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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:ethylbenzene
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Accession:CHEBI:16101 term browser browse the term
Definition:An alkylbenzene carrying an ethyl substituent. It is a constituent of coal tar and petroleum.
Synonyms:related_synonym: Aethylbenzol;   Ethylbenzol;   Ethylenzene;   Formula=C8H10;   InChI=1S/C8H10/c1-2-8-6-4-3-5-7-8/h3-7H,2H2,1H3;   InChIKey=YNQLUTRBYVCPMQ-UHFFFAOYSA-N;   Phenylethane;   SMILES=CCc1ccccc1;   alpha-methyltoluene
 alt_id: CHEBI:14229;   CHEBI:23999;   CHEBI:45136;   CHEBI:4898
 xref: Beilstein:1901871;   CAS:100-41-4;   DrugBank:DB01722;   Gmelin:2990;   HMDB:HMDB0059905;   KEGG:C07111
 xref_mesh: MESH:C004912
 xref: MetaCyc:ETHYLBENZENE;   Reaxys:1901871;   UM-BBD_compID:c0116;   Wikipedia:Ethylbenzene


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ethylbenzene term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ace angiotensin I converting enzyme multiple interactions ISO [Toluene co-treated with ethylbenzene co-treated with Xylenes] results in decreased methylation of ACE gene; [Toluene co-treated with ethylbenzene co-treated with Xylenes] results in increased expression of ACE mRNA CTD PMID:26018793 NCBI chr10:94,170,766...94,213,831
Ensembl chr10:94,170,766...94,187,822
JBrowse link
G Ache acetylcholinesterase decreases expression EXP ethylbenzene results in decreased expression of ACHE protein CTD PMID:21241565 NCBI chr12:22,472,358...22,477,052
Ensembl chr12:22,472,358...22,478,753
JBrowse link
G Bax BCL2 associated X, apoptosis regulator decreases expression
increases expression
EXP ethylbenzene results in decreased expression of BAX protein
ethylbenzene results in increased expression of BAX mRNA; ethylbenzene results in increased expression of BAX protein
CTD PMID:20137408 PMID:20156836 PMID:21241565 PMID:25518993 NCBI chr 1:101,451,801...101,457,207
Ensembl chr 1:101,451,802...101,457,207
JBrowse link
G Bcl2 BCL2, apoptosis regulator decreases expression EXP ethylbenzene results in decreased expression of BCL2 mRNA; ethylbenzene results in decreased expression of BCL2 protein CTD PMID:20137408 PMID:20156836 PMID:21241565 PMID:25518993 NCBI chr13:26,605,426...26,769,374
Ensembl chr13:26,605,426...26,769,374
JBrowse link
G Bcl2a1 BCL2-related protein A1 increases expression ISO ethylbenzene results in increased expression of BCL2A1 mRNA CTD PMID:20359517 NCBI chr 8:96,551,424...96,559,527
Ensembl chr 8:96,551,245...96,559,483
JBrowse link
G Bcl6 BCL6, transcription repressor increases expression ISO ethylbenzene results in increased expression of BCL6 mRNA CTD PMID:20359517 NCBI chr11:80,255,790...80,279,075
Ensembl chr11:80,255,790...80,279,075
JBrowse link
G Birc3 baculoviral IAP repeat-containing 3 increases expression ISO ethylbenzene results in increased expression of BIRC3 mRNA CTD PMID:20359517 NCBI chr 8:6,048,590...6,076,828
Ensembl chr 8:6,048,969...6,076,598
JBrowse link
G Btg1 BTG anti-proliferation factor 1 increases expression ISO ethylbenzene results in increased expression of BTG1 mRNA CTD PMID:20359517 NCBI chr 7:37,812,831...37,815,088
Ensembl chr 7:37,812,831...37,815,088
JBrowse link
G Carmil3 capping protein regulator and myosin 1 linker 3 multiple interactions ISO [Toluene co-treated with ethylbenzene co-treated with Xylenes] results in decreased methylation of CARMIL3 gene; [Toluene co-treated with ethylbenzene co-treated with Xylenes] results in increased expression of CARMIL3 mRNA CTD PMID:26018793 NCBI chr15:34,167,146...34,184,799
Ensembl chr15:34,167,945...34,184,799
JBrowse link
