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ONTOLOGY REPORT - ANNOTATIONS


Term:cholic acid
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Accession:CHEBI:16359 term browser browse the term
Definition:A bile acid that is 5beta-cholan-24-oic acid bearing three alpha-hydroxy substituents at position 3, 7 and 12.
Synonyms:exact_synonym: 3alpha,7alpha,12alpha-trihydroxy-5beta-cholan-24-oic acid
 related_synonym: (3alpha,5beta,7alpha,12alpha)-3,7,12-trihydroxycholan-24-oic acid;   3alpha,7alpha,12alpha-Trihydroxy-5beta-cholanate;   3alpha,7alpha,12alpha-Trihydroxy-5beta-cholanic acid;   Cholsaeure;   Formula=C24H40O5;   InChI=1S/C24H40O5/c1-13(4-7-21(28)29)16-5-6-17-22-18(12-20(27)24(16,17)3)23(2)9-8-15(25)10-14(23)11-19(22)26/h13-20,22,25-27H,4-12H2,1-3H3,(H,28,29)/t13-,14+,15-,16-,17+,18+,19-,20+,22+,23+,24-/m1/s1;   InChIKey=BHQCQFFYRZLCQQ-OELDTZBJSA-N;   SMILES=[H][C@@]12C[C@H](O)CC[C@]1(C)[C@@]1([H])C[C@H](O)[C@]3(C)[C@]([H])(CC[C@@]3([H])[C@]1([H])[C@H](O)C2)[C@H](C)CCC(O)=O
 alt_id: CHEBI:1694;   CHEBI:20223;   CHEBI:23210;   CHEBI:41494
 xref: Beilstein:2822009 "ChemIDplus";   CAS:81-25-4 "ChemIDplus";   CAS:81-25-4 "KEGG COMPOUND";   CAS:81-25-4 "NIST Chemistry WebBook";   DrugBank:DB02659;   Drug_Central:3096 "DrugCentral";   HMDB:HMDB0000619;   KEGG:C00695;   LINCS:LSM-5541;   LIPID_MAPS_instance:LMST04010001 "LIPID MAPS"
 xref_mesh: MESH:D019826
 xref: MetaCyc:CHOLATE;   PDBeChem:CHD;   PMID:22770225 "Europe PMC";   Reaxys:2822009 "Reaxys";   Wikipedia:Cholic_Acid
 cyclic_relationship: is_conjugate_acid_of CHEBI:29747


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cholic acid term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G ABCA1 ATP binding cassette subfamily A member 1 JBrowse link 9 104,781,006 104,928,232 RGD:6480464
G ABCA8 ATP binding cassette subfamily A member 8 JBrowse link 17 68,867,285 68,955,415 RGD:6480464
G ABCA9 ATP binding cassette subfamily A member 9 JBrowse link 17 68,974,488 69,078,978 RGD:6480464
G ABCB1 ATP binding cassette subfamily B member 1 JBrowse link 7 87,503,017 87,713,323 RGD:6480464
G ABCB11 ATP binding cassette subfamily B member 11 JBrowse link 2 168,915,468 169,031,396 RGD:6480464
G ABCB4 ATP binding cassette subfamily B member 4 JBrowse link 7 87,398,988 87,476,722 RGD:6480464
G ABCC1 ATP binding cassette subfamily C member 1 JBrowse link 16 15,949,616 16,143,062 RGD:6480464
G ABCC2 ATP binding cassette subfamily C member 2 JBrowse link 10 99,782,602 99,853,741 RGD:6480464
G ABCC3 ATP binding cassette subfamily C member 3 JBrowse link 17 50,634,881 50,692,253 RGD:6480464
G ABCG1 ATP binding cassette subfamily G member 1 JBrowse link 21 42,199,689 42,304,387 RGD:6480464
G ABCG5 ATP binding cassette subfamily G member 5 JBrowse link 2 43,806,154 43,838,840 RGD:6480464
G ABCG8 ATP binding cassette subfamily G member 8 JBrowse link 2 43,831,942 43,882,988 RGD:6480464
G AHR aryl hydrocarbon receptor JBrowse link 7 17,298,652 17,346,147 RGD:6480464
G AKR1C4 aldo-keto reductase family 1 member C4 JBrowse link 10 5,196,837 5,218,949 RGD:6480464
G AKT1 AKT serine/threonine kinase 1 JBrowse link 14 104,769,349 104,795,748 RGD:6480464
G ATP8B1 ATPase phospholipid transporting 8B1 JBrowse link 18 57,646,426 57,803,822 RGD:6480464
G CASP3 caspase 3 JBrowse link 4 184,627,696 184,649,475 RGD:6480464
G CAT catalase JBrowse link 11 34,438,934 34,472,060 RGD:6480464
G CCND1 cyclin D1 JBrowse link 11 69,641,156 69,654,474 RGD:6480464
G CDKN1A cyclin dependent kinase inhibitor 1A JBrowse link 6 36,676,463 36,687,332 RGD:6480464
G CHEK1 checkpoint kinase 1 JBrowse link 11 125,624,910 125,676,256 RGD:6480464
