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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:DDT
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Accession:CHEBI:16130 term browser browse the term
Definition:A chlorophenylethane that is 1,1,1-trichloro-2,2-diphenylethane substituted by additional chloro substituents at positions 4 of the phenyl substituents. It is a commonly used organochlorine insecticide.
Synonyms:exact_synonym: 1-chloro-4-[2,2,2-trichloro-1-(4-chlorophenyl)ethyl]benzene
 related_synonym: 1,1'-(2,2,2-trichloroethylidene)bis[4-chlorobenzene];   1,1,1-Trichloro-2,2-bis(4-chlorophenyl)ethane;   1,1-bis(4-chlorophenyl)-2,2,2-trichloroethane;   4,4'-DDT;   Formula=C14H9Cl5;   InChI=1S/C14H9Cl5/c15-11-5-1-9(2-6-11)13(14(17,18)19)10-3-7-12(16)8-4-10/h1-8,13H;   InChIKey=YVGGHNCTFXOJCH-UHFFFAOYSA-N;   SMILES=Clc1ccc(cc1)C(c1ccc(Cl)cc1)C(Cl)(Cl)Cl;   alpha,alpha-bis(p-chlorophenyl)-beta,beta,beta-trichlorethane;   clofenotane;   dichlorodiphenyltrichloroethane;   p,p'-DDT;   p,p'-dichlorodiphenyltrichloroethane
 alt_id: CHEBI:11129;   CHEBI:18849;   CHEBI:472
 xref: Beilstein:1882657;   CAS:50-29-3;   Drug_Central:4396;   Gmelin:509864;   HMDB:HMDB0032127;   KEGG:C04623;   KEGG:D07367;   LINCS:LSM-19015
 xref_mesh: MESH:D003634
 xref: MetaCyc:CPD-43;   PMID:17949680;   PMID:24328540;   PPDB:3140;   Reaxys:1882657;   UM-BBD_compID:c0384;   Wikipedia:DDT


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DDT term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abca1 ATP binding cassette subfamily A member 1 decreases expression ISO DDT results in decreased expression of ABCA1 protein CTD PMID:25720399 NCBI chr 5:69,857,717...69,983,042
Ensembl chr 5:69,857,771...69,983,015
JBrowse link
G Abcb1a ATP binding cassette subfamily B member 1A decreases activity
increases expression
ISO
EXP
DDT metabolite results in decreased activity of ABCB1 protein
DDT results in increased expression of ABCB1 mRNA
CTD PMID:15710169, PMID:23169446, PMID:24464585, PMID:29477483 NCBI chr 4:22,339,829...22,517,642
Ensembl chr 4:22,133,521...22,425,515
JBrowse link
G Abcc2 ATP binding cassette subfamily C member 2 increases expression ISO DDT results in increased expression of ABCC2 mRNA CTD PMID:24464585, PMID:31521043 NCBI chr 1:263,554,426...263,612,556
Ensembl chr 1:263,554,453...263,613,252
JBrowse link
G Abcg2 ATP binding cassette subfamily G member 2 decreases activity ISO DDT metabolite results in decreased activity of ABCG2 protein CTD PMID:23169446 NCBI chr 4:88,765,441...88,890,268
Ensembl chr 4:88,832,178...88,890,621
JBrowse link
G Ablim1 actin-binding LIM protein 1 increases methylation EXP DDT results in increased methylation of ABLIM1 gene CTD PMID:30207508 NCBI chr 1:277,853,877...278,043,096 JBrowse link
G Ace angiotensin I converting enzyme decreases expression EXP DDT results in decreased expression of ACE mRNA CTD PMID:30207508 NCBI chr10:94,170,766...94,213,831
Ensembl chr10:94,170,766...94,187,822
JBrowse link
G Ache acetylcholinesterase increases expression ISO DDT results in increased expression of ACHE mRNA CTD PMID:31521043 NCBI chr12:22,472,358...22,477,052
Ensembl chr12:22,472,358...22,478,753
JBrowse link
G Acsbg2 acyl-CoA synthetase bubblegum family member 2 decreases methylation EXP DDT results in decreased methylation of ACSBG2 gene CTD PMID:30207508 NCBI chr 9:10,172,317...10,203,550
Ensembl chr 9:10,172,832...10,203,460
JBrowse link
G Acss2 acyl-CoA synthetase short-chain family member 2 increases expression EXP DDT results in increased expression of ACSS2 mRNA CTD PMID:29477483 NCBI chr 3:151,032,925...151,075,856
Ensembl chr 3:151,032,952...151,075,856
JBrowse link
G Acss3 acyl-CoA synthetase short-chain family member 3 decreases expression EXP DDT results in decreased expression of ACSS3 mRNA CTD PMID:30207508 NCBI chr 7:49,047,022...49,250,953
Ensembl chr 7:49,047,013...49,250,957
JBrowse link
G Acta2 actin alpha 2, smooth muscle increases expression EXP DDT results in increased expression of ACTA2 mRNA CTD PMID:30207508 NCBI chr 1:252,537,614...252,550,394
Ensembl chr 1:252,537,615...252,550,394
JBrowse link
G Actb actin, beta decreases expression ISO DDT results in decreased expression of ACTB protein CTD PMID:26186133 NCBI chr12:13,715,843...13,718,813
Ensembl chr12:13,715,843...13,718,841
JBrowse link
G Actg2 actin gamma 2, smooth muscle increases expression EXP DDT results in increased expression of ACTG2 mRNA CTD PMID:30207508 NCBI chr 4:115,215,160...115,239,746
Ensembl chr 4:115,215,060...115,239,723
JBrowse link
G Adamts5 ADAM metallopeptidase with thrombospondin type 1 motif, 5 decreases expression EXP DDT results in decreased expression of ADAMTS5 mRNA CTD PMID:30207508 NCBI chr11:25,411,174...25,456,639
Ensembl chr11:25,410,975...25,456,836
JBrowse link
G Adrb2 adrenoceptor beta 2 affects activity EXP DDT affects the activity of ADRB2 protein CTD PMID:17157474 NCBI chr18:57,513,792...57,515,834
Ensembl chr18:57,513,793...57,515,834
JBrowse link
G Agmo alkylglycerol monooxygenase increases methylation EXP DDT results in increased methylation of AGMO gene CTD PMID:30207508 NCBI chr 6:56,846,859...57,193,918
Ensembl chr 6:56,846,789...57,193,961
JBrowse link
G Ahr aryl hydrocarbon receptor multiple interactions
decreases expression
affects binding
ISO [indole-3-carbinol co-treated with DDT] results in increased expression of AHR mRNA
DDT results in decreased expression of AHR mRNA
DDT binds to AHR protein
CTD PMID:17311112, PMID:20436506, PMID:31521043 NCBI chr 6:54,963,990...55,001,806
Ensembl chr 6:54,963,990...55,001,464
JBrowse link
G Akr1b10 aldo-keto reductase family 1 member B10 increases expression ISO DDT results in increased expression of AKR1B10 mRNA CTD PMID:26198647 NCBI chr 4:61,813,265...61,830,371
Ensembl chr 4:61,771,970...61,828,657
JBrowse link
G Alas1 5'-aminolevulinate synthase 1 increases expression EXP DDT results in increased expression of ALAS1 mRNA CTD PMID:30207508 NCBI chr 8:114,927,704...114,941,038
Ensembl chr 8:114,927,722...114,940,177
JBrowse link
G Alb albumin decreases expression ISO DDT results in decreased expression of ALB mRNA CTD PMID:22902829 NCBI chr14:19,176,275...19,191,793
Ensembl chr14:19,176,277...19,191,863
JBrowse link
G Alcam activated leukocyte cell adhesion molecule decreases expression EXP DDT results in decreased expression of ALCAM mRNA CTD PMID:30207508 NCBI chr11:50,780,735...50,985,083
Ensembl chr11:50,781,127...50,985,083
JBrowse link
G Alk ALK receptor tyrosine kinase multiple interactions ISO [Hexachlorocyclohexane co-treated with Aldrin co-treated with Dieldrin co-treated with Endrin co-treated with Dichlorodiphenyl Dichloroethylene co-treated with Dichlorodiphenyldichloroethane co-treated with DDT co-treated with Simvastatin] results in decreased expression of ALK mRNA CTD PMID:28263720 NCBI chr 6:22,696,415...23,203,791
Ensembl chr 6:22,696,397...23,203,775
JBrowse link
G Alpl alkaline phosphatase, biomineralization associated multiple interactions ISO DDT inhibits the reaction [Aldosterone results in increased expression of ALPL mRNA] CTD PMID:29149346 NCBI chr 5:156,086,496...156,141,513
Ensembl chr 5:156,086,497...156,141,537
JBrowse link
G Alyref Aly/REF export factor increases methylation EXP DDT results in increased methylation of ALYREF gene CTD PMID:30207508 NCBI chr10:109,768,593...109,774,639
Ensembl chr10:109,770,876...109,774,639
JBrowse link
G Anapc11 anaphase promoting complex subunit 11 increases methylation EXP DDT results in increased methylation of ANAPC11 gene CTD PMID:30207508 NCBI chr10:109,774,779...109,785,877
Ensembl chr10:109,774,878...109,785,877
JBrowse link
G Anks1b ankyrin repeat and sterile alpha motif domain containing 1B increases methylation EXP DDT results in increased methylation of ANKS1B gene CTD PMID:30207508 NCBI chr 7:30,507,135...31,684,604
Ensembl chr 7:30,699,476...31,681,182
JBrowse link
G Anpep alanyl aminopeptidase, membrane decreases expression EXP DDT results in decreased expression of ANPEP mRNA CTD PMID:30207508 NCBI chr 1:141,561,364...141,604,249
Ensembl chr 1:141,561,334...141,604,273
JBrowse link
G Antxr1 ANTXR cell adhesion molecule 1 increases methylation EXP DDT results in increased methylation of ANTXR1 gene CTD PMID:30207508 NCBI chr 4:118,946,267...119,131,202
Ensembl chr 4:118,946,268...119,131,202
JBrowse link
G Anxa1 annexin A1 decreases expression EXP DDT results in decreased expression of ANXA1 mRNA CTD PMID:30207508 NCBI chr 1:237,893,983...237,910,002
Ensembl chr 1:237,893,966...237,910,012
JBrowse link
G Ap2a2 adaptor related protein complex 2 subunit alpha 2 increases methylation EXP DDT results in increased methylation of AP2A2 gene CTD PMID:30207508 NCBI chr 1:214,534,217...214,607,497
Ensembl chr 1:214,534,284...214,606,169
JBrowse link
G App amyloid beta precursor protein increases expression
multiple interactions
ISO DDT results in increased expression of APP protein
DDT results in increased expression of and results in increased cleavage of APP protein mutant form; DDT results in increased expression of and results in increased secretion of and results in decreased degradation of APP protein modified form
CTD PMID:24473795, PMID:25720399 NCBI chr11:24,425,013...24,641,872
Ensembl chr11:24,425,005...24,641,858
JBrowse link
G Ar androgen receptor multiple interactions
affects binding
ISO
EXP
[DDT analog co-treated with Hexachlorocyclohexane analog co-treated with Chlorobenzenes co-treated with Mirex co-treated with Polychlorinated Biphenyls co-treated with Chlordan co-treated with Toxaphene co-treated with Hydrocarbons, Chlorinated] inhibits the reaction [Dihydrotestosterone results in increased expression of AR mRNA]; DDT binds to and results in decreased activity of AR protein; DDT inhibits the reaction [Dihydrotestosterone binds to and results in increased activity of AR protein]; DDT inhibits the reaction [Dihydrotestosterone binds to AR protein]; DDT inhibits the reaction [Dihydrotestosterone results in increased activity of AR protein]; DDT inhibits the reaction [Dihydrotestosterone results in increased expression of AR mRNA]; DDT inhibits the reaction [Metribolone affects the localization of AR protein]; DDT inhibits the reaction [Metribolone promotes the reaction [AR protein binds to KLK3 promoter]]; DDT inhibits the reaction [Metribolone results in increased expression of AR protein]; Dihydrotestosterone inhibits the reaction [DDT results in increased activity of AR protein]
DDT binds to AR protein
CTD PMID:9705896, PMID:14565775, PMID:14579009, PMID:15064155, PMID:15483189, PMID:21295777, PMID:25682698, PMID:26022396 NCBI chr  X:67,656,253...67,828,998
Ensembl chr  X:67,656,253...67,829,026
JBrowse link
G Arap2 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2 decreases expression EXP DDT results in decreased expression of ARAP2 mRNA CTD PMID:30207508 NCBI chr14:48,726,033...48,922,809
Ensembl chr14:48,726,045...48,922,983
JBrowse link
G Arf1 ADP-ribosylation factor 1 decreases expression EXP DDT results in decreased expression of ARF1 mRNA CTD PMID:19797855 NCBI chr10:45,562,700...45,579,214
Ensembl chr10:45,563,547...45,579,029
JBrowse link
G Arfgef1 ADP ribosylation factor guanine nucleotide exchange factor 1 decreases expression EXP DDT results in decreased expression of ARFGEF1 mRNA CTD PMID:30207508 NCBI chr 5:8,666,046...8,760,458
Ensembl chr 5:8,666,200...8,760,458
JBrowse link
G Arhgap10 Rho GTPase activating protein 10 increases methylation EXP DDT results in increased methylation of ARHGAP10 gene CTD PMID:30207508 NCBI chr19:34,138,978...34,406,593
Ensembl chr19:34,139,997...34,402,436
JBrowse link
G Arhgap15 Rho GTPase activating protein 15 decreases methylation EXP DDT results in decreased methylation of ARHGAP15 gene CTD PMID:30207508 NCBI chr 3:28,626,987...29,236,225
Ensembl chr 3:28,627,084...29,236,219
JBrowse link
G Arhgap5 Rho GTPase activating protein 5 decreases expression EXP DDT results in decreased expression of ARHGAP5 mRNA CTD PMID:30207508 NCBI chr 6:73,345,129...73,408,304
Ensembl chr 6:73,345,392...73,405,880
JBrowse link
G Arhgap6 Rho GTPase activating protein 6 decreases expression EXP DDT results in decreased expression of ARHGAP6 mRNA CTD PMID:30207508 NCBI chr  X:26,314,561...26,845,242
Ensembl chr  X:26,315,878...26,376,467
JBrowse link
G Arhgef33 Rho guanine nucleotide exchange factor 33 increases methylation EXP DDT results in increased methylation of ARHGEF33 gene CTD PMID:30207508 NCBI chr 6:2,982,324...3,100,358
Ensembl chr 6:3,012,804...3,095,500
JBrowse link
G Arl2 ADP-ribosylation factor like GTPase 2 decreases expression EXP DDT results in decreased expression of ARL2 mRNA CTD PMID:30207508 NCBI chr 1:221,504,150...221,516,191
Ensembl chr 1:221,504,170...221,516,110
JBrowse link
G Arsb arylsulfatase B decreases methylation EXP DDT results in decreased methylation of ARSB gene CTD PMID:30207508 NCBI chr 2:23,385,154...23,543,028
Ensembl chr 2:23,385,183...23,544,963
JBrowse link
G Atf3 activating transcription factor 3 increases expression EXP DDT results in increased expression of ATF3 mRNA CTD PMID:30207508 NCBI chr13:109,817,892...109,849,632
Ensembl chr13:109,817,728...109,849,632
JBrowse link
G Atp1a1 ATPase Na+/K+ transporting subunit alpha 1 multiple interactions ISO [o,p'-DDT co-treated with DDT] results in increased expression of ATP1A1 mRNA CTD PMID:27325568 NCBI chr 2:204,003,742...204,032,023
Ensembl chr 2:204,003,742...204,032,023
JBrowse link
G Atrnl1 attractin like 1 increases methylation EXP DDT results in increased methylation of ATRNL1 gene CTD PMID:30207508 NCBI chr 1:278,546,113...279,098,977
Ensembl chr 1:278,557,792...278,815,473
JBrowse link
G Bace1 beta-secretase 1 increases expression ISO DDT results in increased expression of BACE1 CTD PMID:25720399 NCBI chr 8:50,140,092...50,162,388
Ensembl chr 8:50,139,997...50,162,361
JBrowse link
G Bcap29 B-cell receptor-associated protein 29 decreases expression EXP DDT results in decreased expression of BCAP29 mRNA CTD PMID:30207508 NCBI chr 6:50,883,758...50,923,743
Ensembl chr 6:50,883,787...50,923,510
JBrowse link
G Bcat1 branched chain amino acid transaminase 1 decreases expression EXP DDT results in decreased expression of BCAT1 mRNA CTD PMID:30207508 NCBI chr 4:179,259,305...179,340,021
Ensembl chr 4:179,259,308...179,339,795
JBrowse link
G Bche butyrylcholinesterase decreases expression EXP DDT results in decreased expression of BCHE mRNA CTD PMID:30207508 NCBI chr 2:171,104,476...171,196,186
Ensembl chr 2:171,100,140...171,196,395
JBrowse link
G Bcl2 BCL2, apoptosis regulator multiple interactions
decreases expression
ISO [DDT results in increased activity of ESR1 protein] which results in increased expression of BCL2 mRNA
DDT results in decreased expression of BCL2 protein
CTD PMID:22403704, PMID:28263910 NCBI chr13:26,605,426...26,769,374
Ensembl chr13:26,605,426...26,769,374
JBrowse link
G Bdnf brain-derived neurotrophic factor multiple interactions ISO [Permethrin co-treated with DDT co-treated with Diethylstilbestrol] inhibits the reaction [Potassium results in increased expression of BDNF mRNA]; DDT inhibits the reaction [Potassium results in increased expression of BDNF mRNA] CTD PMID:15527870 NCBI chr 3:100,768,637...100,819,216
Ensembl chr 3:100,768,637...100,819,210
JBrowse link
G Bgn biglycan increases expression EXP DDT results in increased expression of BGN mRNA CTD PMID:30207508 NCBI chr  X:157,319,042...157,331,204
Ensembl chr  X:157,319,046...157,331,204
JBrowse link
G Bhlha15 basic helix-loop-helix family, member a15 multiple interactions ISO [Hexachlorocyclohexane co-treated with Aldrin co-treated with Dieldrin co-treated with Endrin co-treated with Dichlorodiphenyl Dichloroethylene co-treated with Dichlorodiphenyldichloroethane co-treated with DDT co-treated with Simvastatin] results in decreased expression of BHLHA15 mRNA CTD PMID:28263720 NCBI chr12:12,403,385...12,409,103
Ensembl chr12:12,403,385...12,407,561
JBrowse link
G Birc6 baculoviral IAP repeat-containing 6 increases methylation EXP DDT results in increased methylation of BIRC6 gene CTD PMID:30207508 NCBI chr 6:21,900,763...22,092,484
Ensembl chr 6:21,950,100...22,092,346
JBrowse link
G Bmf Bcl2 modifying factor decreases expression EXP DDT results in decreased expression of BMF mRNA CTD PMID:30207508 NCBI chr 3:110,303,515...110,324,125
Ensembl chr 3:110,306,067...110,324,084
JBrowse link
G Bod1l1 biorientation of chromosomes in cell division 1-like 1 decreases expression EXP DDT results in decreased expression of BOD1L1 mRNA CTD PMID:30207508 NCBI chr14:73,738,137...73,792,935
Ensembl chr14:73,738,137...73,791,656
JBrowse link
G Btg2 BTG anti-proliferation factor 2 increases expression EXP DDT results in increased expression of BTG2 mRNA CTD PMID:30207508 NCBI chr13:50,913,185...50,916,944
Ensembl chr13:50,913,180...50,916,982
JBrowse link
G Cacna2d3 calcium voltage-gated channel auxiliary subunit alpha2delta 3 decreases methylation EXP DDT results in decreased methylation of CACNA2D3 gene CTD PMID:30207508 NCBI chr16:4,871,348...5,795,825
Ensembl chr16:4,871,650...5,795,825
JBrowse link
G Cadps calcium dependent secretion activator decreases expression EXP DDT results in decreased expression of CADPS mRNA CTD PMID:30207508 NCBI chr15:15,275,489...15,690,575
Ensembl chr15:15,275,541...15,667,778
JBrowse link
G Calb2 calbindin 2 increases expression EXP DDT results in increased expression of CALB2 mRNA CTD PMID:30207508 NCBI chr19:41,482,743...41,509,617
Ensembl chr19:41,482,728...41,509,658
JBrowse link
G Cald1 caldesmon 1 decreases expression EXP DDT results in decreased expression of CALD1 mRNA CTD PMID:30207508 NCBI chr 4:62,103,948...62,291,375
Ensembl chr 4:62,220,736...62,291,489
JBrowse link
G Calhm2 calcium homeostasis modulator family member 2 decreases expression EXP DDT results in decreased expression of CALHM2 mRNA CTD PMID:30207508 NCBI chr 1:266,908,367...266,914,093
Ensembl chr 1:266,908,369...266,914,093
JBrowse link
G Camk2d calcium/calmodulin-dependent protein kinase II delta increases methylation EXP DDT results in increased methylation of CAMK2D gene CTD PMID:30207508 NCBI chr 2:230,900,907...231,132,207
Ensembl chr 2:230,901,126...231,132,039
JBrowse link
G Canx calnexin decreases expression EXP DDT results in decreased expression of CANX mRNA CTD PMID:30207508 NCBI chr10:35,800,942...35,833,939
Ensembl chr10:35,800,942...35,833,861
JBrowse link
G Capn2 calpain 2 increases methylation EXP DDT results in increased methylation of CAPN2 gene CTD PMID:30207508 NCBI chr13:100,878,649...100,928,811
Ensembl chr13:100,878,650...100,928,811
JBrowse link
G Carmn cardiac mesoderm enhancer-associated non-coding RNA increases expression ISO DDT results in increased expression of CARMN mRNA CTD PMID:25014179
G Casp3 caspase 3 increases activity
multiple interactions
decreases activity
ISO
EXP
DDT results in increased activity of CASP3 protein
SB 203580 inhibits the reaction [DDT results in increased activity of CASP3 protein]
