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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:sepiapterin
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Accession:CHEBI:16095 term browser browse the term
Definition:A pterin that has formula C9H11N5O3.
Synonyms:exact_synonym: 2-amino-6-lactoyl-7,8-dihydropteridin-4(3H)-one
 related_synonym: 1-(2-amino-7,8-dihydro-4-hydroxypteridine-6-yl)-2-hydroxypropan-1-one;   2-amino-6-(2-hydroxypropanoyl)-7,8-dihydropteridin-4(3H)-one;   Formula=C9H11N5O3;   InChI=1S/C9H11N5O3/c1-3(15)6(16)4-2-11-7-5(12-4)8(17)14-9(10)13-7/h3,15H,2H2,1H3,(H4,10,11,13,14,17);   InChIKey=VPVOXUSPXFPWBN-UHFFFAOYSA-N;   SMILES=CC(O)C(=O)C1=Nc2c(NC1)nc(N)[nH]c2=O
 alt_id: CHEBI:15080;   CHEBI:26647;   CHEBI:9113
 xref: CAS:17094-01-8;   KEGG:C00835
 xref_mesh: MESH:C016727


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sepiapterin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gch1 GTP cyclohydrolase 1 multiple interactions EXP sepiapterin inhibits the reaction [[2,4-diaminohypoxanthine results in decreased activity of GCH1 protein] which affects the susceptibility to Calcimycin] CTD PMID:12855421 NCBI chr15:23,935,011...23,968,971
Ensembl chr15:23,934,585...23,969,011
JBrowse link
G Nos3 nitric oxide synthase 3 increases activity ISO sepiapterin results in increased activity of NOS3 protein CTD PMID:11243424 NCBI chr 4:7,321,908...7,342,404
Ensembl chr 4:7,320,668...7,342,410
JBrowse link
G Tfrc transferrin receptor decreases expression ISO sepiapterin results in decreased expression of TFRC protein CTD PMID:24964743 NCBI chr11:71,397,423...71,419,263
Ensembl chr11:71,397,383...71,419,223
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19785
    chemical entity 19785
      molecular entity 19782
        polyatomic entity 19695
          heteroatomic molecular entity 19620
            hydroxides 19066
              organic hydroxy compound 18630
                alcohol 14984
                  alpha-hydroxy ketone 8629
                    secondary alpha-hydroxy ketone 879
                      sepiapterin 3
Path 2
Term Annotations click to browse term
  CHEBI ontology 19785
    subatomic particle 19782
      composite particle 19782
        hadron 19782
          baryon 19782
            nucleon 19782
              atomic nucleus 19782
                atom 19782
                  main group element atom 19670
                    p-block element atom 19670
                      carbon group element atom 19572
                        carbon atom 19561
                          organic molecular entity 19561
                            organic group 18493
                              organic divalent group 18486
                                organodiyl group 18486
                                  carbonyl group 18389
                                    carbonyl compound 18389
                                      ketone 16140
                                        oxyketone 8629
                                          alpha-oxyketone 8629
                                            alpha-hydroxy ketone 8629
                                              secondary alpha-hydroxy ketone 879
                                                sepiapterin 3
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