G CYP27A1 cytochrome P450 family 27 subfamily A member 1 JBrowse link 2 218,781,733 218,815,293 RGD:6480464
G CYP2A6 cytochrome P450 family 2 subfamily A member 6 JBrowse link 19 40,843,541 40,850,447 RGD:6480464
G CYP2B6 cytochrome P450 family 2 subfamily B member 6 JBrowse link 19 40,991,282 41,018,398 RGD:6480464
G CYP3A4 cytochrome P450 family 3 subfamily A member 4 JBrowse link 7 99,756,967 99,784,184 RGD:6480464
G CYP7A1 cytochrome P450 family 7 subfamily A member 1 JBrowse link 8 58,490,178 58,500,163 RGD:6480464
G CYP7B1 cytochrome P450 family 7 subfamily B member 1 JBrowse link 8 64,586,575 64,798,737 RGD:6480464
G CYP8B1 cytochrome P450 family 8 subfamily B member 1 JBrowse link 3 42,872,192 42,875,879 RGD:6480464
G FABP6 fatty acid binding protein 6 JBrowse link 5 160,187,381 160,238,722 RGD:6480464
G FGF19 fibroblast growth factor 19 JBrowse link 11 69,698,238 69,704,022 RGD:6480464
G FMO3 flavin containing dimethylaniline monoxygenase 3 JBrowse link 1 171,090,873 171,117,819 RGD:6480464
G FMO4 flavin containing dimethylaniline monoxygenase 4 JBrowse link 1 171,314,131 171,342,084 RGD:6480464
G FOSL1 FOS like 1, AP-1 transcription factor subunit JBrowse link 11 65,892,049 65,900,526 RGD:6480464
G GPBAR1 G protein-coupled bile acid receptor 1 JBrowse link 2 218,259,496 218,263,861 RGD:6480464
G GSTA1 glutathione S-transferase alpha 1 JBrowse link 6 52,791,371 52,803,827 RGD:6480464
G GSTA4 glutathione S-transferase alpha 4 JBrowse link 6 52,977,952 52,995,332 RGD:6480464
G GSTM1 glutathione S-transferase mu 1 JBrowse link 1 109,687,817 109,693,745 RGD:6480464
G GSTM2 glutathione S-transferase mu 2 JBrowse link 1 109,668,022 109,683,997 RGD:6480464
G GSTM3 glutathione S-transferase mu 3 JBrowse link 1 109,733,932 109,741,038 RGD:6480464
G GSTT2B glutathione S-transferase theta 2B (gene/pseudogene) JBrowse link 22 23,957,414 23,961,206 RGD:6480464
G HELLS helicase, lymphoid specific JBrowse link 10 94,545,767 94,613,905 RGD:6480464
G HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase JBrowse link 5 75,336,334 75,362,116 RGD:6480464
G HNF4A hepatocyte nuclear factor 4 alpha JBrowse link 20 44,355,699 44,434,596 RGD:6480464
G HSD11B1 hydroxysteroid 11-beta dehydrogenase 1 JBrowse link 1 209,686,180 209,734,950 RGD:6480464
G IL1B interleukin 1 beta JBrowse link 2 112,829,751 112,836,843 RGD:6480464
G IL1RL1 interleukin 1 receptor like 1 JBrowse link 2 102,311,502 102,352,367 RGD:6480464
G LCAT lecithin-cholesterol acyltransferase JBrowse link 16 67,939,750 67,944,120 RGD:6480464
G LDLR low density lipoprotein receptor JBrowse link 19 11,089,432 11,133,820 RGD:6480464
G LPL lipoprotein lipase JBrowse link 8 19,939,253 19,967,259 RGD:6480464
G LRP2 LDL receptor related protein 2 JBrowse link 2 169,127,109 169,362,597 RGD:6480464
G MAP1LC3B microtubule associated protein 1 light chain 3 beta JBrowse link 16 87,392,336 87,404,774 RGD:6480464
G MAPK1 mitogen-activated protein kinase 1 JBrowse link 22 21,759,657 21,867,680 RGD:6480464
G MAPK3 mitogen-activated protein kinase 3 JBrowse link 16 30,114,105 30,123,309 RGD:6480464
G MCM3 minichromosome maintenance complex component 3 JBrowse link 6 52,264,015 52,284,742 RGD:6480464
G MGST3 microsomal glutathione S-transferase 3 JBrowse link 1 165,631,234 165,656,136 RGD:6480464
G MT1X metallothionein 1X JBrowse link 16 56,682,470 56,684,196 RGD:6480464
G NFE2L2 nuclear factor, erythroid 2 like 2 JBrowse link 2 177,230,303 177,265,131 RGD:6480464
G NFKBIA NFKB inhibitor alpha JBrowse link 14 35,401,513 35,404,749 RGD:6480464
G NQO1 NAD(P)H quinone dehydrogenase 1 JBrowse link 16 69,709,401 69,726,560 RGD:6480464
G NR0B2 nuclear receptor subfamily 0 group B member 2 JBrowse link 1 26,911,489 26,914,110 RGD:6480464