DDT inhibits the reaction [TGFB1 protein results in increased activity of CASP3 protein]
DDT results in decreased activity of CASP3 protein
CTD PMID:10200566, PMID:15603917 NCBI chr16:48,845,011...48,863,249
Ensembl chr16:48,845,012...48,863,204
JBrowse link
G Casp7 caspase 7 increases activity
multiple interactions
ISO DDT results in increased activity of CASP7 protein
SB 203580 inhibits the reaction [DDT results in increased activity of CASP7 protein]
CTD PMID:15603917 NCBI chr 1:277,190,557...277,242,779
Ensembl chr 1:277,190,964...277,242,774
JBrowse link
G Cat catalase multiple interactions EXP [Polychlorinated Biphenyls co-treated with Dichlorodiphenyl Dichloroethylene co-treated with Dichlorodiphenyldichloroethane co-treated with DDT co-treated with Chlordan co-treated with nonachlor] inhibits the reaction [Fish Oils results in increased expression of CAT mRNA] CTD PMID:28659405 NCBI chr 3:93,379,872...93,412,058
Ensembl chr 3:93,379,874...93,412,058
JBrowse link
G Cbln1 cerebellin 1 precursor decreases expression EXP DDT results in decreased expression of CBLN1 mRNA CTD PMID:30207508 NCBI chr19:20,607,507...20,611,316
Ensembl chr19:20,607,507...20,611,316
JBrowse link
G Ccn3 cellular communication network factor 3 decreases expression EXP DDT results in decreased expression of NOV mRNA CTD PMID:30207508 NCBI chr 7:94,375,134...94,382,154
Ensembl chr 7:94,375,020...94,383,024
JBrowse link
G Ccnd1 cyclin D1 multiple interactions
increases expression
ISO DDT promotes the reaction [ESR1 protein binds to CCND1 promoter]; DDT promotes the reaction [FOS protein binds to CCND1 promoter]
Acetylcysteine inhibits the reaction [DDT results in increased phosphorylation of CCND1 protein]
DDT results in increased expression of CCND1 protein
DDT results in increased expression of CCND1 mRNA; DDT results in increased expression of CCND1 protein
CTD PMID:8927716, PMID:9049186, PMID:23684557, PMID:24968063 NCBI chr 1:218,090,750...218,100,447
Ensembl chr 1:218,090,750...218,100,325
JBrowse link
G Ccnd2 cyclin D2 decreases expression ISO DDT results in decreased expression of CCND2 mRNA CTD PMID:25014179 NCBI chr 4:159,674,885...159,697,207
Ensembl chr 4:159,674,885...159,697,207
JBrowse link
G Cd244 CD244 molecule increases methylation EXP DDT results in increased methylation of CD244 gene CTD PMID:30207508 NCBI chr13:89,959,091...89,995,993
Ensembl chr13:89,975,267...89,995,974
JBrowse link
G Cd2ap CD2-associated protein decreases expression EXP DDT results in decreased expression of CD2AP mRNA CTD PMID:30207508 NCBI chr 9:20,794,680...20,858,438
Ensembl chr 9:20,765,296...20,858,504
JBrowse link
G Cd34 CD34 molecule increases expression EXP DDT results in increased expression of CD34 mRNA CTD PMID:30207508 NCBI chr13:113,691,842...113,711,259
Ensembl chr13:113,691,932...113,711,647
JBrowse link
G Cd86 CD86 molecule multiple interactions ISO DDT inhibits the reaction [endotoxin, Escherichia coli results in increased expression of CD86 protein] CTD PMID:28412309 NCBI chr11:67,060,305...67,117,990
Ensembl chr11:67,082,193...67,118,795
JBrowse link
G Cdh1 cadherin 1 multiple interactions
decreases expression
ISO Acetylcysteine inhibits the reaction [DDT results in decreased expression of CDH1 mRNA]; DDT inhibits the reaction [CDH1 protein binds to CTNNB1 protein]; INCB018424 inhibits the reaction [DDT results in decreased expression of CDH1 mRNA]; WP1066 inhibits the reaction [DDT results in decreased expression of CDH1 mRNA]
DDT results in decreased expression of CDH1 mRNA; DDT results in decreased expression of CDH1 protein
CTD PMID:22902829, PMID:24820114 NCBI chr19:38,768,467...38,838,395
Ensembl chr19:38,768,467...38,838,395
JBrowse link
G Cdh2 cadherin 2 multiple interactions
increases expression
ISO Acetylcysteine inhibits the reaction [DDT results in increased expression of CDH2 mRNA]; INCB018424 inhibits the reaction [DDT results in increased expression of CDH2 mRNA]; WP1066 inhibits the reaction [DDT results in increased expression of CDH2 mRNA] CTD PMID:24820114 NCBI chr18:8,146,971...8,366,037
Ensembl chr18:8,146,971...8,360,684
JBrowse link
G Cdk2 cyclin dependent kinase 2 increases activity
multiple interactions
ISO DDT results in increased activity of CDK2 protein
DDT results in increased phosphorylation of and results in increased activity of CDK2 protein; fulvestrant inhibits the reaction [DDT results in increased phosphorylation of and results in increased activity of CDK2 protein]
CTD PMID:8927716, PMID:9049186, PMID:9168006 NCBI chr 7:3,124,953...3,132,533
Ensembl chr 7:3,124,954...3,132,457
JBrowse link
G Cdk4 cyclin-dependent kinase 4 increases expression ISO DDT results in increased expression of CDK4 protein CTD PMID:23684557 NCBI chr 7:70,345,971...70,352,689
Ensembl chr 7:70,349,863...70,352,418
JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A multiple interactions
decreases expression
ISO DDT inhibits the reaction [TRP53 protein binds to CDKN1A promoter]; DDT promotes the reaction [ESR1 protein binds to CDKN1A promoter]
DDT results in decreased expression of CDKN1A mRNA
CTD PMID:23684557 NCBI chr20:6,348,422...6,358,864
Ensembl chr20:6,351,458...6,358,864
JBrowse link
G Cdkn2a cyclin-dependent kinase inhibitor 2A decreases expression
increases methylation
EXP DDT results in decreased expression of CDKN2A mRNA alternative form; DDT results in decreased expression of CDKN2A protein alternative form
DDT results in increased methylation of CDKN2A promoter alternative form
CTD PMID:25410620 NCBI chr 5:107,823,323...107,832,405
Ensembl chr 5:107,823,330...107,841,175
JBrowse link
G Cebpa CCAAT/enhancer binding protein alpha multiple interactions ISO DDT results in increased activity of and results in increased localization of CEBPA protein CTD PMID:11911853 NCBI chr 1:91,363,492...91,366,164
Ensembl chr 1:91,363,492...91,366,164
JBrowse link
G Cemip cell migration inducing hyaluronidase decreases expression EXP DDT results in decreased expression of CEMIP mRNA CTD PMID:30207508 NCBI chr 1:146,069,774...146,226,320
Ensembl chr 1:146,069,771...146,226,462
JBrowse link
G Cep170b centrosomal protein 170B increases methylation EXP DDT results in increased methylation of CEP170B gene CTD PMID:30207508 NCBI chr 6:137,283,814...137,311,512
Ensembl chr 6:137,288,810...137,311,932
JBrowse link
G Ces1d carboxylesterase 1D increases methylation EXP DDT results in increased methylation of CES1D gene CTD PMID:30207508 NCBI chr19:15,195,514...15,239,827
Ensembl chr19:15,033,108...15,239,821
JBrowse link
G Ces3a carboxylesterase 3a increases expression EXP DDT results in increased expression of CES3 mRNA CTD PMID:29477483 NCBI chr19:37,070,705...37,079,411 JBrowse link
G Cftr CF transmembrane conductance regulator multiple interactions ISO DDT inhibits the reaction [S-Nitrosoglutathione results in increased expression of and results in increased stability of CFTR protein] CTD PMID:14766015 NCBI chr 4:42,693,263...42,860,679
Ensembl chr 4:42,692,836...42,860,676
JBrowse link
G Cga glycoprotein hormones, alpha polypeptide multiple interactions
increases expression
ISO 2-(2-chloro-4-iodophenylamino)-N-cyclopropylmethoxy-3,4-difluorobenzamide inhibits the reaction [DDT results in increased expression of CGA mRNA]
DDT promotes the reaction [[CGA protein results in increased activity of FSHR protein] which results in increased abundance of Cyclic AMP]
CTD PMID:24814263, PMID:26895433 NCBI chr 5:50,362,491...50,393,368
Ensembl chr 5:50,381,244...50,393,367
JBrowse link
G Chrm4 cholinergic receptor, muscarinic 4 multiple interactions ISO [DDT co-treated with bioallethrin] results in increased expression of CHRM4 mRNA CTD PMID:10192214 NCBI chr 3:80,833,272...80,841,165
Ensembl chr 3:80,833,272...80,841,006
JBrowse link
G Clasp2 cytoplasmic linker associated protein 2 decreases methylation EXP DDT results in decreased methylation of CLASP2 gene CTD PMID:30207508 NCBI chr 8:122,003,719...122,185,495
Ensembl chr 8:122,003,916...122,185,495
JBrowse link
G Clip4 CAP-GLY domain containing linker protein family, member 4 increases methylation EXP DDT results in increased methylation of CLIP4 gene CTD PMID:30207508 NCBI chr 6:23,222,020...23,316,962
Ensembl chr 6:23,222,021...23,316,962
JBrowse link
G Clstn2 calsyntenin 2 decreases expression EXP DDT results in decreased expression of CLSTN2 mRNA CTD PMID:30207508 NCBI chr 8:105,322,577...106,036,821
Ensembl chr 8:105,323,837...105,462,168
JBrowse link
G Clu clusterin decreases expression EXP DDT results in decreased expression of CLU mRNA CTD PMID:30207508 NCBI chr15:42,626,612...42,665,858
Ensembl chr15:42,640,146...42,665,857
JBrowse link
G Cmc1 C-x(9)-C motif containing 1 increases methylation EXP DDT results in increased methylation of CMC1 gene CTD PMID:30207508 NCBI chr 8:126,437,345...126,495,347
Ensembl chr 8:126,437,345...126,495,347
JBrowse link
G Col11a1 collagen type XI alpha 1 chain decreases expression EXP DDT results in decreased expression of COL11A1 mRNA CTD PMID:30207508 NCBI chr 2:216,863,423...217,056,523
Ensembl chr 2:216,863,428...217,056,523
JBrowse link
G Col1a1 collagen type I alpha 1 chain increases expression ISO
EXP
DDT results in increased expression of COL1A1 mRNA CTD PMID:22902829, PMID:30207508 NCBI chr10:82,745,801...82,762,790
Ensembl chr10:82,745,801...82,762,789
JBrowse link
G Col3a1 collagen type III alpha 1 chain increases expression EXP DDT results in increased expression of COL3A1 mRNA CTD PMID:30207508 NCBI chr 9:52,023,295...52,059,221
Ensembl chr 9:52,023,295...52,059,217
JBrowse link
G Col4a1 collagen type IV alpha 1 chain increases expression EXP DDT results in increased expression of COL4A1 mRNA CTD PMID:30207508 NCBI chr16:83,522,162...83,632,153
Ensembl chr16:83,522,162...83,632,153
JBrowse link
G Col4a5 collagen type IV alpha 5 chain decreases expression EXP DDT results in decreased expression of COL4A5 mRNA CTD PMID:30207508 NCBI chr  X:112,769,595...112,983,720
Ensembl chr  X:112,769,645...112,983,685
JBrowse link
G Col6a1 collagen type VI alpha 1 chain increases expression EXP DDT results in increased expression of COL6A1 mRNA CTD PMID:30207508 NCBI chr20:12,657,913...12,676,370
Ensembl chr20:12,658,065...12,675,561
JBrowse link
G Col6a2 collagen type VI alpha 2 chain increases expression EXP DDT results in increased expression of COL6A2 mRNA CTD PMID:30207508 NCBI chr20:12,773,472...12,801,179
Ensembl chr20:12,773,427...12,801,180
JBrowse link
G Coq2 coenzyme Q2, polyprenyltransferase increases methylation EXP DDT results in increased methylation of COQ2 gene CTD PMID:30207508 NCBI chr14:10,581,102...10,601,093
Ensembl chr14:10,581,136...10,600,566
JBrowse link
G Coro6 coronin 6 increases expression ISO DDT results in increased expression of CORO6 mRNA CTD PMID:25014179 NCBI chr10:62,691,952...62,700,658
Ensembl chr10:62,691,953...62,699,723
JBrowse link
G Cpe carboxypeptidase E decreases expression EXP DDT results in decreased expression of CPE mRNA CTD PMID:30207508 NCBI chr16:26,906,716...27,014,811
Ensembl chr16:26,906,716...27,014,813
JBrowse link
G Creb1 cAMP responsive element binding protein 1 increases activity ISO DDT results in increased activity of CREB1 protein CTD PMID:18791200 NCBI chr 9:71,229,753...71,298,994
Ensembl chr 9:71,230,108...71,293,435
JBrowse link
G Creb3l1 cAMP responsive element binding protein 3-like 1 increases expression EXP DDT results in increased expression of CREB3L1 mRNA CTD PMID:30207508 NCBI chr 3:80,892,433...80,933,283
Ensembl chr 3:80,892,435...80,933,283
JBrowse link
G Crebbp CREB binding protein increases activity ISO DDT results in increased activity of CREBBP protein CTD PMID:22609851 NCBI chr10:11,590,994...11,721,039
Ensembl chr10:11,595,044...11,721,039
JBrowse link
G Crim1 cysteine rich transmembrane BMP regulator 1 decreases expression EXP DDT results in decreased expression of CRIM1 mRNA CTD PMID:30207508 NCBI chr 6:788,490...962,663
Ensembl chr 6:788,548...960,703
JBrowse link
G Csrnp3 cysteine and serine rich nuclear protein 3 increases methylation EXP DDT results in increased methylation of CSRNP3 gene CTD PMID:30207508 NCBI chr 3:51,883,559...52,120,290
Ensembl chr 3:51,883,559...52,120,290
JBrowse link
G Ctnna2 catenin alpha 2 decreases expression EXP DDT results in decreased expression of CTNNA2 mRNA CTD PMID:30207508 NCBI chr 4:107,880,611...109,042,724
Ensembl chr 4:107,881,826...108,008,484
JBrowse link
G Ctnna3 catenin alpha 3 decreases expression EXP DDT results in decreased expression of CTNNA3 mRNA CTD PMID:30207508 NCBI chr20:25,063,124...26,640,428
Ensembl chr20:26,516,836...26,589,209
JBrowse link
G Ctnnb1 catenin beta 1 multiple interactions
affects localization
increases expression
ISO Acetylcysteine inhibits the reaction [DDT results in increased expression of and results in decreased phosphorylation of CTNNB1 protein]; DDT inhibits the reaction [CDH1 protein binds to CTNNB1 protein]; DDT results in increased expression of and results in decreased phosphorylation of CTNNB1 protein
DDT affects the localization of CTNNB1 protein
DDT results in increased expression of CTNNB1 protein
CTD PMID:22902829, PMID:24968063 NCBI chr 8:129,601,511...129,628,378
Ensembl chr 8:129,617,812...129,627,372
JBrowse link
G Ctsd cathepsin D multiple interactions ISO [DDT results in increased activity of ESR1 protein] which results in increased expression of CTSD mRNA CTD PMID:22403704 NCBI chr 1:215,541,570...215,553,446
Ensembl chr 1:215,541,542...215,553,451
JBrowse link
G Cxcl12 C-X-C motif chemokine ligand 12 increases expression ISO DDT results in increased expression of CXCL12 mRNA CTD PMID:25014179 NCBI chr 4:149,261,044...149,273,891
Ensembl chr 4:149,261,044...149,273,891
JBrowse link
G Cyp11a1 cytochrome P450, family 11, subfamily a, polypeptide 1 increases expression ISO DDT results in increased expression of CYP11A1 mRNA CTD PMID:12858341 NCBI chr 8:62,798,317...62,809,848
Ensembl chr 8:62,779,875...62,809,893
JBrowse link
G Cyp17a1 cytochrome P450, family 17, subfamily a, polypeptide 1 increases expression
multiple interactions
ISO DDT results in increased expression of CYP17A1 mRNA
fulvestrant inhibits the reaction [DDT results in increased expression of CYP17A1 mRNA]
CTD PMID:23684557 NCBI chr 1:266,422,127...266,429,947
Ensembl chr 1:266,422,132...266,428,239
JBrowse link
G Cyp19a1 cytochrome P450, family 19, subfamily a, polypeptide 1 decreases expression
increases expression
increases activity
EXP
ISO
DDT results in decreased expression of CYP19A1 mRNA
DDT results in increased expression of CYP19A1 mRNA
DDT results in increased activity of CYP19A1 protein
CTD PMID:12035542, PMID:28263910, PMID:30817981 NCBI chr 8:58,744,849...58,772,408
Ensembl chr 8:58,744,849...58,772,408
JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 multiple interactions
decreases expression
increases expression
ISO
EXP
[indole-3-carbinol co-treated with DDT] results in increased expression of CYP1A1 mRNA; aurapten inhibits the reaction [DDT results in increased expression of CYP1A1 mRNA]; nobiletin inhibits the reaction [DDT results in increased expression of CYP1A1 mRNA]
DDT results in decreased expression of CYP1A1 mRNA
[Polychlorinated Biphenyls co-treated with DDT co-treated with Dichlorodiphenyl Dichloroethylene] results in increased expression of CYP1A1 mRNA
CTD PMID:16036770, PMID:17311112, PMID:20865247, PMID:28263910, PMID:29477483, PMID:31521043 NCBI chr 8:62,472,087...62,478,122
Ensembl chr 8:62,472,095...62,478,147
JBrowse link
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 increases expression EXP DDT results in increased expression of CYP1A2 mRNA CTD PMID:29477483 NCBI chr 8:62,451,360...62,458,244
Ensembl chr 8:62,451,329...62,458,301
JBrowse link
G Cyp1b1 cytochrome P450, family 1, subfamily b, polypeptide 1 multiple interactions ISO [indole-3-carbinol co-treated with DDT] results in increased expression of CYP1B1 mRNA CTD PMID:17311112 NCBI chr 6:2,308,179...2,316,739
Ensembl chr 6:2,307,808...2,316,722
JBrowse link
G Cyp2a1 cytochrome P450, family 2, subfamily a, polypeptide 1 increases expression EXP DDT results in increased expression of CYP2A1 mRNA CTD PMID:29477483 NCBI chr 1:83,711,223...83,725,222
Ensembl chr 1:83,653,234...83,766,484
JBrowse link
G Cyp2a2 cytochrome P450, family 2, subfamily a, polypeptide 2 increases expression EXP DDT results in increased expression of CYP2A2 mRNA CTD PMID:29477483 NCBI chr 1:83,744,229...83,766,490
Ensembl chr 1:83,653,234...83,766,484
JBrowse link
G Cyp2b1 cytochrome P450, family 2, subfamily b, polypeptide 1 multiple interactions
increases expression
increases activity
EXP
ISO
[DDT co-treated with Diethylnitrosamine] results in decreased expression of CYP2B1 mRNA; [DDT co-treated with Diethylnitrosamine] results in increased expression of CYP2B1 mRNA
DDT results in increased expression of CYP2B10 mRNA
[Androstanols co-treated with fulvestrant] inhibits the reaction [DDT results in increased expression of CYP2B10 mRNA]; Androstanols inhibits the reaction [DDT results in increased expression of CYP2B10 mRNA]; DDT promotes the reaction [GADD45B protein binds to CYP2B10 promoter]; DDT promotes the reaction [NR1I3 protein binds to CYP2B10 promoter]; DDT promotes the reaction [PPARGC1A protein binds to CYP2B10 promoter]
DDT results in increased activity of CYP2B1 protein
DDT results in increased expression of CYP2B1 protein
CTD PMID:1372805, PMID:7595932, PMID:11948501, PMID:12597452, PMID:15729006, PMID:15885732, PMID:23684557 NCBI chr 7:99,142,431...99,183,540
Ensembl chr 7:99,142,450...99,181,783
JBrowse link
G Cyp2b2 cytochrome P450, family 2, subfamily b, polypeptide 2 multiple interactions
increases expression
EXP [DDT co-treated with Diethylnitrosamine] results in decreased expression of CYP2B2 mRNA; [DDT co-treated with Diethylnitrosamine] results in increased expression of CYP2B2 mRNA
DDT results in increased expression of CYP2B2 protein
CTD PMID:7595932, PMID:15885732 NCBI chr 1:83,103,925...83,119,578
Ensembl chr 1:83,103,925...83,119,193
JBrowse link
G Cyp2b3 cytochrome P450, family 2, subfamily b, polypeptide 3 increases expression
decreases expression
multiple interactions
ISO
EXP
DDT results in increased expression of CYP2B6 mRNA; DDT results in increased expression of CYP2B6 protein
DDT results in decreased expression of CYP2B3 mRNA
[CYP2B6 gene SNP affects the susceptibility to DDT] which affects the abundance of Dichlorodiphenyl Dichloroethylene; CYP2B6 gene SNP affects the reaction [DDT results in increased abundance of Dichlorodiphenyl Dichloroethylene]
CTD PMID:15548381, PMID:20686338, PMID:27839851, PMID:29477483 NCBI chr 1:83,163,103...83,236,615
Ensembl chr 1:83,163,079...83,236,615
JBrowse link
G Cyp2d1 cytochrome P450, family 2, subfamily d, polypeptide 1 decreases expression EXP DDT results in decreased expression of CYP2D1 mRNA CTD PMID:29477483 NCBI chr 7:123,625,641...123,630,045
Ensembl chr 7:123,625,590...123,638,765
JBrowse link
G Cyp2t1 cytochrome P450, family 2, subfamily t, polypeptide 1 increases methylation EXP DDT results in increased methylation of CYP2T1 gene CTD PMID:30207508 NCBI chr 1:83,965,370...83,969,466
