halide anion - Ontology Report - Rat Genome Database

2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [[Colforsin co-treated with INS protein] results in increased phosphorylation of MAPK1 protein]; 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [[Colforsin co-treated with INS protein] results in increased phosphorylation of MAPK3 protein]; [Colforsin co-treated with INS protein] results in increased phosphorylation of MAPK1 protein; [Colforsin co-treated with INS protein] results in increased phosphorylation of MAPK3 protein

PMID:12639917

NCBI chr18:46,324,047...46,324,933
Ensembl chr18:46,324,041...46,325,122

MAPK1

mitogen-activated protein kinase 1

multiple interactions

PMID:12639917

NCBI chr26:31,013,607...31,132,998
Ensembl chr26:31,013,607...31,132,998

MAPK3

mitogen-activated protein kinase 3

multiple interactions

2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [[Colforsin co-treated with INS protein] results in increased phosphorylation of MAPK3 protein]; [Colforsin co-treated with INS protein] results in increased phosphorylation of MAPK3 protein

PMID:12639917

NCBI chr 6:18,109,184...18,115,728
Ensembl chr 6:18,109,222...18,114,425

NR1I2

nuclear receptor subfamily 1 group I member 2

increases activity

Colforsin results in increased activity of NR1I2 protein

PMID:27732639

NCBI chr33:23,444,367...23,456,405
Ensembl chr33:23,432,690...23,455,347

lead(II) chloride

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

EDN1

endothelin 1

increases secretion

lead chloride results in increased secretion of EDN1 protein

PMID:15915659

NCBI chr35:11,808,892...11,815,383
Ensembl chr35:11,808,892...11,815,383

EDN2

endothelin 2

increases secretion

lead chloride results in increased secretion of EDN2 protein

PMID:15915659

NCBI chr15:1,647,966...1,654,272
Ensembl chr15:1,648,077...1,654,272

rhodamine 123

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

ABCB1

ATP binding cassette subfamily B member 1

increases export

ABCB1 protein results in increased export of Rhodamine 123

PMID:28093773

NCBI chr14:13,644,891...13,852,829
Ensembl chr14:13,542,647...13,742,727

sodium chloride

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

CLDN4

claudin 4

increases expression
multiple interactions

Sodium Chloride results in increased expression of CLDN4 protein
Acetylcysteine inhibits the reaction [Sodium Chloride results in increased expression of CLDN4 protein]; diphenyleneiodonium inhibits the reaction [Sodium Chloride results in increased expression of CLDN4 protein]; Glutathione inhibits the reaction [Sodium Chloride results in increased expression of CLDN4 protein]; manganese(III)-tetrakis(4-benzoic acid)porphyrin inhibits the reaction [Sodium Chloride results in increased expression of CLDN4 protein]; pyrazolanthrone inhibits the reaction [Sodium Chloride results in increased expression of CLDN4 protein]; U 0126 inhibits the reaction [Sodium Chloride results in increased expression of CLDN4 protein]

NCBI chr 6:6,492,706...6,506,750
Ensembl chr 6:6,493,513...6,494,145

JUN

Jun proto-oncogene, AP-1 transcription factor subunit

increases expression
multiple interactions

Sodium Chloride results in increased expression of JUN protein
pyrazolanthrone inhibits the reaction [Sodium Chloride promotes the reaction [SP1 protein binds to JUN protein]]; Sodium Chloride promotes the reaction [SP1 protein binds to JUN protein]; U 0126 inhibits the reaction [Sodium Chloride promotes the reaction [SP1 protein binds to JUN protein]]

NCBI chr 5:50,966,698...50,968,939

MAPK1

mitogen-activated protein kinase 1

increases phosphorylation
multiple interactions

Sodium Chloride results in increased phosphorylation of MAPK1 protein
Acetylcysteine inhibits the reaction [Sodium Chloride results in increased phosphorylation of MAPK1 protein]; Glutathione inhibits the reaction [Sodium Chloride results in increased phosphorylation of MAPK1 protein]; U 0126 inhibits the reaction [Sodium Chloride results in increased phosphorylation of MAPK1 protein]

NCBI chr26:31,013,607...31,132,998
Ensembl chr26:31,013,607...31,132,998

MAPK3

mitogen-activated protein kinase 3

increases phosphorylation
multiple interactions

Sodium Chloride results in increased phosphorylation of MAPK3 protein
Acetylcysteine inhibits the reaction [Sodium Chloride results in increased phosphorylation of MAPK3 protein]; Glutathione inhibits the reaction [Sodium Chloride results in increased phosphorylation of MAPK3 protein]; U 0126 inhibits the reaction [Sodium Chloride results in increased phosphorylation of MAPK3 protein]

NCBI chr 6:18,109,184...18,115,728
Ensembl chr 6:18,109,222...18,114,425

MAPK8

mitogen-activated protein kinase 8

multiple interactions
increases phosphorylation

Acetylcysteine inhibits the reaction [Sodium Chloride results in increased phosphorylation of MAPK8 protein]; Glutathione inhibits the reaction [Sodium Chloride results in increased phosphorylation of MAPK8 protein]; pyrazolanthrone inhibits the reaction [Sodium Chloride results in increased phosphorylation of MAPK8 protein]

NCBI chr28:323,361...410,367
Ensembl chr28:368,513...406,401

MAPK9

mitogen-activated protein kinase 9

multiple interactions
increases phosphorylation

Acetylcysteine inhibits the reaction [Sodium Chloride results in increased phosphorylation of MAPK9 protein]; Glutathione inhibits the reaction [Sodium Chloride results in increased phosphorylation of MAPK9 protein]; pyrazolanthrone inhibits the reaction [Sodium Chloride results in increased phosphorylation of MAPK9 protein]

NCBI chr11:1,443,528...1,480,501
Ensembl chr11:1,443,547...1,478,119

SOD2

superoxide dismutase 2

increases expression

Sodium Chloride results in increased expression of SOD2 protein

PMID:22718889

NCBI chr 1:48,943,472...48,955,158
Ensembl chr 1:48,836,262...48,955,706

SP1

Sp1 transcription factor

multiple interactions
increases expression

pyrazolanthrone inhibits the reaction [Sodium Chloride promotes the reaction [SP1 protein binds to JUN protein]]; pyrazolanthrone inhibits the reaction [Sodium Chloride results in increased expression of SP1 protein]; Sodium Chloride promotes the reaction [SP1 protein binds to JUN protein]; U 0126 inhibits the reaction [Sodium Chloride promotes the reaction [SP1 protein binds to JUN protein]]; U 0126 inhibits the reaction [Sodium Chloride results in increased expression of SP1 protein]