|
G |
A1bg |
alpha-1-B glycoprotein |
affects expression |
ISO |
Mercury affects the expression of A1BG protein |
CTD |
PMID:22030286 |
|
NCBI chr 7:92,493,934...92,498,460
|
|
G |
A2m |
alpha-2-macroglobulin |
decreases expression |
ISO |
Mercury results in decreased expression of A2M mRNA |
CTD |
PMID:17547211 |
|
NCBI chr 4:154,897,770...154,947,787
|
|
G |
Abca1 |
ATP binding cassette subfamily A member 1 |
affects expression |
ISO |
Mercury affects the expression of ABCA1 mRNA |
CTD |
PMID:23920476 |
|
NCBI chr 5:72,473,676...72,596,563
|
|
G |
Abcb1a |
ATP binding cassette subfamily B member 1A |
multiple interactions |
ISO |
[ABCB1 gene SNP affects the susceptibility to Mercury] which affects the abundance of Mercury; ABCB1 gene SNP affects the susceptibility to and affects the abundance of Mercury |
CTD |
PMID:27262785 PMID:32946573 |
|
NCBI chr 4:26,312,403...26,488,456
|
|
G |
Abcb1b |
ATP-binding cassette, sub-family B member 1B |
increases expression |
EXP |
Mercury results in increased expression of ABCB1B mRNA |
CTD |
PMID:12730625 |
|
NCBI chr 4:26,197,706...26,280,156
|
|
G |
Abcc1 |
ATP binding cassette subfamily C member 1 |
increases expression multiple interactions |
EXP ISO |
Mercury results in increased expression of ABCC1 mRNA; Mercury results in increased expression of ABCC1 protein ABCC1 gene SNP affects the susceptibility to and affects the abundance of Mercury |
CTD |
PMID:12730625 PMID:27262785 |
|
NCBI chr10:1,022,041...1,162,431
|
|
G |
Abcc2 |
ATP binding cassette subfamily C member 2 |
multiple interactions affects response to substance increases export increases transport affects transport |
ISO EXP |
ABCC2 gene SNP affects the susceptibility to and affects the abundance of Mercury; ABCC2 protein affects the transport of [Mercury co-treated with Cysteine]; Adenosine Triphosphate affects the reaction [ABCC2 protein results in increased transport of Mercury] ABCC2 gene mutant form affects the susceptibility to Mercury ABCC2 protein results in increased export of Mercury ABCC2 protein affects the transport of Mercury EPO protein promotes the reaction [Mercury results in increased expression of and affects the localization of ABCC2 protein]; Mercury results in increased expression of and affects the localization of ABCC2 protein |
CTD |
PMID:21134393 PMID:23052037 PMID:23059061 PMID:24039982 PMID:25145654 PMID:27262785 PMID:32909846 More...
|
|
NCBI chr 1:252,613,875...252,672,459
|
|
G |
Abcg1 |
ATP binding cassette subfamily G member 1 |
increases expression |
ISO |
Mercury results in increased expression of ABCG1 mRNA |
CTD |
PMID:16823088 |
|
NCBI chr20:9,128,056...9,184,312
|
|
G |
Abcg2 |
ATP binding cassette subfamily G member 2 |
increases expression |
ISO |
Mercury results in increased expression of ABCG2 mRNA |
CTD |
PMID:17547211 |
|
NCBI chr 4:89,006,056...89,132,915
|
|
G |
Abl1 |
ABL proto-oncogene 1, non-receptor tyrosine kinase |
increases expression |
ISO |
Mercury results in increased expression of ABL1 mRNA |
CTD |
PMID:19937285 |
|
NCBI chr 3:35,377,587...35,480,843
|
|
G |
Ache |
acetylcholinesterase |
increases activity multiple interactions |
ISO EXP |
Mercury results in increased activity of ACHE protein [Aluminum co-treated with Lead co-treated with Mercury co-treated with Manganese co-treated with Selenium co-treated with Zinc] results in increased activity of ACHE protein; [Aluminum co-treated with Lead co-treated with Mercury co-treated with Manganese co-treated with Selenium] results in increased activity of ACHE protein; [Aluminum co-treated with Lead co-treated with Mercury co-treated with Manganese] results in increased activity of ACHE protein |
CTD |
PMID:10798623 PMID:37415728 |
|
NCBI chr12:25,042,882...25,050,608
|
|
G |
Acp2 |
acid phosphatase 2, lysosomal |
decreases expression |
ISO |
Mercury results in decreased expression of ACP2 mRNA |
CTD |
PMID:17547211 |
|
NCBI chr 3:77,175,022...77,185,180
|
|
G |
Acsl1 |
acyl-CoA synthetase long-chain family member 1 |
decreases expression |
ISO |
Mercury results in decreased expression of ACSL1 mRNA |
CTD |
PMID:17547211 |
|
NCBI chr16:45,755,246...45,821,541
|
|
G |
Actb |
actin, beta |
increases expression |
EXP |
Mercury results in increased expression of ACTB mRNA |
CTD |
PMID:22688007 |
|
NCBI chr12:16,776,664...16,779,634
|
|
G |
Adck5 |
aarF domain containing kinase 5 |
decreases expression |
ISO |
Mercury analog results in decreased expression of ADCK5 mRNA |
CTD |
PMID:25056781 |
|
NCBI chr 7:108,301,623...108,319,439
|
|
G |
Adm |
adrenomedullin |
increases expression |
ISO |
Mercury results in increased expression of ADM mRNA |
CTD |
PMID:17547211 |
|
NCBI chr 1:174,164,178...174,182,372
|
|
G |
Ahr |
aryl hydrocarbon receptor |
multiple interactions |
ISO |
Mercury results in increased activity of [AHR protein binds to ARNT protein] |
CTD |
PMID:16093525 |
|
NCBI chr 6:57,961,423...57,998,901
|
|
G |
Akr1b1 |
aldo-keto reductase family 1 member B1 |
decreases expression |
ISO |
Mercury results in decreased expression of AKR1B1 mRNA |
CTD |
PMID:17547211 |
|
NCBI chr 4:63,899,222...63,913,315
|
|
G |
Akr7a3 |
aldo-keto reductase family 7 member A3 |
multiple interactions |
EXP |
[Mercuric Chloride results in increased abundance of Mercury] which results in increased expression of AKR7A3 mRNA; [Mercuric Chloride results in increased abundance of Mercury] which results in increased expression of AKR7A3 protein |
CTD |
PMID:29298499 |
|
NCBI chr 5:151,590,968...151,601,394
|
|
G |
Akt1s1 |
AKT1 substrate 1 |
decreases expression |
ISO |
Mercury results in decreased expression of AKT1S1 mRNA |
CTD |
PMID:22008530 |
|
NCBI chr 1:104,469,823...104,476,168
|
|
G |
Akt2 |
AKT serine/threonine kinase 2 |
decreases expression |
ISO |
Mercury results in decreased expression of AKT2 mRNA |
CTD |
PMID:16823088 |
|
NCBI chr 1:92,004,705...92,061,420
|
|
G |
Alad |
aminolevulinate dehydratase |
multiple interactions decreases activity affects abundance |
ISO |
[zinc chloride inhibits the reaction [Mercuric Chloride results in decreased activity of ALAD protein]] which affects the abundance of Mercury; Sodium Selenite inhibits the reaction [Mercury results in decreased activity of ALAD protein] ALAD gene polymorphism affects the abundance of Mercury |
CTD |
PMID:12499120 PMID:14615064 PMID:25728017 |
|
NCBI chr 5:75,961,993...75,972,334
|
|
G |
Alb |
albumin |
increases export multiple interactions |
ISO EXP |
Mercury results in increased export of ALB protein [Lead co-treated with Cadmium co-treated with Mercury co-treated with Arsenic] results in decreased expression of ALB protein; [Selenium co-treated with Zinc] inhibits the reaction [[Lead co-treated with Cadmium co-treated with Mercury co-treated with Arsenic] results in decreased expression of ALB protein]; [Zinc co-treated with Copper co-treated with Manganese co-treated with Potassium Dichromate co-treated with Nickel co-treated with Cadmium co-treated with Lead co-treated with Mercury] affects the expression of ALB protein; Selenium inhibits the reaction [[Lead co-treated with Cadmium co-treated with Mercury co-treated with Arsenic] results in decreased expression of ALB protein]; Zinc inhibits the reaction [[Lead co-treated with Cadmium co-treated with Mercury co-treated with Arsenic] results in decreased expression of ALB protein] |
CTD |
PMID:30090589 PMID:37137463 PMID:37676925 |
|
NCBI chr14:17,891,564...17,907,043
|
|
G |
Aldh5a1 |
aldehyde dehydrogenase 5 family, member A1 |
decreases expression |
ISO |
Mercury analog results in decreased expression of ALDH5A1 mRNA |
CTD |
PMID:25056781 |
|
NCBI chr17:40,132,339...40,158,677
|
|
G |
Aldh6a1 |
aldehyde dehydrogenase 6 family, member A1 |
decreases expression |
ISO |
Mercury results in decreased expression of ALDH6A1 mRNA |
CTD |
PMID:17547211 |
|
NCBI chr 6:104,077,975...104,098,636
|
|
G |
Alg3 |
ALG3, alpha-1,3- mannosyltransferase |
increases expression |
ISO |
Mercury results in increased expression of ALG3 mRNA |
CTD |
PMID:16823088 |
|
NCBI chr11:80,300,487...80,306,014
|
|
G |
Als2 |
alsin Rho guanine nucleotide exchange factor ALS2 |
increases expression |
ISO |
Mercury results in increased expression of ALS2 mRNA |
CTD |
PMID:19937285 |
|
NCBI chr 9:68,107,310...68,180,192
|
|
G |
Ank1 |
ankyrin 1 |
decreases expression |
ISO |
Mercury results in decreased expression of ANK1 mRNA |
CTD |
PMID:19937285 |
|
NCBI chr16:68,876,294...69,054,963
|
|
G |
Ankhd1 |
ankyrin repeat and KH domain containing 1 |
increases expression |
ISO |
Mercury results in increased expression of ANKHD1 mRNA |
CTD |
PMID:16823088 |
|
NCBI chr18:28,436,296...28,534,954
|
|
G |
Anxa2 |
annexin A2 |
increases expression |
ISO |
Mercury results in increased expression of ANXA2 mRNA |
CTD |
PMID:17547211 |
|
NCBI chr 8:78,986,252...79,022,638
|
|
G |
Ap2a2 |
adaptor related protein complex 2 subunit alpha 2 |
decreases expression |
ISO |
Mercury results in decreased expression of AP2A2 mRNA |
CTD |
PMID:19937285 |
|
NCBI chr 1:196,652,315...196,725,609
|
|
G |
Apoa2 |
apolipoprotein A2 |
affects expression |
ISO |
Mercury affects the expression of APOA2 protein |
CTD |
PMID:22030286 |
|
NCBI chr13:83,644,460...83,646,358
|
|
G |
Apoe |
apolipoprotein E |
affects response to substance |
ISO |
APOE gene polymorphism affects the susceptibility to Mercury; APOE polymorphism affects the susceptibility to Mercury |
CTD |
PMID:12897404 PMID:23603214 |
|
NCBI chr 1:88,481,889...88,485,816
|
|
G |
App |
amyloid beta precursor protein |
multiple interactions increases secretion |
ISO |
Estradiol inhibits the reaction [Mercury results in increased secretion of APP protein modified form] Mercury results in increased secretion of APP protein alternative form; Mercury results in increased secretion of APP protein modified form |
CTD |
PMID:12182891 PMID:25673500 |
|
NCBI chr11:37,506,207...37,724,351
|
|
G |
Aqp1 |
aquaporin 1 |
multiple interactions decreases activity |
EXP ISO |
Mercury inhibits the reaction [AQP1 protein results in increased transport of Water] Mercaptoethanol inhibits the reaction [Mercury results in decreased activity of AQP1 protein] |
CTD |
PMID:21259319 PMID:24028651 |
|
NCBI chr 4:85,812,784...85,824,964
|
|
G |
Aqp10 |
aquaporin 10 |
decreases activity affects activity |
ISO |
Mercury results in decreased activity of AQP10 protein Mercury affects the activity of AQP10 protein |
CTD |
PMID:11573934 PMID:12084581 |
|
NCBI chr 2:177,699,717...177,704,620
|
|
G |
Aqp8 |
aquaporin 8 |
multiple interactions |
EXP |
Mercury affects the reaction [AQP8 protein affects the transport of Water] |
CTD |
PMID:18059526 |
|
NCBI chr 1:177,993,313...177,999,158
|
|
G |
Aqp9 |
aquaporin 9 |
multiple interactions |
EXP |
Mercury inhibits the reaction [AQP9 protein results in increased transport of Water] |
CTD |
PMID:21259319 |
|
NCBI chr 8:80,678,027...80,718,273
|
|
G |
Arf4 |
ARF GTPase 4 |
decreases expression |
ISO |
Mercury results in decreased expression of ARF4 mRNA |
CTD |
PMID:16823088 |
|
NCBI chr16:1,896,692...1,913,267
|
|
G |
Arg1 |
arginase 1 |
decreases activity |
EXP |
Mercury results in decreased activity of ARG1 protein |
CTD |
PMID:11916150 |
|
NCBI chr 1:22,295,093...22,307,720
|
|
G |
Arg2 |
arginase 2 |
decreases activity |
EXP |
Mercury results in decreased activity of ARG2 protein |
CTD |
PMID:11916150 |
|
NCBI chr 6:103,669,001...103,694,375
|
|
G |
Arhgef28 |
Rho guanine nucleotide exchange factor 28 |
decreases expression |
ISO |
Mercury results in decreased expression of ARHGEF28 mRNA |
CTD |
PMID:19937285 |
|
NCBI chr 2:29,263,888...29,560,595
|
|
G |
Arid1a |
AT-rich interaction domain 1A |
increases expression |
ISO |
Mercury results in increased expression of ARID1A mRNA |
CTD |
PMID:19937285 |
|
NCBI chr 5:151,192,014...151,269,291
|
|
G |
Arid4a |
AT-rich interaction domain 4A |
affects expression |
ISO |
Mercury affects the expression of ARID4A mRNA |
CTD |
PMID:23920476 |
|
NCBI chr 6:95,258,429...95,335,987
|
|
G |
Arnt |
aryl hydrocarbon receptor nuclear translocator |
multiple interactions |
ISO |
Mercury results in increased activity of [AHR protein binds to ARNT protein] |
CTD |
PMID:16093525 |
|
NCBI chr 2:182,997,731...183,056,584
|
|
G |
Atp1b3 |
ATPase Na+/K+ transporting subunit beta 3 |
increases expression |
EXP |
Mercury results in increased expression of ATP1B3 mRNA |
CTD |
PMID:22688007 |
|
NCBI chr 8:96,910,265...96,941,592
|
|
G |
Atp6v1a |
ATPase H+ transporting V1 subunit A |
decreases expression |
ISO |
Mercury results in decreased expression of ATP6V1A mRNA |
CTD |
PMID:16823088 |
|
NCBI chr11:70,066,800...70,120,603
|
|
G |
Atxn3 |
ataxin 3 |
decreases expression |
ISO |
Mercury analog results in decreased expression of ATXN3 mRNA |
CTD |
PMID:25056781 |
|
NCBI chr 6:126,837,107...126,872,919
|
|
G |
Atxn7l3 |
ataxin 7-like 3 |
decreases expression |
ISO |
Mercury analog results in decreased expression of ATXN7L3 mRNA |
CTD |
PMID:25056781 |
|
NCBI chr10:87,242,843...87,250,186
|
|
G |
Azgp1 |
alpha-2-glycoprotein 1, zinc-binding |
decreases expression |
ISO |
Mercury results in decreased expression of AZGP1 mRNA |
CTD |
PMID:17547211 |
|
NCBI chr12:16,930,990...16,939,333
|
|
G |
B2m |
beta-2 microglobulin |
multiple interactions |
ISO |
[Metals, Heavy results in increased abundance of Mercury] which results in increased secretion of B2M protein |
CTD |
PMID:39357351 |
|
NCBI chr 3:129,549,236...129,555,354
|
|
G |
Bad |
BCL2-associated agonist of cell death |
decreases expression |
ISO |
Mercury results in decreased expression of BAD mRNA |
CTD |
PMID:19937285 |
|
NCBI chr 1:213,562,719...213,572,034
|
|
G |
Bag6 |
BAG cochaperone 6 |
decreases expression |
ISO |
Mercury results in decreased expression of BAG6 mRNA |
CTD |
PMID:16823088 |
|
NCBI chr20:3,675,938...3,690,414
|
|
G |
Bank1 |
B-cell scaffold protein with ankyrin repeats 1 |
increases expression |
ISO |
Mercury results in increased expression of BANK1 mRNA |
CTD |
PMID:16823088 |
|
NCBI chr 2:224,530,475...224,800,420
|
|
G |
Bax |
BCL2 associated X, apoptosis regulator |
increases expression multiple interactions |
EXP ISO |
Mercury results in increased expression of BAX protein [Lead co-treated with Cadmium co-treated with Mercury co-treated with Copper co-treated with Zinc co-treated with Manganese co-treated with Chromium co-treated with Nickel] results in increased expression of BAX protein; Luteolin affects the reaction [[Lead co-treated with Cadmium co-treated with Mercury co-treated with Copper co-treated with Zinc co-treated with Manganese co-treated with Chromium co-treated with Nickel] results in increased expression of BAX protein] |
CTD |
PMID:21186712 PMID:29115570 |
|
NCBI chr 1:105,076,472...105,081,906
|
|
G |
Bcl2 |
BCL2, apoptosis regulator |
decreases expression |
EXP |
Mercury results in decreased expression of BCL2 protein |
CTD |
PMID:21186712 |
|
NCBI chr13:23,204,464...23,366,900
|
|
G |
Bcl2l11 |
Bcl2-like 11 |
decreases expression |
ISO |
Mercury results in decreased expression of BCL2L11 mRNA |
CTD |
PMID:19937285 |
|
NCBI chr 3:135,820,042...135,857,330
|
|
G |
Bcor |
BCL6 co-repressor |
increases expression |
ISO |
Mercury results in increased expression of BCOR mRNA |
CTD |
PMID:16823088 |
|
NCBI chr X:13,282,431...13,402,254
|
|
G |
Bdnf |
brain-derived neurotrophic factor |
decreases expression affects response to substance |
ISO |
Mercury results in decreased expression of BDNF mRNA BDNF polymorphism affects the susceptibility to Mercury |
CTD |
PMID:16301096 PMID:19937285 |
|
NCBI chr 3:116,619,633...116,670,212
|
|
G |
Bhlhe40 |
basic helix-loop-helix family, member e40 |
increases expression |
ISO |
Mercury results in increased expression of BHLHE40 mRNA |
CTD |
PMID:17547211 PMID:19937285 |
|
NCBI chr 4:141,618,453...141,624,154
|
|
G |
Birc3 |
baculoviral IAP repeat-containing 3 |
increases expression |
ISO |
Mercury results in increased expression of BIRC3 mRNA |
CTD |
PMID:16823088 |
|
NCBI chr 8:13,285,702...13,313,329
|
|
G |
Bmpr2 |
bone morphogenetic protein receptor type 2 |
increases expression |
ISO |
Mercury results in increased expression of BMPR2 mRNA |
CTD |
PMID:19937285 |
|
NCBI chr 9:68,685,942...68,801,353
|
|
G |
Braf |
B-Raf proto-oncogene, serine/threonine kinase |
increases expression |
ISO |
Mercury results in increased expression of BRAF mRNA |
CTD |
PMID:19937285 |
|
NCBI chr 4:69,329,772...69,476,931
|
|
G |
Bub1 |
BUB1 mitotic checkpoint serine/threonine kinase |
increases expression |
ISO |
Mercury results in increased expression of BUB1 mRNA |
CTD |
PMID:16823088 |
|
NCBI chr 3:135,473,525...135,504,921
|
|
G |
Bub3 |
BUB3 mitotic checkpoint protein |
decreases expression |
ISO |
Mercury results in decreased expression of BUB3 mRNA |
CTD |
PMID:16823088 |
|
NCBI chr 1:195,760,532...195,771,140
|
|
G |
C3 |
complement C3 |
affects expression |
ISO |
Mercury affects the expression of C3 protein |
CTD |
PMID:22030286 |
|
NCBI chr 9:2,174,412...2,201,339
|
|
G |
C6 |
complement C6 |
affects expression |
ISO |
Mercury affects the expression of C6 protein |
CTD |
PMID:22030286 |
|
NCBI chr 2:53,846,028...53,921,279
|
|
G |
Cadm1 |
cell adhesion molecule 1 |
decreases expression |
ISO |
Mercury results in decreased expression of CADM1 mRNA |
CTD |
PMID:19937285 |
|
NCBI chr 8:47,847,836...48,178,703
|
|
G |
Cadm2 |
cell adhesion molecule 2 |
decreases expression |
ISO |
Mercury analog results in decreased expression of CADM2 mRNA |
CTD |
PMID:25056781 |
|
NCBI chr11:4,548,367...5,525,420
|
|
G |
Calm3 |
calmodulin 3 |
decreases expression |
ISO |
Mercury results in decreased expression of CALM3 mRNA |
CTD |
PMID:16823088 |
|
NCBI chr 1:86,718,761...86,725,869
|
|
G |
Capns1 |
calpain, small subunit 1 |
decreases expression |
ISO |
Mercury analog results in decreased expression of CAPNS1 mRNA |
CTD |
PMID:25056781 |
|
NCBI chr 1:85,444,613...85,454,861
|
|
G |
Capzb |
capping actin protein of muscle Z-line subunit beta |
increases expression |
ISO |
Mercury results in increased expression of CAPZB mRNA |
CTD |
PMID:19937285 |
|
NCBI chr 5:151,435,600...151,535,409
|
|
G |
Car1 |
carbonic anhydrase 1 |
decreases activity |
ISO |
Mercury results in decreased activity of CA1 protein |
CTD |
PMID:18237030 |
|
NCBI chr 2:88,550,681...88,593,454
|
|
G |
Car2 |
carbonic anhydrase 2 |
decreases activity |
ISO |
Mercury results in decreased activity of CA2 protein |
CTD |
PMID:18237030 |
|
NCBI chr 2:88,462,883...88,478,012
|
|
G |
Car3 |
carbonic anhydrase 3 |
increases expression |
ISO |
Mercury results in increased expression of CA3 mRNA |
CTD |
PMID:16823088 |
|
NCBI chr 2:88,491,666...88,501,299
|
|
G |
Carns1 |
carnosine synthase 1 |
decreases expression |
ISO |
Mercury analog results in decreased expression of CARNS1 mRNA |
CTD |
PMID:25056781 |
|
NCBI chr 1:201,459,061...201,470,019
