Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   

CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:adenosine
go back to main search page
Accession:CHEBI:16335 term browser browse the term
Definition:A ribonucleoside composed of a molecule of adenine attached to a ribofuranose moiety via a beta-N(9)-glycosidic bond.
Synonyms:related_synonym: (2R,3R,4S,5R)-2-(6-aminopurin-9-yl)-5-(hydroxymethyl)oxolane-3,4-diol;   6-Amino-9-beta-D-ribofuranosyl-9H-purine;   9-beta-D-Ribofuranosidoadenine;   9-beta-D-ribofuranosyl-9H-purin-6-amine;   Ade-Rib;   Adenine Deoxyribonucleoside;   Adenocard;   Adenocor;   Adenoscan;   Adenosin;   Adenyldeoxyriboside;   Ado;   Deoxyadenosine;   Desoxyadenosine;   Formula=C10H13N5O4;   InChI=1S/C10H13N5O4/c11-8-5-9(13-2-12-8)15(3-14-5)10-7(18)6(17)4(1-16)19-10/h2-4,6-7,10,16-18H,1H2,(H2,11,12,13)/t4-,6-,7-,10-/m1/s1;   InChIKey=OIRDTQYFTABQOQ-KQYNXXCUSA-N;   SMILES=Nc1ncnc2n(cnc12)[C@@H]1O[C@H](CO)[C@@H](O)[C@H]1O;   beta-D-Adenosine
 alt_id: CHEBI:13734;   CHEBI:22237;   CHEBI:2472;   CHEBI:40558;   CHEBI:40825;   CHEBI:40906
 xref: Beilstein:93029;   CAS:58-61-7;   DrugBank:DB00640;   Drug_Central:90;   ECMDB:ECMDB00050;   Gmelin:53385;   HMDB:HMDB0000050;   KEGG:C00212;   KEGG:D00045;   KNApSAcK:C00007444;   LINCS:LSM-28568
 xref_mesh: MESH:D000241
 xref: MetaCyc:ADENOSINE;   PDBeChem:ADN;   PMID:11213237;   PMID:11820865;   PMID:11978011;   PMID:16183671;   PMID:16917093;   PMID:17190852;   PMID:18000974;   PMID:323854;   Reaxys:93029;   Wikipedia:Adenosine;   YMDB:YMDB00058


show annotations for term's descendants           Sort by:
 