G Casp3 caspase 3 increases expression EXP ethylbenzene results in increased expression of CASP3 mRNA; ethylbenzene results in increased expression of CASP3 protein CTD PMID:20137408 PMID:20156836 PMID:21241565 PMID:25518993 NCBI chr16:48,845,011...48,863,249
Ensembl chr16:48,845,012...48,863,204
JBrowse link
G Casp9 caspase 9 increases expression EXP ethylbenzene results in increased expression of CASP9 mRNA; ethylbenzene results in increased expression of CASP9 protein CTD PMID:20137408 PMID:20156836 PMID:21241565 PMID:25518993 NCBI chr 5:160,356,211...160,373,774
Ensembl chr 5:160,355,833...160,373,778
JBrowse link
G Cat catalase decreases activity EXP ethylbenzene results in decreased activity of CAT protein CTD PMID:24053957 NCBI chr 3:93,379,872...93,412,058
Ensembl chr 3:93,379,874...93,412,058
JBrowse link
G Cblb Cbl proto-oncogene B increases expression EXP ethylbenzene results in increased expression of CBLB mRNA CTD PMID:20955722 NCBI chr11:51,037,383...51,202,761
Ensembl chr11:51,037,393...51,202,820
JBrowse link
G Ccl5 C-C motif chemokine ligand 5 decreases expression EXP ethylbenzene results in decreased expression of CCL5 mRNA CTD PMID:20955722 NCBI chr10:70,739,764...70,744,303
Ensembl chr10:70,739,800...70,744,315
JBrowse link
G Cd37 CD37 molecule decreases expression EXP ethylbenzene results in decreased expression of CD37 mRNA CTD PMID:20955722 NCBI chr 1:101,230,470...101,236,061
Ensembl chr 1:101,230,533...101,236,065
JBrowse link
G Cd38 CD38 molecule increases expression EXP ethylbenzene results in increased expression of CD38 mRNA CTD PMID:20955722 NCBI chr14:71,714,768...71,754,990
Ensembl chr14:71,715,269...71,754,672
JBrowse link
G Cd4 Cd4 molecule increases expression EXP ethylbenzene results in increased expression of CD4 mRNA CTD PMID:20955722 NCBI chr 4:157,381,862...157,408,357
Ensembl chr 4:157,383,052...157,408,176
JBrowse link
G Cd8a CD8a molecule increases expression EXP ethylbenzene results in increased expression of CD8A mRNA CTD PMID:20955722 NCBI chr 4:99,217,640...99,243,352
Ensembl chr 4:99,239,115...99,243,351
JBrowse link
G Cdcp2 CUB domain containing protein 2 multiple interactions ISO [Toluene co-treated with ethylbenzene co-treated with Xylenes] results in decreased methylation of CDCP2 gene; [Toluene co-treated with ethylbenzene co-treated with Xylenes] results in increased expression of CDCP2 mRNA CTD PMID:26018793 NCBI chr 5:126,697,728...126,716,150
Ensembl chr 5:126,698,582...126,708,762
JBrowse link
G Chrna10 cholinergic receptor nicotinic alpha 10 subunit multiple interactions ISO ethylbenzene inhibits the reaction [Acetylcholine results in increased activity of [CHRNA9 protein binds to CHRNA10 protein]] CTD PMID:18602458 NCBI chr 1:167,206,722...167,212,199
Ensembl chr 1:167,206,722...167,210,919
JBrowse link
G Chrna9 cholinergic receptor nicotinic alpha 9 subunit multiple interactions ISO ethylbenzene inhibits the reaction [Acetylcholine results in increased activity of [CHRNA9 protein binds to CHRNA10 protein]] CTD PMID:18602458 NCBI chr14:43,883,450...43,890,171
Ensembl chr14:43,883,458...43,890,171
JBrowse link
G Ciita class II, major histocompatibility complex, transactivator increases expression EXP ethylbenzene results in increased expression of CIITA mRNA CTD PMID:20955722 NCBI chr10:5,212,621...5,260,641
Ensembl chr10:5,213,350...5,260,608
JBrowse link
G Clcn4 chloride voltage-gated channel 4 multiple interactions ISO [Toluene co-treated with ethylbenzene co-treated with Xylenes] results in decreased expression of CLCN4 mRNA; [Toluene co-treated with ethylbenzene co-treated with Xylenes] results in increased methylation of CLCN4 gene CTD PMID:26018793 NCBI chr  X:25,016,177...25,082,563
Ensembl chr  X:25,016,401...25,080,410
JBrowse link
