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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:cholest-4-en-3-one
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Accession:CHEBI:16175 term browser browse the term
Definition:A cholestanoid that is cholest-4-ene substituted by an oxo group at position 3.
Synonyms:related_synonym: 4-cholesten-3-one;   Cholestenone;   Formula=C27H44O;   InChI=1S/C27H44O/c1-18(2)7-6-8-19(3)23-11-12-24-22-10-9-20-17-21(28)13-15-26(20,4)25(22)14-16-27(23,24)5/h17-19,22-25H,6-16H2,1-5H3/t19-,22+,23-,24+,25+,26+,27-/m1/s1;   InChIKey=NYOXRYYXRWJDKP-GYKMGIIDSA-N;   SMILES=[H][C@@]1(CC[C@@]2([H])[C@]3([H])CCC4=CC(=O)CC[C@]4(C)[C@@]3([H])CC[C@]12C)[C@H](C)CCCC(C)C
 alt_id: CHEBI:13979;   CHEBI:23171;   CHEBI:3657;   CHEBI:86563
 xref: CAS:601-57-0;   FooDB:FDB022319;   HMDB:HMDB0000921;   KEGG:C00599;   KNApSAcK:C00036093;   LIPID_MAPS_instance:LMST01010015
 xref_mesh: MESH:C000475
 xref: MetaCyc:CPD-323;   PDBeChem:K2B;   PMID:10566877;   PMID:11958788;   PMID:12036855;   PMID:12777473;   PMID:12943786;   PMID:14597406;   PMID:17496168;   PMID:20671299;   PMID:24465993;   PMID:24565079;   PMID:24927729;   PMID:29201491;   PMID:29413944;   PMID:29573289;   PMID:31477154;   PMID:6892636


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cholest-4-en-3-one term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Akr1d1 aldo-keto reductase family 1, member D1 multiple interactions ISO [AKR1D1 protein co-treated with NADP] results in increased reduction of cholest-4-en-3-one CTD PMID:25500266 NCBI chr 4:65,110,706...65,143,930
Ensembl chr 4:65,110,746...65,143,941
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Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19792
    chemical entity 19791
      group 19698
        organic group 18508
          3-oxo-Delta(4)-steroid group 7939
            3-oxo-Delta(4) steroid 7939
              cholest-4-en-3-one 1
                25-hydroxycholest-4-en-3-one 0
                26-hydroxycholest-4-en-3-one + 0
                3-ketocholest-4-en-26-al + 0
                7alpha,25-dihydroxy-4-cholesten-3-one 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19792
    subatomic particle 19788
      composite particle 19788
        hadron 19788
          baryon 19788
            nucleon 19788
              atomic nucleus 19788
                atom 19788
                  main group element atom 19675
                    p-block element atom 19675
                      carbon group element atom 19571
                        carbon atom 19560
                          organic molecular entity 19560
                            organic group 18508
                              organic divalent group 18501
                                organodiyl group 18501
                                  carbonyl group 18404
                                    carbonyl compound 18404
                                      ketone 16152
                                        oxo steroid 9281
                                          3-oxo steroid 8810
                                            3-oxo-Delta(4) steroid 7939
                                              cholest-4-en-3-one 1
                                                25-hydroxycholest-4-en-3-one 0
                                                26-hydroxycholest-4-en-3-one + 0
                                                3-ketocholest-4-en-26-al + 0
                                                7alpha,25-dihydroxy-4-cholesten-3-one 0
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