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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:ethylbenzene
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Accession:CHEBI:16101 term browser browse the term
Definition:An alkylbenzene carrying an ethyl substituent. It is a constituent of coal tar and petroleum.
Synonyms:related_synonym: Aethylbenzol;   Ethylbenzol;   Ethylenzene;   Formula=C8H10;   InChI=1S/C8H10/c1-2-8-6-4-3-5-7-8/h3-7H,2H2,1H3;   InChIKey=YNQLUTRBYVCPMQ-UHFFFAOYSA-N;   Phenylethane;   SMILES=CCc1ccccc1;   alpha-methyltoluene
 alt_id: CHEBI:14229;   CHEBI:23999;   CHEBI:45136;   CHEBI:4898
 xref: Beilstein:1901871;   CAS:100-41-4;   DrugBank:DB01722;   Gmelin:2990;   HMDB:HMDB0059905;   KEGG:C07111
 xref_mesh: MESH:C004912
 xref: MetaCyc:ETHYLBENZENE;   Reaxys:1901871;   UM-BBD_compID:c0116;   Wikipedia:Ethylbenzene


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ethylbenzene term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACE angiotensin I converting enzyme multiple interactions EXP [Toluene co-treated with ethylbenzene co-treated with Xylenes] results in decreased methylation of ACE gene; [Toluene co-treated with ethylbenzene co-treated with Xylenes] results in increased expression of ACE mRNA CTD PMID:26018793 NCBI chr17:63,477,061...63,498,373
Ensembl chr17:63,477,061...63,498,380
JBrowse link
G ACHE acetylcholinesterase (Cartwright blood group) decreases expression ISO ethylbenzene results in decreased expression of ACHE protein CTD PMID:21241565 NCBI chr 7:100,889,994...100,896,994
Ensembl chr 7:100,889,994...100,896,974
JBrowse link
G BAX BCL2 associated X, apoptosis regulator decreases expression
increases expression
ISO ethylbenzene results in decreased expression of BAX protein
ethylbenzene results in increased expression of BAX mRNA; ethylbenzene results in increased expression of BAX protein
CTD PMID:20137408 PMID:20156836 PMID:21241565 PMID:25518993 NCBI chr19:48,954,825...48,961,798
Ensembl chr19:48,954,815...48,961,798
JBrowse link
G BCL2 BCL2 apoptosis regulator decreases expression ISO ethylbenzene results in decreased expression of BCL2 mRNA; ethylbenzene results in decreased expression of BCL2 protein CTD PMID:20137408 PMID:20156836 PMID:21241565 PMID:25518993 NCBI chr18:63,123,346...63,320,280
Ensembl chr18:63,123,346...63,320,128
JBrowse link
G BCL2A1 BCL2 related protein A1 increases expression EXP ethylbenzene results in increased expression of BCL2A1 mRNA CTD PMID:20359517 NCBI chr15:79,960,892...79,971,196
Ensembl chr15:79,960,892...79,971,196
JBrowse link
G BCL6 BCL6 transcription repressor increases expression EXP ethylbenzene results in increased expression of BCL6 mRNA CTD PMID:20359517 NCBI chr 3:187,721,377...187,745,472
Ensembl chr 3:187,721,377...187,745,725
JBrowse link
G BIRC3 baculoviral IAP repeat containing 3 increases expression EXP ethylbenzene results in increased expression of BIRC3 mRNA CTD PMID:20359517 NCBI chr11:102,317,373...102,339,403
Ensembl chr11:102,317,450...102,339,403
JBrowse link
G BMP8B bone morphogenetic protein 8b multiple interactions EXP [Toluene co-treated with ethylbenzene co-treated with Xylenes] results in decreased expression of BMP8B mRNA; [Toluene co-treated with ethylbenzene co-treated with Xylenes] results in increased methylation of BMP8B gene CTD PMID:26018793 NCBI chr 1:39,757,182...39,788,865
Ensembl chr 1:39,757,182...39,788,865
JBrowse link
G BTG1 BTG anti-proliferation factor 1 increases expression EXP ethylbenzene results in increased expression of BTG1 mRNA CTD PMID:20359517 NCBI chr12:92,140,278...92,145,846
Ensembl chr12:92,140,278...92,145,846
JBrowse link