Ensembl chr 1:83,965,608...83,969,559
JBrowse link
G Cyp3a2 cytochrome P450, family 3, subfamily a, polypeptide 2 multiple interactions EXP [DDT co-treated with Diethylnitrosamine] results in decreased expression of CYP3A2 mRNA; [DDT co-treated with Diethylnitrosamine] results in increased expression of CYP3A2 mRNA CTD PMID:15885732 NCBI chr12:11,641,500...11,677,818
Ensembl chr12:11,655,402...11,733,136
JBrowse link
G Cyria CYFIP related Rac1 interactor A decreases expression EXP DDT results in decreased expression of CYRIA mRNA CTD PMID:30207508 NCBI chr 6:37,555,167...37,661,196
Ensembl chr 6:37,555,182...37,665,064
JBrowse link
G Dach1 dachshund family transcription factor 1 decreases expression EXP DDT results in decreased expression of DACH1 mRNA CTD PMID:30207508 NCBI chr15:82,095,003...82,482,272
Ensembl chr15:82,099,159...82,482,009
JBrowse link
G Dclre1c DNA cross-link repair 1C increases methylation EXP DDT results in increased methylation of DCLRE1C gene CTD PMID:30207508 NCBI chr17:78,782,512...78,812,140
Ensembl chr17:78,783,437...78,812,111
JBrowse link
G Def6 DEF6 guanine nucleotide exchange factor increases methylation EXP DDT results in increased methylation of DEF6 gene CTD PMID:30207508 NCBI chr20:7,788,120...7,809,011
Ensembl chr20:7,788,084...7,809,560
JBrowse link
G Des desmin increases expression EXP DDT results in increased expression of DES mRNA CTD PMID:30207508 NCBI chr 9:82,556,574...82,564,288
Ensembl chr 9:82,556,573...82,564,294
JBrowse link
G Dlx5 distal-less homeobox 5 increases expression ISO DDT results in increased expression of DLX5 mRNA CTD PMID:25014179 NCBI chr 4:32,387,741...32,392,085
Ensembl chr 4:32,387,741...32,392,007
JBrowse link
G Dmd dystrophin increases methylation EXP DDT results in increased methylation of DMD gene CTD PMID:30207508 NCBI chr  X:51,149,358...53,519,271
Ensembl chr  X:51,286,737...53,519,259
JBrowse link
G Dnajc15 DnaJ heat shock protein family (Hsp40) member C15 increases expression ISO DDT results in increased expression of DNAJC15 mRNA CTD PMID:25014179 NCBI chr15:59,990,131...60,056,710
Ensembl chr15:59,990,131...60,056,710
JBrowse link
G Dnmt1 DNA methyltransferase 1 decreases expression
increases expression
EXP DDT results in decreased expression of DNMT1 mRNA
DDT results in increased expression of DNMT1 mRNA; DDT results in increased expression of DNMT1 protein
CTD PMID:19797855, PMID:25410620 NCBI chr 8:21,922,515...21,968,495
Ensembl chr 8:21,922,515...21,968,495
JBrowse link
G Dnmt3a DNA methyltransferase 3 alpha decreases expression EXP DDT results in decreased expression of DNMT3A mRNA CTD PMID:19797855 NCBI chr 6:28,205,375...28,346,052
Ensembl chr 6:28,235,695...28,340,577
JBrowse link
G Dnmt3b DNA methyltransferase 3 beta decreases expression EXP DDT results in decreased expression of DNMT3B mRNA CTD PMID:19797855 NCBI chr 3:149,131,541...149,170,061
Ensembl chr 3:149,131,785...149,208,786
JBrowse link
G Dok5 docking protein 5 increases methylation EXP DDT results in increased methylation of DOK5 gene CTD PMID:30207508 NCBI chr 3:168,345,116...168,482,445
Ensembl chr 3:168,345,152...168,482,441
JBrowse link
G Dpy19l2 dpy-19 like 2 decreases methylation EXP DDT results in decreased methylation of DPY19L2 gene CTD PMID:30207508 NCBI chr 8:25,710,492...25,829,589
Ensembl chr 8:25,710,472...25,829,569
JBrowse link
G Dst dystonin increases methylation EXP DDT results in increased methylation of DST gene CTD PMID:30207508 NCBI chr 9:37,902,336...38,296,961
Ensembl chr 9:37,902,303...38,196,273
JBrowse link
G Dym dymeclin increases methylation EXP DDT results in increased methylation of DYM gene CTD PMID:30207508 NCBI chr18:70,996,074...71,313,033
Ensembl chr18:70,996,044...71,313,084
JBrowse link
G E2f1 E2F transcription factor 1 increases expression
multiple interactions
ISO DDT results in increased expression of E2F1 mRNA; DDT results in increased expression of E2F1 protein
fulvestrant inhibits the reaction [DDT results in increased expression of E2F1 mRNA]
CTD PMID:23684557 NCBI chr 3:150,062,895...150,073,721
Ensembl chr 3:150,047,826...150,073,721
JBrowse link
G Ebna1bp2 EBNA1 binding protein 2 increases expression EXP DDT results in increased expression of EBNA1BP2 mRNA CTD PMID:30207508 NCBI chr 5:137,458,692...137,463,255
Ensembl chr 5:137,670,123...137,674,802
JBrowse link
G Egf epidermal growth factor multiple interactions EXP [EGF protein co-treated with DDT] results in increased expression of MYC mRNA CTD PMID:12632255 NCBI chr 2:68,820,616...68,895,537 JBrowse link
G Egflam EGF-like, fibronectin type III and laminin G domains increases expression EXP DDT results in increased expression of EGFLAM mRNA CTD PMID:30207508 NCBI chr 2:56,503,002...56,681,334
Ensembl chr 2:56,502,807...56,679,955
JBrowse link
G Egln2 egl-9 family hypoxia-inducible factor 2 increases methylation EXP DDT results in increased methylation of EGLN2 gene CTD PMID:30207508 NCBI chr 1:83,969,456...83,977,665
Ensembl chr 1:83,969,457...83,977,236
JBrowse link
G Egr1 early growth response 1 decreases expression
increases expression
ISO
EXP
DDT results in decreased expression of EGR1 mRNA
DDT results in increased expression of EGR1 mRNA
CTD PMID:25014179, PMID:30207508 NCBI chr18:27,657,903...27,660,101
Ensembl chr18:27,657,628...27,661,429
JBrowse link
G Egr2 early growth response 2 increases expression EXP DDT results in increased expression of EGR2 mRNA CTD PMID:30207508 NCBI chr20:22,452,170...22,461,018
Ensembl chr20:22,454,463...22,459,025
JBrowse link
G Eif4a2 eukaryotic translation initiation factor 4A2 increases expression ISO DDT results in increased expression of EIF4A2 mRNA CTD PMID:25014179 NCBI chr11:81,373,047...81,379,680
Ensembl chr11:81,373,048...81,379,871
JBrowse link
G Elk1 ETS transcription factor ELK1 increases activity ISO DDT results in increased activity of ELK1 protein CTD PMID:18791200 NCBI chr  X:1,287,875...1,304,822
Ensembl chr  X:1,297,099...1,304,822
JBrowse link
G Emilin2 elastin microfibril interfacer 2 increases expression EXP DDT results in increased expression of EMILIN2 mRNA CTD PMID:30207508 NCBI chr 9:119,594,049...119,653,675
Ensembl chr 9:119,594,629...119,653,255
JBrowse link
G Enc1 ectodermal-neural cortex 1 decreases expression
increases expression
EXP DDT results in decreased expression of ENC1 mRNA
DDT results in increased expression of ENC1 mRNA
CTD PMID:19797855, PMID:30207508 NCBI chr 2:28,049,217...28,061,023
Ensembl chr 2:28,049,217...28,061,029
JBrowse link
G Eno1 enolase 1 decreases expression ISO DDT results in decreased expression of ENO1 protein CTD PMID:26186133 NCBI chr 5:167,288,223...167,299,610
Ensembl chr 5:167,288,223...167,299,609
JBrowse link
G Enpp3 ectonucleotide pyrophosphatase/phosphodiesterase 3 decreases methylation EXP DDT results in decreased methylation of ENPP3 gene CTD PMID:30207508 NCBI chr 1:21,613,148...21,684,483
Ensembl chr 1:21,613,148...21,684,480
JBrowse link
G Epas1 endothelial PAS domain protein 1 decreases expression EXP DDT results in decreased expression of EPAS1 mRNA CTD PMID:30207508 NCBI chr 6:10,306,508...10,385,239
Ensembl chr 6:10,306,405...10,387,265
JBrowse link
G Epha3 Eph receptor A3 multiple interactions ISO [Hexachlorocyclohexane co-treated with Aldrin co-treated with Dieldrin co-treated with Endrin co-treated with Dichlorodiphenyl Dichloroethylene co-treated with Dichlorodiphenyldichloroethane co-treated with DDT co-treated with Simvastatin] results in increased expression of EPHA3 mRNA CTD PMID:28263720 NCBI chr11:421,253...783,037
Ensembl chr11:421,135...782,954
JBrowse link
G Epha8 Eph receptor A8 multiple interactions ISO [Hexachlorocyclohexane co-treated with Aldrin co-treated with Dieldrin co-treated with Endrin co-treated with Dichlorodiphenyl Dichloroethylene co-treated with Dichlorodiphenyldichloroethane co-treated with DDT co-treated with Simvastatin] results in increased expression of EPHA8 mRNA CTD PMID:28263720 NCBI chr 5:155,293,731...155,321,016
Ensembl chr 5:155,295,314...155,316,495
JBrowse link
G Ephx1 epoxide hydrolase 1 increases activity EXP DDT results in increased activity of EPHX1 protein CTD PMID:1372805 NCBI chr13:99,271,390...99,300,580
Ensembl chr13:99,271,366...99,300,579
JBrowse link
G Erbb2 erb-b2 receptor tyrosine kinase 2 increases phosphorylation ISO DDT results in increased phosphorylation of ERBB2 protein CTD PMID:9070211 NCBI chr10:86,367,596...86,391,728
Ensembl chr10:86,367,596...86,391,728
JBrowse link
G Esd esterase D increases expression EXP DDT results in increased expression of ESD mRNA CTD PMID:29477483 NCBI chr15:56,756,848...56,776,348
Ensembl chr15:56,756,661...56,776,348
JBrowse link
G Esr1 estrogen receptor 1 multiple interactions
increases expression
decreases expression
increases methylation
increases activity
affects binding
ISO
EXP
[DDT analog co-treated with Hexachlorocyclohexane analog co-treated with Chlorobenzenes co-treated with Mirex co-treated with Polychlorinated Biphenyls co-treated with Chlordan co-treated with Toxaphene co-treated with Aldrin co-treated with Dieldrin] results in increased expression of ESR1 mRNA; [DDT results in increased activity of ESR1 protein] which results in decreased expression of GABRP mRNA; [DDT results in increased activity of ESR1 protein] which results in decreased expression of GSN mRNA; [DDT results in increased activity of ESR1 protein] which results in increased expression of BCL2 mRNA; [DDT results in increased activity of ESR1 protein] which results in increased expression of CTSD mRNA; [DDT results in increased activity of ESR1 protein] which results in increased expression of PGR mRNA; [DDT results in increased activity of ESR1 protein] which results in increased expression of SERPINB5 mRNA; [DDT results in increased activity of ESR1 protein] which results in increased expression of TFF1 mRNA; [Hexachlorocyclohexane co-treated with DDT] results in increased expression of ESR1; DDT binds to and results in increased activity of ESR1 protein
DDT results in increased expression of ESR1 mRNA
DDT results in decreased expression of ESR1 protein
DDT results in increased methylation of ESR1 gene
DDT promotes the reaction [ESR1 protein binds to CCND1 promoter]; DDT promotes the reaction [ESR1 protein binds to CDKN1A promoter]
[o,p'-DDT co-treated with Dichlorodiphenyl Dichloroethylene co-treated with Methoxychlor co-treated with Endosulfan co-treated with DDT] results in increased activity of ESR1 protein
DDT binds to ESR1 protein
DDT results in increased expression of ESR1 mRNA; DDT results in increased expression of ESR1 protein
CTD PMID:9860891, PMID:11485867, PMID:12676605, PMID:15026083, PMID:15064155, PMID:15541753, PMID:16329587, PMID:16626760, PMID:18801367, PMID:19913605, PMID:21295777, PMID:22403704, PMID:23684557, PMID:25014179, PMID:26022396, PMID:26139245, PMID:26812056, PMID:28263910, PMID:29477483 NCBI chr 1:41,192,029...41,594,799
Ensembl chr 1:41,192,824...41,594,796
JBrowse link
G Esr2 estrogen receptor 2 multiple interactions
increases activity
ISO
EXP
DDT binds to and results in increased activity of ESR2 protein
DDT results in increased activity of ESR2 protein
[o,p'-DDT co-treated with Dichlorodiphenyl Dichloroethylene co-treated with Methoxychlor co-treated with Endosulfan co-treated with DDT] results in increased activity of ESR2 protein
CTD PMID:9860891, PMID:15064155, PMID:16626760, PMID:26139245, PMID:26812056 NCBI chr 6:99,163,953...99,214,711
Ensembl chr 6:99,164,357...99,214,251
JBrowse link
G Esrp1 epithelial splicing regulatory protein 1 increases methylation EXP DDT results in increased methylation of ESRP1 gene CTD PMID:30207508 NCBI chr 5:24,576,988...24,631,758
Ensembl chr 5:24,576,991...24,631,698
JBrowse link
G Fabp4 fatty acid binding protein 4 increases expression ISO DDT results in increased expression of FABP4 mRNA CTD PMID:25014179 NCBI chr 2:93,792,666...93,797,267
Ensembl chr 2:93,792,601...93,797,305
JBrowse link
G Fam102a family with sequence similarity 102, member A increases expression ISO DDT results in increased expression of FAM102A mRNA CTD PMID:14605097 NCBI chr 3:11,554,084...11,586,315
Ensembl chr 3:11,554,457...11,586,303
JBrowse link
G Fam171b family with sequence similarity 171, member B decreases expression EXP DDT results in decreased expression of FAM171B mRNA CTD PMID:30207508 NCBI chr 3:71,210,048...71,265,419
Ensembl chr 3:71,210,301...71,262,615
JBrowse link
G Fam174a family with sequence similarity 174, member A increases methylation EXP DDT results in increased methylation of FAM174A gene CTD PMID:30207508 NCBI chr 9:102,862,761...102,881,046
Ensembl chr 9:102,862,890...102,881,038
JBrowse link
G Fam50a family with sequence similarity 50, member A decreases expression EXP DDT results in decreased expression of FAM50A mRNA CTD PMID:30207508 NCBI chr  X:156,392,646...156,399,763
Ensembl chr  X:156,392,630...156,399,760
JBrowse link
G Fan1 FANCD2 and FANCI associated nuclease 1 increases methylation EXP DDT results in increased methylation of FAN1 gene CTD PMID:30207508 NCBI chr 1:125,182,117...125,209,772
Ensembl chr 1:125,181,838...125,209,727
JBrowse link
G Fap fibroblast activation protein, alpha increases methylation EXP DDT results in increased methylation of FAP gene CTD PMID:30207508 NCBI chr 3:48,467,781...48,536,242
Ensembl chr 3:48,467,781...48,536,235
JBrowse link
G Faslg Fas ligand increases expression EXP DDT results in increased expression of FASLG mRNA CTD PMID:29477483 NCBI chr13:79,696,811...79,717,581
Ensembl chr13:79,698,445...79,705,705
JBrowse link
G Fasn fatty acid synthase decreases expression EXP DDT results in decreased expression of FASN mRNA CTD PMID:29477483 NCBI chr10:109,987,735...110,005,901
Ensembl chr10:109,987,735...110,005,901
JBrowse link
G Fbxo32 F-box protein 32 decreases expression EXP DDT results in decreased expression of FBXO32 mRNA CTD PMID:30207508 NCBI chr 7:98,065,664...98,098,071
Ensembl chr 7:98,063,735...98,098,268
JBrowse link
G Fgd3 FYVE, RhoGEF and PH domain containing 3 increases methylation EXP DDT results in increased methylation of FGD3 gene CTD PMID:30207508 NCBI chr17:15,737,962...15,800,403
Ensembl chr17:15,749,978...15,800,401
JBrowse link
G Fgf2 fibroblast growth factor 2 decreases expression ISO DDT results in decreased expression of FGF2 mRNA CTD PMID:31521043 NCBI chr 2:124,081,072...124,134,133
Ensembl chr 2:124,081,072...124,134,681
JBrowse link
G Fgl2 fibrinogen-like 2 decreases expression EXP DDT results in decreased expression of FGL2 mRNA CTD PMID:30207508 NCBI chr 4:10,323,598...10,329,241
Ensembl chr 4:10,323,607...10,329,241
JBrowse link
G Filip1l filamin A interacting protein 1-like decreases expression EXP DDT results in decreased expression of FILIP1L mRNA CTD PMID:30207508 NCBI chr11:45,039,488...45,275,141
Ensembl chr11:45,039,461...45,124,423
JBrowse link
G Fn1 fibronectin 1 increases expression ISO DDT results in increased expression of FN1 protein CTD PMID:22902829 NCBI chr 9:78,900,111...78,969,018
Ensembl chr 9:78,900,103...78,969,078
JBrowse link
G Folh1 folate hydrolase 1 multiple interactions
increases expression
ISO DDT inhibits the reaction [Metribolone results in decreased expression of FOLH1 mRNA]; DDT inhibits the reaction [Metribolone results in decreased expression of FOLH1 protein]
DDT results in increased expression of FOLH1 protein
CTD PMID:25682698 NCBI chr 1:150,323,768...150,395,415
Ensembl chr 1:150,323,768...150,395,415
JBrowse link
G Fos Fos proto-oncogene, AP-1 transcription factor subunit increases activity
increases expression
multiple interactions
ISO
EXP
DDT results in increased activity of FOS protein
DDT results in increased expression of FOS mRNA
[Permethrin co-treated with DDT co-treated with Diethylstilbestrol] inhibits the reaction [Potassium results in increased expression of FOS mRNA]; DDT inhibits the reaction [Potassium results in increased expression of FOS mRNA]; DDT promotes the reaction [FOS protein binds to CCND1 promoter]; fulvestrant inhibits the reaction [DDT results in increased expression of FOS mRNA]
CTD PMID:14604893, PMID:15527870, PMID:23684557, PMID:25014179, PMID:28263910, PMID:30207508 NCBI chr 6:109,300,433...109,303,299
Ensembl chr 6:109,300,433...109,303,299
JBrowse link
G Fosb FosB proto-oncogene, AP-1 transcription factor subunit increases expression EXP DDT results in increased expression of FOSB mRNA CTD PMID:30207508 NCBI chr 1:80,214,691...80,221,417
Ensembl chr 1:80,214,494...80,221,710
JBrowse link
G Fosl1 FOS like 1, AP-1 transcription factor subunit increases expression ISO DDT results in increased expression of FOSL1 mRNA CTD PMID:18791200 NCBI chr 1:220,826,560...220,835,066
Ensembl chr 1:220,826,560...220,835,066
JBrowse link
G Foxp2 forkhead box P2 decreases expression EXP DDT results in decreased expression of FOXP2 mRNA CTD PMID:30207508 NCBI chr 4:41,364,441...41,944,685
Ensembl chr 4:41,364,441...41,942,023
JBrowse link
G Frmd3 FERM domain containing 3 decreases expression EXP DDT results in decreased expression of FRMD3 mRNA CTD PMID:30207508 NCBI chr 5:90,040,495...90,282,327
Ensembl chr 5:90,040,495...90,282,327
JBrowse link
G Fryl FRY like transcription coactivator increases methylation EXP DDT results in increased methylation of FRYL gene CTD PMID:30207508 NCBI chr14:37,551,109...37,757,511
Ensembl chr14:37,551,940...37,756,149
JBrowse link
G Fshb follicle stimulating hormone subunit beta multiple interactions
increases expression
EXP
ISO
DDT inhibits the reaction [FSHB protein binds to FSHR protein]
DDT promotes the reaction [[FSHB protein results in increased activity of FSHR protein] which results in increased abundance of Cyclic AMP]
DDT results in increased expression of FSHB mRNA; DDT results in increased expression of FSHB protein
2-(2-chloro-4-iodophenylamino)-N-cyclopropylmethoxy-3,4-difluorobenzamide inhibits the reaction [DDT results in increased expression of FSHB mRNA]
CTD PMID:17157474, PMID:24814263, PMID:26895433 NCBI chr 3:98,088,321...98,092,131
Ensembl chr 3:98,088,324...98,092,131
JBrowse link
G Fshr follicle stimulating hormone receptor affects activity
decreases activity
multiple interactions
EXP
ISO
DDT affects the activity of FSHR protein
DDT results in decreased activity of FSHR protein
DDT promotes the reaction [[CGA protein results in increased activity of FSHR protein] which results in increased abundance of Cyclic AMP]; DDT promotes the reaction [[FSHB protein results in increased activity of FSHR protein] which results in increased abundance of Cyclic AMP]
DDT inhibits the reaction [FSHB protein binds to FSHR protein]
CTD PMID:17157474, PMID:26895433 NCBI chr 6:12,796,383...12,997,817
Ensembl chr 6:12,796,383...12,997,817
JBrowse link
G G6pd glucose-6-phosphate dehydrogenase increases activity
multiple interactions
EXP DDT results in increased activity of G6PD protein
Inositol inhibits the reaction [DDT results in increased activity of G6PD protein]
CTD PMID:12667599 NCBI chr  X:156,274,800...156,293,935
Ensembl chr  X:156,274,800...156,293,926