|
|
G |
Casp1 |
caspase 1 |
multiple interactions |
ISO |
CASP1 gene mutant form inhibits the reaction [[Mercuric Chloride results in increased abundance of Mercury] which results in increased expression of IL4 mRNA]; CASP1 gene mutant form inhibits the reaction [[Mercuric Chloride results in increased abundance of Mercury] which results in increased expression of TNF mRNA] |
CTD |
PMID:28453771 |
|
NCBI chr 8:10,746,338...10,882,295
|
|
G |
Casp3 |
caspase 3 |
increases activity increases expression multiple interactions |
ISO EXP |
Mercury results in increased activity of CASP3 protein Mercury results in increased expression of CASP3 protein [Aluminum co-treated with Lead co-treated with Mercury co-treated with Manganese] results in increased expression of CASP3 protein; [Lead co-treated with Cadmium co-treated with Mercury co-treated with Arsenic] results in increased expression of CASP3 protein; [Selenium co-treated with Zinc] inhibits the reaction [[Lead co-treated with Cadmium co-treated with Mercury co-treated with Arsenic] results in increased expression of CASP3 protein]; Selenium inhibits the reaction [[Lead co-treated with Cadmium co-treated with Mercury co-treated with Arsenic] results in increased expression of CASP3 protein]; Zinc inhibits the reaction [[Lead co-treated with Cadmium co-treated with Mercury co-treated with Arsenic] results in increased expression of CASP3 protein] [Lead co-treated with Cadmium co-treated with Mercury co-treated with Copper co-treated with Zinc co-treated with Manganese co-treated with Chromium co-treated with Nickel] results in increased cleavage of CASP3 protein; Luteolin inhibits the reaction [[Lead co-treated with Cadmium co-treated with Mercury co-treated with Copper co-treated with Zinc co-treated with Manganese co-treated with Chromium co-treated with Nickel] results in increased cleavage of CASP3 protein] |
CTD |
PMID:16823075 PMID:21186712 PMID:29115570 PMID:37415728 PMID:37676925 |
|
NCBI chr16:52,395,539...52,413,794
|
|
G |
Casp9 |
caspase 9 |
increases expression multiple interactions |
EXP ISO |
Mercury results in increased expression of CASP9 protein [Lead co-treated with Cadmium co-treated with Mercury co-treated with Copper co-treated with Zinc co-treated with Manganese co-treated with Chromium co-treated with Nickel] results in increased cleavage of CASP9 protein; Luteolin inhibits the reaction [[Lead co-treated with Cadmium co-treated with Mercury co-treated with Copper co-treated with Zinc co-treated with Manganese co-treated with Chromium co-treated with Nickel] results in increased cleavage of CASP9 protein] |
CTD |
PMID:21186712 PMID:29115570 |
|
|
|
G |
Cat |
catalase |
decreases activity multiple interactions |
EXP |
Mercury results in decreased activity of CAT protein [Aluminum co-treated with Lead co-treated with Mercury co-treated with Manganese co-treated with Selenium] results in decreased activity of CAT protein; [Aluminum co-treated with Lead co-treated with Mercury co-treated with Manganese co-treated with Zinc] results in decreased activity of CAT protein; [Aluminum co-treated with Lead co-treated with Mercury co-treated with Manganese] results in decreased activity of CAT protein; [Arsenic co-treated with Cadmium co-treated with Lead co-treated with Mercury co-treated with Chromium co-treated with Nickel co-treated with Manganese co-treated with Iron] results in decreased activity of CAT protein; [Lead co-treated with Cadmium co-treated with Mercury co-treated with Arsenic] results in decreased expression of CAT protein; [Selenium co-treated with Zinc] inhibits the reaction [[Lead co-treated with Cadmium co-treated with Mercury co-treated with Arsenic] results in decreased expression of CAT protein]; Selenium affects the reaction [Mercury results in decreased activity of CAT protein]; Selenium inhibits the reaction [[Lead co-treated with Cadmium co-treated with Mercury co-treated with Arsenic] results in decreased expression of CAT protein]; Zinc inhibits the reaction [[Lead co-treated with Cadmium co-treated with Mercury co-treated with Arsenic] results in decreased expression of CAT protein] |
CTD |
PMID:17176674 PMID:20143455 PMID:37415728 PMID:37676925 |
|
NCBI chr 3:110,297,340...110,329,526
|
|
G |
Catsper2 |
cation channel, sperm associated 2 |
decreases expression |
ISO |
Mercury results in decreased expression of CATSPER2 mRNA |
CTD |
PMID:29549816 |
|
NCBI chr 3:108,368,654...108,389,380
|
|
G |
Cavin2 |
caveolae associated protein 2 |
decreases expression |
ISO |
Mercury analog results in decreased expression of CAVIN2 mRNA |
CTD |
PMID:25056781 |
|
NCBI chr 9:50,302,079...50,314,096
|
|
G |
Cbx7 |
chromobox 7 |
decreases expression |
ISO |
Mercury analog results in decreased expression of CBX7 mRNA |
CTD |
PMID:25056781 |
|
NCBI chr 7:113,341,030...113,358,716
|
|
G |
Ccl12 |
C-C motif chemokine ligand 12 |
increases expression |
ISO |
Mercury results in increased expression of CCL12 mRNA |
CTD |
PMID:30103553 |
|
NCBI chr10:67,567,876...67,569,426
|
|
G |
Ccl3 |
C-C motif chemokine ligand 3 |
increases expression multiple interactions |
EXP ISO |
Mercury results in increased expression of CCL3 mRNA MT3 protein affects the reaction [Mercury results in increased expression of CCL3 mRNA] |
CTD |
PMID:12730625 PMID:30103553 |
|
NCBI chr10:68,948,889...68,950,439
|
|
G |
Ccl7 |
C-C motif chemokine ligand 7 |
multiple interactions |
ISO |
[MT3 protein affects the susceptibility to Mercury] which affects the expression of CCL7 mRNA |
CTD |
PMID:30103553 |
|
NCBI chr10:67,514,095...67,515,945
|
|
G |
Ccnb2 |
cyclin B2 |
increases expression |
ISO |
Mercury results in increased expression of CCNB2 mRNA |
CTD |
PMID:17547211 |
|
NCBI chr 8:79,968,459...79,981,717
|
|
G |
Ccr2 |
C-C motif chemokine receptor 2 |
decreases expression |
ISO |
Mercury results in decreased expression of CCR2 mRNA |
CTD |
PMID:16823088 |
|
NCBI chr 8:132,611,883...132,619,106
|
|
G |
Cd226 |
CD226 molecule |
increases expression |
ISO |
Mercury results in increased expression of CD226 mRNA |
CTD |
PMID:16823088 |
|
NCBI chr18:82,449,924...82,545,107
|
|
G |
Cd40 |
CD40 molecule |
increases expression |
ISO |
Mercury results in increased expression of CD40 mRNA |
CTD |
PMID:16823088 |
|
NCBI chr 3:174,209,113...174,224,592
|
|
G |
Cd84 |
CD84 molecule |
decreases expression |
ISO |
Mercury results in decreased expression of CD84 mRNA |
CTD |
PMID:16823088 |
|
NCBI chr13:84,327,580...84,367,153
|
|
G |
Cdh1 |
cadherin 1 |
decreases expression |
ISO |
Mercury results in decreased expression of CDH1 mRNA |
CTD |
PMID:26600472 |
|
NCBI chr19:51,402,178...51,471,572
|
|
G |
Cdk5r1 |
cyclin-dependent kinase 5 regulatory subunit 1 |
increases expression |
ISO |
Mercury results in increased expression of CDK5R1 mRNA |
CTD |
PMID:16823088 |
|
NCBI chr10:65,981,692...65,985,831
|
|
G |
Cdkl2 |
cyclin dependent kinase like 2 |
decreases expression |
ISO |
Mercury analog results in decreased expression of CDKL2 mRNA |
CTD |
PMID:25056781 |
|
NCBI chr14:16,312,154...16,347,524
|
|
G |
Cdkn3 |
cyclin-dependent kinase inhibitor 3 |
increases expression |
ISO |
Mercury results in increased expression of CDKN3 mRNA |
CTD |
PMID:17547211 |
|
NCBI chr15:22,502,299...22,513,725
|
|
G |
Cebpd |
CCAAT/enhancer binding protein delta |
decreases expression |
ISO |
Mercury results in decreased expression of CEBPD mRNA |
CTD |
PMID:19937285 |
|
NCBI chr11:84,764,670...84,765,808
|
|
G |
Cfb |
complement factor B |
decreases expression affects expression |
ISO |
Mercury results in decreased expression of CFB mRNA Mercury affects the expression of CFB protein |
CTD |
PMID:17547211 PMID:22030286 |
|
NCBI chr20:3,970,643...3,976,510
|
|
G |
Cfd |
complement factor D |
increases expression |
ISO |
Mercury results in increased expression of CFD mRNA |
CTD |
PMID:16823088 |
|
NCBI chr 7:9,813,148...9,814,871
|
|
G |
Chac1 |
ChaC glutathione-specific gamma-glutamylcyclotransferase 1 |
decreases expression |
ISO |
Mercury analog results in decreased expression of CHAC1 mRNA |
CTD |
PMID:25056781 |
|
NCBI chr 3:126,796,131...126,799,352
|
|
G |
Chat |
choline O-acetyltransferase |
decreases expression |
EXP |
Mercury results in decreased expression of CHAT mRNA |
CTD |
PMID:7781173 |
|
NCBI chr16:7,657,362...7,717,093
|
|
G |
Cideb |
cell death-inducing DFFA-like effector b |
decreases expression |
ISO |
Mercury results in decreased expression of CIDEB mRNA |
CTD |
PMID:17547211 |
|
NCBI chr15:29,252,208...29,256,482
|
|
G |
Cks2 |
CDC28 protein kinase regulatory subunit 2 |
increases expression |
ISO |
Mercury results in increased expression of CKS2 mRNA |
CTD |
PMID:17547211 |
|
NCBI chr17:13,570,611...13,575,770
|
|
G |
Clasp2 |
cytoplasmic linker associated protein 2 |
increases expression |
ISO |
Mercury results in increased expression of CLASP2 mRNA |
CTD |
PMID:16823088 |
|
NCBI chr 8:122,555,532...122,736,934
|
|
G |
Clgn |
calmegin |
decreases expression |
ISO |
Mercury results in decreased expression of CLGN mRNA |
CTD |
PMID:17547211 |
|
NCBI chr19:24,695,140...24,728,542
|
|
G |
Clk1 |
CDC-like kinase 1 |
affects expression |
ISO |
Mercury affects the expression of CLK1 mRNA |
CTD |
PMID:16823088 |
|
NCBI chr 9:67,441,962...67,453,180
|
|
G |
Clptm1 |
CLPTM1 regulator of GABA type A receptor forward trafficking |
decreases expression increases expression |
ISO |
Mercury results in decreased expression of CLPTM1 mRNA Mercury results in increased expression of CLPTM1 mRNA |
CTD |
PMID:16823088 PMID:17547211 |
|
NCBI chr 1:79,289,478...79,321,079
|
|
G |
Cltc |
clathrin heavy chain |
decreases expression |
ISO |
Mercury results in decreased expression of CLTC mRNA |
CTD |
PMID:16823088 |
|
NCBI chr10:72,014,984...72,073,308
|
|
G |
Cmbl |
carboxymethylenebutenolidase homolog |
decreases expression |
ISO |
Mercury analog results in decreased expression of CMBL mRNA |
CTD |
PMID:25056781 |
|
NCBI chr 2:82,569,257...82,591,007
|
|
G |
Cnot3 |
CCR4-NOT transcription complex, subunit 3 |
increases expression |
ISO |
Mercury results in increased expression of CNOT3 mRNA |
CTD |
PMID:19937285 |
|
NCBI chr 1:74,471,284...74,487,527
|
|
G |
Col26a1 |
collagen type XXVI alpha 1 chain |
decreases methylation |
ISO |
Mercury results in decreased methylation of COL26A1 gene |
CTD |
PMID:25748564 |
|
NCBI chr12:19,792,693...19,938,556
|
|
G |
Col4a3 |
collagen type IV alpha 3 chain |
increases expression |
ISO |
Mercury results in increased expression of COL4A3 mRNA |
CTD |
PMID:16823088 |
|
NCBI chr 9:83,875,849...84,004,955
|
|
G |
Comt |
catechol-O-methyltransferase |
affects response to substance |
ISO |
COMT gene polymorphism affects the susceptibility to Mercury; COMT gene SNP affects the susceptibility to Mercury |
CTD |
PMID:19296409 PMID:24593143 |
|
NCBI chr11:96,072,371...96,091,956
|
|
G |
Cp |
ceruloplasmin |
affects expression |
ISO |
Mercury affects the expression of CP protein |
CTD |
PMID:22030286 |
|
NCBI chr 2:104,368,336...104,427,119
|
|
G |
Cpn2 |
carboxypeptidase N subunit 2 |
affects expression |
ISO |
Mercury affects the expression of CPN2 protein |
CTD |
PMID:22030286 |
|
NCBI chr11:70,486,054...70,495,937
|
|
G |
Cpox |
coproporphyrinogen oxidase |
affects response to substance multiple interactions decreases activity |
ISO |
CPOX polymorphism affects the susceptibility to Mercury; CPOX protein affects the susceptibility to Mercury; CPOX protein polymorphism affects the susceptibility to Mercury [Mercury results in decreased activity of CPOX protein] which results in increased abundance of Coproporphyrins; Mercury inhibits the reaction [CPOX protein results in decreased carboxylation of coproporphyrinogen III]; Mercury inhibits the reaction [CPOX protein results in increased chemical synthesis of protoporphyrinogen] |
CTD |
PMID:16214298 PMID:16343843 PMID:19339664 |
|
NCBI chr11:41,936,585...41,946,568
|
|
G |
Cpz |
carboxypeptidase Z |
increases expression |
ISO |
Mercury results in increased expression of CPZ mRNA |
CTD |
PMID:16823088 |
|
NCBI chr14:75,223,692...75,246,946
|
|
G |
Crip1 |
cysteine rich protein 1 |
decreases expression |
ISO |
Mercury analog results in decreased expression of CRIP1 mRNA |
CTD |
PMID:25056781 |
|
NCBI chr 6:132,226,746...132,234,620
|
|
G |
Cryaa |
crystallin, alpha A |
decreases expression |
ISO |
Mercury results in decreased expression of CRYAA mRNA |
CTD |
PMID:17547211 |
|
NCBI chr20:9,783,605...9,787,351
|
|
G |
Cryab |
crystallin, alpha B |
multiple interactions decreases response to substance increases expression |
ISO |
[arsenite co-treated with Cadmium] promotes the reaction [Mercury results in increased expression of CRYAB protein]; [arsenite co-treated with Mercury] promotes the reaction [Cadmium results in increased expression of CRYAB protein]; [Mercury co-treated with Cadmium] promotes the reaction [arsenite results in increased expression of CRYAB protein] CRYAB protein results in decreased susceptibility to Mercury |
CTD |
PMID:15590893 |
|
NCBI chr 8:59,989,885...59,995,532
|
|
G |
Cryz |
crystallin zeta |
multiple interactions increases activity |
ISO |
Mercury promotes the reaction [Benzo(a)pyrene results in increased activity of CRYZ protein]; Mercury promotes the reaction [Benzo(a)pyrene results in increased expression of CRYZ mRNA]; Mercury promotes the reaction [beta-Naphthoflavone results in increased activity of CRYZ protein]; Mercury promotes the reaction [beta-Naphthoflavone results in increased expression of CRYZ mRNA]; Mercury promotes the reaction [Methylcholanthrene results in increased activity of CRYZ protein]; Mercury promotes the reaction [Methylcholanthrene results in increased expression of CRYZ mRNA]; Mercury promotes the reaction [Tetrachlorodibenzodioxin results in increased activity of CRYZ protein]; Mercury promotes the reaction [Tetrachlorodibenzodioxin results in increased expression of CRYZ mRNA] Mercury results in increased activity of CRYZ protein |
CTD |
PMID:15297030 |
|
NCBI chr 2:246,211,707...246,239,472
|
|
G |
Cspg5 |
chondroitin sulfate proteoglycan 5 |
increases expression |
ISO |
Mercury results in increased expression of CSPG5 mRNA |
CTD |
PMID:16823088 |
|
NCBI chr 8:110,220,506...110,234,766
|
|
G |
Csrnp2 |
cysteine and serine rich nuclear protein 2 |
increases expression |
ISO |
Mercury results in increased expression of CSRNP2 mRNA |
CTD |
PMID:19937285 |
|
NCBI chr 7:131,594,232...131,610,075
|
|
G |
Cst3 |
cystatin C |
multiple interactions |
ISO |
[Metals, Heavy results in increased abundance of Mercury] which results in increased secretion of CST3 protein |
CTD |
PMID:39357351 |
|
NCBI chr 3:136,336,923...136,340,796
|
|
G |
Ctbp1 |
C-terminal binding protein 1 |
increases expression |
ISO |
Mercury results in increased expression of CTBP1 mRNA |
CTD |
PMID:16823088 |
|
NCBI chr14:77,455,580...77,482,821
|
|
G |
Ctsb |
cathepsin B |
increases activity |
ISO |
Mercury results in increased activity of CTSB protein |
CTD |
PMID:25237059 |
|
NCBI chr15:41,565,607...41,586,479
|
|
G |
Cul4b |
cullin 4B |
decreases expression |
ISO |
Mercury analog results in decreased expression of CUL4B mRNA |
CTD |
PMID:25056781 |
|
NCBI chr X:122,154,332...122,192,299
|
|
G |
Cyb561 |
cytochrome b-561 |
decreases expression |
ISO |
Mercury results in decreased expression of CYB561 mRNA |
CTD |
PMID:16823088 |
|
NCBI chr10:90,878,052...90,888,734
|
|
G |
Cyp1a1 |
cytochrome P450, family 1, subfamily a, polypeptide 1 |
multiple interactions increases stability increases activity increases expression |
ISO |
[Mercury co-treated with methylmercuric chloride] inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A1 mRNA]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde promotes the reaction [Mercury results in increased expression of CYP1A1 mRNA]; Buthionine Sulfoximine promotes the reaction [Mercury inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A1 protein]]; Cycloheximide promotes the reaction [Mercury results in increased expression of CYP1A1 mRNA]; Dactinomycin inhibits the reaction [Mercury results in increased expression of CYP1A1 mRNA]; Mercury affects the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A1 mRNA]; Mercury inhibits the reaction [Benzo(a)pyrene results in increased activity of CYP1A1 protein]; Mercury inhibits the reaction [beta-Naphthoflavone results in increased activity of CYP1A1 protein]; Mercury inhibits the reaction [Methylcholanthrene results in increased activity of CYP1A1 protein]; Mercury inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of CYP1A1 protein]; Mercury inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of and results in increased activity of CYP1A1 protein]; Mercury inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A1 mRNA]; Mercury inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A1 protein]; Mercury promotes the reaction [Benzo(a)pyrene results in increased expression of CYP1A1 mRNA]; Mercury promotes the reaction [Benzo(a)pyrene results in increased expression of CYP1A1 protein]; Mercury promotes the reaction [beta-Naphthoflavone results in increased expression of CYP1A1 mRNA]; Mercury promotes the reaction [beta-Naphthoflavone results in increased expression of CYP1A1 protein]; Mercury promotes the reaction [Methylcholanthrene results in increased expression of CYP1A1 mRNA]; Mercury promotes the reaction [Methylcholanthrene results in increased expression of CYP1A1 protein]; Mercury promotes the reaction [Tetrachlorodibenzodioxin results in increased activity of CYP1A1 protein]; Mercury promotes the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A1 mRNA]; Mercury promotes the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A1 protein]; pyrazolanthrone inhibits the reaction [Mercury results in increased expression of CYP1A1 mRNA]; pyrazolanthrone promotes the reaction [Mercury inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A1 protein]]; pyrrolidine dithiocarbamic acid inhibits the reaction [Mercury inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A1 protein]]; pyrrolidine dithiocarbamic acid promotes the reaction [Mercury results in increased expression of CYP1A1 mRNA]; Tetradecanoylphorbol Acetate inhibits the reaction [Mercury results in increased expression of CYP1A1 mRNA]; Tetradecanoylphorbol Acetate promotes the reaction [Mercury inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A1 protein]]; U 0126 inhibits the reaction [Mercury inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A1 protein]]; U 0126 promotes the reaction [Mercury results in increased expression of CYP1A1 mRNA] Mercury results in increased stability of CYP1A1 protein Mercury results in increased activity of CYP1A1 protein |
CTD |
PMID:15297030 PMID:16093525 PMID:18078826 PMID:22579925 PMID:23231920 PMID:36245390 More...