G CARMIL3 capping protein regulator and myosin 1 linker 3 multiple interactions EXP [Toluene co-treated with ethylbenzene co-treated with Xylenes] results in decreased methylation of CARMIL3 gene; [Toluene co-treated with ethylbenzene co-treated with Xylenes] results in increased expression of CARMIL3 mRNA CTD PMID:26018793 NCBI chr14:24,052,009...24,069,729
Ensembl chr14:24,052,009...24,069,729
JBrowse link
G CASP3 caspase 3 increases expression ISO ethylbenzene results in increased expression of CASP3 mRNA; ethylbenzene results in increased expression of CASP3 protein CTD PMID:20137408 PMID:20156836 PMID:21241565 PMID:25518993 NCBI chr 4:184,627,696...184,649,447
Ensembl chr 4:184,627,696...184,649,509
JBrowse link
G CASP9 caspase 9 increases expression ISO ethylbenzene results in increased expression of CASP9 mRNA; ethylbenzene results in increased expression of CASP9 protein CTD PMID:20137408 PMID:20156836 PMID:21241565 PMID:25518993 NCBI chr 1:15,491,401...15,524,912
Ensembl chr 1:15,490,832...15,526,534
JBrowse link
G CAT catalase decreases activity ISO ethylbenzene results in decreased activity of CAT protein CTD PMID:24053957 NCBI chr11:34,438,934...34,472,060
Ensembl chr11:34,438,934...34,472,060
JBrowse link
G CBLB Cbl proto-oncogene B increases expression ISO ethylbenzene results in increased expression of CBLB mRNA CTD PMID:20955722 NCBI chr 3:105,655,461...105,869,552
Ensembl chr 3:105,655,461...105,869,552
JBrowse link
G CCL5 C-C motif chemokine ligand 5 decreases expression ISO ethylbenzene results in decreased expression of CCL5 mRNA CTD PMID:20955722 NCBI chr17:35,871,491...35,880,360
Ensembl chr17:35,871,491...35,880,793
JBrowse link
G CD37 CD37 molecule decreases expression ISO ethylbenzene results in decreased expression of CD37 mRNA CTD PMID:20955722 NCBI chr19:49,334,961...49,340,608
Ensembl chr19:49,335,171...49,343,335
JBrowse link
G CD38 CD38 molecule increases expression ISO ethylbenzene results in increased expression of CD38 mRNA CTD PMID:20955722 NCBI chr 4:15,778,328...15,853,232
Ensembl chr 4:15,778,275...15,853,232
JBrowse link
G CD4 CD4 molecule increases expression ISO ethylbenzene results in increased expression of CD4 mRNA CTD PMID:20955722 NCBI chr12:6,789,528...6,820,799
Ensembl chr12:6,786,858...6,820,799
JBrowse link
G CD8A CD8a molecule increases expression ISO ethylbenzene results in increased expression of CD8A mRNA CTD PMID:20955722 NCBI chr 2:86,784,605...86,808,396
Ensembl chr 2:86,784,610...86,808,396
JBrowse link
G CDCP2 CUB domain containing protein 2 multiple interactions EXP [Toluene co-treated with ethylbenzene co-treated with Xylenes] results in decreased methylation of CDCP2 gene; [Toluene co-treated with ethylbenzene co-treated with Xylenes] results in increased expression of CDCP2 mRNA CTD PMID:26018793 NCBI chr 1:54,132,687...54,153,181
Ensembl chr 1:54,132,968...54,153,770
JBrowse link
G CHRNA10 cholinergic receptor nicotinic alpha 10 subunit multiple interactions EXP ethylbenzene inhibits the reaction [Acetylcholine results in increased activity of [CHRNA9 protein binds to CHRNA10 protein]] CTD PMID:18602458 NCBI chr11:3,665,587...3,673,629
Ensembl chr11:3,665,587...3,671,384
JBrowse link
G CHRNA9 cholinergic receptor nicotinic alpha 9 subunit multiple interactions EXP ethylbenzene inhibits the reaction [Acetylcholine results in increased activity of [CHRNA9 protein binds to CHRNA10 protein]] CTD PMID:18602458 NCBI chr 4:40,335,333...40,355,217
Ensembl chr 4:40,335,333...40,355,217
JBrowse link
G CIITA class II major histocompatibility complex transactivator increases expression ISO ethylbenzene results in increased expression of CIITA mRNA CTD PMID:20955722 NCBI chr16:10,866,208...10,941,562
Ensembl chr16:10,866,222...10,943,021
JBrowse link
G CLCN4 chloride voltage-gated channel 4 multiple interactions EXP [Toluene co-treated with ethylbenzene co-treated with Xylenes] results in decreased expression of CLCN4 mRNA; [Toluene co-treated with ethylbenzene co-treated with Xylenes] results in increased methylation of CLCN4 gene CTD PMID:26018793 NCBI chr  X:10,156,975...10,237,660