JBrowse link
G Gabbr2 gamma-aminobutyric acid type B receptor subunit 2 decreases expression EXP DDT results in decreased expression of GABBR2 mRNA CTD PMID:19797855 NCBI chr 5:62,276,100...62,621,737
Ensembl chr 5:62,276,100...62,621,737
JBrowse link
G Gabrg3 gamma-aminobutyric acid type A receptor subunit gamma 3 decreases methylation EXP DDT results in decreased methylation of GABRG3 gene CTD PMID:30207508 NCBI chr 1:112,158,525...112,812,267
Ensembl chr 1:112,158,519...112,811,936
JBrowse link
G Gabrp gamma-aminobutyric acid type A receptor subunit pi multiple interactions ISO [DDT results in increased activity of ESR1 protein] which results in decreased expression of GABRP mRNA CTD PMID:22403704 NCBI chr10:18,484,257...18,510,604
Ensembl chr10:18,485,514...18,506,337
JBrowse link
G Gadd45b growth arrest and DNA-damage-inducible, beta multiple interactions
increases expression
ISO Androstanols inhibits the reaction [DDT results in increased expression of GADD45B mRNA]; DDT promotes the reaction [GADD45B protein binds to CYP2B10 promoter]
DDT results in increased expression of GADD45B mRNA; DDT results in increased expression of GADD45B protein
CTD PMID:23684557 NCBI chr 7:11,646,283...11,648,338
Ensembl chr 7:11,646,269...11,648,322
JBrowse link
G Gal galanin and GMAP prepropeptide decreases expression EXP DDT results in decreased expression of GAL mRNA CTD PMID:19797855 NCBI chr 1:218,653,059...218,657,922
Ensembl chr 1:218,652,917...218,657,925
JBrowse link
G Gas5 growth arrest specific 5 decreases expression ISO DDT results in decreased expression of GAS5 mRNA CTD PMID:25014179 NCBI chr13:78,852,523...78,855,844 JBrowse link
G Gcc2 GRIP and coiled-coil domain containing 2 decreases expression EXP DDT results in decreased expression of GCC2 mRNA CTD PMID:30207508 NCBI chr20:27,832,960...27,879,764
Ensembl chr20:27,832,932...27,879,759
JBrowse link
G Gclc glutamate-cysteine ligase, catalytic subunit increases expression ISO
EXP
DDT results in increased expression of GCLC mRNA CTD PMID:26198647, PMID:29477483 NCBI chr 8:85,059,051...85,097,471
Ensembl chr 8:85,059,051...85,097,468
JBrowse link
G Gclm glutamate cysteine ligase, modifier subunit increases expression ISO DDT results in increased expression of GCLM mRNA CTD PMID:26198647 NCBI chr 2:225,827,504...225,847,876
Ensembl chr 2:225,827,504...225,847,874
JBrowse link
G Gcnt4 glucosaminyl (N-acetyl) transferase 4 increases methylation EXP DDT results in increased methylation of GCNT4 gene CTD PMID:30207508 Ensembl chr 2:27,713,880...27,780,119 JBrowse link
G Gfra1 GDNF family receptor alpha 1 multiple interactions ISO [Hexachlorocyclohexane co-treated with Aldrin co-treated with Dieldrin co-treated with Endrin co-treated with Dichlorodiphenyl Dichloroethylene co-treated with Dichlorodiphenyldichloroethane co-treated with DDT co-treated with Simvastatin] results in decreased expression of GFRA1 mRNA CTD PMID:28263720 NCBI chr 1:279,203,046...279,572,789 JBrowse link
G Ggt1 gamma-glutamyltransferase 1 decreases activity
increases activity
EXP DDT results in decreased activity of GGT1 protein
DDT results in increased activity of GGT1 protein
CTD PMID:2387028, PMID:9475050 NCBI chr20:14,019,723...14,045,781
Ensembl chr20:14,019,723...14,025,068
JBrowse link
G Ghr growth hormone receptor decreases expression EXP DDT results in decreased expression of GHR mRNA CTD PMID:30207508 NCBI chr 2:53,149,225...53,413,954
Ensembl chr 2:53,150,370...53,413,638
JBrowse link
G Gja1 gap junction protein, alpha 1 multiple interactions
increases degradation
decreases expression
ISO
EXP
[DDT co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl] results in decreased expression of GJA1 protein
DDT results in increased degradation of GJA1 protein; DDT results in increased degradation of GJA1 protein modified form
Chloroquine inhibits the reaction [DDT results in increased degradation of GJA1 protein modified form]; Colchicine inhibits the reaction [DDT results in increased degradation of GJA1 protein modified form]; DDT results in decreased expression of and results in increased phosphorylation of GJA1 protein
DDT results in decreased expression of GJA1 protein; DDT results in decreased expression of GJA1 protein modified form
CTD PMID:8285856, PMID:8313522, PMID:8820588, PMID:8824497, PMID:15082077 NCBI chr20:37,876,650...37,889,097
Ensembl chr20:37,876,650...37,889,089
JBrowse link
G Gjb1 gap junction protein, beta 1 multiple interactions
decreases expression
EXP [DDT co-treated with Diethylnitrosamine] results in decreased expression of GJB1 mRNA; [DDT co-treated with Diethylnitrosamine] results in increased expression of GJB1 mRNA
DDT results in decreased expression of GJB1 protein
CTD PMID:8242434, PMID:15885732 NCBI chr  X:71,272,030...71,279,973
Ensembl chr  X:71,272,042...71,279,977
JBrowse link
G Gnrh1 gonadotropin releasing hormone 1 multiple interactions ISO [Hexachlorocyclohexane co-treated with DDT] results in increased expression of GNRH1 CTD PMID:16329587 NCBI chr15:44,441,856...44,446,064
Ensembl chr15:44,442,555...44,442,875
Ensembl chr15:44,442,555...44,442,875
JBrowse link
G Golgb1 golgin B1 decreases expression EXP DDT results in decreased expression of GOLGB1 mRNA CTD PMID:30207508 NCBI chr11:66,761,646...66,819,115
Ensembl chr11:66,761,584...66,819,079
JBrowse link
G Golim4 golgi integral membrane protein 4 decreases expression EXP DDT results in decreased expression of GOLIM4 mRNA CTD PMID:30207508 NCBI chr 2:174,321,303...174,413,847
Ensembl chr 2:174,322,673...174,413,236
JBrowse link
G Gpat3 glycerol-3-phosphate acyltransferase 3 increases expression ISO DDT results in increased expression of GPAT3 mRNA CTD PMID:26198647 NCBI chr14:10,343,287...10,396,565
Ensembl chr14:10,343,282...10,395,047
JBrowse link
G Gpc3 glypican 3 increases expression EXP DDT results in increased expression of GPC3 mRNA CTD PMID:30207508 NCBI chr  X:139,579,268...139,947,093
Ensembl chr  X:139,579,268...139,916,883
JBrowse link
G Gper1 G protein-coupled estrogen receptor 1 affects binding
affects expression
decreases expression
increases methylation
ISO DDT binds to GPER1 protein
DDT affects the expression of GPER1 mRNA
DDT results in decreased expression of GPER1 protein
DDT results in increased methylation of GPER1 gene
CTD PMID:17088055, PMID:28263910 NCBI chr12:17,309,122...17,315,267
Ensembl chr12:17,309,834...17,311,112
JBrowse link
G Gpnmb glycoprotein nmb increases methylation EXP DDT results in increased methylation of GPNMB gene CTD PMID:30207508 NCBI chr 4:78,694,447...78,715,685
Ensembl chr 4:78,694,447...78,715,683
JBrowse link
G Gpt glutamic--pyruvic transaminase increases activity EXP DDT results in increased activity of GPT protein CTD PMID:2387028 NCBI chr 7:117,759,083...117,761,932
Ensembl chr 7:117,759,083...117,761,931
JBrowse link
G Grb2 growth factor receptor bound protein 2 multiple interactions ISO DDT promotes the reaction [GRB2 protein binds to SOS1 protein] CTD PMID:9070211 NCBI chr10:104,193,953...104,263,071
Ensembl chr10:104,193,955...104,263,071
JBrowse link
G Grifin galectin-related inter-fiber protein increases expression EXP DDT results in increased expression of GRIFIN mRNA CTD PMID:19797855 NCBI chr12:16,170,108...16,172,144
Ensembl chr12:16,170,162...16,172,129
JBrowse link
G Grm1 glutamate metabotropic receptor 1 decreases methylation EXP DDT results in decreased methylation of GRM1 gene CTD PMID:30207508 NCBI chr 1:4,753,141...5,165,859
Ensembl chr 1:4,753,144...5,165,859
JBrowse link
G Gsk3b glycogen synthase kinase 3 beta increases phosphorylation
multiple interactions
ISO DDT results in increased phosphorylation of GSK3B protein
Acetylcysteine inhibits the reaction [DDT results in increased phosphorylation of GSK3B protein]
CTD PMID:24968063 NCBI chr11:65,060,884...65,208,842
Ensembl chr11:65,066,235...65,209,268
JBrowse link
G Gsn gelsolin multiple interactions ISO [DDT results in increased activity of ESR1 protein] which results in decreased expression of GSN mRNA CTD PMID:22403704 NCBI chr 3:14,456,106...14,508,922
Ensembl chr 3:14,467,330...14,508,911
JBrowse link
G Gsta1 glutathione S-transferase alpha 1 increases expression EXP DDT results in increased expression of GSTA1 mRNA CTD PMID:30207508 NCBI chr 9:27,366,404...27,381,004
Ensembl chr 9:27,368,272...27,452,902
JBrowse link
G Gsta2 glutathione S-transferase alpha 2 increases expression EXP DDT results in increased expression of GSTA2 mRNA CTD PMID:29477483 NCBI chr 8:85,640,081...85,645,621 JBrowse link
G Gsto1 glutathione S-transferase omega 1 increases expression ISO DDT results in increased expression of GSTO1 mRNA CTD PMID:31521043 NCBI chr 1:267,607,437...267,617,387
Ensembl chr 1:267,607,418...267,617,387
JBrowse link
G Herpud2 HERPUD family member 2 increases methylation EXP DDT results in increased methylation of HERPUD2 gene CTD PMID:30207508 NCBI chr 8:26,266,571...26,311,528
Ensembl chr 8:26,266,760...26,311,350
JBrowse link
G Hgf hepatocyte growth factor decreases expression ISO DDT results in decreased expression of HGF mRNA CTD PMID:25014179 NCBI chr 4:15,435,460...15,505,377
Ensembl chr 4:15,433,295...15,505,362
JBrowse link
G Hipk3 homeodomain interacting protein kinase 3 increases methylation EXP DDT results in increased methylation of HIPK3 gene CTD PMID:30207508 NCBI chr 3:94,349,778...94,419,185
Ensembl chr 3:94,352,969...94,419,048
JBrowse link
G Hmox1 heme oxygenase 1 increases expression ISO DDT results in increased expression of HMOX1 mRNA CTD PMID:31521043 NCBI chr19:14,508,634...14,515,455
Ensembl chr19:14,508,616...14,515,456
JBrowse link
G Hnf1a HNF1 homeobox A multiple interactions EXP [DDT co-treated with Diethylnitrosamine] results in decreased expression of HNF1A mRNA; [DDT co-treated with Diethylnitrosamine] results in increased expression of HNF1A mRNA CTD PMID:15885732 NCBI chr12:47,407,811...47,433,342
Ensembl chr12:47,407,811...47,433,342
JBrowse link
G Hook3 hook microtubule-tethering protein 3 decreases expression EXP DDT results in decreased expression of HOOK3 mRNA CTD PMID:30207508 NCBI chr16:70,710,347...70,818,789 JBrowse link
G Hs3st2 heparan sulfate-glucosamine 3-sulfotransferase 2 decreases methylation EXP DDT results in decreased methylation of HS3ST2 gene CTD PMID:30207508 NCBI chr 1:191,344,979...191,474,143
Ensembl chr 1:191,344,979...191,474,142
JBrowse link
G Hsd17b1 hydroxysteroid (17-beta) dehydrogenase 1 decreases expression
multiple interactions
ISO DDT results in decreased expression of HSD17B1 mRNA
MT2A protein inhibits the reaction [DDT results in decreased expression of HSD17B1 mRNA]
CTD PMID:12858341 NCBI chr10:88,987,558...88,989,758
Ensembl chr10:88,987,558...88,989,757
JBrowse link
G Hsd3b1 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1 increases expression ISO DDT results in increased expression of HSD3B1 mRNA CTD PMID:12858341
G Hsp90ab1 heat shock protein 90 alpha family class B member 1 decreases expression EXP DDT results in decreased expression of HSP90AB1 mRNA CTD PMID:19797855 NCBI chr 9:17,817,791...17,823,163
Ensembl chr 9:17,817,721...17,823,243
JBrowse link
G Hspa4 heat shock protein family A (Hsp70) member 4 decreases expression EXP DDT results in decreased expression of HSPA4 mRNA CTD PMID:19797855 NCBI chr10:38,601,624...38,642,397
Ensembl chr10:38,601,624...38,642,397
JBrowse link
G Hspa5 heat shock protein family A (Hsp70) member 5 increases expression ISO
EXP
DDT results in increased expression of HSPA5 mRNA CTD PMID:15710169, PMID:29477483 NCBI chr 3:13,838,304...13,842,763
Ensembl chr 3:13,838,304...13,842,762
JBrowse link
G Htr1a 5-hydroxytryptamine receptor 1A decreases expression ISO DDT results in decreased expression of HTR1A mRNA CTD PMID:28263910 NCBI chr 2:36,246,628...36,247,896
Ensembl chr 2:36,246,628...36,247,896
JBrowse link
G Ibsp integrin-binding sialoprotein increases methylation EXP DDT results in increased methylation of IBSP gene CTD PMID:30207508 NCBI chr14:6,801,200...6,813,987
Ensembl chr14:6,801,204...6,813,945
JBrowse link
G Ide insulin degrading enzyme decreases activity ISO DDT results in decreased activity of IDE protein CTD PMID:25720399 NCBI chr 1:255,914,465...256,014,168
Ensembl chr 1:255,914,447...256,013,495
JBrowse link
G Ifit2 interferon-induced protein with tetratricopeptide repeats 2 decreases expression ISO DDT results in decreased expression of IFIT2 mRNA CTD PMID:25014179 NCBI chr 1:252,894,663...252,900,727
Ensembl chr 1:252,894,663...252,900,726
JBrowse link
G Igf1 insulin-like growth factor 1 multiple interactions
decreases expression
increases methylation
ISO
EXP
DDT affects the reaction [Metribolone results in increased expression of IGF1 mRNA]
DDT results in decreased expression of IGF1 mRNA
DDT results in increased methylation of IGF1 gene
CTD PMID:25682698, PMID:30207508, PMID:30822522 NCBI chr 7:28,412,123...28,491,815
Ensembl chr 7:28,412,198...28,486,609
JBrowse link
G Igf2 insulin-like growth factor 2 decreases expression EXP DDT results in decreased expression of IGF2 mRNA CTD PMID:19797855 NCBI chr 1:215,828,102...215,839,081
Ensembl chr 1:215,828,102...215,846,911
JBrowse link
G Il1b interleukin 1 beta decreases expression
increases secretion
multiple interactions
ISO DDT metabolite results in decreased expression of IL1B mRNA; DDT results in decreased expression of IL1B mRNA
DDT results in increased secretion of IL1B protein
[DDT co-treated with o,p'-DDT] results in decreased expression of IL1B mRNA
CTD PMID:12007859, PMID:27592000 NCBI chr 3:121,876,256...121,882,637
Ensembl chr 3:121,876,263...121,882,726
JBrowse link
G Il1r1 interleukin 1 receptor type 1 increases expression
decreases expression
EXP DDT results in increased expression of IL1R1 mRNA
DDT results in decreased expression of IL1R1 mRNA
CTD PMID:11948501 NCBI chr 9:46,962,291...47,038,139
Ensembl chr 9:46,962,288...47,036,670
JBrowse link
G Il2 interleukin 2 decreases expression ISO DDT results in decreased expression of IL2 mRNA; DDT results in decreased expression of IL2 protein CTD PMID:16696175 NCBI chr 2:123,847,150...123,851,854
Ensembl chr 2:123,847,150...123,851,854
JBrowse link
G Il4 interleukin 4 multiple interactions ISO [DDT co-treated with Dichlorodiphenyl Dichloroethylene] results in increased expression of IL4 protein CTD PMID:12696651 NCBI chr10:38,963,979...38,969,531
Ensembl chr10:38,963,979...38,969,531
JBrowse link
G Il6 interleukin 6 decreases expression
multiple interactions
increases expression
EXP
ISO
DDT results in decreased expression of IL6 mRNA
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [DDT results in increased expression of and results in increased secretion of IL6 protein]; DDT results in increased expression of and results in increased secretion of IL6 protein
DDT results in increased expression of IL6 mRNA
CTD PMID:29477483, PMID:31542660 NCBI chr 4:3,043,231...3,047,807
Ensembl chr 4:3,043,231...3,047,807
JBrowse link
G Inhbc inhibin subunit beta C decreases methylation EXP DDT results in decreased methylation of INHBC gene CTD PMID:30207508 NCBI chr 7:70,648,005...70,661,475
Ensembl chr 7:70,646,519...70,661,891
JBrowse link
G Insr insulin receptor decreases methylation EXP DDT results in decreased methylation of INSR gene CTD PMID:30207508 NCBI chr12:1,682,527...1,816,414
Ensembl chr12:1,680,957...1,816,414
JBrowse link
G Itga5 integrin subunit alpha 5 increases expression ISO DDT results in increased expression of ITGA5 mRNA CTD PMID:22902829 NCBI chr 7:144,970,444...144,993,652
Ensembl chr 7:144,970,444...144,993,652
JBrowse link
G Itga9 integrin subunit alpha 9 increases expression EXP DDT results in increased expression of ITGA9 mRNA CTD PMID:30207508 NCBI chr 8:127,271,029...127,576,709
Ensembl chr 8:127,271,289...127,572,988
JBrowse link
G Itgb1 integrin subunit beta 1 multiple interactions
increases expression
ISO Acetylcysteine inhibits the reaction [DDT results in increased expression of ITGB1 mRNA]; INCB018424 inhibits the reaction [DDT results in increased expression of ITGB1 mRNA]; WP1066 inhibits the reaction [DDT results in increased expression of ITGB1 mRNA] CTD PMID:24820114 NCBI chr19:61,677,512...61,725,537
Ensembl chr19:61,677,542...61,725,535
JBrowse link
G Jak1 Janus kinase 1 multiple interactions
increases phosphorylation
ISO Acetylcysteine inhibits the reaction [DDT results in increased phosphorylation of JAK1 protein]; INCB018424 inhibits the reaction [DDT results in increased phosphorylation of JAK1 protein] CTD PMID:24820114 NCBI chr 5:119,982,503...120,091,452
Ensembl chr 5:119,982,943...120,083,904
JBrowse link
G Jun Jun proto-oncogene, AP-1 transcription factor subunit increases activity
increases expression
ISO DDT results in increased activity of JUN protein
DDT results in increased expression of JUN protein
CTD PMID:14604893 NCBI chr 5:114,011,184...114,014,277
Ensembl chr 5:114,011,189...114,014,277
JBrowse link
G Junb JunB proto-oncogene, AP-1 transcription factor subunit increases expression EXP DDT results in increased expression of JUNB mRNA CTD PMID:30207508 NCBI chr19:26,092,972...26,094,756
Ensembl chr19:26,092,974...26,094,756
JBrowse link
G Kcnh2 potassium voltage-gated channel subfamily H member 2 decreases activity ISO DDT results in decreased activity of KCNH2 protein CTD PMID:28551711 NCBI chr 4:7,355,066...7,387,282
Ensembl chr 4:7,355,574...7,387,253
JBrowse link
G Kdm7a lysine demethylase 7A decreases expression EXP DDT results in decreased expression of KDM7A mRNA CTD PMID:30207508 NCBI chr 4:66,915,603...66,957,971
Ensembl chr 4:66,922,013...66,955,732
JBrowse link
G Kit KIT proto-oncogene receptor tyrosine kinase multiple interactions ISO [Hexachlorocyclohexane co-treated with Aldrin co-treated with Dieldrin co-treated with Endrin co-treated with Dichlorodiphenyl Dichloroethylene co-treated with Dichlorodiphenyldichloroethane co-treated with DDT co-treated with Simvastatin] results in increased expression of KIT mRNA CTD PMID:28263720 NCBI chr14:35,072,131...35,149,638
Ensembl chr14:35,072,108...35,149,610
JBrowse link
G Klk13 kallikrein related-peptidase 13 increases methylation EXP DDT results in increased methylation of KLK13 gene CTD PMID:30207508 NCBI chr 1:99,648,658...99,661,025
Ensembl chr 1:99,648,658...99,660,277
JBrowse link
G Krt18 keratin 18 decreases expression ISO DDT results in decreased expression of KRT18 protein CTD PMID:26186133 NCBI chr 7:143,629,455...143,633,131
Ensembl chr 7:143,629,455...143,633,131
JBrowse link
G Krt34 keratin 34 decreases expression ISO DDT results in decreased expression of KRT34 mRNA CTD PMID:25014179 NCBI chr10:87,950,364...87,954,055
Ensembl chr10:87,950,001...87,954,055
JBrowse link
G Krt8 keratin 8 decreases expression ISO DDT results in decreased expression of KRT8 protein CTD PMID:26186133 NCBI chr 7:143,596,511...143,603,745
Ensembl chr 7:143,596,511...143,603,803
JBrowse link
G Krtap16-1 keratin associated protein 16-1 increases methylation EXP DDT results in increased methylation of KRTAP16-1 gene CTD PMID:30207508 NCBI chr10:87,919,100...87,920,581
Ensembl chr10:87,919,100...87,920,581
