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The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at The data is made available under the Creative Commons License (CC BY 3.0, For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

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Accession:CHEBI:16095 term browser browse the term
Definition:A pterin that has formula C9H11N5O3.
Synonyms:exact_synonym: 2-amino-6-lactoyl-7,8-dihydropteridin-4(3H)-one
 related_synonym: 1-(2-amino-7,8-dihydro-4-hydroxypteridine-6-yl)-2-hydroxypropan-1-one;   2-amino-6-(2-hydroxypropanoyl)-7,8-dihydropteridin-4(3H)-one;   Formula=C9H11N5O3;   InChI=1S/C9H11N5O3/c1-3(15)6(16)4-2-11-7-5(12-4)8(17)14-9(10)13-7/h3,15H,2H2,1H3,(H4,10,11,13,14,17);   InChIKey=VPVOXUSPXFPWBN-UHFFFAOYSA-N;   SMILES=CC(O)C(=O)C1=Nc2c(NC1)nc(N)[nH]c2=O
 alt_id: CHEBI:15080;   CHEBI:26647;   CHEBI:9113
 xref: CAS:17094-01-8;   KEGG:C00835
 xref_mesh: MESH:C016727

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sepiapterin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gch1 GTP cyclohydrolase 1 multiple interactions EXP sepiapterin inhibits the reaction [[2,4-diaminohypoxanthine results in decreased activity of GCH1 protein] which affects the susceptibility to Calcimycin] CTD PMID:12855421 NCBI chr15:20,404,267...20,437,727
Ensembl chr15:20,402,527...20,437,698
JBrowse link
G Nos3 nitric oxide synthase 3 increases activity ISO sepiapterin results in increased activity of NOS3 protein CTD PMID:11243424 NCBI chr 4:10,793,834...10,814,170
Ensembl chr 4:10,793,834...10,814,166
JBrowse link
G Tfrc transferrin receptor decreases expression ISO sepiapterin results in decreased expression of TFRC protein CTD PMID:24964743 NCBI chr11:68,163,413...68,185,257
Ensembl chr11:68,163,413...68,185,257
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19800
    chemical entity 19800
      molecular entity 19799
        polyatomic entity 19721
          heteroatomic molecular entity 19662
            hydroxides 19158
              organic hydroxy compound 18656
                alcohol 15085
                  alpha-hydroxy ketone 8674
                    secondary alpha-hydroxy ketone 947
                      sepiapterin 3
Path 2
Term Annotations click to browse term
  CHEBI ontology 19800
    subatomic particle 19799
      composite particle 19799
        hadron 19799
          baryon 19799
            nucleon 19799
              atomic nucleus 19799
                atom 19799
                  main group element atom 19698
                    p-block element atom 19698
                      carbon group element atom 19619
                        carbon atom 19609
                          organic molecular entity 19609
                            organic group 18718
                              organic divalent group 18702
                                organodiyl group 18702
                                  carbonyl group 18651
                                    carbonyl compound 18651
                                      ketone 16957
                                        oxyketone 8674
                                          alpha-oxyketone 8674
                                            alpha-hydroxy ketone 8674
                                              secondary alpha-hydroxy ketone 947
                                                sepiapterin 3
paths to the root