|
|
NCBI chr 8:66,991,940...66,998,014
|
|
G |
Cyp1a2 |
cytochrome P450, family 1, subfamily a, polypeptide 2 |
multiple interactions increases activity |
ISO |
[Mercury co-treated with methylmercuric chloride] inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A2 mRNA]; Mercury affects the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A2 mRNA]; Mercury inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of CYP1A2 protein]; Mercury inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of and results in increased activity of CYP1A2 protein]; Mercury promotes the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A2 mRNA] Mercury results in increased activity of CYP1A2 protein |
CTD |
PMID:22579925 PMID:23231920 PMID:36245390 |
|
NCBI chr 8:66,971,261...66,978,149
|
|
G |
Cyp1b1 |
cytochrome P450, family 1, subfamily b, polypeptide 1 |
multiple interactions increases expression |
ISO |
Mercury affects the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1B1 mRNA]; Mercury inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1B1 protein]; Mercury promotes the reaction [Tetrachlorodibenzodioxin results in increased activity of CYP1B1 protein]; Mercury promotes the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1B1 mRNA]; Mercury promotes the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1B1 protein] Mercury results in increased expression of CYP1B1 protein |
CTD |
PMID:22579925 PMID:23231920 |
|
NCBI chr 6:21,093,927...21,103,091
|
|
G |
Cyp2u1 |
cytochrome P450, family 2, subfamily u, polypeptide 1 |
increases expression |
ISO |
Mercury results in increased expression of CYP2U1 mRNA |
CTD |
PMID:16823088 |
|
NCBI chr 2:219,849,403...219,866,959
|
|
G |
Cyp7a1 |
cytochrome P450 family 7 subfamily A member 1 |
decreases activity |
EXP |
Mercury results in decreased activity of CYP7A1 protein |
CTD |
PMID:1175606 |
|
NCBI chr 5:24,174,505...24,184,202
|
|
G |
Dab1 |
DAB adaptor protein 1 |
increases expression |
ISO |
Mercury results in increased expression of DAB1 mRNA |
CTD |
PMID:16823088 |
|
NCBI chr 5:118,392,953...119,513,625
|
|
G |
Dcx |
doublecortin |
multiple interactions |
ISO |
[diethyl phosphate co-treated with Cotinine co-treated with bis(2,3,3,3-tetrachloropropyl) ether co-treated with Mercury co-treated with Selenium] results in increased expression of DCX mRNA |
CTD |
PMID:37914285 |
|
NCBI chr X:107,430,767...107,573,612
|
|
G |
Def8 |
differentially expressed in FDCP 8 homolog |
decreases expression |
ISO |
Mercury results in decreased expression of DEF8 mRNA |
CTD |
PMID:22008530 |
|
NCBI chr19:51,474,783...51,495,638
|
|
G |
Diras1 |
DIRAS family GTPase 1 |
decreases expression |
ISO |
Mercury results in decreased expression of DIRAS1 mRNA |
CTD |
PMID:19937285 |
|
NCBI chr 7:8,687,964...8,692,828
|
|
G |
Dnah1 |
dynein, axonemal, heavy chain 1 |
decreases expression |
ISO |
Mercury results in decreased expression of DNAH1 mRNA |
CTD |
PMID:16823088 |
|
NCBI chr16:6,455,514...6,517,103
|
|
G |
Dnaja2 |
DnaJ heat shock protein family (Hsp40) member A2 |
increases expression |
EXP |
Mercury results in increased expression of DNAJA2 mRNA |
CTD |
PMID:22688007 |
|
NCBI chr19:21,497,792...21,516,904
|
|
G |
Dock10 |
dedicator of cytokinesis 10 |
increases expression |
ISO |
Mercury results in increased expression of DOCK10 mRNA |
CTD |
PMID:16823088 |
|
NCBI chr 9:81,843,599...82,101,540
|
|
G |
Dpysl4 |
dihydropyrimidinase-like 4 |
increases expression |
ISO |
Mercury results in increased expression of DPYSL4 mRNA |
CTD |
PMID:16823088 |
|
NCBI chr 1:193,883,039...193,898,916
|
|
G |
Drd3 |
dopamine receptor D3 |
multiple interactions |
EXP |
Mercury inhibits the reaction [3-N-methylspiperone binds to DRD3 protein] |
CTD |
PMID:10215675 |
|
NCBI chr11:70,385,586...70,437,793
|
|
G |
Drd4 |
dopamine receptor D4 |
multiple interactions |
EXP |
Mercury inhibits the reaction [3-N-methylspiperone binds to DRD4 protein] |
CTD |
PMID:10215675 |
|
NCBI chr 1:205,825,937...205,829,124
|
|
G |
Dtna |
dystrobrevin, alpha |
increases expression |
ISO |
Mercury results in increased expression of DTNA mRNA |
CTD |
PMID:16823088 |
|
NCBI chr18:14,687,193...14,944,232
|
|
G |
Eea1 |
early endosome antigen 1 |
increases expression |
ISO |
Mercury results in increased expression of EEA1 mRNA |
CTD |
PMID:16823088 |
|
NCBI chr 7:30,554,686...30,722,186
|
|
G |
Efnb1 |
ephrin B1 |
increases expression |
ISO |
Mercury results in increased expression of EFNB1 mRNA |
CTD |
PMID:16823088 |
|
NCBI chr X:64,257,351...64,270,158
|
|
G |
Eif2ak1 |
eukaryotic translation initiation factor 2 alpha kinase 1 |
decreases activity multiple interactions |
ISO |
Mercury results in decreased activity of EIF2AK1 protein Nitric Oxide inhibits the reaction [Mercury results in decreased activity of EIF2AK1 protein] |
CTD |
PMID:17689536 |
|
NCBI chr12:15,824,431...15,858,266
|
|
G |
Eif3f |
eukaryotic translation initiation factor 3, subunit F |
decreases expression |
ISO |
Mercury results in decreased expression of EIF3F mRNA |
CTD |
PMID:16823088 |
|
NCBI chr 1:162,934,220...162,943,204
|
|
G |
Eif4g1 |
eukaryotic translation initiation factor 4 gamma 1 |
decreases expression |
ISO |
Mercury analog results in decreased expression of EIF4G1 mRNA |
CTD |
PMID:25056781 |
|
NCBI chr11:93,726,322...93,746,387
|
|
G |
Elp1 |
elongator acetyltransferase complex subunit 1 |
decreases expression |
ISO |
Mercury results in decreased expression of ELP1 mRNA |
CTD |
PMID:16823088 |
|
NCBI chr 5:76,248,545...76,300,985
|
|
G |
Emx2 |
empty spiracles homeobox 2 |
increases expression |
ISO |
Mercury results in increased expression of EMX2 mRNA |
CTD |
PMID:16823088 |
|
NCBI chr 1:258,626,584...258,633,594
|
|
G |
En1 |
engrailed homeobox 1 |
increases expression |
ISO |
Mercury results in increased expression of EN1 mRNA |
CTD |
PMID:16823088 |
|
NCBI chr13:31,750,892...31,756,477
|
|
G |
Enpp1 |
ectonucleotide pyrophosphatase/phosphodiesterase 1 |
increases expression |
ISO |
Mercury results in increased expression of ENPP1 mRNA |
CTD |
PMID:17547211 |
|
NCBI chr 1:22,518,051...22,583,044
|
|
G |
Epo |
erythropoietin |
multiple interactions |
EXP |
EPO protein affects the reaction [Mercury affects the localization of SLC22A8 protein]; EPO protein inhibits the reaction [Mercury results in increased expression of SLC22A19 protein]; EPO protein promotes the reaction [Mercury results in increased expression of and affects the localization of ABCC2 protein]; EPO protein promotes the reaction [Mercury results in increased expression of and affects the localization of SLC22A6 protein]; EPO protein promotes the reaction [Mercury results in increased expression of SLC22A8 protein] |
CTD |
PMID:32909846 |
|
NCBI chr12:19,204,258...19,207,948
|
|
G |
Esr2 |
estrogen receptor 2 |
increases expression |
ISO |
Mercury results in increased expression of ESR2 mRNA |
CTD |
PMID:16823088 |
|
NCBI chr 6:100,589,553...100,645,240
|
|
G |
Etfb |
electron transfer flavoprotein subunit beta |
increases expression |
ISO |
Mercury results in increased expression of ETFB mRNA |
CTD |
PMID:16823088 |
|
NCBI chr 1:102,988,499...103,002,663
|
|
G |
Ets2 |
ETS proto-oncogene 2, transcription factor |
increases expression |
ISO |
Mercury results in increased expression of ETS2 mRNA |
CTD |
PMID:17547211 |
|
NCBI chr11:48,491,057...48,507,843
|
|
G |
Ezh1 |
enhancer of zeste 1 polycomb repressive complex 2 subunit |
increases expression |
ISO |
Mercury results in increased expression of EZH1 mRNA |
CTD |
PMID:16823088 |
|
NCBI chr10:86,126,023...86,162,001
|
|
G |
F10 |
coagulation factor X |
decreases expression |
ISO |
Mercury results in decreased expression of F10 mRNA |
CTD |
PMID:17547211 |
|
NCBI chr16:83,170,973...83,190,280
|
|
G |
F5 |
coagulation factor V |
decreases expression |
ISO |
Mercury results in decreased expression of F5 mRNA |
CTD |
PMID:17547211 |
|
NCBI chr13:79,046,657...79,116,247
|
|
G |
Fabp5 |
fatty acid binding protein 5 |
increases expression |
EXP |
Mercury results in increased expression of FABP5 mRNA |
CTD |
PMID:12730625 |
|
NCBI chr 2:91,765,056...91,768,716
|
|
G |
Fabp7 |
fatty acid binding protein 7 |
increases expression |
ISO |
Mercury results in increased expression of FABP7 mRNA |
CTD |
PMID:16823088 |
|
NCBI chr20:37,123,193...37,126,725
|
|
G |
Fam184b |
family with sequence similarity 184, member B |
decreases expression |
ISO |
Mercury analog results in decreased expression of FAM184B mRNA |
CTD |
PMID:25056781 |
|
NCBI chr14:65,475,489...65,591,388
|
|
G |
Fas |
Fas cell surface death receptor |
multiple interactions |
ISO |
Mercury inhibits the reaction [FAS protein binds to FAS protein] |
CTD |
PMID:16039944 |
|
NCBI chr 1:241,212,155...241,245,774
|
|
G |
Fcer1g |
Fc epsilon receptor Ig |
affects response to substance |
ISO |
FCER1G protein affects the susceptibility to Mercury |
CTD |
PMID:20976163 |
|
NCBI chr13:86,181,908...86,186,766
|
|
G |
Fcgr1a |
Fc gamma receptor 1A |
multiple interactions |
ISO |
[Mercuric Chloride results in increased abundance of Mercury] which results in increased expression of FCGR1 mRNA; IFNG gene mutant form inhibits the reaction [[Mercuric Chloride results in increased abundance of Mercury] which results in increased expression of FCGR1 mRNA]; IL6 gene mutant form inhibits the reaction [[Mercuric Chloride results in increased abundance of Mercury] which results in increased expression of FCGR1 mRNA] |
CTD |
PMID:28453771 |
|
NCBI chr 2:186,539,941...186,548,941
|
|
G |
Fcgr3a |
Fc gamma receptor 3A |
decreases expression |
ISO |
Mercury results in decreased expression of FCGR3A mRNA |
CTD |
PMID:16823088 |
|
NCBI chr13:85,782,636...85,792,656
|
|
G |
Fcrla |
Fc receptor-like A |
decreases expression |
ISO |
Mercury results in decreased expression of FCRLA mRNA |
CTD |
PMID:16823088 |
|
NCBI chr13:83,160,453...83,170,170
|
|
G |
Fech |
ferrochelatase |
decreases activity |
ISO |
Mercury results in decreased activity of FECH protein |
CTD |
PMID:2347080 |
|
NCBI chr18:57,945,123...57,978,327
|
|
G |
Ferd3l |
Fer3-like bHLH transcription factor |
decreases expression |
ISO |
Mercury results in decreased expression of FERD3L mRNA |
CTD |
PMID:19937285 |
|
NCBI chr 6:50,645,379...50,646,268
|
|
G |
Fgf2 |
fibroblast growth factor 2 |
increases expression |
ISO |
Mercury results in increased expression of FGF2 mRNA |
CTD |
PMID:16823088 |
|
NCBI chr 2:122,164,454...122,218,796
|
|
G |
Flnb |
filamin B |
increases expression |
ISO |
Mercury results in increased expression of FLNB mRNA |
CTD |
PMID:19937285 |
|
NCBI chr15:16,961,999...17,095,059
|
|
G |
Fn1 |
fibronectin 1 |
decreases expression |
ISO |
Mercury results in decreased expression of FN1 mRNA |
CTD |
PMID:16823088 |
|
NCBI chr 9:80,645,507...80,714,200
|
|
G |
Fos |
Fos proto-oncogene, AP-1 transcription factor subunit |
multiple interactions |
EXP |
Mercury promotes the reaction [HSPA5 protein binds to FOS enhancer] |
CTD |
PMID:15111246 |
|
NCBI chr 6:110,852,188...110,855,054
|
|
G |
Fosl1 |
FOS like 1, AP-1 transcription factor subunit |
increases expression |
ISO |
Mercury results in increased expression of FOSL1 mRNA |
CTD |
PMID:17547211 |
|
NCBI chr 1:212,183,885...212,192,391
|
|
G |
Foxi1 |
forkhead box I1 |
decreases expression |
ISO |
Mercury results in decreased expression of FOXI1 mRNA |
CTD |
PMID:19937285 |
|
NCBI chr10:18,806,292...18,810,231
|
|
G |
Foxk1 |
forkhead box K1 |
increases expression |
ISO |
Mercury results in increased expression of FOXK1 mRNA |
CTD |
PMID:19937285 |
|
NCBI chr12:12,110,119...12,175,089
|
|
G |
Frmd6 |
FERM domain containing 6 |
decreases expression |
ISO |
Mercury analog results in decreased expression of FRMD6 mRNA |
CTD |
PMID:25056781 |
|
NCBI chr 6:89,345,983...89,419,579
|
|
G |
Furin |
furin (paired basic amino acid cleaving enzyme) |
decreases expression |
ISO |
Mercury results in decreased expression of FURIN mRNA |
CTD |
PMID:17547211 |
|
NCBI chr 1:143,757,389...143,770,430
|
|
G |
G6pd |
glucose-6-phosphate dehydrogenase |
decreases activity |
ISO |
Mercury results in decreased activity of G6PD protein |
CTD |
PMID:10798623 |
|
NCBI chr X:157,352,364...157,372,144
|
|
G |
Gabra6 |
gamma-aminobutyric acid type A receptor subunit alpha6 |
increases expression |
ISO |
Mercury results in increased expression of GABRA6 mRNA |
CTD |
PMID:16823088 |
|
NCBI chr10:26,810,411...26,825,768
|
|
G |
Gas7 |
growth arrest specific 7 |
increases expression |
ISO |
Mercury results in increased expression of GAS7 mRNA |
CTD |
PMID:16823088 |
|
NCBI chr10:52,651,690...52,882,244
|
|
G |
Gatad2b |
GATA zinc finger domain containing 2B |
decreases expression |
ISO |
Mercury analog results in decreased expression of GATAD2B mRNA |
CTD |
PMID:25056781 |
|
NCBI chr 2:178,046,192...178,127,633
|
|
G |
Gclc |
glutamate-cysteine ligase, catalytic subunit |
increases expression affects response to substance multiple interactions |
ISO EXP |
Mercury results in increased expression of GCLC mRNA GCLC gene SNP affects the susceptibility to Mercury [Mercuric Chloride results in increased abundance of Mercury] which results in decreased expression of GCLC protein; GCLC gene polymorphism promotes the reaction [GSTP1 gene polymorphism affects the abundance of Mercury] [Mercuric Chloride results in increased abundance of Mercury] which results in increased expression of GCLC mRNA; [Mercuric Chloride results in increased abundance of Mercury] which results in increased expression of GCLC protein; Curcumin promotes the reaction [[Mercuric Chloride results in increased abundance of Mercury] which results in increased expression of GCLC mRNA]; Curcumin promotes the reaction [[Mercuric Chloride results in increased abundance of Mercury] which results in increased expression of GCLC protein] |
CTD |
PMID:17547211 PMID:19515364 PMID:22236634 PMID:27837179 PMID:30359721 |
|
NCBI chr 8:87,510,251...87,548,896
|
|
G |
Gclm |
glutamate cysteine ligase, modifier subunit |
decreases expression affects abundance affects metabolic processing |
ISO |
Mercury results in decreased expression of GCLM mRNA GCLM gene polymorphism affects the abundance of Mercury; GCLM protein affects the abundance of Mercury GCLM polymorphism affects the metabolism of Mercury |
CTD |
PMID:16961004 PMID:18560528 PMID:19937285 PMID:21925580 |
|
NCBI chr 2:213,032,135...213,052,192
|
|
G |
Ggcx |
gamma-glutamyl carboxylase |
decreases expression |
ISO |
Mercury results in decreased expression of GGCX mRNA |
CTD |
PMID:17547211 |
|
NCBI chr 4:106,027,918...106,043,653
|
|
G |
Ggt1 |
gamma-glutamyltransferase 1 |
decreases expression multiple interactions |
ISO EXP |
Mercury results in decreased expression of GGT1 mRNA [Zinc co-treated with Copper co-treated with Manganese co-treated with Potassium Dichromate co-treated with Nickel co-treated with Cadmium co-treated with Lead co-treated with Mercury] affects the expression of GGT1 protein |
CTD |
PMID:19937285 PMID:30090589 |
|
NCBI chr20:13,074,695...13,104,095
|
|
G |
Gla |
galactosidase, alpha |
increases expression |
ISO |
Mercury results in increased expression of GLA mRNA |
CTD |
PMID:17547211 |
|
NCBI chr X:102,062,497...102,073,915
|
|
G |
Glra3 |
glycine receptor, alpha 3 |
increases expression |
ISO |
Mercury results in increased expression of GLRA3 mRNA |
CTD |
PMID:16823088 |
|
NCBI chr16:34,199,937...34,848,773
|
|
G |
Gmppb |
GDP-mannose pyrophosphorylase B |
decreases expression |
ISO |
Mercury analog results in decreased expression of GMPPB mRNA |
CTD |
PMID:25056781 |
|
NCBI chr 8:117,616,029...117,622,866
|
|
G |
Gngt1 |
G protein subunit gamma transducin 1 |
increases expression |
ISO |
Mercury results in increased expression of GNGT1 mRNA |
CTD |
PMID:16823088 |
|
NCBI chr 4:32,006,267...32,009,252
|
|
G |
Gnrh1 |
gonadotropin releasing hormone 1 |
increases expression |
ISO |
Mercury results in increased expression of GNRH1 mRNA |
CTD |
PMID:16823088 |
|
NCBI chr15:41,972,482...41,976,690
|
|
G |
Golga1 |
golgin A1 |
decreases expression |
ISO |
Mercury analog results in decreased expression of GOLGA1 mRNA |
CTD |
PMID:25056781 |
|
NCBI chr 3:22,765,690...22,812,637
|
|
G |
Golga3 |
golgin A3 |
decreases expression |
ISO |
Mercury analog results in decreased expression of GOLGA3 mRNA |
CTD |
PMID:25056781 |
|
NCBI chr12:46,452,409...46,500,509
|
|
G |
Gorasp1 |
golgi reassembly stacking protein 1 |
decreases expression |
ISO |
Mercury analog results in decreased expression of GORASP1 mRNA |
CTD |
PMID:25056781 |
|
NCBI chr 8:119,655,267...119,667,022
|
|
G |
Gper1 |
G protein-coupled estrogen receptor 1 |
decreases expression |
ISO |
Mercury results in decreased expression of GPER1 mRNA |
CTD |
PMID:17547211 |
|
NCBI chr12:15,217,217...15,222,679
|
|
G |
Gpt |
glutamic--pyruvic transaminase |
multiple interactions |
EXP |
[Lead co-treated with Cadmium co-treated with Mercury co-treated with Arsenic] results in increased expression of GPT protein; [Selenium co-treated with Zinc] inhibits the reaction [[Lead co-treated with Cadmium co-treated with Mercury co-treated with Arsenic] results in increased expression of GPT protein]; Selenium inhibits the reaction [[Lead co-treated with Cadmium co-treated with Mercury co-treated with Arsenic] results in increased expression of GPT protein]; Zinc inhibits the reaction [[Lead co-treated with Cadmium co-treated with Mercury co-treated with Arsenic] results in increased expression of GPT protein] |
CTD |
PMID:37676925 |
|
NCBI chr 7:110,295,599...110,300,134
|
|
G |
Gpx1 |
glutathione peroxidase 1 |
affects response to substance increases expression |
ISO |
GPX1 gene SNP affects the susceptibility to Mercury Mercury results in increased expression of GPX1 protein |
CTD |
PMID:16451871 PMID:22236634 |
|
NCBI chr 8:117,905,462...117,906,588
|
|
G |
Gsn |
gelsolin |
decreases expression affects expression |
ISO |
Mercury results in decreased expression of GSN mRNA Mercury affects the expression of GSN protein |
CTD |
PMID:17547211 PMID:22030286 |
|
NCBI chr 3:38,982,605...39,035,849
|
|
G |
Gsr |
glutathione-disulfide reductase |
decreases activity multiple interactions |
ISO EXP |
Mercury results in decreased activity of GSR protein [Arsenic co-treated with Cadmium co-treated with Lead co-treated with Mercury co-treated with Chromium co-treated with Nickel co-treated with Manganese co-treated with Iron] results in decreased activity of GSR protein |
CTD |
PMID:10798623 PMID:17176674 |
|
NCBI chr16:65,185,574...65,228,742
|
|
G |
Gss |
glutathione synthetase |
affects abundance |
ISO |
GSS gene polymorphism affects the abundance of Mercury |
CTD |
PMID:21967774 |
|
NCBI chr 3:144,047,849...144,078,197
|
|
G |
Gsta1 |
glutathione S-transferase alpha 1 |
affects abundance |
ISO |
GSTA1 gene polymorphism affects the abundance of Mercury |
CTD |
PMID:19515364 |
|
NCBI chr 9:23,703,476...23,720,121
|
|
G |
Gsta2 |
glutathione S-transferase alpha 2 |
increases expression |
EXP |
Mercury results in increased expression of GSTA2 mRNA |
CTD |
PMID:12167210 |
|
NCBI chr 8:79,184,535...79,196,827
|
|
G |
Gstm1 |
glutathione S-transferase mu 1 |
affects response to substance multiple interactions affects abundance |
ISO |
GSTM1 gene polymorphism affects the susceptibility to Mercury; GSTM1 polymorphism affects the susceptibility to Mercury [GSTM1 gene polymorphism co-treated with GSTT1 gene polymorphism] affects the susceptibility to Mercury; [GSTP1 gene polymorphism co-treated with GSTM1 gene polymorphism] affects the abundance of Mercury; [Mercuric Chloride results in increased abundance of Mercury] which results in decreased expression of GSTM1 protein GSTM1 gene polymorphism affects the abundance of Mercury |
CTD |
PMID:17716707 PMID:19515364 PMID:20194072 PMID:24319713 PMID:25728017 PMID:30359721 More...
|
|
NCBI chr 2:198,338,005...198,346,007
|
|
G |
Gstp1 |
glutathione S-transferase pi 1 |
increases expression affects abundance multiple interactions |
EXP ISO |
Mercury results in increased expression of GSTP1 mRNA; Mercury results in increased expression of GSTP1 protein GSTP1 gene affects the abundance of Mercury; GSTP1 gene polymorphism affects the abundance of Mercury [GSTP1 gene polymorphism co-treated with GSTM1 gene polymorphism] affects the abundance of Mercury; GCLC gene polymorphism promotes the reaction [GSTP1 gene polymorphism affects the abundance of Mercury]; GSTT1 gene polymorphism promotes the reaction [GSTP1 gene polymorphism affects the abundance of Mercury] [Mercuric Chloride results in increased abundance of Mercury] which results in increased expression of GSTP1 mRNA; [Mercuric Chloride results in increased abundance of Mercury] which results in increased expression of GSTP1 protein |
CTD |
PMID:12167210 PMID:12730625 PMID:18560528 PMID:19515364 PMID:21967774 PMID:29298499 More...