G Cth cystathionine gamma-lyase increases expression ISO ethylbenzene results in increased expression of CTH mRNA CTD PMID:20359517 NCBI chr 2:264,266,959...264,293,040
Ensembl chr 2:264,266,984...264,293,046
JBrowse link
G Cxcr2 C-X-C motif chemokine receptor 2 increases expression EXP ethylbenzene results in increased expression of CXCR2 mRNA CTD PMID:20955722 NCBI chr 9:81,427,275...81,435,065
Ensembl chr 9:81,427,730...81,434,102
JBrowse link
G Cxcr4 C-X-C motif chemokine receptor 4 increases expression ISO ethylbenzene results in increased expression of CXCR4 mRNA CTD PMID:20359517 NCBI chr13:45,314,952...45,318,856
Ensembl chr13:45,314,933...45,318,878
JBrowse link
G Cycs cytochrome c, somatic increases expression EXP ethylbenzene results in increased expression of CYCS mRNA; ethylbenzene results in increased expression of CYCS protein CTD PMID:20137408 PMID:20156836 PMID:21241565 PMID:25518993 NCBI chr 4:80,331,226...80,333,326
Ensembl chr 4:80,331,227...80,333,326
JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 increases expression
multiple interactions
EXP
ISO
ethylbenzene results in increased expression of CYP1A1 protein
CYP1A1 gene polymorphism affects the susceptibility to [Benzene co-treated with Toluene co-treated with ethylbenzene co-treated with Xylenes]
CTD PMID:8135039 PMID:23138419 NCBI chr 8:62,472,087...62,478,122
Ensembl chr 8:62,472,095...62,478,147
JBrowse link
G Cyp1b1 cytochrome P450, family 1, subfamily b, polypeptide 1 decreases expression ISO ethylbenzene results in decreased expression of CYP1B1 mRNA CTD PMID:20359517 NCBI chr 6:2,308,179...2,316,739
Ensembl chr 6:2,307,808...2,316,722
JBrowse link
G Cyp2b1 cytochrome P450, family 2, subfamily b, polypeptide 1 increases expression EXP ethylbenzene results in increased expression of CYP2B1 protein CTD PMID:1417939 PMID:8135039 NCBI chr 7:99,142,431...99,183,540
Ensembl chr 7:99,142,450...99,181,783
JBrowse link
G Cyp2b2 cytochrome P450, family 2, subfamily b, polypeptide 2 increases expression EXP ethylbenzene results in increased expression of CYP2B2 protein CTD PMID:1417939 PMID:8135039 NCBI chr 1:83,103,925...83,119,578
Ensembl chr 1:83,103,925...83,119,193
JBrowse link
G Cyp2c11 cytochrome P450, subfamily 2, polypeptide 11 decreases expression EXP ethylbenzene results in decreased expression of CYP2C11 protein CTD PMID:8135039 NCBI chr 1:257,676,172...258,004,428
Ensembl chr 1:257,970,345...258,004,434
JBrowse link
G Cyp2e1 cytochrome P450, family 2, subfamily e, polypeptide 1 multiple interactions
increases expression
EXP ethylbenzene results in increased expression of and results in increased activity of CYP2E1 protein; GH1 protein inhibits the reaction [ethylbenzene results in increased expression of CYP2E1 protein]
ethylbenzene results in increased expression of CYP2E1 mRNA; ethylbenzene results in increased expression of CYP2E1 protein
CTD PMID:1417939 PMID:8517779 PMID:11884239 NCBI chr 1:213,511,892...213,522,195
Ensembl chr 1:213,511,874...213,535,542
JBrowse link
G Dennd5a DENN domain containing 5A increases expression ISO ethylbenzene results in increased expression of DENND5A mRNA CTD PMID:20359517 NCBI chr 1:174,524,047...174,588,553
Ensembl chr 1:174,524,047...174,588,529
JBrowse link
G Dnajb9 DnaJ heat shock protein family (Hsp40) member B9 increases expression ISO ethylbenzene results in increased expression of DNAJB9 mRNA CTD PMID:20359517 NCBI chr 6:64,165,913...64,170,122
Ensembl chr 6:64,165,913...64,170,151
JBrowse link
G Dpt dermatopontin multiple interactions ISO [Toluene co-treated with ethylbenzene co-treated with Xylenes] results in decreased methylation of DPT gene; [Toluene co-treated with ethylbenzene co-treated with Xylenes] results in increased expression of DPT mRNA CTD PMID:26018793 NCBI chr13:83,073,307...83,102,404
