CHEBI ONTOLOGY - ANNOTATIONS |
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The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
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Term: | 2-ethylhexan-1-ol |
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Accession: | CHEBI:16011
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browse the term
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Definition: | A primary alcohol that is hexan-1-ol substituted by an ethyl group at position 2. |
Synonyms: | related_synonym: | 2-ethyl-1-hexanol; Formula=C8H18O; InChI=1S/C8H18O/c1-3-5-6-8(4-2)7-9/h8-9H,3-7H2,1-2H3; InChIKey=YIWUKEYIRIRTPP-UHFFFAOYSA-N; SMILES=CCCCC(CC)CO |
| alt_id: | CHEBI:1093; CHEBI:11574; CHEBI:19574 |
| xref: | CAS:104-76-7; HMDB:HMDB0031231; KEGG:C02498 |
| xref_mesh: | MESH:C034017 |
| xref: | PMID:22520499; PMID:24529788; PMID:24716585; Reaxys:1719280; Wikipedia:2-Ethylhexanol |
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Il2 |
interleukin 2 |
increases expression |
ISO |
2-ethylhexanol results in increased expression of IL2 protein |
CTD |
PMID:19038237 |
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NCBI chr 2:120,004,862...120,009,566
Ensembl chr 2:120,004,862...120,009,566
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Msx2 |
msh homeobox 2 |
increases expression |
ISO |
2-ethylhexanol results in increased expression of MSX2 mRNA |
CTD |
PMID:31445079 |
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NCBI chr17:11,097,214...11,102,879
Ensembl chr17:11,097,103...11,102,879
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Myh6 |
myosin heavy chain 6 |
decreases expression |
ISO |
2-ethylhexanol results in decreased expression of MYH6 mRNA |
CTD |
PMID:31445079 |
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NCBI chr15:28,418,120...28,442,316
Ensembl chr15:28,417,616...28,441,720
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Snai1 |
snail family transcriptional repressor 1 |
increases expression |
ISO |
2-ethylhexanol results in increased expression of SNAI1 mRNA |
CTD |
PMID:31445079 |
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NCBI chr 3:156,248,479...156,252,969
Ensembl chr 3:156,248,485...156,252,969
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Snai2 |
snail family transcriptional repressor 2 |
increases expression |
ISO |
2-ethylhexanol results in increased expression of SNAI2 mRNA |
CTD |
PMID:31445079 |
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NCBI chr11:86,183,800...86,186,109
Ensembl chr11:86,181,909...86,186,200
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Trpa1 |
transient receptor potential cation channel, subfamily A, member 1 |
increases activity |
ISO |
2-ethylhexanol results in increased activity of TRPA1 protein |
CTD |
PMID:27545873 |
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NCBI chr 5:4,379,999...4,433,243
Ensembl chr 5:4,379,999...4,433,570
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Twist1 |
twist family bHLH transcription factor 1 |
increases expression |
ISO |
2-ethylhexanol results in increased expression of TWIST1 mRNA |
CTD |
PMID:31445079 |
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NCBI chr 6:50,674,910...50,676,904
Ensembl chr 6:50,674,678...50,677,653
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Grn |
granulin precursor |
decreases expression |
EXP |
dioctyl adipate results in decreased expression of GRN mRNA |
CTD |
PMID:16493179 |
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NCBI chr10:87,387,672...87,393,777
Ensembl chr10:87,387,638...87,393,775
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Hsd11b1 |
hydroxysteroid 11-beta dehydrogenase 1 |
decreases activity |
ISO |
dioctyl adipate results in decreased activity of HSD11B1 protein |
CTD |
PMID:16184081 |
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NCBI chr13:104,728,539...104,798,884
Ensembl chr13:104,728,539...104,788,687
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Nolc1 |
nucleolar and coiled-body phosphoprotein 1 |
decreases expression |
EXP |
dioctyl adipate results in decreased expression of NOLC1 mRNA |
CTD |
PMID:16493179 |
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NCBI chr 1:244,921,275...244,932,089
Ensembl chr 1:244,921,377...244,932,088
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Abca12 |
ATP binding cassette subfamily A member 12 |
increases expression |
ISO |
mono-(2-ethylhexyl)phthalate results in increased expression of ABCA12 mRNA |
CTD |
PMID:22401849 |
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NCBI chr 9:72,822,661...72,995,748
Ensembl chr 9:72,823,350...72,996,049
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Abca4 |
ATP binding cassette subfamily A member 4 |
increases expression |
ISO |
mono-(2-ethylhexyl)phthalate results in increased expression of ABCA4 mRNA |
CTD |
PMID:22401849 |
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NCBI chr 2:210,164,813...210,302,069
Ensembl chr 2:210,164,813...210,302,069
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Abca7 |
ATP binding cassette subfamily A member 7 |
decreases expression |
ISO |
mono-(2-ethylhexyl)phthalate results in decreased expression of ABCA7 mRNA |
CTD |
PMID:22401849 |
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NCBI chr 7:9,691,452...9,711,466
Ensembl chr 7:9,691,449...9,711,425
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Abcb1b |
ATP-binding cassette, subfamily B (MDR/TAP), member 1B |
decreases expression |
ISO |
mono-(2-ethylhexyl)phthalate results in decreased expression of ABCB1B mRNA |
CTD |
PMID:22401849 |
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NCBI chr 4:25,242,761...25,325,194
Ensembl chr 4:25,242,798...25,325,199
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Abcb9 |
ATP binding cassette subfamily B member 9 |
increases expression |
ISO |
mono-(2-ethylhexyl)phthalate results in increased expression of ABCB9 mRNA |
CTD |
PMID:22401849 |
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NCBI chr12:32,499,225...32,531,932
Ensembl chr12:32,499,225...32,531,931
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Abcc10 |
ATP binding cassette subfamily C member 10 |
decreases expression |
ISO |
mono-(2-ethylhexyl)phthalate results in decreased expression of ABCC10 mRNA |
CTD |
PMID:22401849 |
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NCBI chr 9:14,657,242...14,677,178
Ensembl chr 9:14,657,264...14,677,178
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Abcc2 |
ATP binding cassette subfamily C member 2 |
affects expression |
ISO |
mono-(2-ethylhexyl)phthalate affects the expression of ABCC2 mRNA |
CTD |
PMID:22401849 |
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NCBI chr 1:242,664,657...242,723,239
Ensembl chr 1:242,664,657...242,723,238
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Abcc6 |
ATP binding cassette subfamily C member 6 |
increases expression |
ISO |
mono-(2-ethylhexyl)phthalate results in increased expression of ABCC6 mRNA |
CTD |
PMID:22401849 |
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NCBI chr 1:96,447,224...96,501,464
Ensembl chr 1:96,447,251...96,501,464
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Acaa1b |
acetyl-Coenzyme A acyltransferase 1B |
increases expression |
ISO |
mono-(2-ethylhexyl)phthalate results in increased expression of ACAA1B mRNA |
CTD |
PMID:32522588 |
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NCBI chr 8:118,872,996...118,881,852
Ensembl chr 8:118,872,997...118,881,825
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Acaa2 |
acetyl-CoA acyltransferase 2 |
increases expression |
ISO |
mono-(2-ethylhexyl)phthalate results in increased expression of ACAA2 mRNA |
CTD |
PMID:32522588 |
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NCBI chr18:68,345,136...68,373,246
Ensembl chr18:68,345,012...68,373,249
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Acadm |
acyl-CoA dehydrogenase medium chain |
increases expression |
ISO |
mono-(2-ethylhexyl)phthalate results in increased expression of ACADM mRNA |
CTD |
PMID:32522588 |
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NCBI chr 2:242,858,865...242,883,036
Ensembl chr 2:242,858,865...242,883,147
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Acads |
acyl-CoA dehydrogenase short chain |
increases expression |
EXP |
mono-(2-ethylhexyl)phthalate results in increased expression of ACADS mRNA |
CTD |
PMID:22087261 |
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NCBI chr12:41,493,650...41,502,897
Ensembl chr12:41,493,626...41,502,898
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Acap1 |
ArfGAP with coiled-coil, ankyrin repeat and PH domains 1 |
increases expression |
ISO |
mono-(2-ethylhexyl)phthalate results in increased expression of ACAP1 mRNA |
CTD |
PMID:22401849 |
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NCBI chr10:54,605,323...54,619,472
Ensembl chr10:54,605,323...54,619,472
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Acox1 |
acyl-CoA oxidase 1 |
increases expression |
EXP ISO |
mono-(2-ethylhexyl)phthalate results in increased expression of ACOX1 mRNA |
CTD |
PMID:22087261 PMID:32522588 |
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NCBI chr10:101,406,197...101,431,242
Ensembl chr10:101,406,197...101,431,232
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Acoxl |
acyl-CoA oxidase-like |
decreases expression |
ISO |
mono-(2-ethylhexyl)phthalate results in decreased expression of ACOXL mRNA |
CTD |
PMID:22401849 |
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NCBI chr 3:115,061,045...115,367,032
Ensembl chr 3:115,061,060...115,364,686
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Acsl1 |
acyl-CoA synthetase long-chain family member 1 |
increases expression |
ISO |
mono-(2-ethylhexyl)phthalate results in increased expression of ACSL1 protein |
CTD |
PMID:27384973 |
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NCBI chr16:45,755,246...45,821,541
Ensembl chr16:45,755,254...45,821,541
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Acsl4 |
acyl-CoA synthetase long-chain family member 4 |
decreases expression |
ISO |
mono-(2-ethylhexyl)phthalate results in decreased expression of ACSL4 mRNA |
CTD |
PMID:22401849 |
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NCBI chr X:105,942,794...106,006,573
Ensembl chr X:105,942,799...106,006,427
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Adam22 |
ADAM metallopeptidase domain 22 |
decreases expression |
ISO |
mono-(2-ethylhexyl)phthalate results in decreased expression of ADAM22 mRNA |
CTD |
PMID:22401849 |
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NCBI chr 4:25,716,055...25,970,932
Ensembl chr 4:25,715,990...25,964,962
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Adam23 |
ADAM metallopeptidase domain 23 |
decreases expression |
ISO |
mono-(2-ethylhexyl)phthalate results in decreased expression of ADAM23 mRNA |
CTD |
PMID:22401849 |
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NCBI chr 9:64,862,878...65,006,515
Ensembl chr 9:64,862,878...65,006,515
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Adamts20 |
ADAM metallopeptidase with thrombospondin type 1 motif, 20 |
increases expression |
ISO |
mono-(2-ethylhexyl)phthalate results in increased expression of ADAMTS20 mRNA |
CTD |
PMID:22401849 |
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NCBI chr 7:125,396,227...125,528,020
Ensembl chr 7:125,397,734...125,527,777
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Adamts4 |
ADAM metallopeptidase with thrombospondin type 1 motif, 4 |
decreases expression |
ISO |
mono-(2-ethylhexyl)phthalate results in decreased expression of ADAMTS4 mRNA |
CTD |
PMID:22401849 |
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NCBI chr13:83,670,556...83,680,045
Ensembl chr13:83,670,183...83,680,065
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Adarb2 |
adenosine deaminase, RNA-specific, B2 |
decreases expression |
ISO |
mono-(2-ethylhexyl)phthalate results in decreased expression of ADARB2 mRNA |
CTD |
PMID:22401849 |
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NCBI chr17:61,750,437...62,300,984
Ensembl chr17:61,756,067...62,300,831
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Adcy4 |
adenylate cyclase 4 |
decreases expression |
ISO |
mono-(2-ethylhexyl)phthalate results in decreased expression of ADCY4 mRNA |
CTD |
PMID:22401849 |
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NCBI chr15:29,266,280...29,282,153
Ensembl chr15:29,266,287...29,282,108
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Adcy7 |
adenylate cyclase 7 |
decreases expression |
ISO |
mono-(2-ethylhexyl)phthalate results in decreased expression of ADCY7 mRNA |
CTD |
PMID:22401849 |
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NCBI chr19:18,740,875...18,798,924
Ensembl chr19:18,740,875...18,776,311
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Adgre4 |
adhesion G protein-coupled receptor E4 |
decreases expression |
ISO |
mono-(2-ethylhexyl)phthalate results in decreased expression of ADGRE4 mRNA |
CTD |
PMID:22401849 |
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NCBI chr 9:9,758,106...9,901,908
Ensembl chr 9:9,760,355...9,900,760
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Adipoq |
adiponectin, C1Q and collagen domain containing |
increases expression |
ISO |
mono-(2-ethylhexyl)phthalate results in increased expression of ADIPOQ protein |
CTD |
PMID:27384973 |
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NCBI chr11:77,721,912...77,735,644
Ensembl chr11:77,721,912...77,735,564
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Adipor2 |
adiponectin receptor 2 |
increases expression |
ISO |
mono-(2-ethylhexyl)phthalate results in increased expression of ADIPOR2 mRNA |
CTD |
PMID:32522588 |
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NCBI chr 4:152,524,604...152,588,848
Ensembl chr 4:152,524,623...152,559,355
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Adora1 |
adenosine A1 receptor |
decreases expression |
ISO |
mono-(2-ethylhexyl)phthalate results in decreased expression of ADORA1 mRNA |
CTD |
PMID:22401849 |
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NCBI chr13:45,658,872...45,695,821
Ensembl chr13:45,658,872...45,695,801
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Adra1d |
adrenoceptor alpha 1D |
decreases expression |
ISO |
mono-(2-ethylhexyl)phthalate results in decreased expression of ADRA1D mRNA |
CTD |
PMID:22401849 |
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NCBI chr 3:118,793,356...118,809,354
Ensembl chr 3:118,793,346...118,809,354
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Afm |
afamin |
increases expression |
ISO |
mono-(2-ethylhexyl)phthalate results in increased expression of AFM mRNA |
CTD |
PMID:22401849 |
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NCBI chr14:17,531,026...17,563,868
Ensembl chr14:17,531,024...17,563,870
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Agbl3 |
AGBL carboxypeptidase 3 |
increases expression |
ISO |
mono-(2-ethylhexyl)phthalate results in increased expression of AGBL3 mRNA |
CTD |
PMID:22401849 |
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NCBI chr 4:63,448,789...63,535,538
Ensembl chr 4:63,453,940...63,531,188
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Agl |
amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase |
multiple interactions |
EXP |
mono-(2-ethylhexyl)phthalate binds to and affects the activity of AGL protein |
CTD |
PMID:19240039 |
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NCBI chr 2:204,705,053...204,760,966
Ensembl chr 2:204,705,053...204,760,828
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Agtr1b |
angiotensin II receptor, type 1b |
decreases expression |
ISO |
mono-(2-ethylhexyl)phthalate results in decreased expression of AGTR1B mRNA |
CTD |
PMID:22401849 |
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NCBI chr 2:102,844,969...102,920,232
Ensembl chr 2:102,844,969...102,920,232
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Ahcy |
adenosylhomocysteinase |
decreases expression |
ISO |
mono-(2-ethylhexyl)phthalate results in decreased expression of AHCY mRNA |
CTD |
PMID:22401849 |
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NCBI chr 3:143,569,134...143,584,359
Ensembl chr 3:143,569,094...143,584,393
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Ahr |
aryl hydrocarbon receptor |
increases expression affects expression multiple interactions |
EXP ISO |
mono-(2-ethylhexyl)phthalate results in increased expression of AHR mRNA mono-(2-ethylhexyl)phthalate affects the expression of AHR mRNA [monoethyl phthalate co-treated with mono-(2-ethylhexyl)phthalate co-treated with mono-isobutyl phthalate co-treated with monoisononylphthalate co-treated with mono-benzyl phthalate] affects the expression of AHR mRNA |
CTD |
PMID:12706301 PMID:28381288 PMID:31884101 |
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NCBI chr 6:52,234,089...52,271,568
Ensembl chr 6:52,234,089...52,271,568
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Ahrr |
aryl-hydrocarbon receptor repressor |
multiple interactions |
ISO |
[monoethyl phthalate co-treated with mono-(2-ethylhexyl)phthalate co-treated with mono-isobutyl phthalate co-treated with monoisononylphthalate co-treated with mono-benzyl phthalate] affects the expression of AHRR mRNA |
CTD |
PMID:31884101 |
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NCBI chr 1:28,993,634...29,088,673
Ensembl chr 1:28,993,634...29,088,673
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Ahsg |
alpha-2-HS-glycoprotein |
increases expression |
ISO |
mono-(2-ethylhexyl)phthalate results in increased expression of AHSG protein |
CTD |
PMID:27384973 |
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NCBI chr11:78,117,903...78,145,956
Ensembl chr11:78,117,918...78,145,999
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Aifm1 |
apoptosis inducing factor, mitochondria associated 1 |
increases expression multiple interactions |
ISO |
mono-(2-ethylhexyl)phthalate results in increased expression of AIFM1 mRNA [monoethyl phthalate co-treated with mono-(2-ethylhexyl)phthalate co-treated with mono-isobutyl phthalate co-treated with monoisononylphthalate co-treated with mono-benzyl phthalate] results in increased expression of AIFM1 mRNA; Estradiol affects the reaction [mono-(2-ethylhexyl)phthalate results in increased expression of AIFM1 mRNA] |
CTD |
PMID:24412242 PMID:31884101 |
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NCBI chr X:127,650,223...127,689,356
Ensembl chr X:127,650,226...127,689,256
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Aifm3 |
apoptosis inducing factor, mitochondria associated 3 |
increases expression |
ISO |
mono-(2-ethylhexyl)phthalate results in increased expression of AIFM3 mRNA |
CTD |
PMID:22401849 |
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NCBI chr11:83,504,859...83,523,630
Ensembl chr11:83,504,861...83,521,248
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Ajuba |
ajuba LIM protein |
increases expression |
EXP |
mono-(2-ethylhexyl)phthalate results in increased expression of AJUBA mRNA |
CTD |
PMID:16809437 |
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NCBI chr15:28,019,775...28,031,537
Ensembl chr15:28,019,778...28,030,021
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Akt1 |
AKT serine/threonine kinase 1 |
multiple interactions affects response to substance increases activity increases phosphorylation |
ISO EXP |
AKT1 protein affects the reaction [mono-(2-ethylhexyl)phthalate results in increased expression of BCL2L1 mRNA]; AKT1 protein affects the reaction [mono-(2-ethylhexyl)phthalate results in increased expression of BCL2L1 protein]; AKT1 protein affects the reaction [mono-(2-ethylhexyl)phthalate results in increased expression of NFKB1 mRNA]; mono-(2-ethylhexyl)phthalate inhibits the reaction [INS protein results in increased expression of and results in increased phosphorylation of AKT1 protein] AKT1 protein affects the susceptibility to mono-(2-ethylhexyl)phthalate mono-(2-ethylhexyl)phthalate results in increased activity of AKT1 protein mono-(2-ethylhexyl)phthalate results in increased phosphorylation of AKT1 protein mono-(2-ethylhexyl)phthalate inhibits the reaction [INS1 protein results in increased phosphorylation of AKT1 protein] [bisphenol A co-treated with mono-(2-ethylhexyl)phthalate] results in increased phosphorylation of AKT1 protein; HDAC6 protein affects the reaction [[bisphenol A co-treated with mono-(2-ethylhexyl)phthalate] results in increased phosphorylation of AKT1 protein] |
CTD |
PMID:18755736 PMID:28526321 PMID:31009676 PMID:34910997 |
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NCBI chr 6:131,713,716...131,735,319
Ensembl chr 6:131,713,720...131,733,921
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Akt1s1 |
AKT1 substrate 1 |
decreases expression |
ISO |
mono-(2-ethylhexyl)phthalate results in decreased expression of AKT1S1 mRNA |
CTD |
PMID:22401849 |
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NCBI chr 1:95,333,186...95,339,678
