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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:phytanic acid
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Accession:CHEBI:16285 term browser browse the term
Definition:A branched-chain saturated fatty acid consisting of hexadecanoic acid carrying methyl substituents at positions 3, 7, 11 and 15.
Synonyms:exact_synonym: 3,7,11,15-tetramethylhexadecanoic acid
 related_synonym: 3,7,11,15-Tetramethyl-hexadecansaeure;   3,7,11,15-tetramethyl-hexadecanoic acid;   Formula=C20H40O2;   InChI=1S/C20H40O2/c1-16(2)9-6-10-17(3)11-7-12-18(4)13-8-14-19(5)15-20(21)22/h16-19H,6-15H2,1-5H3,(H,21,22);   InChIKey=RLCKHJSFHOZMDR-UHFFFAOYSA-N;   SMILES=CC(C)CCCC(C)CCCC(C)CCCC(C)CC(O)=O
 alt_id: CHEBI:26111;   CHEBI:8189
 xref: Beilstein:1789963;   CAS:14721-66-5;   KEGG:C01607;   LIPID_MAPS_instance:LMFA01020251
 xref_mesh: MESH:D010831
 xref: PMID:12187408;   PMID:17956237;   PMID:9819701;   Reaxys:1789963
 cyclic_relationship: is_conjugate_acid_of CHEBI:37257


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phytanic acid term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fabp1 fatty acid binding protein 1, liver affects binding
multiple interactions
increases expression
EXP Phytanic Acid binds to FABP1 protein
PPARA protein affects the reaction [Phytanic Acid results in increased expression of FABP1 mRNA]
Phytanic Acid results in increased expression of FABP1 mRNA; Phytanic Acid results in increased expression of FABP1 protein
CTD PMID:10191295 NCBI chr 6:71,199,879...71,205,034
Ensembl chr 6:71,199,827...71,205,023
JBrowse link
G Ppara peroxisome proliferator activated receptor alpha multiple interactions
affects binding
EXP
ISO
PPARA protein affects the reaction [Phytanic Acid results in increased expression of FABP1 mRNA]
Phytanic Acid binds to PPARA protein
CTD PMID:10191295 PMID:23843199 NCBI chr15:85,734,910...85,806,851
Ensembl chr15:85,734,983...85,802,819
JBrowse link
G Ppard peroxisome proliferator activator receptor delta affects binding ISO Phytanic Acid binds to PPARB protein CTD PMID:23843199 NCBI chr17:28,232,754...28,301,469
Ensembl chr17:28,232,700...28,301,474
JBrowse link
G Pparg peroxisome proliferator activated receptor gamma affects binding ISO Phytanic Acid binds to PPARG protein CTD PMID:23843199 NCBI chr 6:115,360,879...115,490,404
Ensembl chr 6:115,360,951...115,490,399
JBrowse link
G Rxrb retinoid X receptor beta affects binding ISO Phytanic Acid binds to RXRB protein CTD PMID:11939783 NCBI chr17:34,031,812...34,038,403
Ensembl chr17:34,031,812...34,038,399
JBrowse link
G Scp2 sterol carrier protein 2, liver affects degradation EXP SCP2 protein affects the degradation of Phytanic Acid CTD PMID:10191295 NCBI chr 4:108,043,830...108,144,971
Ensembl chr 4:108,043,839...108,144,998
JBrowse link
2-hydroxyphytanic acid term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Rxra retinoid X receptor alpha affects binding ISO 2-hydroxyphytanic acid binds to RXRA protein CTD PMID:23843199 NCBI chr 2:27,676,445...27,763,319
Ensembl chr 2:27,676,440...27,762,957
JBrowse link
G Rxrb retinoid X receptor beta affects binding ISO 2-hydroxyphytanic acid binds to RXRB protein CTD PMID:23843199 NCBI chr17:34,031,812...34,038,403
Ensembl chr17:34,031,812...34,038,399
JBrowse link
G Rxrg retinoid X receptor gamma affects binding ISO 2-hydroxyphytanic acid binds to RXRG protein CTD PMID:23843199 NCBI chr 1:167,598,362...167,639,623
Ensembl chr 1:167,598,384...167,639,623
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 21549
    role 21527
      biological role 21525
        biochemical role 20689
          metabolite 20639
            eukaryotic metabolite 20487
              plant metabolite 18531
                hexadecanoic acid 535
                  phytanic acid 8
                    2-hydroxyphytanic acid + 3
                    2-oxophytanic acid 0
                    omega-hydroxyphytanic acid 0
                    phytanoyl-CoA + 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 21549
    subatomic particle 21534
      composite particle 21534
        hadron 21534
          baryon 21534
            nucleon 21534
              atomic nucleus 21534
                atom 21534
                  main group element atom 21437
                    p-block element atom 21437
                      carbon group element atom 21227
                        carbon atom 21124
                          organic molecular entity 21124
                            organic group 19557
                              organic divalent group 19547
                                organodiyl group 19547
                                  carbonyl group 19528
                                    carbonyl compound 19528
                                      carboxylic acid 19116
                                        monocarboxylic acid 18392
                                          fatty acid 16584
                                            saturated fatty acid 16560
                                              straight-chain saturated fatty acid 15902
                                                hexadecanoic acid 535
                                                  phytanic acid 8
                                                    2-hydroxyphytanic acid + 3
                                                    2-oxophytanic acid 0
                                                    omega-hydroxyphytanic acid 0
                                                    phytanoyl-CoA + 0
paths to the root