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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:succinic semialdehyde
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Accession:CHEBI:16265 term browser browse the term
Definition:An aldehydic acid that has formula C4H6O3.
Synonyms:exact_synonym: 4-oxobutanoic acid
 related_synonym: 3-formylpropanoic acid;   3-formylpropionic acid;   4-Oxobutanoate;   Formula=C4H6O3;   InChI=1S/C4H6O3/c5-3-1-2-4(6)7/h3H,1-2H2,(H,6,7);   InChIKey=UIUJIQZEACWQSV-UHFFFAOYSA-N;   SMILES=[H]C(=O)CCC(O)=O;   Succinate semialdehyde;   beta-formylpropionic acid;   semialdehyde succinique;   succinaldehydic acid;   succinic acid semialdehyde
 alt_id: CHEBI:15126;   CHEBI:26804;   CHEBI:9305
 xref: Beilstein:1745187;   CAS:692-29-5;   KEGG:C00232;   KNApSAcK:C00019682
 xref_mesh: MESH:C009338
 xref: UM-BBD_compID:c0311
 cyclic_relationship: is_conjugate_acid_of CHEBI:57706



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succinic semialdehyde term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Akr1a1 aldo-keto reductase family 1 member A1 increases reduction ISO AKR1A1 protein results in increased reduction of succinic semialdehyde CTD PMID:10510318 PMID:21276435 NCBI chr 5:130,092,945...130,130,277
Ensembl chr 5:130,092,732...130,113,674
JBrowse link
G Akr7a2 aldo-keto reductase family 7, member A2 increases reduction
affects reduction
ISO AKR7A2 protein results in increased reduction of succinic semialdehyde
succinic semialdehyde affects the reduction of AKR7A5 protein
CTD PMID:10510318 PMID:12604212 NCBI chr 5:151,552,375...151,560,914
Ensembl chr 5:151,552,343...151,560,909
JBrowse link
G Akr7a3 aldo-keto reductase family 7 member A3 affects metabolic processing EXP AKR7A3 protein affects the metabolism of succinic semialdehyde CTD PMID:15019089 NCBI chr 5:151,590,968...151,601,394
Ensembl chr 5:151,584,479...151,601,394
JBrowse link
G Aldh5a1 aldehyde dehydrogenase 5 family, member A1 increases metabolic processing EXP ALDH5A1 protein results in increased metabolism of succinic semialdehyde CTD PMID:17010440 PMID:18926807 NCBI chr17:40,132,339...40,158,677
Ensembl chr17:40,130,883...40,158,677
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 20056
    role 20008
      application 19745
        solvent 16663
          formic acid 8827
            formyl group 8800
              aldehyde 8800
                aldehydic acid 15
                  succinic semialdehyde 4
                    ethyl 4-oxobutanoate 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 20056
    subatomic particle 20054
      composite particle 20054
        hadron 20054
          baryon 20054
            nucleon 20054
              atomic nucleus 20054
                atom 20054
                  main group element atom 19956
                    p-block element atom 19956
                      carbon group element atom 19882
                        carbon atom 19875
                          organic molecular entity 19875
                            organic group 18961
                              organic divalent group 18947
                                organodiyl group 18947
                                  carbonyl group 18900
                                    carbonyl compound 18900
                                      carboxylic acid 18594
                                        carboacyl group 17706
                                          univalent carboacyl group 17706
                                            formyl group 8800
                                              aldehyde 8800
                                                aldehydic acid 15
                                                  succinic semialdehyde 4
                                                    ethyl 4-oxobutanoate 0
paths to the root