Ensembl chr13:83,073,544...83,102,401
JBrowse link
G Egr3 early growth response 3 increases expression ISO ethylbenzene results in increased expression of EGR3 mRNA CTD PMID:20359517 NCBI chr15:51,756,683...51,762,080
Ensembl chr15:51,756,736...51,760,722
JBrowse link
G Elovl6 ELOVL fatty acid elongase 6 increases expression ISO ethylbenzene results in increased expression of ELOVL6 mRNA CTD PMID:20359517 NCBI chr 2:234,187,490...234,296,124
Ensembl chr 2:234,189,105...234,296,145
Ensembl chr 2:234,189,105...234,296,145
JBrowse link
G Entpd1 ectonucleoside triphosphate diphosphohydrolase 1 multiple interactions ISO [Toluene co-treated with ethylbenzene co-treated with Xylenes] results in decreased methylation of ENTPD1 gene; [Toluene co-treated with ethylbenzene co-treated with Xylenes] results in increased expression of ENTPD1 mRNA CTD PMID:26018793 NCBI chr 1:259,692,020...259,818,922
Ensembl chr 1:259,739,955...259,819,494
JBrowse link
G Evi2a ecotropic viral integration site 2A increases expression ISO ethylbenzene results in increased expression of EVI2A mRNA CTD PMID:20359517 NCBI chr10:66,870,048...66,873,948
Ensembl chr10:66,870,067...66,873,948
JBrowse link
G Fcgr1a Fc fragment of IgG receptor Ia increases expression EXP ethylbenzene results in increased expression of FCGR1 mRNA CTD PMID:20955722 NCBI chr 2:198,430,536...198,439,453
Ensembl chr 2:198,430,530...198,458,041
JBrowse link
G Fez2 fasciculation and elongation protein zeta 2 multiple interactions ISO [Toluene co-treated with ethylbenzene co-treated with Xylenes] results in decreased expression of FEZ2 mRNA; [Toluene co-treated with ethylbenzene co-treated with Xylenes] results in increased methylation of FEZ2 gene CTD PMID:26018793 NCBI chr 6:963,903...1,003,955
Ensembl chr 6:963,907...1,004,001
JBrowse link
G Filip1l filamin A interacting protein 1-like increases expression ISO ethylbenzene results in increased expression of FILIP1L mRNA CTD PMID:20359517 NCBI chr11:45,039,488...45,275,141
Ensembl chr11:45,039,461...45,124,423
JBrowse link
G Flvcr1 FLVCR heme transporter 1 multiple interactions ISO [Toluene co-treated with ethylbenzene co-treated with Xylenes] results in decreased expression of FLVCR1 mRNA; [Toluene co-treated with ethylbenzene co-treated with Xylenes] results in increased methylation of FLVCR1 gene CTD PMID:26018793 NCBI chr13:109,578,294...109,624,235
Ensembl chr13:109,578,074...109,629,482
JBrowse link
G Gadd45a growth arrest and DNA-damage-inducible, alpha increases expression ISO ethylbenzene results in increased expression of GADD45A mRNA CTD PMID:20359517 NCBI chr 4:97,782,512...97,784,814
Ensembl chr 4:97,782,512...97,784,842
JBrowse link
G Gh1 growth hormone 1 multiple interactions EXP GH1 protein inhibits the reaction [ethylbenzene results in increased expression of CYP2E1 protein] CTD PMID:11884239 NCBI chr10:94,486,204...94,488,181
Ensembl chr10:94,486,205...94,488,180
JBrowse link
G Gp1bb glycoprotein Ib platelet subunit beta decreases expression EXP ethylbenzene results in decreased expression of GP1BB mRNA CTD PMID:20955722 NCBI chr11:86,520,992...86,522,169
Ensembl chr11:86,520,992...86,522,169
JBrowse link
G Gstp1 glutathione S-transferase pi 1 decreases activity ISO ethylbenzene results in decreased activity of GSTP1 protein CTD PMID:18409811 NCBI chr 1:219,291,679...219,294,147
Ensembl chr 1:219,291,679...219,294,147
JBrowse link
G Herc1 HECT and RLD domain containing E3 ubiquitin protein ligase family member 1 decreases expression EXP ethylbenzene results in decreased expression of HERC1 mRNA CTD PMID:20955722 NCBI chr 8:72,029,550...72,198,363
Ensembl chr 8:72,029,489...72,198,358
JBrowse link