Ensembl chr 1:95,332,898...95,339,677
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Alpl |
alkaline phosphatase, biomineralization associated |
decreases expression |
ISO |
mono-(2-ethylhexyl)phthalate analog results in decreased expression of ALPL protein; mono-(2-ethylhexyl)phthalate results in decreased expression of ALPL protein |
CTD |
PMID:25777084 |
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NCBI chr 5:149,951,397...150,006,424
Ensembl chr 5:149,951,409...150,006,446
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Amh |
anti-Mullerian hormone |
decreases expression |
ISO EXP |
mono-(2-ethylhexyl)phthalate results in decreased expression of AMH mRNA mono-(2-ethylhexyl)phthalate results in decreased expression of AMH protein |
CTD |
PMID:19165384 PMID:19440488 |
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NCBI chr 7:8,906,776...8,909,184
Ensembl chr 7:8,906,836...8,909,282
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Ank1 |
ankyrin 1 |
increases expression |
ISO |
mono-(2-ethylhexyl)phthalate results in increased expression of ANK1 mRNA |
CTD |
PMID:22401849 |
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NCBI chr16:68,876,294...69,054,812
Ensembl chr16:68,877,504...69,054,759
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Ano9 |
anoctamin 9 |
increases expression |
ISO |
mono-(2-ethylhexyl)phthalate results in increased expression of ANO9 mRNA |
CTD |
PMID:22401849 |
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NCBI chr 1:196,208,863...196,230,381
Ensembl chr 1:196,197,341...196,229,900
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Antxr2 |
ANTXR cell adhesion molecule 2 |
decreases expression |
ISO |
mono-(2-ethylhexyl)phthalate results in decreased expression of ANTXR2 mRNA |
CTD |
PMID:22401849 |
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NCBI chr14:11,542,266...11,682,112
Ensembl chr14:11,541,772...11,682,094
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Aox1 |
aldehyde oxidase 1 |
increases expression |
ISO |
mono-(2-ethylhexyl)phthalate results in increased expression of AOX1 mRNA |
CTD |
PMID:23360888 |
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NCBI chr 9:59,579,621...59,658,772
Ensembl chr 9:59,579,649...59,658,770
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Apln |
apelin |
affects expression |
ISO |
mono-(2-ethylhexyl)phthalate affects the expression of APLN mRNA |
CTD |
PMID:32522588 |
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NCBI chr X:127,180,801...127,213,567
Ensembl chr X:127,203,823...127,213,391
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Apoe |
apolipoprotein E |
increases expression |
EXP |
mono-(2-ethylhexyl)phthalate results in increased expression of APOE mRNA |
CTD |
PMID:22087261 |
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NCBI chr 1:79,353,924...79,357,852
Ensembl chr 1:79,353,916...79,357,932
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Ar |
androgen receptor |
multiple interactions |
ISO |
mono-(2-ethylhexyl)phthalate inhibits the reaction [cyclopamine results in increased expression of AR] [monoethyl phthalate co-treated with mono-(2-ethylhexyl)phthalate co-treated with mono-isobutyl phthalate co-treated with monoisononylphthalate co-treated with mono-benzyl phthalate] results in decreased expression of AR mRNA |
CTD |
PMID:26710974 PMID:31884101 |
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NCBI chr X:63,104,771...63,273,934
Ensembl chr X:63,104,771...63,273,925
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Arnt |
aryl hydrocarbon receptor nuclear translocator |
multiple interactions |
ISO |
[monoethyl phthalate co-treated with mono-(2-ethylhexyl)phthalate co-treated with mono-isobutyl phthalate co-treated with monoisononylphthalate co-treated with mono-benzyl phthalate] affects the expression of ARNT mRNA |
CTD |
PMID:31884101 |
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NCBI chr 2:182,997,731...183,056,584
Ensembl chr 2:182,997,736...183,056,580
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G |
Arrb2 |
arrestin, beta 2 |
multiple interactions |
EXP |
mono-(2-ethylhexyl)phthalate inhibits the reaction [INS1 protein results in increased expression of ARRB2 protein] |
CTD |
PMID:28526321 |
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NCBI chr10:55,146,887...55,154,854
Ensembl chr10:55,146,818...55,154,850
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G |
Arrdc3 |
arrestin domain containing 3 |
increases expression |
ISO |
mono-(2-ethylhexyl)phthalate results in increased expression of ARRDC3 mRNA |
CTD |
PMID:24356939 |
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NCBI chr 2:11,137,443...11,149,978
Ensembl chr 2:11,137,460...11,149,978
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G |
Artn |
artemin |
increases expression |
ISO |
mono-(2-ethylhexyl)phthalate results in increased expression of ARTN mRNA |
CTD |
PMID:22401849 |
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NCBI chr 5:131,458,596...131,470,193
Ensembl chr 5:131,464,756...131,468,025
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G |
Ascc3 |
activating signal cointegrator 1 complex subunit 3 |
decreases expression |
ISO |
mono-(2-ethylhexyl)phthalate results in decreased expression of ASCC3 mRNA |
CTD |
PMID:22401849 |
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NCBI chr20:53,510,137...53,795,446
Ensembl chr20:53,510,184...53,790,165
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G |
Atf3 |
activating transcription factor 3 |
increases expression |
EXP |
mono-(2-ethylhexyl)phthalate results in increased expression of ATF3 mRNA |
CTD |
PMID:16809437 |
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NCBI chr13:102,751,278...102,800,520
Ensembl chr13:102,751,321...102,764,631
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G |
Atf7ip2 |
activating transcription factor 7 interacting protein 2 |
increases expression |
ISO |
mono-(2-ethylhexyl)phthalate results in increased expression of ATF7IP2 mRNA |
CTD |
PMID:22401849 |
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NCBI chr10:5,403,099...5,445,989
Ensembl chr10:5,403,105...5,446,142
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G |
Atp12a |
ATPase H+/K+ transporting non-gastric alpha2 subunit |
decreases expression |
ISO |
mono-(2-ethylhexyl)phthalate results in decreased expression of ATP12A mRNA |
CTD |
PMID:22401849 |
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NCBI chr15:30,443,571...30,468,229
Ensembl chr15:30,443,571...30,468,229
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G |
Atp13a4 |
ATPase 13A4 |
increases expression |
ISO |
mono-(2-ethylhexyl)phthalate results in increased expression of ATP13A4 mRNA |
CTD |
PMID:22401849 |
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NCBI chr11:71,222,196...71,359,933
Ensembl chr11:71,226,161...71,359,933
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G |
Atp1a3 |
ATPase Na+/K+ transporting subunit alpha 3 |
decreases expression |
ISO |
mono-(2-ethylhexyl)phthalate results in decreased expression of ATP1A3 mRNA |
CTD |
PMID:22401849 |
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NCBI chr 1:80,572,790...80,601,936
Ensembl chr 1:80,572,796...80,601,918
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G |
Atp6v1c2 |
ATPase H+ transporting V1 subunit C2 |
increases expression |
ISO |
mono-(2-ethylhexyl)phthalate results in increased expression of ATP6V1C2 mRNA |
CTD |
PMID:22401849 |
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NCBI chr 6:40,080,545...40,144,199
Ensembl chr 6:40,080,547...40,120,028
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G |
Atp6v1h |
ATPase H+ transporting V1 subunit H |
affects expression |
ISO |
mono-(2-ethylhexyl)phthalate affects the expression of ATP6V1H mRNA |
CTD |
PMID:21195148 |
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NCBI chr 5:14,379,029...14,484,703
Ensembl chr 5:14,378,257...14,537,962
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G |
Atp8b4 |
ATPase phospholipid transporting 8B4 (putative) |
decreases expression |
ISO |
mono-(2-ethylhexyl)phthalate results in decreased expression of ATP8B4 mRNA |
CTD |
PMID:22401849 |
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NCBI chr 3:113,554,979...113,757,635
Ensembl chr 3:113,556,192...113,757,225
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G |
Atp9b |
ATPase phospholipid transporting 9B (putative) |
increases expression |
ISO |
mono-(2-ethylhexyl)phthalate results in increased expression of ATP9B mRNA |
CTD |
PMID:22401849 |
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NCBI chr18:74,176,863...74,368,993
Ensembl chr18:74,176,863...74,368,953
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G |
Atrnl1 |
attractin like 1 |
increases expression |
ISO |
mono-(2-ethylhexyl)phthalate results in increased expression of ATRNL1 mRNA |
CTD |
PMID:22401849 |
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NCBI chr 1:256,670,976...257,219,291
Ensembl chr 1:256,670,627...257,213,197
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G |
Avpi1 |
arginine vasopressin-induced 1 |
decreases expression |
ISO |
mono-(2-ethylhexyl)phthalate results in decreased expression of AVPI1 mRNA |
CTD |
PMID:22401849 |
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NCBI chr 1:240,930,236...240,936,154
Ensembl chr 1:240,930,236...240,936,154
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G |
B3galt1 |
Beta-1,3-galactosyltransferase 1 |
increases expression |
EXP |
mono-(2-ethylhexyl)phthalate results in increased expression of B3GALT1 mRNA |
CTD |
PMID:16809437 |
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NCBI chr 3:52,253,413...52,826,508
Ensembl chr 3:52,253,618...52,825,313
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G |
B3galt2 |
Beta-1,3-galactosyltransferase 2 |
decreases expression |
ISO |
mono-(2-ethylhexyl)phthalate results in decreased expression of B3GALT2 mRNA |
CTD |
PMID:22401849 |
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NCBI chr13:55,389,406...55,398,419
Ensembl chr13:55,389,406...55,398,419
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G |
Bax |
BCL2 associated X, apoptosis regulator |
increases expression multiple interactions |
ISO |
mono-(2-ethylhexyl)phthalate results in increased expression of BAX mRNA; mono-(2-ethylhexyl)phthalate results in increased expression of BAX protein [monoethyl phthalate co-treated with mono-(2-ethylhexyl)phthalate co-treated with mono-isobutyl phthalate co-treated with monoisononylphthalate co-treated with mono-benzyl phthalate] results in increased expression of BAX mRNA |
CTD |
PMID:12927354 PMID:24706461 PMID:26597031 PMID:31884101 |
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NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368
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G |
Baz1a |
bromodomain adjacent to zinc finger domain, 1A |
decreases expression |
ISO |
mono-(2-ethylhexyl)phthalate results in decreased expression of BAZ1A mRNA |
CTD |
PMID:22401849 |
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NCBI chr 6:72,389,701...72,512,516
Ensembl chr 6:72,389,703...72,512,459
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G |
Bbc3 |
Bcl-2 binding component 3 |
increases expression |
ISO |
mono-(2-ethylhexyl)phthalate results in increased expression of BBC3 protein |
CTD |
PMID:24706461 |
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NCBI chr 1:77,013,281...77,022,509
Ensembl chr 1:77,014,543...77,022,509
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G |
Bcl2 |
BCL2, apoptosis regulator |
decreases expression multiple interactions |
ISO |
mono-(2-ethylhexyl)phthalate results in decreased expression of BCL2 mRNA; mono-(2-ethylhexyl)phthalate results in decreased expression of BCL2 protein [mono-(2-ethylhexyl)phthalate co-treated with Estradiol] results in decreased expression of BCL2 mRNA; [monoethyl phthalate co-treated with mono-(2-ethylhexyl)phthalate co-treated with mono-isobutyl phthalate co-treated with monoisononylphthalate co-treated with mono-benzyl phthalate] affects the expression of BCL2 mRNA MIR16-1 mRNA affects the reaction [mono-(2-ethylhexyl)phthalate results in decreased expression of BCL2 protein] |
CTD |
PMID:12927354 PMID:24412242 PMID:24706461 PMID:26597031 PMID:31884101 |
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NCBI chr13:22,689,783...22,853,920
Ensembl chr13:22,684,989...22,853,743 Ensembl chr13:22,684,989...22,853,743
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G |
Bcl2l1 |
Bcl2-like 1 |
multiple interactions increases expression |
ISO |
AKT1 protein affects the reaction [mono-(2-ethylhexyl)phthalate results in increased expression of BCL2L1 mRNA]; AKT1 protein affects the reaction [mono-(2-ethylhexyl)phthalate results in increased expression of BCL2L1 protein] mono-(2-ethylhexyl)phthalate results in increased expression of BCL2L1 mRNA; mono-(2-ethylhexyl)phthalate results in increased expression of BCL2L1 protein |
CTD |
PMID:18755736 |
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NCBI chr 3:141,253,508...141,304,582
Ensembl chr 3:141,253,523...141,303,479
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G |
Bcl2l10 |
Bcl2-like 10 |
multiple interactions decreases expression |
ISO |
[monoethyl phthalate co-treated with mono-(2-ethylhexyl)phthalate co-treated with mono-isobutyl phthalate co-treated with monoisononylphthalate co-treated with mono-benzyl phthalate] results in decreased expression of BCL2L10 mRNA; Estradiol affects the reaction [mono-(2-ethylhexyl)phthalate results in decreased expression of BCL2L10 mRNA] |
CTD |
PMID:24412242 PMID:31884101 |
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NCBI chr 8:76,107,326...76,113,373
Ensembl chr 8:76,107,326...76,113,367
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G |
Bcl6 |
BCL6, transcription repressor |
increases expression |
EXP |
mono-(2-ethylhexyl)phthalate results in increased expression of BCL6 mRNA |
CTD |
PMID:16809437 |
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NCBI chr11:76,854,090...76,877,389
Ensembl chr11:76,854,090...76,877,389
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G |
Bean1 |
brain expressed, associated with NEDD4, 1 |
decreases expression |
ISO |
mono-(2-ethylhexyl)phthalate results in decreased expression of BEAN1 mRNA |
CTD |
PMID:22401849 |
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NCBI chr19:739,551...786,122
Ensembl chr19:739,551...787,537
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G |
Bhmt |
betaine-homocysteine S-methyltransferase |
decreases expression |
ISO |
mono-(2-ethylhexyl)phthalate results in decreased expression of BHMT mRNA |
CTD |
PMID:22401849 |
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NCBI chr 2:24,859,871...24,879,449
Ensembl chr 2:24,859,873...24,879,742
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G |
Bicra |
BRD4 interacting chromatin remodeling complex associated protein |
decreases expression |
ISO |
mono-(2-ethylhexyl)phthalate results in decreased expression of BICRA mRNA |
CTD |
PMID:22401849 |
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NCBI chr 1:76,661,897...76,736,146
Ensembl chr 1:76,661,897...76,737,157
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G |
Bid |
BH3 interacting domain death agonist |
multiple interactions |
ISO |
[monoethyl phthalate co-treated with mono-(2-ethylhexyl)phthalate co-treated with mono-isobutyl phthalate co-treated with monoisononylphthalate co-treated with mono-benzyl phthalate] results in increased expression of BID mRNA |
CTD |
PMID:31884101 |
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NCBI chr 4:154,113,198...154,136,353
Ensembl chr 4:154,113,198...154,134,720
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G |
Bok |
BCL2 family apoptosis regulator BOK |
decreases expression multiple interactions |
ISO |
mono-(2-ethylhexyl)phthalate results in decreased expression of BOK mRNA [monoethyl phthalate co-treated with mono-(2-ethylhexyl)phthalate co-treated with mono-isobutyl phthalate co-treated with monoisononylphthalate co-treated with mono-benzyl phthalate] results in decreased expression of BOK mRNA |
CTD |
PMID:24412242 PMID:31884101 |
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NCBI chr 9:94,223,493...94,234,476
Ensembl chr 9:94,223,389...94,234,476
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G |
Bpifb6 |
BPI fold containing family B, member 6 |
decreases expression |
ISO |
mono-(2-ethylhexyl)phthalate results in decreased expression of BPIFB6 mRNA |
CTD |
PMID:22401849 |
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NCBI chr 3:142,383,701...142,395,308
Ensembl chr 3:142,381,374...142,395,308
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G |
Brd3 |
bromodomain containing 3 |
increases expression |
ISO |
mono-(2-ethylhexyl)phthalate results in increased expression of BRD3 mRNA |
CTD |
PMID:22401849 |
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NCBI chr 3:10,773,163...10,829,675
Ensembl chr 3:10,775,272...10,829,577
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G |
Brsk1 |
BR serine/threonine kinase 1 |
decreases expression |
ISO |
mono-(2-ethylhexyl)phthalate results in decreased expression of BRSK1 mRNA |
CTD |
PMID:22401849 |
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NCBI chr 1:69,134,166...69,159,947
Ensembl chr 1:69,134,565...69,160,365
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G |
Btg2 |
BTG anti-proliferation factor 2 |
increases expression |
EXP |
mono-(2-ethylhexyl)phthalate results in increased expression of BTG2 mRNA |
CTD |
PMID:16809437 |
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NCBI chr13:45,531,881...45,535,642
Ensembl chr13:45,531,925...45,535,628
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G |
Bves |
blood vessel epicardial substance |
decreases expression |
ISO |
mono-(2-ethylhexyl)phthalate results in decreased expression of BVES mRNA |
CTD |
PMID:22401849 |
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NCBI chr20:48,819,241...48,860,282
Ensembl chr20:48,822,308...48,857,472
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G |
C1qtnf6 |
C1q and TNF related 6 |
decreases expression |
ISO |
mono-(2-ethylhexyl)phthalate results in decreased expression of C1QTNF6 mRNA |
CTD |
PMID:22401849 |
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NCBI chr 7:110,077,867...110,084,584
Ensembl chr 7:110,077,878...110,084,412
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G |
C8a |
complement C8 alpha chain |
increases expression |
ISO |
mono-(2-ethylhexyl)phthalate results in increased expression of C8A mRNA |
CTD |
PMID:22401849 |
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NCBI chr 5:119,583,168...119,637,675
Ensembl chr 5:119,583,174...119,637,754
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G |
Cabp1 |
calcium binding protein 1 |
decreases expression |
ISO |
mono-(2-ethylhexyl)phthalate results in decreased expression of CABP1 mRNA |
CTD |
PMID:22401849 |
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NCBI chr12:41,385,234...41,448,930
Ensembl chr12:41,378,897...41,448,927
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G |
Cadm1 |
cell adhesion molecule 1 |
affects expression |
ISO |
mono-(2-ethylhexyl)phthalate affects the expression of CADM1 mRNA |
CTD |
PMID:21195148 |
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NCBI chr 8:47,847,836...48,178,703
Ensembl chr 8:47,847,325...48,182,833
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G |
Camk1d |
calcium/calmodulin-dependent protein kinase ID |
increases expression |
ISO |
mono-(2-ethylhexyl)phthalate results in increased expression of CAMK1D mRNA |
CTD |
PMID:22401849 |
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NCBI chr17:72,581,899...72,982,704
Ensembl chr17:72,581,979...72,980,556
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G |
Casp3 |
caspase 3 |
multiple interactions increases expression increases activity increases cleavage |
ISO EXP |
2,2-bis(4-glycidyloxyphenyl)propane inhibits the reaction [PPARG protein promotes the reaction [mono-(2-ethylhexyl)phthalate results in increased activity of CASP3 protein]]; 2-chloro-5-nitrobenzanilide inhibits the reaction [PPARG protein promotes the reaction [mono-(2-ethylhexyl)phthalate results in increased activity of CASP3 protein]]; PPARG protein promotes the reaction [mono-(2-ethylhexyl)phthalate results in increased activity of CASP3 protein]; rosiglitazone promotes the reaction [PPARG protein promotes the reaction [mono-(2-ethylhexyl)phthalate results in increased activity of CASP3 protein]] mono-(2-ethylhexyl)phthalate results in increased expression of CASP3 protein mono-(2-ethylhexyl)phthalate results in increased cleavage of CASP3 protein [monoethyl phthalate co-treated with mono-(2-ethylhexyl)phthalate co-treated with mono-isobutyl phthalate co-treated with monoisononylphthalate co-treated with mono-benzyl phthalate] results in decreased expression of CASP3 mRNA |
CTD |
PMID:12927354 PMID:19165384 PMID:19720108 PMID:23360888 PMID:24706461 PMID:30476341 PMID:31884101 More...