|
|
NCBI chr 1:210,767,237...210,770,242
|
|
G |
Gstt1 |
glutathione S-transferase theta 1 |
affects abundance multiple interactions affects response to substance |
ISO |
GSTT1 gene polymorphism affects the abundance of Mercury [GSTM1 gene polymorphism co-treated with GSTT1 gene polymorphism] affects the susceptibility to Mercury; GSTT1 gene polymorphism promotes the reaction [GSTP1 gene polymorphism affects the abundance of Mercury] GSTT1 gene polymorphism affects the susceptibility to Mercury; GSTT1 polymorphism affects the susceptibility to Mercury |
CTD |
PMID:17716707 PMID:19515364 PMID:20194072 PMID:21967774 PMID:24319713 |
|
NCBI chr20:12,856,068...12,873,020
|
|
G |
Gtpbp8 |
GTP binding protein 8 |
decreases expression |
ISO |
Mercury analog results in decreased expression of GTPBP8 mRNA |
CTD |
PMID:25056781 |
|
NCBI chr11:55,945,778...55,955,743
|
|
G |
Gxylt2 |
glucoside xylosyltransferase 2 |
decreases expression |
ISO |
Mercury analog results in decreased expression of GXYLT2 mRNA |
CTD |
PMID:25056781 |
|
NCBI chr 4:133,347,230...133,449,708
|
|
G |
Habp4 |
hyaluronan binding protein 4 |
increases expression |
ISO |
Mercury results in increased expression of HABP4 mRNA |
CTD |
PMID:16823088 |
|
NCBI chr17:934,931...957,604
|
|
G |
Hamp |
hepcidin antimicrobial peptide |
multiple interactions |
ISO |
[HAMP protein results in decreased expression of SLC11A2 mRNA] which results in decreased uptake of Mercury |
CTD |
PMID:25772431 |
|
NCBI chr 1:95,298,332...95,300,271
|
|
G |
Havcr1 |
hepatitis A virus cellular receptor 1 |
increases expression |
EXP |
Mercury results in increased expression of HAVCR1 mRNA; Mercury results in increased expression of HAVCR1 protein |
CTD |
PMID:17934191 PMID:25145654 |
|
NCBI chr10:31,118,667...31,151,730
|
|
G |
Heph |
hephaestin |
increases expression |
ISO |
Mercury results in increased expression of HEPH mRNA |
CTD |
PMID:16823088 |
|
NCBI chr X:65,160,628...65,412,457
|
|
G |
Hif3a |
hypoxia inducible factor 3 subunit alpha |
decreases expression |
ISO |
Mercury results in decreased expression of HIF3A mRNA |
CTD |
PMID:19937285 |
|
NCBI chr 1:77,718,110...77,750,448
|
|
G |
Hint3 |
histidine triad nucleotide binding protein 3 |
decreases expression |
ISO |
Mercury analog results in decreased expression of HINT3 mRNA |
CTD |
PMID:25056781 |
|
NCBI chr 1:28,854,860...28,864,723
|
|
G |
Hist1h2ah |
histone cluster 1 H2A family member H |
increases expression |
ISO |
Mercury results in increased expression of H2AC11 mRNA |
CTD |
PMID:16823088 |
|
NCBI chr17:41,812,378...41,812,875
|
|
G |
Hmgn2 |
high mobility group nucleosomal binding domain 2 |
increases expression |
ISO |
Mercury results in increased expression of HMGN2 mRNA |
CTD |
PMID:17547211 |
|
NCBI chr 5:146,192,126...146,195,580
|
|
G |
Hmox1 |
heme oxygenase 1 |
multiple interactions increases expression |
ISO EXP |
Acetylcysteine inhibits the reaction [Mercury results in increased expression of HMOX1 mRNA]; Mercury promotes the reaction [HSF1 protein binds to HMOX1 promoter] [Benzo(a)pyrene co-treated with Mercury] results in increased expression of HMOX1 mRNA; [beta-Naphthoflavone co-treated with Mercury] results in increased expression of HMOX1 mRNA; [Mercury co-treated with Tetrachlorodibenzodioxin] results in increased expression of HMOX1 protein; [Methylcholanthrene co-treated with Mercury] results in increased expression of HMOX1 mRNA; [Tetrachlorodibenzodioxin co-treated with Mercury] results in increased expression of HMOX1 mRNA; Mercury inhibits the reaction [Tetrachlorodibenzodioxin results in decreased expression of HMOX1 protein]; Mercury promotes the reaction [Tetrachlorodibenzodioxin results in increased expression of HMOX1 mRNA]; Mercury results in increased expression of and results in increased activity of HMOX1 protein; pyrazolanthrone inhibits the reaction [Mercury results in increased expression of HMOX1 mRNA]; pyrrolidine dithiocarbamic acid promotes the reaction [Mercury results in increased expression of HMOX1 mRNA]; SB 203580 inhibits the reaction [Mercury results in increased expression of HMOX mRNA]; Tetrachlorodibenzodioxin promotes the reaction [Mercury results in increased expression of HMOX1 mRNA]; Tetradecanoylphorbol Acetate inhibits the reaction [Mercury results in increased expression of HMOX1 mRNA]; U 0126 promotes the reaction [Mercury results in increased expression of HMOX1 mRNA] [Mercuric Chloride results in increased abundance of Mercury] which results in increased expression of HMOX1 mRNA; [Mercuric Chloride results in increased abundance of Mercury] which results in increased expression of HMOX1 protein; Curcumin promotes the reaction [[Mercuric Chloride results in increased abundance of Mercury] which results in increased expression of HMOX1 mRNA]; Curcumin promotes the reaction [[Mercuric Chloride results in increased abundance of Mercury] which results in increased expression of HMOX1 protein] |
CTD |
PMID:12730625 PMID:15297030 PMID:16093525 PMID:17244614 PMID:17547211 PMID:18078826 PMID:22579925 PMID:23231920 PMID:26600472 PMID:27837179 PMID:36245390 More...
|
|
NCBI chr19:13,452,365...13,479,823
|
|
G |
Hnf1a |
HNF1 homeobox A |
increases expression |
ISO |
Mercury results in increased expression of HNF1A mRNA |
CTD |
PMID:16823088 |
|
NCBI chr12:47,299,171...47,333,457
|
|
G |
Hnrnph3 |
heterogeneous nuclear ribonucleoprotein H3 |
increases expression |
ISO |
Mercury results in increased expression of HNRNPH3 mRNA |
CTD |
PMID:16823088 |
|
NCBI chr20:25,616,400...25,625,814
|
|
G |
Hoxb4 |
homeo box B4 |
increases expression |
ISO |
Mercury results in increased expression of HOXB4 mRNA |
CTD |
PMID:19937285 |
|
NCBI chr10:81,284,552...81,287,134
|
|
G |
Hoxb6 |
homeo box B6 |
increases expression |
ISO |
Mercury results in increased expression of HOXB6 mRNA |
CTD |
PMID:16823088 |
|
NCBI chr10:81,755,263...81,763,999
|
|
G |
Hpx |
hemopexin |
affects expression |
ISO |
Mercury affects the expression of HPX protein |
CTD |
PMID:22030286 |
|
NCBI chr 1:159,932,819...159,940,327
|
|
G |
Hras |
HRas proto-oncogene, GTPase |
multiple interactions |
EXP |
Mercury promotes the reaction [HSPA5 protein binds to HRAS enhancer] |
CTD |
PMID:15111246 |
|
NCBI chr 1:205,712,625...205,729,406
|
|
G |
Hs1bp3 |
HCLS1 binding protein 3 |
decreases expression |
ISO |
Mercury results in decreased expression of HS1BP3 mRNA |
CTD |
PMID:16823088 |
|
NCBI chr 6:31,192,568...31,222,835
|
|
G |
Hsf1 |
heat shock transcription factor 1 |
multiple interactions increases activity |
ISO |
Mercury promotes the reaction [HSF1 protein binds to HMOX1 promoter]; Mercury promotes the reaction [HSF1 protein binds to HSPA1A promoter] Mercury results in increased activity of HSF1 protein |
CTD |
PMID:17244614 |
|
NCBI chr 7:110,076,710...110,103,665
|
|
G |
Hsf2 |
heat shock transcription factor 2 |
decreases expression |
ISO |
Mercury results in decreased expression of HSF2 mRNA |
CTD |
PMID:22008530 |
|
NCBI chr20:37,366,301...37,393,922
|
|
G |
Hsp90aa1 |
heat shock protein 90 alpha family class A member 1 |
increases expression |
ISO |
Mercury results in increased expression of HSP90AA1 mRNA |
CTD |
PMID:16823088 |
|
NCBI chr 6:135,523,604...135,529,687
|
|
G |
Hspa1a |
heat shock protein family A (Hsp70) member 1A |
multiple interactions increases expression |
ISO |
Mercury promotes the reaction [HSF1 protein binds to HSPA1A promoter] Mercury results in increased expression of HSPA1A mRNA |
CTD |
PMID:17244614 |
|
NCBI chr20:3,875,411...3,877,866
|
|
G |
Hspa1b |
heat shock protein family A (Hsp70) member 1B |
affects response to substance |
ISO |
HSPA1B gene polymorphism affects the susceptibility to Mercury |
CTD |
PMID:23330093 |
|
NCBI chr20:3,859,756...3,863,800
|
|
G |
Hspa1l |
heat shock protein family A (Hsp70) member 1 like |
affects response to substance |
ISO |
HSPA1L gene polymorphism affects the susceptibility to Mercury |
CTD |
PMID:23330093 |
|
NCBI chr20:3,848,843...3,855,571
|
|
G |
Hspa5 |
heat shock protein family A (Hsp70) member 5 |
affects expression multiple interactions |
EXP |
Mercury affects the expression of HSPA5 mRNA Mercury promotes the reaction [HSPA5 protein binds to FOS enhancer]; Mercury promotes the reaction [HSPA5 protein binds to HRAS enhancer]; Mercury results in increased expression of and results in increased activity of HSPA5 protein |
CTD |
PMID:15111246 |
|
NCBI chr 3:38,453,016...38,457,475
|
|
G |
Hspd1 |
heat shock protein family D (Hsp60) member 1 |
increases expression |
EXP |
Mercury results in increased expression of HSPD1 mRNA |
CTD |
PMID:12730625 |
|
NCBI chr 9:64,073,610...64,084,332
|
|
G |
Htr7 |
5-hydroxytryptamine receptor 7 |
increases expression |
ISO |
Mercury results in increased expression of HTR7 mRNA |
CTD |
PMID:16823088 |
|
NCBI chr 1:243,049,064...243,173,636
|
|
G |
Ifi44 |
interferon-induced protein 44 |
multiple interactions |
ISO |
[Mercuric Chloride results in increased abundance of Mercury] which results in increased expression of IFI44 mRNA |
CTD |
PMID:28453771 |
|
NCBI chr 2:243,286,050...243,303,869
|
|
G |
Ifng |
interferon gamma |
affects expression decreases secretion increases expression multiple interactions |
ISO |
Mercury affects the expression of IFNG mRNA; Mercury affects the expression of IFNG protein Mercury results in decreased secretion of IFNG protein Mercury results in increased expression of IFNG protein Mercury results in increased expression of IFNG mRNA [Mercuric Chloride results in increased abundance of Mercury] which results in increased expression of IFNG protein; IFNG gene mutant form inhibits the reaction [[Mercuric Chloride results in increased abundance of Mercury] which results in increased expression of FCGR1 mRNA]; IFNG gene mutant form inhibits the reaction [[Mercuric Chloride results in increased abundance of Mercury] which results in increased expression of IL4 mRNA]; IFNG gene mutant form inhibits the reaction [[Mercuric Chloride results in increased abundance of Mercury] which results in increased expression of IRF1 mRNA]; IFNG gene mutant form inhibits the reaction [[Mercuric Chloride results in increased abundance of Mercury] which results in increased expression of IRF8 mRNA]; IFNG gene mutant form inhibits the reaction [[Mercuric Chloride results in increased abundance of Mercury] which results in increased expression of TNF mRNA]; IL6 gene mutant form inhibits the reaction [[Mercuric Chloride results in increased abundance of Mercury] which results in increased expression of IFNG mRNA]; N-(3-propylcarbamoyloxirane-2-carbonyl)-isoleucyl-proline inhibits the reaction [Mercury results in increased expression of IFNG mRNA] |
CTD |
PMID:12928768 PMID:15910788 PMID:20176347 PMID:25237059 PMID:28453771 |
|
NCBI chr 7:55,789,180...55,793,216
|
|
G |
Ifngr1 |
interferon gamma receptor 1 |
affects response to substance |
ISO |
IFNGR1 affects the susceptibility to Mercury |
CTD |
PMID:22578563 |
|
NCBI chr 1:16,152,811...16,171,439
|
|
G |
Ifrd1 |
interferon-related developmental regulator 1 |
decreases expression |
ISO |
Mercury results in decreased expression of IFRD1 mRNA |
CTD |
PMID:17547211 |
|
NCBI chr 6:62,996,560...63,044,996
|
|
G |
Igf1 |
insulin-like growth factor 1 |
multiple interactions |
ISO |
Mercury inhibits the reaction [IGF1 protein results in increased activity of MTR protein] |
CTD |
PMID:14745455 |
|
NCBI chr 7:24,169,608...24,249,446
|
|
G |
Il10 |
interleukin 10 |
increases expression |
ISO |
Mercury results in increased expression of IL10 mRNA |
CTD |
PMID:16045731 |
|
NCBI chr13:45,024,921...45,029,586
|
|
G |
Il13 |
interleukin 13 |
increases expression |
ISO |
Mercury results in increased expression of IL13 mRNA |
CTD |
PMID:37137463 |
|
NCBI chr10:38,290,926...38,293,483
|
|
G |
Il17rb |
interleukin 17 receptor B |
decreases expression |
ISO |
Mercury results in decreased expression of IL17RB mRNA |
CTD |
PMID:17547211 |
|
NCBI chr16:5,186,961...5,200,657
|
|
G |
Il1b |
interleukin 1 beta |
increases expression multiple interactions |
ISO |
Mercury results in increased expression of IL1B protein Mercury promotes the reaction [Lipopolysaccharides results in increased secretion of IL1B protein] Mercury results in increased expression of IL1B mRNA; Mercury results in increased expression of IL1B protein [Mercuric Chloride results in increased abundance of Mercury] which results in increased expression of IL1B mRNA; N-(3-propylcarbamoyloxirane-2-carbonyl)-isoleucyl-proline inhibits the reaction [Mercury results in increased expression of IL1B mRNA] |
CTD |
PMID:20176347 PMID:20600710 PMID:25237059 PMID:28453771 PMID:37137463 |
|
NCBI chr 3:137,030,200...137,036,581
|
|
G |
Il2 |
interleukin 2 |
increases expression |
EXP |
Mercury results in increased expression of IL2 mRNA |
CTD |
PMID:12730625 |
|
NCBI chr 2:121,932,968...121,937,672
|
|
G |
Il33 |
interleukin 33 |
decreases expression |
ISO |
Mercury analog results in decreased expression of IL33 mRNA |
CTD |
PMID:25056781 |
|
NCBI chr 1:227,701,964...227,736,374
|
|
G |
Il3ra |
interleukin 3 receptor subunit alpha |
decreases expression |
ISO |
Mercury results in decreased expression of IL3RA mRNA |
CTD |
PMID:16823088 |
|
NCBI chr12:16,318,081...16,323,781
|
|
G |
Il4 |
interleukin 4 |
decreases secretion multiple interactions |
ISO |
Mercury results in decreased secretion of IL4 protein [Mercuric Chloride results in increased abundance of Mercury] which results in increased expression of IL4 mRNA; CASP1 gene mutant form inhibits the reaction [[Mercuric Chloride results in increased abundance of Mercury] which results in increased expression of IL4 mRNA]; IFNG gene mutant form inhibits the reaction [[Mercuric Chloride results in increased abundance of Mercury] which results in increased expression of IL4 mRNA]; IL6 gene mutant form inhibits the reaction [[Mercuric Chloride results in increased abundance of Mercury] which results in increased expression of IL4 mRNA] |
CTD |
PMID:15910788 PMID:28453771 |
|
NCBI chr10:38,272,003...38,277,549
|
|
G |
Il6 |
interleukin 6 |
increases expression multiple interactions |
ISO EXP |
Mercury results in increased expression of IL6 protein [Mercuric Chloride results in increased abundance of Mercury] which results in increased expression of IL6 mRNA; IL6 gene mutant form inhibits the reaction [[Mercuric Chloride results in increased abundance of Mercury] which results in increased expression of FCGR1 mRNA]; IL6 gene mutant form inhibits the reaction [[Mercuric Chloride results in increased abundance of Mercury] which results in increased expression of IFNG mRNA]; IL6 gene mutant form inhibits the reaction [[Mercuric Chloride results in increased abundance of Mercury] which results in increased expression of IL4 mRNA]; IL6 gene mutant form inhibits the reaction [[Mercuric Chloride results in increased abundance of Mercury] which results in increased expression of IRF1 mRNA]; IL6 gene mutant form inhibits the reaction [[Mercuric Chloride results in increased abundance of Mercury] which results in increased expression of IRF8 mRNA]; IL6 gene mutant form inhibits the reaction [[Mercuric Chloride results in increased abundance of Mercury] which results in increased expression of TNF mRNA]; Salicylic Acid inhibits the reaction [Mercury results in increased expression of IL6] [Aluminum co-treated with Lead co-treated with Mercury co-treated with Manganese] results in increased expression of IL6 protein; [Lead co-treated with Cadmium co-treated with Mercury co-treated with Arsenic] results in increased expression of IL6 protein; [Selenium co-treated with Zinc] inhibits the reaction [[Lead co-treated with Cadmium co-treated with Mercury co-treated with Arsenic] results in increased expression of IL6 protein]; Selenium inhibits the reaction [[Lead co-treated with Cadmium co-treated with Mercury co-treated with Arsenic] results in increased expression of IL6 protein]; Zinc inhibits the reaction [[Lead co-treated with Cadmium co-treated with Mercury co-treated with Arsenic] results in increased expression of IL6 protein] |
CTD |
PMID:18393961 PMID:23742082 PMID:28453771 PMID:37415728 PMID:37676925 |
|
NCBI chr 4:5,889,999...5,894,575
|
|
G |
Impg1 |
interphotoreceptor matrix proteoglycan 1 |
increases expression |
ISO |
Mercury results in increased expression of IMPG1 mRNA |
CTD |
PMID:16823088 |
|
NCBI chr 8:81,243,624...81,389,722
|
|
G |
Ins1 |
insulin 1 |
multiple interactions |
ISO |
[Mercuric Chloride results in increased abundance of Mercury] inhibits the reaction [Glucose results in increased secretion of INS1 protein] |
CTD |
PMID:33038468 |
|
NCBI chr 1:261,186,119...261,186,686
|
|
G |
Irf1 |
interferon regulatory factor 1 |
affects response to substance multiple interactions |
ISO |
IRF1 affects the susceptibility to Mercury [Mercuric Chloride results in increased abundance of Mercury] which results in increased expression of IRF1 mRNA; IFNG gene mutant form inhibits the reaction [[Mercuric Chloride results in increased abundance of Mercury] which results in increased expression of IRF1 mRNA]; IL6 gene mutant form inhibits the reaction [[Mercuric Chloride results in increased abundance of Mercury] which results in increased expression of IRF1 mRNA] |