G Hivep2 HIVEP zinc finger 2 increases expression ISO ethylbenzene results in increased expression of HIVEP2 mRNA CTD PMID:20359517 NCBI chr 1:8,129,354...8,333,890
Ensembl chr 1:8,310,577...8,333,885
JBrowse link
G Hmox1 heme oxygenase 1 increases expression ISO
EXP
ethylbenzene results in increased expression of HMOX1 mRNA
ethylbenzene results in increased expression of HMOX1 mRNA; ethylbenzene results in increased expression of HMOX1 protein
CTD PMID:20359517 PMID:24053957 NCBI chr19:14,508,634...14,515,455
Ensembl chr19:14,508,616...14,515,456
JBrowse link
G Hnrnpll heterogeneous nuclear ribonucleoprotein L-like increases expression ISO ethylbenzene results in increased expression of HNRNPLL mRNA CTD PMID:20359517 NCBI chr 6:2,698,983...2,729,715
Ensembl chr 6:2,699,961...2,729,394
JBrowse link
G Hspa5 heat shock protein family A (Hsp70) member 5 increases expression ISO ethylbenzene results in increased expression of HSPA5 protein CTD PMID:12183065 NCBI chr 3:13,838,304...13,842,763
Ensembl chr 3:13,838,304...13,842,762
JBrowse link
G Ifit2 interferon-induced protein with tetratricopeptide repeats 2 increases expression ISO ethylbenzene results in increased expression of IFIT2 mRNA CTD PMID:20359517 NCBI chr 1:252,894,663...252,900,727
Ensembl chr 1:252,894,663...252,900,726
JBrowse link
G Ifit3 interferon-induced protein with tetratricopeptide repeats 3 increases expression ISO ethylbenzene results in increased expression of IFIT3 mRNA CTD PMID:20359517 NCBI chr 1:252,906,234...252,911,377
Ensembl chr 1:252,906,234...252,911,382
JBrowse link
G Ifngr2 interferon gamma receptor 2 increases expression ISO ethylbenzene results in increased expression of IFNGR2 mRNA CTD PMID:20359517 NCBI chr11:31,694,339...31,712,611
Ensembl chr11:31,694,339...31,712,611
JBrowse link
G Il2rg interleukin 2 receptor subunit gamma increases expression EXP ethylbenzene results in increased expression of IL2RG mRNA CTD PMID:20955722 NCBI chr  X:71,165,378...71,169,078
Ensembl chr  X:71,162,585...71,169,865
JBrowse link
G Il7r interleukin 7 receptor decreases expression EXP ethylbenzene results in decreased expression of IL7R mRNA CTD PMID:20955722
G Il9 interleukin 9 increases expression EXP ethylbenzene results in increased expression of IL9 mRNA CTD PMID:20955722 NCBI chr17:8,558,827...8,561,950
Ensembl chr17:8,558,827...8,561,950
JBrowse link
G Klf4 Kruppel like factor 4 multiple interactions ISO [Toluene co-treated with ethylbenzene co-treated with Xylenes] results in decreased expression of KLF4 mRNA; [Toluene co-treated with ethylbenzene co-treated with Xylenes] results in increased methylation of KLF4 gene CTD PMID:26018793 NCBI chr 5:72,283,311...72,287,669
Ensembl chr 5:72,283,313...72,287,669
JBrowse link
G LOC690126 hypothetical protein LOC690126 multiple interactions ISO [Toluene co-treated with ethylbenzene co-treated with Xylenes] results in decreased expression of H3C15 mRNA; [Toluene co-treated with ethylbenzene co-treated with Xylenes] results in increased methylation of H3C15 gene CTD PMID:26018793 NCBI chr 2:198,379,864...198,381,026
Ensembl chr 2:198,380,426...198,380,836
JBrowse link
G Map3k8 mitogen-activated protein kinase kinase kinase 8 increases expression ISO ethylbenzene results in increased expression of MAP3K8 mRNA CTD PMID:20359517 NCBI chr17:56,109,403...56,129,925
Ensembl chr17:56,109,549...56,129,919
JBrowse link
G Mxd1 max dimerization protein 1 increases expression ISO ethylbenzene results in increased expression of MXD1 mRNA CTD PMID:20359517 NCBI chr 4:118,451,752...118,472,150
Ensembl chr 4:118,449,882...118,472,179
JBrowse link
