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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:N,N-dimethylaniline
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Accession:CHEBI:16269 term browser browse the term
Definition:A tertiary amine that is aniline in which the amino hydrogens are replaced by two methyl groups.
Synonyms:related_synonym: Dimethylaminobenzene;   Dimethylaniline;   Dimethylphenylamine;   Formula=C8H11N;   InChI=1S/C8H11N/c1-9(2)8-6-4-3-5-7-8/h3-7H,1-2H3;   InChIKey=JLTDJTHDQAWBAV-UHFFFAOYSA-N;   N,N-Dimethyl-N-phenylamine;   N,N-Dimethylbenzenamine;   N,N-Dimethylbenzeneamine;   N,N-Dimethylphenylamine;   SMILES=CN(C)c1ccccc1
 alt_id: CHEBI:12423;   CHEBI:21452;   CHEBI:7074
 xref: CAS:121-69-7;   HMDB:HMDB0001020;   KEGG:C02846
 xref_mesh: MESH:C015157
 xref: MetaCyc:NN-DIMETHYLANILINE;   PMID:24315030;   Reaxys:507140;   Wikipedia:Dimethylaniline


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N,N-dimethylaniline term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Axin2 axin 2 decreases expression ISO N,N-dimethylaniline analog results in decreased expression of AXIN2 protein CTD PMID:21291235 NCBI chr10:93,893,830...93,927,042
Ensembl chr10:93,899,245...93,926,231 		JBrowse link
G Cyp2a1 cytochrome P450, family 2, subfamily a, polypeptide 1 increases metabolic processing
multiple interactions		 ISO CYP2A13 protein results in increased metabolism of N,N-dimethylaniline
CYP2A13 gene polymorphism inhibits the reaction [CYP2A13 protein results in increased metabolism of N,N-dimethylaniline]		 CTD PMID:18669584 NCBI chr 1:82,231,611...82,244,887
Ensembl chr 1:82,231,611...82,244,887 		JBrowse link
G Myc MYC proto-oncogene, bHLH transcription factor decreases expression ISO N,N-dimethylaniline analog results in decreased expression of MYC protein CTD PMID:21291235 NCBI chr 7:93,593,705...93,598,633
Ensembl chr 7:93,593,705...93,598,630 		JBrowse link
G Pygo2 pygopus family PHD finger 2 decreases expression ISO N,N-dimethylaniline analog results in decreased expression of PYGO2 protein CTD PMID:21291235 NCBI chr 2:174,849,670...174,854,758
Ensembl chr 2:174,849,936...174,854,758 		JBrowse link
G Tcf7l2 transcription factor 7 like 2 decreases expression ISO N,N-dimethylaniline analog results in decreased expression of TCF7L2 mRNA; N,N-dimethylaniline analog results in decreased expression of TCF7L2 protein CTD PMID:21291235 NCBI chr 1:254,785,956...254,978,967
Ensembl chr 1:254,786,091...254,978,967 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 20089
    role 20042
      application 19781
        refrigerant 18091
          ammonia 17521
            organic amino compound 17521
              amine 7919
                tertiary amine 627
                  N,N-dimethylaniline 5
                    N,N-dimethylaniline N-oxide 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 20089
    subatomic particle 20058
      composite particle 20058
        hadron 20088
          baryon 20088
            nucleon 20088
              atomic nucleus 20088
                atom 20058
                  main group element atom 19960
                    main group molecular entity 19960
                      s-block molecular entity 19784
                        hydrogen molecular entity 19777
                          hydrides 19115
                            inorganic hydride 17901
                              pnictogen hydride 17884
                                nitrogen hydride 17773
                                  azane 17503
                                    ammonia 17521
                                      organic amino compound 17521
                                        aromatic amine 14915
                                          anilines 13987
                                            substituted aniline 13665
                                              methylaniline 10
                                                dimethylaniline 10
                                                  N,N-dimethylaniline 5
                                                    N,N-dimethylaniline N-oxide 0
paths to the root