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NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648
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G |
Casp7 |
caspase 7 |
increases activity |
ISO |
mono-(2-ethylhexyl)phthalate results in increased activity of CASP7 protein |
CTD |
PMID:23360888 |
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NCBI chr 1:255,437,195...255,476,737
Ensembl chr 1:255,437,172...255,476,729
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G |
Casp8 |
caspase 8 |
multiple interactions |
ISO |
[monoethyl phthalate co-treated with mono-(2-ethylhexyl)phthalate co-treated with mono-isobutyl phthalate co-treated with monoisononylphthalate co-treated with mono-benzyl phthalate] results in decreased expression of CASP8 mRNA |
CTD |
PMID:31884101 |
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NCBI chr 9:60,263,863...60,312,542
Ensembl chr 9:60,264,075...60,312,542
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G |
Casp9 |
caspase 9 |
increases activity |
ISO |
mono-(2-ethylhexyl)phthalate results in increased activity of CASP9 protein |
CTD |
PMID:24706461 |
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NCBI chr 5:154,108,872...154,126,628
Ensembl chr 5:154,109,046...154,126,626
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G |
Cat |
catalase |
multiple interactions increases expression increases activity |
EXP ISO |
Cycloheximide inhibits the reaction [mono-(2-ethylhexyl)phthalate results in increased expression of CAT protein] [monoethyl phthalate co-treated with mono-(2-ethylhexyl)phthalate co-treated with mono-isobutyl phthalate co-treated with monoisononylphthalate co-treated with mono-benzyl phthalate] results in increased expression of CAT mRNA mono-(2-ethylhexyl)phthalate results in increased activity of CAT protein |
CTD |
PMID:2306265 PMID:6845354 PMID:31884101 PMID:32522588 |
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NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478
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G |
Cbr1 |
carbonyl reductase 1 |
multiple interactions |
ISO |
[mono-(2-ethylhexyl)phthalate co-treated with Genistein] results in increased expression of CBR1 mRNA |
CTD |
PMID:34942354 |
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NCBI chr11:32,860,618...32,862,981
Ensembl chr11:32,908,950...32,911,393 Ensembl chr11:32,908,950...32,911,393
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G |
Cbs |
cystathionine beta synthase |
affects expression |
ISO |
mono-(2-ethylhexyl)phthalate affects the expression of CBS mRNA |
CTD |
PMID:21195148 |
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NCBI chr20:9,708,089...9,732,623
Ensembl chr20:9,708,090...9,732,764
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G |
Ccdc27 |
coiled-coil domain containing 27 |
increases expression |
ISO |
mono-(2-ethylhexyl)phthalate results in increased expression of CCDC27 mRNA |
CTD |
PMID:22401849 |
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NCBI chr 5:164,585,285...164,599,391
Ensembl chr 5:164,585,267...164,599,355
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G |
Ccdc96 |
coiled-coil domain containing 96 |
affects expression |
ISO |
mono-(2-ethylhexyl)phthalate affects the expression of CCDC96 mRNA |
CTD |
PMID:21195148 |
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NCBI chr14:74,276,568...74,279,072
Ensembl chr14:74,276,960...74,278,888
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G |
Ccl2 |
C-C motif chemokine ligand 2 |
increases expression |
ISO |
mono-(2-ethylhexyl)phthalate results in increased expression of CCL2 mRNA |
CTD |
PMID:27384973 |
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NCBI chr10:67,005,424...67,007,222
Ensembl chr10:67,005,424...67,007,226
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G |
Ccn1 |
cellular communication network factor 1 |
increases expression |
EXP |
mono-(2-ethylhexyl)phthalate results in increased expression of CCN1 mRNA |
CTD |
PMID:16809437 |
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NCBI chr 2:234,562,410...234,565,370
Ensembl chr 2:234,562,408...234,565,484
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G |
Ccn2 |
cellular communication network factor 2 |
increases expression |
EXP |
mono-(2-ethylhexyl)phthalate results in increased expression of CCN2 mRNA |
CTD |
PMID:16809437 |
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NCBI chr 1:20,802,199...20,805,315
Ensembl chr 1:20,802,199...20,805,734
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G |
Ccna2 |
cyclin A2 |
multiple interactions |
ISO |
[monoethyl phthalate co-treated with mono-(2-ethylhexyl)phthalate co-treated with mono-isobutyl phthalate co-treated with monoisononylphthalate co-treated with mono-benzyl phthalate] results in decreased expression of CCNA2 mRNA |
CTD |
PMID:31884101 |
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NCBI chr 2:119,427,239...119,433,645
Ensembl chr 2:119,426,089...119,433,577
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G |
Ccnb1 |
cyclin B1 |
multiple interactions |
ISO |
[monoethyl phthalate co-treated with mono-(2-ethylhexyl)phthalate co-treated with mono-isobutyl phthalate co-treated with monoisononylphthalate co-treated with mono-benzyl phthalate] results in decreased expression of CCNB1 mRNA |
CTD |
PMID:31884101 |
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NCBI chr 2:31,912,190...31,921,163
Ensembl chr 2:31,912,193...31,921,172
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G |
Ccnb2 |
cyclin B2 |
multiple interactions |
ISO |
[monoethyl phthalate co-treated with mono-(2-ethylhexyl)phthalate co-treated with mono-isobutyl phthalate co-treated with monoisononylphthalate co-treated with mono-benzyl phthalate] results in decreased expression of CCNB2 mRNA |
CTD |
PMID:31884101 |
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NCBI chr 8:71,087,594...71,100,794
Ensembl chr 8:71,087,595...71,100,874
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G |
Ccnd1 |
cyclin D1 |
affects expression |
ISO |
mono-(2-ethylhexyl)phthalate affects the expression of CCND1 mRNA |
CTD |
PMID:21195148 |
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NCBI chr 1:200,089,002...200,098,524
Ensembl chr 1:200,089,002...200,098,602
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G |
Ccnd2 |
cyclin D2 |
multiple interactions decreases expression |
ISO |
Estradiol inhibits the reaction [mono-(2-ethylhexyl)phthalate results in decreased expression of CCND2 mRNA] |
CTD |
PMID:19874833 |
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NCBI chr 4:159,966,883...159,989,261
Ensembl chr 4:159,962,363...159,989,495
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G |
Ccnd3 |
cyclin D3 |
multiple interactions |
ISO |
[monoethyl phthalate co-treated with mono-(2-ethylhexyl)phthalate co-treated with mono-isobutyl phthalate co-treated with monoisononylphthalate co-treated with mono-benzyl phthalate] results in decreased expression of CCND3 mRNA |
CTD |
PMID:31884101 |
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NCBI chr 9:13,394,161...13,400,341
Ensembl chr 9:13,394,169...13,489,371
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G |
Ccne1 |
cyclin E1 |
multiple interactions |
ISO |
[monoethyl phthalate co-treated with mono-(2-ethylhexyl)phthalate co-treated with mono-isobutyl phthalate co-treated with monoisononylphthalate co-treated with mono-benzyl phthalate] results in decreased expression of CCNE1 mRNA |
CTD |
PMID:31884101 |
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NCBI chr 1:90,781,947...90,791,188
Ensembl chr 1:90,781,949...90,791,101
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G |
Ccno |
cyclin O |
affects expression |
ISO |
mono-(2-ethylhexyl)phthalate affects the expression of CCNO mRNA |
CTD |
PMID:21195148 |
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NCBI chr 2:44,630,640...44,633,914
Ensembl chr 2:44,626,369...44,633,914
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G |
Ccr7 |
C-C motif chemokine receptor 7 |
multiple interactions |
ISO |
[bisphenol A co-treated with mono-(2-ethylhexyl)phthalate co-treated with mono-benzyl phthalate co-treated with monobutyl phthalate] results in increased expression of CCR7 mRNA |
CTD |
PMID:30398665 |
|
NCBI chr10:84,098,193...84,108,309
Ensembl chr10:84,097,381...84,108,309
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G |
Ccrl2 |
C-C motif chemokine receptor like 2 |
increases expression decreases expression |
EXP ISO |
mono-(2-ethylhexyl)phthalate results in increased expression of CCRL2 mRNA mono-(2-ethylhexyl)phthalate results in decreased expression of CCRL2 mRNA |
CTD |
PMID:16809437 PMID:22401849 |
|
NCBI chr 8:111,034,279...111,036,914
Ensembl chr 8:111,034,279...111,036,664
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G |
Cd109 |
CD109 molecule |
affects expression decreases expression |
ISO |
mono-(2-ethylhexyl)phthalate affects the expression of CD109 mRNA mono-(2-ethylhexyl)phthalate results in decreased expression of CD109 mRNA |
CTD |
PMID:21195148 PMID:22401849 |
|
NCBI chr 8:79,454,480...79,569,195
Ensembl chr 8:79,454,480...79,569,194
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G |
Cd163 |
CD163 molecule |
increases expression multiple interactions |
ISO |
mono-(2-ethylhexyl)phthalate results in increased expression of CD163 protein [bisphenol A co-treated with mono-(2-ethylhexyl)phthalate co-treated with mono-benzyl phthalate co-treated with monobutyl phthalate] results in decreased expression of CD163 mRNA mono-(2-ethylhexyl)phthalate inhibits the reaction [[Lipopolysaccharides co-treated with IFNG protein] results in increased expression of CD163 mRNA] |
CTD |
PMID:22143055 PMID:29718165 PMID:30398665 |
|
NCBI chr 4:157,085,080...157,118,470
Ensembl chr 4:157,085,093...157,117,878
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G |
Cd24 |
CD24 molecule |
affects expression |
ISO |
mono-(2-ethylhexyl)phthalate affects the expression of CD24A mRNA |
CTD |
PMID:21195148 |
|
NCBI chr20:47,074,353...47,079,662
Ensembl chr20:47,073,512...47,079,662
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G |
Cd36 |
CD36 molecule |
multiple interactions increases expression |
ISO |
mono-(2-ethylhexyl)phthalate inhibits the reaction [[Lipopolysaccharides co-treated with IFNG protein] results in increased expression of CD36 mRNA] mono-(2-ethylhexyl)phthalate results in increased expression of CD36 mRNA |
CTD |
PMID:29718165 PMID:35421560 |
|
NCBI chr 4:17,317,343...17,410,084
Ensembl chr 4:17,354,466...17,513,903
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G |
Cd40 |
CD40 molecule |
affects expression |
ISO |
mono-(2-ethylhexyl)phthalate affects the expression of CD40 mRNA |
CTD |
PMID:21195148 |
|
NCBI chr 3:153,790,372...153,805,279
Ensembl chr 3:153,790,449...153,805,534
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G |
Cd69 |
Cd69 molecule |
increases expression |
EXP |
mono-(2-ethylhexyl)phthalate results in increased expression of CD69 mRNA |
CTD |
PMID:16809437 |
|
NCBI chr 4:162,725,446...162,733,364
Ensembl chr 4:162,725,446...162,733,542
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G |
Cdh2 |
cadherin 2 |
multiple interactions |
EXP |
[Ascorbic Acid co-treated with Vitamin E] inhibits the reaction [mono-(2-ethylhexyl)phthalate affects the localization of CDH2 protein]; mono-(2-ethylhexyl)phthalate results in increased expression of and affects the localization of CDH2 protein |
CTD |
PMID:29940330 |
|
NCBI chr18:7,776,704...7,990,934
Ensembl chr18:7,776,704...7,990,167
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G |
Cdh23 |
cadherin-related 23 |
increases expression |
ISO |
mono-(2-ethylhexyl)phthalate results in increased expression of CDH23 mRNA |
CTD |
PMID:22401849 |
|
NCBI chr20:28,240,643...28,622,490
Ensembl chr20:28,240,645...28,622,419
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G |
Cdhr2 |
cadherin-related family member 2 |
decreases expression |
ISO |
mono-(2-ethylhexyl)phthalate results in decreased expression of CDHR2 mRNA |
CTD |
PMID:22401849 |
|
NCBI chr17:9,876,853...9,913,356
Ensembl chr17:9,876,860...9,912,575
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G |
Cdk2 |
cyclin dependent kinase 2 |
multiple interactions |
ISO |
[monoethyl phthalate co-treated with mono-(2-ethylhexyl)phthalate co-treated with mono-isobutyl phthalate co-treated with monoisononylphthalate co-treated with mono-benzyl phthalate] results in decreased expression of CDK2 mRNA |
CTD |
PMID:31884101 |
|
NCBI chr 7:1,129,878...1,137,431
Ensembl chr 7:1,129,811...1,137,403
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G |
Cdk4 |
cyclin-dependent kinase 4 |
decreases expression multiple interactions |
ISO |
mono-(2-ethylhexyl)phthalate results in decreased expression of CDK4 mRNA [monoethyl phthalate co-treated with mono-(2-ethylhexyl)phthalate co-treated with mono-isobutyl phthalate co-treated with monoisononylphthalate co-treated with mono-benzyl phthalate] results in decreased expression of CDK4 mRNA; Estradiol inhibits the reaction [mono-(2-ethylhexyl)phthalate results in decreased expression of CDK4 mRNA] |
CTD |
PMID:19874833 PMID:31884101 |
|
NCBI chr 7:62,885,647...62,889,562
Ensembl chr 7:62,883,105...62,942,403
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G |
Cdkn1a |
cyclin-dependent kinase inhibitor 1A |
decreases expression multiple interactions increases activity |
ISO |
mono-(2-ethylhexyl)phthalate results in decreased expression of CDKN1A mRNA [monoethyl phthalate co-treated with mono-(2-ethylhexyl)phthalate co-treated with mono-isobutyl phthalate co-treated with monoisononylphthalate co-treated with mono-benzyl phthalate] results in increased expression of CDKN1A mRNA Selenomethionine inhibits the reaction [mono-(2-ethylhexyl)phthalate results in increased activity of CDKN1A protein]; Sodium Selenite inhibits the reaction [mono-(2-ethylhexyl)phthalate results in increased activity of CDKN1A protein] |
CTD |
PMID:21515331 PMID:22401849 PMID:31884101 |
|
NCBI chr20:7,149,177...7,159,727
Ensembl chr20:7,149,217...7,159,585
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G |
Cdkn1b |
cyclin-dependent kinase inhibitor 1B |
multiple interactions |
ISO |
[monoethyl phthalate co-treated with mono-(2-ethylhexyl)phthalate co-treated with mono-isobutyl phthalate co-treated with monoisononylphthalate co-treated with mono-benzyl phthalate] results in decreased expression of CDKN1B mRNA |
CTD |
PMID:31884101 |
|
NCBI chr 4:167,760,067...167,765,177
Ensembl chr 4:167,760,181...167,764,982
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G |
Cdkn1c |
cyclin-dependent kinase inhibitor 1C |
multiple interactions |
ISO |
[monoethyl phthalate co-treated with mono-(2-ethylhexyl)phthalate co-treated with mono-isobutyl phthalate co-treated with monoisononylphthalate co-treated with mono-benzyl phthalate] results in decreased expression of CDKN1C mRNA |
CTD |
PMID:31884101 |
|
NCBI chr 1:198,655,394...198,658,097
Ensembl chr 1:198,655,407...198,658,048
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G |
Cdkn2a |
cyclin-dependent kinase inhibitor 2A |
multiple interactions |
ISO |
[monoethyl phthalate co-treated with mono-(2-ethylhexyl)phthalate co-treated with mono-isobutyl phthalate co-treated with monoisononylphthalate co-treated with mono-benzyl phthalate] results in increased expression of CDKN2A mRNA |
CTD |
PMID:31884101 |
|
NCBI chr 5:103,984,949...103,992,143
Ensembl chr 5:103,984,949...104,003,149
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G |
Cdkn2b |
cyclin-dependent kinase inhibitor 2B |
multiple interactions |
ISO |
[monoethyl phthalate co-treated with mono-(2-ethylhexyl)phthalate co-treated with mono-isobutyl phthalate co-treated with monoisononylphthalate co-treated with mono-benzyl phthalate] results in increased expression of CDKN2B mRNA |
CTD |
PMID:31884101 |
|
NCBI chr 5:104,009,839...104,019,082
Ensembl chr 5:104,010,680...104,019,050
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G |
Cdkn2c |
cyclin-dependent kinase inhibitor 2C |
multiple interactions |
ISO |
[monoethyl phthalate co-treated with mono-(2-ethylhexyl)phthalate co-treated with mono-isobutyl phthalate co-treated with monoisononylphthalate co-treated with mono-benzyl phthalate] results in decreased expression of CDKN2C mRNA |
CTD |
PMID:31884101 |
|
NCBI chr 5:124,411,123...124,416,278
Ensembl chr 5:124,411,124...124,416,278
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G |
Cdkn2d |
cyclin dependent kinase inhibitor 2D |
multiple interactions |
ISO |
[monoethyl phthalate co-treated with mono-(2-ethylhexyl)phthalate co-treated with mono-isobutyl phthalate co-treated with monoisononylphthalate co-treated with mono-benzyl phthalate] affects the expression of CDKN2D mRNA |
CTD |
PMID:31884101 |
|
NCBI chr 8:19,831,874...19,834,640
Ensembl chr 8:19,831,866...19,834,674
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G |
Cdo1 |
cysteine dioxygenase type 1 |
increases expression |
EXP |
mono-(2-ethylhexyl)phthalate results in increased expression of CDO1 mRNA |
CTD |
PMID:16809437 |
|
NCBI chr18:39,432,473...39,447,253
Ensembl chr18:39,432,474...39,447,296
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G |
Cebpa |
CCAAT/enhancer binding protein alpha |
decreases expression multiple interactions increases expression |
ISO EXP |
mono-(2-ethylhexyl)phthalate results in decreased expression of CEBPA protein Colforsin inhibits the reaction [mono-(2-ethylhexyl)phthalate results in decreased expression of CEBPA protein] mono-(2-ethylhexyl)phthalate results in increased expression of CEBPA mRNA |
CTD |
PMID:21832167 PMID:25543134 PMID:27384973 |
|
NCBI chr 1:87,759,631...87,762,303
Ensembl chr 1:87,759,433...87,762,412
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G |
Cebpb |
CCAAT/enhancer binding protein beta |
increases expression |
ISO |
mono-(2-ethylhexyl)phthalate results in increased expression of CEBPB mRNA |
CTD |
PMID:25543134 |
|
NCBI chr 3:156,398,035...156,399,466
Ensembl chr 3:156,397,052...156,399,473
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G |
Celsr2 |
cadherin, EGF LAG seven-pass G-type receptor 2 |
multiple interactions increases phosphorylation affects transport |
ISO |
[IC 261 results in decreased activity of CSNK1A1 protein] inhibits the reaction [mono-(2-ethylhexyl)phthalate results in increased phosphorylation of CELSR2 protein] mono-(2-ethylhexyl)phthalate affects the transport of CELSR2 protein |
CTD |
PMID:16484285 |
|
NCBI chr 2:196,029,206...196,053,848
Ensembl chr 2:196,029,434...196,053,845
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G |
Cflar |
CASP8 and FADD-like apoptosis regulator |
multiple interactions |
ISO |
[FASL affects the susceptibility to mono-(2-ethylhexyl)phthalate] which affects the expression of CFLAR protein |
CTD |
PMID:20100735 |
|
NCBI chr 9:60,185,338...60,236,173
Ensembl chr 9:60,185,452...60,237,034
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G |
Cga |
glycoprotein hormones, alpha polypeptide |
multiple interactions affects expression increases expression increases secretion |
ISO |
mono-(2-ethylhexyl)phthalate inhibits the reaction [CGA protein results in increased abundance of Estradiol] mono-(2-ethylhexyl)phthalate affects the expression of CGA mRNA mono-(2-ethylhexyl)phthalate results in increased expression of CGA mRNA mono-(2-ethylhexyl)phthalate results in increased secretion of CGA protein mono-(2-ethylhexyl)phthalate inhibits the reaction [CGA protein results in increased abundance of Progesterone] |
CTD |
PMID:19501113 PMID:27181934 PMID:28381288 PMID:29089286 |
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NCBI chr 5:49,486,915...49,499,192
Ensembl chr 5:49,487,068...49,499,191
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G |
Chat |
choline O-acetyltransferase |
increases expression |
EXP |
mono-(2-ethylhexyl)phthalate results in increased expression of CHAT mRNA |
CTD |
PMID:21145954 |
|
NCBI chr16:7,657,362...7,717,093
Ensembl chr16:7,657,362...7,717,093
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G |
Chd5 |
chromodomain helicase DNA binding protein 5 |
increases expression |
ISO |
mono-(2-ethylhexyl)phthalate results in increased expression of CHD5 mRNA |
CTD |
PMID:22401849 |
|
NCBI chr 5:162,848,273...162,898,997
Ensembl chr 5:162,848,394...162,896,291
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G |
Chek2 |
checkpoint kinase 2 |
increases phosphorylation multiple interactions |
ISO |
mono-(2-ethylhexyl)phthalate results in increased phosphorylation of CHEK2 protein gingerol inhibits the reaction [mono-(2-ethylhexyl)phthalate results in increased phosphorylation of CHEK2 protein] |
CTD |
PMID:28988496 |
|
NCBI chr12:45,788,823...45,821,382
Ensembl chr12:45,788,827...45,821,286
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G |
Chrd |
chordin |
affects expression |
ISO |
mono-(2-ethylhexyl)phthalate affects the expression of CHRD mRNA |
CTD |
PMID:21195148 |
|
NCBI chr11:80,171,994...80,181,166
Ensembl chr11:80,171,994...80,180,673
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G |
Chrna9 |
cholinergic receptor nicotinic alpha 9 subunit |
affects expression |
ISO |
mono-(2-ethylhexyl)phthalate affects the expression of CHRNA9 mRNA |
CTD |
PMID:21195148 |
|
NCBI chr14:42,235,218...42,241,939
Ensembl chr14:42,235,226...42,242,192
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G |
Cidea |
cell death-inducing DFFA-like effector a |
increases expression |
ISO |
mono-(2-ethylhexyl)phthalate results in increased expression of CIDEA mRNA |
CTD |
PMID:32522588 |
|
NCBI chr18:60,894,917...60,920,485
Ensembl chr18:60,894,874...60,920,481
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G |
Clasp2 |
cytoplasmic linker associated protein 2 |
decreases expression |
ISO |
mono-(2-ethylhexyl)phthalate results in decreased expression of CLASP2 mRNA |
CTD |
PMID:22401849 |
|
NCBI chr 8:113,677,345...113,859,957
Ensembl chr 8:113,677,284...113,858,731
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G |
Cldn18 |
claudin 18 |
decreases expression |
ISO |
mono-(2-ethylhexyl)phthalate results in decreased expression of CLDN18 mRNA |
CTD |
PMID:22401849 |
|
NCBI chr 8:100,246,499...100,265,797
Ensembl chr 8:100,247,633...100,273,351
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G |
Cldn6 |
claudin 6 |
increases expression |
ISO |
mono-(2-ethylhexyl)phthalate results in increased expression of CLDN6 mRNA |
CTD |
PMID:22321834 |
|
NCBI chr10:12,710,302...12,713,987
Ensembl chr10:12,709,960...12,715,973
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G |
Clstn3 |
calsyntenin 3 |
decreases expression |
ISO |
mono-(2-ethylhexyl)phthalate results in decreased expression of CLSTN3 mRNA |
CTD |
PMID:22401849 |
|
NCBI chr 4:157,331,494...157,364,769
Ensembl chr 4:157,331,494...157,364,769
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G |
Cmtm2b |
CKLF-like MARVEL transmembrane domain containing 2B |
decreases expression |
ISO |
mono-(2-ethylhexyl)phthalate results in decreased expression of CMTM2B mRNA |
CTD |
PMID:22401849 |
|
NCBI chr19:640,837...651,872
Ensembl chr19:640,824...651,939
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G |
Cnga2 |
cyclic nucleotide gated channel subunit alpha 2 |
increases expression |
ISO |
mono-(2-ethylhexyl)phthalate results in increased expression of CNGA2 mRNA |
CTD |
PMID:22401849 |
|
NCBI chr X:149,696,999...149,715,051
Ensembl chr X:149,696,997...149,715,051
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G |
Cnga4 |
cyclic nucleotide gated channel subunit alpha 4 |
increases expression |
ISO |
mono-(2-ethylhexyl)phthalate results in increased expression of CNGA4 mRNA |
CTD |
PMID:22401849 |
|
NCBI chr 1:159,752,357...159,756,369
Ensembl chr 1:159,752,357...159,756,375
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G |
Cntn3 |
contactin 3 |
decreases expression |
ISO |
mono-(2-ethylhexyl)phthalate results in decreased expression of CNTN3 mRNA |
CTD |
PMID:22401849 |
|
NCBI chr 4:134,841,268...135,214,460
Ensembl chr 4:134,842,266...135,125,613
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G |
Cntnap5b |
contactin associated protein family member 5B |
decreases expression |
ISO |
mono-(2-ethylhexyl)phthalate results in decreased expression of CNTNAP5A mRNA |
CTD |
PMID:22401849 |
|
NCBI chr13:17,863,367...18,766,983
Ensembl chr13:18,093,420...18,761,014
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G |
Cntrl |
centriolin |
increases expression |
ISO |
mono-(2-ethylhexyl)phthalate results in increased expression of CNTRL mRNA |
CTD |
PMID:22401849 |
|
NCBI chr 3:18,428,147...18,500,362
Ensembl chr 3:18,428,103...18,500,380
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G |
Col12a1 |
collagen type XII alpha 1 chain |
decreases expression |
ISO |
mono-(2-ethylhexyl)phthalate results in decreased expression of COL12A1 mRNA |
CTD |
PMID:22401849 |
|
NCBI chr 8:80,547,592...80,665,665
Ensembl chr 8:80,547,593...80,665,686
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G |
Col25a1 |
collagen type XXV alpha 1 chain |
increases expression |
ISO |
mono-(2-ethylhexyl)phthalate results in increased expression of COL25A1 mRNA |
CTD |
PMID:22401849 |
|
NCBI chr 2:218,755,152...219,154,348
Ensembl chr 2:218,755,691...219,153,501
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G |
Col2a1 |
collagen type II alpha 1 chain |
increases expression |
ISO |
mono-(2-ethylhexyl)phthalate results in increased expression of COL2A1 mRNA |
CTD |
PMID:22401849 |
|
NCBI chr 7:129,098,489...129,127,620
Ensembl chr 7:129,098,786...129,127,546
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G |
Col4a6 |
collagen type IV alpha 6 chain |
increases expression |
ISO |
mono-(2-ethylhexyl)phthalate results in increased expression of COL4A6 mRNA |
CTD |
PMID:22401849 |
|
NCBI chr X:104,766,463...105,117,499
Ensembl chr X:104,766,957...105,117,500
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G |
Cox7a1 |
cytochrome c oxidase subunit 7A1 |
increases expression |
ISO |
mono-(2-ethylhexyl)phthalate results in increased expression of COX7A1 mRNA |
CTD |
PMID:32522588 |
|
NCBI chr 1:85,422,162...85,447,530
Ensembl chr 1:85,441,871...85,445,151
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G |
Cpa5 |
carboxypeptidase A5 |
decreases expression |
ISO |
mono-(2-ethylhexyl)phthalate results in decreased expression of CPA5 mRNA |
CTD |
PMID:22401849 |
|
NCBI chr 4:59,229,754...59,249,503
Ensembl chr 4:59,230,964...59,249,490
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G |
Cpt1a |
carnitine palmitoyltransferase 1A |
decreases expression affects expression |
ISO |
mono-(2-ethylhexyl)phthalate results in decreased expression of CPT1A mRNA mono-(2-ethylhexyl)phthalate affects the expression of CPT1A mRNA |
CTD |
PMID:22401849 PMID:32522588 |
|
NCBI chr 1:200,564,634...200,627,059
Ensembl chr 1:200,565,613...200,627,055
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G |
Cpt2 |
carnitine palmitoyltransferase 2 |
increases expression |
ISO |
mono-(2-ethylhexyl)phthalate results in increased expression of CPT2 mRNA |
CTD |
PMID:32522588 |
|
NCBI chr 5:122,664,677...122,682,126
Ensembl chr 5:122,664,677...122,682,095
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G |
Crhbp |
corticotropin releasing hormone binding protein |
decreases expression |
ISO |
mono-(2-ethylhexyl)phthalate results in decreased expression of CRHBP mRNA |
CTD |
PMID:22401849 |
|
NCBI chr 2:26,692,403...26,704,710
Ensembl chr 2:26,692,403...26,704,710
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G |
Crhr2 |
corticotropin releasing hormone receptor 2 |
increases expression |
ISO |
mono-(2-ethylhexyl)phthalate results in increased expression of CRHR2 mRNA |
CTD |
PMID:22401849 |
|
NCBI chr 4:84,222,897...84,265,924
Ensembl chr 4:84,224,002...84,265,904
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G |
Csnk1a1 |
casein kinase 1, alpha 1 |
multiple interactions |
ISO |
[IC 261 results in decreased activity of CSNK1A1 protein] inhibits the reaction [mono-(2-ethylhexyl)phthalate results in increased phosphorylation of CELSR2 protein] |
CTD |
PMID:16484285 |
|
NCBI chr18:55,017,049...55,050,184
Ensembl chr18:55,017,055...55,049,271
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G |
Cth |
cystathionine gamma-lyase |
affects expression |
ISO |
mono-(2-ethylhexyl)phthalate affects the expression of CTH mRNA |
CTD |
PMID:21195148 |
|
NCBI chr 2:246,975,888...247,002,234
Ensembl chr 2:246,975,894...247,002,234
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G |
Ctnnb1 |
catenin beta 1 |
increases expression multiple interactions |
ISO EXP |
mono-(2-ethylhexyl)phthalate results in increased expression of CTNNB1 mRNA [Ascorbic Acid co-treated with Vitamin E] inhibits the reaction [mono-(2-ethylhexyl)phthalate affects the localization of CTNNB1 protein]; mono-(2-ethylhexyl)phthalate results in increased expression of and affects the localization of CTNNB1 protein |
CTD |
PMID:22321834 PMID:29940330 |
|
NCBI chr 8:120,640,008...120,667,110
Ensembl chr 8:120,639,995...120,667,111
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G |
Ctsl |
cathepsin L |
increases expression |
EXP |
mono-(2-ethylhexyl)phthalate results in increased expression of CTSL mRNA |
CTD |
PMID:16809437 |
|
NCBI chr17:764,370...770,533
Ensembl chr17:764,309...770,548
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|
G |
Cubn |
cubilin |
decreases expression |
ISO |
mono-(2-ethylhexyl)phthalate results in decreased expression of CUBN mRNA |
CTD |
PMID:22401849 |
|
NCBI chr17:76,385,046...76,593,133
Ensembl chr17:76,385,060...76,593,231
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G |
Cxcl1 |
C-X-C motif chemokine ligand 1 |
increases expression |
EXP |
mono-(2-ethylhexyl)phthalate results in increased expression of CXCL1 mRNA |
CTD |
PMID:16809437 |
|
NCBI chr14:17,193,364...17,195,143
Ensembl chr14:17,193,365...17,195,215
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|
G |
Cxcl10 |
C-X-C motif chemokine ligand 10 |
increases expression multiple interactions |
EXP ISO |
mono-(2-ethylhexyl)phthalate results in increased expression of CXCL10 mRNA [bisphenol A co-treated with mono-(2-ethylhexyl)phthalate co-treated with mono-benzyl phthalate co-treated with monobutyl phthalate] results in increased expression of CXCL10 mRNA |
CTD |
PMID:16809437 PMID:30398665 |
|
NCBI chr14:15,704,772...15,706,969
Ensembl chr14:15,704,758...15,706,975
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|
G |
Cxcl3 |
C-X-C motif chemokine ligand 3 |
increases expression |
ISO |
mono-(2-ethylhexyl)phthalate results in increased expression of CXCL1 mRNA |
CTD |
PMID:27384973 |
|
NCBI chr14:17,270,146...17,289,458
Ensembl chr14:17,270,146...17,289,511
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|
G |
Cyc1 |
cytochrome c-1 |
increases expression |
ISO |
mono-(2-ethylhexyl)phthalate results in increased expression of CYC1 mRNA |
CTD |
PMID:32522588 |
|
NCBI chr 7:108,067,106...108,069,483
Ensembl chr 7:108,067,115...108,069,479
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Cycs |
cytochrome c, somatic |
affects expression |
ISO |
mono-(2-ethylhexyl)phthalate affects the expression of CYCS mRNA |
CTD |
PMID:32522588 |
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NCBI chr 4:79,651,894...79,653,994
Ensembl chr 4:79,651,378...79,654,054
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G |
Cyp11a1 |
cytochrome P450, family 11, subfamily a, polypeptide 1 |
increases activity increases expression multiple interactions decreases expression |
EXP ISO |
mono-(2-ethylhexyl)phthalate results in increased activity of CYP11A1 protein mono-(2-ethylhexyl)phthalate results in increased expression of CYP11A1 mRNA [Genistein co-treated with mono-(2-ethylhexyl)phthalate] results in increased expression of CYP11A1 mRNA; [monoethyl phthalate co-treated with mono-(2-ethylhexyl)phthalate co-treated with mono-isobutyl phthalate co-treated with monoisononylphthalate co-treated with mono-benzyl phthalate] results in decreased expression of CYP11A1 mRNA mono-(2-ethylhexyl)phthalate results in decreased expression of CYP11A1 mRNA; mono-(2-ethylhexyl)phthalate results in decreased expression of CYP11A1 protein |
CTD |
PMID:22401849 PMID:22525294 PMID:27181934 PMID:29089286 PMID:31884101 PMID:34627990 More...