Ensembl chr10:87,919,100...87,920,581
JBrowse link
G Ktn1 kinectin 1 increases expression ISO DDT results in increased expression of KTN1 mRNA CTD PMID:25014179 NCBI chr15:24,465,761...24,552,833
Ensembl chr15:24,479,761...24,553,197
JBrowse link
G Lbh LBH regulator of WNT signaling pathway increases expression ISO DDT results in increased expression of LBH mRNA CTD PMID:24814263 NCBI chr 6:24,154,207...24,184,217
Ensembl chr 6:24,160,226...24,181,866
JBrowse link
G Ldha lactate dehydrogenase A increases expression
multiple interactions
ISO DDT results in increased expression of LDHA mRNA
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [DDT results in increased expression of LDHA mRNA]; Acetylcysteine inhibits the reaction [DDT results in increased expression of LDHA mRNA]; PKM protein alternative form affects the reaction [DDT results in increased expression of LDHA mRNA]
CTD PMID:31724279 NCBI chr 1:102,900,288...102,909,713
Ensembl chr 1:102,900,286...102,909,707
JBrowse link
G Lep leptin increases expression ISO DDT results in increased expression of LEP mRNA CTD PMID:25014179 NCBI chr 4:56,337,695...56,351,818
Ensembl chr 4:56,337,695...56,351,818
JBrowse link
G Lgi2 leucine-rich repeat LGI family, member 2 decreases methylation EXP DDT results in decreased methylation of LGI2 gene CTD PMID:30207508 NCBI chr14:60,764,325...60,791,809
Ensembl chr14:60,764,409...60,796,116
JBrowse link
G Lhb luteinizing hormone subunit beta multiple interactions
increases expression
ISO 2-(2-chloro-4-iodophenylamino)-N-cyclopropylmethoxy-3,4-difluorobenzamide inhibits the reaction [DDT results in increased expression of LHB mRNA]
DDT results in increased expression of LHB protein
CTD PMID:24814263 NCBI chr 1:101,409,992...101,413,725
Ensembl chr 1:101,410,019...101,413,724
JBrowse link
G Lif LIF, interleukin 6 family cytokine increases expression ISO DDT results in increased expression of LIF mRNA CTD PMID:26198647 NCBI chr14:84,482,652...84,500,574
Ensembl chr14:84,482,674...84,500,642
JBrowse link
G Lmbrd2 LMBR1 domain containing 2 decreases expression EXP DDT results in decreased expression of LMBRD2 mRNA CTD PMID:30207508 NCBI chr 2:58,534,474...58,590,767
Ensembl chr 2:58,534,476...58,590,758
JBrowse link
G Lnpep leucyl and cystinyl aminopeptidase decreases expression EXP DDT results in decreased expression of LNPEP mRNA CTD PMID:30207508 NCBI chr 1:59,289,392...59,384,540
Ensembl chr 1:59,297,294...59,347,472
Ensembl chr 1:59,297,294...59,347,472
JBrowse link
G LOC100362109 hypothetical protein LOC100362109 decreases expression ISO DDT results in decreased expression of C22ORF46 mRNA CTD PMID:25014179 NCBI chr 7:123,295,519...123,304,163
Ensembl chr 7:123,296,183...123,304,066
JBrowse link
G Lox lysyl oxidase decreases expression EXP DDT results in decreased expression of LOX mRNA CTD PMID:30207508 NCBI chr18:47,500,320...47,577,819
Ensembl chr18:47,500,330...47,577,819
JBrowse link
G Loxhd1 lipoxygenase homology domains 1 increases methylation EXP DDT results in increased methylation of LOXHD1 gene CTD PMID:30207508 NCBI chr18:73,645,365...73,812,271
Ensembl chr18:73,645,907...73,812,271
JBrowse link
G Lpl lipoprotein lipase increases expression ISO DDT results in increased expression of LPL mRNA CTD PMID:25014179 NCBI chr16:22,537,687...22,561,487
Ensembl chr16:22,537,056...22,561,496
JBrowse link
G Lpp LIM domain containing preferred translocation partner in lipoma decreases expression
decreases methylation
EXP DDT results in decreased expression of LPP mRNA
DDT results in decreased methylation of LPP gene
CTD PMID:30207508 NCBI chr11:79,192,603...79,827,858
Ensembl chr11:79,205,730...79,703,736
JBrowse link
G Lratd2 LRAT domain containing 2 decreases methylation EXP DDT results in decreased methylation of LRATD2 gene CTD PMID:30207508 NCBI chr 7:101,138,188...101,142,123
Ensembl chr 7:101,139,376...101,140,308
JBrowse link
G Lrrc2 leucine rich repeat containing 2 multiple interactions ISO [Hexachlorocyclohexane co-treated with Aldrin co-treated with Dieldrin co-treated with Endrin co-treated with Dichlorodiphenyl Dichloroethylene co-treated with Dichlorodiphenyldichloroethane co-treated with DDT co-treated with Simvastatin] results in decreased expression of LRRC2 mRNA CTD PMID:28263720 NCBI chr 8:119,226,651...119,259,649
Ensembl chr 8:119,228,612...119,259,645
JBrowse link
G Lrrfip1 LRR binding FLII interacting protein 1 decreases expression EXP DDT results in decreased expression of LRRFIP1 mRNA CTD PMID:30207508 NCBI chr 9:98,139,484...98,268,148
Ensembl chr 9:98,190,829...98,257,735
JBrowse link
G Ltf lactotransferrin increases expression ISO DDT results in increased expression of LTF mRNA CTD PMID:9607801 NCBI chr 8:119,290,416...119,313,261
Ensembl chr 8:119,290,416...119,313,261
JBrowse link
G Lum lumican increases expression EXP DDT results in increased expression of LUM mRNA CTD PMID:30207508 NCBI chr 7:38,820,058...38,826,862
Ensembl chr 7:38,819,771...38,826,862
JBrowse link
G Luzp2 leucine zipper protein 2 decreases methylation EXP DDT results in decreased methylation of LUZP2 gene CTD PMID:30207508 NCBI chr 1:111,849,494...112,067,502
NCBI chr 1:113,419,707...113,531,330
Ensembl chr 1:111,849,998...113,527,735
JBrowse link
G Ly86 lymphocyte antigen 86 increases methylation EXP DDT results in increased methylation of LY86 gene CTD PMID:30207508 NCBI chr17:28,104,535...28,191,447
Ensembl chr17:28,104,589...28,191,436
JBrowse link
G Ly9 lymphocyte antigen 9 increases methylation EXP DDT results in increased methylation of LY9 gene CTD PMID:30207508 NCBI chr13:90,002,779...90,022,346
Ensembl chr13:90,002,783...90,022,269
JBrowse link
G M1ap meiosis 1 associated protein increases methylation EXP DDT results in increased methylation of M1AP gene CTD PMID:30207508 NCBI chr 4:113,772,716...113,864,171
Ensembl chr 4:113,782,206...113,863,224
JBrowse link
G Mab21l1 mab-21 like 1 decreases expression EXP DDT results in decreased expression of MAB21L1 mRNA CTD PMID:30207508 NCBI chr 2:145,174,876...145,177,265
Ensembl chr 2:145,174,876...145,177,265
JBrowse link
G Mageb1 melanoma antigen family B, 1 increases methylation EXP DDT results in increased methylation of MAGEB4 gene CTD PMID:30207508 NCBI chr  X:54,892,482...54,931,144 JBrowse link
G Manea mannosidase, endo-alpha decreases expression EXP DDT results in decreased expression of MANEA mRNA CTD PMID:30207508 NCBI chr 5:40,845,103...40,867,025
Ensembl chr 5:40,844,998...40,867,023
JBrowse link
G Map2 microtubule-associated protein 2 decreases expression EXP DDT results in decreased expression of MAP2 mRNA CTD PMID:30207508 NCBI chr 9:73,204,753...73,462,965
Ensembl chr 9:73,319,710...73,462,972
JBrowse link
G Map2k6 mitogen-activated protein kinase kinase 6 multiple interactions ISO MAP2K6 protein promotes the reaction [DDT results in increased activity of NOTCH1 protein] CTD PMID:18791200 NCBI chr10:98,707,160...98,823,054
Ensembl chr10:98,706,960...98,823,287
JBrowse link
G Mapk1 mitogen activated protein kinase 1 increases phosphorylation
multiple interactions
increases activity
ISO
EXP
DDT results in increased phosphorylation of MAPK1 protein
2-(2-chloro-4-iodophenylamino)-N-cyclopropylmethoxy-3,4-difluorobenzamide inhibits the reaction [DDT results in increased phosphorylation of MAPK1 protein]
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [DDT results in increased phosphorylation of MAPK1 protein]; Acetylcysteine inhibits the reaction [DDT results in increased phosphorylation of MAPK1 protein]; DDT results in increased phosphorylation of and results in increased activity of MAPK1 protein
DDT results in increased activity of MAPK1 protein
CTD PMID:9070211, PMID:12523960, PMID:14604893, PMID:24814263, PMID:31724279 NCBI chr11:88,203,863...88,273,301
Ensembl chr11:88,211,599...88,273,254
JBrowse link
G Mapk14 mitogen activated protein kinase 14 increases phosphorylation ISO DDT results in increased phosphorylation of MAPK14 protein CTD PMID:14604893 NCBI chr20:5,933,290...5,995,137
Ensembl chr20:5,933,303...5,995,137
JBrowse link
G Mapk3 mitogen activated protein kinase 3 increases phosphorylation
multiple interactions
ISO DDT results in increased phosphorylation of MAPK3 protein
2-(2-chloro-4-iodophenylamino)-N-cyclopropylmethoxy-3,4-difluorobenzamide inhibits the reaction [DDT results in increased phosphorylation of MAPK3 protein]
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [DDT results in increased phosphorylation of MAPK3 protein]; Acetylcysteine inhibits the reaction [DDT results in increased phosphorylation of MAPK3 protein]; DDT results in increased phosphorylation of and results in increased activity of MAPK3 protein
CTD PMID:9070211, PMID:14604893, PMID:24814263, PMID:31724279 NCBI chr 1:198,192,773...198,198,975
Ensembl chr 1:198,192,773...198,198,975
JBrowse link
G Mapk8 mitogen-activated protein kinase 8 decreases phosphorylation ISO DDT results in decreased phosphorylation of MAPK8 protein CTD PMID:14604893 NCBI chr16:9,620,854...9,709,342
Ensembl chr16:9,625,177...9,709,347
JBrowse link
G Mapk8ip3 mitogen-activated protein kinase 8 interacting protein 3 increases expression ISO DDT results in increased expression of MAPK8IP3 mRNA CTD PMID:25014179 NCBI chr10:14,259,394...14,299,276
Ensembl chr10:14,260,787...14,299,167
JBrowse link
G Mapk9 mitogen-activated protein kinase 9 decreases phosphorylation ISO DDT results in decreased phosphorylation of MAPK9 protein CTD PMID:14604893 NCBI chr10:35,333,859...35,374,364
Ensembl chr10:35,333,859...35,374,355
JBrowse link
G Matr3 matrin 3 decreases expression EXP DDT results in decreased expression of MATR3 mRNA CTD PMID:30207508 NCBI chr18:28,351,691...28,390,764
Ensembl chr18:28,361,283...28,390,717
JBrowse link
G Mcm4 minichromosome maintenance complex component 4 decreases expression ISO DDT results in decreased expression of MCM4 mRNA CTD PMID:25014179 NCBI chr11:89,511,191...89,524,892
Ensembl chr11:89,511,191...89,524,892
JBrowse link
G Mcur1 mitochondrial calcium uniporter regulator 1 increases methylation EXP DDT results in increased methylation of MCUR1 gene CTD PMID:30207508 NCBI chr17:24,165,259...24,182,425
Ensembl chr17:24,165,280...24,182,425
JBrowse link
G Mdm2 MDM2 proto-oncogene multiple interactions
increases expression
ISO Androstanols inhibits the reaction [DDT results in increased expression of MDM2 mRNA]
DDT results in increased expression of MDM2 mRNA; DDT results in increased expression of MDM2 protein
CTD PMID:23684557 NCBI chr 7:60,719,060...60,743,618
Ensembl chr 7:60,719,066...60,743,328
JBrowse link
G Mepe matrix extracellular phosphoglycoprotein increases methylation EXP DDT results in increased methylation of MEPE gene CTD PMID:30207508 NCBI chr14:6,782,011...6,793,561
Ensembl chr14:6,782,012...6,793,558
JBrowse link
G Mertk MER proto-oncogene, tyrosine kinase multiple interactions ISO [Hexachlorocyclohexane co-treated with Aldrin co-treated with Dieldrin co-treated with Endrin co-treated with Dichlorodiphenyl Dichloroethylene co-treated with Dichlorodiphenyldichloroethane co-treated with DDT co-treated with Simvastatin] results in decreased expression of MERTK mRNA CTD PMID:28263720 NCBI chr 3:121,235,230...121,340,932
Ensembl chr 3:121,235,119...121,342,444
JBrowse link
G Met MET proto-oncogene, receptor tyrosine kinase increases phosphorylation ISO DDT results in increased phosphorylation of MET protein CTD PMID:9070211 NCBI chr 4:44,747,467...44,854,628
Ensembl chr 4:44,774,741...44,852,665
JBrowse link
G Mfap3l microfibril associated protein 3 like decreases expression EXP DDT results in decreased expression of MFAP3L mRNA CTD PMID:30207508 NCBI chr16:32,734,059...32,777,091
Ensembl chr16:32,738,265...32,753,278
JBrowse link
G Mgp matrix Gla protein increases expression EXP DDT results in increased expression of MGP mRNA CTD PMID:30207508 NCBI chr 4:170,856,783...170,860,105
Ensembl chr 4:170,856,751...170,860,225
JBrowse link
G Mir15b microRNA 15b decreases expression ISO DDT results in decreased expression of MIR15B mRNA CTD PMID:22403704 NCBI chr 2:165,605,923...165,606,020
Ensembl chr 2:165,605,923...165,606,020
JBrowse link
G Mir190 microRNA 190 increases expression EXP DDT results in increased expression of MIR190 mRNA CTD PMID:30421125 NCBI chr 8:73,030,047...73,030,131
Ensembl chr 8:73,030,047...73,030,131
JBrowse link
G Mir190b microRNA 190b increases expression ISO
EXP
DDT results in increased expression of MIR190B mRNA CTD PMID:30421125 NCBI chr 2:189,421,137...189,421,214
Ensembl chr 2:189,421,137...189,421,214
JBrowse link
G Mir193a microRNA 193a increases expression ISO DDT results in increased expression of MIR193A mRNA CTD PMID:22403704 NCBI chr10:67,065,885...67,065,996
Ensembl chr10:67,065,885...67,065,996
JBrowse link
G Mir202 microRNA 202 increases expression EXP DDT results in increased expression of MIR202 mRNA CTD PMID:30207508 NCBI chr 1:212,295,630...212,295,701
Ensembl chr 1:212,295,630...212,295,701
JBrowse link
G Mir21 microRNA 21 decreases expression ISO DDT results in decreased expression of MIR21 mRNA CTD PMID:22403704 NCBI chr10:73,902,210...73,902,301
Ensembl chr10:73,902,210...73,902,301
JBrowse link
G Mir27b microRNA 27b decreases expression ISO DDT results in decreased expression of MIR27B mRNA CTD PMID:22403704 NCBI chr17:823,461...823,557
Ensembl chr17:823,461...823,557
JBrowse link
G Mir342 microRNA 342 decreases expression ISO DDT results in decreased expression of MIR342 mRNA CTD PMID:22403704 NCBI chr 6:132,561,169...132,561,267
Ensembl chr 6:132,561,169...132,561,267
JBrowse link
G Mir34b microRNA 34b decreases expression EXP DDT results in decreased expression of MIR34B mRNA CTD PMID:30207508 NCBI chr 8:55,492,542...55,492,625
Ensembl chr 8:55,492,542...55,492,625
JBrowse link
G Mir34c microRNA 34c decreases expression EXP DDT results in decreased expression of MIR34C mRNA CTD PMID:30207508 NCBI chr 8:55,492,024...55,492,100
Ensembl chr 8:55,492,024...55,492,100
JBrowse link
G Mir374b microRNA 374b increases expression EXP DDT results in increased expression of MIR374 mRNA CTD PMID:30207508 NCBI chr  X:74,443,648...74,443,715
Ensembl chr  X:74,443,648...74,443,715
JBrowse link
G Mir6333 microRNA 6333 increases methylation EXP DDT results in increased methylation of MIR6333 gene CTD PMID:30207508 NCBI chr 5:153,843,901...153,844,011
Ensembl chr 5:153,843,901...153,844,011
JBrowse link
G Mir92b microRNA 92b decreases expression ISO DDT results in decreased expression of MIR92B mRNA CTD PMID:22403704 NCBI chr 2:188,541,034...188,541,116
Ensembl chr 2:188,541,034...188,541,116
JBrowse link
G Mir99b microRNA 99b decreases expression ISO DDT results in decreased expression of MIR99B mRNA CTD PMID:22403704 NCBI chr 1:59,704,216...59,704,285
Ensembl chr 1:59,704,216...59,704,285
JBrowse link
G Mirlet7b microRNA let-7b decreases expression EXP DDT results in decreased expression of MIRLET7B mRNA CTD PMID:30207508 NCBI chr 7:126,590,627...126,590,711
Ensembl chr 7:126,590,627...126,590,711
JBrowse link
G Mitf melanocyte inducing transcription factor increases methylation EXP DDT results in increased methylation of MITF gene CTD PMID:30207508 NCBI chr 4:130,172,484...130,425,496
Ensembl chr 4:130,172,727...130,425,532
JBrowse link
G Mmadhc metabolism of cobalamin associated D increases methylation EXP DDT results in increased methylation of MMADHC gene CTD PMID:30207508 NCBI chr 3:35,783,511...35,801,474
Ensembl chr 3:35,783,623...35,801,614
JBrowse link
G Mme membrane metallo-endopeptidase decreases expression EXP DDT results in decreased expression of MME mRNA CTD PMID:30207508 NCBI chr 2:153,799,203...153,880,910
Ensembl chr 2:153,803,349...153,880,738
JBrowse link
G Mmp2 matrix metallopeptidase 2 increases expression EXP DDT results in increased expression of MMP2 mRNA CTD PMID:30207508 NCBI chr19:15,542,771...15,570,589
Ensembl chr19:15,542,765...15,570,611
JBrowse link
G Mmp3 matrix metallopeptidase 3 multiple interactions
increases expression
ISO 13-hydroxy-10-oxo-11-octadecenoic acid inhibits the reaction [DDT results in increased expression of MMP3 mRNA]; zerumbone inhibits the reaction [DDT results in increased expression of MMP3 mRNA] CTD PMID:20865247 NCBI chr 8:5,676,608...5,698,579
Ensembl chr 8:5,676,665...5,698,579
JBrowse link
G Mogs mannosyl-oligosaccharide glucosidase decreases expression EXP DDT results in decreased expression of MOGS mRNA CTD PMID:30207508 NCBI chr 4:113,948,328...113,951,731
Ensembl chr 4:113,948,514...113,951,847
JBrowse link
G Msx1 msh homeobox 1 decreases expression EXP DDT results in decreased expression of MSX1 mRNA CTD PMID:19797855 NCBI chr14:77,712,262...77,716,061
Ensembl chr14:77,712,240...77,716,059
JBrowse link
G Mt2A metallothionein 2A multiple interactions
decreases expression
ISO MT2A protein inhibits the reaction [DDT results in decreased expression of HSD17B1 mRNA]
DDT results in decreased expression of MT2A mRNA
CTD PMID:12858341, PMID:25014179 NCBI chr19:11,307,966...11,308,740
Ensembl chr19:11,307,967...11,308,740
JBrowse link
G Muc6 mucin 6, oligomeric mucus/gel-forming increases methylation EXP DDT results in increased methylation of MUC6 gene CTD PMID:30207508 NCBI chr 1:214,608,453...214,630,524
Ensembl chr 1:214,608,704...214,629,938
JBrowse link
G Myc MYC proto-oncogene, bHLH transcription factor multiple interactions
increases expression
EXP
ISO
[EGF protein co-treated with DDT] results in increased expression of MYC mRNA
DDT results in increased expression of MYC protein
fulvestrant inhibits the reaction [DDT results in increased expression of MYC mRNA]
DDT results in increased expression of MYC mRNA; DDT results in increased expression of MYC protein
CTD PMID:12632255, PMID:23684557, PMID:24968063 NCBI chr 7:102,586,313...102,591,240
Ensembl chr 7:102,586,313...102,591,240
JBrowse link
G Myh11 myosin heavy chain 11 increases expression EXP DDT results in increased expression of MYH11 mRNA CTD PMID:30207508 NCBI chr10:764,421...859,184
Ensembl chr10:764,421...859,184
JBrowse link
G Nav1 neuron navigator 1 increases methylation EXP DDT results in increased methylation of NAV1 gene CTD PMID:30207508 NCBI chr13:52,260,474...52,515,016
Ensembl chr13:52,267,254...52,514,875
JBrowse link
G Nfe2l2 nuclear factor, erythroid 2-like 2 increases expression ISO DDT results in increased expression of NFE2L2 mRNA CTD PMID:31521043 NCBI chr 3:62,497,568...62,525,146
Ensembl chr 3:62,497,571...62,524,996
JBrowse link
G Nfkb1 nuclear factor kappa B subunit 1 decreases expression ISO DDT results in decreased expression of NFKB1 protein CTD PMID:16696175 NCBI chr 2:240,773,520...240,890,053
Ensembl chr 2:240,773,456...240,866,689
JBrowse link
G Nhsl2 NHS-like 2 increases methylation EXP DDT results in increased methylation of NHSL2 gene CTD PMID:30207508 NCBI chr  X:71,895,202...71,980,019 JBrowse link
G Nid1 nidogen 1 increases expression EXP DDT results in increased expression of NID1 mRNA CTD PMID:30207508 NCBI chr17:90,553,161...90,627,133
Ensembl chr17:90,553,394...90,627,101
JBrowse link