CTD |
PMID:22578563 PMID:28453771 |
|
NCBI chr10:38,417,935...38,424,946
|
|
G |
Irf8 |
interferon regulatory factor 8 |
multiple interactions |
ISO |
[Mercuric Chloride results in increased abundance of Mercury] which results in increased expression of IRF8 mRNA; IFNG gene mutant form inhibits the reaction [[Mercuric Chloride results in increased abundance of Mercury] which results in increased expression of IRF8 mRNA]; IL6 gene mutant form inhibits the reaction [[Mercuric Chloride results in increased abundance of Mercury] which results in increased expression of IRF8 mRNA] |
CTD |
PMID:28453771 |
|
NCBI chr19:48,790,581...48,812,363
|
|
G |
Irs1 |
insulin receptor substrate 1 |
multiple interactions |
ISO |
[Cadmium co-treated with Mercury] results in increased phosphorylation of IRS1 protein |
CTD |
PMID:30629257 |
|
NCBI chr 9:91,001,137...91,053,959
|
|
G |
Isg15 |
ISG15 ubiquitin-like modifier |
decreases expression |
ISO |
Mercury analog results in decreased expression of ISG15 mRNA |
CTD |
PMID:25056781 |
|
NCBI chr 5:172,066,369...172,067,656
|
|
G |
Itgb1 |
integrin subunit beta 1 |
increases activity |
EXP |
Mercury results in increased activity of ITGB1 protein |
CTD |
PMID:10820171 |
|
NCBI chr19:73,602,277...73,650,271
|
|
G |
Itgb3bp |
integrin subunit beta 3 binding protein |
increases expression |
ISO |
Mercury results in increased expression of ITGB3BP mRNA |
CTD |
PMID:17547211 |
|
NCBI chr 5:114,460,217...114,525,538
|
|
G |
Itih1 |
inter-alpha trypsin inhibitor, heavy chain 1 |
affects expression |
ISO |
Mercury affects the expression of ITIH1 protein |
CTD |
PMID:22030286 |
|
NCBI chr16:6,122,246...6,136,363
|
|
G |
Itih3 |
inter-alpha trypsin inhibitor, heavy chain 3 |
decreases expression |
ISO |
Mercury results in decreased expression of ITIH3 mRNA |
CTD |
PMID:17547211 |
|
NCBI chr16:6,101,922...6,117,154
|
|
G |
Itih4 |
inter-alpha-trypsin inhibitor heavy chain 4 |
affects expression |
ISO |
Mercury affects the expression of ITIH4 protein |
CTD |
PMID:22030286 |
|
NCBI chr16:6,080,539...6,095,710
|
|
G |
Ivns1abp |
influenza virus NS1A binding protein |
decreases expression |
ISO |
Mercury results in decreased expression of IVNS1ABP mRNA |
CTD |
PMID:16823088 |
|
NCBI chr13:65,977,069...65,996,685
|
|
G |
Jak2 |
Janus kinase 2 |
affects expression |
ISO |
Mercury affects the expression of JAK2 mRNA |
CTD |
PMID:23920476 |
|
NCBI chr 1:236,408,905...236,468,769
|
|
G |
Jun |
Jun proto-oncogene, AP-1 transcription factor subunit |
decreases expression multiple interactions |
EXP ISO |
Mercury results in decreased expression of JUN mRNA [Copper co-treated with Lead co-treated with Cadmium co-treated with Zinc co-treated with Mercury co-treated with Chromium co-treated with Manganese co-treated with Nickel] results in increased expression of JUN protein |
CTD |
PMID:12730625 PMID:28035397 |
|
NCBI chr 5:115,009,900...115,012,993
|
|
G |
Kcnh2 |
potassium voltage-gated channel subfamily H member 2 |
increases expression |
ISO |
Mercury results in increased expression of KCNH2 mRNA |
CTD |
PMID:16823088 |
|
NCBI chr 4:11,719,357...11,751,424
|
|
G |
Kdelr2 |
KDEL endoplasmic reticulum protein retention receptor 2 |
decreases expression |
ISO |
Mercury analog results in decreased expression of KDELR2 mRNA |
CTD |
PMID:25056781 |
|
NCBI chr12:11,138,820...11,157,117
|
|
G |
Klf12 |
KLF transcription factor 12 |
decreases expression |
ISO |
Mercury results in decreased expression of KLF12 mRNA |
CTD |
PMID:19937285 |
|
NCBI chr15:83,037,548...83,469,998
|
|
G |
Klf2 |
KLF transcription factor 2 |
decreases expression |
ISO |
Mercury results in decreased expression of KLF2 mRNA |
CTD |
PMID:19937285 |
|
NCBI chr16:17,521,107...17,523,739
|
|
G |
Kmt2b |
lysine methyltransferase 2B |
increases expression |
ISO |
Mercury results in increased expression of KMT2B mRNA |
CTD |
PMID:16823088 |
|
NCBI chr 1:85,821,700...85,840,987
|
|
G |
Krt1 |
keratin 1 |
increases expression |
ISO |
Mercury results in increased expression of KRT1 mRNA |
CTD |
PMID:19937285 |
|
NCBI chr 7:132,976,618...132,981,844
|
|
G |
Lamc1 |
laminin subunit gamma 1 |
decreases expression |
ISO |
Mercury analog results in decreased expression of LAMC1 mRNA |
CTD |
PMID:25056781 |
|
NCBI chr13:67,924,872...68,051,986
|
|
G |
Lancl1 |
LanC like glutathione S-transferase 1 |
decreases expression |
ISO |
Mercury results in decreased expression of LANCL1 mRNA |
CTD |
PMID:16823088 |
|
NCBI chr 9:68,515,052...68,548,646
|
|
G |
Lancl2 |
LanC like glutathione S-transferase 2 |
decreases expression |
ISO |
Mercury results in decreased expression of LANCL2 mRNA |
CTD |
PMID:19937285 |
|
NCBI chr 4:87,441,821...87,483,707
|
|
G |
Lcn2 |
lipocalin 2 |
increases expression |
EXP |
Mercury results in increased expression of LCN2 mRNA |
CTD |
PMID:25145654 |
|
NCBI chr 3:36,078,432...36,081,851
|
|
G |
Leng9 |
leukocyte receptor cluster member 9 |
decreases expression |
ISO |
Mercury analog results in decreased expression of LENG9 mRNA |
CTD |
PMID:25056781 |
|
NCBI chr 1:70,039,099...70,041,559
|
|
G |
Lepr |
leptin receptor |
decreases expression |
ISO |
Mercury results in decreased expression of LEPR mRNA |
CTD |
PMID:16823088 |
|
NCBI chr 5:121,409,735...121,593,201
|
|
G |
Limd1 |
LIM domain containing 1 |
decreases expression |
ISO |
Mercury analog results in decreased expression of LIMD1 mRNA |
CTD |
PMID:25056781 |
|
NCBI chr 8:123,121,363...123,168,476
|
|
G |
Lims2 |
LIM zinc finger domain containing 2 |
decreases expression |
ISO |
Mercury analog results in decreased expression of LIMS2 mRNA |
CTD |
PMID:25056781 |
|
NCBI chr18:23,553,937...23,592,137
|
|
G |
Lipa |
lipase A, lysosomal acid type |
decreases expression |
ISO |
Mercury results in decreased expression of LIPA mRNA |
CTD |
PMID:17547211 |
|
NCBI chr 1:241,437,524...241,470,936
|
|
G |
Lmbr1 |
limb development membrane protein 1 |
decreases expression |
ISO |
Mercury analog results in decreased expression of LMBR1 mRNA |
CTD |
PMID:25056781 |
|
NCBI chr 4:5,974,687...6,146,348
|
|
G |
Lmna |
lamin A/C |
decreases expression |
ISO |
Mercury results in decreased expression of LMNA mRNA |
CTD |
PMID:16823088 |
|
NCBI chr 2:176,237,564...176,265,301
|
|
G |
Lrrfip1 |
LRR binding FLII interacting protein 1 |
increases expression |
ISO |
Mercury results in increased expression of LRRFIP1 mRNA |
CTD |
PMID:16823088 |
|
NCBI chr 9:99,039,590...99,167,805
|
|
G |
Lsm5 |
LSM5 homolog, U6 small nuclear RNA and mRNA degradation associated |
decreases expression |
ISO |
Mercury analog results in decreased expression of LSM5 mRNA |
CTD |
PMID:25056781 |
|
NCBI chr 4:85,951,073...85,954,289
|
|
G |
Ltf |
lactotransferrin |
increases expression |
ISO |
Mercury results in increased expression of LTF protein |
CTD |
PMID:37137463 |
|
NCBI chr 8:110,999,948...111,022,795
|
|
G |
Lyn |
LYN proto-oncogene, Src family tyrosine kinase |
multiple interactions |
ISO |
Mercury results in increased phosphorylation of and results in increased activity of LYN protein |
CTD |
PMID:24440445 |
|
NCBI chr 5:21,437,127...21,553,097
|
|
G |
Lzts2 |
leucine zipper tumor suppressor 2 |
decreases expression |
ISO |
Mercury analog results in decreased expression of LZTS2 mRNA |
CTD |
PMID:25056781 |
|
NCBI chr 1:253,824,073...253,837,614
|
|
G |
Macf1 |
microtubule-actin crosslinking factor 1 |
increases expression |
ISO |
Mercury results in increased expression of MACF1 mRNA |
CTD |
PMID:16823088 |
|
NCBI chr 5:140,908,829...141,234,127
|
|
G |
Maff |
MAF bZIP transcription factor F |
increases expression |
ISO |
Mercury results in increased expression of MAFF mRNA |
CTD |
PMID:19937285 |
|
NCBI chr 7:112,792,787...112,804,139
|
|
G |
Mageb1 |
MAGE family member B1 |
increases expression |
ISO |
Mercury results in increased expression of MAGEB4 mRNA |
CTD |
PMID:16823088 |
|
NCBI chr X:50,915,789...50,921,863
|
|
G |
Man1b1 |
mannosidase, alpha, class 1B, member 1 |
affects expression |
ISO |
Mercury affects the expression of MAN1B1 mRNA |
CTD |
PMID:23920476 |
|
NCBI chr 3:28,539,778...28,563,155
|
|
G |
Map2 |
microtubule-associated protein 2 |
multiple interactions |
ISO |
[diethyl phosphate co-treated with Cotinine co-treated with bis(2,3,3,3-tetrachloropropyl) ether co-treated with Mercury co-treated with Selenium] results in increased expression of MAP2 mRNA |
CTD |
PMID:37914285 |
|
NCBI chr 9:75,173,038...75,431,606
|
|
G |
Map2k2 |
mitogen activated protein kinase kinase 2 |
increases expression |
ISO |
Mercury results in increased expression of MAP2K2 mRNA |
CTD |
PMID:16823088 |
|
NCBI chr 7:9,241,449...9,264,216
|
|
G |
Map9 |
microtubule-associated protein 9 |
increases expression |
ISO |
Mercury results in increased expression of MAP9 mRNA |
CTD |
PMID:19937285 |
|
NCBI chr 2:167,708,661...167,743,927
|
|
G |
Mapk1 |
mitogen activated protein kinase 1 |
increases phosphorylation |
ISO |
Mercury results in increased phosphorylation of MAPK1 protein |
CTD |
PMID:21994240 |
|
NCBI chr11:97,462,025...97,529,193
|
|
G |
Mapk3 |
mitogen activated protein kinase 3 |
increases phosphorylation |
ISO |
Mercury results in increased phosphorylation of MAPK3 protein |
CTD |
PMID:21994240 |
|
NCBI chr 1:190,797,189...190,803,411
|
|
G |
Mcm2 |
minichromosome maintenance complex component 2 |
increases expression |
ISO |
Mercury results in increased expression of MCM2 mRNA |
CTD |
PMID:17547211 |
|
NCBI chr 4:122,903,679...122,918,205
|
|
G |
Med16 |
mediator complex subunit 16 |
increases expression |
ISO |
Mercury results in increased expression of MED16 mRNA |
CTD |
PMID:16823088 |
|
NCBI chr 7:9,798,641...9,811,172
|
|
G |
Meox2 |
mesenchyme homeobox 2 |
increases expression |
ISO |
Mercury results in increased expression of MEOX2 mRNA |
CTD |
PMID:16823088 |
|
NCBI chr 6:53,856,760...53,917,467
|
|
G |
Mfap5 |
microfibril associated protein 5 |
increases expression |
ISO |
Mercury results in increased expression of MFAP5 mRNA |
CTD |
PMID:16823088 |
|
NCBI chr 4:155,727,925...155,750,458
|
|
G |
Mgat2 |
alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase |
decreases expression |
ISO |
Mercury results in decreased expression of MGAT2 mRNA |
CTD |
PMID:17547211 |
|
NCBI chr 6:87,656,360...87,658,849
|
|
G |
Mgat5 |
alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase |
increases expression |
EXP |
Mercury results in increased expression of MGAT5 mRNA |
CTD |
PMID:22688007 |
|
NCBI chr13:38,675,776...38,959,697
|
|
G |
Mir10a |
microRNA 10a |
decreases expression |
ISO |
Mercury results in decreased expression of MIR10A mRNA |
CTD |
PMID:26252056 |
|
NCBI chr10:81,283,171...81,283,280
|
|
G |
Mir151 |
microRNA 151 |
decreases expression |
ISO |
Mercury results in decreased expression of MIR151A mRNA |
CTD |
PMID:26252056 |
|
NCBI chr 7:105,172,377...105,172,473
|
|
G |
Mir190b |
microRNA 190b |
decreases expression |
ISO |
Mercury results in decreased expression of MIR190B mRNA |
CTD |
PMID:26252056 |
|
NCBI chr 2:175,514,800...175,514,877
|
|
G |
Mir193b |
microRNA 193b |
decreases expression |
ISO |
Mercury results in decreased expression of MIR193B mRNA |
CTD |
PMID:26252056 |
|
NCBI chr10:1,317,742...1,317,824
|
|
G |
Mir423 |
microRNA 423 |
decreases expression |
ISO |
Mercury results in decreased expression of MIR423 mRNA |
CTD |
PMID:26252056 |
|
NCBI chr10:61,914,142...61,914,220
|
|
G |
Mir96 |
microRNA 96 |
decreases expression |
ISO |
Mercury results in decreased expression of MIR96 mRNA |
CTD |
PMID:26252056 |
|
NCBI chr 4:58,788,411...58,788,516
|
|
G |
Mirlet7b |
microRNA let-7b |
decreases expression |
ISO |
Mercury results in decreased expression of MIRLET7B mRNA |
CTD |
PMID:26252056 |
|
NCBI chr 7:116,804,186...116,804,270
|
|
G |
Mirlet7c1 |
microRNA let-7c-1 |
decreases expression |
ISO |
Mercury results in decreased expression of MIRLET7C mRNA |
CTD |
PMID:26252056 |
|
NCBI chr11:16,201,163...16,201,256
|
|
G |
Mirlet7d |
microRNA let-7d |
decreases expression |
ISO |
Mercury results in decreased expression of MIRLET7D mRNA |
CTD |
PMID:26252056 |
|
NCBI chr17:16,115,893...16,115,990
|
|
G |
Mirlet7g |
microRNA let-7g |
decreases expression |
ISO |
Mercury results in decreased expression of MIRLET7G mRNA |
CTD |
PMID:26252056 |
|
NCBI chr 8:106,822,293...106,822,380
|
|
G |
Mirlet7i |
microRNA let-7i |
decreases expression |
ISO |
Mercury results in decreased expression of MIRLET7I mRNA |
CTD |
PMID:26252056 |
|
NCBI chr 7:58,642,485...58,642,569
|
|
G |
Mme |
membrane metallo-endopeptidase |
increases expression multiple interactions |
ISO |
Mercury results in increased expression of MME protein Mercury affects the folding of and results in decreased activity of MME protein |
CTD |
PMID:25673500 |
|
NCBI chr 2:149,806,826...149,957,381
|
|
G |
Mmp2 |
matrix metallopeptidase 2 |
multiple interactions |
ISO |
Mercury affects the reaction [MMP2 promoter polymorphism results in increased expression of MMP2 protein] |
CTD |
PMID:21794897 |
|
NCBI chr19:30,327,643...30,355,856
|
|
G |
Mmp9 |
matrix metallopeptidase 9 |
affects response to substance |
ISO |
MMP9 promoter polymorphism affects the susceptibility to Mercury |
CTD |
PMID:20554312 |
|
NCBI chr 3:174,103,474...174,111,434
|
|
G |
Morf4l2 |
mortality factor 4 like 2 |
decreases expression |
ISO |
Mercury results in decreased expression of MORF4L2 mRNA |
CTD |
PMID:16823088 |
|
NCBI chr X:104,874,850...104,885,946
|
|
G |
Mpo |
myeloperoxidase |
decreases activity |
ISO |
Mercury results in decreased activity of MPO protein |
CTD |
PMID:15557676 |
|
NCBI chr10:73,092,124...73,102,057
|
|
G |
Mrps23 |
mitochondrial ribosomal protein S23 |
decreases expression |
ISO |
Mercury analog results in decreased expression of MRPS23 mRNA |
CTD |
PMID:25056781 |
|
NCBI chr10:73,494,417...73,503,996
|
|
G |
Msh6 |
mutS homolog 6 |
increases expression |
ISO |
Mercury results in increased expression of MSH6 mRNA |
CTD |
PMID:19937285 |
|
NCBI chr 6:12,316,190...12,333,505
|
|
G |
Msl3 |
MSL complex subunit 3 |
decreases expression |
ISO |
Mercury analog results in decreased expression of MSL3 mRNA |
CTD |
PMID:25056781 |
|
NCBI chr X:25,638,029...25,655,698
|
|
G |
Msr1 |
macrophage scavenger receptor 1 |
multiple interactions |
ISO |
[Mercuric Chloride results in increased abundance of Mercury] which results in increased expression of MSR1 mRNA |
CTD |
PMID:28453771 |
|
NCBI chr16:52,717,775...52,803,602
|
|
G |
Mt1 |
metallothionein 1 |
increases expression affects abundance multiple interactions affects binding increases response to substance |
EXP ISO |
Mercury results in increased expression of MT1 mRNA; Mercury results in increased expression of MT1 protein; Mercury results in increased expression of MT1A mRNA MT1A gene polymorphism affects the abundance of Mercury; MT1A gene SNP affects the abundance of Mercury [MT1 co-treated with MT2] affects the susceptibility to Mercury Mercury binds to MT1 protein MT1 gene mutant form results in increased susceptibility to Mercury |
CTD |
PMID:8917669 PMID:9462895 PMID:9587011 PMID:12167210 PMID:12730625 PMID:15138662 PMID:15603537 PMID:15782327 PMID:17018868 PMID:19515364 PMID:21628964 PMID:22008530 PMID:22233731 More...
|
|
NCBI chr19:10,831,959...10,832,975
|
|
G |
Mt1-ps3 |
metallothionein 1, pseudogene 3 |
affects response to substance |
ISO |
MT1E gene SNP affects the susceptibility to Mercury |
CTD |
PMID:22236634 |
|
NCBI chr17:79,695,812...79,696,200
|
|
G |
Mt2A |
metallothionein 2A |
affects abundance affects binding increases expression increases response to substance multiple interactions affects response to substance |
ISO EXP |
MT2A gene SNP affects the abundance of Mercury Mercury binds to MT2 protein Mercury results in increased expression of MT2 mRNA; Mercury results in increased expression of MT2 protein MT2 gene mutant form results in increased susceptibility to Mercury [MT1 co-treated with MT2] affects the susceptibility to Mercury; [MT3 protein affects the susceptibility to Mercury] which affects the expression of MT2 mRNA [MT1M gene polymorphism co-treated with MT2A gene polymorphism] affects the susceptibility to Mercury MT2A gene polymorphism affects the susceptibility to Mercury Mercury results in increased expression of MT2A mRNA |
CTD |
PMID:2771874 PMID:8917669 PMID:9462895 PMID:9587011 PMID:15138662 PMID:15603537 PMID:15782327 PMID:17018868 PMID:21628964 PMID:22008530 PMID:22233731 PMID:23827881 PMID:30103553 More...
|
|
NCBI chr19:10,837,934...10,838,708
|
|
G |
Mt3 |
metallothionein 3 |
affects binding increases expression multiple interactions affects response to substance |
ISO EXP |
Mercury binds to MT3 protein Mercury results in increased expression of MT3 mRNA; Mercury results in increased expression of MT3 protein [MT3 protein affects the susceptibility to Mercury] which affects the expression of CCL7 mRNA; [MT3 protein affects the susceptibility to Mercury] which affects the expression of MT2 mRNA; MT3 protein affects the reaction [Mercury results in increased expression of CCL3 mRNA] |
CTD |
PMID:8917669 PMID:9587011 PMID:15138662 PMID:15782327 PMID:17018868 PMID:30103553 More...
