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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:sepiapterin
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Accession:CHEBI:16095 term browser browse the term
Definition:A pterin that has formula C9H11N5O3.
Synonyms:exact_synonym: 2-amino-6-lactoyl-7,8-dihydropteridin-4(3H)-one
 related_synonym: 1-(2-amino-7,8-dihydro-4-hydroxypteridine-6-yl)-2-hydroxypropan-1-one;   2-amino-6-(2-hydroxypropanoyl)-7,8-dihydropteridin-4(3H)-one;   Formula=C9H11N5O3;   InChI=1S/C9H11N5O3/c1-3(15)6(16)4-2-11-7-5(12-4)8(17)14-9(10)13-7/h3,15H,2H2,1H3,(H4,10,11,13,14,17);   InChIKey=VPVOXUSPXFPWBN-UHFFFAOYSA-N;   SMILES=CC(O)C(=O)C1=Nc2c(NC1)nc(N)[nH]c2=O
 alt_id: CHEBI:15080;   CHEBI:26647;   CHEBI:9113
 xref: CAS:17094-01-8;   KEGG:C00835
 xref_mesh: MESH:C016727


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sepiapterin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gch1 GTP cyclohydrolase 1 multiple interactions EXP sepiapterin inhibits the reaction [[2,4-diaminohypoxanthine results in decreased activity of GCH1 protein] which affects the susceptibility to Calcimycin] CTD PMID:12855421 NCBI chr15:23,935,011...23,968,971
Ensembl chr15:23,934,585...23,969,011
JBrowse link
G Nos3 nitric oxide synthase 3 increases activity ISO sepiapterin results in increased activity of NOS3 protein CTD PMID:11243424 NCBI chr 4:7,321,908...7,342,404
Ensembl chr 4:7,320,668...7,342,410
JBrowse link
G Tfrc transferrin receptor decreases expression ISO sepiapterin results in decreased expression of TFRC protein CTD PMID:24964743 NCBI chr11:71,397,423...71,419,263
Ensembl chr11:71,397,383...71,419,223
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19792
    chemical entity 19791
      molecular entity 19787
        polyatomic entity 19697
          heteroatomic molecular entity 19617
            hydroxides 19091
              organic hydroxy compound 18658
                alcohol 15001
                  alpha-hydroxy ketone 8633
                    secondary alpha-hydroxy ketone 877
                      sepiapterin 3
Path 2
Term Annotations click to browse term
  CHEBI ontology 19792
    subatomic particle 19788
      composite particle 19788
        hadron 19788
          baryon 19788
            nucleon 19788
              atomic nucleus 19788
                atom 19788
                  main group element atom 19675
                    p-block element atom 19675
                      carbon group element atom 19571
                        carbon atom 19560
                          organic molecular entity 19560
                            organic group 18508
                              organic divalent group 18501
                                organodiyl group 18501
                                  carbonyl group 18404
                                    carbonyl compound 18404
                                      ketone 16152
                                        oxyketone 8633
                                          alpha-oxyketone 8633
                                            alpha-hydroxy ketone 8633
                                              secondary alpha-hydroxy ketone 877
                                                sepiapterin 3
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