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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:UDP-N-acetyl-alpha-D-glucosamine
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Accession:CHEBI:16264 term browser browse the term
Definition:A UDP-amino sugar having N-acetyl-alpha-D-glucosamine as the amino sugar component.
Synonyms:exact_synonym: uridine 5'-[3-(2-acetamido-2-deoxy-alpha-D-glucopyranosyl) dihydrogen diphosphate]
 related_synonym: (2R,3R,4R,5S,6R)-3-(acetylamino)-4,5-dihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl [(2R,3S,4R,5R)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-3,4-dihydroxytetrahydrofuran-2-yl]methyl dihydrogen diphosphate (non-preferred name);   Formula=C17H27N3O17P2;   InChI=1S/C17H27N3O17P2/c1-6(22)18-10-13(26)11(24)7(4-21)35-16(10)36-39(31,32)37-38(29,30)33-5-8-12(25)14(27)15(34-8)20-3-2-9(23)19-17(20)28/h2-3,7-8,10-16,21,24-27H,4-5H2,1H3,(H,18,22)(H,29,30)(H,31,32)(H,19,23,28)/t7-,8-,10-,11-,12-,13-,14-,15-,16-/m1/s1;   InChIKey=LFTYTUAZOPRMMI-CFRASDGPSA-N;   SMILES=CC(=O)N[C@@H]1[C@@H](O)[C@H](O)[C@@H](CO)O[C@@H]1OP(O)(=O)OP(O)(=O)OC[C@H]1O[C@H]([C@H](O)[C@@H]1O)n1ccc(=O)[nH]c1=O;   UDP-GlcNAc;   UDP-N-acetyl-D-glucosamine;   UDP-N-acetylglucosamine;   URIDINE-DIPHOSPHATE-N-ACETYLGLUCOSAMINE
 alt_id: CHEBI:13456;   CHEBI:13473;   CHEBI:13475;   CHEBI:13476;   CHEBI:22115;   CHEBI:46243;   CHEBI:9823
 xref: CAS:528-04-1;   HMDB:HMDB0000290;   KEGG:C00043;   KEGG:G10610;   KNApSAcK:C00019358
 xref_mesh: MESH:D014537
 xref: PDBeChem:UD1;   PMID:21627825;   PMID:22825354;   PMID:22887999;   PMID:22901411;   Reaxys:78982
 cyclic_relationship: is_conjugate_acid_of CHEBI:57705



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UDP-N-acetyl-alpha-D-glucosamine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Idh2 isocitrate dehydrogenase (NADP(+)) 2 multiple interactions
increases abundance
ISO Triazines inhibits the reaction [IDH2 protein mutant form results in increased abundance of Uridine Diphosphate N-Acetylglucosamine] CTD PMID:27469509 NCBI chr 1:134,038,644...134,057,969
Ensembl chr 1:134,029,772...134,058,025
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  CHEBI ontology 19800
    role 19751
      biological role 19751
        biochemical role 19368
          metabolite 19344
            prokaryotic metabolite 18410
              bacterial metabolite 18410
                Escherichia coli metabolite 18301
                  UDP-N-acetyl-alpha-D-glucosamine 1
Path 2
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  CHEBI ontology 19800
    subatomic particle 19799
      composite particle 19799
        hadron 19799
          baryon 19799
            nucleon 19799
              atomic nucleus 19799
                atom 19799
                  main group element atom 19698
                    p-block element atom 19698
                      chalcogen 19450
                        oxygen atom 19423
                          oxygen molecular entity 19423
                            hydroxides 19158
                              oxoacid 18472
                                pnictogen oxoacid 10733
                                  phosphorus oxoacid 9728
                                    phosphoric acids 8536
                                      phosphoric acid 8536
                                        phosphoric acid derivative 8242
                                          phosphate 8242
                                            organic phosphate 8241
                                              carbohydrate phosphate 1738
                                                phospho sugar 1663
                                                  aldose phosphate 1661
                                                    aldopentose phosphate 1653
                                                      ribose phosphate 1648
                                                        ribonucleotide 1611
                                                          ribonucleoside 5'-phosphate 611
                                                            ribonucleoside 5'-diphosphate 111
                                                              pyrimidine ribonucleoside 5'-diphosphate 21
                                                                UDP 16
                                                                  UDP-sugar 8
                                                                    UDP-amino sugar 2
                                                                      UDP-alpha-D-glucosamine 1
                                                                        UDP-D-glucosamine 1
                                                                          UDP-N-acetyl-alpha-D-glucosamine 1
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