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G |
Agt |
angiotensinogen |
increases abundance |
EXP |
AGT protein results in increased abundance of Phosphatidic Acids |
CTD |
PMID:14613874 |
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NCBI chr19:57,321,594...57,333,460
Ensembl chr19:57,321,640...57,333,433
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G |
Akt1 |
AKT serine/threonine kinase 1 |
multiple interactions |
ISO EXP |
alpha-cyano-(3,4-dihydroxy)-N-benzylcinnamide inhibits the reaction [Phosphatidic Acids results in increased phosphorylation of AKT1 protein] R 59949 inhibits the reaction [Phosphatidic Acids results in increased phosphorylation of AKT1 protein] |
CTD |
PMID:15525798 PMID:16354768 |
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NCBI chr 6:137,218,398...137,239,970
Ensembl chr 6:137,218,376...137,236,258
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G |
Avp |
arginine vasopressin |
increases abundance multiple interactions |
EXP |
AVP protein results in increased abundance of Phosphatidic Acids 2-(4-amylcinnamoyl)amino-4-chlorobenzoic acid inhibits the reaction [AVP protein results in increased abundance of Phosphatidic Acids] |
CTD |
PMID:11356622 |
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NCBI chr 3:123,117,482...123,119,460
Ensembl chr 3:123,117,492...123,119,460
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G |
Bglap |
bone gamma-carboxyglutamate protein |
increases activity |
ISO |
Phosphatidic Acids results in increased activity of BGLAP protein |
CTD |
PMID:16857255 |
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NCBI chr 2:187,741,770...187,748,445
Ensembl chr 2:187,741,770...187,742,747
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G |
Egf |
epidermal growth factor |
multiple interactions increases abundance |
EXP |
1-Butanol inhibits the reaction [EGF protein results in increased abundance of Phosphatidic Acids] |
CTD |
PMID:11134345 |
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NCBI chr 2:68,820,616...68,895,537
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G |
Fgr |
FGR proto-oncogene, Src family tyrosine kinase |
increases activity |
ISO |
Phosphatidic Acids results in increased activity of FGR protein |
CTD |
PMID:11078731 |
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NCBI chr 5:151,172,189...151,199,746
Ensembl chr 5:151,172,206...151,199,745
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G |
Il1b |
interleukin 1 beta |
multiple interactions increases secretion |
ISO |
alpha-cyano-(3,4-dihydroxy)-N-benzylcinnamide inhibits the reaction [Phosphatidic Acids results in increased secretion of IL1B protein] |
CTD |
PMID:16354768 |
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NCBI chr 3:121,876,256...121,882,637
Ensembl chr 3:121,876,263...121,882,726
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G |
Il6 |
interleukin 6 |
multiple interactions increases secretion |
ISO |
alpha-cyano-(3,4-dihydroxy)-N-benzylcinnamide inhibits the reaction [Phosphatidic Acids results in increased secretion of IL6 protein] |
CTD |
PMID:16354768 |
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NCBI chr 4:3,043,231...3,047,807
Ensembl chr 4:3,043,231...3,047,807
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G |
Jak2 |
Janus kinase 2 |
increases phosphorylation |
ISO |
Phosphatidic Acids results in increased phosphorylation of JAK2 protein |
CTD |
PMID:16354768 |
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NCBI chr 1:247,398,667...247,457,521
Ensembl chr 1:247,398,598...247,458,509
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G |
Mapk1 |
mitogen activated protein kinase 1 |
multiple interactions |
ISO |
Phosphatidic Acids inhibits the reaction [Ethanol results in decreased phosphorylation of and results in decreased activity of MAPK1 protein]; Phosphatidic Acids results in increased phosphorylation of and results in increased activity of MAPK1 protein; U 0126 inhibits the reaction [Phosphatidic Acids results in increased phosphorylation of and results in increased activity of MAPK1 protein] |
CTD |
PMID:18358832 |
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NCBI chr11:88,203,863...88,273,301
Ensembl chr11:88,211,599...88,273,254
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G |
Mapk3 |
mitogen activated protein kinase 3 |
multiple interactions |
ISO |
Phosphatidic Acids inhibits the reaction [Ethanol results in decreased phosphorylation of and results in decreased activity of MAPK3 protein]; Phosphatidic Acids results in increased phosphorylation of and results in increased activity of MAPK3 protein; U 0126 inhibits the reaction [Phosphatidic Acids results in increased phosphorylation of and results in increased activity of MAPK3 protein] |
CTD |
PMID:18358832 |
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NCBI chr 1:198,192,773...198,198,975
Ensembl chr 1:198,192,773...198,198,975
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G |
Mmp2 |
matrix metallopeptidase 2 |
increases activity multiple interactions |
ISO |
Phosphatidic Acids results in increased activity of MMP2 protein Quercetin inhibits the reaction [Phosphatidic Acids results in increased activity of MMP2 protein] |
CTD |
PMID:21867678 |
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NCBI chr19:15,542,771...15,570,589
Ensembl chr19:15,542,765...15,570,611
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G |
Mtor |
mechanistic target of rapamycin kinase |
multiple interactions increases activity |
ISO |
MTOR protein affects the reaction [Phosphatidic Acids results in increased activity of RPS6KB2 protein] Phosphatidic Acids results in increased activity of MTOR protein |
CTD |
PMID:12087098 PMID:16537399 |
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NCBI chr 5:165,263,813...165,373,967
Ensembl chr 5:165,263,800...165,373,967
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G |
Oprm1 |
opioid receptor, mu 1 |
multiple interactions |
EXP |
[1-Butanol inhibits the reaction [PLD2 protein results in increased chemical synthesis of Phosphatidic Acids]] affects the reaction [PENK protein binds to and results in increased activity of OPRM1 protein] |
CTD |
PMID:14720217 |