G Nampt nicotinamide phosphoribosyltransferase multiple interactions ISO [Toluene co-treated with ethylbenzene co-treated with Xylenes] results in decreased expression of NAMPT mRNA; [Toluene co-treated with ethylbenzene co-treated with Xylenes] results in increased methylation of NAMPT gene CTD PMID:26018793 NCBI chr 6:52,122,085...52,156,473
Ensembl chr 6:52,122,085...52,156,472
JBrowse link
G Ncam1 neural cell adhesion molecule 1 decreases expression EXP ethylbenzene results in decreased expression of NCAM1 mRNA CTD PMID:20955722 NCBI chr 8:53,836,797...54,134,881
Ensembl chr 8:53,839,098...53,901,358
JBrowse link
G Ncf2 neutrophil cytosolic factor 2 increases expression ISO ethylbenzene results in increased expression of NCF2 mRNA CTD PMID:20359517 NCBI chr13:70,226,441...70,259,019
Ensembl chr13:70,226,647...70,257,576
JBrowse link
G Nectin3 nectin cell adhesion molecule 3 decreases expression EXP ethylbenzene results in decreased expression of NECTIN3 mRNA CTD PMID:20955722 NCBI chr11:57,897,879...57,995,193
Ensembl chr11:57,897,879...57,993,548
JBrowse link
G Nedd9 neural precursor cell expressed, developmentally down-regulated 9 increases expression ISO ethylbenzene results in increased expression of NEDD9 mRNA CTD PMID:20359517 NCBI chr17:22,984,792...23,179,701
Ensembl chr17:22,984,844...23,179,701
JBrowse link
G Nfat5 nuclear factor of activated T-cells 5 increases expression ISO ethylbenzene results in increased expression of NFAT5 mRNA CTD PMID:20359517 NCBI chr19:38,446,059...38,533,735
Ensembl chr19:38,446,059...38,533,735
JBrowse link
G Nfatc3 nuclear factor of activated T-cells 3 decreases expression EXP ethylbenzene results in decreased expression of NFATC3 mRNA CTD PMID:20955722 NCBI chr19:38,039,542...38,114,003
Ensembl chr19:38,039,564...38,114,003
JBrowse link
G Nfib nuclear factor I/B increases expression ISO ethylbenzene results in increased expression of NFIB mRNA CTD PMID:20359517 NCBI chr 5:100,436,343...100,647,962
Ensembl chr 5:100,439,082...100,647,727
JBrowse link
G Nfkbia NFKB inhibitor alpha increases expression ISO ethylbenzene results in increased expression of NFKBIA mRNA CTD PMID:20359517 NCBI chr 6:76,267,227...76,270,457
Ensembl chr 6:76,267,228...76,270,457
JBrowse link
G Otx1 orthodenticle homeobox 1 multiple interactions ISO [Toluene co-treated with ethylbenzene co-treated with Xylenes] results in decreased expression of OTX1 mRNA; [Toluene co-treated with ethylbenzene co-treated with Xylenes] results in increased methylation of OTX1 gene CTD PMID:26018793 NCBI chr14:106,861,556...106,864,933
Ensembl chr14:106,861,676...106,864,892
JBrowse link
G Papln papilin, proteoglycan-like sulfated glycoprotein multiple interactions ISO [Toluene co-treated with ethylbenzene co-treated with Xylenes] results in decreased expression of PAPLN mRNA; [Toluene co-treated with ethylbenzene co-treated with Xylenes] results in increased methylation of PAPLN gene CTD PMID:26018793 NCBI chr 6:107,245,573...107,282,256
Ensembl chr 6:107,245,820...107,276,755
JBrowse link
G Pdk4 pyruvate dehydrogenase kinase 4 increases expression ISO ethylbenzene results in increased expression of PDK4 mRNA CTD PMID:21182459 NCBI chr 4:30,546,772...30,556,774
Ensembl chr 4:30,546,664...30,556,814
JBrowse link
G Peli1 pellino E3 ubiquitin protein ligase 1 increases expression ISO ethylbenzene results in increased expression of PELI1 mRNA CTD PMID:20359517 NCBI chr14:106,008,086...106,062,566
Ensembl chr14:106,008,086...106,061,641
JBrowse link
G Pf4 platelet factor 4 decreases expression EXP ethylbenzene results in decreased expression of PF4 mRNA CTD PMID:20955722 NCBI chr14:18,848,549...18,849,258
Ensembl chr14:18,848,549...18,849,258
JBrowse link
G Pmaip1 phorbol-12-myristate-13-acetate-induced protein 1 increases expression ISO ethylbenzene results in increased expression of PMAIP1 mRNA CTD PMID:20359517 NCBI chr18:62,159,128...62,179,635