G NR1H3 nuclear receptor subfamily 1 group H member 3 JBrowse link 11 47,248,300 47,269,033 RGD:6480464
G NR1H4 nuclear receptor subfamily 1 group H member 4 JBrowse link 12 100,473,866 100,564,414 RGD:6480464
G NR1I2 nuclear receptor subfamily 1 group I member 2 JBrowse link 3 119,780,484 119,818,485 RGD:6480464
G ORM1 orosomucoid 1 JBrowse link 9 114,322,628 114,326,479 RGD:6480464
G ORM2 orosomucoid 2 JBrowse link 9 114,329,872 114,333,251 RGD:6480464
G PAPSS2 3'-phosphoadenosine 5'-phosphosulfate synthase 2 JBrowse link 10 87,659,878 87,747,705 RGD:6480464
G PCNA proliferating cell nuclear antigen JBrowse link 20 5,114,953 5,126,622 RGD:6480464
G PIK3R5 phosphoinositide-3-kinase regulatory subunit 5 JBrowse link 17 8,878,916 8,965,712 RGD:6480464
G PON1 paraoxonase 1 JBrowse link 7 95,297,676 95,324,532 RGD:6480464
G POR cytochrome p450 oxidoreductase JBrowse link 7 75,915,155 75,986,855 RGD:6480464
G PPARA peroxisome proliferator activated receptor alpha JBrowse link 22 46,150,526 46,243,756 RGD:6480464
G RAB7A RAB7A, member RAS oncogene family JBrowse link 3 128,726,183 128,814,798 RGD:6480464
G RELA RELA proto-oncogene, NF-kB subunit JBrowse link 11 65,653,596 65,662,972 RGD:6480464
G RIF1 replication timing regulatory factor 1 JBrowse link 2 151,409,902 151,534,200 RGD:6480464
G SCARB1 scavenger receptor class B member 1 JBrowse link 12 124,776,856 124,863,864 RGD:6480464
G SLC10A1 solute carrier family 10 member 1 JBrowse link 14 69,775,416 69,797,241 RGD:6480464
G SLC10A2 solute carrier family 10 member 2 JBrowse link 13 103,043,998 103,066,417 RGD:6480464
G SLC22A20P solute carrier family 22 member 20, pseudogene JBrowse link 11 65,213,840 65,242,757 RGD:6480464
G SLC27A5 solute carrier family 27 member 5 JBrowse link 19 58,498,333 58,512,065 RGD:6480464
G SLC2A1 solute carrier family 2 member 1 JBrowse link 1 42,925,375 42,958,868 RGD:6480464
G SLC51A solute carrier family 51 subunit alpha JBrowse link 3 196,216,534 196,233,427 RGD:6480464
G SLC51B solute carrier family 51 subunit beta JBrowse link 15 65,045,387 65,053,397 RGD:6480464
G SLCO1A2 solute carrier organic anion transporter family member 1A2 JBrowse link 12 21,264,600 21,403,663 RGD:6480464
G SLCO1B1 solute carrier organic anion transporter family member 1B1 JBrowse link 12 21,131,194 21,239,796 RGD:6480464
G SLCO1B3 solute carrier organic anion transporter family member 1B3 JBrowse link 12 20,810,705 20,916,911 RGD:6480464
G SLCO2B1 solute carrier organic anion transporter family member 2B1 JBrowse link 11 75,151,107 75,206,549 RGD:6480464
G SOD3 superoxide dismutase 3 JBrowse link 4 24,795,478 24,800,845 RGD:6480464
G SQSTM1 sequestosome 1 JBrowse link 5 179,806,393 179,838,078 RGD:6480464
G SRC SRC proto-oncogene, non-receptor tyrosine kinase JBrowse link 20 37,344,685 37,405,432 RGD:6480464
G STMN1 stathmin 1 JBrowse link 1 25,884,179 25,906,877 RGD:6480464
G SULT1A1 sulfotransferase family 1A member 1 JBrowse link 16 28,605,587 28,623,586 RGD:6480464
G SULT1D1P sulfotransferase family 1D member 1, pseudogene JBrowse link 4 69,791,873 69,813,872 RGD:6480464
G SULT2A1 sulfotransferase family 2A member 1 JBrowse link 19 47,870,467 47,886,315 RGD:6480464
G TFRC transferrin receptor JBrowse link 3 196,018,694 196,082,123 RGD:6480464
G TNF tumor necrosis factor JBrowse link 6 31,575,565 31,578,336 RGD:6480464
G VDR vitamin D receptor JBrowse link 12 47,841,537 47,905,022 RGD:6480464
G VEGFA vascular endothelial growth factor A JBrowse link 6 43,770,209 43,786,487 RGD:6480464
glycocholic acid term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G ABCB11 ATP binding cassette subfamily B member 11 JBrowse link 2 168,915,468 169,031,396 RGD:6480464
