Send us a Message



 Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap)  (beta) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer) Overgo Probe Designer
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease COVID-19 Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models   new Genetic Models Autism Models PhenoMiner (Quantitative Phenotypes) Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes GERRC (Gene Editing Rat Resource Center) Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Poster Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources

CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:cholest-4-en-3-one
go back to main search page
Accession:CHEBI:16175 term browser browse the term
Definition:A cholestanoid that is cholest-4-ene substituted by an oxo group at position 3.
Synonyms:related_synonym: 4-cholesten-3-one;   Cholestenone;   Formula=C27H44O;   InChI=1S/C27H44O/c1-18(2)7-6-8-19(3)23-11-12-24-22-10-9-20-17-21(28)13-15-26(20,4)25(22)14-16-27(23,24)5/h17-19,22-25H,6-16H2,1-5H3/t19-,22+,23-,24+,25+,26+,27-/m1/s1;   InChIKey=NYOXRYYXRWJDKP-GYKMGIIDSA-N;   SMILES=[H][C@@]1(CC[C@@]2([H])[C@]3([H])CCC4=CC(=O)CC[C@]4(C)[C@@]3([H])CC[C@]12C)[C@H](C)CCCC(C)C
 alt_id: CHEBI:13979;   CHEBI:23171;   CHEBI:3657;   CHEBI:86563
 xref: CAS:601-57-0;   FooDB:FDB022319;   HMDB:HMDB0000921;   KEGG:C00599;   KNApSAcK:C00036093;   LIPID_MAPS_instance:LMST01010015
 xref_mesh: MESH:C000475
 xref: MetaCyc:CPD-323;   PDBeChem:K2B;   PMID:10566877;   PMID:11958788;   PMID:12036855;   PMID:12777473;   PMID:12943786;   PMID:14597406;   PMID:17496168;   PMID:20671299;   PMID:24465993;   PMID:24565079;   PMID:24927729;   PMID:29201491;   PMID:29413944;   PMID:29573289;   PMID:31477154;   PMID:6892636


show annotations for term's descendants           Sort by:
cholest-4-en-3-one term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Akr1d1 aldo-keto reductase family 1, member D1 multiple interactions ISO [AKR1D1 protein co-treated with NADP] results in increased reduction of cholest-4-en-3-one CTD PMID:25500266 NCBI chr 4:66,154,246...66,187,505
Ensembl chr 4:66,154,248...66,186,372 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19765
    chemical entity 19763
      group 19727
        organic group 18856
          3-oxo-Delta(4)-steroid group 9149
            3-oxo-Delta(4) steroid 9149
              cholest-4-en-3-one 1
                25-hydroxycholest-4-en-3-one 0
                26-hydroxycholest-4-en-3-one + 0
                3-ketocholest-4-en-26-al + 0
                7alpha,25-dihydroxy-4-cholesten-3-one 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19765
    subatomic particle 19763
      composite particle 19763
        hadron 19763
          baryon 19763
            nucleon 19763
              atomic nucleus 19763
                atom 19763
                  main group element atom 19712
                    p-block element atom 19712
                      carbon group element atom 19658
                        carbon atom 19654
                          organic molecular entity 19654
                            organic group 18856
                              organic divalent group 18842
                                organodiyl group 18842
                                  carbonyl group 18807
                                    carbonyl compound 18807
                                      ketone 17109
                                        oxo steroid 10313
                                          3-oxo steroid 9915
                                            3-oxo-Delta(4) steroid 9149
                                              cholest-4-en-3-one 1
                                                25-hydroxycholest-4-en-3-one 0
                                                26-hydroxycholest-4-en-3-one + 0
                                                3-ketocholest-4-en-26-al + 0
                                                7alpha,25-dihydroxy-4-cholesten-3-one 0
paths to the root