G Nipal3 NIPA-like domain containing 3 increases methylation EXP DDT results in increased methylation of NIPAL3 gene CTD PMID:30207508 NCBI chr 5:153,808,169...153,843,961
Ensembl chr 5:153,807,955...153,840,178
JBrowse link
G Nlrc5 NLR family, CARD domain containing 5 increases methylation EXP DDT results in increased methylation of NLRC5 gene CTD PMID:30207508 NCBI chr19:10,904,381...11,006,202
Ensembl chr19:10,905,542...10,976,396
JBrowse link
G Nlrp5 NLR family, pyrin domain containing 5 decreases expression EXP DDT results in decreased expression of NLRP5 mRNA CTD PMID:30207508 NCBI chr 1:71,452,184...71,490,915
Ensembl chr 1:71,453,798...71,486,790
JBrowse link
G Nos2 nitric oxide synthase 2 decreases expression
multiple interactions
increases expression
EXP
ISO
DDT results in decreased expression of NOS2 mRNA
[DDT co-treated with o,p'-DDT] results in decreased expression of NOS2 mRNA
DDT results in increased expression of NOS2 mRNA
DDT metabolite results in decreased expression of NOS2 mRNA; DDT results in decreased expression of NOS2 mRNA
CTD PMID:11948501, PMID:12007859 NCBI chr10:66,188,290...66,221,621
Ensembl chr10:66,189,786...66,313,190
JBrowse link
G Notch1 notch receptor 1 increases activity
multiple interactions
ISO DDT results in increased activity of NOTCH1 protein
MAP2K6 protein promotes the reaction [DDT results in increased activity of NOTCH1 protein]
CTD PMID:18791200 NCBI chr 3:3,905,562...3,951,015
Ensembl chr 3:3,905,453...3,951,025
JBrowse link
G Nqo1 NAD(P)H quinone dehydrogenase 1 increases expression ISO DDT results in increased expression of NQO1 mRNA CTD PMID:31521043 NCBI chr19:38,422,210...38,437,103
Ensembl chr19:38,422,164...38,437,180
JBrowse link
G Nr1i2 nuclear receptor subfamily 1, group I, member 2 multiple interactions
increases activity
ISO [DDT co-treated with Dieldrin] results in increased activity of NR1I2 protein; DDT binds to and results in increased activity of NR1I2 protein
DDT results in increased activity of NR1I2 protein
CTD PMID:15548381, PMID:16054614, PMID:20686338, PMID:25028461, PMID:25680588 NCBI chr11:65,022,100...65,058,546
Ensembl chr11:65,022,100...65,058,545
JBrowse link
G Nr1i3 nuclear receptor subfamily 1, group I, member 3 increases expression
increases activity
multiple interactions
ISO DDT results in increased expression of NR1I3 mRNA
DDT results in increased activity of NR1I3 protein
DDT inhibits the reaction [Androstenols results in decreased activity of NR1I3 protein]; DDT promotes the reaction [NR1I3 protein binds to CYP2B10 promoter]
DDT binds to and results in increased activity of and results in increased localization of NR1I3 protein mutant form
CTD PMID:16929008, PMID:19746742, PMID:20686338, PMID:23684557, PMID:28927721 NCBI chr13:89,585,072...89,591,278
Ensembl chr13:89,586,283...89,591,277
JBrowse link
G Nr3c1 nuclear receptor subfamily 3, group C, member 1 multiple interactions ISO DDT inhibits the reaction [Hydrocortisone results in increased activity of NR3C1 protein] CTD PMID:26647222 NCBI chr18:31,728,373...32,704,022
Ensembl chr18:31,728,373...31,749,647
JBrowse link
G Nr3c2 nuclear receptor subfamily 3, group C, member 2 multiple interactions ISO DDT inhibits the reaction [Aldosterone affects the localization of NR3C2 protein]; DDT inhibits the reaction [Aldosterone results in increased activity of NR3C2 protein] CTD PMID:29149346 NCBI chr19:34,408,275...34,761,003
Ensembl chr19:34,448,289...34,752,695
JBrowse link
G Nrxn1 neurexin 1 increases methylation EXP DDT results in increased methylation of NRXN1 gene CTD PMID:30207508 NCBI chr 6:13,886,757...15,191,660
Ensembl chr 6:13,886,740...15,191,660
JBrowse link
G Nrxn3 neurexin 3 increases methylation EXP DDT results in increased methylation of NRXN3 gene CTD PMID:30207508 NCBI chr 6:112,133,204...114,069,589
Ensembl chr 6:112,133,204...114,067,564
JBrowse link
G Ntn1 netrin 1 increases methylation EXP DDT results in increased methylation of NTN1 gene CTD PMID:30207508 NCBI chr10:54,761,925...54,982,072
Ensembl chr10:54,761,871...54,967,585
JBrowse link
G Ntn4 netrin 4 decreases expression EXP DDT results in decreased expression of NTN4 mRNA CTD PMID:30207508 NCBI chr 7:34,533,543...34,649,330
Ensembl chr 7:34,533,543...34,649,481
JBrowse link
G Ntrk1 neurotrophic receptor tyrosine kinase 1 multiple interactions ISO [Hexachlorocyclohexane co-treated with Aldrin co-treated with Dieldrin co-treated with Endrin co-treated with Dichlorodiphenyl Dichloroethylene co-treated with Dichlorodiphenyldichloroethane co-treated with DDT co-treated with Simvastatin] results in increased expression of NTRK1 mRNA CTD PMID:28263720 NCBI chr 2:187,143,568...187,160,373
Ensembl chr 2:187,143,568...187,160,373
JBrowse link
G Ntrk2 neurotrophic receptor tyrosine kinase 2 multiple interactions ISO [Hexachlorocyclohexane co-treated with Aldrin co-treated with Dieldrin co-treated with Endrin co-treated with Dichlorodiphenyl Dichloroethylene co-treated with Dichlorodiphenyldichloroethane co-treated with DDT co-treated with Simvastatin] results in increased expression of NTRK2 mRNA CTD PMID:28263720 NCBI chr17:5,934,651...6,245,778
Ensembl chr17:5,933,729...6,244,676
JBrowse link
G Nvl nuclear VCP-like increases methylation EXP DDT results in increased methylation of NVL gene CTD PMID:30207508 NCBI chr13:99,410,026...99,468,783
Ensembl chr13:99,410,026...99,468,778
JBrowse link
G Ogfod3 2-oxoglutarate and iron-dependent oxygenase domain containing 3 increases methylation EXP DDT results in increased methylation of OGFOD3 gene CTD PMID:30207508 NCBI chr10:110,378,533...110,406,377
Ensembl chr10:110,378,534...110,406,377
JBrowse link
G Ogg1 8-oxoguanine DNA glycosylase multiple interactions
increases expression
EXP [DDT co-treated with Diethylnitrosamine] results in decreased expression of OGG1 mRNA; [DDT co-treated with Diethylnitrosamine] results in increased expression of OGG1 mRNA
DDT results in increased expression of OGG1 mRNA
CTD PMID:11948501, PMID:15885732 NCBI chr 4:145,282,828...145,289,367
Ensembl chr 4:145,282,797...145,289,326
JBrowse link
G Ogt O-linked N-acetylglucosamine (GlcNAc) transferase increases expression
increases methylation
ISO
EXP
DDT results in increased expression of OGT mRNA
DDT results in increased methylation of OGT gene
CTD PMID:25014179, PMID:30207508 NCBI chr  X:71,540,870...71,585,906
Ensembl chr  X:71,528,988...71,585,908
JBrowse link
G Olr1135 olfactory receptor 1135 decreases methylation EXP DDT results in decreased methylation of OLR1135 gene CTD PMID:30207508 NCBI chr 8:19,081,540...19,082,478
Ensembl chr 8:19,081,540...19,082,478
JBrowse link
G Olr1442 olfactory receptor 1442 increases methylation EXP DDT results in increased methylation of OLR1442 gene CTD PMID:30207508 NCBI chr10:44,527,468...44,528,382
Ensembl chr10:44,527,468...44,528,382
JBrowse link
G Olr1757-ps olfactory receptor pseudogene 1757 increases methylation EXP DDT results in increased methylation of OLR1757-PS gene CTD PMID:30207508 NCBI chr 4:33,140,048...33,140,509 JBrowse link
G Ophn1 oligophrenin 1 decreases methylation EXP DDT results in decreased methylation of OPHN1 gene CTD PMID:30207508 NCBI chr  X:68,185,865...68,579,518
Ensembl chr  X:68,189,161...68,563,137
JBrowse link
G Pamr1 peptidase domain containing associated with muscle regeneration 1 decreases expression EXP DDT results in decreased expression of PAMR1 mRNA CTD PMID:30207508 NCBI chr 3:92,403,533...92,502,094
Ensembl chr 3:92,403,582...92,502,089
JBrowse link
G Pard3 par-3 family cell polarity regulator increases methylation EXP DDT results in increased methylation of PARD3 gene CTD PMID:30207508 NCBI chr19:60,017,746...60,580,628
Ensembl chr19:60,017,746...60,580,651
JBrowse link
G Pcdh20 protocadherin 20 decreases expression EXP DDT results in decreased expression of PCDH20 mRNA CTD PMID:30207508 NCBI chr15:71,772,777...71,779,033
Ensembl chr15:71,772,777...71,779,033
JBrowse link
G Pcdh9 protocadherin 9 decreases expression EXP DDT results in decreased expression of PCDH9 mRNA CTD PMID:30207508 NCBI chr15:76,787,108...77,738,668
Ensembl chr15:77,733,402...77,736,892
JBrowse link
G Pck1 phosphoenolpyruvate carboxykinase 1 multiple interactions EXP DDT inhibits the reaction [Hydrocortisone results in increased expression of PCK1 mRNA] CTD PMID:26647222 NCBI chr 3:171,213,936...171,219,885
Ensembl chr 3:171,213,936...171,219,871
JBrowse link
G Pclo piccolo (presynaptic cytomatrix protein) decreases expression EXP DDT results in decreased expression of PCLO mRNA CTD PMID:30207508 NCBI chr 4:16,454,904...17,058,921
Ensembl chr 4:16,454,904...17,058,921
JBrowse link
G Pdcd4 programmed cell death 4 increases expression ISO DDT results in increased expression of PDCD4 mRNA CTD PMID:22403704 NCBI chr 1:274,616,625...274,648,204
Ensembl chr 1:274,625,224...274,648,204
JBrowse link
G Pde7b phosphodiesterase 7B decreases expression EXP DDT results in decreased expression of PDE7B mRNA CTD PMID:30207508 NCBI chr 1:15,889,845...16,203,909
Ensembl chr 1:15,893,533...16,203,909
JBrowse link
G Pdgfra platelet derived growth factor receptor alpha increases expression EXP DDT results in increased expression of PDGFRA mRNA CTD PMID:30207508 NCBI chr14:35,527,926...35,581,130
Ensembl chr14:35,527,927...35,581,031
JBrowse link
G Pdgfrb platelet derived growth factor receptor beta multiple interactions ISO [Hexachlorocyclohexane co-treated with Aldrin co-treated with Dieldrin co-treated with Endrin co-treated with Dichlorodiphenyl Dichloroethylene co-treated with Dichlorodiphenyldichloroethane co-treated with DDT co-treated with Simvastatin] results in increased expression of PDGFRB mRNA CTD PMID:28263720 NCBI chr18:56,364,586...56,406,381
Ensembl chr18:56,364,620...56,406,381
JBrowse link
G Pdk1 pyruvate dehydrogenase kinase 1 increases expression
multiple interactions
ISO DDT results in increased expression of PDK1 mRNA
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [DDT results in increased expression of PDK1 mRNA]; Acetylcysteine inhibits the reaction [DDT results in increased expression of PDK1 mRNA]; PKM protein alternative form affects the reaction [DDT results in increased expression of PDK1 mRNA]
CTD PMID:31724279 NCBI chr 3:58,530,870...58,561,494
Ensembl chr 3:58,530,870...58,558,027
JBrowse link
G Pdlim3 PDZ and LIM domain 3 decreases expression EXP DDT results in decreased expression of PDLIM3 mRNA CTD PMID:30207508 NCBI chr16:49,543,140...49,574,362
Ensembl chr16:49,543,142...49,574,390
JBrowse link
G Penk proenkephalin decreases expression EXP DDT results in decreased expression of PENK mRNA CTD PMID:19797855 NCBI chr 5:17,056,412...17,061,762
Ensembl chr 5:17,056,419...17,061,837
JBrowse link
G Pgf placental growth factor decreases methylation EXP DDT results in decreased methylation of PGF gene CTD PMID:30207508 NCBI chr 6:108,994,016...109,004,598
Ensembl chr 6:108,994,018...109,004,598
JBrowse link
G Pgr progesterone receptor affects binding
increases expression
multiple interactions
ISO DDT binds to PGR protein
DDT results in increased expression of PGR mRNA
[DDT results in increased activity of ESR1 protein] which results in increased expression of PGR mRNA; DDT inhibits the reaction [16 alpha-ethyl-21-hydroxy-19-nor-4-pregnene-3,20-dione results in increased activity of PGR protein]; DDT inhibits the reaction [Progesterone binds to PGR protein]; DDT inhibits the reaction [Progesterone results in increased expression of PGR protein]
CTD PMID:9607801, PMID:14579009, PMID:15541753, PMID:18262749, PMID:22403704, PMID:26022396 NCBI chr 8:7,128,656...7,187,796
Ensembl chr 8:7,128,656...7,187,796
JBrowse link
G Phex phosphate regulating endopeptidase homolog, X-linked decreases expression EXP DDT results in decreased expression of PHEX mRNA CTD PMID:30207508 NCBI chr  X:40,460,047...40,717,982
Ensembl chr  X:40,460,047...40,717,982
JBrowse link
G Phf3 PHD finger protein 3 decreases methylation EXP DDT results in decreased methylation of PHF3 gene CTD PMID:30207508 NCBI chr 9:37,073,514...37,144,027
Ensembl chr 9:37,073,514...37,144,015
JBrowse link
G Pik3c2a phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha decreases expression EXP DDT results in decreased expression of PIK3C2A mRNA CTD PMID:30207508 NCBI chr 1:185,210,922...185,326,314
Ensembl chr 1:185,210,922...185,326,314
JBrowse link
G Pkm pyruvate kinase M1/2 multiple interactions
increases expression
ISO 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [DDT results in increased expression of and affects the localization of PKM protein alternative form]; 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [DDT results in increased expression of PKM mRNA alternative form]; Acetylcysteine inhibits the reaction [DDT results in increased expression of and affects the localization of PKM protein alternative form]; Acetylcysteine inhibits the reaction [DDT results in increased expression of PKM mRNA alternative form]; DDT results in increased expression of and affects the localization of PKM protein alternative form; PKM protein alternative form affects the reaction [DDT results in increased expression of LDHA mRNA]; PKM protein alternative form affects the reaction [DDT results in increased expression of PDK1 mRNA]; PKM protein alternative form affects the reaction [DDT results in increased expression of SLC2A1 mRNA] CTD PMID:31724279 NCBI chr 8:64,480,963...64,502,957
Ensembl chr 8:64,481,172...64,502,722
JBrowse link
G Pkp4 plakophilin 4 increases methylation EXP DDT results in increased methylation of PKP4 gene CTD PMID:30207508 NCBI chr 3:45,211,097...45,414,524
Ensembl chr 3:45,277,348...45,414,613
JBrowse link
G Plat plasminogen activator, tissue type decreases expression ISO DDT results in decreased expression of PLAT mRNA CTD PMID:25014179 NCBI chr16:74,098,263...74,122,897
Ensembl chr16:74,098,260...74,122,889
JBrowse link
G Pld4 phospholipase D family, member 4 increases methylation EXP DDT results in increased methylation of PLD4 gene CTD PMID:30207508 NCBI chr 6:137,323,713...137,331,231
Ensembl chr 6:137,323,713...137,331,231
JBrowse link
G Pls3 plastin 3 decreases expression EXP DDT results in decreased expression of PLS3 mRNA CTD PMID:30207508 NCBI chr  X:119,030,311...119,124,268
Ensembl chr  X:119,030,419...119,124,250
JBrowse link
G Plxdc2 plexin domain containing 2 decreases expression EXP DDT results in decreased expression of PLXDC2 mRNA CTD PMID:30207508 NCBI chr17:83,221,795...83,619,291
Ensembl chr17:83,221,827...83,610,272
JBrowse link
G Plxnd1 plexin D1 multiple interactions ISO [Hexachlorocyclohexane co-treated with Aldrin co-treated with Dieldrin co-treated with Endrin co-treated with Dichlorodiphenyl Dichloroethylene co-treated with Dichlorodiphenyldichloroethane co-treated with DDT co-treated with Simvastatin] results in decreased expression of PLXND1 mRNA CTD PMID:28263720 NCBI chr 4:147,854,309...147,894,170
Ensembl chr 4:147,854,309...147,893,992
JBrowse link
G Pnpla8 patatin-like phospholipase domain containing 8 decreases expression EXP DDT results in decreased expression of PNPLA8 mRNA CTD PMID:30207508 NCBI chr 6:64,224,870...64,288,465
Ensembl chr 6:64,224,861...64,286,785
JBrowse link
G Podxl podocalyxin-like decreases expression ISO DDT results in decreased expression of PODXL mRNA CTD PMID:25014179 NCBI chr 4:58,829,049...58,893,353
Ensembl chr 4:58,829,060...58,893,170
JBrowse link
G Polq DNA polymerase theta decreases methylation EXP DDT results in decreased methylation of POLQ gene CTD PMID:30207508 NCBI chr11:66,585,860...66,695,369
Ensembl chr11:66,585,881...66,695,353
JBrowse link
G Pomc proopiomelanocortin multiple interactions ISO [Hexachlorocyclohexane co-treated with DDT] results in increased expression of POMC CTD PMID:16329587 NCBI chr 6:28,382,937...28,388,771
Ensembl chr 6:28,382,962...28,388,967
JBrowse link
G Potem POTE ankyrin domain family member M increases methylation EXP DDT results in increased methylation of POTEM gene CTD PMID:30207508 NCBI chr16:21,947,702...22,118,777
Ensembl chr16:21,955,168...22,116,834
JBrowse link
G Pparg peroxisome proliferator-activated receptor gamma multiple interactions
increases expression
ISO DDT results in increased activity of and results in increased localization of PPARG protein
DDT results in increased expression of PPARG mRNA
CTD PMID:11911853, PMID:25014179 NCBI chr 4:147,274,055...147,399,383
Ensembl chr 4:147,274,107...147,399,380
JBrowse link
G Ppargc1a PPARG coactivator 1 alpha multiple interactions ISO DDT promotes the reaction [PPARGC1A protein binds to CYP2B10 promoter] CTD PMID:23684557 NCBI chr14:63,095,291...63,190,688
Ensembl chr14:63,095,720...63,187,009
JBrowse link
G Ppp2r2b protein phosphatase 2, regulatory subunit B, beta increases methylation EXP DDT results in increased methylation of PPP2R2B gene CTD PMID:30207508 NCBI chr18:36,985,709...37,421,383
Ensembl chr18:36,985,714...37,245,809
JBrowse link
G Prex2 phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 2 decreases expression EXP DDT results in decreased expression of PREX2 mRNA CTD PMID:30207508 NCBI chr 5:7,622,668...7,941,715
Ensembl chr 5:7,627,771...7,941,822
JBrowse link
G Prkaa2 protein kinase AMP-activated catalytic subunit alpha 2 decreases expression EXP DDT results in decreased expression of PRKAA2 mRNA CTD PMID:30207508 NCBI chr 5:124,568,845...124,642,569
Ensembl chr 5:124,574,079...124,642,569
JBrowse link
G Pros1 protein S decreases expression EXP DDT results in decreased expression of PROS1 mRNA CTD PMID:30207508 NCBI chr 7:1,206,648...1,288,140
Ensembl chr 7:1,206,648...1,288,134
JBrowse link
G Ptgs1 prostaglandin-endoperoxide synthase 1 decreases expression ISO DDT results in decreased expression of PTGS1 mRNA CTD PMID:25014179 NCBI chr 3:15,560,685...15,582,339
Ensembl chr 3:15,560,712...15,582,344
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 multiple interactions
increases expression
ISO aurapten inhibits the reaction [DDT results in increased expression of PTGS2 mRNA]; zerumbone inhibits the reaction [DDT results in increased expression of PTGS2 mRNA] CTD PMID:20865247 NCBI chr13:67,351,230...67,356,920
Ensembl chr13:67,351,087...67,359,335
JBrowse link
G Ptprm protein tyrosine phosphatase, receptor type, M decreases methylation EXP DDT results in decreased methylation of PTPRM gene CTD PMID:30207508 NCBI chr 9:114,846,095...115,555,261
Ensembl chr 9:114,846,095...115,555,261
JBrowse link
G Qser1 glutamine and serine rich 1 decreases expression EXP DDT results in decreased expression of QSER1 mRNA CTD PMID:30207508 NCBI chr 3:94,702,635...94,767,364
Ensembl chr 3:94,702,663...94,767,239
JBrowse link
G Rab4b RAB4B, member RAS oncogene family increases methylation EXP DDT results in increased methylation of RAB4B gene CTD PMID:30207508 NCBI chr 1:83,979,298...83,990,680
Ensembl chr 1:83,979,298...83,990,588
JBrowse link
G Rabggtb Rab geranylgeranyltransferase subunit beta increases expression ISO DDT results in increased expression of RABGGTB mRNA CTD PMID:25014179 NCBI chr 2:260,110,309...260,115,574
Ensembl chr 2:260,110,309...260,115,577