Ensembl chr  X:10,156,975...10,237,660
JBrowse link
G CTH cystathionine gamma-lyase increases expression EXP ethylbenzene results in increased expression of CTH mRNA CTD PMID:20359517 NCBI chr 1:70,411,268...70,441,949
Ensembl chr 1:70,411,218...70,439,851
JBrowse link
G CXCL8 C-X-C motif chemokine ligand 8 increases expression EXP ethylbenzene results in increased expression of CXCL8 mRNA CTD PMID:20359517 NCBI chr 4:73,740,569...73,743,716
Ensembl chr 4:73,740,541...73,743,716
JBrowse link
G CXCR2 C-X-C motif chemokine receptor 2 increases expression ISO ethylbenzene results in increased expression of CXCR2 mRNA CTD PMID:20955722 NCBI chr 2:218,125,294...218,137,253
Ensembl chr 2:218,125,289...218,137,251
JBrowse link
G CXCR4 C-X-C motif chemokine receptor 4 increases expression EXP ethylbenzene results in increased expression of CXCR4 mRNA CTD PMID:20359517 NCBI chr 2:136,114,349...136,118,149
Ensembl chr 2:136,114,349...136,118,149
JBrowse link
G CYCS cytochrome c, somatic increases expression ISO ethylbenzene results in increased expression of CYCS mRNA; ethylbenzene results in increased expression of CYCS protein CTD PMID:20137408 PMID:20156836 PMID:21241565 PMID:25518993 NCBI chr 7:25,118,656...25,125,260
Ensembl chr 7:25,118,656...25,125,260
JBrowse link
G CYP1A1 cytochrome P450 family 1 subfamily A member 1 increases expression
multiple interactions
ISO
EXP
ethylbenzene results in increased expression of CYP1A1 protein
CYP1A1 gene polymorphism affects the susceptibility to [Benzene co-treated with Toluene co-treated with ethylbenzene co-treated with Xylenes]
CTD PMID:8135039 PMID:23138419 NCBI chr15:74,719,542...74,725,528
Ensembl chr15:74,719,542...74,725,536
JBrowse link
G CYP1B1 cytochrome P450 family 1 subfamily B member 1 decreases expression EXP ethylbenzene results in decreased expression of CYP1B1 mRNA CTD PMID:20359517 NCBI chr 2:38,067,509...38,076,151
Ensembl chr 2:38,066,973...38,109,902
JBrowse link
G CYP2E1 cytochrome P450 family 2 subfamily E member 1 multiple interactions
increases expression
ISO ethylbenzene results in increased expression of and results in increased activity of CYP2E1 protein; GH1 protein inhibits the reaction [ethylbenzene results in increased expression of CYP2E1 protein]
ethylbenzene results in increased expression of CYP2E1 mRNA; ethylbenzene results in increased expression of CYP2E1 protein
CTD PMID:1417939 PMID:8517779 PMID:11884239 NCBI chr10:133,527,363...133,539,123
Ensembl chr10:133,520,406...133,561,220
JBrowse link
G DENND5A DENN domain containing 5A increases expression EXP ethylbenzene results in increased expression of DENND5A mRNA CTD PMID:20359517 NCBI chr11:9,138,825...9,265,350
Ensembl chr11:9,138,825...9,265,959
JBrowse link
G DNAJB9 DnaJ heat shock protein family (Hsp40) member B9 increases expression EXP ethylbenzene results in increased expression of DNAJB9 mRNA CTD PMID:20359517 NCBI chr 7:108,569,874...108,574,850
Ensembl chr 7:108,569,867...108,574,850
JBrowse link
G DPT dermatopontin multiple interactions EXP [Toluene co-treated with ethylbenzene co-treated with Xylenes] results in decreased methylation of DPT gene; [Toluene co-treated with ethylbenzene co-treated with Xylenes] results in increased expression of DPT mRNA CTD PMID:26018793 NCBI chr 1:168,695,468...168,729,206
Ensembl chr 1:168,695,468...168,729,206
JBrowse link
G EGR3 early growth response 3 increases expression EXP ethylbenzene results in increased expression of EGR3 mRNA CTD PMID:20359517 NCBI chr 8:22,687,659...22,693,480
Ensembl chr 8:22,687,659...22,693,480
JBrowse link
G ELOVL6 ELOVL fatty acid elongase 6 increases expression EXP ethylbenzene results in increased expression of ELOVL6 mRNA CTD PMID:20359517 NCBI chr 4:110,045,846...110,199,199
