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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:dCTP
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Accession:CHEBI:16311 term browser browse the term
Definition:A 2'-deoxycytidine phosphate having cytosine as the nucleobase.
Synonyms:exact_synonym: 2'-deoxycytidine 5'-(tetrahydrogen triphosphate)
 related_synonym: 2'-Deoxycytidine 5'-triphosphate;   Deoxycytidine 5'-triphosphate;   Deoxycytidine triphosphate;   Formula=C9H16N3O13P3;   InChI=1S/C9H16N3O13P3/c10-7-1-2-12(9(14)11-7)8-3-5(13)6(23-8)4-22-27(18,19)25-28(20,21)24-26(15,16)17/h1-2,5-6,8,13H,3-4H2,(H,18,19)(H,20,21)(H2,10,11,14)(H2,15,16,17)/t5-,6+,8+/m0/s1;   InChIKey=RGWHQCVHVJXOKC-SHYZEUOFSA-N;   SMILES=Nc1ccn([C@H]2C[C@H](O)[C@@H](COP(O)(=O)OP(O)(=O)OP(O)(O)=O)O2)c(=O)n1
 alt_id: CHEBI:10494;   CHEBI:14072;   CHEBI:19243
 xref: CAS:2056-98-6;   DrugBank:DB03258;   KEGG:C00458
 xref_mesh: MESH:C024107
 xref: PDBeChem:DCP
 cyclic_relationship: is_conjugate_acid_of CHEBI:57724


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dCTP term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dck deoxycytidine kinase increases metabolic processing
affects activity
ISO DCK protein results in increased metabolism of 2'-deoxycytidine 5'-triphosphate
2'-deoxycytidine 5'-triphosphate affects the activity of DCK protein
CTD PMID:9586059 NCBI chr14:20,935,442...20,952,939
Ensembl chr14:20,935,369...20,953,095
JBrowse link
G Polk DNA polymerase kappa multiple interactions
affects binding
ISO 2'-deoxycytidine 5'-triphosphate promotes the reaction [N(2)-furfuryl-deoxyguanosine results in increased stability of POLK protein]; N-(2'-deoxyguanosin-8-yl)-3-aminobenzanthrone inhibits the reaction [POLK protein binds to 2'-deoxycytidine 5'-triphosphate] CTD PMID:28823149, PMID:31286773 NCBI chr 2:27,305,718...27,364,906
Ensembl chr 2:27,305,728...27,364,906
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19787
    role 19734
      biological role 19734
        biochemical role 19282
          metabolite 19263
            prokaryotic metabolite 18357
              bacterial metabolite 18357
                Escherichia coli metabolite 18262
                  dCTP 2
                    5-iododeoxycytidine triphosphate 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19787
    subatomic particle 19784
      composite particle 19784
        hadron 19784
          baryon 19784
            nucleon 19784
              atomic nucleus 19784
                atom 19784
                  main group element atom 19672
                    p-block element atom 19672
                      chalcogen 19362
                        oxygen atom 19323
                          oxygen molecular entity 19323
                            hydroxides 19068
                              oxoacid 18193
                                pnictogen oxoacid 10146
                                  phosphorus oxoacid 9033
                                    phosphoric acids 7795
                                      phosphoric acid 7795
                                        phosphoric acid derivative 7474
                                          phosphate 7474
                                            organic phosphate 7473
                                              carbohydrate phosphate 1529
                                                phospho sugar 1455
                                                  aldose phosphate 1453
                                                    aldopentose phosphate 1447
                                                      deoxyaldopentose phosphate 9
                                                        2-deoxyribose phosphate 9
                                                          2'-deoxyribonucleotide 8
                                                            2'-deoxyribonucleoside 5'-phosphate 8
                                                              2'-deoxyribonucleoside 5'-triphosphate 3
                                                                pyrimidine 2'-deoxyribonucleoside 5'-triphosphate 2
                                                                  dCTP 2
                                                                    5-iododeoxycytidine triphosphate 0
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