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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:1,2-diacyl-sn-glycero-3-phosphocholine(1+)
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Accession:CHEBI:16110 term browser browse the term
Definition:A phosphatidylcholine that is a glycerol phosphatide (phosphoglyceride, glycerophospholipid) in which the hydroxy group of choline is esterified with the phosphate group of phosphatidic acid.
Synonyms:related_synonym: (3-sn-phosphatidyl)choline;   1,2-Diacyl-sn-glycero-3-phosphocholine;   1,2-diacyl-sn-glycero-3-phosphocholines;   Choline phosphatide;   Formula=C10H19NO8PR2;   L-alpha-phosphatidylcholine;   Lecithin;   PC;   Phosphatidyl-N-trimethylethanolamine;   Phosphatidylcholine;   SMILES=C[N+](C)(C)CCOP(O)(=O)OC[C@@H](COC([*])=O)OC([*])=O;   lecithins
 alt_id: CHEBI:11148;   CHEBI:11753;   CHEBI:1681;   CHEBI:18878;   CHEBI:20200;   CHEBI:23660;   CHEBI:26029;   CHEBI:44694;   CHEBI:8128
 xref: CAS:8002-43-5;   KEGG:C00157;   PDBeChem:PC1;   PMID:16341241;   PMID:3196084;   PMID:7192727
 cyclic_relationship: is_conjugate_acid_of CHEBI:57643


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1,2-dilauroyl-sn-glycero-3-phosphocholine(1+) term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cyp3a2 cytochrome P450, family 3, subfamily a, polypeptide 2 multiple interactions EXP
ISO		 [1,2-dilauroylphosphatidylcholine co-treated with 1,2-oleoylphosphatidylcholine co-treated with Phosphatidylserines co-treated with Sodium Cholate] results in increased activity of CYP3A2 protein
[1,2-dilauroylphosphatidylcholine co-treated with 1,2-oleoylphosphatidylcholine co-treated with Phosphatidylserines co-treated with Sodium Cholate] results in increased activity of CYP3A4 protein		 CTD PMID:1627548 NCBI chr12:9,207,978...9,230,064
Ensembl chr12:9,015,383...9,285,008 		JBrowse link
G Nr5a2 nuclear receptor subfamily 5, group A, member 2 increases expression ISO 1,2-dilauroylphosphatidylcholine results in increased expression of NR5A2 CTD PMID:24459144 NCBI chr13:48,313,634...48,433,494
Ensembl chr13:48,316,301...48,433,326 		JBrowse link
G Pon1 paraoxonase 1 increases activity ISO 1,2-dilauroylphosphatidylcholine results in increased activity of PON1 protein CTD PMID:12963475 NCBI chr 4:33,294,737...33,325,759
Ensembl chr 4:33,294,722...33,321,360 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19900
    role 19875
      application 19710
        pharmaceutical 19536
          drug 19536
            1,2-diacyl-sn-glycero-3-phosphocholine(1+) 3
              1,2-di-O-[1-(14)C]-palmitoyl-sn-glycero-3-phosphocholine 0
              1,2-di-O-palmitoyl-sn-glycero-3-phosphocholine 0
              1,2-dicaproyl-sn-glycero-3-phosphocholine 0
              1,2-dilauroyl-sn-glycero-3-phosphocholine(1+) 3
              1,2-dioleoyl-sn-glycero-3-phosphocholine(1+) 0
              1-O-caproyl-2-O-(5-oxovaleryl)-sn-glycero-3-phosphocholine 0
              1-O-dodecanoyl-2-O-pentacosanoyl-sn-glycero-3-phosphocholine 0
              1-O-palmitoyl-2-O-(5-oxovaleryl)-sn-glycero-3-phosphocholine(1+) 0
              1-O-palmitoyl-2-O-(epoxyisoprostanoyl)-sn-glycero-3-phosphocholine 0
              1-acyl-2-[(S)-12-hydroxyoleoyl]-sn-glycero-3-phosphocholine(1+) 0
              1-acyl-2-linoleoyl-sn-glycero-3-phosphocholine + 0
              1-acyl-2-oleoyl-sn-glycero-3-phosphocholine 0
              1-acyl-2-oleoyl-sn-glycero-3-phosphocholines 0
              1-hexadecanoyl-2-\{12-[(7-nitro-2,1,3-benzoxadiazol-4-yl)amino]dodecanoyl\}-sn-glycero-3-phosphocholine 0
