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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:1,2-diacyl-sn-glycero-3-phosphocholine(1+)
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Accession:CHEBI:16110 term browser browse the term
Definition:A phosphatidylcholine that is a glycerol phosphatide (phosphoglyceride, glycerophospholipid) in which the hydroxy group of choline is esterified with the phosphate group of phosphatidic acid.
Synonyms:related_synonym: (3-sn-phosphatidyl)choline;   1,2-Diacyl-sn-glycero-3-phosphocholine;   1,2-diacyl-sn-glycero-3-phosphocholines;   Choline phosphatide;   Formula=C10H19NO8PR2;   L-alpha-phosphatidylcholine;   Lecithin;   PC;   Phosphatidyl-N-trimethylethanolamine;   Phosphatidylcholine;   SMILES=C[N+](C)(C)CCOP(O)(=O)OC[C@@H](COC([*])=O)OC([*])=O;   lecithins
 alt_id: CHEBI:11148;   CHEBI:11753;   CHEBI:1681;   CHEBI:18878;   CHEBI:20200;   CHEBI:23660;   CHEBI:26029;   CHEBI:44694;   CHEBI:8128
 xref: CAS:8002-43-5;   KEGG:C00157;   PDBeChem:PC1;   PMID:16341241;   PMID:3196084;   PMID:7192727
 cyclic_relationship: is_conjugate_acid_of CHEBI:57643


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1,2-dilauroyl-sn-glycero-3-phosphocholine(1+) term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cyp3a2 cytochrome P450, family 3, subfamily a, polypeptide 2 multiple interactions EXP [1,2-dilauroylphosphatidylcholine co-treated with 1,2-oleoylphosphatidylcholine co-treated with Phosphatidylserines co-treated with Sodium Cholate] results in increased activity of CYP3A2 protein CTD PMID:1627548 NCBI chr12:11,641,500...11,677,818
Ensembl chr12:11,655,402...11,733,136
JBrowse link
G Cyp3a62 cytochrome P450, family 3, subfamily a, polypeptide 62 multiple interactions ISO [1,2-dilauroylphosphatidylcholine co-treated with 1,2-oleoylphosphatidylcholine co-treated with Phosphatidylserines co-treated with Sodium Cholate] results in increased activity of CYP3A4 protein CTD PMID:1627548 NCBI chr12:18,679,809...18,709,397
Ensembl chr12:18,678,594...18,709,397
JBrowse link
G Nr5a2 nuclear receptor subfamily 5, group A, member 2 increases expression ISO 1,2-dilauroylphosphatidylcholine results in increased expression of NR5A2 CTD PMID:24459144 NCBI chr13:53,750,470...53,870,288
Ensembl chr13:53,750,473...53,870,428
JBrowse link
G Pon1 paraoxonase 1 increases activity ISO 1,2-dilauroylphosphatidylcholine results in increased activity of PON1 protein CTD PMID:12963475 NCBI chr 4:30,249,749...30,276,297
Ensembl chr 4:30,249,742...30,276,372
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19841
    role 19792
      application 19465
        pharmaceutical 19338
          drug 19338
            1,2-diacyl-sn-glycero-3-phosphocholine(1+) 4
              1,2-di-O-[1-(14)C]-palmitoyl-sn-glycero-3-phosphocholine 0
              1,2-di-O-palmitoyl-sn-glycero-3-phosphocholine 0
              1,2-dicaproyl-sn-glycero-3-phosphocholine 0
              1,2-dilauroyl-sn-glycero-3-phosphocholine(1+) 4
              1,2-dioleoyl-sn-glycero-3-phosphocholine(1+) 0
              1-O-caproyl-2-O-(5-oxovaleryl)-sn-glycero-3-phosphocholine 0
              1-O-dodecanoyl-2-O-pentacosanoyl-sn-glycero-3-phosphocholine 0
              1-O-palmitoyl-2-O-(5-oxovaleryl)-sn-glycero-3-phosphocholine(1+) 0
              1-O-palmitoyl-2-O-(epoxyisoprostanoyl)-sn-glycero-3-phosphocholine 0
              1-acyl-2-[(S)-12-hydroxyoleoyl]-sn-glycero-3-phosphocholine(1+) 0
              1-acyl-2-linoleoyl-sn-glycero-3-phosphocholine + 0
              1-acyl-2-oleoyl-sn-glycero-3-phosphocholine 0
              1-acyl-2-oleoyl-sn-glycero-3-phosphocholines 0
