA; pelargonidin results in increased expression of CYP1A1 mRNA
[pelargonidin metabolite results in increased activity of AHR protein] which results in increased expression of CYP1A1 mRNA; pelargonidin results in increased expression of and results in increased activity of CYP1A1 protein
CTD PMID:23419638, PMID:23735880 NCBI chr 8:62,472,087...62,478,122
Ensembl chr 8:62,472,095...62,478,147
JBrowse link
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 increases expression ISO pelargonidin results in increased expression of CYP1A2 mRNA CTD PMID:23419638 NCBI chr 8:62,451,360...62,458,244
Ensembl chr 8:62,451,329...62,458,301
JBrowse link
G Dnmt1 DNA methyltransferase 1 decreases expression ISO pelargonidin results in decreased expression of DNMT1 protein CTD PMID:31181187 NCBI chr 8:21,922,515...21,968,495
Ensembl chr 8:21,922,515...21,968,495
JBrowse link
G Dnmt3b DNA methyltransferase 3 beta decreases expression ISO pelargonidin results in decreased expression of DNMT3B protein CTD PMID:31181187 NCBI chr 3:149,131,541...149,170,061
Ensembl chr 3:149,131,785...149,208,786
JBrowse link
G Hdac1 histone deacetylase 1 decreases expression ISO pelargonidin results in decreased expression of HDAC1 protein CTD PMID:31181187 NCBI chr 5:147,716,664...147,743,723
Ensembl chr 5:147,716,664...147,743,723
JBrowse link
G Hdac2 histone deacetylase 2 decreases expression ISO pelargonidin results in decreased expression of HDAC2 protein CTD PMID:31181187 NCBI chr20:43,084,870...43,108,198
Ensembl chr20:43,084,870...43,108,198
JBrowse link
G Hdac3 histone deacetylase 3 decreases expression ISO pelargonidin results in decreased expression of HDAC3 protein CTD PMID:31181187 NCBI chr18:31,073,057...31,094,347
Ensembl chr18:31,073,058...31,094,303
JBrowse link
G Hdac4 histone deacetylase 4 decreases expression ISO pelargonidin results in decreased expression of HDAC4 protein CTD PMID:31181187 NCBI chr 9:99,052,945...99,299,715
Ensembl chr 9:99,057,089...99,299,715
JBrowse link
G Hdac7 histone deacetylase 7 decreases expression ISO pelargonidin results in decreased expression of HDAC7 protein CTD PMID:31181187 NCBI chr 7:139,280,396...139,319,108
Ensembl chr 7:139,281,187...139,318,455
JBrowse link
G Hmox1 heme oxygenase 1 increases expression ISO pelargonidin results in increased expression of HMOX1 mRNA; pelargonidin results in increased expression of HMOX1 protein CTD PMID:31181187 NCBI chr19:14,508,634...14,515,455
Ensembl chr19:14,508,616...14,515,456
JBrowse link
G Icam1 intercellular adhesion molecule 1 multiple interactions ISO pelargonidin inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of ICAM1 mRNA]; pelargonidin inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of ICAM1 protein] CTD PMID:30753810 NCBI chr 8:22,035,287...22,047,049
Ensembl chr 8:22,035,256...22,047,059
JBrowse link
G Il6 interleukin 6 multiple interactions ISO pelargonidin inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased secretion of IL6 protein] CTD PMID:30753810 NCBI chr 4:3,043,231...3,047,807
Ensembl chr 4:3,043,231...3,047,807
JBrowse link
G Mapk1 mitogen activated protein kinase 1 multiple interactions ISO pelargonidin inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased phosphorylation of MAPK1 protein] CTD PMID:30753810 NCBI chr11:88,203,863...88,273,301
Ensembl chr11:88,211,599...88,273,254
JBrowse link
G Mapk3 mitogen activated protein kinase 3 multiple interactions ISO pelargonidin inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased phosphorylation of MAPK3 protein] CTD PMID:30753810 NCBI chr 1:198,192,773...198,198,975
Ensembl chr 1:198,192,773...198,198,975
JBrowse link
G Nfe2l2 nuclear factor, erythroid 2-like 2 decreases methylation
affects response to substance
ISO pelargonidin results in decreased methylation of NFE2L2 promoter
NFE2L2 protein affects the susceptibility to pelargonidin
CTD PMID:31181187 NCBI chr 3:62,497,568...62,525,146
Ensembl chr 3:62,497,571...62,524,996
JBrowse link
G Nos2 nitric oxide synthase 2 multiple interactions ISO pelargonidin inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 mRNA]; pelargonidin inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 protein] CTD PMID:18274639 NCBI chr10:66,188,290...66,221,621
Ensembl chr10:66,189,786...66,313,190
JBrowse link
G Nqo1 NAD(P)H quinone dehydrogenase 1 increases expression ISO pelargonidin results in increased expression of NQO1 mRNA; pelargonidin results in increased expression of NQO1 protein CTD PMID:31181187 NCBI chr19:38,422,210...38,437,103
Ensembl chr19:38,422,164...38,437,180
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 multiple interactions ISO pelargonidin inhibits the reaction [Lipopolysaccharides results in increased expression of PTGS2 mRNA] CTD PMID:21341175 NCBI chr13:67,351,230...67,356,920
Ensembl chr13:67,351,087...67,359,335
JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit multiple interactions ISO pelargonidin inhibits the reaction [Lipopolysaccharides affects the localization of and results in increased activity of RELA protein]
pelargonidin inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased phosphorylation of RELA protein]
CTD PMID:18274639, PMID:30753810 NCBI chr 1:220,992,770...221,003,249
Ensembl chr 1:220,992,770...221,003,249
JBrowse link
G Tlr4 toll-like receptor 4 multiple interactions ISO pelargonidin inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of TLR4 protein] CTD PMID:30753810 NCBI chr 5:82,587,424...82,601,056
Ensembl chr 5:82,587,420...82,601,052
JBrowse link
G Tnf tumor necrosis factor multiple interactions ISO pelargonidin inhibits the reaction [Lipopolysaccharides results in increased expression of TNF]