Ensembl chr 4:110,045,846...110,199,199
JBrowse link
G ENTPD1 ectonucleoside triphosphate diphosphohydrolase 1 multiple interactions EXP [Toluene co-treated with ethylbenzene co-treated with Xylenes] results in decreased methylation of ENTPD1 gene; [Toluene co-treated with ethylbenzene co-treated with Xylenes] results in increased expression of ENTPD1 mRNA CTD PMID:26018793 NCBI chr10:95,710,901...95,877,266
Ensembl chr10:95,711,779...95,877,266
JBrowse link
G EVI2A ecotropic viral integration site 2A increases expression EXP ethylbenzene results in increased expression of EVI2A mRNA CTD PMID:20359517 NCBI chr17:31,316,410...31,321,622
Ensembl chr17:31,316,410...31,321,749
JBrowse link
G FCGR1A Fc fragment of IgG receptor Ia increases expression ISO ethylbenzene results in increased expression of FCGR1 mRNA CTD PMID:20955722 NCBI chr 1:149,782,694...149,800,609
Ensembl chr 1:149,782,671...149,791,675
JBrowse link
G FEZ2 fasciculation and elongation protein zeta 2 multiple interactions EXP [Toluene co-treated with ethylbenzene co-treated with Xylenes] results in decreased expression of FEZ2 mRNA; [Toluene co-treated with ethylbenzene co-treated with Xylenes] results in increased methylation of FEZ2 gene CTD PMID:26018793 NCBI chr 2:36,552,239...36,598,190
Ensembl chr 2:36,531,805...36,646,087
JBrowse link
G FILIP1L filamin A interacting protein 1 like increases expression EXP ethylbenzene results in increased expression of FILIP1L mRNA CTD PMID:20359517 NCBI chr 3:99,828,811...100,114,501
Ensembl chr 3:99,828,811...100,114,513
JBrowse link
G FLVCR1 FLVCR heme transporter 1 multiple interactions EXP [Toluene co-treated with ethylbenzene co-treated with Xylenes] results in decreased expression of FLVCR1 mRNA; [Toluene co-treated with ethylbenzene co-treated with Xylenes] results in increased methylation of FLVCR1 gene CTD PMID:26018793 NCBI chr 1:212,858,275...212,899,363
Ensembl chr 1:212,858,275...212,899,363
JBrowse link
G GADD45A growth arrest and DNA damage inducible alpha increases expression EXP ethylbenzene results in increased expression of GADD45A mRNA CTD PMID:20359517 NCBI chr 1:67,685,201...67,688,334
Ensembl chr 1:67,685,201...67,688,334
JBrowse link
G GH1 growth hormone 1 multiple interactions ISO GH1 protein inhibits the reaction [ethylbenzene results in increased expression of CYP2E1 protein] CTD PMID:11884239 NCBI chr17:63,917,203...63,918,839
Ensembl chr17:63,917,200...63,918,839
JBrowse link
G GP1BB glycoprotein Ib platelet subunit beta decreases expression ISO ethylbenzene results in decreased expression of GP1BB mRNA CTD PMID:20955722 NCBI chr22:19,723,539...19,724,771
Ensembl chr22:19,723,539...19,724,771
JBrowse link
G GSTP1 glutathione S-transferase pi 1 decreases activity EXP ethylbenzene results in decreased activity of GSTP1 protein CTD PMID:18409811 NCBI chr11:67,583,812...67,586,653
Ensembl chr11:67,583,742...67,586,656
JBrowse link
G H3C15 H3 clustered histone 15 multiple interactions EXP [Toluene co-treated with ethylbenzene co-treated with Xylenes] results in decreased expression of H3C15 mRNA; [Toluene co-treated with ethylbenzene co-treated with Xylenes] results in increased methylation of H3C15 gene CTD PMID:26018793 NCBI chr 1:149,852,608...149,853,125
Ensembl chr 1:149,852,619...149,854,274
JBrowse link
G HERC1 HECT and RLD domain containing E3 ubiquitin protein ligase family member 1 decreases expression ISO ethylbenzene results in decreased expression of HERC1 mRNA CTD PMID:20955722 NCBI chr15:63,608,618...63,833,948
Ensembl chr15:63,608,618...63,833,948
JBrowse link
G HERC5 HECT and RLD domain containing E3 ubiquitin protein ligase 5 increases expression EXP ethylbenzene results in increased expression of HERC5 mRNA CTD PMID:20359517 NCBI chr 4:88,456,604...88,506,170
Ensembl chr 4:88,457,119...88,506,163