|
|
NCBI chr19:10,848,754...10,850,158
|
|
G |
Mt4 |
metallothionein 4 |
affects abundance |
ISO |
MT4 gene polymorphism affects the abundance of Mercury |
CTD |
PMID:19515364 |
|
NCBI chr19:10,863,813...10,865,909
|
|
G |
Mtf1 |
metal-regulatory transcription factor 1 |
increases expression |
ISO |
Mercury results in increased expression of MTF1 mRNA |
CTD |
PMID:16823088 |
|
NCBI chr 5:137,062,319...137,107,136
|
|
G |
Mtmr11 |
myotubularin related protein 11 |
decreases expression |
ISO |
Mercury results in decreased expression of MTMR11 mRNA |
CTD |
PMID:16823088 |
|
NCBI chr 2:183,721,983...183,732,148
|
|
G |
Mtr |
5-methyltetrahydrofolate-homocysteine methyltransferase |
multiple interactions |
ISO |
Mercury inhibits the reaction [[Hydroxocobalamin co-treated with S-Adenosylmethionine] results in increased activity of MTR protein alternative form]; Mercury inhibits the reaction [IGF1 protein results in increased activity of MTR protein]; Mercury inhibits the reaction [mecobalamin results in increased activity of MTR protein alternative form] |
CTD |
PMID:14745455 PMID:26989453 |
|
NCBI chr17:62,911,705...62,996,544
|
|
G |
Mtrf1 |
mitochondrial translation release factor 1 |
decreases expression |
ISO |
Mercury results in decreased expression of MTRF1 mRNA |
CTD |
PMID:19937285 |
|
NCBI chr15:54,776,885...54,804,699
|
|
G |
Muc2 |
mucin 2, oligomeric mucus/gel-forming |
increases expression |
ISO |
Mercury results in increased expression of MUC2 mRNA |
CTD |
PMID:37137463 |
|
NCBI chr 1:206,225,775...206,261,280
|
|
G |
Mvb12b |
multivesicular body subunit 12B |
increases expression |
ISO |
Mercury results in increased expression of MVB12B mRNA |
CTD |
PMID:16823088 |
|
NCBI chr 3:17,034,002...17,192,658
|
|
G |
Myc |
MYC proto-oncogene, bHLH transcription factor |
decreases expression affects expression |
ISO |
Mercury results in decreased expression of MYC mRNA Mercury affects the expression of MYC mRNA |
CTD |
PMID:12928768 PMID:16823088 |
|
NCBI chr 7:95,483,105...95,488,031
|
|
G |
Myo1b |
myosin Ib |
increases expression decreases expression |
ISO |
Mercury results in increased expression of MYO1B mRNA Mercury analog results in decreased expression of MYO1B mRNA |
CTD |
PMID:16823088 PMID:25056781 |
|
NCBI chr 9:49,690,043...49,852,373
|
|
G |
Mzf1 |
myeloid zinc finger 1 |
decreases expression |
ISO |
Mercury analog results in decreased expression of MZF1 mRNA |
CTD |
PMID:25056781 |
|
NCBI chr 1:73,670,522...73,682,885
|
|
G |
Nap1l1 |
nucleosome assembly protein 1-like 1 |
increases expression |
ISO |
Mercury results in increased expression of NAP1L1 mRNA |
CTD |
PMID:16823088 |
|
NCBI chr 7:48,819,464...48,844,108
|
|
G |
Nat1 |
N-acetyltransferase 1 |
multiple interactions |
ISO |
Mercury binds to and results in decreased activity of NAT1 protein |
CTD |
PMID:20591428 |
|
NCBI chr16:22,218,217...22,238,516
|
|
G |
Nav3 |
neuron navigator 3 |
increases expression |
ISO |
Mercury results in increased expression of NAV3 mRNA |
CTD |
PMID:16823088 |
|
NCBI chr 7:46,938,577...47,726,839
|
|
G |
Ncapd3 |
non-SMC condensin II complex, subunit D3 |
increases expression decreases expression |
ISO |
Mercury results in increased expression of NCAPD3 mRNA Mercury analog results in decreased expression of NCAPD3 mRNA |
CTD |
PMID:19937285 PMID:25056781 |
|
NCBI chr 8:25,437,067...25,506,375
|
|
G |
Ncoa3 |
nuclear receptor coactivator 3 |
increases expression |
ISO |
Mercury results in increased expression of NCOA3 mRNA |
CTD |
PMID:16823088 |
|
NCBI chr 3:175,157,824...175,237,831
|
|
G |
Ndufs2 |
NADH:ubiquinone oxidoreductase core subunit S2 |
decreases expression |
ISO |
Mercury results in decreased expression of NDUFS2 mRNA |
CTD |
PMID:16823088 |
|
NCBI chr13:83,654,402...83,671,474
|
|
G |
Nfatc4 |
nuclear factor of activated T-cells 4 |
increases expression |
ISO |
Mercury results in increased expression of NFATC4 mRNA |
CTD |
PMID:19937285 |
|
NCBI chr15:33,256,912...33,284,522
|
|
G |
Nfe2l2 |
NFE2 like bZIP transcription factor 2 |
multiple interactions increases expression increases activity |
ISO EXP |
NFE2L2 protein affects the reaction [Mercury results in increased expression of GSTA1 mRNA]; NFE2L2 protein affects the reaction [Mercury results in increased expression of NQO1 mRNA] Mercury results in increased expression of NFE2L2 mRNA Mercury results in increased activity of NFE2L2 promoter [Mercuric Chloride results in increased abundance of Mercury] which results in decreased expression of NFE2L2 protein [Aluminum co-treated with Lead co-treated with Mercury co-treated with Manganese co-treated with Selenium] results in decreased expression of NFE2L2 protein; [Aluminum co-treated with Lead co-treated with Mercury co-treated with Manganese co-treated with Zinc] results in decreased expression of NFE2L2 protein; [Aluminum co-treated with Lead co-treated with Mercury co-treated with Manganese] results in decreased expression of NFE2L2 protein; [Mercuric Chloride results in increased abundance of Mercury] which results in increased expression of NFE2L2 mRNA; [Mercuric Chloride results in increased abundance of Mercury] which results in increased expression of NFE2L2 protein; Curcumin promotes the reaction [[Mercuric Chloride results in increased abundance of Mercury] which results in increased expression of NFE2L2 mRNA]; Curcumin promotes the reaction [[Mercuric Chloride results in increased abundance of Mercury] which results in increased expression of NFE2L2 protein] |
CTD |
PMID:16243960 PMID:21643505 PMID:27837179 PMID:30359721 PMID:37415728 |
|
NCBI chr 3:81,001,529...81,031,165
|
|
G |
Nfkb1 |
nuclear factor kappa B subunit 1 |
multiple interactions |
ISO EXP |
Mercury inhibits the reaction [lipopolysaccharide, E. coli O26-B6 results in increased activity of NFKB1 protein] [Aluminum co-treated with Lead co-treated with Mercury co-treated with Manganese co-treated with Zinc] results in decreased expression of NFKB1 protein; [Aluminum co-treated with Lead co-treated with Mercury co-treated with Manganese] results in decreased expression of NFKB1 protein; Mercury inhibits the reaction [Lipopolysaccharides results in increased activity of [RELA protein binds to NFKB1 protein]]; Mercury inhibits the reaction [TNF protein results in increased activity of [RELA protein binds to NFKB1 protein]] |
CTD |
PMID:11437639 PMID:15282405 PMID:37415728 |
|
NCBI chr 2:226,689,745...226,805,897
|
|
G |
Nfkbia |
NFKB inhibitor alpha |
multiple interactions |
ISO |
Mercury inhibits the reaction [lipopolysaccharide, E. coli O26-B6 results in increased phosphorylation of and results in increased degradation of NFKBIA protein] |
CTD |
PMID:11437639 |
|
NCBI chr 6:78,593,844...78,597,307
|
|
G |
Ngf |
nerve growth factor |
increases expression decreases expression |
ISO EXP |
Mercury results in increased expression of NGF mRNA Mercury results in decreased expression of NGF mRNA |
CTD |
PMID:7781173 PMID:16823088 |
|
NCBI chr 2:192,589,580...192,642,971
|
|
G |
Ngfr |
nerve growth factor receptor |
decreases expression |
EXP |
Mercury results in decreased expression of NGFR mRNA |
CTD |
PMID:7781173 |
|
NCBI chr10:81,012,077...81,030,305
|
|
G |
Nherf2 |
NHERF family PDZ scaffold protein 2 |
increases expression |
ISO |
Mercury results in increased expression of NHERF2 mRNA |
CTD |
PMID:16823088 |
|
NCBI chr10:13,662,461...13,672,975
|
|
G |
Nlrp1a |
NLR family, pyrin domain containing 1A |
decreases expression |
ISO |
Mercury results in decreased expression of NLRP1 mRNA |
CTD |
PMID:19937285 |
|
NCBI chr10:55,778,560...55,833,639
|
|
G |
Nlrp3 |
NLR family, pyrin domain containing 3 |
increases expression multiple interactions |
ISO |
Mercury results in increased expression of NLRP3 mRNA N-(3-propylcarbamoyloxirane-2-carbonyl)-isoleucyl-proline inhibits the reaction [Mercury results in increased expression of NLRP3 mRNA] |
CTD |
PMID:25237059 |
|
NCBI chr10:44,826,299...44,853,373
|
|
G |
Nmt2 |
N-myristoyltransferase 2 |
increases expression |
ISO |
Mercury results in increased expression of NMT2 mRNA |
CTD |
PMID:16823088 |
|
NCBI chr17:74,917,833...74,964,788
|
|
G |
Nod1 |
nucleotide-binding oligomerization domain containing 1 |
decreases expression |
ISO |
Mercury results in decreased expression of NOD1 mRNA |
CTD |
PMID:19937285 |
|
NCBI chr 4:85,391,142...85,442,281
|
|
G |
Nox4 |
NADPH oxidase 4 |
multiple interactions |
ISO |
[Mercuric Chloride results in increased abundance of Mercury] which results in increased expression of NOX4 protein |
CTD |
PMID:30359721 |
|
NCBI chr 1:150,313,736...150,491,480
|
|
G |
Nqo1 |
NAD(P)H quinone dehydrogenase 1 |
multiple interactions increases activity increases expression |
ISO |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Cycloheximide inhibits the reaction [Mercury results in increased expression of NQO1 mRNA]]; Buthionine Sulfoximine promotes the reaction [Mercury results in increased expression of NQO1 mRNA]; Buthionine Sulfoximine promotes the reaction [Mercury results in increased expression of NQO1 protein]; Cycloheximide inhibits the reaction [Mercury results in increased expression of NQO1 mRNA]; Dactinomycin inhibits the reaction [Mercury results in increased expression of NQO1 mRNA]; Mercury promotes the reaction [Tetrachlorodibenzodioxin results in increased activity of NQO1 protein]; Mercury promotes the reaction [Tetrachlorodibenzodioxin results in increased expression of NQO1 mRNA]; Mercury promotes the reaction [Tetrachlorodibenzodioxin results in increased expression of NQO1 protein]; Mercury results in increased expression of and results in increased activity of NQO1 protein; NFE2L2 protein affects the reaction [Mercury results in increased expression of NQO1 mRNA]; prolinedithiocarbamate promotes the reaction [Mercury results in increased expression of NQO1 protein]; pyrazolanthrone inhibits the reaction [Mercury results in increased expression of NQO1 mRNA]; pyrazolanthrone inhibits the reaction [Mercury results in increased expression of NQO1 protein]; Tetradecanoylphorbol Acetate inhibits the reaction [Mercury results in increased expression of NQO1 mRNA]; Tetradecanoylphorbol Acetate inhibits the reaction [Mercury results in increased expression of NQO1 protein]; U 0126 promotes the reaction [Mercury results in increased expression of NQO1 mRNA]; U 0126 promotes the reaction [Mercury results in increased expression of NQO1 protein] Mercury results in increased activity of NQO1 protein Mercury results in increased expression of NQO1 mRNA; Mercury results in increased expression of NQO1 protein Acetylcysteine inhibits the reaction [Mercury results in increased expression of NQO1 mRNA] |
CTD |
PMID:16243960 PMID:18752316 PMID:22579925 PMID:26600472 |
|
NCBI chr19:52,205,374...52,220,267
|
|
G |
Nr4a1 |
nuclear receptor subfamily 4, group A, member 1 |
decreases expression |
EXP |
Mercury results in decreased expression of NR4A1 mRNA |
CTD |
PMID:12730625 |
|
NCBI chr 7:132,368,399...132,389,300
|
|
G |
Nsrp1 |
nuclear speckle splicing regulatory protein 1 |
decreases expression |
ISO |
Mercury analog results in decreased expression of NSRP1 mRNA |
CTD |
PMID:25056781 |
|
NCBI chr10:61,880,807...61,914,471
|
|
G |
Ntrk3 |
neurotrophic receptor tyrosine kinase 3 |
increases expression |
ISO |
Mercury results in increased expression of NTRK3 mRNA |
CTD |
PMID:19937285 |
|
NCBI chr 1:141,526,192...141,913,575
|
|
G |
Nup107 |
nucleoporin 107 |
increases expression |
ISO |
Mercury results in increased expression of NUP107 mRNA |
CTD |
PMID:17547211 |
|
NCBI chr 7:53,353,740...53,398,345
|
|
G |
Ocln |
occludin |
decreases expression |
ISO |
Mercury results in decreased expression of OCLN mRNA |
CTD |
PMID:37137463 |
|
NCBI chr 2:33,391,303...33,442,207
|
|
G |
Ogg1 |
8-oxoguanine DNA glycosylase |
decreases expression |
ISO |
Mercury results in decreased expression of OGG1 mRNA |
CTD |
PMID:22641096 |
|
NCBI chr 4:148,030,237...148,037,599
|
|
G |
Oprd1 |
opioid receptor, delta 1 |
multiple interactions |
EXP |
Mercury inhibits the reaction [enkephalin, Ser(2), Leu(5), Thr(6)- binds to OPRD1 protein] |
CTD |
PMID:2162496 |
|
NCBI chr 5:149,590,244...149,624,999
|
|
G |
Oprk1 |
opioid receptor, kappa 1 |
multiple interactions |
EXP |
Mercury inhibits the reaction [Ethylketocyclazocine binds to OPRK1 protein] |
CTD |
PMID:2162496 |
|
NCBI chr 5:18,657,866...18,675,671
|
|
G |
Oprm1 |
opioid receptor, mu 1 |
multiple interactions |
EXP |
Mercury inhibits the reaction [Enkephalin, Ala(2)-MePhe(4)-Gly(5)- binds to OPRM1 protein] |
CTD |
PMID:2162496 |
|
NCBI chr 1:45,565,371...45,818,722
|
|
G |
Os9 |
OS9, endoplasmic reticulum lectin |
decreases expression |
ISO |
Mercury results in decreased expression of OS9 mRNA |
CTD |
PMID:17547211 |
|
NCBI chr 7:62,915,498...62,957,591
|
|
G |
P2rx2 |
purinergic receptor P2X 2 |
multiple interactions |
EXP |
Mercury promotes the reaction [Adenosine Triphosphate results in increased activity of P2RX2 protein]; methyl methanethiosulfonate inhibits the reaction [Mercury promotes the reaction [Adenosine Triphosphate results in increased activity of P2RX2 protein]] |
CTD |
PMID:19793987 |
|
NCBI chr12:46,338,979...46,342,891
|
|
G |
P2rx4 |
purinergic receptor P2X 4 |
multiple interactions |
EXP |
[Mercury co-treated with Copper] inhibits the reaction [Adenosine Triphosphate results in increased activity of P2RX4 protein]; Mercury inhibits the reaction [Adenosine Triphosphate results in increased activity of P2RX4 protein] |
CTD |
PMID:10737610 PMID:15629187 PMID:19793987 |
|
NCBI chr12:33,844,609...33,862,265
|
|
G |
Park7 |
Parkinsonism associated deglycase |
increases expression affects binding |
ISO |
Mercury results in increased expression of PARK7 mRNA Mercury binds to PARK7 protein |
CTD |
PMID:16823088 PMID:23792957 |
|
NCBI chr 5:166,636,551...166,659,825
|
|
G |
Parp1 |
poly (ADP-ribose) polymerase 1 |
multiple interactions |
ISO |
[Lead co-treated with Cadmium co-treated with Mercury co-treated with Copper co-treated with Zinc co-treated with Manganese co-treated with Chromium co-treated with Nickel] results in increased cleavage of PARP1 protein; Luteolin inhibits the reaction [[Lead co-treated with Cadmium co-treated with Mercury co-treated with Copper co-treated with Zinc co-treated with Manganese co-treated with Chromium co-treated with Nickel] results in increased cleavage of PARP1 protein] |
CTD |
PMID:29115570 |
|
NCBI chr13:94,839,484...94,871,295
|
|
G |
Pax6 |
paired box 6 |
multiple interactions |
ISO |
[diethyl phosphate co-treated with Cotinine co-treated with bis(2,3,3,3-tetrachloropropyl) ether co-treated with Mercury co-treated with Selenium] results in increased expression of PAX6 mRNA |
CTD |
PMID:37914285 |
|
NCBI chr 3:92,128,772...92,157,022
|
|
G |
Pcdhb5 |
protocadherin beta 5 |
decreases expression |
ISO |
Mercury results in decreased expression of PCDHB4 mRNA |
CTD |
PMID:22008530 |
|
NCBI chr18:29,024,315...29,032,183
|
|
G |
Pde1a |
phosphodiesterase 1A |
decreases expression |
ISO |
Mercury results in decreased expression of PDE1A mRNA |
CTD |
PMID:22008530 |
|
NCBI chr 3:64,745,140...65,025,178
|
|
G |
Pde4dip |
phosphodiesterase 4D interacting protein |
increases expression |
ISO |
Mercury results in increased expression of PDE4DIP mRNA |
CTD |
PMID:16823088 |
|
NCBI chr 2:185,293,236...185,490,100
|
|
G |
Pdia4 |
protein disulfide isomerase family A, member 4 |
decreases expression |
ISO |
Mercury results in decreased expression of PDIA4 mRNA |
CTD |
PMID:17547211 |
|
NCBI chr 4:78,134,144...78,153,191
|
|
G |
Pds5b |
PDS5 cohesin associated factor B |
decreases expression |
ISO |
Mercury results in decreased expression of PDS5B mRNA |
CTD |
PMID:16823088 |
|
NCBI chr12:5,038,114...5,181,208
|
|
G |
Pex14 |
peroxisomal biogenesis factor 14 |
increases expression |
ISO |
Mercury results in increased expression of PEX14 mRNA |
CTD |
PMID:16823088 |
|
NCBI chr 5:159,399,776...159,536,260
|
|
G |
Pfdn4 |
prefoldin subunit 4 |
decreases expression |
ISO |
Mercury analog results in decreased expression of PFDN4 mRNA |
CTD |
PMID:25056781 |
|
NCBI chr 3:159,303,173...159,311,221
|
|
G |
Pgc |
progastricsin |
decreases expression |
ISO |
Mercury results in decreased expression of PGC mRNA |
CTD |
PMID:17547211 |
|
NCBI chr 9:13,257,462...13,265,682
|
|
G |
Phox2b |
paired-like homeobox 2b |
increases expression |
ISO |
Mercury results in increased expression of PHOX2B mRNA |
CTD |
PMID:16823088 |
|
NCBI chr14:41,420,011...41,424,527
|
|
G |
Pias2 |
protein inhibitor of activated STAT, 2 |
affects expression |
ISO |
Mercury affects the expression of PIAS2 mRNA |
CTD |
PMID:23920476 |
|
NCBI chr18:70,608,034...70,714,295
|
|
G |
Pias4 |
protein inhibitor of activated STAT, 4 |
decreases expression |
EXP |
Mercury results in decreased expression of PIAS4 mRNA |
CTD |
PMID:22688007 |
|
NCBI chr 7:8,546,312...8,559,838
|
|
G |
Pik3r1 |
phosphoinositide-3-kinase regulatory subunit 1 |
decreases expression |
EXP |
Mercury results in decreased expression of PIK3R1 mRNA |
CTD |
PMID:12730625 |
|
NCBI chr 2:34,612,946...34,697,660
|
|
G |
Pik3r4 |
phosphoinositide-3-kinase, regulatory subunit 4 |
increases expression |
ISO |
Mercury results in increased expression of PIK3R4 mRNA |
CTD |
PMID:16823088 |
|
NCBI chr 8:115,146,660...115,195,326
|
|
G |
Pikfyve |
phosphoinositide kinase, FYVE-type zinc finger containing |
decreases expression |
ISO |
Mercury results in decreased expression of PIKFYVE mRNA |
CTD |
PMID:19937285 |
|
NCBI chr 9:74,057,488...74,151,610
|
|
G |
Pld1 |
phospholipase D1 |
increases phosphorylation |
ISO |
Mercury results in increased phosphorylation of PLD1 protein |
CTD |
PMID:21994240 |
|
NCBI chr 2:112,777,820...112,975,857
|
|
G |
Plppr4 |
phospholipid phosphatase related 4 |
increases expression |
ISO |
Mercury results in increased expression of PLPPR4 mRNA |
CTD |
PMID:16823088 |
|
NCBI chr 2:205,371,317...205,412,302
|
|
G |
Plxnb3 |
plexin B3 |
decreases expression |
ISO |
Mercury analog results in decreased expression of PLXNB3 mRNA |
CTD |
PMID:25056781 |
|
NCBI chr X:156,645,505...156,660,011
|
|
G |
Pmch |
pro-melanin-concentrating hormone |
decreases expression |
ISO |
Mercury results in decreased expression of PMCH mRNA |
CTD |
PMID:19937285 |
|
NCBI chr 7:22,511,934...22,513,250
|
|
G |
Pms1 |
PMS1 homolog 1, mismatch repair system component |
decreases expression |
ISO |
Mercury analog results in decreased expression of PMS1 mRNA |
CTD |
PMID:25056781 |
|
NCBI chr 9:55,721,393...55,832,225
|
|
G |
Pnma1 |
PNMA family member 1 |
decreases expression |
ISO |
Mercury results in decreased expression of PNMA1 mRNA |
CTD |
PMID:17547211 |
|
NCBI chr 6:103,782,244...103,784,029
|
|
G |
Pogk |
pogo transposable element derived with KRAB domain |
affects expression |
ISO |
Mercury affects the expression of POGK mRNA |
CTD |
PMID:16823088 |
|
NCBI chr13:78,647,447...78,663,363
|
|
G |
Pold2 |
DNA polymerase delta 2, accessory subunit |
affects expression |
ISO |
Mercury affects the expression of POLD2 mRNA |
CTD |
PMID:16823088 |
|
NCBI chr14:80,748,971...80,755,188
|
|
G |
Pon1 |
paraoxonase 1 |
decreases activity multiple interactions |
ISO |
Mercury results in decreased activity of PON1 protein Selenium inhibits the reaction [Mercury results in decreased activity of PON1 protein] |
CTD |
PMID:21543280 |
|
NCBI chr 4:34,261,312...34,292,327
|
|
G |
Pou2f3 |
POU class 2 homeobox 3 |
increases expression |
ISO |
Mercury results in increased expression of POU2F3 mRNA |
CTD |
PMID:16823088 |
|
NCBI chr 8:43,495,408...43,577,795
|
|
G |
Ppia |
peptidylprolyl isomerase A |
increases expression |
ISO |
Mercury results in increased expression of PPIA mRNA |
CTD |
PMID:16823088 |
|
NCBI chr14:81,279,292...81,282,960
|
|
G |
Ppih |
peptidylprolyl isomerase H |
increases expression |
ISO |
Mercury results in increased expression of PPIH mRNA |
CTD |
PMID:17547211 |
|
NCBI chr 5:132,906,324...132,924,341
|
|
G |
Ppp1r12a |
protein phosphatase 1, regulatory subunit 12A |
increases expression |
ISO |
Mercury results in increased expression of PPP1R12A mRNA |
CTD |
PMID:16823088 |
|
NCBI chr 7:45,368,922...45,480,158
|
|
G |
Ppp1r15a |
protein phosphatase 1, regulatory subunit 15A |
decreases expression |
ISO |
Mercury results in decreased expression of PPP1R15A mRNA |
CTD |
PMID:16823088 |
|
NCBI chr 1:105,136,521...105,139,596
|
|
G |
Ppp3cb |
protein phosphatase 3 catalytic subunit beta |
decreases expression |
ISO |
Mercury results in decreased expression of PPP3CB mRNA |
CTD |
PMID:22008530 |
|
NCBI chr15:3,809,182...3,854,204
|
|
G |
Pprc1 |
PPARG related coactivator 1 |
affects response to substance |
ISO |
PPRC1 protein affects the susceptibility to Mercury |
CTD |
PMID:26942574 |
|
NCBI chr 1:244,901,985...244,918,587
|
|
G |
Ppt2 |
palmitoyl-protein thioesterase 2 |
decreases expression |
ISO |
Mercury results in decreased expression of PPT2 mRNA |
CTD |
PMID:19937285 |
|
NCBI chr20:4,112,520...4,132,774