              1-hexadecanoyl-2-\{12-[(7-nitro-2,1,3-benzoxadiazol-4-yl)amino]dodecanoyl\}-sn-glycero-3-phosphocholine 0
              1-hexadecanoyl-2-\{6-[(7-nitro-2,1,3-benzoxadiazol-4-yl)amino]hexanoyl\}-sn-glycero-3-phosphocholine 0
              1-stearoyl-2-oleoyl-sn-glycero-3-phosphocholine(1+) 0
              2-acyl-1-linoleoyl-sn-glycero-3-phosphocholine 0
              2-acyl-1-oleoyl-sn-glycero-3-phosphocholine 0
              2-acyl-1-palmitoyl-sn-glycero-3-phosphocholine + 0
              \{1-hexadecanoyl-2-[(Z)-octadec-9-enoyl]-sn-glycero-3-phospho\}choline 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19841
    subatomic particle 19839
      composite particle 19839
        hadron 19839
          baryon 19839
            nucleon 19839
              atomic nucleus 19839
                atom 19839
                  main group element atom 19732
                    main group molecular entity 19732
                      s-block molecular entity 19481
                        hydrogen molecular entity 19473
                          hydrides 18745
                            inorganic hydride 17483
                              pnictogen hydride 17456
                                nitrogen hydride 17300
                                  ammonium 8230
                                    ammonium ion derivative 8226
                                      quaternary ammonium ion 5094
                                        phosphatidylcholine(1+) 5
                                          1,2-diacyl-sn-glycero-3-phosphocholine(1+) 4
                                            1,2-di-O-[1-(14)C]-palmitoyl-sn-glycero-3-phosphocholine 0
                                            1,2-di-O-palmitoyl-sn-glycero-3-phosphocholine 0
                                            1,2-dicaproyl-sn-glycero-3-phosphocholine 0
                                            1,2-dilauroyl-sn-glycero-3-phosphocholine(1+) 4
                                            1,2-dioleoyl-sn-glycero-3-phosphocholine(1+) 0
                                            1-O-caproyl-2-O-(5-oxovaleryl)-sn-glycero-3-phosphocholine 0
                                            1-O-dodecanoyl-2-O-pentacosanoyl-sn-glycero-3-phosphocholine 0
                                            1-O-palmitoyl-2-O-(5-oxovaleryl)-sn-glycero-3-phosphocholine(1+) 0
                                            1-O-palmitoyl-2-O-(epoxyisoprostanoyl)-sn-glycero-3-phosphocholine 0
                                            1-acyl-2-[(S)-12-hydroxyoleoyl]-sn-glycero-3-phosphocholine(1+) 0
                                            1-acyl-2-linoleoyl-sn-glycero-3-phosphocholine + 0
                                            1-acyl-2-oleoyl-sn-glycero-3-phosphocholine 0
                                            1-acyl-2-oleoyl-sn-glycero-3-phosphocholines 0
                                            1-hexadecanoyl-2-\{12-[(7-nitro-2,1,3-benzoxadiazol-4-yl)amino]dodecanoyl\}-sn-glycero-3-phosphocholine 0
                                            1-hexadecanoyl-2-\{6-[(7-nitro-2,1,3-benzoxadiazol-4-yl)amino]hexanoyl\}-sn-glycero-3-phosphocholine 0
                                            1-stearoyl-2-oleoyl-sn-glycero-3-phosphocholine(1+) 0
                                            2-acyl-1-linoleoyl-sn-glycero-3-phosphocholine 0
                                            2-acyl-1-oleoyl-sn-glycero-3-phosphocholine 0
                                            2-acyl-1-palmitoyl-sn-glycero-3-phosphocholine + 0
                                            \{1-hexadecanoyl-2-[(Z)-octadec-9-enoyl]-sn-glycero-3-phospho\}choline 0
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