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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:dCTP
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Accession:CHEBI:16311 term browser browse the term
Definition:A 2'-deoxycytidine phosphate having cytosine as the nucleobase.
Synonyms:exact_synonym: 2'-deoxycytidine 5'-(tetrahydrogen triphosphate)
 related_synonym: 2'-Deoxycytidine 5'-triphosphate;   Deoxycytidine 5'-triphosphate;   Deoxycytidine triphosphate;   Formula=C9H16N3O13P3;   InChI=1S/C9H16N3O13P3/c10-7-1-2-12(9(14)11-7)8-3-5(13)6(23-8)4-22-27(18,19)25-28(20,21)24-26(15,16)17/h1-2,5-6,8,13H,3-4H2,(H,18,19)(H,20,21)(H2,10,11,14)(H2,15,16,17)/t5-,6+,8+/m0/s1;   InChIKey=RGWHQCVHVJXOKC-SHYZEUOFSA-N;   SMILES=Nc1ccn([C@H]2C[C@H](O)[C@@H](COP(O)(=O)OP(O)(=O)OP(O)(O)=O)O2)c(=O)n1
 alt_id: CHEBI:10494;   CHEBI:14072;   CHEBI:19243
 xref: CAS:2056-98-6;   DrugBank:DB03258;   KEGG:C00458
 xref_mesh: MESH:C024107
 xref: PDBeChem:DCP
 cyclic_relationship: is_conjugate_acid_of CHEBI:57724


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dCTP term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dck deoxycytidine kinase increases metabolic processing
affects activity
ISO DCK protein results in increased metabolism of 2'-deoxycytidine 5'-triphosphate
2'-deoxycytidine 5'-triphosphate affects the activity of DCK protein
CTD PMID:9586059 NCBI chr14:20,935,442...20,952,939
Ensembl chr14:20,935,369...20,953,095
JBrowse link
G Polk DNA polymerase kappa multiple interactions
affects binding
ISO 2'-deoxycytidine 5'-triphosphate promotes the reaction [N(2)-furfuryl-deoxyguanosine results in increased stability of POLK protein]; N-(2'-deoxyguanosin-8-yl)-3-aminobenzanthrone inhibits the reaction [POLK protein binds to 2'-deoxycytidine 5'-triphosphate] CTD PMID:28823149 PMID:31286773 NCBI chr 2:27,305,718...27,364,906
Ensembl chr 2:27,305,728...27,364,906
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19781
    role 19726
      biological role 19726
        biochemical role 19319
          metabolite 19301
            prokaryotic metabolite 18392
              bacterial metabolite 18392
                Escherichia coli metabolite 18277
                  dCTP 2
                    5-iododeoxycytidine triphosphate 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19781
    subatomic particle 19779
      composite particle 19779
        hadron 19779
          baryon 19779
            nucleon 19779
              atomic nucleus 19779
                atom 19779
                  main group element atom 19669
                    p-block element atom 19669
                      chalcogen 19401
                        oxygen atom 19364
                          oxygen molecular entity 19364
                            hydroxides 19087
                              oxoacid 18318
                                pnictogen oxoacid 10313
                                  phosphorus oxoacid 9238
                                    phosphoric acids 7958
                                      phosphoric acid 7958
                                        phosphoric acid derivative 7639
                                          phosphate 7639
                                            organic phosphate 7638
                                              carbohydrate phosphate 1731
                                                phospho sugar 1656
                                                  aldose phosphate 1654
                                                    aldopentose phosphate 1648
                                                      deoxyaldopentose phosphate 9
                                                        2-deoxyribose phosphate 9
                                                          2'-deoxyribonucleotide 8
                                                            2'-deoxyribonucleoside 5'-phosphate 8
                                                              2'-deoxyribonucleoside 5'-triphosphate 3
                                                                pyrimidine 2'-deoxyribonucleoside 5'-triphosphate 2
                                                                  dCTP 2
                                                                    5-iododeoxycytidine triphosphate 0
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