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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:dCTP
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Accession:CHEBI:16311 term browser browse the term
Definition:A 2'-deoxycytidine phosphate having cytosine as the nucleobase.
Synonyms:exact_synonym: 2'-deoxycytidine 5'-(tetrahydrogen triphosphate)
 related_synonym: 2'-Deoxycytidine 5'-triphosphate;   2'-deoxy-CTP;   2'-deoxycytidine triphosphate;   Deoxycytidine 5'-triphosphate;   Deoxycytidine triphosphate;   Formula=C9H16N3O13P3;   InChI=1S/C9H16N3O13P3/c10-7-1-2-12(9(14)11-7)8-3-5(13)6(23-8)4-22-27(18,19)25-28(20,21)24-26(15,16)17/h1-2,5-6,8,13H,3-4H2,(H,18,19)(H,20,21)(H2,10,11,14)(H2,15,16,17)/t5-,6+,8+/m0/s1;   InChIKey=RGWHQCVHVJXOKC-SHYZEUOFSA-N;   SMILES=NC1=NC(=O)N(C=C1)[C@H]1C[C@H](O)[C@@H](COP(O)(=O)OP(O)(=O)OP(O)(O)=O)O1;   deoxy-CTP
 alt_id: CHEBI:10494;   CHEBI:14072;   CHEBI:19243;   CHEBI:41805
 xref: CAS:2056-98-6;   Chemspider:58601;   DrugBank:DB03258;   FooDB:FDB022359;   HMDB:HMDB0000998;   KEGG:C00458
 xref_mesh: MESH:C024107
 xref: PDBeChem:DCP;   PMID:11200258;   PMID:15787173;   PMID:15935150;   PMID:16061253;   PMID:16061997;   PMID:16120835;   PMID:19328748;   PMID:22212996;   PMID:29989586;   PMID:31377845;   PMID:32800127;   PMID:32926292;   PMID:34110794;   PMID:6601514;   PMID:761229;   PMID:7877593;   Wikipedia:Deoxycytidine_triphosphate
 cyclic_relationship: is_conjugate_acid_of CHEBI:57724


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dCTP term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dck deoxycytidine kinase increases metabolic processing
affects activity		 ISO DCK protein results in increased metabolism of 2'-deoxycytidine 5'-triphosphate
2'-deoxycytidine 5'-triphosphate affects the activity of DCK protein		 CTD PMID:9586059 NCBI chr14:19,305,218...19,326,247
Ensembl chr14:19,305,218...19,326,247 		JBrowse link
G Polk DNA polymerase kappa multiple interactions
affects binding		 ISO 2'-deoxycytidine 5'-triphosphate promotes the reaction [N(2)-furfuryl-deoxyguanosine results in increased stability of POLK protein]; N-(2'-deoxyguanosin-8-yl)-3-aminobenzanthrone inhibits the reaction [POLK protein binds to 2'-deoxycytidine 5'-triphosphate] CTD PMID:28823149 PMID:31286773 NCBI chr 2:27,822,228...27,882,331
Ensembl chr 2:27,822,679...27,882,313 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19899
    role 19869
      biological role 19867
        biochemical role 19574
          metabolite 19561
            prokaryotic metabolite 18616
              bacterial metabolite 18616
                Escherichia coli metabolite 18525
                  dCTP 2
                    5-iododeoxycytidine triphosphate 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19899
    subatomic particle 19897
      composite particle 19897
        hadron 19897
          baryon 19897
            nucleon 19897
              atomic nucleus 19897
                atom 19897
                  main group element atom 19835
                    p-block element atom 19835
                      chalcogen 19586
                        oxygen atom 19558
                          oxygen molecular entity 19558
                            hydroxides 19366
                              oxoacid 18804
                                pnictogen oxoacid 14996
                                  phosphorus oxoacid 14594
                                    phosphoric acids 13940
                                      phosphoric acid 13940
                                        phosphoric acid derivative 13850
                                          phosphate 13849
                                            organic phosphate 13849
                                              carbohydrate phosphate 1966
                                                phospho sugar 1811
                                                  aldose phosphate 1808
                                                    aldopentose phosphate 1800
                                                      deoxyaldopentose phosphate 9
                                                        2-deoxyribose phosphate 9
                                                          2'-deoxyribonucleotide 8
                                                            2'-deoxyribonucleoside 5'-phosphate 8
                                                              2'-deoxyribonucleoside 5'-triphosphate 3
                                                                pyrimidine 2'-deoxyribonucleoside 5'-triphosphate 2
                                                                  dCTP 2
                                                                    5-iododeoxycytidine triphosphate 0
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