JBrowse link
G HIVEP2 HIVEP zinc finger 2 increases expression EXP ethylbenzene results in increased expression of HIVEP2 mRNA CTD PMID:20359517 NCBI chr 6:142,751,469...142,945,756
Ensembl chr 6:142,751,469...142,956,698
JBrowse link
G HLA-DMB major histocompatibility complex, class II, DM beta increases expression ISO ethylbenzene results in increased expression of HLA-DMB mRNA CTD PMID:20955722 NCBI chr 6:32,934,636...32,941,028
Ensembl chr 6:32,934,629...32,941,028
JBrowse link
G HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1 increases expression ISO ethylbenzene results in increased expression of RT1-BA mRNA CTD PMID:20955722 NCBI chr 6:32,637,406...32,654,846
Ensembl chr 6:32,628,179...32,647,062
JBrowse link
G HLA-DRB1 major histocompatibility complex, class II, DR beta 1 increases expression ISO ethylbenzene results in increased expression of RT1-DB1 mRNA CTD PMID:20955722 NCBI chr 6:32,578,775...32,589,848
Ensembl chr 6:32,578,769...32,589,848
JBrowse link
G HMOX1 heme oxygenase 1 increases expression EXP
ISO
ethylbenzene results in increased expression of HMOX1 mRNA
ethylbenzene results in increased expression of HMOX1 mRNA; ethylbenzene results in increased expression of HMOX1 protein
CTD PMID:20359517 PMID:24053957 NCBI chr22:35,381,096...35,394,207
Ensembl chr22:35,380,361...35,394,214
JBrowse link
G HNRNPLL heterogeneous nuclear ribonucleoprotein L like increases expression EXP ethylbenzene results in increased expression of HNRNPLL mRNA CTD PMID:20359517 NCBI chr 2:38,561,969...38,603,035
Ensembl chr 2:38,561,969...38,603,586
JBrowse link
G HSPA5 heat shock protein family A (Hsp70) member 5 increases expression EXP ethylbenzene results in increased expression of HSPA5 protein CTD PMID:12183065 NCBI chr 9:125,234,853...125,241,343
Ensembl chr 9:125,234,853...125,241,382
JBrowse link
G IFIT1 interferon induced protein with tetratricopeptide repeats 1 increases expression EXP ethylbenzene results in increased expression of IFIT1 mRNA CTD PMID:20359517 NCBI chr10:89,392,623...89,406,487
Ensembl chr10:89,392,546...89,406,487
JBrowse link
G IFIT2 interferon induced protein with tetratricopeptide repeats 2 increases expression EXP ethylbenzene results in increased expression of IFIT2 mRNA CTD PMID:20359517 NCBI chr10:89,302,046...89,309,271
Ensembl chr10:89,283,694...89,309,271
JBrowse link
G IFIT3 interferon induced protein with tetratricopeptide repeats 3 increases expression EXP ethylbenzene results in increased expression of IFIT3 mRNA CTD PMID:20359517 NCBI chr10:89,327,997...89,340,968
Ensembl chr10:89,327,307...89,377,473
JBrowse link
G IFNGR2 interferon gamma receptor 2 increases expression EXP ethylbenzene results in increased expression of IFNGR2 mRNA CTD PMID:20359517 NCBI chr21:33,402,882...33,437,516
Ensembl chr21:33,403,413...33,479,348
JBrowse link
G IL2RG interleukin 2 receptor subunit gamma increases expression ISO ethylbenzene results in increased expression of IL2RG mRNA CTD PMID:20955722 NCBI chr  X:71,107,404...71,111,577
Ensembl chr  X:71,107,404...71,112,108
JBrowse link
G IL7R interleukin 7 receptor decreases expression ISO ethylbenzene results in decreased expression of IL7R mRNA CTD PMID:20955722 NCBI chr 5:35,856,891...35,879,603
Ensembl chr 5:35,852,695...35,879,603
JBrowse link
G IL9 interleukin 9 increases expression ISO ethylbenzene results in increased expression of IL9 mRNA CTD PMID:20955722 NCBI chr 5:135,892,246...135,895,841
Ensembl chr 5:135,892,246...135,895,841
JBrowse link
G KLF4 Kruppel like factor 4 multiple interactions EXP [Toluene co-treated with ethylbenzene co-treated with Xylenes] results in decreased expression of KLF4 mRNA; [Toluene co-treated with ethylbenzene co-treated with Xylenes] results in increased methylation of KLF4 gene CTD PMID:26018793 NCBI chr 9:107,484,852...107,489,769