G ABCC1 ATP binding cassette subfamily C member 1 JBrowse link 16 15,949,616 16,143,062 RGD:6480464
G IL10 interleukin 10 JBrowse link 1 206,767,602 206,772,494 RGD:6480464
G NR1H4 nuclear receptor subfamily 1 group H member 4 JBrowse link 12 100,473,866 100,564,414 RGD:6480464
G POR cytochrome p450 oxidoreductase JBrowse link 7 75,915,155 75,986,855 RGD:6480464
G SLCO1B1 solute carrier organic anion transporter family member 1B1 JBrowse link 12 21,131,194 21,239,796 RGD:6480464
G SOD2 superoxide dismutase 2 JBrowse link 6 159,669,069 159,762,281 RGD:6480464
hyodeoxycholic acid term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G CYP2D6 cytochrome P450 family 2 subfamily D member 6 JBrowse link 22 42,126,499 42,130,810 RGD:6480464
G CYP3A4 cytochrome P450 family 3 subfamily A member 4 JBrowse link 7 99,756,967 99,784,184 RGD:6480464
G HSD11B1 hydroxysteroid 11-beta dehydrogenase 1 JBrowse link 1 209,686,180 209,734,950 RGD:6480464
G UGT2B4 UDP glucuronosyltransferase family 2 member B4 JBrowse link 4 69,480,165 69,526,014 RGD:6480464
G UGT2B7 UDP glucuronosyltransferase family 2 member B7 JBrowse link 4 69,051,264 69,112,987 RGD:6480464
sodium cholate term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G ALB albumin JBrowse link 4 73,404,287 73,421,482 RGD:6480464
G ALPL alkaline phosphatase, biomineralization associated JBrowse link 1 21,508,984 21,578,412 RGD:6480464
G BAX BCL2 associated X, apoptosis regulator JBrowse link 19 48,954,825 48,961,798 RGD:6480464
G BCL2 BCL2 apoptosis regulator JBrowse link 18 63,123,346 63,320,280 RGD:6480464
G CASP3 caspase 3 JBrowse link 4 184,627,696 184,649,475 RGD:6480464
G CCL2 C-C motif chemokine ligand 2 JBrowse link 17 34,255,285 34,257,203 RGD:6480464
G CCL5 C-C motif chemokine ligand 5 JBrowse link 17 35,871,491 35,880,360 RGD:6480464
G CCND1 cyclin D1 JBrowse link 11 69,641,156 69,654,474 RGD:6480464
G CES1 carboxylesterase 1 JBrowse link 16 55,802,851 55,833,127 RGD:6480464
G CST3 cystatin C JBrowse link 20 23,626,706 23,637,955 RGD:6480464
G CYBB cytochrome b-245 beta chain JBrowse link X 37,780,059 37,813,461 RGD:6480464
G CYP3A4 cytochrome P450 family 3 subfamily A member 4 JBrowse link 7 99,756,967 99,784,184 RGD:6480464
G CYP7A1 cytochrome P450 family 7 subfamily A member 1 JBrowse link 8 58,490,178 58,500,163 RGD:6480464
G FABP1 fatty acid binding protein 1 JBrowse link 2 88,122,982 88,128,062 RGD:6480464
G GCLC glutamate-cysteine ligase catalytic subunit JBrowse link 6 53,497,341 53,545,101 RGD:6480464
G GPX2 glutathione peroxidase 2 JBrowse link 14 64,939,158 64,942,745 RGD:6480464
G HAVCR1 hepatitis A virus cellular receptor 1 JBrowse link 5 157,028,383 157,069,633 RGD:6480464
G HIF1A hypoxia inducible factor 1 subunit alpha JBrowse link 14 61,695,513 61,748,259 RGD:6480464
G HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase JBrowse link 5 75,336,334 75,362,116 RGD:6480464
G HMOX1 heme oxygenase 1 JBrowse link 22 35,381,096 35,394,207 RGD:6480464
G ICAM1 intercellular adhesion molecule 1 JBrowse link 19 10,271,120 10,286,615 RGD:6480464
G IL1B interleukin 1 beta JBrowse link 2 112,829,751 112,836,843 RGD:6480464
G MAPK1 mitogen-activated protein kinase 1 JBrowse link 22 21,759,657 21,867,680 RGD:6480464
G MAPK3 mitogen-activated protein kinase 3 JBrowse link 16 30,114,105 30,123,309 RGD:6480464
G MET MET proto-oncogene, receptor tyrosine kinase JBrowse link 7 116,672,196 116,798,386 RGD:6480464
G NAGLU N-acetyl-alpha-glucosaminidase JBrowse link 17 42,534,238 42,544,449 RGD:6480464
G NFE2L2 nuclear factor, erythroid 2 like 2 JBrowse link 2 177,230,303 177,265,131 RGD:6480464