              1-hexadecanoyl-2-\{6-[(7-nitro-2,1,3-benzoxadiazol-4-yl)amino]hexanoyl\}-sn-glycero-3-phosphocholine 0
              1-stearoyl-2-oleoyl-sn-glycero-3-phosphocholine(1+) 0
              2-acyl-1-linoleoyl-sn-glycero-3-phosphocholine 0
              2-acyl-1-oleoyl-sn-glycero-3-phosphocholine 0
              2-acyl-1-palmitoyl-sn-glycero-3-phosphocholine + 0
              \{1-hexadecanoyl-2-[(Z)-octadec-9-enoyl]-sn-glycero-3-phospho\}choline 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19900
    subatomic particle 19898
      composite particle 19898
        hadron 19898
          baryon 19898
            nucleon 19898
              atomic nucleus 19898
                atom 19898
                  main group element atom 19845
                    main group molecular entity 19845
                      s-block molecular entity 19678
                        hydrogen molecular entity 19667
                          hydrides 19146
                            inorganic hydride 18124
                              pnictogen hydride 18112
                                nitrogen hydride 18017
                                  ammonium 8312
                                    ammonium ion derivative 8307
                                      quaternary ammonium ion 5268
                                        phosphatidylcholine(1+) 5
                                          1,2-diacyl-sn-glycero-3-phosphocholine(1+) 3
                                            1,2-di-O-[1-(14)C]-palmitoyl-sn-glycero-3-phosphocholine 0
                                            1,2-di-O-palmitoyl-sn-glycero-3-phosphocholine 0
                                            1,2-dicaproyl-sn-glycero-3-phosphocholine 0
                                            1,2-dilauroyl-sn-glycero-3-phosphocholine(1+) 3
                                            1,2-dioleoyl-sn-glycero-3-phosphocholine(1+) 0
                                            1-O-caproyl-2-O-(5-oxovaleryl)-sn-glycero-3-phosphocholine 0
                                            1-O-dodecanoyl-2-O-pentacosanoyl-sn-glycero-3-phosphocholine 0
                                            1-O-palmitoyl-2-O-(5-oxovaleryl)-sn-glycero-3-phosphocholine(1+) 0
                                            1-O-palmitoyl-2-O-(epoxyisoprostanoyl)-sn-glycero-3-phosphocholine 0
                                            1-acyl-2-[(S)-12-hydroxyoleoyl]-sn-glycero-3-phosphocholine(1+) 0
                                            1-acyl-2-linoleoyl-sn-glycero-3-phosphocholine + 0
                                            1-acyl-2-oleoyl-sn-glycero-3-phosphocholine 0
                                            1-acyl-2-oleoyl-sn-glycero-3-phosphocholines 0
                                            1-hexadecanoyl-2-\{12-[(7-nitro-2,1,3-benzoxadiazol-4-yl)amino]dodecanoyl\}-sn-glycero-3-phosphocholine 0
                                            1-hexadecanoyl-2-\{6-[(7-nitro-2,1,3-benzoxadiazol-4-yl)amino]hexanoyl\}-sn-glycero-3-phosphocholine 0
                                            1-stearoyl-2-oleoyl-sn-glycero-3-phosphocholine(1+) 0
                                            2-acyl-1-linoleoyl-sn-glycero-3-phosphocholine 0
                                            2-acyl-1-oleoyl-sn-glycero-3-phosphocholine 0
                                            2-acyl-1-palmitoyl-sn-glycero-3-phosphocholine + 0
                                            \{1-hexadecanoyl-2-[(Z)-octadec-9-enoyl]-sn-glycero-3-phospho\}choline 0
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