Ensembl chr 9:107,484,852...107,490,482
JBrowse link
G MAP3K8 mitogen-activated protein kinase kinase kinase 8 increases expression EXP ethylbenzene results in increased expression of MAP3K8 mRNA CTD PMID:20359517 NCBI chr10:30,434,021...30,461,833
Ensembl chr10:30,434,021...30,461,833
JBrowse link
G MXD1 MAX dimerization protein 1 increases expression EXP ethylbenzene results in increased expression of MXD1 mRNA CTD PMID:20359517 NCBI chr 2:69,915,109...69,942,945
Ensembl chr 2:69,897,688...69,942,945
JBrowse link
G NAMPT nicotinamide phosphoribosyltransferase multiple interactions EXP [Toluene co-treated with ethylbenzene co-treated with Xylenes] results in decreased expression of NAMPT mRNA; [Toluene co-treated with ethylbenzene co-treated with Xylenes] results in increased methylation of NAMPT gene CTD PMID:26018793 NCBI chr 7:106,248,298...106,284,983
Ensembl chr 7:106,248,298...106,285,966
JBrowse link
G NCAM1 neural cell adhesion molecule 1 decreases expression ISO ethylbenzene results in decreased expression of NCAM1 mRNA CTD PMID:20955722 NCBI chr11:112,961,420...113,278,436
Ensembl chr11:112,961,247...113,278,436
JBrowse link
G NCF2 neutrophil cytosolic factor 2 increases expression EXP ethylbenzene results in increased expression of NCF2 mRNA CTD PMID:20359517 NCBI chr 1:183,555,562...183,590,914
Ensembl chr 1:183,555,562...183,590,876
JBrowse link
G NECTIN3 nectin cell adhesion molecule 3 decreases expression ISO ethylbenzene results in decreased expression of NECTIN3 mRNA CTD PMID:20955722 NCBI chr 3:111,071,764...111,201,444
Ensembl chr 3:111,070,071...111,275,563
JBrowse link
G NEDD9 neural precursor cell expressed, developmentally down-regulated 9 increases expression EXP ethylbenzene results in increased expression of NEDD9 mRNA CTD PMID:20359517 NCBI chr 6:11,183,298...11,382,348
Ensembl chr 6:11,183,298...11,382,348
JBrowse link
G NFAT5 nuclear factor of activated T cells 5 increases expression EXP ethylbenzene results in increased expression of NFAT5 mRNA CTD PMID:20359517 NCBI chr16:69,565,952...69,704,654
Ensembl chr16:69,565,094...69,704,666
JBrowse link
G NFATC3 nuclear factor of activated T cells 3 decreases expression ISO ethylbenzene results in decreased expression of NFATC3 mRNA CTD PMID:20955722 NCBI chr16:68,085,370...68,229,259
Ensembl chr16:68,084,751...68,229,259
JBrowse link
G NFIB nuclear factor I B increases expression EXP ethylbenzene results in increased expression of NFIB mRNA CTD PMID:20359517 NCBI chr 9:14,081,843...14,532,077
Ensembl chr 9:14,081,843...14,398,983
JBrowse link
G NFKBIA NFKB inhibitor alpha increases expression EXP ethylbenzene results in increased expression of NFKBIA mRNA CTD PMID:20359517 NCBI chr14:35,401,513...35,404,749
Ensembl chr14:35,401,513...35,404,749
JBrowse link
G OTX1 orthodenticle homeobox 1 multiple interactions EXP [Toluene co-treated with ethylbenzene co-treated with Xylenes] results in decreased expression of OTX1 mRNA; [Toluene co-treated with ethylbenzene co-treated with Xylenes] results in increased methylation of OTX1 gene CTD PMID:26018793 NCBI chr 2:63,049,735...63,057,831
Ensembl chr 2:63,050,057...63,057,836
JBrowse link
G PAPLN papilin, proteoglycan like sulfated glycoprotein multiple interactions EXP [Toluene co-treated with ethylbenzene co-treated with Xylenes] results in decreased expression of PAPLN mRNA; [Toluene co-treated with ethylbenzene co-treated with Xylenes] results in increased methylation of PAPLN gene CTD PMID:26018793 NCBI chr14:73,235,841...73,274,623
Ensembl chr14:73,237,497...73,274,640
JBrowse link
G PDK4 pyruvate dehydrogenase kinase 4 increases expression ISO ethylbenzene results in increased expression of PDK4 mRNA CTD PMID:21182459 NCBI chr 7:95,583,499...95,596,516
Ensembl chr 7:95,583,499...95,596,516
JBrowse link