G NPHS1 NPHS1 adhesion molecule, nephrin JBrowse link 19 35,825,372 35,851,993 RGD:6480464
G NR1H3 nuclear receptor subfamily 1 group H member 3 JBrowse link 11 47,248,300 47,269,033 RGD:6480464
G NR1I3 nuclear receptor subfamily 1 group I member 3 JBrowse link 1 161,229,666 161,238,623 RGD:6480464
G PPARA peroxisome proliferator activated receptor alpha JBrowse link 22 46,150,526 46,243,756 RGD:6480464
G RARA retinoic acid receptor alpha JBrowse link 17 40,309,180 40,357,643 RGD:6480464
G S100A8 S100 calcium binding protein A8 JBrowse link 1 153,390,032 153,422,583 RGD:6480464
G SAA3P serum amyloid A3, pseudogene JBrowse link 11 18,112,472 18,116,132 RGD:6480464
G SOAT2 sterol O-acyltransferase 2 JBrowse link 12 53,103,486 53,124,535 RGD:6480464
G SOD2 superoxide dismutase 2 JBrowse link 6 159,669,069 159,762,281 RGD:6480464
G SREBF1 sterol regulatory element binding transcription factor 1 JBrowse link 17 17,811,334 17,837,017 RGD:6480464
G TGFB1 transforming growth factor beta 1 JBrowse link 19 41,330,323 41,353,922 RGD:6480464
G TLR4 toll like receptor 4 JBrowse link 9 117,704,403 117,724,735 RGD:6480464
G TNF tumor necrosis factor JBrowse link 6 31,575,565 31,578,336 RGD:6480464
G TP53 tumor protein p53 JBrowse link 17 7,668,402 7,687,550 RGD:6480464
G VCAM1 vascular cell adhesion molecule 1 JBrowse link 1 100,719,640 100,739,045 RGD:6480464
taurocholic acid term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G ABCA8 ATP binding cassette subfamily A member 8 JBrowse link 17 68,867,285 68,955,415 RGD:6480464
G ABCB1 ATP binding cassette subfamily B member 1 JBrowse link 7 87,503,017 87,713,323 RGD:6480464
G ABCB11 ATP binding cassette subfamily B member 11 JBrowse link 2 168,915,468 169,031,396 RGD:6480464
G ABCB4 ATP binding cassette subfamily B member 4 JBrowse link 7 87,398,988 87,476,722 RGD:6480464
G ABCC1 ATP binding cassette subfamily C member 1 JBrowse link 16 15,949,616 16,143,062 RGD:6480464
G ABCC2 ATP binding cassette subfamily C member 2 JBrowse link 10 99,782,602 99,853,741 RGD:6480464
G ABCC3 ATP binding cassette subfamily C member 3 JBrowse link 17 50,634,881 50,692,253 RGD:6480464
G ABCG2 ATP binding cassette subfamily G member 2 (Junior blood group) JBrowse link 4 88,090,264 88,231,626 RGD:6480464
G AHR aryl hydrocarbon receptor JBrowse link 7 17,298,652 17,346,147 RGD:6480464
G AKT1 AKT serine/threonine kinase 1 JBrowse link 14 104,769,349 104,795,748 RGD:6480464
G APOA1 apolipoprotein A1 JBrowse link 11 116,835,751 116,837,950 RGD:6480464
G APOA4 apolipoprotein A4 JBrowse link 11 116,820,700 116,823,304 RGD:6480464
G APOE apolipoprotein E JBrowse link 19 44,905,796 44,909,395 RGD:6480464
G BCL2 BCL2 apoptosis regulator JBrowse link 18 63,123,346 63,320,280 RGD:6480464
G BLVRA biliverdin reductase A JBrowse link 7 43,758,122 43,807,342 RGD:6480464
G BNIP3L BCL2 interacting protein 3 like JBrowse link 8 26,383,054 26,413,127 RGD:6480464
G CASP3 caspase 3 JBrowse link 4 184,627,696 184,649,475 RGD:6480464
G CASP8 caspase 8 JBrowse link 2 201,233,443 201,287,711 RGD:6480464
G CASP9 caspase 9 JBrowse link 1 15,491,401 15,524,912 RGD:6480464
G CAV1 caveolin 1 JBrowse link 7 116,525,009 116,561,185 RGD:6480464
G CAV2 caveolin 2 JBrowse link 7 116,499,738 116,508,541 RGD:6480464
G CCL2 C-C motif chemokine ligand 2 JBrowse link 17 34,255,285 34,257,203 RGD:6480464
G CCL20 C-C motif chemokine ligand 20 JBrowse link 2 227,813,842 227,817,556 RGD:6480464
G CCL3 C-C motif chemokine ligand 3 JBrowse link 17 36,088,256 36,090,143 RGD:6480464
G CCL4 C-C motif chemokine ligand 4 JBrowse link 17 36,103,827 36,105,614 RGD:6480464