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NCBI chr 8:58,422,807...58,434,342
Ensembl chr 8:58,404,669...58,434,338
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Cyp17a1 |
cytochrome P450, family 17, subfamily a, polypeptide 1 |
increases expression affects expression decreases expression multiple interactions |
EXP ISO |
mono-(2-ethylhexyl)phthalate results in increased expression of CYP17A1 mRNA mono-(2-ethylhexyl)phthalate affects the expression of CYP17A1 mono-(2-ethylhexyl)phthalate results in decreased expression of CYP17A1 mRNA; mono-(2-ethylhexyl)phthalate results in decreased expression of CYP17A1 protein [monoethyl phthalate co-treated with mono-(2-ethylhexyl)phthalate co-treated with mono-isobutyl phthalate co-treated with monoisononylphthalate co-treated with mono-benzyl phthalate] results in decreased expression of CYP17A1 mRNA |
CTD |
PMID:16809437 PMID:19560483 PMID:22087261 PMID:31884101 |
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NCBI chr 1:245,535,462...245,543,148
Ensembl chr 1:245,535,462...245,541,573
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Cyp19a1 |
cytochrome P450, family 19, subfamily a, polypeptide 1 |
decreases activity multiple interactions decreases expression increases expression |
ISO EXP |
mono-(2-ethylhexyl)phthalate results in decreased activity of CYP19A1 protein mono-(2-ethylhexyl)phthalate inhibits the reaction [Colforsin results in increased expression of CYP19A1 mRNA] mono-(2-ethylhexyl)phthalate results in decreased expression of CYP19A1 mRNA alitretinoin promotes the reaction [mono-(2-ethylhexyl)phthalate results in decreased expression of CYP19A1 mRNA] mono-(2-ethylhexyl)phthalate results in increased expression of CYP19A1 mRNA [monoethyl phthalate co-treated with mono-(2-ethylhexyl)phthalate co-treated with mono-isobutyl phthalate co-treated with monoisononylphthalate co-treated with mono-benzyl phthalate] results in decreased expression of CYP19A1 mRNA |
CTD |
PMID:12706301 PMID:19501113 PMID:19822197 PMID:19874833 PMID:22401849 PMID:29089286 PMID:31884101 More...
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NCBI chr 8:54,553,165...54,580,758
Ensembl chr 8:54,553,165...54,580,758
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G |
Cyp1a1 |
cytochrome P450, family 1, subfamily a, polypeptide 1 |
increases expression multiple interactions decreases expression |
ISO |
mono-(2-ethylhexyl)phthalate results in increased expression of CYP1A1 mRNA [monoethyl phthalate co-treated with mono-(2-ethylhexyl)phthalate co-treated with mono-isobutyl phthalate co-treated with monoisononylphthalate co-treated with mono-benzyl phthalate] results in increased expression of CYP1A1 mRNA mono-(2-ethylhexyl)phthalate results in decreased expression of CYP1A1 mRNA |
CTD |
PMID:15521013 PMID:31884101 PMID:34954075 |
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NCBI chr 8:58,096,021...58,102,130
Ensembl chr 8:58,096,077...58,102,125
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G |
Cyp1b1 |
cytochrome P450, family 1, subfamily b, polypeptide 1 |
increases expression multiple interactions decreases expression |
EXP ISO |
mono-(2-ethylhexyl)phthalate results in increased expression of CYP1B1 mRNA 2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [mono-(2-ethylhexyl)phthalate results in decreased expression of CYP1B1 mRNA]; [monoethyl phthalate co-treated with mono-(2-ethylhexyl)phthalate co-treated with mono-isobutyl phthalate co-treated with monoisononylphthalate co-treated with mono-benzyl phthalate] results in decreased expression of CYP1B1 mRNA |
CTD |
PMID:12706301 PMID:31884101 PMID:34954075 |
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NCBI chr 6:15,342,312...15,350,886
Ensembl chr 6:15,342,344...15,350,917
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G |
Cyp2c11 |
cytochrome P450, subfamily 2, polypeptide 11 |
decreases activity multiple interactions increases metabolic processing |
EXP ISO |
mono-(2-ethylhexyl)phthalate results in decreased activity of CYP2C11 protein [CYP2C9 protein polymorphism results in increased metabolism of mono-(2-ethylhexyl)phthalate] which results in increased chemical synthesis of 2-ethyl-5-carboxypentyl phthalate; [CYP2C9 protein polymorphism results in increased metabolism of mono-(2-ethylhexyl)phthalate] which results in increased chemical synthesis of mono(2-ethyl-5-hydroxyhexyl) phthalate; [CYP2C9 protein polymorphism results in increased metabolism of mono-(2-ethylhexyl)phthalate] which results in increased chemical synthesis of mono(2-ethyl-5-oxohexyl)phthalate; [CYP2C9 protein polymorphism results in increased metabolism of mono-(2-ethylhexyl)phthalate] which results in increased chemical synthesis of phthalic acid; [CYP2C9 protein results in increased metabolism of mono-(2-ethylhexyl)phthalate] which results in increased chemical synthesis of mono(2-ethyl-5-hydroxyhexyl) phthalate; [CYP2C9 protein results in increased metabolism of mono-(2-ethylhexyl)phthalate] which results in increased chemical synthesis of mono(2-ethyl-5-oxohexyl)phthalate CYP2C9 protein polymorphism results in increased metabolism of mono-(2-ethylhexyl)phthalate; CYP2C9 protein results in increased metabolism of mono-(2-ethylhexyl)phthalate |
CTD |
PMID:22186153 PMID:23545481 PMID:27432241 |
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NCBI chr 1:236,762,719...236,799,069
Ensembl chr 1:236,762,842...236,799,066
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Cyp2c6v1 |
cytochrome P450, family 2, subfamily C, polypeptide 6, variant 1 |
increases metabolic processing multiple interactions |
EXP ISO |
CYP2C6V1 protein results in increased metabolism of mono-(2-ethylhexyl)phthalate [CYP2C19 protein results in increased metabolism of mono-(2-ethylhexyl)phthalate] which results in increased chemical synthesis of mono(2-ethyl-5-hydroxyhexyl) phthalate; [CYP2C19 protein results in increased metabolism of mono-(2-ethylhexyl)phthalate] which results in increased chemical synthesis of mono(2-ethyl-5-oxohexyl)phthalate [CYP2C6V1 protein results in increased metabolism of mono-(2-ethylhexyl)phthalate] which results in increased chemical synthesis of mono(2-ethyl-5-hydroxyhexyl) phthalate; [CYP2C6V1 protein results in increased metabolism of mono-(2-ethylhexyl)phthalate] which results in increased chemical synthesis of mono(2-ethyl-5-oxohexyl)phthalate; [CYP2C6V1 protein results in increased metabolism of mono-(2-ethylhexyl)phthalate] which results in increased chemical synthesis of phthalic acid |
CTD |
PMID:22186153 PMID:23545481 |
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NCBI chr 1:237,938,521...237,976,238
Ensembl chr 1:237,693,094...238,057,596
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Cyp3a2 |
cytochrome P450, family 3, subfamily a, polypeptide 2 |
increases metabolic processing multiple interactions increases expression |
EXP ISO |
CYP3A2 protein results in increased metabolism of mono-(2-ethylhexyl)phthalate CYP3A4 protein results in increased metabolism of mono-(2-ethylhexyl)phthalate [CYP3A4 protein results in increased metabolism of mono-(2-ethylhexyl)phthalate] which results in increased chemical synthesis of mono(2-ethyl-5-hydroxyhexyl) phthalate; [CYP3A4 protein results in increased metabolism of mono-(2-ethylhexyl)phthalate] which results in increased chemical synthesis of mono(2-ethyl-5-oxohexyl)phthalate; [CYP3A4 protein results in increased metabolism of mono-(2-ethylhexyl)phthalate] which results in increased chemical synthesis of phthalic acid; [Dexamethasone co-treated with mono-(2-ethylhexyl)phthalate] results in increased activity of CYP3A4 protein mono-(2-ethylhexyl)phthalate results in increased expression of CYP3A4 mRNA [CYP3A2 protein results in increased metabolism of mono-(2-ethylhexyl)phthalate] which results in increased chemical synthesis of mono(2-ethyl-5-hydroxyhexyl) phthalate; [CYP3A2 protein results in increased metabolism of mono-(2-ethylhexyl)phthalate] which results in increased chemical synthesis of mono(2-ethyl-5-oxohexyl)phthalate; [CYP3A2 protein results in increased metabolism of mono-(2-ethylhexyl)phthalate] which results in increased chemical synthesis of phthalic acid |
CTD |
PMID:18332045 PMID:22186153 PMID:23545481 PMID:27551952 |
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NCBI chr12:9,207,986...9,230,038
Ensembl chr12:9,015,383...9,285,008
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G |
Cyp3a62 |
cytochrome P450, family 3, subfamily a, polypeptide 62 |
decreases activity |
EXP |
mono-(2-ethylhexyl)phthalate results in decreased activity of CYP3A62 protein |
CTD |
PMID:27432241 |
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NCBI chr12:16,397,998...16,433,833
Ensembl chr12:16,397,998...16,433,833
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G |
Cyp51 |
cytochrome P450, family 51 |
decreases expression |
EXP |
mono-(2-ethylhexyl)phthalate results in decreased expression of CYP51 mRNA |
CTD |
PMID:22087261 |
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NCBI chr 4:30,036,956...30,055,410
Ensembl chr 4:30,036,865...30,055,410
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G |
Dach1 |
dachshund family transcription factor 1 |
increases expression |
ISO |
mono-(2-ethylhexyl)phthalate results in increased expression of DACH1 mRNA |
CTD |
PMID:22401849 |
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NCBI chr15:74,528,122...74,909,811
Ensembl chr15:74,529,208...74,909,922
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G |
Ddit3 |
DNA-damage inducible transcript 3 |
increases expression |
ISO |
mono-(2-ethylhexyl)phthalate results in increased expression of DDIT3 mRNA |
CTD |
PMID:22321834 |
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NCBI chr 7:63,115,645...63,121,203
Ensembl chr 7:63,116,380...63,121,201
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G |
Ddx4 |
DEAD-box helicase 4 |
decreases expression |
EXP |
mono-(2-ethylhexyl)phthalate results in decreased expression of DDX4 mRNA |
CTD |
PMID:30476341 |
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NCBI chr 2:44,227,946...44,282,867
Ensembl chr 2:44,227,946...44,282,723
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G |
Derl3 |
derlin 3 |
affects expression |
ISO |
mono-(2-ethylhexyl)phthalate affects the expression of DERL3 mRNA |
CTD |
PMID:21195148 |
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NCBI chr20:12,754,490...12,768,454
Ensembl chr20:12,763,543...12,767,027
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G |
Dgkb |
diacylglycerol kinase, beta |
decreases expression |
ISO |
mono-(2-ethylhexyl)phthalate results in decreased expression of DGKB mRNA |
CTD |
PMID:22401849 |
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NCBI chr 6:54,640,948...55,397,210
Ensembl chr 6:54,641,614...55,397,043
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G |
Dhcr24 |
24-dehydrocholesterol reductase |
decreases expression |
ISO |
mono-(2-ethylhexyl)phthalate results in decreased expression of DHCR24 mRNA |
CTD |
PMID:23360888 |
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NCBI chr 5:121,344,637...121,368,853
Ensembl chr 5:121,344,575...121,371,137
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G |
Dhcr7 |
7-dehydrocholesterol reductase |
affects expression decreases expression |
EXP ISO |
mono-(2-ethylhexyl)phthalate affects the expression of DHCR7; mono-(2-ethylhexyl)phthalate affects the expression of DHCR7 mRNA mono-(2-ethylhexyl)phthalate results in decreased expression of DHCR7 mRNA |
CTD |
PMID:16809437 PMID:19560483 PMID:22401849 |
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NCBI chr 1:199,015,081...199,031,055
Ensembl chr 1:199,015,081...199,031,055
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G |
Dhrs4 |
dehydrogenase/reductase 4 |
increases expression |
ISO |
mono-(2-ethylhexyl)phthalate results in increased expression of DHRS4 protein |
CTD |
PMID:27384973 |
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NCBI chr15:28,966,544...28,978,135
Ensembl chr15:28,966,553...28,978,127
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Diablo |
diablo, IAP-binding mitochondrial protein |
decreases expression increases expression |
ISO |
mono-(2-ethylhexyl)phthalate results in decreased expression of DIABLO mRNA mono-(2-ethylhexyl)phthalate results in increased expression of DIABLO protein |
CTD |
PMID:18755736 PMID:24706461 |
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NCBI chr12:33,055,784...33,070,400
Ensembl chr12:33,055,263...33,070,387
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G |
Dipk2a |
divergent protein kinase domain 2A |
increases expression |
EXP |
mono-(2-ethylhexyl)phthalate results in increased expression of DIPK2A mRNA |
CTD |
PMID:16809437 |
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NCBI chr 8:95,070,695...95,089,815
Ensembl chr 8:95,030,279...95,089,815
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G |
Disp3 |
dispatched RND transporter family member 3 |
decreases expression |
ISO |
mono-(2-ethylhexyl)phthalate results in decreased expression of DISP3 mRNA |
CTD |
PMID:22401849 |
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NCBI chr 5:158,672,015...158,720,806
Ensembl chr 5:158,672,015...158,720,806
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Dmd |
dystrophin |
increases expression |
ISO |
mono-(2-ethylhexyl)phthalate results in increased expression of DMD mRNA |
CTD |
PMID:22401849 |
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NCBI chr X:47,272,324...49,504,219
Ensembl chr X:47,272,331...49,504,207
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G |
Dmp1 |
dentin matrix acidic phosphoprotein 1 |
decreases expression |
ISO |
mono-(2-ethylhexyl)phthalate results in decreased expression of DMP1 mRNA |
CTD |
PMID:25777084 |
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NCBI chr14:5,528,441...5,542,078
Ensembl chr14:5,528,431...5,539,323
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G |
Dnah14 |
dynein axonemal heavy chain 14 |
increases expression |
ISO |
mono-(2-ethylhexyl)phthalate results in increased expression of DNAH14 mRNA |
CTD |
PMID:22401849 |
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NCBI chr13:93,322,653...93,540,706
Ensembl chr13:93,322,711...93,538,646
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G |
Dnah8 |
dynein, axonemal, heavy chain 8 |
increases expression |
ISO |
mono-(2-ethylhexyl)phthalate results in increased expression of DNAH8 mRNA |
CTD |
PMID:22401849 |
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NCBI chr20:8,692,939...8,946,780
Ensembl chr20:8,692,963...8,946,772
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G |
Dnajb1 |
DnaJ heat shock protein family (Hsp40) member B1 |
increases expression |
ISO |
mono-(2-ethylhexyl)phthalate results in increased expression of DNAJB1 mRNA |
CTD |
PMID:24356939 |
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NCBI chr19:24,522,717...24,526,458
Ensembl chr19:24,522,717...24,526,458
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G |
Dnmt1 |
DNA methyltransferase 1 |
increases expression |
ISO |
mono-(2-ethylhexyl)phthalate results in increased expression of DNMT1 mRNA |
CTD |
PMID:22401849 |
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NCBI chr 8:19,440,611...19,486,659
Ensembl chr 8:19,440,611...19,486,659
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G |
Dock10 |
dedicator of cytokinesis 10 |
increases expression |
ISO |
mono-(2-ethylhexyl)phthalate results in increased expression of DOCK10 mRNA |
CTD |
PMID:22401849 |
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NCBI chr 9:81,843,599...82,101,540
Ensembl chr 9:81,843,604...82,101,525
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G |
Dock5 |
dedicator of cytokinesis 5 |
decreases expression |
ISO |
mono-(2-ethylhexyl)phthalate results in decreased expression of DOCK5 mRNA |
CTD |
PMID:22401849 |
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NCBI chr15:41,979,728...42,158,733
Ensembl chr15:41,979,729...42,158,649
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G |
Dpep1 |
dipeptidase 1 |
decreases expression |
ISO |
mono-(2-ethylhexyl)phthalate results in decreased expression of DPEP1 mRNA |
CTD |
PMID:22401849 |
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NCBI chr19:51,209,831...51,237,004
Ensembl chr19:51,219,660...51,235,257
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G |
Dpep2 |
dipeptidase 2 |
decreases expression |
ISO |
mono-(2-ethylhexyl)phthalate results in decreased expression of DPEP2 mRNA |
CTD |
PMID:22401849 |
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NCBI chr19:33,883,557...33,896,487
Ensembl chr19:33,885,478...33,891,954
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G |
Dpp6 |
dipeptidyl peptidase like 6 |
increases expression |
ISO |
mono-(2-ethylhexyl)phthalate results in increased expression of DPP6 mRNA |
CTD |
PMID:22401849 |
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NCBI chr 4:7,589,386...8,508,666
Ensembl chr 4:7,591,009...8,508,532
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G |
Dpy19l1 |
dpy-19 like C-mannosyltransferase 1 |
decreases expression |
ISO |
mono-(2-ethylhexyl)phthalate results in decreased expression of DPY19L1 mRNA |
CTD |
PMID:22401849 |
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NCBI chr 8:22,933,163...23,021,461
Ensembl chr 8:22,933,163...23,021,751
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G |
Dpysl4 |
dihydropyrimidinase-like 4 |
decreases expression |
ISO |
mono-(2-ethylhexyl)phthalate results in decreased expression of DPYSL4 mRNA |
CTD |
PMID:22401849 |
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NCBI chr 1:193,883,039...193,898,916
Ensembl chr 1:193,883,106...193,898,914
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G |
Dsc2 |
desmocollin 2 |
decreases expression |
ISO |
mono-(2-ethylhexyl)phthalate results in decreased expression of DSC2 mRNA |
CTD |
PMID:22401849 |
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NCBI chr18:11,450,392...11,482,476
Ensembl chr18:11,450,390...11,482,392
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G |
Dst |
dystonin |
increases expression |
ISO |
mono-(2-ethylhexyl)phthalate results in increased expression of DST mRNA |
CTD |
PMID:22401849 |
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NCBI chr 9:36,135,657...36,529,617
Ensembl chr 9:36,135,284...36,529,615
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G |
Dusp1 |
dual specificity phosphatase 1 |
increases expression decreases expression |
EXP ISO |
mono-(2-ethylhexyl)phthalate results in increased expression of DUSP1 mRNA mono-(2-ethylhexyl)phthalate results in decreased expression of DUSP1 mRNA |
CTD |
PMID:16809437 PMID:22401849 |
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NCBI chr10:16,680,489...16,683,276
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G |
Dusp5 |
dual specificity phosphatase 5 |
increases expression |
EXP |
mono-(2-ethylhexyl)phthalate results in increased expression of DUSP5 mRNA |
CTD |
PMID:16809437 |
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NCBI chr 1:252,538,408...252,555,320
Ensembl chr 1:252,538,449...252,551,818
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G |
Dusp6 |
dual specificity phosphatase 6 |
increases expression |
EXP |
mono-(2-ethylhexyl)phthalate results in increased expression of DUSP6 mRNA |
CTD |
PMID:16809437 |
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NCBI chr 7:34,092,848...34,097,186
Ensembl chr 7:34,092,943...34,097,185
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G |
Ebf3 |
EBF transcription factor 3 |
decreases expression |
ISO |
mono-(2-ethylhexyl)phthalate results in decreased expression of EBF3 mRNA |
CTD |
PMID:22401849 |
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NCBI chr 1:191,996,726...192,114,713
Ensembl chr 1:191,996,730...192,114,359
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G |
Ebp |
EBP, cholestenol delta-isomerase |
increases expression |
EXP |
mono-(2-ethylhexyl)phthalate results in increased expression of EBP mRNA |
CTD |
PMID:22087261 |
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NCBI chr X:14,299,427...14,305,826
Ensembl chr X:14,299,448...14,305,826
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G |
Ech1 |
enoyl-CoA hydratase 1 |
increases expression |
ISO |
mono-(2-ethylhexyl)phthalate results in increased expression of ECH1 mRNA |
CTD |
PMID:32522588 |
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NCBI chr 1:84,114,494...84,120,788
Ensembl chr 1:84,112,751...84,120,795
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G |
Eci1 |
enoyl-CoA delta isomerase 1 |
increases expression |
ISO |
mono-(2-ethylhexyl)phthalate results in increased expression of ECI1 mRNA |
CTD |
PMID:32522588 |
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NCBI chr10:13,456,715...13,470,061
Ensembl chr10:13,456,563...13,470,061
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G |
Ecm1 |
extracellular matrix protein 1 |
decreases expression |
ISO |
mono-(2-ethylhexyl)phthalate results in decreased expression of ECM1 mRNA |
CTD |
PMID:22401849 |
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NCBI chr 2:183,287,491...183,292,729
Ensembl chr 2:183,287,322...183,292,671
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G |
Edn1 |
endothelin 1 |
increases expression |
EXP |
mono-(2-ethylhexyl)phthalate results in increased expression of EDN1 mRNA |
CTD |
PMID:16809437 |
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NCBI chr17:22,454,924...22,460,812
Ensembl chr17:22,454,420...22,460,885
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G |
Efcab10 |
EF-hand calcium binding domain 10 |
affects expression |
ISO |
mono-(2-ethylhexyl)phthalate affects the expression of EFCAB10 mRNA |
CTD |
PMID:21195148 |
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NCBI chr 6:50,004,479...50,011,398