G PELI1 pellino E3 ubiquitin protein ligase 1 increases expression EXP ethylbenzene results in increased expression of PELI1 mRNA CTD PMID:20359517 NCBI chr 2:64,092,652...64,144,421
Ensembl chr 2:64,092,652...64,144,420
JBrowse link
G PF4 platelet factor 4 decreases expression ISO ethylbenzene results in decreased expression of PF4 mRNA CTD PMID:20955722 NCBI chr 4:73,980,811...73,982,124
Ensembl chr 4:73,980,811...73,982,027
JBrowse link
G PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1 increases expression EXP ethylbenzene results in increased expression of PMAIP1 mRNA CTD PMID:20359517 NCBI chr18:59,899,996...59,904,305
Ensembl chr18:59,899,996...59,904,305
JBrowse link
G PRNP prion protein increases expression EXP ethylbenzene results in increased expression of PRNP mRNA CTD PMID:20359517 NCBI chr20:4,686,456...4,701,588
Ensembl chr20:4,686,350...4,701,590
JBrowse link
G PTGER2 prostaglandin E receptor 2 increases expression EXP ethylbenzene results in increased expression of PTGER2 mRNA CTD PMID:20359517 NCBI chr14:52,314,312...52,328,598
Ensembl chr14:52,314,305...52,328,598
JBrowse link
G PTGS2 prostaglandin-endoperoxide synthase 2 multiple interactions ISO [S-8 fuel co-treated with Benzene co-treated with Toluene co-treated with ethylbenzene co-treated with Xylenes co-treated with pseudocumene co-treated with Naphthalenes co-treated with phenylcyclohexane] results in increased expression of PTGS2 mRNA CTD PMID:17890764 NCBI chr 1:186,671,791...186,680,423
Ensembl chr 1:186,671,791...186,680,922
JBrowse link
G RAB11FIP1 RAB11 family interacting protein 1 multiple interactions EXP [Toluene co-treated with ethylbenzene co-treated with Xylenes] results in decreased expression of RAB11FIP1 mRNA; [Toluene co-treated with ethylbenzene co-treated with Xylenes] results in increased methylation of RAB11FIP1 gene CTD PMID:26018793 NCBI chr 8:37,858,618...37,899,497
Ensembl chr 8:37,858,618...37,899,497
JBrowse link
G RAB8B RAB8B, member RAS oncogene family increases expression EXP ethylbenzene results in increased expression of RAB8B mRNA CTD PMID:20359517 NCBI chr15:63,189,536...63,267,776
Ensembl chr15:63,189,560...63,267,776
JBrowse link
G RELB RELB proto-oncogene, NF-kB subunit increases expression EXP ethylbenzene results in increased expression of RELB mRNA CTD PMID:20359517 NCBI chr19:45,001,449...45,038,194
Ensembl chr19:45,001,449...45,038,198
JBrowse link
G RNF149 ring finger protein 149 increases expression EXP ethylbenzene results in increased expression of RNF149 mRNA CTD PMID:20359517 NCBI chr 2:101,271,213...101,308,701
Ensembl chr 2:101,271,219...101,308,701
JBrowse link
G RP9P RP9 pseudogene multiple interactions EXP [Toluene co-treated with ethylbenzene co-treated with Xylenes] results in decreased expression of RP9P mRNA; [Toluene co-treated with ethylbenzene co-treated with Xylenes] results in increased methylation of RP9P gene CTD PMID:26018793 NCBI chr 7:32,916,815...32,943,170
Ensembl chr 7:32,916,815...32,943,176
JBrowse link
G SELL selectin L increases expression ISO ethylbenzene results in increased expression of SELL mRNA CTD PMID:20955722 NCBI chr 1:169,690,667...169,711,620
Ensembl chr 1:169,690,665...169,711,702
JBrowse link
G SESN2 sestrin 2 increases expression EXP ethylbenzene results in increased expression of SESN2 mRNA CTD PMID:20359517 NCBI chr 1:28,259,452...28,282,491
Ensembl chr 1:28,259,518...28,282,491
JBrowse link
G SLC38A2 solute carrier family 38 member 2 increases expression EXP ethylbenzene results in increased expression of SLC38A2 mRNA CTD PMID:20359517 NCBI chr12:46,358,188...46,372,774
Ensembl chr12:46,358,188...46,372,773
JBrowse link
G SLC7A11 solute carrier family 7 member 11 increases expression EXP ethylbenzene results in increased expression of SLC7A11 mRNA CTD PMID:20359517 NCBI chr 4:138,164,097...138,242,349
Ensembl chr 4:138,164,097...138,242,349