pelargonidin inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased secretion of TNF protein]
CTD PMID:18720166, PMID:30753810 NCBI chr20:5,189,382...5,192,000
Ensembl chr20:5,189,390...5,192,000
JBrowse link
G Txnrd1 thioredoxin reductase 1 decreases activity EXP pelargonidin results in decreased activity of TXNRD1 protein modified form CTD PMID:16618767 NCBI chr 7:26,946,124...26,984,400
Ensembl chr 7:26,946,125...26,984,400
JBrowse link
G Vcam1 vascular cell adhesion molecule 1 multiple interactions ISO pelargonidin inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of VCAM1 mRNA]; pelargonidin inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of VCAM1 protein] CTD PMID:30753810 NCBI chr 2:219,071,193...219,090,931
Ensembl chr 2:219,071,193...219,097,619
JBrowse link
pelargonidin 3-O-beta-D-glucoside term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Car1 carbonic anhydrase 1 decreases activity ISO pelargonidin-3-glucoside results in decreased activity of CA1 protein CTD PMID:28445001 NCBI chr 2:88,185,204...88,227,486
Ensembl chr 2:88,217,188...88,227,479
JBrowse link
G Car2 carbonic anhydrase 2 decreases activity ISO pelargonidin-3-glucoside results in decreased activity of CA2 protein CTD PMID:28445001 NCBI chr 2:88,097,740...88,112,868
Ensembl chr 2:88,097,720...88,113,029
JBrowse link
pelargonidin 3-O-beta-D-glucoside chloride term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Car1 carbonic anhydrase 1 decreases activity ISO pelargonidin-3-glucoside results in decreased activity of CA1 protein CTD PMID:28445001 NCBI chr 2:88,185,204...88,227,486
Ensembl chr 2:88,217,188...88,227,479
JBrowse link
G Car2 carbonic anhydrase 2 decreases activity ISO pelargonidin-3-glucoside results in decreased activity of CA2 protein CTD PMID:28445001 NCBI chr 2:88,097,740...88,112,868
Ensembl chr 2:88,097,720...88,113,029
JBrowse link
peonidin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pdgfa platelet derived growth factor subunit A multiple interactions ISO peonidin inhibits the reaction [[PDGFA protein co-treated with PDGFB protein] results in increased abundance of Reactive Oxygen Species] CTD PMID:16921400 NCBI chr12:17,734,141...17,756,186
Ensembl chr12:17,734,133...17,755,285
JBrowse link
G Pdgfb platelet derived growth factor subunit B multiple interactions ISO peonidin inhibits the reaction [[PDGFA protein co-treated with PDGFB protein] results in increased abundance of Reactive Oxygen Species] CTD PMID:16921400 NCBI chr 7:121,215,458...121,233,092
Ensembl chr 7:121,214,628...121,232,741
JBrowse link
peonidin chloride term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pdgfa platelet derived growth factor subunit A multiple interactions ISO peonidin inhibits the reaction [[PDGFA protein co-treated with PDGFB protein] results in increased abundance of Reactive Oxygen Species] CTD PMID:16921400 NCBI chr12:17,734,141...17,756,186
Ensembl chr12:17,734,133...17,755,285
JBrowse link
G Pdgfb platelet derived growth factor subunit B multiple interactions ISO peonidin inhibits the reaction [[PDGFA protein co-treated with PDGFB protein] results in increased abundance of Reactive Oxygen Species] CTD PMID:16921400 NCBI chr 7:121,215,458...121,233,092
Ensembl chr 7:121,214,628...121,232,741
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19816
    chemical entity 19816
      molecular entity 19814
        ion 15935
          organic ion 8327
            organic cation 7147
              anthocyanidin cation 153
                3-hydroxy-2-phenylchromenylium 0
                3-hydroxyanthocyanidin cation 0
                5-hydroxyanthocyanidin + 103
                anthocyanidin + 2
                anthocyanidin glycoside + 2
                anthocyanin cation + 105
                capensinidin 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19816
    subatomic particle 19814
      composite particle 19814
        hadron 19814
          baryon 19814
            nucleon 19814
              atomic nucleus 19814
                atom 19814
                  main group element atom 19702
                    p-block element atom 19702
                      carbon group element atom 19608
                        carbon atom 19597
                          organic molecular entity 19597
                            organic molecule 19522
                              organic cyclic compound 19320
                                organic heterocyclic compound 18432
                                  oxacycle 17200
                                    benzopyran 10142
                                      1-benzopyran 9858
                                        chromenes 932
                                          chromene 153
                                            2H-chromene 153
                                              chromenyliums 153
                                                chromenylium 153
                                                  flavylium 153
                                                    anthocyanidin cation 153
                                                      3-hydroxy-2-phenylchromenylium 0
                                                      3-hydroxyanthocyanidin cation 0
                                                      5-hydroxyanthocyanidin + 103
                                                      anthocyanidin + 2
                                                      anthocyanidin glycoside + 2
                                                      anthocyanin cation + 105
                                                      capensinidin 0
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.