Ensembl chr 6:50,004,479...50,011,398
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G |
Efhd1 |
EF-hand domain family, member D1 |
decreases expression |
ISO |
mono-(2-ethylhexyl)phthalate results in decreased expression of EFHD1 mRNA |
CTD |
PMID:22401849 |
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NCBI chr 9:87,938,259...87,984,917
Ensembl chr 9:87,938,284...87,984,917
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G |
Efnb2 |
ephrin B2 |
increases expression |
EXP |
mono-(2-ethylhexyl)phthalate results in increased expression of EFNB2 mRNA |
CTD |
PMID:16809437 |
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NCBI chr16:80,783,389...80,827,420
Ensembl chr16:80,783,417...80,824,391
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G |
Egf |
epidermal growth factor |
decreases expression |
ISO |
mono-(2-ethylhexyl)phthalate results in decreased expression of EGF mRNA |
CTD |
PMID:22401849 |
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NCBI chr 2:218,219,408...218,302,370
Ensembl chr 2:218,219,415...218,302,064
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G |
Egr1 |
early growth response 1 |
increases expression |
EXP ISO |
mono-(2-ethylhexyl)phthalate results in increased expression of EGR1 mRNA |
CTD |
PMID:8764118 PMID:16809437 |
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NCBI chr18:26,463,333...26,465,531
Ensembl chr18:26,462,981...26,466,766
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G |
Egr3 |
early growth response 3 |
increases expression |
EXP |
mono-(2-ethylhexyl)phthalate results in increased expression of EGR3 mRNA |
CTD |
PMID:16809437 |
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NCBI chr15:45,150,335...45,156,052
Ensembl chr15:45,150,567...45,154,627
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G |
Egr4 |
early growth response 4 |
increases expression |
EXP |
mono-(2-ethylhexyl)phthalate results in increased expression of EGR4 mRNA |
CTD |
PMID:16809437 |
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NCBI chr 4:118,047,869...118,050,328
Ensembl chr 4:118,047,869...118,050,328
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G |
Eif5b |
eukaryotic translation initiation factor 5B |
increases expression |
ISO |
mono-(2-ethylhexyl)phthalate results in increased expression of EIF5B mRNA |
CTD |
PMID:22401849 |
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NCBI chr 9:40,222,769...40,277,482
Ensembl chr 9:40,222,898...40,277,482
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G |
Elf1 |
E74 like ETS transcription factor 1 |
increases expression |
EXP |
mono-(2-ethylhexyl)phthalate results in increased expression of ELF1 mRNA |
CTD |
PMID:16809437 |
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NCBI chr15:54,890,644...54,986,721
Ensembl chr15:54,865,616...54,986,699
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G |
Enox1 |
ecto-NOX disulfide-thiol exchanger 1 |
decreases expression |
ISO |
mono-(2-ethylhexyl)phthalate results in decreased expression of ENOX1 mRNA |
CTD |
PMID:22401849 |
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NCBI chr15:52,517,833...53,079,752
Ensembl chr15:52,515,178...53,079,749
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G |
Ep300 |
E1A binding protein p300 |
multiple interactions |
ISO |
mono-(2-ethylhexyl)phthalate promotes the reaction [PPARA protein binds to EP300 protein] |
CTD |
PMID:20123618 |
|
NCBI chr 7:113,108,476...113,178,529
Ensembl chr 7:113,106,247...113,136,088 Ensembl chr 7:113,106,247...113,136,088
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G |
Epb41l1 |
erythrocyte membrane protein band 4.1-like 1 |
affects expression |
ISO |
mono-(2-ethylhexyl)phthalate affects the expression of EPB41L1 mRNA |
CTD |
PMID:21195148 |
|
NCBI chr 3:144,929,195...145,052,723
Ensembl chr 3:144,984,640...145,052,721
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G |
Epb41l3 |
erythrocyte membrane protein band 4.1-like 3 |
affects expression |
ISO |
mono-(2-ethylhexyl)phthalate affects the expression of EPB41L3 mRNA |
CTD |
PMID:21195148 |
|
NCBI chr 9:109,056,178...109,260,607
Ensembl chr 9:109,016,113...109,260,607
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G |
Epdr1 |
ependymin related 1 |
decreases expression |
ISO |
mono-(2-ethylhexyl)phthalate results in decreased expression of EPDR1 mRNA |
CTD |
PMID:22401849 |
|
NCBI chr17:45,333,677...45,358,597
Ensembl chr17:45,333,956...45,358,594
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G |
Ephx1 |
epoxide hydrolase 1 |
increases expression |
EXP |
mono-(2-ethylhexyl)phthalate results in increased expression of EPHX1 mRNA |
CTD |
PMID:12706301 |
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NCBI chr13:92,714,315...92,744,124
Ensembl chr13:92,714,315...92,790,235
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G |
Ephx2 |
epoxide hydrolase 2 |
decreases expression |
ISO |
mono-(2-ethylhexyl)phthalate results in decreased expression of EPHX2 mRNA |
CTD |
PMID:22401849 |
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NCBI chr15:40,289,901...40,327,632
Ensembl chr15:40,289,902...40,327,615
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G |
Erbb4 |
erb-b2 receptor tyrosine kinase 4 |
increases expression |
ISO |
mono-(2-ethylhexyl)phthalate results in increased expression of ERBB4 mRNA |
CTD |
PMID:22401849 |
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NCBI chr 9:69,523,733...70,596,743
Ensembl chr 9:69,531,481...70,596,595
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G |
Ern2 |
endoplasmic reticulum to nucleus signaling 2 |
multiple interactions |
ISO |
mono-(2-ethylhexyl)phthalate promotes the reaction [INS protein results in increased phosphorylation of ERN2 protein] |
CTD |
PMID:31009676 |
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NCBI chr 1:176,726,454...176,743,289
Ensembl chr 1:176,726,454...176,743,289
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G |
Esr1 |
estrogen receptor 1 |
multiple interactions increases expression affects expression |
ISO |
[monoethyl phthalate co-treated with mono-(2-ethylhexyl)phthalate co-treated with mono-isobutyl phthalate co-treated with monoisononylphthalate co-treated with mono-benzyl phthalate] results in decreased expression of ESR1 mRNA; mono-(2-ethylhexyl)phthalate binds to and results in increased activity of ESR1 protein ESR1 protein affects the reaction [mono-(2-ethylhexyl)phthalate affects the expression of ESR1 mRNA]; ESR1 protein affects the reaction [mono-(2-ethylhexyl)phthalate affects the expression of MMP2 mRNA]; ESR1 protein affects the reaction [mono-(2-ethylhexyl)phthalate affects the expression of MMP9 mRNA]; ESR1 protein affects the reaction [mono-(2-ethylhexyl)phthalate affects the expression of TIMP2 mRNA]; ESR1 protein affects the reaction [mono-(2-ethylhexyl)phthalate results in increased expression of PCNA mRNA]; mono-(2-ethylhexyl)phthalate binds to and results in increased activity of ESR1 protein mono-(2-ethylhexyl)phthalate results in increased expression of ESR1 protein |
CTD |
PMID:20209442 PMID:31884101 PMID:33049310 PMID:33631300 |
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NCBI chr 1:41,106,335...41,499,104
Ensembl chr 1:41,210,475...41,495,002
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G |
Esr2 |
estrogen receptor 2 |
multiple interactions |
ISO |
[monoethyl phthalate co-treated with mono-(2-ethylhexyl)phthalate co-treated with mono-isobutyl phthalate co-treated with monoisononylphthalate co-treated with mono-benzyl phthalate] results in decreased expression of ESR2 mRNA mono-(2-ethylhexyl)phthalate binds to and results in increased activity of ESR2 protein |
CTD |
PMID:31884101 PMID:33049310 |
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NCBI chr 6:94,858,438...94,909,630
Ensembl chr 6:94,809,547...94,908,919
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G |
F10 |
coagulation factor X |
decreases expression |
ISO |
mono-(2-ethylhexyl)phthalate results in decreased expression of F10 mRNA |
CTD |
PMID:22401849 |
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NCBI chr16:76,468,834...76,488,141
Ensembl chr16:76,468,838...76,488,141
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G |
F3 |
coagulation factor III, tissue factor |
increases expression |
EXP |
mono-(2-ethylhexyl)phthalate results in increased expression of F3 mRNA |
CTD |
PMID:16809437 |
|
NCBI chr 2:209,827,061...209,838,666
Ensembl chr 2:209,826,959...209,838,668
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G |
Fabp3 |
fatty acid binding protein 3 |
increases expression |
EXP |
mono-(2-ethylhexyl)phthalate results in increased expression of FABP3 mRNA; mono-(2-ethylhexyl)phthalate results in increased expression of FABP3 protein |
CTD |
PMID:12706301 PMID:15647598 |
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NCBI chr 5:142,651,962...142,658,707
Ensembl chr 5:142,651,956...142,658,718
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G |
Fabp4 |
fatty acid binding protein 4 |
increases expression multiple interactions |
ISO |
mono-(2-ethylhexyl)phthalate analog results in increased expression of FABP4 mRNA; mono-(2-ethylhexyl)phthalate results in increased expression of FABP4 mRNA; mono-(2-ethylhexyl)phthalate results in increased expression of FABP4 protein T 0070907 inhibits the reaction [mono-(2-ethylhexyl)phthalate results in increased expression of FABP4 mRNA] |
CTD |
PMID:25543134 PMID:25777084 PMID:27384973 PMID:35421560 |
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NCBI chr 2:91,580,858...91,585,578
Ensembl chr 2:91,580,885...91,585,578
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G |
Fads6 |
fatty acid desaturase 6 |
decreases expression |
ISO |
mono-(2-ethylhexyl)phthalate results in decreased expression of FADS6 mRNA |
CTD |
PMID:22401849 |
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NCBI chr10:100,522,981...100,538,181
Ensembl chr10:100,522,981...100,538,181
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G |
Faim2 |
Fas apoptotic inhibitory molecule 2 |
decreases expression |
ISO |
mono-(2-ethylhexyl)phthalate results in decreased expression of FAIM2 mRNA |
CTD |
PMID:22401849 |
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NCBI chr 7:130,632,368...130,659,353
Ensembl chr 7:130,633,348...130,659,168
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G |
Far1 |
fatty acyl CoA reductase 1 |
decreases expression |
ISO |
mono-(2-ethylhexyl)phthalate results in decreased expression of FAR1 mRNA |
CTD |
PMID:22401849 |
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NCBI chr 1:167,644,622...167,705,868
Ensembl chr 1:167,644,677...167,705,730
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G |
Faslg |
Fas ligand |
affects response to substance multiple interactions |
ISO |
FASL affects the susceptibility to mono-(2-ethylhexyl)phthalate [FASL affects the susceptibility to mono-(2-ethylhexyl)phthalate] which affects the expression of CFLAR protein |
CTD |
PMID:20100735 |
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NCBI chr13:74,151,519...74,172,760
Ensembl chr13:74,154,954...74,162,215
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G |
Fasn |
fatty acid synthase |
increases expression multiple interactions decreases expression |
ISO |
mono-(2-ethylhexyl)phthalate results in increased expression of FASN mRNA mono-(2-ethylhexyl)phthalate results in increased expression of FASN protein [Genistein co-treated with mono-(2-ethylhexyl)phthalate] results in increased expression of FASN mRNA mono-(2-ethylhexyl)phthalate results in decreased expression of FASN mRNA |
CTD |
PMID:23118965 PMID:25543134 PMID:27181934 PMID:27384973 |
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NCBI chr10:106,072,093...106,090,259
Ensembl chr10:106,072,091...106,090,261
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G |
Fat1 |
FAT atypical cadherin 1 |
decreases expression |
EXP |
mono-(2-ethylhexyl)phthalate results in decreased expression of FAT1 mRNA |
CTD |
PMID:22087261 |
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NCBI chr16:47,177,253...47,296,261
Ensembl chr16:47,177,248...47,296,107
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G |
Fbln2 |
fibulin 2 |
decreases expression |
ISO |
mono-(2-ethylhexyl)phthalate results in decreased expression of FBLN2 mRNA |
CTD |
PMID:22401849 |
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NCBI chr 4:123,704,289...123,763,857
Ensembl chr 4:123,704,373...123,763,948
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G |
Fbxl22 |
F-box and leucine-rich repeat protein 22 |
decreases expression |
ISO |
mono-(2-ethylhexyl)phthalate results in decreased expression of FBXL22 mRNA |
CTD |
PMID:22401849 |
|
NCBI chr 8:67,069,998...67,076,685
Ensembl chr 8:67,069,998...67,076,685
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G |
Fcgbp |
Fc gamma binding protein |
increases expression |
ISO |
mono-(2-ethylhexyl)phthalate results in increased expression of FCGBP mRNA |
CTD |
PMID:22401849 |
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NCBI chr 1:83,374,979...83,413,083
Ensembl chr 1:83,372,127...83,413,083
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G |
Fdps |
farnesyl diphosphate synthase |
decreases expression |
ISO EXP |
mono-(2-ethylhexyl)phthalate results in decreased expression of FDPS mRNA |
CTD |
PMID:22087261 PMID:22401849 |
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NCBI chr 2:174,497,402...174,507,031
Ensembl chr 2:174,486,665...174,507,776
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G |
Fdx1 |
ferredoxin 1 |
decreases expression |
ISO EXP |
mono-(2-ethylhexyl)phthalate results in decreased expression of FDX1 mRNA |
CTD |
PMID:22087261 PMID:22401849 |
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NCBI chr 8:52,268,536...52,287,344
Ensembl chr 8:52,268,536...52,287,414
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G |
Fdxr |
ferredoxin reductase |
decreases expression |
ISO |
mono-(2-ethylhexyl)phthalate results in decreased expression of FDXR mRNA |
CTD |
PMID:22401849 |
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NCBI chr10:100,507,863...100,516,649
Ensembl chr10:100,507,865...100,516,658
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G |
Fer1l5 |
fer-1-like family member 5 |
decreases expression |
ISO |
mono-(2-ethylhexyl)phthalate results in decreased expression of FER1L5 mRNA |
CTD |
PMID:22401849 |
|
NCBI chr 9:38,605,835...38,661,869
Ensembl chr 9:38,607,843...38,660,425
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G |
Fgf21 |
fibroblast growth factor 21 |
increases expression increases secretion multiple interactions |
ISO |
mono-(2-ethylhexyl)phthalate results in increased expression of FGF21 mRNA mono-(2-ethylhexyl)phthalate results in increased secretion of FGF21 protein alpha-cyano-4-hydroxycinnamate inhibits the reaction [mono-(2-ethylhexyl)phthalate results in increased expression of FGF21 mRNA]; PPARA gene mutant form inhibits the reaction [mono-(2-ethylhexyl)phthalate results in increased expression of FGF21 mRNA]; PPARA inhibits the reaction [PPARA gene mutant form inhibits the reaction [mono-(2-ethylhexyl)phthalate results in increased expression of FGF21 mRNA]] |
CTD |
PMID:20123618 PMID:31009676 PMID:32522588 |
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NCBI chr 1:96,083,495...96,084,738
Ensembl chr 1:96,083,441...96,090,454
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G |
Fgf8 |
fibroblast growth factor 8 |
decreases expression |
ISO |
mono-(2-ethylhexyl)phthalate results in decreased expression of FGF8 mRNA |
CTD |
PMID:31711903 |
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NCBI chr 1:244,584,477...244,590,359
Ensembl chr 1:244,584,652...244,590,359
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G |
Fgfr3 |
fibroblast growth factor receptor 3 |
increases expression |
ISO |
mono-(2-ethylhexyl)phthalate results in increased expression of FGFR3 mRNA |
CTD |
PMID:31009676 |
|
NCBI chr14:76,987,242...77,002,671
Ensembl chr14:76,987,993...77,003,341
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G |
Fgfr4 |
fibroblast growth factor receptor 4 |
increases expression |
ISO |
mono-(2-ethylhexyl)phthalate results in increased expression of FGFR4 mRNA |
CTD |
PMID:31009676 |
|
NCBI chr17:9,461,541...9,476,268
Ensembl chr17:9,461,547...9,476,242
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G |
Fibin |
fin bud initiation factor homolog |
increases expression |
EXP |
mono-(2-ethylhexyl)phthalate results in increased expression of FIBIN mRNA |
CTD |
PMID:16809437 |
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NCBI chr 3:96,942,405...96,944,676
Ensembl chr 3:96,942,406...96,944,676
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G |
Fkbp1a |
FKBP prolyl isomerase 1A |
decreases expression |
ISO |
mono-(2-ethylhexyl)phthalate results in decreased expression of FKBP1A mRNA |
CTD |
PMID:22401849 |
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NCBI chr 3:140,040,359...140,060,107
Ensembl chr 3:140,040,278...140,060,743
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G |
Fkbp5 |
FKBP prolyl isomerase 5 |
decreases expression |
ISO |
mono-(2-ethylhexyl)phthalate results in decreased expression of FKBP5 mRNA |
CTD |
PMID:22401849 |
|
NCBI chr20:6,457,207...6,575,404
Ensembl chr20:6,457,216...6,541,674
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G |
Flg |
filaggrin |
multiple interactions |
ISO |
[FLG gene polymorphism affects the susceptibility to Diethylhexyl Phthalate] which affects the abundance of mono-(2-ethylhexyl)phthalate |
CTD |
PMID:24380925 |
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NCBI chr 2:178,888,688...178,912,731
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G |
Fmnl3 |
formin-like 3 |
decreases expression |
ISO |
mono-(2-ethylhexyl)phthalate results in decreased expression of FMNL3 mRNA |
CTD |
PMID:22401849 |
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NCBI chr 7:130,454,270...130,505,621
Ensembl chr 7:130,454,275...130,505,626
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G |
Fmo2 |
flavin containing dimethylaniline monoxygenase 2 |
increases expression |
EXP |
mono-(2-ethylhexyl)phthalate results in increased expression of FMO2 mRNA |
CTD |
PMID:16809437 |
|
NCBI chr13:75,221,149...75,244,377
Ensembl chr13:75,224,402...75,244,308
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G |
Fmo3 |
flavin containing dimethylaniline monoxygenase 3 |
increases expression |
EXP |
mono-(2-ethylhexyl)phthalate results in increased expression of FMO3 mRNA |
CTD |
PMID:16809437 |
|
NCBI chr13:75,309,367...75,334,915
Ensembl chr13:75,309,374...75,328,028
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G |
Folr1 |
folate receptor alpha |
affects expression |
ISO |
mono-(2-ethylhexyl)phthalate affects the expression of FOLR1 mRNA |
CTD |
PMID:27167697 |
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NCBI chr 1:156,219,460...156,238,436
Ensembl chr 1:156,219,460...156,230,667
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G |
Fos |
Fos proto-oncogene, AP-1 transcription factor subunit |
increases expression multiple interactions |
EXP ISO |
mono-(2-ethylhexyl)phthalate results in increased expression of FOS mRNA mono-(2-ethylhexyl)phthalate inhibits the reaction [GDNF protein results in increased expression of FOS mRNA]; mono-(2-ethylhexyl)phthalate inhibits the reaction [GDNF protein results in increased expression of FOS protein] |
CTD |
PMID:8764118 PMID:16809437 PMID:22564763 |
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NCBI chr 6:105,121,170...105,124,036
Ensembl chr 6:105,121,170...105,124,036
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G |
Foxa1 |
forkhead box A1 |
affects expression |
ISO |
mono-(2-ethylhexyl)phthalate affects the expression of FOXA1 mRNA |
CTD |
PMID:21195148 |
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NCBI chr 6:75,099,907...75,136,534
Ensembl chr 6:75,103,503...75,136,188
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G |
Foxd4 |
forkhead box D4 |
affects expression |
ISO |
mono-(2-ethylhexyl)phthalate affects the expression of FOXD4 mRNA |
CTD |
PMID:21195148 |
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NCBI chr 1:222,557,494...222,559,189
Ensembl chr 1:222,557,360...222,559,159
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G |
Foxj1 |
forkhead box J1 |
affects expression |
ISO |
mono-(2-ethylhexyl)phthalate affects the expression of FOXJ1 mRNA |
CTD |
PMID:21195148 |
|
NCBI chr10:101,566,299...101,570,249
Ensembl chr10:101,566,304...101,570,237
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G |
Foxl2 |
forkhead box L2 |
multiple interactions |
EXP |
mono-(2-ethylhexyl)phthalate inhibits the reaction [Tretinoin results in increased expression of FOXL2 mRNA] |
CTD |
PMID:30476341 |
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NCBI chr 8:99,512,971...99,514,500
Ensembl chr 8:99,513,303...99,514,427
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G |
Foxo1 |
forkhead box O1 |
decreases phosphorylation multiple interactions decreases expression |
ISO EXP |
mono-(2-ethylhexyl)phthalate results in decreased phosphorylation of FOXO1 protein Genistein inhibits the reaction [mono-(2-ethylhexyl)phthalate results in decreased expression of FOXO1 mRNA] [mono-(2-ethylhexyl)phthalate co-treated with Genistein] results in increased expression of FOXO1 mRNA |
CTD |
PMID:31228551 PMID:34942354 |
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NCBI chr 2:136,312,168...136,390,603
Ensembl chr 2:136,312,168...136,387,790
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G |
Frmd5 |
FERM domain containing 5 |
decreases expression |
ISO |
mono-(2-ethylhexyl)phthalate results in decreased expression of FRMD5 mRNA |
CTD |
PMID:22401849 |
|
NCBI chr 3:108,492,099...108,763,715
Ensembl chr 3:108,474,562...108,763,498
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G |