|
|
G |
Prdx2 |
peroxiredoxin 2 |
increases expression |
EXP |
Mercury results in increased expression of PRDX2 mRNA |
CTD |
PMID:12730625 |
|
NCBI chr19:23,180,927...23,186,217
|
|
G |
Prdx6 |
peroxiredoxin 6 |
decreases expression increases expression |
ISO |
Mercury results in decreased expression of PRDX6 mRNA Mercury analog results in increased expression of PRDX6 mRNA |
CTD |
PMID:16823088 PMID:25056781 |
|
NCBI chr13:73,528,746...73,539,295
|
|
G |
Prkca |
protein kinase C, alpha |
increases expression |
EXP |
Mercury results in increased expression of PRKCA mRNA |
CTD |
PMID:12730625 |
|
NCBI chr10:93,388,991...93,787,617
|
|
G |
Prkcg |
protein kinase C, gamma |
increases expression |
EXP |
Mercury results in increased expression of PRKCG mRNA |
CTD |
PMID:12730625 |
|
NCBI chr 1:74,748,272...74,777,611
|
|
G |
Prkcq |
protein kinase C, theta |
decreases expression |
ISO |
Mercury analog results in decreased expression of PRKCQ mRNA |
CTD |
PMID:25056781 |
|
NCBI chr17:72,156,215...72,288,508
|
|
G |
Prpf31 |
pre-mRNA processing factor 31 |
decreases expression |
ISO |
Mercury analog results in decreased expression of PRPF31 mRNA |
CTD |
PMID:25056781 |
|
NCBI chr 1:65,575,887...65,587,561
|
|
G |
Prpf40a |
pre-mRNA processing factor 40 homolog A |
decreases expression |
ISO |
Mercury analog results in decreased expression of PRPF40A mRNA |
CTD |
PMID:25056781 |
|
NCBI chr 3:37,625,585...37,689,859
|
|
G |
Psph |
phosphoserine phosphatase |
decreases expression |
ISO |
Mercury results in decreased expression of PSPH mRNA |
CTD |
PMID:17547211 |
|
NCBI chr12:26,882,524...26,905,084
|
|
G |
Ptbp1 |
polypyrimidine tract binding protein 1 |
decreases expression |
ISO |
Mercury analog results in decreased expression of PTBP1 mRNA |
CTD |
PMID:25056781 |
|
NCBI chr 7:9,842,574...9,852,332
|
|
G |
Ptger2 |
prostaglandin E receptor 2 |
increases expression |
EXP |
Mercury results in increased expression of PTGER2 mRNA |
CTD |
PMID:12730625 |
|
NCBI chr15:18,215,013...18,228,714
|
|
G |
Ptov1 |
PTOV1, extended AT-hook containing adaptor protein |
decreases expression |
ISO |
Mercury analog results in decreased expression of PTOV1 mRNA |
CTD |
PMID:25056781 |
|
NCBI chr 1:95,347,065...95,354,514
|
|
G |
Pttg1 |
PTTG1 regulator of sister chromatid separation, securin |
increases expression |
ISO |
Mercury results in increased expression of PTTG1 mRNA |
CTD |
PMID:17547211 |
|
NCBI chr10:28,394,940...28,406,410
|
|
G |
Purb |
purine rich element binding protein B |
increases expression |
ISO |
Mercury analog results in increased expression of PURB mRNA |
CTD |
PMID:25056781 |
|
NCBI chr14:81,342,374...81,344,857
|
|
G |
Pvalb |
parvalbumin |
decreases expression |
ISO |
Mercury analog results in decreased expression of PVALB mRNA |
CTD |
PMID:25056781 |
|
NCBI chr 7:111,653,820...111,668,469
|
|
G |
Pxdn |
peroxidasin |
decreases expression |
ISO |
Mercury results in decreased expression of PXDN mRNA |
CTD |
PMID:19937285 |
|
NCBI chr 6:46,580,749...46,658,345
|
|
G |
Pxn |
paxillin |
affects localization |
ISO |
Mercury affects the localization of PXN protein |
CTD |
PMID:26600472 |
|
NCBI chr12:41,060,791...41,107,952
|
|
G |
Rac1 |
Rac family small GTPase 1 |
increases expression |
ISO |
Mercury results in increased expression of RAC1 mRNA |
CTD |
PMID:16823088 |
|
NCBI chr12:16,150,411...16,170,864
|
|
G |
Racgap1 |
Rac GTPase-activating protein 1 |
increases expression |
ISO |
Mercury results in increased expression of RACGAP1 mRNA |
CTD |
PMID:17547211 |
|
NCBI chr 7:132,629,789...132,659,738
|
|
G |
Rad18 |
RAD18 E3 ubiquitin protein ligase |
decreases expression |
ISO |
Mercury results in decreased expression of RAD18 mRNA |
CTD |
PMID:22641096 |
|
NCBI chr 4:145,735,654...145,821,102
|
|
G |
Ralgapa1 |
Ral GTPase activating protein catalytic subunit alpha 1 |
decreases expression |
ISO |
Mercury results in decreased expression of RALGAPA1 mRNA |
CTD |
PMID:19937285 |
|
NCBI chr 6:72,977,432...73,252,378
|
|
G |
Rara |
retinoic acid receptor, alpha |
decreases expression |
EXP |
Mercury results in decreased expression of RARA mRNA |
CTD |
PMID:22688007 |
|
NCBI chr10:83,883,490...83,928,932
|
|
G |
Rbfox3 |
RNA binding fox-1 homolog 3 |
multiple interactions |
ISO |
[diethyl phosphate co-treated with Cotinine co-treated with bis(2,3,3,3-tetrachloropropyl) ether co-treated with Mercury co-treated with Selenium] results in increased expression of RBFOX3 mRNA |
CTD |
PMID:37914285 |
|
NCBI chr10:103,720,355...104,157,277
|
|
G |
Rbm22 |
RNA binding motif protein 22 |
decreases expression |
ISO |
Mercury analog results in decreased expression of RBM22 mRNA |
CTD |
PMID:25056781 |
|
NCBI chr18:56,283,807...56,294,615
|
|
G |
Rbpms |
RNA binding protein, mRNA processing factor |
increases expression |
ISO |
Mercury results in increased expression of RBPMS mRNA |
CTD |
PMID:17547211 |
|
NCBI chr16:58,239,370...58,395,424
|
|
G |
Rela |
RELA proto-oncogene, NF-kB subunit |
multiple interactions |
ISO EXP |
Mercury inhibits the reaction [lipopolysaccharide, E. coli O26-B6 results in increased localization of RELA protein] Mercury inhibits the reaction [Lipopolysaccharides results in increased activity of [RELA protein binds to NFKB1 protein]]; Mercury inhibits the reaction [TNF protein results in increased activity of [RELA protein binds to NFKB1 protein]] [Copper co-treated with Lead co-treated with Cadmium co-treated with Zinc co-treated with Mercury co-treated with Chromium co-treated with Manganese co-treated with Nickel] results in increased expression of RELA protein |
CTD |
PMID:11437639 PMID:15282405 PMID:28035397 |
|
NCBI chr 1:212,354,336...212,364,815
|
|
G |
Reln |
reelin |
decreases expression |
ISO |
Mercury results in decreased expression of RELN mRNA |
CTD |
PMID:17547211 |
|
NCBI chr 4:12,736,177...13,162,956
|
|
G |
Rhobtb2 |
Rho-related BTB domain containing 2 |
increases expression |
ISO |
Mercury results in increased expression of RHOBTB2 mRNA |
CTD |
PMID:16823088 |
|
NCBI chr15:44,868,251...44,888,436
|
|
G |
Rnaseh1 |
ribonuclease H1 |
decreases expression |
ISO |
Mercury results in decreased expression of RNASEH1 mRNA |
CTD |
PMID:16823088 |
|
NCBI chr 6:45,282,849...45,292,258
|
|
G |
Rnaseh2a |
ribonuclease H2, subunit A |
decreases expression increases expression |
ISO |
Mercury results in decreased expression of RNASEH2A mRNA Mercury results in increased expression of RNASEH2A mRNA |
CTD |
PMID:16823088 PMID:17547211 |
|
NCBI chr19:40,091,206...40,100,904
|
|
G |
Rnd2 |
Rho family GTPase 2 |
increases methylation |
ISO |
Mercury results in increased methylation of RND2 gene |
CTD |
PMID:21606628 |
|
NCBI chr10:86,399,151...86,402,750
|
|
G |
Rnf138 |
ring finger protein 138 |
increases expression |
ISO |
Mercury results in increased expression of RNF138 mRNA |
CTD |
PMID:16823088 |
|
NCBI chr18:12,291,557...12,315,931
|
|
G |
Rnf141 |
ring finger protein 141 |
decreases expression |
ISO |
Mercury results in decreased expression of RNF141 mRNA |
CTD |
PMID:19937285 |
|
NCBI chr 1:164,933,972...164,957,081
|
|
G |
Rngtt |
RNA guanylyltransferase and 5'-phosphatase |
affects expression |
ISO |
Mercury affects the expression of RNGTT mRNA |
CTD |
PMID:16823088 |
|
NCBI chr 5:47,706,929...47,913,297
|
|
G |
Rpl19 |
ribosomal protein L19 |
decreases expression |
ISO |
Mercury results in decreased expression of RPL19 mRNA |
CTD |
PMID:16823088 |
|
NCBI chr10:83,022,503...83,026,030
|
|
G |
Rpl28 |
ribosomal protein L28 |
decreases expression |
ISO |
Mercury results in decreased expression of RPL28 mRNA |
CTD |
PMID:16823088 |
|
NCBI chr 1:69,052,148...69,054,735
|
|
G |
Rpp21 |
ribonuclease P/MRP subunit p21 |
decreases expression |
ISO |
Mercury analog results in decreased expression of RPP21 mRNA |
CTD |
PMID:25056781 |
|
NCBI chr20:1,986,225...2,025,308
|
|
G |
Rps5 |
ribosomal protein S5 |
decreases expression |
ISO |
Mercury results in decreased expression of RPS5 mRNA |
CTD |
PMID:16823088 |
|
NCBI chr 1:73,538,776...73,543,073
|
|
G |
Rps6kc1 |
ribosomal protein S6 kinase C1 |
decreases expression |
ISO |
Mercury analog results in decreased expression of RPS6KC1 mRNA |
CTD |
PMID:25056781 |
|
NCBI chr13:104,877,296...105,021,490
|
|
G |
Rrbp1 |
ribosome binding protein 1 |
decreases expression |
ISO |
Mercury results in decreased expression of RRBP1 mRNA |
CTD |
PMID:19937285 |
|
NCBI chr 3:131,314,996...131,376,930
|
|
G |
Rsad2 |
radical S-adenosyl methionine domain containing 2 |
multiple interactions |
ISO |
[Mercuric Chloride results in increased abundance of Mercury] which results in increased expression of RSAD2 mRNA |
CTD |
PMID:28453771 |
|
NCBI chr 6:48,774,985...48,788,245
|
|
G |
RT1-Ba |
RT1 class II, locus Ba |
decreases expression |
ISO |
Mercury results in decreased expression of HLA-DQA1 mRNA |
CTD |
PMID:16823088 PMID:19937285 |
|
NCBI chr20:4,575,134...4,579,727
|
|
G |
RT1-Bb |
RT1 class II, locus Bb |
increases expression decreases expression |
EXP ISO |
Mercury results in increased expression of RT1-BB mRNA Mercury results in increased expression of HLA-DQB1 mRNA Mercury results in decreased expression of HLA-DQB1 mRNA |
CTD |
PMID:16823088 PMID:19937285 PMID:22688007 |
|
NCBI chr20:4,598,475...4,604,118
|
|
G |
Rtn4 |
reticulon 4 |
decreases expression |
ISO |
Mercury results in decreased expression of RTN4 mRNA |
CTD |
PMID:19937285 |
|
NCBI chr14:103,450,074...103,497,687
|
|
G |
Rtp3 |
receptor (chemosensory) transporter protein 3 |
decreases expression |
ISO |
Mercury results in decreased expression of RTP3 mRNA |
CTD |
PMID:22008530 |
|
NCBI chr 8:110,970,154...110,975,000
|
|
G |
Rubcnl |
rubicon like autophagy enhancer |
increases expression |
ISO |
Mercury results in increased expression of RUBCNL mRNA |
CTD |
PMID:16823088 |
|
NCBI chr15:50,332,458...50,377,494
|
|
G |
S100a4 |
S100 calcium-binding protein A4 |
decreases expression |
ISO |
Mercury analog results in decreased expression of S100A4 mRNA |
CTD |
PMID:25056781 |
|
NCBI chr 2:178,388,529...178,390,838
|
|
G |
S100b |
S100 calcium binding protein B |
increases secretion |
ISO |
Mercury results in increased secretion of S100B mRNA |
CTD |
PMID:30076900 |
|
NCBI chr20:12,372,345...12,381,159
|
|
G |
Sap30 |
Sin3A associated protein 30 |
increases expression |
ISO |
Mercury results in increased expression of SAP30 mRNA |
CTD |
PMID:16823088 |
|
NCBI chr16:32,747,777...32,753,114
|
|
G |
Scaf4 |
SR-related CTD-associated factor 4 |
increases expression |
ISO |
Mercury results in increased expression of SCAF4 mRNA |
CTD |
PMID:16823088 |
|
NCBI chr11:29,460,479...29,521,153
|
|
G |
Scarb1 |
scavenger receptor class B, member 1 |
increases expression |
ISO |
Mercury results in increased expression of SCARB1 mRNA |
CTD |
PMID:19937285 |
|
NCBI chr12:36,957,302...37,023,982
|
|
G |
Scg3 |
secretogranin III |
increases expression |
ISO |
Mercury results in increased expression of SCG3 mRNA |
CTD |
PMID:16823088 |
|
NCBI chr 8:76,399,777...76,442,015
|
|
G |
Sec24c |
SEC24 homolog C, COPII coat complex component |
increases expression |
ISO |
Mercury results in increased expression of SEC24C mRNA |
CTD |
PMID:16823088 |
|
NCBI chr15:3,602,460...3,624,524
|
|
G |
Selenop |
selenoprotein P |
affects abundance increases expression multiple interactions |
ISO |
SELENOP gene polymorphism affects the abundance of Mercury Mercury results in increased expression of SELENOP protein [Mercury results in increased expression of SELENOP protein] which results in increased abundance of Selenium; SELENOP protein binds to and results in decreased susceptibility to Mercury |
CTD |
PMID:16451871 PMID:21967774 PMID:27989593 |
|
NCBI chr 2:52,498,123...52,508,409
|
|
G |
Senp6 |
SUMO specific peptidase 6 |
increases expression |
ISO |
Mercury results in increased expression of SENP6 mRNA |
CTD |
PMID:16823088 |
|
NCBI chr 8:80,988,675...81,071,606
|
|
G |
Serpina3n |
serpin family A member 3N |
affects expression |
ISO |
Mercury affects the expression of SERPINA3 protein |
CTD |
PMID:22030286 |
|
NCBI chr 6:123,323,623...123,331,181
|
|
G |
Serpinb1a |
serpin family B member 1A |
decreases expression |
ISO |
Mercury results in decreased expression of SERPINB1 mRNA |
CTD |
PMID:17547211 |
|
NCBI chr17:31,590,695...31,599,102
|
|
G |
Serpinc1 |
serpin family C member 1 |
decreases expression |
ISO |
Mercury results in decreased expression of SERPINC1 mRNA |
CTD |
PMID:17547211 |
|
NCBI chr13:75,790,558...75,804,826
|
|
G |
Serping1 |
serpin family G member 1 |
affects expression |
ISO |
Mercury affects the expression of SERPING1 protein |
CTD |
PMID:22030286 |
|
NCBI chr 3:90,249,410...90,259,299
|
|
G |
Sfrp1 |
secreted frizzled-related protein 1 |
decreases expression |
ISO |
Mercury results in decreased expression of SFRP1 mRNA |
CTD |
PMID:19937285 |
|
NCBI chr16:75,278,325...75,316,736
|
|
G |
Sh3bp2 |
SH3-domain binding protein 2 |
increases expression |
ISO |
Mercury results in increased expression of SH3BP2 mRNA |
CTD |
PMID:19937285 |
|
NCBI chr14:76,176,097...76,213,300
|
|
G |
Sh3glb2 |
SH3 domain-containing GRB2-like endophilin B2 |
increases expression |
ISO |
Mercury results in increased expression of SH3GLB2 mRNA |
CTD |
PMID:16823088 |
|
NCBI chr 3:13,616,936...13,631,785
|
|
G |
Sh3pxd2a |
SH3 and PX domains 2A |
increases expression |
ISO |
Mercury results in increased expression of SH3PXD2A mRNA |
CTD |
PMID:16823088 |
|
NCBI chr 1:256,094,991...256,301,120
|
|
G |
Shc1 |
SHC adaptor protein 1 |
decreases expression |
ISO |
Mercury results in decreased expression of SHC1 mRNA |
CTD |
PMID:16823088 |
|
NCBI chr 2:177,135,649...177,147,257
|
|
G |
Sirt5 |
sirtuin 5 |
decreases expression |
ISO |
Mercury analog results in decreased expression of SIRT5 mRNA |
CTD |
PMID:25056781 |
|
NCBI chr17:21,310,028...21,337,137
|
|
G |
Slc11a1 |
solute carrier family 11 member 1 |
increases expression |
ISO |
Mercury results in increased expression of SLC11A1 mRNA |
CTD |
PMID:19937285 |
|
NCBI chr 9:75,957,193...75,968,115
|
|
G |
Slc11a2 |
solute carrier family 11 member 2 |
decreases expression multiple interactions increases uptake |
ISO |
Mercury results in decreased expression of SLC11A2 mRNA [HAMP protein results in decreased expression of SLC11A2 mRNA] which results in decreased uptake of Mercury SLC11A2 mRNA results in increased uptake of Mercury SLC11A2 results in increased uptake of Mercury |
CTD |
PMID:25772431 |
|
NCBI chr 7:131,503,076...131,540,246
|
|
G |
Slc12a2 |
solute carrier family 12 member 2 |
affects transport |
EXP |
SLC12A2 protein mutant form affects the transport of Mercury |
CTD |
PMID:12556450 |
|
NCBI chr18:51,348,282...51,416,448
|
|
G |
Slc18a2 |
solute carrier family 18 member A2 |
decreases expression |
ISO |
Mercury analog results in decreased expression of SLC18A2 mRNA |
CTD |
PMID:25056781 |
|
NCBI chr 1:258,413,748...258,449,143
|
|
G |
Slc22a1 |
solute carrier family 22 member 1 |
increases expression |
EXP |
Mercury results in increased expression of SLC22A1 mRNA |
CTD |
PMID:12730625 |
|
NCBI chr 1:50,624,339...50,651,437
|
|
G |
Slc22a19 |
solute carrier family 22, member 19 |
multiple interactions increases expression |
EXP |
EPO protein inhibits the reaction [Mercury results in increased expression of SLC22A19 protein] |
CTD |
PMID:32909846 |
|
NCBI chr 1:204,910,450...204,965,538
|
|
G |
Slc22a4 |
solute carrier family 22 member 4 |
multiple interactions |
ISO |
Acetylcysteine inhibits the reaction [Mercury results in decreased activity of SLC22A4 protein]; Cysteine inhibits the reaction [Mercury results in decreased activity of SLC22A4 protein]; Dithioerythritol inhibits the reaction [Mercury results in decreased activity of SLC22A4 protein]; Mercury binds to and results in decreased activity of SLC22A4 protein |
CTD |
PMID:25490951 |
|
NCBI chr10:38,133,333...38,179,932
|
|
G |
Slc22a6 |
solute carrier family 22 member 6 |
multiple interactions affects response to substance |
ISO EXP |
SLC22A6 gene SNP affects the susceptibility to and affects the abundance of Mercury; SLC22A6 protein results in increased transport of [Acetylcysteine co-treated with Mercury] SLC22A6 gene SNP affects the susceptibility to Mercury EPO protein promotes the reaction [Mercury results in increased expression of and affects the localization of SLC22A6 protein]; Mercury results in increased expression of and affects the localization of SLC22A6 protein |
CTD |
PMID:15908511 PMID:23052037 PMID:32909846 PMID:32946573 |
|
NCBI chr 1:205,522,579...205,531,179
|
|
G |
Slc22a8 |
solute carrier family 22 member 8 |
multiple interactions |
ISO EXP |
[SLC22A8 gene SNP affects the susceptibility to Mercury] which affects the abundance of Mercury; SLC22A8 gene SNP affects the susceptibility to and affects the abundance of Mercury EPO protein affects the reaction [Mercury affects the localization of SLC22A8 protein]; EPO protein promotes the reaction [Mercury results in increased expression of SLC22A8 protein]; Mercury results in increased expression of and affects the localization of SLC22A8 protein |
CTD |
PMID:23052037 PMID:32909846 PMID:32946573 |
|
NCBI chr 1:205,496,331...205,516,378
|
|
G |
Slc25a22 |
solute carrier family 25 member 22 |
decreases expression |
ISO |
Mercury results in decreased expression of SLC25A22 mRNA |
CTD |
PMID:19937285 |
|
NCBI chr 1:205,954,713...205,966,188
|
|
G |
Slc2a4 |
solute carrier family 2 member 4 |
decreases expression |
EXP |
Mercury results in decreased expression of SLC2A4 mRNA |
CTD |
PMID:22688007 |
|
NCBI chr10:55,164,721...55,170,289
|
|
G |
Slc30a1 |
solute carrier family 30 member 1 |
increases expression |
EXP |
Mercury results in increased expression of SLC30A1 mRNA |
CTD |
PMID:12730625 |
|
NCBI chr13:106,022,019...106,025,892
|
|
G |
Slc39a8 |
solute carrier family 39 member 8 |
multiple interactions |
ISO |
Mercury inhibits the reaction [SLC39A8 protein results in increased uptake of Cadmium] |
CTD |
PMID:16638970 |
|
NCBI chr 2:224,171,787...224,319,326
|
|
G |
Slc3a2 |
solute carrier family 3 member 2 |
affects import |
ISO |
SLC3A2 protein affects the import of Mercury |
CTD |
PMID:28786956 |
|
NCBI chr 1:215,033,601...215,048,064
|
|
G |
Slc6a4 |
solute carrier family 6 member 4 |
affects response to substance |
ISO |
SLC6A4 promoter polymorphism affects the susceptibility to Mercury |
CTD |
PMID:20526950 |
|
NCBI chr10:62,322,688...62,357,060
|
|
G |
Slc7a2 |
solute carrier family 7 member 2 |
decreases expression |
ISO |
Mercury results in decreased expression of SLC7A2 mRNA |
CTD |
PMID:19937285 |
|
NCBI chr16:51,417,478...51,470,784
|
|
G |
Slc7a5 |
solute carrier family 7 member 5 |
multiple interactions |
ISO |
SLC7A5 gene SNP affects the susceptibility to and affects the abundance of Mercury |
CTD |
PMID:23052037 |
|
NCBI chr19:66,843,808...66,872,412
|
|
G |
Slit3 |
slit guidance ligand 3 |
decreases expression |
ISO |
Mercury results in decreased expression of SLIT3 mRNA |
CTD |
PMID:16823088 |
|
NCBI chr10:20,075,929...20,660,704
|
|
G |
Smad2 |
SMAD family member 2 |
increases expression |
ISO |
Mercury results in increased expression of SMAD2 mRNA |
CTD |
PMID:19937285 |
|
NCBI chr18:72,124,792...72,193,345
|
|
G |
Smc4 |
structural maintenance of chromosomes 4 |
increases expression |
ISO |
Mercury results in increased expression of SMC4 mRNA |
CTD |
PMID:17547211 |
|
NCBI chr 2:153,240,243...153,268,722
|
|
G |
Smim14 |
small integral membrane protein 14 |
increases expression |
ISO |
Mercury results in increased expression of SMIM14 mRNA |
CTD |
PMID:16823088 |
|
NCBI chr14:43,136,754...43,180,622
|
|
G |
Snrpa |
small nuclear ribonucleoprotein polypeptide A |
increases expression |
ISO |
Mercury results in increased expression of SNRPA mRNA |
CTD |
PMID:17547211 |
|
NCBI chr 1:82,481,770...82,490,540
|
|
G |
Sod1 |
superoxide dismutase 1 |
increases expression multiple interactions |
EXP |
Mercury results in increased expression of SOD1 mRNA [Mercury co-treated with Hydrogen Peroxide] results in increased expression of SOD1 mRNA |
CTD |
PMID:23578882 |
|
NCBI chr11:42,942,742...42,948,399
|
|
G |
Sos1 |
SOS Ras/Rac guanine nucleotide exchange factor 1 |
decreases expression |
ISO |
Mercury analog results in decreased expression of SOS1 mRNA |
CTD |
PMID:25056781 |
|
NCBI chr 6:20,286,117...20,363,350
|
|
G |
Sox18 |
SRY-box transcription factor 18 |
increases expression |
ISO |
Mercury results in increased expression of SOX18 mRNA |
CTD |
PMID:16823088 |
|
NCBI chr 3:168,785,488...168,787,290
|
|
G |
Spink1 |
serine peptidase inhibitor, Kazal type 1 |
decreases expression |
EXP |
Mercury results in decreased expression of SPINK1 mRNA |
CTD |
PMID:22688007 |
|
NCBI chr18:35,870,723...35,882,693
|
|
G |
Spp1 |
secreted phosphoprotein 1 |
increases expression |
ISO |
Mercury results in increased expression of SPP1 mRNA |
CTD |
PMID:17547211 |
|
NCBI chr14:5,613,569...5,620,695
|
|
G |
Sptbn1 |
spectrin, beta, non-erythrocytic 1 |
increases expression |
ISO |
