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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:prenyl diphosphate
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Accession:CHEBI:16057 term browser browse the term
Definition:A prenol phosphate that is a phosphoantigen comprising the O-pyrophosphate of prenol.
Synonyms:exact_synonym: 3-methylbut-2-en-1-yl trihydrogen diphosphate
 related_synonym: 2-Isopentenyl diphosphate;   3,3-dimethylallyl pyrophosphate;   3-methylbut-2-enyl phosphono hydrogen phosphate;   DMAPP;   Dimethylallyl diphosphate;   Dimethylallyl pyrophosphate;   Formula=C5H12O7P2;   InChI=1S/C5H12O7P2/c1-5(2)3-4-11-14(9,10)12-13(6,7)8/h3H,4H2,1-2H3,(H,9,10)(H2,6,7,8);   InChIKey=CBIDRCWHNCKSTO-UHFFFAOYSA-N;   Monoprenyl diphosphate;   Prenol pyrophosphate;   SMILES=CC(C)=CCOP(O)(=O)OP(O)(O)=O;   delta-Prenyl diphosphate;   delta2-Isopentenyl diphosphate
 alt_id: CHEBI:12280;   CHEBI:14169;   CHEBI:14883;   CHEBI:23803;   CHEBI:26245;   CHEBI:341937;   CHEBI:42074;   CHEBI:4616;   CHEBI:8394
 xref: Beilstein:1713791;   CAS:358-72-5;   DrugBank:DB01785;   KEGG:C00235;   KEGG:C17627;   KNApSAcK:C00007294;   LIPID_MAPS_instance:LMPR01010001
 xref_mesh: MESH:C043060
 xref: PDBeChem:DMA;   PMID:10608778;   PMID:11355861;   PMID:22300296;   PMID:23262281;   PMID:27356974;   Reaxys:1713791
 cyclic_relationship: is_conjugate_acid_of CHEBI:57623


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prenyl diphosphate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Il12rb1 interleukin 12 receptor subunit beta 1 increases expression ISO 3,3-dimethylallyl pyrophosphate results in increased expression of IL12RB1 protein CTD PMID:12932289 NCBI chr16:20,370,722...20,383,576
Ensembl chr16:20,371,338...20,383,337
JBrowse link
G Mvk mevalonate kinase decreases activity
multiple interactions
ISO 3,3-dimethylallyl pyrophosphate results in decreased activity of MVK protein
3,3-dimethylallyl pyrophosphate inhibits the reaction [MVK protein results in increased hydrolysis of Adenosine Triphosphate]; 3,3-dimethylallyl pyrophosphate inhibits the reaction [MVK protein results in increased phosphorylation of Mevalonic Acid]
CTD PMID:9392419 NCBI chr12:47,904,266...47,920,457
Ensembl chr12:47,904,719...47,919,400
JBrowse link
G Tnfrsf1b TNF receptor superfamily member 1B increases expression ISO 3,3-dimethylallyl pyrophosphate results in increased expression of TNFRSF1B protein CTD PMID:12932289 NCBI chr 5:163,136,390...163,167,299
Ensembl chr 5:163,136,390...163,167,299
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19787
    role 19734
      biological role 19734
        epitope 6835
          prenyl diphosphate 3
Path 2
Term Annotations click to browse term
  CHEBI ontology 19787
    subatomic particle 19784
      composite particle 19784
        hadron 19784
          baryon 19784
            nucleon 19784
              atomic nucleus 19784
                atom 19784
                  main group element atom 19672
                    p-block element atom 19672
                      chalcogen 19362
                        oxygen atom 19323
                          oxygen molecular entity 19323
                            hydroxides 19068
                              oxoacid 18193
                                pnictogen oxoacid 10146
                                  phosphorus oxoacid 9033
                                    phosphoric acids 7795
                                      phosphoric acid 7795
                                        phosphoric acid derivative 7474
                                          phosphate 7474
                                            organic phosphate 7473
                                              phospholipid 289
                                                isoprenoid phosphate 72
                                                  prenol phosphate 72
                                                    prenyl diphosphate 3
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