Fshb |
follicle stimulating hormone subunit beta |
multiple interactions increases expression decreases expression |
ISO |
mono-(2-ethylhexyl)phthalate inhibits the reaction [FSHB protein results in increased abundance of Estradiol] mono-(2-ethylhexyl)phthalate results in increased expression of FSHB protein mono-(2-ethylhexyl)phthalate results in decreased expression of FSHB mRNA |
CTD |
PMID:19501113 PMID:22401849 PMID:34954075 |
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NCBI chr 3:93,548,560...93,552,370
Ensembl chr 3:93,548,560...93,552,370
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G |
Fshr |
follicle stimulating hormone receptor |
decreases expression multiple interactions |
ISO |
mono-(2-ethylhexyl)phthalate results in decreased expression of FSHR mRNA [monoethyl phthalate co-treated with mono-(2-ethylhexyl)phthalate co-treated with mono-isobutyl phthalate co-treated with monoisononylphthalate co-treated with mono-benzyl phthalate] results in decreased expression of FSHR mRNA |
CTD |
PMID:22401849 PMID:31884101 |
|
NCBI chr 6:5,198,825...5,406,785
Ensembl chr 6:5,198,825...5,406,785
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G |
G6pc1 |
glucose-6-phosphatase catalytic subunit 1 |
increases expression |
ISO |
mono-(2-ethylhexyl)phthalate results in increased expression of G6PC1 protein |
CTD |
PMID:31228551 |
|
NCBI chr10:86,307,400...86,318,766
Ensembl chr10:86,257,668...86,333,804
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G |
Gabbr2 |
gamma-aminobutyric acid type B receptor subunit 2 |
increases expression |
ISO |
mono-(2-ethylhexyl)phthalate results in increased expression of GABBR2 mRNA |
CTD |
PMID:22401849 |
|
NCBI chr 5:60,947,517...61,288,104
Ensembl chr 5:60,947,526...61,288,104
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G |
Galnt13 |
polypeptide N-acetylgalactosaminyltransferase 13 |
decreases expression |
ISO |
mono-(2-ethylhexyl)phthalate results in decreased expression of GALNT13 mRNA |
CTD |
PMID:22401849 |
|
NCBI chr 3:38,903,695...39,560,683
Ensembl chr 3:38,974,490...39,558,803
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G |
Galnt7 |
polypeptide N-acetylgalactosaminyltransferase 7 |
decreases expression |
ISO |
mono-(2-ethylhexyl)phthalate results in decreased expression of GALNT7 mRNA |
CTD |
PMID:22401849 |
|
NCBI chr16:32,578,643...32,703,189
Ensembl chr16:32,578,690...32,702,690
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G |
Gamt |
guanidinoacetate N-methyltransferase |
decreases expression |
ISO |
mono-(2-ethylhexyl)phthalate results in decreased expression of GAMT mRNA |
CTD |
PMID:22401849 |
|
NCBI chr 7:9,448,590...9,451,778
Ensembl chr 7:9,448,628...9,451,778
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G |
Gapdh |
glyceraldehyde-3-phosphate dehydrogenase |
increases expression |
ISO |
mono-(2-ethylhexyl)phthalate results in increased expression of GAPDH protein |
CTD |
PMID:25543134 PMID:27384973 |
|
NCBI chr 4:157,962,312...157,967,158
Ensembl chr 4:157,962,343...157,966,235
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G |
Gask1b |
golgi associated kinase 1B |
decreases expression |
ISO |
mono-(2-ethylhexyl)phthalate results in decreased expression of GASK1B mRNA |
CTD |
PMID:22401849 |
|
NCBI chr 2:165,047,689...165,112,479
Ensembl chr 2:165,047,684...165,112,477
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G |
Gck |
glucokinase |
decreases expression |
ISO |
mono-(2-ethylhexyl)phthalate results in decreased expression of GCK protein |
CTD |
PMID:31228551 |
|
NCBI chr14:80,785,060...80,829,842
Ensembl chr14:80,785,060...80,826,995
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G |
Gdnf |
glial cell derived neurotrophic factor |
multiple interactions |
ISO |
mono-(2-ethylhexyl)phthalate inhibits the reaction [GDNF protein results in increased expression of FOS mRNA]; mono-(2-ethylhexyl)phthalate inhibits the reaction [GDNF protein results in increased expression of FOS protein]; mono-(2-ethylhexyl)phthalate inhibits the reaction [GDNF protein results in increased phosphorylation of MAPK1 protein]; mono-(2-ethylhexyl)phthalate inhibits the reaction [GDNF protein results in increased phosphorylation of MAPK3 protein] |
CTD |
PMID:22564763 |
|
NCBI chr 2:56,893,992...56,919,935
Ensembl chr 2:56,895,010...56,917,209
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G |
Gdpd4 |
glycerophosphodiester phosphodiesterase domain containing 4 |
increases expression |
ISO |
mono-(2-ethylhexyl)phthalate results in increased expression of GDPD4 mRNA |
CTD |
PMID:22401849 |
|
NCBI chr 1:152,233,516...152,342,329
Ensembl chr 1:152,233,499...152,342,158
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G |
Gga2 |
golgi associated, gamma adaptin ear containing, ARF binding protein 2 |
increases expression |
ISO |
mono-(2-ethylhexyl)phthalate results in increased expression of GGA2 mRNA |
CTD |
PMID:22401849 |
|
NCBI chr 1:176,552,046...176,585,332
Ensembl chr 1:176,552,046...176,585,361
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G |
Ggh |
gamma-glutamyl hydrolase |
decreases expression |
ISO |
mono-(2-ethylhexyl)phthalate results in decreased expression of GGH mRNA |
CTD |
PMID:22401849 |
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NCBI chr 5:33,529,880...33,552,790
Ensembl chr 5:33,529,880...33,552,787
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G |
Gja1 |
gap junction protein, alpha 1 |
decreases expression multiple interactions |
ISO EXP |
mono-(2-ethylhexyl)phthalate results in decreased expression of GJA1 mRNA [Ascorbic Acid co-treated with Vitamin E] inhibits the reaction [mono-(2-ethylhexyl)phthalate results in decreased expression of GJA1 protein] |
CTD |
PMID:22321834 PMID:29940330 |
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NCBI chr20:35,756,007...35,768,481
Ensembl chr20:35,755,991...35,768,582
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G |
Gli3 |
GLI family zinc finger 3 |
affects expression |
ISO |
mono-(2-ethylhexyl)phthalate affects the expression of GLI3 mRNA |
CTD |
PMID:26710974 |
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NCBI chr17:49,438,567...49,709,712
Ensembl chr17:49,438,567...49,709,712
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G |
Glrx2 |
glutaredoxin 2 |
increases expression |
ISO |
mono-(2-ethylhexyl)phthalate results in increased expression of GLRX2 mRNA |
CTD |
PMID:23360888 |
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NCBI chr13:55,481,875...55,504,737
Ensembl chr13:55,482,694...55,492,831
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G |
Gm2a |
ganglioside GM2 activator |
decreases expression |
ISO |
mono-(2-ethylhexyl)phthalate results in decreased expression of GM2A mRNA |
CTD |
PMID:22401849 |
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NCBI chr10:39,219,221...39,231,756
Ensembl chr10:39,219,243...39,231,757
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G |
Gnrhr |
gonadotropin releasing hormone receptor |
increases expression decreases expression |
EXP ISO |
mono-(2-ethylhexyl)phthalate results in increased expression of GNRHR mRNA mono-(2-ethylhexyl)phthalate results in decreased expression of GNRHR mRNA |
CTD |
PMID:16809437 PMID:34954075 |
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NCBI chr14:21,856,871...21,874,861
Ensembl chr14:21,856,871...21,874,861
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G |
Got2 |
glutamic-oxaloacetic transaminase 2 |
decreases expression |
EXP |
mono-(2-ethylhexyl)phthalate results in decreased expression of GOT2 mRNA |
CTD |
PMID:22087261 |
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NCBI chr19:9,174,304...9,199,995
Ensembl chr19:9,174,311...9,199,994
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G |
Gpd1 |
glycerol-3-phosphate dehydrogenase 1 |
increases expression |
ISO |
mono-(2-ethylhexyl)phthalate results in increased expression of GPD1 protein |
CTD |
PMID:27384973 |
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NCBI chr 7:130,842,526...130,851,530
Ensembl chr 7:130,844,138...130,851,529
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G |
Gpld1 |
glycosylphosphatidylinositol specific phospholipase D1 |
decreases expression |
ISO |
mono-(2-ethylhexyl)phthalate results in decreased expression of GPLD1 mRNA |
CTD |
PMID:22401849 |
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NCBI chr17:40,084,427...40,132,035
Ensembl chr17:40,084,617...40,126,939
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G |
Gpr141 |
G protein-coupled receptor 141 |
decreases expression |
ISO |
mono-(2-ethylhexyl)phthalate results in decreased expression of GPR141 mRNA |
CTD |
PMID:22401849 |
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NCBI chr17:45,177,056...45,199,267
Ensembl chr17:45,117,812...45,180,027
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G |
Gpx1 |
glutathione peroxidase 1 |
decreases activity multiple interactions decreases expression |
ISO EXP |
mono-(2-ethylhexyl)phthalate results in decreased activity of GPX1 protein [monoethyl phthalate co-treated with mono-(2-ethylhexyl)phthalate co-treated with mono-isobutyl phthalate co-treated with monoisononylphthalate co-treated with mono-benzyl phthalate] results in decreased expression of GPX1 mRNA; Selenomethionine inhibits the reaction [mono-(2-ethylhexyl)phthalate results in decreased activity of GPX1 protein]; Sodium Selenite inhibits the reaction [mono-(2-ethylhexyl)phthalate results in decreased activity of GPX1 protein] mono-(2-ethylhexyl)phthalate results in decreased expression of GPX1 mRNA |
CTD |
PMID:20659492 PMID:22087261 PMID:31884101 |
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NCBI chr 8:109,026,905...109,028,031
Ensembl chr 8:109,026,905...109,028,024
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G |
Gpx3 |
glutathione peroxidase 3 |
decreases expression |
ISO |
mono-(2-ethylhexyl)phthalate results in decreased expression of GPX3 mRNA |
CTD |
PMID:22401849 |
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NCBI chr10:39,028,624...39,036,695
Ensembl chr10:39,028,570...39,037,035
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G |
Grin3b |
glutamate ionotropic receptor NMDA type subunit 3B |
decreases expression |
ISO |
mono-(2-ethylhexyl)phthalate results in decreased expression of GRIN3B mRNA |
CTD |
PMID:22401849 |
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NCBI chr 7:9,730,861...9,737,183
Ensembl chr 7:9,730,862...9,737,183
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G |
Gsk3b |
glycogen synthase kinase 3 beta |
multiple interactions decreases phosphorylation |
EXP ISO |
mono-(2-ethylhexyl)phthalate inhibits the reaction [INS1 protein results in increased phosphorylation of GSK3B protein] mono-(2-ethylhexyl)phthalate results in decreased phosphorylation of GSK3B protein [mono-(2-ethylhexyl)phthalate results in decreased activity of INS protein] which results in decreased phosphorylation of GSK3B protein; RBP4 protein promotes the reaction [[mono-(2-ethylhexyl)phthalate results in decreased activity of INS protein] which results in decreased phosphorylation of GSK3B protein]; RBP4 protein promotes the reaction [mono-(2-ethylhexyl)phthalate results in decreased phosphorylation of GSK3B protein] |
CTD |
PMID:28526321 PMID:31228551 |
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NCBI chr11:62,498,997...62,648,665
Ensembl chr11:62,504,316...62,648,646
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G |
Gsr |
glutathione-disulfide reductase |
multiple interactions |
ISO |
[monoethyl phthalate co-treated with mono-(2-ethylhexyl)phthalate co-treated with mono-isobutyl phthalate co-treated with monoisononylphthalate co-treated with mono-benzyl phthalate] results in increased expression of GSR mRNA |
CTD |
PMID:31884101 |
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NCBI chr16:58,482,209...58,525,256
Ensembl chr16:58,482,505...58,525,661
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G |
Gsta4 |
glutathione S-transferase alpha 4 |
decreases expression |
EXP |
mono-(2-ethylhexyl)phthalate results in decreased expression of GSTA4 mRNA |
CTD |
PMID:22087261 |
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NCBI chr 8:79,066,967...79,084,193
Ensembl chr 8:79,066,934...79,084,182
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G |
Gstm1 |
glutathione S-transferase mu 1 |
increases expression |
ISO |
mono-(2-ethylhexyl)phthalate results in increased expression of GSTM1 protein |
CTD |
PMID:27384973 |
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NCBI chr 2:195,649,845...195,655,402
Ensembl chr 2:195,649,845...195,655,411
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G |
Gulp1 |
GULP PTB domain containing engulfment adaptor 1 |
decreases expression |
ISO |
mono-(2-ethylhexyl)phthalate results in decreased expression of GULP1 mRNA |
CTD |
PMID:22401849 |
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NCBI chr 9:46,622,699...46,899,005
Ensembl chr 9:46,622,669...46,899,005
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G |
Gys1 |
glycogen synthase 1 |
increases phosphorylation |
ISO |
mono-(2-ethylhexyl)phthalate results in increased phosphorylation of GYS1 protein |
CTD |
PMID:31228551 |
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NCBI chr 1:95,915,443...95,935,292
Ensembl chr 1:95,915,443...95,935,292
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G |
Hace1 |
HECT domain and ankyrin repeat containing, E3 ubiquitin protein ligase 1 |
decreases expression |
ISO |
mono-(2-ethylhexyl)phthalate results in decreased expression of HACE1 mRNA |
CTD |
PMID:22401849 |
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NCBI chr20:49,035,312...49,151,103
Ensembl chr20:49,035,648...49,151,103
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G |
Hadha |
hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit alpha |
increases expression |
ISO |
mono-(2-ethylhexyl)phthalate results in increased expression of HADHA mRNA |
CTD |
PMID:32522588 |
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NCBI chr 6:26,187,969...26,227,605
Ensembl chr 6:26,187,956...26,227,869
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G |
Has2 |
hyaluronan synthase 2 |
affects expression |
ISO |
mono-(2-ethylhexyl)phthalate affects the expression of HAS2 mRNA |
CTD |
PMID:21195148 |
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NCBI chr 7:88,113,326...88,139,337
Ensembl chr 7:88,113,326...88,128,933
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G |
Hccs |
holocytochrome c synthase |
decreases expression |
ISO |
mono-(2-ethylhexyl)phthalate results in decreased expression of HCCS mRNA |
CTD |
PMID:22401849 |
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NCBI chr X:24,932,943...24,942,376
Ensembl chr X:24,933,002...24,942,366
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G |
Hdac6 |
histone deacetylase 6 |
multiple interactions |
ISO |
[bisphenol A co-treated with mono-(2-ethylhexyl)phthalate] results in increased expression of HDAC6 protein; [mono-(2-ethylhexyl)phthalate co-treated with bisphenol A] inhibits the reaction [HDAC6 protein affects the phosphorylation of MAPK1 protein]; [mono-(2-ethylhexyl)phthalate co-treated with bisphenol A] inhibits the reaction [HDAC6 protein affects the phosphorylation of MAPK3 protein]; HDAC6 protein affects the reaction [[bisphenol A co-treated with mono-(2-ethylhexyl)phthalate] results in decreased expression of PTEN protein]; HDAC6 protein affects the reaction [[bisphenol A co-treated with mono-(2-ethylhexyl)phthalate] results in increased expression of MYC protein]; HDAC6 protein affects the reaction [[bisphenol A co-treated with mono-(2-ethylhexyl)phthalate] results in increased phosphorylation of AKT1 protein]; tubastatin A inhibits the reaction [[bisphenol A co-treated with mono-(2-ethylhexyl)phthalate] results in increased expression of HDAC6 protein] |
CTD |
PMID:34910997 |
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NCBI chr X:14,550,645...14,572,445
Ensembl chr X:14,551,044...14,572,441
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G |
Hecw2 |
HECT, C2 and WW domain containing E3 ubiquitin protein ligase 2 |
increases expression |
ISO |
mono-(2-ethylhexyl)phthalate results in increased expression of HECW2 mRNA |
CTD |
PMID:22401849 |
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NCBI chr 9:55,359,462...55,753,106
Ensembl chr 9:55,365,203...55,580,327
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G |
Hif1a |
hypoxia inducible factor 1 subunit alpha |
increases expression |
ISO |
mono-(2-ethylhexyl)phthalate results in increased expression of HIF1A protein |
CTD |
PMID:34627990 |
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NCBI chr 6:92,624,059...92,669,262
Ensembl chr 6:92,624,390...92,669,261
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G |
Hmgcr |
3-hydroxy-3-methylglutaryl-CoA reductase |
increases expression multiple interactions |
ISO |
mono-(2-ethylhexyl)phthalate results in increased expression of HMGCR mRNA [Genistein co-treated with mono-(2-ethylhexyl)phthalate] results in increased expression of HMGCR mRNA |
CTD |
PMID:23118965 PMID:27181934 |
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NCBI chr 2:27,997,523...28,018,983
Ensembl chr 2:27,997,525...28,019,703
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G |
Hmgcs1 |
3-hydroxy-3-methylglutaryl-CoA synthase 1 |
decreases expression increases expression |
ISO EXP |
mono-(2-ethylhexyl)phthalate results in decreased expression of HMGCS1 mRNA mono-(2-ethylhexyl)phthalate results in increased expression of HMGCS1 mRNA |
CTD |
PMID:22087261 PMID:22401849 |
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NCBI chr 2:51,649,368...51,667,100
Ensembl chr 2:51,649,497...51,667,100
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G |
Homer3 |
homer scaffold protein 3 |
decreases expression |
ISO |
mono-(2-ethylhexyl)phthalate results in decreased expression of HOMER3 mRNA |
CTD |
PMID:22401849 |
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NCBI chr16:19,132,177...19,142,739
Ensembl chr16:19,132,162...19,142,680
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G |
Hoxb7 |
homeo box B7 |
increases expression |
ISO |
mono-(2-ethylhexyl)phthalate results in increased expression of HOXB7 mRNA |
CTD |
PMID:31711903 |
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NCBI chr10:81,252,616...81,256,034
Ensembl chr10:81,252,553...81,256,034
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G |
Hoxb9 |
homeo box B9 |
increases expression |
ISO |
mono-(2-ethylhexyl)phthalate results in increased expression of HOXB9 mRNA |
CTD |
PMID:31711903 |
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NCBI chr10:81,237,312...81,240,818
Ensembl chr10:81,237,312...81,240,818
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G |
Hsd11b2 |
hydroxysteroid 11-beta dehydrogenase 2 |
decreases activity affects expression |
ISO EXP |
mono-(2-ethylhexyl)phthalate results in decreased activity of HSD11B2 protein mono-(2-ethylhexyl)phthalate affects the expression of HSD11B2 mRNA |
CTD |
PMID:19786001 PMID:21195148 |
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NCBI chr19:33,397,656...33,402,899
Ensembl chr19:33,397,656...33,402,899
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G |
Hsd17b1 |
hydroxysteroid (17-beta) dehydrogenase 1 |
multiple interactions |
ISO |
[monoethyl phthalate co-treated with mono-(2-ethylhexyl)phthalate co-treated with mono-isobutyl phthalate co-treated with monoisononylphthalate co-treated with mono-benzyl phthalate] results in decreased expression of HSD17B1 mRNA |
CTD |
PMID:31884101 |
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NCBI chr10:86,009,728...86,011,928
Ensembl chr10:86,009,728...86,011,927
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G |
Hsd17b4 |
hydroxysteroid (17-beta) dehydrogenase 4 |
increases expression |
EXP |
mono-(2-ethylhexyl)phthalate results in increased expression of HSD17B4 mRNA |
CTD |
PMID:12706301 |
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NCBI chr18:43,328,903...43,417,950
Ensembl chr18:43,328,824...43,417,952
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G |
Hsd3b1 |
hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1 |
multiple interactions |
ISO |
[monoethyl phthalate co-treated with mono-(2-ethylhexyl)phthalate co-treated with mono-isobutyl phthalate co-treated with monoisononylphthalate co-treated with mono-benzyl phthalate] results in decreased expression of HSD3B1 mRNA |
CTD |
PMID:31884101 |
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NCBI chr 2:186,169,864...186,175,984
Ensembl chr 2:186,169,863...186,175,999
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G |
Hsdl2 |
hydroxysteroid dehydrogenase like 2 |
increases expression |
ISO |
mono-(2-ethylhexyl)phthalate results in increased expression of HSDL2 mRNA |
CTD |
PMID:32522588 |
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NCBI chr 5:74,443,933...74,479,104
Ensembl chr 5:74,443,872...74,479,839
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G |
Hsp90aa1 |
heat shock protein 90 alpha family class A member 1 |
decreases expression |
EXP |
mono-(2-ethylhexyl)phthalate results in decreased expression of HSP90AA1 mRNA |
CTD |
PMID:22087261 |
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NCBI chr 6:129,702,376...129,707,907
Ensembl chr 6:129,702,383...129,707,268
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G |
Hspa1a |
heat shock protein family A (Hsp70) member 1A |
increases expression |
ISO |
mono-(2-ethylhexyl)phthalate results in increased expression of HSPA1B mRNA |
CTD |
PMID:24356939 |
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NCBI chr20:3,855,104...3,859,148
Ensembl chr20:3,856,006...3,873,240
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G |
Hycc1 |
hyccin PI4KA lipid kinase complex subunit 1 |
decreases expression |
ISO |