JBrowse link
G Rack1 receptor for activated C kinase 1 decreases expression ISO DDT results in decreased expression of RACK1 mRNA; DDT results in decreased expression of RACK1 protein CTD PMID:28412309 NCBI chr10:34,149,717...34,155,198
Ensembl chr10:34,149,717...34,155,198
Ensembl chr12:34,149,717...34,155,198
JBrowse link
G Ranbp2 RAN binding protein 2 decreases expression EXP DDT results in decreased expression of RANBP2 mRNA CTD PMID:30207508 NCBI chr20:28,027,054...28,076,664
NCBI chr20:28,365,538...28,375,676
Ensembl chr20:28,027,054...28,076,664
Ensembl chr20:28,027,054...28,076,664
JBrowse link
G Rasef RAS and EF hand domain containing decreases expression EXP DDT results in decreased expression of RASEF mRNA CTD PMID:30207508 NCBI chr 5:90,419,044...90,488,882
Ensembl chr 5:90,419,020...90,488,896
JBrowse link
G Rb1 RB transcriptional corepressor 1 increases phosphorylation ISO DDT results in increased phosphorylation of RB1 protein CTD PMID:9049186, PMID:23684557 NCBI chr15:55,081,582...55,209,060
Ensembl chr15:55,083,140...55,209,342
JBrowse link
G Rb1cc1 RB1-inducible coiled-coil 1 decreases expression EXP DDT results in decreased expression of RB1CC1 mRNA CTD PMID:30207508 NCBI chr 5:13,033,918...13,097,369
Ensembl chr 5:13,033,918...13,097,341
JBrowse link
G Rcan2 regulator of calcineurin 2 decreases expression EXP DDT results in decreased expression of RCAN2 mRNA CTD PMID:30207508 NCBI chr 9:19,518,568...19,749,145
Ensembl chr 9:19,518,558...19,749,145
JBrowse link
G Rcn2 reticulocalbin 2 decreases expression EXP DDT results in decreased expression of RCN2 mRNA CTD PMID:30207508 NCBI chr 8:60,709,851...60,726,938
Ensembl chr 8:60,709,851...60,726,936
JBrowse link
G Ret ret proto-oncogene multiple interactions ISO [Hexachlorocyclohexane co-treated with Aldrin co-treated with Dieldrin co-treated with Endrin co-treated with Dichlorodiphenyl Dichloroethylene co-treated with Dichlorodiphenyldichloroethane co-treated with DDT co-treated with Simvastatin] results in decreased expression of RET mRNA CTD PMID:28263720 NCBI chr 4:150,202,170...150,249,196
Ensembl chr 4:150,202,058...150,244,372
JBrowse link
G Rftn1 raftlin lipid raft linker 1 decreases methylation EXP DDT results in decreased methylation of RFTN1 gene CTD PMID:30207508 NCBI chr 9:12,740,885...12,942,358
Ensembl chr 9:12,740,885...12,942,358
JBrowse link
G RGD1309104 similar to RIKEN cDNA 1700025G04 gene increases methylation EXP DDT results in increased methylation of RGD1309104 gene CTD PMID:30207508 NCBI chr13:69,265,649...69,434,447
Ensembl chr13:69,265,649...69,385,074
JBrowse link
G Ripk4 receptor-interacting serine-threonine kinase 4 increases methylation EXP DDT results in increased methylation of RIPK4 gene CTD PMID:30207508 NCBI chr11:38,251,991...38,274,234
Ensembl chr11:38,251,955...38,274,217
JBrowse link
G Rlf RLF zinc finger decreases expression EXP DDT results in decreased expression of RLF mRNA CTD PMID:30207508 NCBI chr 5:140,107,144...140,162,698
Ensembl chr 5:140,107,275...140,162,642
JBrowse link
G Rnf150 ring finger protein 150 increases methylation EXP DDT results in increased methylation of RNF150 gene CTD PMID:30207508 NCBI chr19:24,044,210...24,264,508
Ensembl chr19:24,044,103...24,265,444
JBrowse link
G Rnf152 ring finger protein 152 increases methylation EXP DDT results in increased methylation of RNF152 gene CTD PMID:30207508 NCBI chr13:25,183,295...25,262,785
Ensembl chr13:25,186,106...25,262,469
JBrowse link
G Rnf181 ring finger protein 181 decreases expression ISO DDT results in decreased expression of RNF181 mRNA CTD PMID:25014179 NCBI chr 4:100,222,087...100,228,809
Ensembl chr 4:100,222,106...100,228,809
JBrowse link
G Rock2 Rho-associated coiled-coil containing protein kinase 2 decreases expression EXP DDT results in decreased expression of ROCK2 mRNA CTD PMID:30207508 NCBI chr 6:42,180,864...42,289,910
Ensembl chr 6:42,180,894...42,289,908
JBrowse link
G Rpl4 ribosomal protein L4 increases expression ISO DDT results in increased expression of RPL4 mRNA CTD PMID:25014179 NCBI chr 8:69,121,682...69,126,805
Ensembl chr 8:69,121,682...69,126,805
JBrowse link
G Rsad2 radical S-adenosyl methionine domain containing 2 decreases expression ISO DDT results in decreased expression of RSAD2 mRNA CTD PMID:25014179 NCBI chr 6:45,655,947...45,669,083
Ensembl chr 6:45,655,954...45,669,148
JBrowse link
G Rsf1 remodeling and spacing factor 1 decreases expression EXP DDT results in decreased expression of RSF1 mRNA CTD PMID:30207508 NCBI chr 1:162,549,222...162,671,962
Ensembl chr 1:162,549,420...162,662,170
JBrowse link
G RT1-Ba RT1 class II, locus Ba decreases methylation EXP DDT results in decreased methylation of RT1-BA gene CTD PMID:30207508 NCBI chr20:4,066,133...4,070,726
Ensembl chr20:4,066,132...4,070,721
JBrowse link
G RT1-Bb RT1 class II, locus Bb decreases methylation EXP DDT results in decreased methylation of RT1-BB gene CTD PMID:30207508 NCBI chr20:4,043,726...4,049,367
Ensembl chr20:4,039,413...4,049,711
JBrowse link
G Runx2 RUNX family transcription factor 2 increases expression ISO DDT results in increased expression of RUNX2 mRNA CTD PMID:25014179 NCBI chr 9:18,564,743...18,773,092
Ensembl chr 9:18,564,927...18,773,092
JBrowse link
G Rxrb retinoid X receptor beta increases activity ISO DDT analog results in increased activity of RXRB protein CTD PMID:18207673 NCBI chr20:3,822,673...3,829,138
Ensembl chr20:3,823,042...3,829,140
JBrowse link
G Ryr1 ryanodine receptor 1 affects activity ISO DDT affects the activity of RYR1 protein CTD PMID:31127943 NCBI chr 1:87,959,596...88,066,252
Ensembl chr 1:87,959,712...88,066,101
JBrowse link
G S1pr1 sphingosine-1-phosphate receptor 1 decreases expression EXP DDT results in decreased expression of S1PR1 mRNA CTD PMID:30207508 NCBI chr 2:218,654,406...218,658,761
Ensembl chr 2:218,654,554...218,658,761
JBrowse link
G Sacs sacsin molecular chaperone decreases expression EXP DDT results in decreased expression of SACS mRNA CTD PMID:30207508 NCBI chr15:41,448,078...41,530,412
Ensembl chr15:41,448,064...41,530,398
JBrowse link
G Sarnp SAP domain containing ribonucleoprotein decreases expression EXP DDT results in decreased expression of SARNP mRNA CTD PMID:30207508 NCBI chr 7:3,246,220...3,300,467
Ensembl chr 7:3,246,220...3,300,455
JBrowse link
G Scarb1 scavenger receptor class B, member 1 increases expression EXP DDT results in increased expression of SCARB1 mRNA CTD PMID:30207508 NCBI chr12:36,694,952...36,761,445
Ensembl chr12:36,694,960...36,761,455
JBrowse link
G Selenop selenoprotein P increases expression EXP DDT results in increased expression of SELENOP mRNA CTD PMID:30207508 NCBI chr 2:53,105,912...53,116,198
Ensembl chr 2:53,109,684...53,114,858
JBrowse link
G Sema4f ssemaphorin 4F increases methylation EXP DDT results in increased methylation of SEMA4F gene CTD PMID:30207508 NCBI chr 4:113,738,225...113,764,532
Ensembl chr 4:113,738,226...113,764,532
JBrowse link
G Sema5a semaphorin 5A decreases expression EXP DDT results in decreased expression of SEMA5A mRNA CTD PMID:30207508 NCBI chr 2:85,377,318...85,808,970
Ensembl chr 2:85,377,318...85,808,970
JBrowse link
G Serpinb5 serpin family B member 5 multiple interactions ISO [DDT results in increased activity of ESR1 protein] which results in increased expression of SERPINB5 mRNA CTD PMID:22403704 NCBI chr13:26,903,052...26,923,250
Ensembl chr13:26,903,052...26,923,250
JBrowse link
G Sesn3 sestrin 3 decreases expression EXP DDT results in decreased expression of SESN3 mRNA CTD PMID:30207508 NCBI chr 8:12,823,060...12,878,749
Ensembl chr 8:12,823,155...12,872,705
JBrowse link
G Setd2 SET domain containing 2, histone lysine methyltransferase decreases expression EXP DDT results in decreased expression of SETD2 mRNA CTD PMID:30207508 NCBI chr 8:118,802,478...118,888,224
Ensembl chr 8:118,803,075...118,888,224
JBrowse link
G Setx senataxin decreases expression EXP DDT results in decreased expression of SETX mRNA CTD PMID:30207508 NCBI chr 3:7,680,430...7,731,815
Ensembl chr 3:7,686,503...7,730,539
JBrowse link
G Sgip1 SH3GL interacting endocytic adaptor 1 increases methylation EXP DDT results in increased methylation of SGIP1 gene CTD PMID:30207508 NCBI chr 5:122,300,415...122,498,478
Ensembl chr 5:122,390,522...122,491,203
JBrowse link
G Shbg sex hormone binding globulin multiple interactions EXP DDT analog inhibits the reaction [Dihydrotestosterone binds to SHBG protein]; DDT inhibits the reaction [Dihydrotestosterone binds to SHBG protein] CTD PMID:9171990 NCBI chr10:56,219,861...56,237,354
Ensembl chr10:56,219,858...56,223,245
JBrowse link
G Shc4 SHC adaptor protein 4 increases methylation EXP DDT results in increased methylation of SHC4 gene CTD PMID:30207508 NCBI chr 3:117,897,738...117,990,289
Ensembl chr 3:117,897,738...117,990,289
JBrowse link
G Shcbp1 SHC binding and spindle associated 1 decreases expression ISO DDT results in decreased expression of SHCBP1 mRNA CTD PMID:25014179 NCBI chr16:90,613,826...90,642,683
Ensembl chr16:90,613,870...90,641,420
JBrowse link
G Slc10a1 solute carrier family 10 member 1 decreases expression ISO DDT results in decreased expression of SLC10A1 mRNA CTD PMID:24464585 NCBI chr 6:104,617,730...104,631,355
Ensembl chr 6:104,617,730...104,631,355
JBrowse link
G Slc12a2 solute carrier family 12 member 2 multiple interactions ISO [o,p'-DDT co-treated with DDT] results in increased expression of SLC12A2 mRNA CTD PMID:27325568 NCBI chr18:52,917,124...52,985,281
Ensembl chr18:52,917,124...52,985,261
JBrowse link
G Slc18a2 solute carrier family 18 member A2 multiple interactions ISO DDT inhibits the reaction [SLC18A2 protein results in increased uptake of Dopamine] CTD PMID:18533268 NCBI chr 1:280,397,831...280,457,968
Ensembl chr 1:280,423,079...280,457,148
JBrowse link
G Slc2a1 solute carrier family 2 member 1 multiple interactions
increases expression
ISO 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [DDT results in increased expression of SLC2A1 mRNA]; Acetylcysteine inhibits the reaction [DDT results in increased expression of SLC2A1 mRNA]; PKM protein alternative form affects the reaction [DDT results in increased expression of SLC2A1 mRNA] CTD PMID:31724279 NCBI chr 5:138,154,677...138,182,897
Ensembl chr 5:138,154,673...138,182,897
JBrowse link
G Slc2a4 solute carrier family 2 member 4 increases expression
decreases expression
ISO
EXP
DDT results in increased expression of SLC2A4 mRNA
DDT results in decreased expression of SLC2A4 protein
CTD PMID:25014179, PMID:31923579 NCBI chr10:56,552,921...56,558,562
Ensembl chr10:56,552,983...56,558,487
JBrowse link
G Slc6a3 solute carrier family 6 member 3 multiple interactions ISO DDT inhibits the reaction [DAT protein results in increased uptake of Dopamine] CTD PMID:18533268 NCBI chr 1:32,323,011...32,363,983
Ensembl chr 1:32,321,580...32,363,983
JBrowse link
G Slc7a11 solute carrier family 7 member 11 increases expression ISO DDT results in increased expression of SLC7A11 mRNA CTD PMID:26198647 NCBI chr 2:139,453,774...139,528,479
Ensembl chr 2:139,453,774...139,528,162
JBrowse link
G Slc8a1 solute carrier family 8 member A1 multiple interactions ISO [o,p'-DDT co-treated with DDT] results in increased expression of SLC8A1 mRNA CTD PMID:27325568 NCBI chr 6:4,244,076...4,564,262
Ensembl chr 6:4,258,991...4,520,604
JBrowse link
G Slc9a1 solute carrier family 9 member A1 multiple interactions ISO [o,p'-DDT co-treated with DDT] results in increased expression of SLC9A1 mRNA CTD PMID:27325568 NCBI chr 5:151,573,122...151,626,360
Ensembl chr 5:151,573,092...151,627,316
JBrowse link
G Slc9a2 solute carrier family 9 member A2 multiple interactions ISO [o,p'-DDT co-treated with DDT] results in increased expression of SLC9A2 mRNA CTD PMID:27325568 NCBI chr 9:47,386,581...47,491,813
Ensembl chr 9:47,386,626...47,491,907
JBrowse link
G Slc9a3 solute carrier family 9 member A3 multiple interactions ISO [o,p'-DDT co-treated with DDT] results in increased expression of SLC9A3 mRNA CTD PMID:27325568 NCBI chr 1:31,731,652...31,777,144
Ensembl chr 1:31,734,327...31,777,070
JBrowse link
G Snhg11 small nucleolar RNA host gene 11 increases expression ISO DDT results in increased expression of SNHG11 mRNA CTD PMID:25014179 NCBI chr 3:154,862,717...154,870,691
Ensembl chr 3:154,863,072...154,869,460
JBrowse link
G Sod1 superoxide dismutase 1 multiple interactions EXP [Polychlorinated Biphenyls co-treated with Dichlorodiphenyl Dichloroethylene co-treated with Dichlorodiphenyldichloroethane co-treated with DDT co-treated with Chlordan co-treated with nonachlor] inhibits the reaction [Fish Oils results in increased expression of SOD1 mRNA] CTD PMID:28659405 NCBI chr11:30,363,282...30,368,858
Ensembl chr11:30,363,280...30,368,862
JBrowse link
G Sod3 superoxide dismutase 3 increases expression EXP DDT results in increased expression of SOD3 mRNA CTD PMID:30207508 NCBI chr14:60,958,583...60,971,143
Ensembl chr14:60,958,592...60,964,324
JBrowse link
G Sos1 SOS Ras/Rac guanine nucleotide exchange factor 1 multiple interactions ISO DDT promotes the reaction [GRB2 protein binds to SOS1 protein] CTD PMID:9070211 NCBI chr 6:3,105,443...3,182,977
Ensembl chr 6:3,104,861...3,182,996
JBrowse link
G Sparc secreted protein acidic and cysteine rich increases expression ISO DDT results in increased expression of SPARC mRNA CTD PMID:25014179 NCBI chr10:40,742,390...40,764,232
Ensembl chr10:40,742,400...40,764,185
JBrowse link
G Spcs3 signal peptidase complex subunit 3 decreases expression EXP DDT results in decreased expression of SPCS3 mRNA CTD PMID:30207508 NCBI chr16:40,050,862...40,056,296
Ensembl chr16:40,050,734...40,058,822
JBrowse link
G Spp1 secreted phosphoprotein 1 increases expression
decreases expression
ISO
EXP
DDT results in increased expression of SPP1 mRNA
DDT results in decreased expression of SPP1 mRNA
CTD PMID:25014179, PMID:30207508 NCBI chr14:6,673,686...6,679,965
Ensembl chr14:6,673,686...6,679,901
JBrowse link
G Sqstm1 sequestosome 1 increases expression ISO DDT results in increased expression of SQSTM1 mRNA CTD PMID:26198647 NCBI chr10:35,704,728...35,716,316
Ensembl chr10:35,704,730...35,716,294
JBrowse link
G Srebf2 sterol regulatory element binding transcription factor 2 increases methylation EXP DDT results in increased methylation of SREBF2 gene CTD PMID:30207508 NCBI chr 7:123,381,082...123,438,605
Ensembl chr 7:123,381,077...123,438,603
JBrowse link
G Srxn1 sulfiredoxin 1 increases expression ISO DDT results in increased expression of SRXN1 mRNA CTD PMID:26198647 NCBI chr 3:147,608,850...147,614,410
Ensembl chr 3:147,609,095...147,632,801
JBrowse link
G Sspn sarcospan decreases expression EXP DDT results in decreased expression of SSPN mRNA CTD PMID:30207508 NCBI chr 4:180,291,389...180,325,799
Ensembl chr 4:180,291,389...180,324,408
JBrowse link
G Sst somatostatin decreases expression EXP DDT results in decreased expression of SST mRNA CTD PMID:19797855 NCBI chr11:80,358,172...80,359,449
Ensembl chr11:80,358,211...80,359,444
JBrowse link
G ST7 suppression of tumorigenicity 7 increases methylation EXP DDT results in increased methylation of ST7 gene CTD PMID:30207508 NCBI chr 4:45,000,223...45,247,793
Ensembl chr 4:45,000,973...45,247,790
JBrowse link
G St8sia1 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 1 increases methylation EXP DDT results in increased methylation of ST8SIA1 gene CTD PMID:30207508 NCBI chr 4:177,065,266...177,195,942
Ensembl chr 4:177,065,168...177,196,180
JBrowse link
G Stat1 signal transducer and activator of transcription 1 increases phosphorylation ISO DDT results in increased phosphorylation of STAT1 protein CTD PMID:9070211 NCBI chr 9:54,287,540...54,327,958
Ensembl chr 9:54,287,541...54,484,533
JBrowse link
G Stat3 signal transducer and activator of transcription 3 multiple interactions
affects localization
ISO Acetylcysteine inhibits the reaction [DDT results in increased phosphorylation of and results in increased expression of STAT3 protein]; DDT results in increased phosphorylation of and results in increased expression of STAT3 protein; INCB018424 inhibits the reaction [DDT results in increased phosphorylation of STAT3 protein]; WP1066 inhibits the reaction [DDT results in increased phosphorylation of STAT3 protein]
DDT affects the localization of STAT3 protein
CTD PMID:24820114 NCBI chr10:88,790,401...88,842,263
Ensembl chr10:88,790,408...88,842,233
JBrowse link
G Stc1 stanniocalcin 1 decreases expression EXP DDT results in decreased expression of STC1 mRNA CTD PMID:30207508 NCBI chr15:50,891,137...50,901,791
Ensembl chr15:50,891,127...50,903,162
JBrowse link
G Stk11ip serine/threonine kinase 11 interacting protein increases methylation EXP DDT results in increased methylation of STK11IP gene CTD PMID:30207508 NCBI chr 9:82,718,343...82,733,894
Ensembl chr 9:82,718,709...82,734,393
JBrowse link
G Stpg1 sperm-tail PG-rich repeat containing 1 increases methylation EXP DDT results in increased methylation of STPG1 gene CTD PMID:30207508 NCBI chr 5:153,834,263...153,888,510
Ensembl chr 5:153,835,821...153,888,506
JBrowse link
G Stx8 syntaxin 8 increases methylation EXP DDT results in increased methylation of STX8 gene CTD PMID:30207508 NCBI chr10:54,512,922...54,753,302
Ensembl chr10:54,512,983...54,753,302
JBrowse link
G Stxbp6 syntaxin binding protein 6 decreases expression EXP DDT results in decreased expression of STXBP6 mRNA CTD PMID:30207508 NCBI chr 6:65,086,483...65,319,527
Ensembl chr 6:65,089,318...65,319,527
JBrowse link
G Syne2 spectrin repeat containing nuclear envelope protein 2 decreases expression EXP DDT results in decreased expression of SYNE2 mRNA CTD PMID:30207508 NCBI chr 6:98,884,269...99,153,551 JBrowse link
G Taf1d TATA-box binding protein associated factor, RNA polymerase I subunit D increases expression ISO DDT results in increased expression of TAF1D mRNA CTD PMID:25014179 NCBI chr 8:13,861,242...13,871,508
Ensembl chr 8:13,861,459...13,871,354
JBrowse link
G Taf9b TATA-box binding protein associated factor 9b increases methylation EXP DDT results in increased methylation of TAF9B gene CTD PMID:30207508 NCBI chr  X:77,281,234...77,295,238
Ensembl chr  X:77,281,210...77,295,426
JBrowse link
G Tax1bp1 Tax1 binding protein 1 decreases expression EXP DDT results in decreased expression of TAX1BP1 mRNA CTD PMID:30207508 NCBI chr 4:82,776,720...82,832,586
Ensembl chr 4:82,776,746...82,833,773
JBrowse link
G Tbx21 T-box transcription factor 21 decreases methylation EXP DDT results in decreased methylation of TBX21 gene CTD PMID:30207508 NCBI chr10:85,032,799...85,049,331
Ensembl chr10:85,032,799...85,049,331
JBrowse link
G Tdrd7 tudor domain containing 7 decreases expression EXP DDT results in decreased expression of TDRD7 mRNA CTD PMID:30207508 NCBI chr 5:61,557,909...61,631,719
Ensembl chr 5:61,564,864...61,631,710
JBrowse link
G Tet1 tet methylcytosine dioxygenase 1 decreases expression EXP DDT results in decreased expression of TET1 mRNA CTD PMID:30207508 NCBI chr20:27,359,122...27,438,039
Ensembl chr20:27,366,213...27,437,427
JBrowse link