G CCL5 C-C motif chemokine ligand 5 JBrowse link 17 35,871,491 35,880,360 RGD:6480464
G CCL7 C-C motif chemokine ligand 7 JBrowse link 17 34,270,221 34,272,242 RGD:6480464
G CCND1 cyclin D1 JBrowse link 11 69,641,156 69,654,474 RGD:6480464
G CCNE1 cyclin E1 JBrowse link 19 29,811,991 29,824,312 RGD:6480464
G CEL carboxyl ester lipase JBrowse link 9 133,061,981 133,071,861 RGD:6480464
G CFTR CF transmembrane conductance regulator JBrowse link 7 117,480,025 117,668,665 RGD:6480464
G CSF2 colony stimulating factor 2 JBrowse link 5 132,073,789 132,076,170 RGD:6480464
G CSF3 colony stimulating factor 3 JBrowse link 17 40,015,440 40,017,813 RGD:6480464
G CXCL1 C-X-C motif chemokine ligand 1 JBrowse link 4 73,869,393 73,871,308 RGD:6480464
G CXCL10 C-X-C motif chemokine ligand 10 JBrowse link 4 76,021,118 76,023,497 RGD:6480464
G CXCL11 C-X-C motif chemokine ligand 11 JBrowse link 4 76,033,682 76,036,070 RGD:6480464
G CXCL13 C-X-C motif chemokine ligand 13 JBrowse link 4 77,511,753 77,611,834 RGD:6480464
G CXCL16 C-X-C motif chemokine ligand 16 JBrowse link 17 4,733,533 4,739,928 RGD:6480464
G CXCL2 C-X-C motif chemokine ligand 2 JBrowse link 4 74,097,040 74,099,195 RGD:6480464
G CXCL6 C-X-C motif chemokine ligand 6 JBrowse link 4 73,836,678 73,838,760 RGD:6480464
G CYP27A1 cytochrome P450 family 27 subfamily A member 1 JBrowse link 2 218,781,733 218,815,293 RGD:6480464
G CYP7A1 cytochrome P450 family 7 subfamily A member 1 JBrowse link 8 58,490,178 58,500,163 RGD:6480464
G CYP7B1 cytochrome P450 family 7 subfamily B member 1 JBrowse link 8 64,586,575 64,798,737 RGD:6480464
G EGFR epidermal growth factor receptor JBrowse link 7 55,019,017 55,211,628 RGD:6480464
G EGR1 early growth response 1 JBrowse link 5 138,465,479 138,469,303 RGD:6480464
G FECH ferrochelatase JBrowse link 18 57,544,377 57,586,708 RGD:6480464
G FGF19 fibroblast growth factor 19 JBrowse link 11 69,698,238 69,704,022 RGD:6480464
G FGFR4 fibroblast growth factor receptor 4 JBrowse link 5 177,086,915 177,098,144 RGD:6480464
G HGF hepatocyte growth factor JBrowse link 7 81,699,006 81,770,438 RGD:6480464
G HNF4A hepatocyte nuclear factor 4 alpha JBrowse link 20 44,355,699 44,434,596 RGD:6480464
G ICAM1 intercellular adhesion molecule 1 JBrowse link 19 10,271,120 10,286,615 RGD:6480464
G IL10 interleukin 10 JBrowse link 1 206,767,602 206,772,494 RGD:6480464
G IL1B interleukin 1 beta JBrowse link 2 112,829,751 112,836,843 RGD:6480464
G IL6 interleukin 6 JBrowse link 7 22,725,889 22,732,002 RGD:6480464
G KL klotho JBrowse link 13 33,016,063 33,066,143 RGD:6480464
G KLF4 Kruppel like factor 4 JBrowse link 9 107,484,852 107,489,769 RGD:6480464
G MAP1LC3B microtubule associated protein 1 light chain 3 beta JBrowse link 16 87,392,336 87,404,774 RGD:6480464
G MAPK1 mitogen-activated protein kinase 1 JBrowse link 22 21,759,657 21,867,680 RGD:6480464
G MAPK3 mitogen-activated protein kinase 3 JBrowse link 16 30,114,105 30,123,309 RGD:6480464
G MAPK8 mitogen-activated protein kinase 8 JBrowse link 10 48,306,639 48,439,360 RGD:6480464
G MAPK9 mitogen-activated protein kinase 9 JBrowse link 5 180,233,143 180,292,083 RGD:6480464
G MIR1178 microRNA 1178 JBrowse link 12 119,713,634 119,713,724 RGD:6480464
G MIR4717 microRNA 4717 JBrowse link 16 2,274,620 2,274,691 RGD:6480464
G MIR488 microRNA 488 JBrowse link 1 177,029,363 177,029,445 RGD:6480464
G MIR590 microRNA 590 JBrowse link 7 74,191,198 74,191,294 RGD:6480464
G MMP2 matrix metallopeptidase 2 JBrowse link 16 55,478,830 55,506,691 RGD:6480464
G MMP9 matrix metallopeptidase 9 JBrowse link 20 46,008,908 46,016,561 RGD:6480464
G MPO myeloperoxidase JBrowse link 17 58,269,855 58,280,935 RGD:6480464