mono-(2-ethylhexyl)phthalate results in decreased expression of HYCC1 mRNA |
CTD |
PMID:22401849 |
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NCBI chr 4:11,132,224...11,239,120
Ensembl chr 4:11,132,385...11,239,113
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G |
Id1 |
inhibitor of DNA binding 1 |
decreases expression |
ISO |
mono-(2-ethylhexyl)phthalate results in decreased expression of ID1 mRNA |
CTD |
PMID:22321834 |
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NCBI chr 3:141,210,666...141,212,420
Ensembl chr 3:141,211,267...141,212,419
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G |
Idh1 |
isocitrate dehydrogenase (NADP(+)) 1 |
decreases expression |
ISO |
mono-(2-ethylhexyl)phthalate results in decreased expression of IDH1 mRNA |
CTD |
PMID:22401849 |
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NCBI chr 9:66,534,146...66,563,703
Ensembl chr 9:66,534,146...66,563,708
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G |
Ier3 |
immediate early response 3 |
increases expression |
EXP |
mono-(2-ethylhexyl)phthalate results in increased expression of IER3 mRNA |
CTD |
PMID:16809437 |
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NCBI chr20:2,928,378...2,929,582
Ensembl chr20:2,928,378...2,929,583
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G |
Ifng |
interferon gamma |
multiple interactions |
ISO |
mono-(2-ethylhexyl)phthalate inhibits the reaction [[Lipopolysaccharides co-treated with IFNG protein] results in increased expression of CD163 mRNA]; mono-(2-ethylhexyl)phthalate inhibits the reaction [[Lipopolysaccharides co-treated with IFNG protein] results in increased expression of CD36 mRNA]; mono-(2-ethylhexyl)phthalate inhibits the reaction [[Lipopolysaccharides co-treated with IFNG protein] results in increased expression of IL1B mRNA]; mono-(2-ethylhexyl)phthalate inhibits the reaction [[Lipopolysaccharides co-treated with IFNG protein] results in increased expression of MARCO mRNA]; mono-(2-ethylhexyl)phthalate inhibits the reaction [[Lipopolysaccharides co-treated with IFNG protein] results in increased expression of MMP9 mRNA]; mono-(2-ethylhexyl)phthalate inhibits the reaction [[Lipopolysaccharides co-treated with IFNG protein] results in increased expression of NOS2 mRNA]; mono-(2-ethylhexyl)phthalate promotes the reaction [[Lipopolysaccharides co-treated with IFNG protein] results in increased expression of IL6 mRNA]; mono-(2-ethylhexyl)phthalate promotes the reaction [[Lipopolysaccharides co-treated with IFNG protein] results in increased expression of TNF mRNA] |
CTD |
PMID:29718165 |
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NCBI chr 7:53,903,339...53,907,375
Ensembl chr 7:53,903,337...53,907,375
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G |
Igf2bp1 |
insulin-like growth factor 2 mRNA binding protein 1 |
decreases expression |
ISO |
mono-(2-ethylhexyl)phthalate results in decreased expression of IGF2BP1 mRNA |
CTD |
PMID:22401849 |
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NCBI chr10:80,908,300...80,951,097
Ensembl chr10:80,908,076...80,951,129
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G |
Ikbkg |
inhibitor of nuclear factor kappa B kinase regulatory subunit gamma |
decreases expression |
ISO |
mono-(2-ethylhexyl)phthalate results in decreased expression of IKBKG mRNA |
CTD |
PMID:22401849 |
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NCBI chr X:152,216,485...152,241,476
Ensembl chr X:152,216,596...152,239,499
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G |
Il16 |
interleukin 16 |
decreases expression |
ISO |
mono-(2-ethylhexyl)phthalate results in decreased expression of IL16 mRNA |
CTD |
PMID:22401849 |
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NCBI chr 1:137,617,702...137,718,022
Ensembl chr 1:137,617,944...137,718,130
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G |
Il17rd |
interleukin 17 receptor D |
decreases expression |
ISO |
mono-(2-ethylhexyl)phthalate results in decreased expression of IL17RD mRNA |
CTD |
PMID:22321834 |
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NCBI chr16:2,228,467...2,295,126
Ensembl chr16:2,228,287...2,292,556
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G |
Il1a |
interleukin 1 alpha |
increases expression |
EXP |
mono-(2-ethylhexyl)phthalate results in increased expression of IL1A mRNA |
CTD |
PMID:16809437 |
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NCBI chr 3:116,526,601...116,537,055
Ensembl chr 3:116,526,604...116,536,822
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G |
Il1b |
interleukin 1 beta |
multiple interactions increases expression increases secretion |
ISO |
mono-(2-ethylhexyl)phthalate inhibits the reaction [[Lipopolysaccharides co-treated with IFNG protein] results in increased expression of IL1B mRNA] mono-(2-ethylhexyl)phthalate results in increased expression of IL1B mRNA mono-(2-ethylhexyl)phthalate results in increased secretion of IL1B protein |
CTD |
PMID:29718165 PMID:31016965 |
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NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415
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G |
Il27ra |
interleukin 27 receptor subunit alpha |
decreases expression |
ISO |
mono-(2-ethylhexyl)phthalate results in decreased expression of IL27RA mRNA |
CTD |
PMID:22401849 |
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NCBI chr19:24,109,698...24,121,977
Ensembl chr19:24,109,972...24,121,938
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G |
Il6 |
interleukin 6 |
increases expression multiple interactions |
ISO |
mono-(2-ethylhexyl)phthalate results in increased expression of IL6 mRNA [bisphenol A co-treated with mono-(2-ethylhexyl)phthalate co-treated with mono-benzyl phthalate co-treated with monobutyl phthalate] results in increased expression of IL6 mRNA mono-(2-ethylhexyl)phthalate promotes the reaction [[Lipopolysaccharides co-treated with IFNG protein] results in increased expression of IL6 mRNA] |
CTD |
PMID:27384973 PMID:29718165 PMID:30398665 |
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NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178
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G |
Inha |
inhibin subunit alpha |
decreases expression |
EXP |
mono-(2-ethylhexyl)phthalate results in decreased expression of INHA mRNA |
CTD |
PMID:22087261 |
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NCBI chr 9:76,994,465...76,997,366
Ensembl chr 9:76,993,589...76,997,248
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G |
Ins1 |
insulin 1 |
multiple interactions increases expression |
EXP ISO |
[INS1 protein co-treated with mono-(2-ethylhexyl)phthalate] results in decreased expression of and results in decreased phosphorylation of INSR protein; [INS1 protein co-treated with mono-(2-ethylhexyl)phthalate] results in decreased expression of IRS1 protein; [INS1 protein co-treated with mono-(2-ethylhexyl)phthalate] results in decreased expression of RAB13 protein; [INS1 protein co-treated with mono-(2-ethylhexyl)phthalate] results in decreased expression of RAB8A protein; [INS1 protein co-treated with mono-(2-ethylhexyl)phthalate] results in decreased expression of SLC2A4 protein; [INS1 protein co-treated with mono-(2-ethylhexyl)phthalate] results in decreased expression of SRC protein; [INS1 protein co-treated with mono-(2-ethylhexyl)phthalate] results in decreased expression of STX4 protein; [INS1 protein co-treated with mono-(2-ethylhexyl)phthalate] results in decreased expression of STXBP3 protein; [INS1 protein co-treated with mono-(2-ethylhexyl)phthalate] results in decreased expression of STXBP4 protein; [INS1 protein co-treated with mono-(2-ethylhexyl)phthalate] results in decreased expression of TBC1D4 protein; [INS1 protein co-treated with mono-(2-ethylhexyl)phthalate] results in increased phosphorylation of SLC2A4 protein; mono-(2-ethylhexyl)phthalate affects the reaction [INS1 protein affects the expression of LNPEP protein]; mono-(2-ethylhexyl)phthalate affects the reaction [INS1 protein affects the expression of SNAP23 protein]; mono-(2-ethylhexyl)phthalate inhibits the reaction [INS1 protein results in increased abundance of Glycogen]; mono-(2-ethylhexyl)phthalate inhibits the reaction [INS1 protein results in increased expression of ARRB2 protein]; mono-(2-ethylhexyl)phthalate inhibits the reaction [INS1 protein results in increased expression of SLC2A4 protein]; mono-(2-ethylhexyl)phthalate inhibits the reaction [INS1 protein results in increased phosphorylation of AKT1 protein]; mono-(2-ethylhexyl)phthalate inhibits the reaction [INS1 protein results in increased phosphorylation of GSK3B protein]; mono-(2-ethylhexyl)phthalate inhibits the reaction [INS1 protein results in increased phosphorylation of TBC1D4 protein]; mono-(2-ethylhexyl)phthalate inhibits the reaction [INS1 protein results in increased uptake of Deoxyglucose] mono-(2-ethylhexyl)phthalate results in increased expression of INS1 mRNA 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [mono-(2-ethylhexyl)phthalate promotes the reaction [INS1 protein results in increased uptake of Glucose]]; [INS1 protein co-treated with mono-(2-ethylhexyl)phthalate] results in decreased expression of IRS1 protein; Akt-I-1,2 compound inhibits the reaction [mono-(2-ethylhexyl)phthalate promotes the reaction [INS1 protein results in increased uptake of Glucose]]; Cytochalasin B inhibits the reaction [mono-(2-ethylhexyl)phthalate promotes the reaction [INS1 protein results in increased uptake of Glucose]]; mono-(2-ethylhexyl)phthalate promotes the reaction [INS1 protein results in increased uptake of Glucose]; Wortmannin inhibits the reaction [mono-(2-ethylhexyl)phthalate promotes the reaction [INS1 protein results in increased uptake of Glucose]] |
CTD |
PMID:25543134 PMID:27384973 PMID:28526321 PMID:31009676 |
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NCBI chr 1:251,244,973...251,245,540
Ensembl chr 1:251,244,973...251,245,536
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G |
Ins2 |
insulin 2 |
decreases activity multiple interactions |
ISO |
mono-(2-ethylhexyl)phthalate results in decreased activity of INS protein mono-(2-ethylhexyl)phthalate inhibits the reaction [INS protein results in increased expression of and results in increased phosphorylation of AKT1 protein]; mono-(2-ethylhexyl)phthalate inhibits the reaction [INS protein results in increased phosphorylation of IRS1 protein]; mono-(2-ethylhexyl)phthalate promotes the reaction [INS protein results in increased phosphorylation of ERN2 protein] [mono-(2-ethylhexyl)phthalate results in decreased activity of INS protein] which results in decreased phosphorylation of GSK3B protein; [mono-(2-ethylhexyl)phthalate results in decreased activity of INS protein] which results in decreased phosphorylation of IRS1 protein; mono-(2-ethylhexyl)phthalate inhibits the reaction [INS protein results in increased abundance of Glycogen]; RBP4 protein promotes the reaction [[mono-(2-ethylhexyl)phthalate results in decreased activity of INS protein] which results in decreased phosphorylation of GSK3B protein]; RBP4 protein promotes the reaction [[mono-(2-ethylhexyl)phthalate results in decreased activity of INS protein] which results in decreased phosphorylation of IRS1 protein]; RBP4 protein promotes the reaction [mono-(2-ethylhexyl)phthalate inhibits the reaction [INS protein results in increased abundance of Glycogen]]; RBP4 protein promotes the reaction [mono-(2-ethylhexyl)phthalate results in decreased activity of INS protein] |
CTD |
PMID:31009676 PMID:31228551 |
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NCBI chr 1:197,843,277...197,992,522
Ensembl chr 1:197,843,281...197,864,775
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G |
Insl3 |
insulin-like 3 |
decreases expression multiple interactions |
EXP ISO |
mono-(2-ethylhexyl)phthalate results in decreased expression of INSL3 mRNA [Genistein co-treated with mono-(2-ethylhexyl)phthalate] results in decreased expression of INSL3 mRNA |
CTD |
PMID:22087261 PMID:27181934 |
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NCBI chr16:18,398,682...18,400,566
Ensembl chr16:18,384,829...18,400,560
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G |
Insr |
insulin receptor |
multiple interactions |
EXP |
[INS1 protein co-treated with mono-(2-ethylhexyl)phthalate] results in decreased expression of and results in decreased phosphorylation of INSR protein |
CTD |
PMID:28526321 |
|
NCBI chr12:1,193,193...1,330,976
Ensembl chr12:1,197,100...1,330,883
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G |
Iqgap2 |
IQ motif containing GTPase activating protein 2 |
increases expression |
ISO |
mono-(2-ethylhexyl)phthalate results in increased expression of IQGAP2 mRNA |
CTD |
PMID:22401849 |
|
NCBI chr 2:26,894,836...27,170,270
Ensembl chr 2:26,894,825...27,170,279
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G |
Irf1 |
interferon regulatory factor 1 |
increases expression multiple interactions |
ISO |
mono-(2-ethylhexyl)phthalate results in increased expression of IRF1 mRNA; mono-(2-ethylhexyl)phthalate results in increased expression of IRF1 protein IRF1 protein promotes the reaction [mono-(2-ethylhexyl)phthalate results in increased expression of YAP1 mRNA]; IRF1 protein promotes the reaction [mono-(2-ethylhexyl)phthalate results in increased expression of YAP1 protein] |
CTD |
PMID:31351048 |
|
NCBI chr10:37,917,155...37,924,166
Ensembl chr10:37,916,670...37,924,166
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G |
Irs1 |
insulin receptor substrate 1 |
decreases expression multiple interactions decreases phosphorylation |
ISO EXP |
mono-(2-ethylhexyl)phthalate results in decreased expression of IRS1 mRNA; mono-(2-ethylhexyl)phthalate results in decreased expression of IRS1 protein [INS1 protein co-treated with mono-(2-ethylhexyl)phthalate] results in decreased expression of IRS1 protein; mono-(2-ethylhexyl)phthalate inhibits the reaction [INS protein results in increased phosphorylation of IRS1 protein] [mono-(2-ethylhexyl)phthalate results in decreased activity of INS protein] which results in decreased phosphorylation of IRS1 protein; RBP4 protein promotes the reaction [[mono-(2-ethylhexyl)phthalate results in decreased activity of INS protein] which results in decreased phosphorylation of IRS1 protein]; RBP4 protein promotes the reaction [mono-(2-ethylhexyl)phthalate results in decreased phosphorylation of IRS1 protein] |
CTD |
PMID:25543134 PMID:28526321 PMID:31009676 PMID:31228551 |
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NCBI chr 9:83,552,964...83,605,797
Ensembl chr 9:83,548,944...83,606,122
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G |
Irs2 |
insulin receptor substrate 2 |
increases expression |
ISO |
mono-(2-ethylhexyl)phthalate results in increased expression of IRS2 mRNA |
CTD |
PMID:25543134 |
|
NCBI chr16:78,488,249...78,512,482
Ensembl chr16:78,485,045...78,512,482
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G |
Irx3 |
iroquois homeobox 3 |
affects expression |
ISO |
mono-(2-ethylhexyl)phthalate affects the expression of IRX3 mRNA |
CTD |
PMID:21195148 |
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NCBI chr19:15,211,882...15,215,323
Ensembl chr19:15,211,878...15,215,317
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G |
Irx5 |
iroquois homeobox 5 |
affects expression |
ISO |
mono-(2-ethylhexyl)phthalate affects the expression of IRX5 mRNA |
CTD |
PMID:21195148 |
|
NCBI chr19:14,639,052...14,643,911
Ensembl chr19:14,624,225...14,642,318
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G |
Itga3 |
integrin subunit alpha 3 |
decreases expression |
ISO |
mono-(2-ethylhexyl)phthalate results in decreased expression of ITGA3 mRNA |
CTD |
PMID:22401849 |
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NCBI chr10:79,990,160...80,022,206
Ensembl chr10:79,990,161...80,022,118
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G |
Itgb3 |
integrin subunit beta 3 |
decreases expression |
ISO |
mono-(2-ethylhexyl)phthalate results in decreased expression of ITGB3 mRNA |
CTD |
PMID:22401849 |
|
NCBI chr10:89,509,917...89,564,679
Ensembl chr10:89,509,989...89,564,679
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G |
Itgb4 |
integrin subunit beta 4 |
decreases expression |
ISO |
mono-(2-ethylhexyl)phthalate results in decreased expression of ITGB4 mRNA |
CTD |
PMID:22401849 |
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NCBI chr10:101,206,657...101,243,012
Ensembl chr10:101,206,665...101,243,012
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G |
Itih1 |
inter-alpha trypsin inhibitor, heavy chain 1 |
decreases expression |
ISO |
mono-(2-ethylhexyl)phthalate results in decreased expression of ITIH1 mRNA |
CTD |
PMID:22401849 |
|
NCBI chr16:6,122,246...6,136,363
Ensembl chr16:6,122,248...6,136,363
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G |
Jakmip3 |
janus kinase and microtubule interacting protein 3 |
decreases expression |
ISO |
mono-(2-ethylhexyl)phthalate results in decreased expression of JAKMIP3 mRNA |
CTD |
PMID:22401849 |
|
NCBI chr 1:193,753,134...193,881,105
Ensembl chr 1:193,811,513...193,881,104
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G |
Jarid2 |
jumonji and AT-rich interaction domain containing 2 |
decreases expression |
ISO |
mono-(2-ethylhexyl)phthalate results in decreased expression of JARID2 mRNA |
CTD |
PMID:22401849 |
|
NCBI chr17:19,777,487...19,957,696
Ensembl chr17:19,777,266...19,955,690
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G |
Jun |
Jun proto-oncogene, AP-1 transcription factor subunit |
increases expression |
EXP ISO |
mono-(2-ethylhexyl)phthalate results in increased expression of JUN mRNA |
CTD |
PMID:8764118 PMID:9013627 PMID:16809437 |
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NCBI chr 5:109,894,175...109,897,268
Ensembl chr 5:109,893,145...109,897,656
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G |
Junb |
JunB proto-oncogene, AP-1 transcription factor subunit |
increases expression multiple interactions |
EXP ISO |
mono-(2-ethylhexyl)phthalate results in increased expression of JUNB mRNA 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine inhibits the reaction [mono-(2-ethylhexyl)phthalate results in increased expression of JUNB mRNA] |
CTD |
PMID:8764118 PMID:16809437 |
|
NCBI chr19:23,176,265...23,178,049
Ensembl chr19:23,176,294...23,178,035
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G |
Kalrn |
kalirin, RhoGEF kinase |
decreases expression |
ISO |
mono-(2-ethylhexyl)phthalate results in decreased expression of KALRN mRNA |
CTD |
PMID:22401849 |
|
NCBI chr11:66,198,155...66,803,166
Ensembl chr11:66,198,173...66,797,610
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G |
Kcnab3 |
potassium voltage-gated channel subfamily A regulatory beta subunit 3 |
decreases expression |
ISO |
mono-(2-ethylhexyl)phthalate results in decreased expression of KCNAB3 mRNA |
CTD |
PMID:22401849 |
|
NCBI chr10:54,047,830...54,056,401
Ensembl chr10:54,047,825...54,054,174
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G |
Kcnj16 |
potassium inwardly-rectifying channel, subfamily J, member 16 |
decreases expression |
ISO |
mono-(2-ethylhexyl)phthalate results in decreased expression of KCNJ16 mRNA |
CTD |
PMID:22401849 |
|
NCBI chr10:95,990,009...96,021,356
Ensembl chr10:95,960,725...96,021,702
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G |
Kcnk6 |
potassium two pore domain channel subfamily K member 6 |
increases expression |
EXP |
mono-(2-ethylhexyl)phthalate results in increased expression of KCNK6 mRNA |
CTD |
PMID:16809437 |
|
NCBI chr 1:84,525,613...84,533,948
Ensembl chr 1:84,525,590...84,534,677
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G |
Kdm5d |
lysine demethylase 5D |
increases expression |
ISO |
mono-(2-ethylhexyl)phthalate results in increased expression of KDM5D mRNA |
CTD |
PMID:22401849 |
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NCBI chr Y:527,069...624,019
Ensembl chr Y:530,401...624,018
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G |
Kif21b |
kinesin family member 21B |
increases expression |
ISO |
mono-(2-ethylhexyl)phthalate results in increased expression of KIF21B mRNA |
CTD |
PMID:22401849 |
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NCBI chr13:47,576,142...47,626,112
Ensembl chr13:47,576,160...47,626,127
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G |
Kif27 |
kinesin family member 27 |
affects expression |
ISO |
mono-(2-ethylhexyl)phthalate affects the expression of KIF27 mRNA |
CTD |
PMID:21195148 |
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NCBI chr17:6,299,544...6,375,106
Ensembl chr17:6,299,569...6,369,768
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G |
Kif5c |
kinesin family member 5C |
increases expression |
ISO |
mono-(2-ethylhexyl)phthalate results in increased expression of KIF5C mRNA |
CTD |
PMID:22401849 |
|
NCBI chr 3:34,032,082...34,185,597
Ensembl chr 3:34,032,105...34,182,413
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G |
Kif6 |
kinesin family member 6 |
increases expression |
ISO |
mono-(2-ethylhexyl)phthalate results in increased expression of KIF6 mRNA |
CTD |
PMID:22401849 |
|
NCBI chr 9:11,076,203...11,373,205
Ensembl chr 9:11,072,824...11,373,006
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G |
Kl |
Klotho |
decreases expression |
ISO |
mono-(2-ethylhexyl)phthalate results in decreased expression of KL mRNA |
CTD |
PMID:22401849 |
|
NCBI chr12:490,402...531,417
Ensembl chr12:490,399...530,080
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G |
Klf10 |
KLF transcription factor 10 |
affects expression |
ISO |
mono-(2-ethylhexyl)phthalate affects the expression of KLF10 mRNA |
CTD |
PMID:21195148 |
|
NCBI chr 7:69,467,658...69,473,726
Ensembl chr 7:69,465,619...69,473,994
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G |