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NCBI chr 1:43,454,803...43,704,948
Ensembl chr 1:43,454,803...43,704,948
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G |
Penk |
proenkephalin |
multiple interactions |
EXP |
[1-Butanol inhibits the reaction [PLD2 protein results in increased chemical synthesis of Phosphatidic Acids]] affects the reaction [PENK protein binds to and results in increased activity of OPRM1 protein] |
CTD |
PMID:14720217 |
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NCBI chr 5:17,056,412...17,061,762
Ensembl chr 5:17,056,419...17,061,837
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G |
Pld1 |
phospholipase D1 |
increases activity |
ISO |
Phosphatidic Acids results in increased activity of PLD1 protein |
CTD |
PMID:16857255 |
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NCBI chr 2:113,651,967...113,849,403
Ensembl chr 2:113,652,348...113,849,403
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G |
Pld2 |
phospholipase D2 |
multiple interactions |
EXP |
1-Butanol inhibits the reaction [PLD2 protein results in increased chemical synthesis of Phosphatidic Acids]; [1-Butanol inhibits the reaction [PLD2 protein results in increased chemical synthesis of Phosphatidic Acids]] affects the reaction [PENK protein binds to and results in increased activity of OPRM1 protein] |
CTD |
PMID:14720217 |
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NCBI chr10:57,161,921...57,181,148
Ensembl chr10:57,163,174...57,179,730
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G |
Prkcz |
protein kinase C, zeta |
increases activity multiple interactions |
EXP ISO |
Phosphatidic Acids results in increased activity of PRKCZ protein Phosphatidic Acids results in increased phosphorylation of and results in increased activity of PRKCZ protein |
CTD |
PMID:11978788 PMID:15255942 |
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NCBI chr 5:172,658,071...172,769,492
Ensembl chr 5:172,658,748...172,769,421
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G |
Ptgs2 |
prostaglandin-endoperoxide synthase 2 |
increases expression |
ISO |
Phosphatidic Acids results in increased expression of PTGS2 protein Phosphatidic Acids results in increased expression of PTGS2 mRNA |
CTD |
PMID:12872987 PMID:15210717 |
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NCBI chr13:67,351,230...67,356,920
Ensembl chr13:67,351,087...67,359,335
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G |
Rps6kb1 |
ribosomal protein S6 kinase B1 |
multiple interactions |
ISO |
Phosphatidic Acids results in increased phosphorylation of and results in increased activity of RPS6KB1 protein |
CTD |
PMID:15255942 |
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NCBI chr10:73,824,200...73,865,503
Ensembl chr10:73,824,202...73,865,364
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G |
Rps6kb2 |
ribosomal protein S6 kinase B2 |
multiple interactions increases activity |
ISO |
MTOR protein affects the reaction [Phosphatidic Acids results in increased activity of RPS6KB2 protein]; Sirolimus inhibits the reaction [Phosphatidic Acids results in increased activity of RPS6KB2 protein]; wortmannin inhibits the reaction [Phosphatidic Acids results in increased activity of RPS6KB2 protein] |
CTD |
PMID:12087098 |
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NCBI chr 1:219,406,201...219,412,888
Ensembl chr 1:219,406,202...219,412,888
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G |
Stat1 |
signal transducer and activator of transcription 1 |
multiple interactions |
ISO |
Phosphatidic Acids results in increased phosphorylation of and affects the localization of STAT1 protein |
CTD |
PMID:16354768 |
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NCBI chr 9:54,287,540...54,327,958
Ensembl chr 9:54,287,541...54,484,533
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G |
Stat3 |
signal transducer and activator of transcription 3 |
multiple interactions |
ISO |
Phosphatidic Acids results in increased phosphorylation of and affects the localization of STAT3 protein |
CTD |
PMID:16354768 |
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NCBI chr10:88,790,401...88,842,263
Ensembl chr10:88,790,408...88,842,233
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G |
Sts |
steroid sulfatase |
multiple interactions |
ISO |
Phosphatidic Acids promotes the reaction [Tretinoin results in increased activity of STS protein] |
CTD |
PMID:16178010 |
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NCBI chr X:45,420,418...45,428,748
Ensembl chr X:45,420,596...45,428,750
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G |
Tnf |
tumor necrosis factor |
multiple interactions increases secretion |
ISO |
TNF protein inhibits the reaction [Carbachol results in increased abundance of Phosphatidic Acids] Phosphatidic Acids results in increased secretion of TNF protein |
CTD |
PMID:11245595 PMID:16354768 |
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NCBI chr20:5,189,382...5,192,000
Ensembl chr20:5,189,390...5,192,000
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G |
Ptgs2 |
prostaglandin-endoperoxide synthase 2 |
increases expression |
ISO |
dioctanoylphosphatidic acid results in increased expression of PTGS2 protein |
CTD |
PMID:11854442 |
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NCBI chr13:67,351,230...67,356,920
Ensembl chr13:67,351,087...67,359,335
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G |
Plek |
pleckstrin |
multiple interactions |
ISO |
dioleoylphosphatidic acid analog promotes the reaction [Guanosine 5'-O-(3-Thiotriphosphate) results in increased phosphorylation of PLEK protein] |
CTD |
PMID:8928743 |
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NCBI chr14:100,151,518...100,184,192
Ensembl chr14:100,151,210...100,217,913
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G |
Plek |
pleckstrin |
multiple interactions |
ISO |
phosphatidylethanol analog promotes the reaction [Guanosine 5'-O-(3-Thiotriphosphate) results in increased phosphorylation of PLEK protein] |
CTD |
PMID:8928743 |
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NCBI chr14:100,151,518...100,184,192
Ensembl chr14:100,151,210...100,217,913
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