Ensembl chr18:62,174,670...62,181,102
JBrowse link
G Prnp prion protein increases expression ISO ethylbenzene results in increased expression of PRNP mRNA CTD PMID:20359517 NCBI chr 3:124,515,917...124,531,320
Ensembl chr 3:124,515,978...124,531,316
JBrowse link
G Ptger2 prostaglandin E receptor 2 increases expression ISO ethylbenzene results in increased expression of PTGER2 mRNA CTD PMID:20359517 NCBI chr15:19,336,029...19,349,759
Ensembl chr15:19,338,175...19,350,210
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 multiple interactions ISO [S-8 fuel co-treated with Benzene co-treated with Toluene co-treated with ethylbenzene co-treated with Xylenes co-treated with pseudocumene co-treated with Naphthalenes co-treated with phenylcyclohexane] results in increased expression of PTGS2 mRNA CTD PMID:17890764 NCBI chr13:67,351,230...67,356,920
Ensembl chr13:67,351,087...67,359,335
JBrowse link
G Rab11fip1 RAB11 family interacting protein 1 multiple interactions ISO [Toluene co-treated with ethylbenzene co-treated with Xylenes] results in decreased expression of RAB11FIP1 mRNA; [Toluene co-treated with ethylbenzene co-treated with Xylenes] results in increased methylation of RAB11FIP1 gene CTD PMID:26018793 NCBI chr16:69,048,739...69,079,332
Ensembl chr16:69,046,514...69,079,332
JBrowse link
G Rab8b RAB8B, member RAS oncogene family increases expression ISO ethylbenzene results in increased expression of RAB8B mRNA CTD PMID:20359517 NCBI chr 8:72,641,680...72,714,646
Ensembl chr 8:72,638,003...72,714,664
JBrowse link
G Relb RELB proto-oncogene, NF-kB subunit increases expression ISO ethylbenzene results in increased expression of RELB mRNA CTD PMID:20359517 NCBI chr 1:80,517,081...80,545,019
Ensembl chr 1:80,517,411...80,544,825
JBrowse link
G Rnf149 ring finger protein 149 increases expression ISO ethylbenzene results in increased expression of RNF149 mRNA CTD PMID:20359517 NCBI chr 9:46,285,546...46,309,692
Ensembl chr 9:46,286,657...46,309,451
JBrowse link
G RT1-Ba RT1 class II, locus Ba increases expression EXP ethylbenzene results in increased expression of RT1-BA mRNA CTD PMID:20955722 NCBI chr20:4,066,133...4,070,726
Ensembl chr20:4,066,132...4,070,721
JBrowse link
G RT1-Db1 RT1 class II, locus Db1 increases expression EXP ethylbenzene results in increased expression of RT1-DB1 mRNA CTD PMID:20955722 NCBI chr20:4,087,621...4,097,190
Ensembl chr20:4,087,618...4,097,190
JBrowse link
G RT1-DMb RT1 class II, locus DMb increases expression EXP ethylbenzene results in increased expression of HLA-DMB mRNA CTD PMID:20955722 NCBI chr20:3,945,383...3,952,838
Ensembl chr20:5,227,045...5,234,290
Ensembl chr20:5,227,045...5,234,290
JBrowse link
G Sell selectin L increases expression EXP ethylbenzene results in increased expression of SELL mRNA CTD PMID:20955722 NCBI chr13:82,369,820...82,387,774
Ensembl chr13:82,369,493...82,387,631
JBrowse link
G Sesn2 sestrin 2 increases expression ISO ethylbenzene results in increased expression of SESN2 mRNA CTD PMID:20359517 NCBI chr 5:150,684,891...150,703,846
Ensembl chr 5:150,684,133...150,704,117
JBrowse link
G Slc38a2 solute carrier family 38, member 2 increases expression ISO ethylbenzene results in increased expression of SLC38A2 mRNA CTD PMID:20359517 NCBI chr 7:138,088,654...138,100,869
Ensembl chr 7:138,088,649...138,100,841
JBrowse link
G Slc7a11 solute carrier family 7 member 11 increases expression ISO ethylbenzene results in increased expression of SLC7A11 mRNA CTD PMID:20359517 NCBI chr 2:139,453,774...139,528,479
Ensembl chr 2:139,453,774...139,528,162
JBrowse link