G Tff1 trefoil factor 1 multiple interactions ISO [DDT results in increased activity of ESR1 protein] which results in increased expression of TFF1 mRNA CTD PMID:22403704 NCBI chr20:9,892,124...9,895,984
Ensembl chr20:9,892,124...9,895,984
JBrowse link
G Tgfb1 transforming growth factor, beta 1 multiple interactions EXP DDT inhibits the reaction [TGFB1 protein results in increased activity of CASP3 protein] CTD PMID:10200566 NCBI chr 1:82,480,875...82,497,196
Ensembl chr 1:82,480,195...82,497,199
JBrowse link
G Tgfb3 transforming growth factor, beta 3 increases expression EXP DDT results in increased expression of TGFB3 mRNA CTD PMID:29477483 NCBI chr 6:109,913,757...109,936,217
Ensembl chr 6:109,913,757...109,935,533
JBrowse link
G Thsd7a thrombospondin type 1 domain containing 7A decreases expression EXP DDT results in decreased expression of THSD7A mRNA CTD PMID:30207508 NCBI chr 4:38,658,512...39,103,411
Ensembl chr 4:38,664,066...39,102,807
JBrowse link
G Tie1 tyrosine kinase with immunoglobulin-like and EGF-like domains 1 decreases expression ISO DDT results in decreased expression of TIE1 mRNA CTD PMID:25014179 NCBI chr 5:137,294,544...137,321,116
Ensembl chr 5:137,294,544...137,321,121
JBrowse link
G Tmem107 transmembrane protein 107 increases expression ISO DDT results in increased expression of TMEM107 mRNA CTD PMID:25014179 NCBI chr10:55,653,694...55,656,270
Ensembl chr10:55,653,946...55,656,270
JBrowse link
G Tmem131l transmembrane 131 like increases methylation EXP DDT results in increased methylation of TMEM131L gene CTD PMID:30207508 NCBI chr 2:182,897,332...183,031,273
Ensembl chr 2:182,897,830...183,031,214
JBrowse link
G Tmem245 transmembrane protein 245 decreases expression EXP DDT results in decreased expression of TMEM245 mRNA CTD PMID:30207508 NCBI chr 5:73,909,032...73,986,602
Ensembl chr 5:73,918,747...73,986,373
JBrowse link
G Tmem47 transmembrane protein 47 decreases expression EXP DDT results in decreased expression of TMEM47 mRNA CTD PMID:30207508 NCBI chr  X:48,779,110...48,805,644
Ensembl chr  X:48,779,110...48,805,644
JBrowse link
G Tmx3 thioredoxin-related transmembrane protein 3 decreases expression EXP DDT results in decreased expression of TMX3 mRNA CTD PMID:30207508 NCBI chr18:87,580,227...87,613,481
Ensembl chr18:87,580,424...87,610,390
JBrowse link
G Tnf tumor necrosis factor multiple interactions
increases expression
decreases expression
ISO 13-hydroxy-10-oxo-11-octadecenoic acid inhibits the reaction [DDT results in increased expression of TNF mRNA]; DDT inhibits the reaction [endotoxin, Escherichia coli results in increased expression of TNF protein]; SB 203580 inhibits the reaction [DDT results in increased expression of TNF mRNA]
[DDT co-treated with o,p'-DDT] results in decreased expression of TNF mRNA
DDT metabolite results in decreased expression of TNF mRNA; DDT results in decreased expression of TNF mRNA
CTD PMID:12007859, PMID:15603917, PMID:20865247, PMID:28412309, PMID:31521043 NCBI chr20:5,189,382...5,192,000
Ensembl chr20:5,189,390...5,192,000
JBrowse link
G Tnfrsf11b TNF receptor superfamily member 11B decreases expression EXP DDT results in decreased expression of TNFRSF11B mRNA CTD PMID:30207508 NCBI chr 7:93,798,580...93,826,586
Ensembl chr 7:93,798,545...93,826,665
JBrowse link
G Tnfrsf1a TNF receptor superfamily member 1A decreases expression
increases expression
EXP DDT results in decreased expression of TNFRSF1A mRNA
DDT results in increased expression of TNFRSF1A mRNA
CTD PMID:11948501 NCBI chr 4:157,864,905...157,877,634
Ensembl chr 4:157,864,969...157,877,633
JBrowse link
G Tp53 tumor protein p53 multiple interactions
increases methylation
decreases expression
ISO
EXP
DDT inhibits the reaction [TRP53 protein binds to CDKN1A promoter]
DDT results in increased methylation of TP53 promoter
DDT results in decreased expression of TP53 mRNA; DDT results in decreased expression of TP53 protein
DDT results in decreased expression of TRP53 protein
CTD PMID:23684557, PMID:25410620 NCBI chr10:56,186,299...56,198,449
Ensembl chr10:56,187,020...56,198,449
JBrowse link
G Tp53bp2 tumor protein p53 binding protein, 2 increases methylation EXP DDT results in increased methylation of TP53BP2 gene CTD PMID:30207508 NCBI chr13:100,817,206...100,873,837
Ensembl chr13:100,817,359...100,873,890
JBrowse link
G Tp53inp1 tumor protein p53 inducible nuclear protein 1 decreases expression EXP DDT results in decreased expression of TP53INP1 mRNA; DDT results in decreased expression of TP53INP1 protein CTD PMID:30207508, PMID:30421125 NCBI chr 5:24,402,895...24,419,651
Ensembl chr 5:24,410,863...24,416,888
JBrowse link
G Tpm2 tropomyosin 2 increases expression EXP DDT results in increased expression of TPM2 mRNA CTD PMID:30207508 NCBI chr 5:59,016,616...59,025,971
Ensembl chr 5:59,016,622...59,025,631
JBrowse link
G Tpr translocated promoter region, nuclear basket protein decreases expression EXP DDT results in decreased expression of TPR mRNA CTD PMID:30207508 NCBI chr13:67,611,685...67,672,833
Ensembl chr13:67,611,708...67,672,827
JBrowse link
G Traf2 Tnf receptor-associated factor 2 decreases methylation EXP DDT results in decreased methylation of TRAF2 gene CTD PMID:30207508 NCBI chr 3:2,746,061...2,770,690
Ensembl chr 3:2,746,075...2,770,620
JBrowse link
G Trdmt1 tRNA aspartic acid methyltransferase 1 increases methylation EXP DDT results in increased methylation of TRDMT1 gene CTD PMID:30207508 NCBI chr17:80,824,652...80,859,585
Ensembl chr17:80,826,846...80,860,195
JBrowse link
G Trip11 thyroid hormone receptor interactor 11 decreases expression EXP DDT results in decreased expression of TRIP11 mRNA CTD PMID:30207508 NCBI chr 6:125,741,520...125,812,926
Ensembl chr 6:125,742,796...125,812,517
JBrowse link
G Tsc22d3 TSC22 domain family, member 3 multiple interactions ISO DDT inhibits the reaction [Hydrocortisone results in increased expression of TSC22D3 mRNA] CTD PMID:26647222 NCBI chr  X:111,884,285...111,944,693
Ensembl chr  X:111,884,295...111,887,906
JBrowse link
G Tshr thyroid stimulating hormone receptor decreases localization
decreases activity
multiple interactions
ISO DDT results in decreased localization of TSHR protein
DDT results in decreased activity of TSHR protein
DDT binds to and results in decreased activity of TSHR protein
CTD PMID:14759065, PMID:17062616, PMID:19214582 NCBI chr 6:115,170,290...115,306,871
Ensembl chr 6:115,170,865...115,306,871
JBrowse link
G Tspan14 tetraspanin 14 increases methylation EXP DDT results in increased methylation of TSPAN14 gene CTD PMID:30207508 NCBI chr16:17,538,855...17,595,960
Ensembl chr16:17,538,855...17,595,960
JBrowse link
G Ttr transthyretin decreases expression EXP DDT results in decreased expression of TTR mRNA CTD PMID:19797855 NCBI chr18:15,532,963...15,542,180
Ensembl chr18:15,532,963...15,540,177
JBrowse link
G Tuba3b tubulin, alpha 3B increases methylation EXP DDT results in increased methylation of TUBA3B gene CTD PMID:30207508 NCBI chr 4:179,905,154...179,910,703
Ensembl chr 4:179,905,116...179,910,704
JBrowse link
G Tyms thymidylate synthetase decreases expression ISO DDT results in decreased expression of TYMS mRNA CTD PMID:25014179 NCBI chr 9:121,918,875...121,931,564
Ensembl chr 9:121,918,947...121,931,564
JBrowse link
G Uchl3 ubiquitin C-terminal hydrolase L3 increases expression EXP DDT results in increased expression of UCHL3 mRNA CTD PMID:30207508 NCBI chr15:86,153,624...86,198,127
Ensembl chr15:86,153,628...86,198,127
JBrowse link
G Ugt1a6 UDP glucuronosyltransferase family 1 member A6 decreases expression ISO DDT results in decreased expression of UGT1A6 mRNA CTD PMID:31521043 NCBI chr 9:95,241,609...95,302,822
Ensembl chr 9:95,161,157...95,302,822
JBrowse link
G Usp25 ubiquitin specific peptidase 25 decreases methylation EXP DDT results in decreased methylation of USP25 gene CTD PMID:30207508 NCBI chr11:15,436,080...15,558,646
Ensembl chr11:15,436,269...15,558,646
JBrowse link
G Vegfa vascular endothelial growth factor A multiple interactions
decreases expression
increases expression
ISO 13-hydroxy-10-oxo-11-octadecenoic acid inhibits the reaction [DDT results in increased expression of VEGFA mRNA]; aurapten inhibits the reaction [DDT results in increased expression of VEGFA mRNA]; zerumbone inhibits the reaction [DDT results in increased expression of VEGFA mRNA]
DDT results in decreased expression of VEGFA mRNA
CTD PMID:20865247, PMID:31521043 NCBI chr 9:17,340,341...17,355,681
Ensembl chr 9:17,340,341...17,355,681
JBrowse link
G Vim vimentin increases expression ISO DDT results in increased expression of VIM mRNA; DDT results in increased expression of VIM protein CTD PMID:22902829 NCBI chr17:80,882,715...80,891,200
Ensembl chr17:80,882,666...80,891,212
JBrowse link
G Vmp1 vacuole membrane protein 1 increases expression ISO DDT results in increased expression of VMP1 mRNA CTD PMID:25014179 NCBI chr10:73,901,988...74,001,900
Ensembl chr10:73,902,837...74,001,895
JBrowse link
G Vom2r-ps142 vomeronasal 2 receptor, pseudogene 142 decreases methylation EXP DDT results in decreased methylation of VOM2R-PS142 gene CTD PMID:30207508 NCBI chr16:64,920,258...64,925,312 JBrowse link
G Vrk2 VRK serine/threonine kinase 2 decreases methylation EXP DDT results in decreased methylation of VRK2 gene CTD PMID:30207508 NCBI chr14:110,739,835...110,883,836
Ensembl chr14:110,739,226...110,883,803
JBrowse link
G Vti1a vesicle transport through interaction with t-SNAREs 1A increases methylation EXP DDT results in increased methylation of VTI1A gene CTD PMID:30207508 NCBI chr 1:276,310,072...276,508,635
Ensembl chr 1:276,309,927...276,490,602
JBrowse link
G Vwa5a von Willebrand factor A domain containing 5A increases expression EXP DDT results in increased expression of VWA5A mRNA CTD PMID:30207508 NCBI chr 8:42,442,932...42,476,417
Ensembl chr 8:42,443,442...42,466,907
Ensembl chr 3:42,443,442...42,466,907
JBrowse link
G Wfikkn2 WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 2 decreases expression EXP DDT results in decreased expression of WFIKKN2 mRNA CTD PMID:30207508 NCBI chr10:81,936,156...81,943,142
Ensembl chr10:81,936,444...81,942,188
JBrowse link
G Wsb1 WD repeat and SOCS box-containing 1 increases expression ISO DDT results in increased expression of WSB1 mRNA CTD PMID:25014179 NCBI chr10:66,586,905...66,602,984
Ensembl chr10:66,586,924...66,602,987
JBrowse link
G Xdh xanthine dehydrogenase decreases expression EXP DDT results in decreased expression of XDH mRNA CTD PMID:30207508 NCBI chr 6:25,149,570...25,211,273
Ensembl chr 6:25,149,235...25,211,494
JBrowse link
G Zbtb20 zinc finger and BTB domain containing 20 decreases expression EXP DDT results in decreased expression of ZBTB20 mRNA CTD PMID:30207508 NCBI chr11:62,014,925...62,561,113
Ensembl chr11:62,014,925...62,451,184
JBrowse link
G Zc3h18 zinc finger CCCH-type containing 18 increases methylation EXP DDT results in increased methylation of ZC3H18 gene CTD PMID:30207508 NCBI chr19:55,197,348...55,241,800
Ensembl chr19:55,197,704...55,241,851
JBrowse link
G Zdhhc20 zinc finger DHHC-type palmitoyltransferase 20 decreases expression EXP DDT results in decreased expression of ZDHHC20 mRNA CTD PMID:30207508 NCBI chr15:38,108,886...38,165,765
Ensembl chr15:38,109,301...38,165,746
JBrowse link
G Zfp523 zinc finger protein 523 increases methylation EXP DDT results in increased methylation of ZFP523 gene CTD PMID:30207508 NCBI chr20:7,750,786...7,786,020
Ensembl chr20:7,762,327...7,786,049
JBrowse link
G Zfp608 zinc finger protein 608 decreases expression EXP DDT results in decreased expression of ZFP608 mRNA CTD PMID:30207508 NCBI chr18:49,829,650...49,937,522
Ensembl chr18:49,829,650...49,937,522
JBrowse link
G Zfp704 zinc finger protein 704 decreases expression EXP DDT results in decreased expression of ZFP704 mRNA CTD PMID:30207508 NCBI chr 2:94,377,059...94,559,838
Ensembl chr 2:94,377,072...94,551,529
JBrowse link
G Zfpm2 zinc finger protein, multitype 2 increases methylation ISO DDT results in increased methylation of ZFPM2 gene CTD PMID:30822522 NCBI chr 7:79,471,277...79,964,405
Ensembl chr 7:79,638,046...79,964,405
JBrowse link
G Zpbp zona pellucida binding protein decreases methylation EXP DDT results in decreased methylation of ZPBP gene CTD PMID:30207508 NCBI chr14:91,360,670...91,556,406
Ensembl chr14:91,363,152...91,556,231
JBrowse link
dicofol term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ar androgen receptor affects binding
multiple interactions
ISO Dicofol binds to AR protein
Dicofol inhibits the reaction [Dihydrotestosterone results in increased expression of AR mRNA]; Dicofol inhibits the reaction [Metribolone results in increased activity of AR protein]; Dihydrotestosterone inhibits the reaction [Dicofol results in increased activity of AR protein]
CTD PMID:15064155, PMID:15253041, PMID:18324785, PMID:21310686 NCBI chr  X:67,656,253...67,828,998
Ensembl chr  X:67,656,253...67,829,026
JBrowse link
G Cyp19a1 cytochrome P450, family 19, subfamily a, polypeptide 1 decreases activity ISO Dicofol results in decreased activity of CYP19A1 protein CTD PMID:10806373 NCBI chr 8:58,744,849...58,772,408
Ensembl chr 8:58,744,849...58,772,408
JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 increases expression EXP Dicofol results in increased expression of CYP1A1 mRNA; Dicofol results in increased expression of CYP1A1 protein CTD PMID:19595748 NCBI chr 8:62,472,087...62,478,122
Ensembl chr 8:62,472,095...62,478,147
JBrowse link
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 increases expression EXP Dicofol results in increased expression of CYP1A2 mRNA CTD PMID:19595748 NCBI chr 8:62,451,360...62,458,244
Ensembl chr 8:62,451,329...62,458,301
JBrowse link
G Cyp2b1 cytochrome P450, family 2, subfamily b, polypeptide 1 increases expression EXP Dicofol results in increased expression of CYP2B1 protein CTD PMID:19595748 NCBI chr 7:99,142,431...99,183,540
Ensembl chr 7:99,142,450...99,181,783
JBrowse link
G Cyp2b2 cytochrome P450, family 2, subfamily b, polypeptide 2 increases expression EXP Dicofol results in increased expression of CYP2B2 protein CTD PMID:19595748 NCBI chr 1:83,103,925...83,119,578
Ensembl chr 1:83,103,925...83,119,193
JBrowse link
G Cyp2e1 cytochrome P450, family 2, subfamily e, polypeptide 1 increases expression EXP Dicofol results in increased expression of CYP2E1 protein CTD PMID:19595748 NCBI chr 1:213,511,892...213,522,195
Ensembl chr 1:213,511,874...213,535,542
JBrowse link
G Cyp3a23-3a1 cytochrome P450, family 3, subfamily a, polypeptide 23-polypeptide 1 increases expression EXP Dicofol results in increased expression of CYP3A23-3A1 mRNA CTD PMID:19595748 NCBI chr12:11,053,888...11,082,742
Ensembl chr12:11,655,402...11,733,136
JBrowse link
G Dio1 iodothyronine deiodinase 1 decreases activity ISO Dicofol results in decreased activity of DIO1 protein CTD PMID:29228274 NCBI chr 5:126,894,837...126,911,532
Ensembl chr 5:126,895,286...126,911,520
JBrowse link
G Esr1 estrogen receptor 1 affects binding
multiple interactions
increases activity
ISO Dicofol binds to ESR1 protein
Dicofol binds to and results in increased activity of ESR1 protein
Dicofol results in increased activity of ESR1 protein
CTD PMID:10789375, PMID:15064155, PMID:15253041, PMID:16337670, PMID:29162470 NCBI chr 1:41,192,029...41,594,799
Ensembl chr 1:41,192,824...41,594,796
JBrowse link
G Esr2 estrogen receptor 2 increases activity ISO Dicofol results in increased activity of ESR2 protein CTD PMID:15064155 NCBI chr 6:99,163,953...99,214,711
Ensembl chr 6:99,164,357...99,214,251
JBrowse link
G Ggt1 gamma-glutamyltransferase 1 increases activity EXP Dicofol results in increased activity of GGT1 protein CTD PMID:2387028 NCBI chr20:14,019,723...14,045,781
Ensembl chr20:14,019,723...14,025,068
JBrowse link
G Gpt glutamic--pyruvic transaminase increases activity EXP Dicofol results in increased activity of GPT protein CTD PMID:2387028 NCBI chr 7:117,759,083...117,761,932
Ensembl chr 7:117,759,083...117,761,931
JBrowse link
G Ifnb1 interferon beta 1 multiple interactions ISO Dicofol inhibits the reaction [Lipopolysaccharides results in increased expression of IFNB1 mRNA] CTD PMID:18177342 NCBI chr 5:106,865,192...106,865,746
Ensembl chr 5:106,865,192...106,865,746
JBrowse link
G Nfkb1 nuclear factor kappa B subunit 1 multiple interactions ISO Dicofol inhibits the reaction [Lipopolysaccharides results in increased activity of NFKB1 protein] CTD PMID:17015962 NCBI chr 2:240,773,520...240,890,053
Ensembl chr 2:240,773,456...240,866,689
JBrowse link
G Nr1i2 nuclear receptor subfamily 1, group I, member 2 multiple interactions ISO Dicofol binds to and results in increased activity of NR1I2 protein CTD PMID:21115097 NCBI chr11:65,022,100...65,058,546
Ensembl chr11:65,022,100...65,058,545
JBrowse link
G Nr1i3 nuclear receptor subfamily 1, group I, member 3 increases activity ISO Dicofol results in increased activity of NR1I3 protein CTD PMID:28927721 NCBI chr13:89,585,072...89,591,278
Ensembl chr13:89,586,283...89,591,277
JBrowse link
G Prkcb protein kinase C, beta multiple interactions
increases activity
ISO Calcium inhibits the reaction [Dicofol results in increased activity of PRKCB protein]; Phosphatidylserines promotes the reaction [Dicofol results in increased activity of PRKCB protein] CTD PMID:1724372 NCBI chr 1:192,233,569...192,575,339
Ensembl chr 1:192,233,910...192,574,831
JBrowse link
G Ttr transthyretin affects binding EXP Dicofol binds to TTR protein CTD PMID:2043046 NCBI chr18:15,532,963...15,542,180
Ensembl chr18:15,532,963...15,540,177
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19816
    role 19764
      biological role 19764
        aetiopathogenetic role 18960
          carcinogenic agent 18331
            DDT 533
              2,3-dihydroxy-DDT + 0
              dicofol 19
Path 2
Term Annotations click to browse term
  CHEBI ontology 19816
    subatomic particle 19814
      composite particle 19814
        hadron 19814
          baryon 19814
            nucleon 19814
              atomic nucleus 19814
                atom 19814
                  main group element atom 19702
                    p-block element atom 19702
                      carbon group element atom 19608
                        carbon atom 19597
                          organic molecular entity 19597
                            organic molecule 19522
                              organic cyclic compound 19320
                                carbocyclic compound 18222
                                  benzenoid aromatic compound 17254
                                    benzenes 17010
                                      chlorobenzenes 13342
                                        monochlorobenzenes 9524
                                          4,4'-dichlorodiphenylmethane 534
                                            DDT 533
                                              2,3-dihydroxy-DDT + 0
                                              dicofol 19
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.