adenosine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G MYL9 myosin light chain 9 decreases phosphorylation
multiple interactions
EXP Adenosine results in decreased phosphorylation of MYL9 protein
8-phenyltheophylline inhibits the reaction [Adenosine results in decreased phosphorylation of MYL9 protein]
CTD PMID:10942722 NCBI chr17:39,788,165...39,795,240
Ensembl chr17:39,788,199...39,795,296
JBrowse link
ATP term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BCL2 BCL2 apoptosis regulator multiple interactions
increases expression
EXP tetrakis(N-methyl-4-pyridiniumyl)porphine manganese(III) complex inhibits the reaction [Adenosine Triphosphate results in increased expression of BCL2 protein] CTD PMID:17997382 NCBI chr 1:158,337,403...158,518,214
Ensembl chr 1:158,288,544...158,518,879
JBrowse link
G CASP8 caspase 8 increases activity
multiple interactions
EXP Adenosine Triphosphate results in increased activity of CASP8 protein
tetrakis(N-methyl-4-pyridiniumyl)porphine manganese(III) complex inhibits the reaction [Adenosine Triphosphate results in increased activity of CASP8 protein]
CTD PMID:17997382 NCBI chr15:104,923,659...104,948,470
Ensembl chr15:104,923,953...104,948,470
JBrowse link
G CYCS cytochrome c, somatic affects localization
multiple interactions
EXP Adenosine Triphosphate affects the localization of CYCS protein
[Calcium co-treated with Phosphates co-treated with Adenosine Triphosphate] affects the localization of CYCS protein; tetrakis(N-methyl-4-pyridiniumyl)porphine manganese(III) complex inhibits the reaction [Adenosine Triphosphate affects the localization of CYCS protein]
CTD PMID:16489745 PMID:17997382 NCBI chr18:47,169,921...47,172,212
Ensembl chr18:47,169,866...47,173,866
JBrowse link
G MYL9 myosin light chain 9 decreases phosphorylation
multiple interactions
EXP Adenosine Triphosphate results in decreased phosphorylation of MYL9 protein
1,2-bis(2-aminophenoxy)ethane-N,N,N',N'-tetraacetic acid inhibits the reaction [Adenosine Triphosphate promotes the reaction [calyculin A results in increased phosphorylation of MYL9 protein]]; Adenosine Triphosphate promotes the reaction [calyculin A results in increased phosphorylation of MYL9 protein]
CTD PMID:10942722 NCBI chr17:39,788,165...39,795,240
Ensembl chr17:39,788,199...39,795,296
JBrowse link
G TNF tumor necrosis factor increases expression
multiple interactions
EXP Adenosine Triphosphate results in increased expression of TNF protein
tetrakis(N-methyl-4-pyridiniumyl)porphine manganese(III) complex inhibits the reaction [Adenosine Triphosphate results in increased expression of TNF protein]
CTD PMID:17997382 NCBI chr 7:23,699,635...23,702,393
Ensembl chr 7:23,699,636...23,703,655
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 880
    role 860
      biological role 860
        pharmacological role 385
          analgesic 26
            adenosine 5
              1-methyladenosine 0
              1-tuberculosinyladenosine(1+) 0
              2-methylthio-N(6)-(Delta(2)-isopentenyl)adenosine + 0
              2-methylthio-N(6)-(cis-4-hydroxy-Delta(2)-isopentenyl)adenosine + 0
              2-thio-N(6)-(Delta(2)-isopentenyl)adenosine + 0
              3'-O-salicyl-AMP 0
              3'-phosphoadenylyl selenate 0
              3-iodo-4-aminobenzyl-5'-N-methylcarboxamidoadenosine 0
              3-iodobenzyl-5'-N-methylcarboxamidoadenosine 0
              5'-O-sulfamoyladenosine 0
              5'-S-methyl-5'-thioadenosine 0
              5'-chloro-5'-deoxyadenosine 0
              5'-deoxyadenosine 0
              5'-ethylthioadenosine 0
              9-ribosyl-trans-zeatin 0
              CGS-21680 0
              L-adenosylselenohomocysteine 0
              N(6),N(6)-dimethyladenosine 0
              N(6)-(Delta(2)-isopentenyl)adenosine + 0
              N-[(9-beta-D-ribofuranosyl-2-methylthiopurin-6-yl)carbamoyl]threonine 0
              N-[(9-beta-D-ribofuranosylpurin-6-yl)carbamoyl]threonine 0
              N-ethyl-5'-carboxamidoadenosine 0
              adenosine phosphate + 5
              adenosine residue 0
              adenylyl selenate 0
              alpha-N-(9-beta-D-ribofuranosylpurin-6-yl)glycinamide 0
              aspartyl adenylate beta-ketophosphonate isostere 0
              cordysinin B 0
              diadenosyl diphosphate + 0
              diadenosyl hexaphosphate + 0
              diadenosyl pentaphosphate + 0
              diadenosyl tetraphosphate + 0
              diadenosyl triphosphate + 0
              nucleocidin 0
              propionyl adenylate 0
              sangivamycin 0
              succinyladenosine 0
              thioadenosine + 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 880
    subatomic particle 865
      composite particle 865
        hadron 865
          baryon 865
            nucleon 865
              atomic nucleus 865
                atom 865
                  main group element atom 855
                    p-block element atom 852
                      carbon group element atom 828
                        carbon atom 827
                          organic molecular entity 827
                            heteroorganic entity 582
                              organochalcogen compound 528
                                organooxygen compound 463
                                  carbohydrates and carbohydrate derivatives 110
                                    carbohydrate 110
                                      carbohydrate derivative 99
                                        glycosyl compound 40
                                          N-glycosyl compound 27
                                            nucleoside 27
                                              ribonucleoside 6
                                                purine ribonucleoside 6
                                                  purines D-ribonucleoside 5
                                                    adenosine 5
                                                      1-methyladenosine 0
                                                      1-tuberculosinyladenosine(1+) 0
                                                      2-methylthio-N(6)-(Delta(2)-isopentenyl)adenosine + 0
                                                      2-methylthio-N(6)-(cis-4-hydroxy-Delta(2)-isopentenyl)adenosine + 0
                                                      2-thio-N(6)-(Delta(2)-isopentenyl)adenosine + 0
                                                      3'-O-salicyl-AMP 0
                                                      3'-phosphoadenylyl selenate 0
                                                      3-iodo-4-aminobenzyl-5'-N-methylcarboxamidoadenosine 0
                                                      3-iodobenzyl-5'-N-methylcarboxamidoadenosine 0
                                                      5'-O-sulfamoyladenosine 0
                                                      5'-S-methyl-5'-thioadenosine 0
                                                      5'-chloro-5'-deoxyadenosine 0
                                                      5'-deoxyadenosine 0
                                                      5'-ethylthioadenosine 0
                                                      9-ribosyl-trans-zeatin 0
                                                      CGS-21680 0
                                                      L-adenosylselenohomocysteine 0
                                                      N(6),N(6)-dimethyladenosine 0
                                                      N(6)-(Delta(2)-isopentenyl)adenosine + 0
                                                      N-[(9-beta-D-ribofuranosyl-2-methylthiopurin-6-yl)carbamoyl]threonine 0
                                                      N-[(9-beta-D-ribofuranosylpurin-6-yl)carbamoyl]threonine 0
                                                      N-ethyl-5'-carboxamidoadenosine 0
                                                      adenosine phosphate + 5
                                                      adenosine residue 0
                                                      adenylyl selenate 0
                                                      alpha-N-(9-beta-D-ribofuranosylpurin-6-yl)glycinamide 0
                                                      aspartyl adenylate beta-ketophosphonate isostere 0
                                                      cordysinin B 0
                                                      diadenosyl diphosphate + 0
                                                      diadenosyl hexaphosphate + 0
                                                      diadenosyl pentaphosphate + 0
                                                      diadenosyl tetraphosphate + 0
                                                      diadenosyl triphosphate + 0
                                                      nucleocidin 0
                                                      propionyl adenylate 0
                                                      sangivamycin 0
                                                      succinyladenosine 0
                                                      thioadenosine + 0
paths to the root