G MYC MYC proto-oncogene, bHLH transcription factor JBrowse link 8 127,735,434 127,742,951 RGD:6480464
G NANOG Nanog homeobox JBrowse link 12 7,789,402 7,799,146 RGD:6480464
G NFE2L2 nuclear factor, erythroid 2 like 2 JBrowse link 2 177,230,303 177,265,131 RGD:6480464
G NFKBIA NFKB inhibitor alpha JBrowse link 14 35,401,513 35,404,749 RGD:6480464
G NFKBIB NFKB inhibitor beta JBrowse link 19 38,899,503 38,908,894 RGD:6480464
G NOS2 nitric oxide synthase 2 JBrowse link 17 27,756,766 27,800,529 RGD:6480464
G NR0B2 nuclear receptor subfamily 0 group B member 2 JBrowse link 1 26,911,489 26,914,110 RGD:6480464
G NR1H4 nuclear receptor subfamily 1 group H member 4 JBrowse link 12 100,473,866 100,564,414 RGD:6480464
G NR1I2 nuclear receptor subfamily 1 group I member 2 JBrowse link 3 119,780,484 119,818,485 RGD:6480464
G NR1I3 nuclear receptor subfamily 1 group I member 3 JBrowse link 1 161,229,666 161,238,623 RGD:6480464
G PNLIP pancreatic lipase JBrowse link 10 116,545,931 116,567,855 RGD:6480464
G PON1 paraoxonase 1 JBrowse link 7 95,297,676 95,324,532 RGD:6480464
G POR cytochrome p450 oxidoreductase JBrowse link 7 75,915,155 75,986,855 RGD:6480464
G POU5F1 POU class 5 homeobox 1 JBrowse link 6 31,164,337 31,170,682 RGD:6480464
G PPARA peroxisome proliferator activated receptor alpha JBrowse link 22 46,150,526 46,243,756 RGD:6480464
G PTGS2 prostaglandin-endoperoxide synthase 2 JBrowse link 1 186,671,791 186,680,423 RGD:6480464
G RAB7A RAB7A, member RAS oncogene family JBrowse link 3 128,726,183 128,814,798 RGD:6480464
G RELA RELA proto-oncogene, NF-kB subunit JBrowse link 11 65,653,596 65,662,972 RGD:6480464
G S1PR2 sphingosine-1-phosphate receptor 2 JBrowse link 19 10,221,433 10,231,331 RGD:6480464
G SERPINE1 serpin family E member 1 JBrowse link 7 101,127,104 101,139,247 RGD:6480464
G SLC10A1 solute carrier family 10 member 1 JBrowse link 14 69,775,416 69,797,241 RGD:6480464
G SLC10A2 solute carrier family 10 member 2 JBrowse link 13 103,043,998 103,066,417 RGD:6480464
G SLC19A1 solute carrier family 19 member 1 JBrowse link 21 45,502,517 45,563,140 RGD:6480464
G SLC22A6 solute carrier family 22 member 6 JBrowse link 11 62,976,597 62,984,967 RGD:6480464
G SLC22A8 solute carrier family 22 member 8 JBrowse link 11 62,992,824 63,015,845 RGD:6480464
G SLC23A1 solute carrier family 23 member 1 JBrowse link 5 139,367,196 139,384,553 RGD:6480464
G SLC23A2 solute carrier family 23 member 2 JBrowse link 20 4,852,358 5,010,313 RGD:6480464
G SLCO1A2 solute carrier organic anion transporter family member 1A2 JBrowse link 12 21,264,600 21,403,663 RGD:6480464
G SLCO1B1 solute carrier organic anion transporter family member 1B1 JBrowse link 12 21,131,194 21,239,796 RGD:6480464
G SLCO1B3 solute carrier organic anion transporter family member 1B3 JBrowse link 12 20,810,705 20,916,911 RGD:6480464
G SLCO2B1 solute carrier organic anion transporter family member 2B1 JBrowse link 11 75,151,107 75,206,549 RGD:6480464
G SOD1 superoxide dismutase 1 JBrowse link 21 31,659,693 31,668,931 RGD:6480464
G SOD2 superoxide dismutase 2 JBrowse link 6 159,669,069 159,762,281 RGD:6480464
G SORT1 sortilin 1 JBrowse link 1 109,309,565 109,397,940 RGD:6480464
G SOX2 SRY-box transcription factor 2 JBrowse link 3 181,711,925 181,714,436 RGD:6480464
G SQSTM1 sequestosome 1 JBrowse link 5 179,806,393 179,838,078 RGD:6480464
G STAT1 signal transducer and activator of transcription 1 JBrowse link 2 190,968,989 191,014,250 RGD:6480464
G STAT3 signal transducer and activator of transcription 3 JBrowse link 17 42,313,324 42,388,502 RGD:6480464
G TNF tumor necrosis factor JBrowse link 6 31,575,565 31,578,336 RGD:6480464