JBrowse link
G STX11 syntaxin 11 increases expression EXP ethylbenzene results in increased expression of STX11 mRNA CTD PMID:20359517 NCBI chr 6:144,140,044...144,191,939
Ensembl chr 6:144,150,517...144,191,939
JBrowse link
G TNFAIP3 TNF alpha induced protein 3 increases expression EXP ethylbenzene results in increased expression of TNFAIP3 mRNA CTD PMID:20359517 NCBI chr 6:137,866,317...137,883,312
Ensembl chr 6:137,867,214...137,883,312
JBrowse link
G TOP2A DNA topoisomerase II alpha increases methylation EXP ethylbenzene results in increased methylation of TOP2A promoter CTD PMID:29217486 NCBI chr17:40,388,525...40,417,902
Ensembl chr17:40,388,525...40,417,896
JBrowse link
G TRIP12 thyroid hormone receptor interactor 12 decreases expression ISO ethylbenzene results in decreased expression of TRIP12 mRNA CTD PMID:20955722 NCBI chr 2:229,763,837...229,923,234
Ensembl chr 2:229,763,837...229,923,239
JBrowse link
G USP18 ubiquitin specific peptidase 18 increases expression EXP ethylbenzene results in increased expression of USP18 mRNA CTD PMID:20359517 NCBI chr22:18,149,855...18,177,397
Ensembl chr22:18,150,170...18,177,397
JBrowse link
G WASHC2C WASH complex subunit 2C multiple interactions EXP [Toluene co-treated with ethylbenzene co-treated with Xylenes] results in decreased expression of WASHC2C mRNA; [Toluene co-treated with ethylbenzene co-treated with Xylenes] results in increased methylation of WASHC2C gene CTD PMID:26018793 NCBI chr10:45,727,043...45,792,964
Ensembl chr10:45,727,200...45,792,964
JBrowse link
G WWP1 WW domain containing E3 ubiquitin protein ligase 1 decreases expression ISO ethylbenzene results in decreased expression of WWP1 mRNA CTD PMID:20955722 NCBI chr 8:86,342,547...86,468,503
Ensembl chr 8:86,342,547...86,478,420
JBrowse link
G XBP1 X-box binding protein 1 increases expression EXP ethylbenzene results in increased expression of XBP1 mRNA CTD PMID:20359517 NCBI chr22:28,794,560...28,800,569
Ensembl chr22:28,794,555...28,800,597
JBrowse link
G ZC3HAV1 zinc finger CCCH-type containing, antiviral 1 increases expression EXP ethylbenzene results in increased expression of ZC3HAV1 mRNA CTD PMID:20359517 NCBI chr 7:139,043,515...139,109,720
Ensembl chr 7:139,043,515...139,132,122
JBrowse link
G ZCCHC2 zinc finger CCHC-type containing 2 increases expression EXP ethylbenzene results in increased expression of ZCCHC2 mRNA CTD PMID:20359517 NCBI chr18:62,523,025...62,587,709
Ensembl chr18:62,523,025...62,587,709
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 24775
    role 24693
      chemical role 22996
        environmental contaminant 20077
          benzene 6001
            alkylbenzene 3497
              ethylbenzene 104
Path 2
Term Annotations click to browse term
  CHEBI ontology 24775
    subatomic particle 24735
      composite particle 24735
        hadron 24735
          baryon 24735
            nucleon 24735
              atomic nucleus 24735
                atom 24735
                  main group element atom 24601
                    main group molecular entity 24601
                      s-block molecular entity 23907
                        hydrogen molecular entity 23745
                          hydrides 21962
                            organic hydride 21455
                              organic fundamental parent 21455
                                hydrocarbon 21134
                                  cyclic hydrocarbon 19952
                                    monocyclic hydrocarbon 6172
                                      annulene 6001
                                        aromatic annulene 6001
                                          benzene 6001
                                            alkylbenzene 3497
                                              ethylbenzene 104
paths to the root