Mercury results in increased expression of SPTBN1 mRNA |
CTD |
PMID:16823088 |
|
NCBI chr14:103,841,713...104,016,900
|
|
G |
Srf |
serum response factor |
decreases expression |
ISO |
Mercury results in decreased expression of SRF mRNA |
CTD |
PMID:16823088 |
|
NCBI chr 9:21,924,050...21,933,338
|
|
G |
Srpk3 |
SRSF protein kinase 3 |
decreases expression |
ISO |
Mercury analog results in decreased expression of SRPK3 mRNA |
CTD |
PMID:25056781 |
|
NCBI chr X:156,661,888...156,666,537
|
|
G |
Srsf2 |
serine and arginine rich splicing factor 2 |
increases expression |
ISO |
Mercury results in increased expression of SRSF2 mRNA |
CTD |
PMID:17547211 |
|
NCBI chr10:102,052,158...102,055,365
|
|
G |
Srsf7 |
serine and arginine rich splicing factor 7 |
increases expression |
ISO |
Mercury results in increased expression of SRSF7 mRNA |
CTD |
PMID:17547211 |
|
NCBI chr 6:20,564,035...20,571,205
|
|
G |
Ssbp1 |
single stranded DNA binding protein 1 |
increases expression |
ISO |
Mercury results in increased expression of SSBP1 mRNA |
CTD |
PMID:19937285 |
|
NCBI chr 4:70,232,740...70,242,824
|
|
G |
Ssr2 |
signal sequence receptor subunit 2 |
decreases expression |
ISO |
Mercury results in decreased expression of SSR2 mRNA |
CTD |
PMID:16823088 |
|
NCBI chr 2:174,048,291...174,057,043
|
|
G |
Sstr3 |
somatostatin receptor 3 |
decreases expression |
ISO |
Mercury results in decreased expression of SSTR3 mRNA |
CTD |
PMID:19937285 |
|
NCBI chr 7:110,092,563...110,109,043
|
|
G |
Stk24 |
serine/threonine kinase 24 |
decreases expression |
ISO |
Mercury analog results in decreased expression of STK24 mRNA |
CTD |
PMID:25056781 |
|
NCBI chr15:104,770,556...104,866,524
|
|
G |
Stub1 |
STIP1 homology and U-box containing protein 1 |
decreases expression |
ISO |
Mercury results in decreased expression of STUB1 mRNA |
CTD |
PMID:19937285 |
|
NCBI chr10:14,850,765...14,853,046
|
|
G |
Sub1 |
SUB1 regulator of transcription |
decreases expression |
ISO |
Mercury results in decreased expression of SUB1 mRNA |
CTD |
PMID:19937285 |
|
NCBI chr 2:61,005,646...61,020,486
|
|
G |
Szrd1 |
SUZ RNA binding domain containing 1 |
affects expression |
ISO |
Mercury affects the expression of SZRD1 mRNA |
CTD |
PMID:16823088 |
|
NCBI chr 5:153,418,748...153,443,286
|
|
G |
Tac1 |
tachykinin, precursor 1 |
increases expression |
ISO |
Mercury results in increased expression of TAC1 mRNA |
CTD |
PMID:16823088 |
|
NCBI chr 4:36,645,344...36,653,548
|
|
G |
Tap1 |
transporter 1, ATP binding cassette subfamily B member |
decreases expression |
EXP |
Mercury results in decreased expression of TAP1 mRNA |
CTD |
PMID:22688007 |
|
NCBI chr20:4,658,171...4,668,543
|
|
G |
Tardbp |
TAR DNA binding protein |
multiple interactions |
ISO |
[methylmercuric chloride results in increased abundance of Mercury] which affects the localization of TARDBP protein |
CTD |
PMID:30371865 |
|
NCBI chr 5:164,330,452...164,348,435
|
|
G |
Tat |
tyrosine aminotransferase |
increases activity multiple interactions |
EXP |
Mercury results in increased activity of TAT protein Mercury inhibits the reaction [Dexamethasone results in increased activity of TAT protein] |
CTD |
PMID:16307467 |
|
NCBI chr19:37,947,153...37,957,717
|
|
G |
Tcf3 |
transcription factor 3 |
decreases expression |
ISO |
Mercury results in decreased expression of TCF3 mRNA |
CTD |
PMID:19937285 |
|
NCBI chr 7:9,931,251...9,952,994
|
|
G |
Tes |
testin LIM domain protein |
decreases expression |
ISO |
Mercury results in decreased expression of TES mRNA |
CTD |
PMID:22008530 |
|
NCBI chr 4:45,365,304...45,403,829
|
|
G |
Tf |
transferrin |
increases secretion |
ISO |
Mercury results in increased secretion of TF protein |
CTD |
PMID:10798623 |
|
NCBI chr 8:103,789,780...103,816,487
|
|
G |
Tgfb2 |
transforming growth factor, beta 2 |
increases expression |
ISO |
Mercury results in increased expression of TGFB2 mRNA |
CTD |
PMID:16823088 |
|
NCBI chr13:98,160,075...98,261,771
|
|
G |
Them6 |
thioesterase superfamily member 6 |
decreases expression |
ISO |
Mercury analog results in decreased expression of THEM6 mRNA |
CTD |
PMID:25056781 |
|
NCBI chr 7:108,495,554...108,498,731
|
|
G |
Thumpd2 |
THUMP domain containing 2 |
decreases expression |
ISO |
Mercury analog results in decreased expression of THUMPD2 mRNA |
CTD |
PMID:25056781 |
|
NCBI chr 6:13,924,742...13,976,657
|
|
G |
Thumpd3 |
THUMP domain containing 3 |
decreases expression |
ISO |
Mercury results in decreased expression of THUMPD3 mRNA |
CTD |
PMID:22008530 |
|
NCBI chr 4:146,185,422...146,209,802
|
|
G |
Timm13 |
translocase of inner mitochondrial membrane 13 |
decreases expression |
EXP |
Mercury results in decreased expression of TIMM13 mRNA |
CTD |
PMID:22688007 |
|
NCBI chr 7:9,459,490...9,460,849
|
|
G |
Timm23 |
translocase of inner mitochondrial membrane 23 |
increases expression |
EXP |
Mercury results in increased expression of TIMM23 mRNA |
CTD |
PMID:22688007 |
|
NCBI chr16:7,410,308...7,436,392
|
|
G |
Tjp1 |
tight junction protein 1 |
decreases expression |
ISO |
Mercury results in decreased expression of TJP1 mRNA |
CTD |
PMID:37137463 |
|
NCBI chr 1:128,260,330...128,505,018
|
|
G |
Tk2 |
thymidine kinase 2 |
affects expression |
ISO |
Mercury affects the expression of TK2 mRNA |
CTD |
PMID:16823088 |
|
NCBI chr19:713,043...737,345
|
|
G |
Tm2d1 |
TM2 domain containing 1 |
increases expression |
ISO |
Mercury results in increased expression of TM2D1 mRNA |
CTD |
PMID:16823088 |
|
NCBI chr 5:118,136,299...118,177,639
|
|
G |
Tmf1 |
TATA element modulatory factor 1 |
decreases expression |
ISO |
Mercury results in decreased expression of TMF1 mRNA |
CTD |
PMID:16823088 |
|
NCBI chr 4:131,316,630...131,345,666
|
|
G |
Tnf |
tumor necrosis factor |
increases expression multiple interactions affects expression |
EXP ISO |
Mercury results in increased expression of TNF mRNA Mercury promotes the reaction [Lipopolysaccharides results in increased secretion of TNF protein] Mercury results in increased expression of TNF protein Mercury affects the expression of TNF mRNA [Aluminum co-treated with Lead co-treated with Mercury co-treated with Manganese] results in increased expression of TNF protein; [Lead co-treated with Cadmium co-treated with Mercury co-treated with Arsenic] results in increased expression of TNF protein; [Selenium co-treated with Zinc] inhibits the reaction [[Lead co-treated with Cadmium co-treated with Mercury co-treated with Arsenic] results in increased expression of TNF protein]; Mercury inhibits the reaction [TNF protein results in increased activity of [RELA protein binds to NFKB1 protein]]; Selenium inhibits the reaction [[Lead co-treated with Cadmium co-treated with Mercury co-treated with Arsenic] results in increased expression of TNF protein]; Zinc inhibits the reaction [[Lead co-treated with Cadmium co-treated with Mercury co-treated with Arsenic] results in increased expression of TNF protein] [Mercuric Chloride results in increased abundance of Mercury] which results in increased expression of TNF mRNA; CASP1 gene mutant form inhibits the reaction [[Mercuric Chloride results in increased abundance of Mercury] which results in increased expression of TNF mRNA]; IFNG gene mutant form inhibits the reaction [[Mercuric Chloride results in increased abundance of Mercury] which results in increased expression of TNF mRNA]; IL6 gene mutant form inhibits the reaction [[Mercuric Chloride results in increased abundance of Mercury] which results in increased expression of TNF mRNA]; N-(3-propylcarbamoyloxirane-2-carbonyl)-isoleucyl-proline inhibits the reaction [Mercury results in increased expression of TNF mRNA] Mercury results in increased expression of TNF mRNA; Mercury results in increased expression of TNF protein |
CTD |
PMID:12730625 PMID:12928768 PMID:15282405 PMID:20176347 PMID:20600710 PMID:25237059 PMID:28453771 PMID:37137463 PMID:37415728 PMID:37676925 More...
|
|
NCBI chr20:3,626,685...3,629,303
|
|
G |
Tnfaip3 |
TNF alpha induced protein 3 |
increases expression |
ISO |
Mercury results in increased expression of TNFAIP3 mRNA |
CTD |
PMID:17547211 |
|
NCBI chr 1:15,528,921...15,543,993
|
|
G |
Tnfaip8 |
TNF alpha induced protein 8 |
increases expression decreases expression |
ISO EXP |
Mercury results in increased expression of TNFAIP8 mRNA Mercury results in decreased expression of TNFAIP8 mRNA |
CTD |
PMID:17547211 PMID:22688007 |
|
NCBI chr18:45,370,334...45,486,036
|
|
G |
Tnfrsf1a |
TNF receptor superfamily member 1A |
increases expression |
EXP |
Mercury results in increased expression of TNFRSF1A mRNA; Mercury results in increased expression of TNFRSF1A protein |
CTD |
PMID:12730625 |
|
NCBI chr 4:159,837,119...159,849,817
|
|
G |
Tnfsf10 |
TNF superfamily member 10 |
decreases expression |
ISO |
Mercury results in decreased expression of TNFSF10 mRNA |
CTD |
PMID:17547211 |
|
NCBI chr 2:112,136,550...112,155,903
|
|
G |
Tns2 |
tensin 2 |
decreases expression |
ISO |
Mercury analog results in decreased expression of TNS2 mRNA |
CTD |
PMID:25056781 |
|
NCBI chr 7:133,229,746...133,247,889
|
|
G |
Tox3 |
TOX high mobility group box family member 3 |
increases expression |
ISO |
Mercury results in increased expression of TOX3 mRNA |
CTD |
PMID:16823088 |
|
NCBI chr19:16,648,338...16,757,151
|
|
G |
Tp53 |
tumor protein p53 |
affects folding |
ISO |
Mercury affects the folding of TRP53 protein |
CTD |
PMID:8467489 |
|
NCBI chr10:54,798,871...54,810,300
|
|
G |
Tpm2 |
tropomyosin 2 |
increases expression |
ISO |
Mercury results in increased expression of TPM2 mRNA |
CTD |
PMID:16823088 |
|
NCBI chr 5:62,566,712...62,576,066
|
|
G |
Tradd |
TNFRSF1A-associated via death domain |
increases expression |
EXP |
Mercury results in increased expression of TRADD protein |
CTD |
PMID:12730625 |
|
NCBI chr19:50,046,057...50,048,158
|
|
G |
Trib3 |
tribbles pseudokinase 3 |
decreases expression |
ISO |
Mercury results in decreased expression of TRIB3 mRNA |
CTD |
PMID:19937285 |
|
NCBI chr 3:161,269,939...161,275,533
|
|
G |
Trip13 |
thyroid hormone receptor interactor 13 |
increases expression |
ISO |
Mercury results in increased expression of TRIP13 mRNA |
CTD |
PMID:17547211 |
|
NCBI chr 1:29,357,093...29,402,078
|
|
G |
Tspan7 |
tetraspanin 7 |
decreases expression |
ISO |
Mercury results in decreased expression of TSPAN7 mRNA |
CTD |
PMID:17547211 |
|
NCBI chr X:12,208,783...12,306,092
|
|
G |
Tst |
thiosulfate sulfurtransferase |
decreases expression |
ISO |
Mercury results in decreased expression of TST mRNA |
CTD |
PMID:17547211 |
|
NCBI chr 7:111,828,557...111,836,980
|
|
G |
Tuba8 |
tubulin, alpha 8 |
decreases expression |
ISO |
Mercury analog results in decreased expression of TUBA8 mRNA |
CTD |
PMID:25056781 |
|
NCBI chr 4:156,110,562...156,129,065
|
|
G |
Twf2 |
twinfilin actin-binding protein 2 |
decreases expression |
ISO |
Mercury results in decreased expression of TWF2 mRNA |
CTD |
PMID:16823088 |
|
NCBI chr 8:115,723,980...115,737,025
|
|
G |
Txn1 |
thioredoxin 1 |
affects binding |
ISO |
Mercury binds to TXN protein |
CTD |
PMID:18321861 |
|
NCBI chr 5:77,507,455...77,519,685
|
|
G |
Txndc11 |
thioredoxin domain containing 11 |
decreases expression |
ISO |
Mercury analog results in decreased expression of TXNDC11 mRNA |
CTD |
PMID:25056781 |
|
NCBI chr10:4,515,457...4,572,999
|
|
G |
Txnrd1 |
thioredoxin reductase 1 |
increases expression |
ISO |
Mercury results in increased expression of TXNRD1 mRNA |
CTD |
PMID:17547211 |
|
NCBI chr 7:22,717,620...22,802,553
|
|
G |
Txnrd2 |
thioredoxin reductase 2 |
decreases activity |
EXP |
Mercury results in decreased activity of TXNRD2 protein |
CTD |
PMID:17157198 |
|
NCBI chr11:82,519,996...82,568,156
|
|
G |
Tyms |
thymidylate synthetase |
increases expression |
ISO |
Mercury results in increased expression of TYMS mRNA |
CTD |
PMID:17547211 |
|
NCBI chr 9:120,760,057...120,776,149
|
|
G |
Ube2c |
ubiquitin-conjugating enzyme E2C |
increases expression |
ISO |
Mercury results in increased expression of UBE2C mRNA |
CTD |
PMID:17547211 |
|
NCBI chr 3:173,925,975...173,928,375
|
|
G |
Ube2l3 |
ubiquitin-conjugating enzyme E2L 3 |
decreases expression |
ISO |
Mercury analog results in decreased expression of UBE2L3 mRNA |
CTD |
PMID:25056781 |
|
NCBI chr11:83,797,722...83,838,862
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G |
Ube2n |
ubiquitin-conjugating enzyme E2N |
decreases expression |
ISO |
Mercury results in decreased expression of UBE2N mRNA |
CTD |
PMID:16823088 |
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NCBI chr 7:30,154,330...30,184,373
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G |
Ugcg |
UDP-glucose ceramide glucosyltransferase |
increases expression |
ISO |
Mercury results in increased expression of UGCG mRNA |
CTD |
PMID:17547211 |
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NCBI chr 5:78,828,006...78,860,725
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G |
Uqcrb |
ubiquinol-cytochrome c reductase binding protein |
increases expression |
ISO |
Mercury results in increased expression of UQCRB mRNA |
CTD |
PMID:16823088 |
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NCBI chr 7:65,700,016...65,705,382
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G |
Urod |
uroporphyrinogen decarboxylase |
decreases activity |
ISO |
Mercury results in decreased activity of UROD protein |
CTD |
PMID:15967199 |
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NCBI chr 5:135,701,294...135,705,380
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G |
Usp39 |
ubiquitin specific peptidase 39 |
increases expression |
ISO |
Mercury results in increased expression of USP39 mRNA |
CTD |
PMID:16823088 |
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NCBI chr 4:104,373,948...104,406,359
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G |
Usp53 |
ubiquitin specific peptidase 53 |
decreases expression |
ISO |
Mercury analog results in decreased expression of USP53 mRNA |
CTD |
PMID:25056781 |
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NCBI chr 2:211,059,512...211,120,942
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G |
Uspl1 |
ubiquitin specific peptidase like 1 |
increases expression |
ISO |
Mercury results in increased expression of USPL1 mRNA |
CTD |
PMID:16823088 |
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NCBI chr12:5,823,460...5,850,470
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G |
Vasp |
vasodilator-stimulated phosphoprotein |
decreases expression |
ISO |
Mercury analog results in decreased expression of VASP mRNA |
CTD |
PMID:25056781 |
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NCBI chr 1:88,038,026...88,053,783
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|
G |
Vdr |
vitamin D receptor |
affects abundance |
ISO |
VDR gene polymorphism affects the abundance of Mercury |
CTD |
PMID:25728017 |
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NCBI chr 7:130,864,764...130,916,757
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G |
Vim |
vimentin |
increases expression |
ISO |
Mercury results in increased expression of VIM mRNA |
CTD |
PMID:26600472 |
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NCBI chr17:81,577,261...81,585,746
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G |
Vps36 |
vacuolar protein sorting 36 homolog |
decreases expression |
ISO |
Mercury analog results in decreased expression of VPS36 mRNA |
CTD |
PMID:25056781 |
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NCBI chr16:69,810,404...69,834,789
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G |
Vtn |
vitronectin |
decreases expression |
ISO |
Mercury results in decreased expression of VTN mRNA |
CTD |
PMID:17547211 |
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NCBI chr10:63,394,732...63,397,812
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|
G |
Vwa1 |
von Willebrand factor A domain containing 1 |
increases expression |
ISO |
Mercury results in increased expression of VWA1 mRNA |
CTD |
PMID:16823088 |
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NCBI chr 5:171,659,694...171,664,880
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G |
Wdr12 |
WD repeat domain 12 |
decreases expression |
EXP |
Mercury results in decreased expression of WDR12 mRNA |
CTD |
PMID:22688007 |
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NCBI chr 9:61,475,498...61,502,762
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G |
Wipi1 |
WD repeat domain, phosphoinositide interacting 1 |
decreases expression |
ISO |
Mercury results in decreased expression of WIPI1 mRNA |
CTD |
PMID:22008530 |
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NCBI chr10:95,042,451...95,079,679
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G |
Xist |
X inactive specific transcript |
increases expression |
ISO |
Mercury results in increased expression of XIST mRNA |
CTD |
PMID:22008530 |
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NCBI chr X:68,474,987...68,492,500
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G |
Ybx1 |
Y box binding protein 1 |
increases expression |
ISO |
Mercury results in increased expression of YBX1 mRNA |
CTD |
PMID:16823088 |
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NCBI chr 5:138,167,444...138,188,155
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G |
Ywhaq |
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta |
decreases expression |
ISO |
Mercury analog results in decreased expression of YWHAQ mRNA |
CTD |
PMID:25056781 |
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NCBI chr 6:46,664,358...46,694,875
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G |
Ywhaz |
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta |
decreases expression |
ISO |
Mercury results in decreased expression of YWHAZ mRNA |
CTD |
PMID:16823088 |
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NCBI chr 7:69,826,404...69,848,702
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G |
Zbtb1 |
zinc finger and BTB domain containing 1 |
increases expression |
ISO |
Mercury results in increased expression of ZBTB1 mRNA |
CTD |
PMID:16823088 |
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NCBI chr 6:95,096,838...95,125,811
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G |
Zbtb10 |
zinc finger and BTB domain containing 10 |
increases expression |
ISO |
Mercury results in increased expression of ZBTB10 mRNA |
CTD |
PMID:16823088 |
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NCBI chr 2:94,382,670...94,417,308
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G |
Zbtb16 |
zinc finger and BTB domain containing 16 |
increases expression |
ISO |
Mercury results in increased expression of ZBTB16 mRNA |
CTD |
PMID:19937285 |
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NCBI chr 8:57,885,886...58,073,507
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G |
Zbtb38 |
zinc finger and BTB domain containing 38 |
increases expression |
ISO |
Mercury results in increased expression of ZBTB38 mRNA |
CTD |
PMID:19937285 |
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NCBI chr 8:97,284,617...97,288,518
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G |
Zfand3 |
zinc finger AN1-type containing 3 |
decreases expression |
ISO |
Mercury analog results in decreased expression of ZFAND3 mRNA |
CTD |
PMID:25056781 |
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NCBI chr20:8,083,407...8,279,617
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G |
Zfhx4 |
zinc finger homeobox 4 |
decreases expression |
ISO |
Mercury analog results in decreased expression of ZFHX4 mRNA |
CTD |
PMID:25056781 |
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NCBI chr 2:96,224,763...96,408,245
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G |
Zfp174 |
zinc finger protein 174 |
decreases expression |
ISO |
Mercury results in decreased expression of ZNF174 mRNA |
CTD |
PMID:19937285 |
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NCBI chr10:11,666,580...11,676,328
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|
G |
Zfp866 |
zinc finger protein 866 |
increases expression |
EXP |
Mercury results in increased expression of CXCL5 mRNA |
CTD |
PMID:12730625 |
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NCBI chr16:19,653,966...19,675,968
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|
G |
Zfp950 |
zinc finger protein 950 |
increases expression |
ISO |
Mercury results in increased expression of ZNF80 mRNA |
CTD |
PMID:16823088 |
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NCBI chr 1:260,248,231...260,265,211
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G |
Zwint |
ZW10 interacting kinetochore protein |
increases expression |
ISO |
Mercury results in increased expression of ZWINT mRNA |
CTD |
PMID:17547211 |
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NCBI chr20:15,502,559...15,953,701
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