G Stx11 syntaxin 11 increases expression ISO ethylbenzene results in increased expression of STX11 mRNA CTD PMID:20359517 NCBI chr 1:7,039,160...7,064,870
Ensembl chr 1:7,039,162...7,064,870
JBrowse link
G Tnfaip3 TNF alpha induced protein 3 increases expression ISO ethylbenzene results in increased expression of TNFAIP3 mRNA CTD PMID:20359517 NCBI chr 1:14,401,103...14,416,369
Ensembl chr 1:14,402,913...14,412,807
JBrowse link
G Top2a DNA topoisomerase II alpha increases methylation ISO ethylbenzene results in increased methylation of TOP2A promoter CTD PMID:29217486 NCBI chr10:86,901,467...86,930,947
Ensembl chr10:86,901,007...86,932,154
JBrowse link
G Trip12 thyroid hormone receptor interactor 12 decreases expression EXP ethylbenzene results in decreased expression of TRIP12 mRNA CTD PMID:20955722 NCBI chr 9:92,305,059...92,435,388
Ensembl chr 9:92,305,051...92,435,365
JBrowse link
G Usp18 ubiquitin specific peptidase 18 increases expression ISO ethylbenzene results in increased expression of USP18 mRNA CTD PMID:20359517 NCBI chr 4:153,812,312...153,834,374
Ensembl chr 4:153,805,993...153,834,430
JBrowse link
G Washc2c WASH complex subunit 2C multiple interactions ISO [Toluene co-treated with ethylbenzene co-treated with Xylenes] results in decreased expression of WASHC2C mRNA; [Toluene co-treated with ethylbenzene co-treated with Xylenes] results in increased methylation of WASHC2C gene CTD PMID:26018793 NCBI chr 4:148,139,512...148,197,363
Ensembl chr 4:148,139,528...148,197,365
JBrowse link
G Wwp1 WW domain containing E3 ubiquitin protein ligase 1 decreases expression EXP ethylbenzene results in decreased expression of WWP1 mRNA CTD PMID:20955722 NCBI chr 5:33,608,489...33,696,487
Ensembl chr 5:33,609,136...33,664,435
JBrowse link
G Xbp1 X-box binding protein 1 increases expression ISO ethylbenzene results in increased expression of XBP1 mRNA CTD PMID:20359517 NCBI chr14:85,753,736...85,758,820
Ensembl chr14:85,753,760...85,758,145
JBrowse link
G Zc3hav1 zinc finger CCCH-type containing, antiviral 1 increases expression ISO ethylbenzene results in increased expression of ZC3HAV1 mRNA CTD PMID:20359517 NCBI chr 4:66,012,111...66,062,160
Ensembl chr 4:66,011,915...66,062,089
JBrowse link
G Zcchc2 zinc finger CCHC-type containing 2 increases expression ISO ethylbenzene results in increased expression of ZCCHC2 mRNA CTD PMID:20359517 NCBI chr13:25,961,762...26,052,472
Ensembl chr13:25,966,428...26,013,338
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19771
    role 19716
      chemical role 19256
        environmental contaminant 18595
          benzene 5643
            alkylbenzene 3365
              ethylbenzene 102
Path 2
Term Annotations click to browse term
  CHEBI ontology 19771
    subatomic particle 19770
      composite particle 19770
        hadron 19770
          baryon 19770
            nucleon 19770
              atomic nucleus 19770
                atom 19770
                  main group element atom 19658
                    main group molecular entity 19658
                      s-block molecular entity 19423
                        hydrogen molecular entity 19416
                          hydrides 18755
                            organic hydride 18356
                              organic fundamental parent 18356
                                hydrocarbon 18074
                                  cyclic hydrocarbon 17089
                                    monocyclic hydrocarbon 5816
                                      annulene 5643
                                        aromatic annulene 5643
                                          benzene 5643
                                            alkylbenzene 3365
                                              ethylbenzene 102
paths to the root