G VCAM1 vascular cell adhesion molecule 1 JBrowse link 1 100,719,640 100,739,045 RGD:6480464

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 23754
    chemical entity 23717
      molecular entity 23664
        polyatomic entity 23570
          heteroatomic molecular entity 23132
            hydroxides 21977
              organic hydroxy compound 20327
                hydroxy-5beta-cholanic acid 902
                  trihydroxy-5beta-cholanic acid 194
                    cholic acid 193
                      (23S)-methyl-3alpha,7alpha,12alpha-trihydroxy-5beta-cholan-24-oic acid 0
                      3-[(3-cholamidopropyl)dimethylammonio]propane-1-sulfonate 0
                      N-(2-phosphonoethyl)cholamide 0
                      S-choloyl-4'-phosphopantetheine 0
                      cholate salt + 42
                      cholic acid 24-O-(beta-D-glucuronide) 0
                      choloyl-CoA 0
                      glycochenodeoxycholic acid 7-sulfate 0
                      glycocholic acid 7
                      hyodeoxycholic acid + 5
                      murideoxycholic acid 0
                      taurocholic acid 108
                      taurohyocholic acid 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 23754
    subatomic particle 23703
      composite particle 23703
        hadron 23703
          baryon 23703
            nucleon 23703
              atomic nucleus 23703
                atom 23703
                  main group element atom 23522
                    p-block element atom 23522
                      carbon group element atom 23232
                        carbon atom 23208
                          organic molecular entity 23208
                            organic molecule 23069
                              organic cyclic compound 22083
                                organic polycyclic compound 17315
                                  steroid 13506
                                    steroid fundamental parent 13099
                                      cholane 902
                                        cholanoid 902
                                          cholanic acids 902
                                            cholanic acid 902
                                              5beta-cholanic acid 902
                                                hydroxy-5beta-cholanic acid 902
                                                  trihydroxy-5beta-cholanic acid 194
                                                    cholic acid 193
                                                      (23S)-methyl-3alpha,7alpha,12alpha-trihydroxy-5beta-cholan-24-oic acid 0
                                                      3-[(3-cholamidopropyl)dimethylammonio]propane-1-sulfonate 0
                                                      N-(2-phosphonoethyl)cholamide 0
                                                      S-choloyl-4'-phosphopantetheine 0
                                                      cholate salt + 42
                                                      cholic acid 24-O-(beta-D-glucuronide) 0
                                                      choloyl-CoA 0
                                                      glycochenodeoxycholic acid 7-sulfate 0
                                                      glycocholic acid 7
                                                      hyodeoxycholic acid + 5
                                                      murideoxycholic acid 0
                                                      taurocholic acid 108
                                                      taurohyocholic acid 0
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.