Klf11 |
KLF transcription factor 11 |
affects expression |
ISO |
mono-(2-ethylhexyl)phthalate affects the expression of KLF11 mRNA |
CTD |
PMID:21195148 |
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NCBI chr 6:41,285,699...41,297,548
Ensembl chr 6:41,285,842...41,297,550
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G |
Klf15 |
KLF transcription factor 15 |
decreases expression |
ISO |
mono-(2-ethylhexyl)phthalate results in decreased expression of KLF15 mRNA |
CTD |
PMID:25543134 |
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NCBI chr 4:122,965,718...122,978,403
Ensembl chr 4:122,965,807...122,978,374
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G |
Klhdc4 |
kelch domain containing 4 |
decreases expression |
ISO |
mono-(2-ethylhexyl)phthalate results in decreased expression of KLHDC4 mRNA |
CTD |
PMID:22401849 |
|
NCBI chr19:49,860,975...49,894,027
Ensembl chr19:49,860,967...49,894,868
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G |
Kmo |
kynurenine 3-monooxygenase |
decreases expression |
ISO |
mono-(2-ethylhexyl)phthalate results in decreased expression of KMO mRNA |
CTD |
PMID:22401849 |
|
NCBI chr13:87,557,080...87,589,334
Ensembl chr13:87,557,286...87,588,881
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G |
Kndc1 |
kinase non-catalytic C-lobe domain containing 1 |
increases expression |
ISO |
mono-(2-ethylhexyl)phthalate results in increased expression of KNDC1 mRNA |
CTD |
PMID:22401849 |
|
NCBI chr 1:194,689,962...194,738,353
Ensembl chr 1:194,690,135...194,738,362
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G |
Large2 |
LARGE xylosyl- and glucuronyltransferase 2 |
increases expression |
ISO |
mono-(2-ethylhexyl)phthalate results in increased expression of LARGE2 mRNA |
CTD |
PMID:22401849 |
|
NCBI chr 3:78,334,627...78,347,167
Ensembl chr 3:78,336,056...78,342,184
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G |
Lats1 |
large tumor suppressor kinase 1 |
multiple interactions |
ISO |
LATS1 protein inhibits the reaction [mono-(2-ethylhexyl)phthalate results in increased stability of YAP1 protein] |
CTD |
PMID:31351048 |
|
NCBI chr 1:2,160,411...2,193,640
Ensembl chr 1:2,160,411...2,193,640
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G |
Lbh |
LBH regulator of WNT signaling pathway |
affects expression |
ISO |
mono-(2-ethylhexyl)phthalate affects the expression of LBH mRNA |
CTD |
PMID:21195148 |
|
NCBI chr 6:22,569,238...22,593,056
Ensembl chr 6:22,568,834...22,593,079
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G |
Lfng |
LFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase |
decreases expression |
ISO |
mono-(2-ethylhexyl)phthalate results in decreased expression of LFNG mRNA |
CTD |
PMID:22321834 |
|
NCBI chr12:14,030,551...14,038,996
Ensembl chr12:14,018,333...14,039,008
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G |
Lgals7 |
galectin 7 |
decreases expression |
ISO |
mono-(2-ethylhexyl)phthalate results in decreased expression of LGALS7 mRNA |
CTD |
PMID:22401849 |
|
NCBI chr 1:84,148,612...84,152,016
Ensembl chr 1:84,150,252...84,152,015
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G |
Lgi1 |
leucine-rich, glioma inactivated 1 |
increases expression |
ISO |
mono-(2-ethylhexyl)phthalate results in increased expression of LGI1 mRNA |
CTD |
PMID:22401849 |
|
NCBI chr 1:236,043,376...236,084,270
Ensembl chr 1:236,042,954...236,084,616
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G |
Lgmn |
legumain |
decreases expression |
ISO |
mono-(2-ethylhexyl)phthalate results in decreased expression of LGMN mRNA |
CTD |
PMID:22401849 |
|
NCBI chr 6:121,544,048...121,582,495
Ensembl chr 6:121,544,053...121,582,480
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G |
Lgr4 |
leucine-rich repeat-containing G protein-coupled receptor 4 |
decreases expression |
ISO |
mono-(2-ethylhexyl)phthalate results in decreased expression of LGR4 mRNA |
CTD |
PMID:22401849 |
|
NCBI chr 3:96,447,385...96,550,006
Ensembl chr 3:96,447,858...96,548,899
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G |
Lgr5 |
leucine rich repeat containing G protein coupled receptor 5 |
affects expression |
ISO |
mono-(2-ethylhexyl)phthalate affects the expression of LGR5 mRNA |
CTD |
PMID:21195148 |
|
NCBI chr 7:51,087,059...51,221,882
Ensembl chr 7:51,088,239...51,222,446
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G |
Lhb |
luteinizing hormone subunit beta |
multiple interactions decreases expression |
EXP ISO |
mono-(2-ethylhexyl)phthalate inhibits the reaction [LHB protein results in increased secretion of Testosterone] mono-(2-ethylhexyl)phthalate results in decreased expression of LHB mRNA mono-(2-ethylhexyl)phthalate inhibits the reaction [LHB protein results in increased expression of STAR protein]; mono-(2-ethylhexyl)phthalate inhibits the reaction [LHB protein results in increased secretion of Progesterone] |
CTD |
PMID:19440488 PMID:34627990 PMID:34954075 |
|
NCBI chr 1:95,898,269...95,901,973
Ensembl chr 1:95,900,984...95,901,972 Ensembl chr 1:95,900,984...95,901,972
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G |
Lhcgr |
luteinizing hormone/choriogonadotropin receptor |
decreases expression multiple interactions |
ISO |
mono-(2-ethylhexyl)phthalate results in decreased expression of LHCGR mRNA [monoethyl phthalate co-treated with mono-(2-ethylhexyl)phthalate co-treated with mono-isobutyl phthalate co-treated with monoisononylphthalate co-treated with mono-benzyl phthalate] results in decreased expression of LHCGR mRNA |
CTD |
PMID:22401849 PMID:31884101 |
|
NCBI chr 6:5,661,871...5,728,109
Ensembl chr 6:5,661,871...5,724,521
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G |
Lhpp |
phospholysine phosphohistidine inorganic pyrophosphate phosphatase |
affects expression |
ISO |
mono-(2-ethylhexyl)phthalate affects the expression of LHPP mRNA |
CTD |
PMID:21195148 |
|
NCBI chr 1:187,403,390...187,494,577
Ensembl chr 1:187,403,433...187,494,578
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G |
Lima1 |
LIM domain and actin binding 1 |
increases expression |
ISO |
mono-(2-ethylhexyl)phthalate results in increased expression of LIMA1 mRNA |
CTD |
PMID:22401849 |
|
NCBI chr 7:130,901,717...131,001,573
Ensembl chr 7:130,901,717...131,001,473
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G |
Lipa |
lipase A, lysosomal acid type |
increases expression |
EXP |
mono-(2-ethylhexyl)phthalate results in increased expression of LIP1 mRNA |
CTD |
PMID:16809437 |
|
NCBI chr 1:232,024,351...232,167,329
Ensembl chr 1:232,024,356...232,057,633
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G |
Lipe |
lipase E, hormone sensitive type |
increases expression increases phosphorylation multiple interactions |
ISO |
mono-(2-ethylhexyl)phthalate results in increased expression of LIPE mRNA mono-(2-ethylhexyl)phthalate results in increased phosphorylation of LIPE protein [Genistein co-treated with mono-(2-ethylhexyl)phthalate] results in increased expression of LIPE mRNA; Acetylcysteine inhibits the reaction [mono-(2-ethylhexyl)phthalate results in increased phosphorylation of LIPE protein] |
CTD |
PMID:25543134 PMID:27181934 PMID:30648648 |
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NCBI chr 1:80,965,612...80,984,313
Ensembl chr 1:80,965,627...80,984,310
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G |
Lipg |
lipase G, endothelial type |
decreases expression |
ISO |
mono-(2-ethylhexyl)phthalate results in decreased expression of LIPG mRNA |
CTD |
PMID:22401849 |
|
NCBI chr18:68,514,923...68,536,105
Ensembl chr18:68,514,923...68,536,260
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G |
Llgl2 |
LLGL scribble cell polarity complex component 2 |
increases expression |
ISO |
mono-(2-ethylhexyl)phthalate results in increased expression of LLGL2 mRNA |
CTD |
PMID:22401849 |
|
NCBI chr10:101,050,978...101,086,527
Ensembl chr10:101,051,408...101,086,525
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G |
Lnpep |
leucyl and cystinyl aminopeptidase |
multiple interactions |
EXP |
mono-(2-ethylhexyl)phthalate affects the reaction [INS1 protein affects the expression of LNPEP protein] |
CTD |
PMID:28526321 |
|
NCBI chr 1:58,258,642...58,355,532
Ensembl chr 1:58,258,642...58,354,544
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G |
LOC120103107 |
PRAME family member 12-like |
decreases expression |
ISO |
mono-(2-ethylhexyl)phthalate results in decreased expression of ZFP27 mRNA |
CTD |
PMID:22401849 |
|
NCBI chr 5:156,009,794...156,012,390
Ensembl chr 5:156,009,836...156,012,357
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G |
Loxl2 |
lysyl oxidase-like 2 |
decreases expression |
ISO |
mono-(2-ethylhexyl)phthalate results in decreased expression of LOXL2 mRNA |
CTD |
PMID:22401849 |
|
NCBI chr15:44,683,449...44,773,067
Ensembl chr15:44,683,880...44,773,067
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G |
Lpcat3 |
lysophosphatidylcholine acyltransferase 3 |
decreases expression |
ISO |
mono-(2-ethylhexyl)phthalate results in decreased expression of LPCAT3 mRNA |
CTD |
PMID:22401849 |
|
NCBI chr 4:157,468,397...157,509,889
Ensembl chr 4:157,468,290...157,509,880
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G |
Lrig1 |
leucine-rich repeats and immunoglobulin-like domains 1 |
affects expression |
ISO |
mono-(2-ethylhexyl)phthalate affects the expression of LRIG1 mRNA |
CTD |
PMID:21195148 |
|
NCBI chr 4:127,130,899...127,230,956
Ensembl chr 4:127,130,898...127,231,513
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G |
Lrrc4 |
leucine rich repeat containing 4 |
affects expression |
ISO |
mono-(2-ethylhexyl)phthalate affects the expression of LRRC4 mRNA |
CTD |
PMID:21195148 |
|
NCBI chr 4:57,433,518...57,437,114
Ensembl chr 4:57,433,428...57,437,911
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|
G |
Lrrc56 |
leucine rich repeat containing 56 |
affects expression |
ISO |
mono-(2-ethylhexyl)phthalate affects the expression of LRRC56 mRNA |
CTD |
PMID:21195148 |
|
NCBI chr 1:196,299,843...196,315,170
Ensembl chr 1:196,299,846...196,315,172
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|
G |
Lrrc66 |
leucine rich repeat containing 66 |
decreases expression |
ISO |
mono-(2-ethylhexyl)phthalate results in decreased expression of LRRC66 mRNA |
CTD |
PMID:22401849 |
|
NCBI chr14:34,581,318...34,604,534
Ensembl chr14:34,581,240...34,604,541
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G |
Lrrfip1 |
LRR binding FLII interacting protein 1 |
decreases expression |
ISO |
mono-(2-ethylhexyl)phthalate results in decreased expression of LRRFIP1 mRNA |
CTD |
PMID:22401849 |
|
NCBI chr 9:91,592,032...91,720,250
Ensembl chr 9:91,643,197...91,720,250
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|
G |
Ltbp1 |
latent transforming growth factor beta binding protein 1 |
decreases expression |
ISO |
mono-(2-ethylhexyl)phthalate results in decreased expression of LTBP1 mRNA |
CTD |
PMID:22401849 |
|
NCBI chr 6:20,029,629...20,425,339
Ensembl chr 6:20,029,629...20,425,349
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G |
Lurap1l |
leucine rich adaptor protein 1-like |
increases expression |
EXP |
mono-(2-ethylhexyl)phthalate results in increased expression of LURAP1L mRNA |
CTD |
PMID:16809437 |
|
NCBI chr 5:95,362,005...95,409,439
Ensembl chr 5:95,362,005...95,409,438
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|
G |
Luzp4 |
leucine zipper protein 4 |
decreases expression |
ISO |
mono-(2-ethylhexyl)phthalate results in decreased expression of OTT mRNA |
CTD |
PMID:22401849 |
|
NCBI chr X:111,280,490...111,321,363
Ensembl chr X:111,280,549...111,321,359
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|
G |
Ly75 |
lymphocyte antigen 75 |
decreases expression |
ISO |
mono-(2-ethylhexyl)phthalate results in decreased expression of LY75 mRNA |
CTD |
PMID:22401849 |
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NCBI chr 3:44,764,702...44,852,219
Ensembl chr 3:44,765,122...44,852,374
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G |
Maff |
MAF bZIP transcription factor F |
increases expression |
EXP |
mono-(2-ethylhexyl)phthalate results in increased expression of MAFF mRNA |
CTD |
PMID:16809437 |
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NCBI chr 7:110,912,499...110,923,851
Ensembl chr 7:110,912,499...110,923,851
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G |
Mafk |
MAF bZIP transcription factor K |
increases expression |
EXP |
mono-(2-ethylhexyl)phthalate results in increased expression of MAFK mRNA |
CTD |
PMID:16809437 |
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NCBI chr12:14,834,628...14,856,414
Ensembl chr12:14,833,984...14,837,048 Ensembl chr12:14,833,984...14,837,048
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G |
Mageb18 |
MAGE family member B18 |
increases expression |
ISO |
mono-(2-ethylhexyl)phthalate results in increased expression of MAGEB18 mRNA |
CTD |
PMID:22401849 |
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NCBI chr X:56,885,991...56,888,245
Ensembl chr X:56,885,991...56,888,245
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G |
Mak |
male germ cell-associated kinase |
affects expression |
ISO |
mono-(2-ethylhexyl)phthalate affects the expression of MAK mRNA |
CTD |
PMID:21195148 |
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NCBI chr17:23,683,674...23,731,125
Ensembl chr17:23,693,878...23,730,001
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G |
Map1b |
microtubule-associated protein 1B |
increases expression |
EXP |
mono-(2-ethylhexyl)phthalate results in increased expression of MAP1B mRNA |
CTD |
PMID:16809437 |
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NCBI chr 2:30,817,261...30,910,458
Ensembl chr 2:30,817,261...30,910,317
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G |
Mapk1 |
mitogen activated protein kinase 1 |
multiple interactions affects phosphorylation increases phosphorylation |
ISO |
mono-(2-ethylhexyl)phthalate inhibits the reaction [GDNF protein results in increased phosphorylation of MAPK1 protein] [bisphenol A co-treated with mono-(2-ethylhexyl)phthalate] results in increased phosphorylation of MAPK1 protein; [mono-(2-ethylhexyl)phthalate co-treated with bisphenol A] inhibits the reaction [HDAC6 protein affects the phosphorylation of MAPK1 protein] mono-(2-ethylhexyl)phthalate affects the phosphorylation of MAPK1 protein mono-(2-ethylhexyl)phthalate results in increased phosphorylation of MAPK1 protein |
CTD |
PMID:22564763 PMID:28390675 PMID:30810372 PMID:34910997 |
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NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616
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G |
Mapk3 |
mitogen activated protein kinase 3 |
multiple interactions affects phosphorylation increases phosphorylation |
ISO |
mono-(2-ethylhexyl)phthalate inhibits the reaction [GDNF protein results in increased phosphorylation of MAPK3 protein] [bisphenol A co-treated with mono-(2-ethylhexyl)phthalate] results in increased phosphorylation of MAPK3 protein; [mono-(2-ethylhexyl)phthalate co-treated with bisphenol A] inhibits the reaction [HDAC6 protein affects the phosphorylation of MAPK3 protein] mono-(2-ethylhexyl)phthalate affects the phosphorylation of MAPK3 protein mono-(2-ethylhexyl)phthalate results in increased phosphorylation of MAPK3 protein |
CTD |
PMID:22564763 PMID:28390675 PMID:30810372 PMID:34910997 |
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NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863
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G |
Mapk8 |
mitogen-activated protein kinase 8 |
affects phosphorylation |
ISO |
mono-(2-ethylhexyl)phthalate affects the phosphorylation of MAPK8 protein |
CTD |
PMID:30810372 |
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NCBI chr16:8,638,897...8,721,960
Ensembl chr16:8,638,924...8,721,981
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G |
Mapkapk3 |
MAPK activated protein kinase 3 |
decreases expression |
ISO |
mono-(2-ethylhexyl)phthalate results in decreased expression of MAPKAPK3 mRNA |
CTD |
PMID:22401849 |
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NCBI chr 8:107,929,754...107,963,638
Ensembl chr 8:107,929,762...107,963,568
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G |
Mapt |
microtubule-associated protein tau |
increases expression |
ISO |
mono-(2-ethylhexyl)phthalate results in increased expression of MAPT mRNA |
CTD |
PMID:22401849 |
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NCBI chr10:89,138,644...89,236,137
Ensembl chr10:89,138,627...89,236,129
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G |
Marco |
macrophage receptor with collagenous structure |
multiple interactions |
ISO |
mono-(2-ethylhexyl)phthalate inhibits the reaction [[Lipopolysaccharides co-treated with IFNG protein] results in increased expression of MARCO mRNA] |
CTD |
PMID:29718165 |
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NCBI chr13:31,616,278...31,648,521
Ensembl chr13:31,616,278...31,648,521
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G |
Mars1 |
methionyl-tRNA synthetase 1 |
increases expression |
ISO |
mono-(2-ethylhexyl)phthalate results in increased expression of MARS1 mRNA |
CTD |
PMID:22321834 |
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NCBI chr 7:63,121,142...63,138,550
Ensembl chr 7:63,121,142...63,138,495
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G |
Mbd3l2 |
methyl-CpG binding domain protein 3-like 2 |
decreases expression |
ISO |
mono-(2-ethylhexyl)phthalate results in decreased expression of MBD3L2 mRNA |
CTD |
PMID:22401849 |
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NCBI chr 8:15,607,477...15,614,046
Ensembl chr 8:15,611,214...15,612,563
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G |
Mbp |
myelin basic protein |
decreases expression |
ISO |
mono-(2-ethylhexyl)phthalate results in decreased expression of MBP mRNA |
CTD |
PMID:22401849 |
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NCBI chr18:75,855,878...75,966,404
Ensembl chr18:75,855,878...75,966,404
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G |
Mcam |
melanoma cell adhesion molecule |
multiple interactions |
ISO |
[mono-(2-ethylhexyl)phthalate co-treated with Genistein] results in increased expression of MCAM mRNA |
CTD |
PMID:34942354 |
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NCBI chr 8:44,479,391...44,487,575
Ensembl chr 8:44,479,376...44,487,571
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G |
Mdga1 |
MAM domain containing glycosylphosphatidylinositol anchor 1 |
decreases expression |
ISO |
mono-(2-ethylhexyl)phthalate results in decreased expression of MDGA1 mRNA |
CTD |
PMID:22401849 |
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NCBI chr20:7,900,327...7,963,471
Ensembl chr20:7,904,358...7,963,471
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G |
Mdm2 |
MDM2 proto-oncogene |
decreases expression |
ISO |
mono-(2-ethylhexyl)phthalate results in decreased expression of MDM2 protein |
CTD |
PMID:24706461 |
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NCBI chr 7:53,290,660...53,315,205
Ensembl chr 7:53,290,664...53,314,915
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G |
Med1 |
mediator complex subunit 1 |
multiple interactions |
ISO |
mono-(2-ethylhexyl)phthalate promotes the reaction [PPARA protein binds to MED1 protein] |
CTD |
PMID:20123618 |
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NCBI chr10:83,145,538...83,189,260
Ensembl chr10:83,145,568...83,189,299
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G |
Meox1 |
mesenchyme homeobox 1 |
increases expression |
ISO |
mono-(2-ethylhexyl)phthalate results in increased expression of MEOX1 mRNA |
CTD |
PMID:31711903 |
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NCBI chr10:86,818,450...86,837,563
Ensembl chr10:86,818,478...86,837,660
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G |
Mep1b |
meprin A subunit beta |
decreases expression |
ISO |
mono-(2-ethylhexyl)phthalate results in decreased expression of MEP1B mRNA |
CTD |
PMID:22401849 |
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NCBI chr18:12,366,126...12,392,840
Ensembl chr18:12,365,289...12,392,840
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G |
Mesp2 |
mesoderm posterior bHLH transcription factor 2 |
decreases expression |
ISO |
mono-(2-ethylhexyl)phthalate results in decreased expression of MESP2 mRNA |
CTD |
PMID:31711903 |
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NCBI chr 1:133,756,601...133,759,207
Ensembl chr 1:133,756,601...133,759,198
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G |
Mettl14 |
methyltransferase 14, N6-adenosine-methyltransferase subunit |
decreases expression multiple interactions |
ISO |
mono-(2-ethylhexyl)phthalate results in decreased expression of METTL14 mRNA; mono-(2-ethylhexyl)phthalate results in decreased expression of METTL14 protein METTL14 protein affects the reaction [mono-(2-ethylhexyl)phthalate results in decreased expression of SCARB1 mRNA]; mono-(2-ethylhexyl)phthalate affects the reaction [METTL14 protein affects the expression of SCARB1 mRNA] |
CTD |
PMID:31875672 |
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NCBI chr 2:211,530,598...211,546,858
Ensembl chr 2:211,530,602...211,546,821
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G |
Mettl3 |
methyltransferase 3, N6-adenosine-methyltransferase complex catalytic subunit |
decreases expression |
ISO |
mono-(2-ethylhexyl)phthalate results in decreased expression of METTL3 mRNA |
CTD |
PMID:31875672 |
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NCBI chr15:25,002,505...25,014,097
Ensembl chr15:25,003,172...25,014,041
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G |
Mgst2 |
microsomal glutathione S-transferase 2 |
decreases expression |
ISO |
mono-(2-ethylhexyl)phthalate results in decreased expression of MGST2 mRNA |
CTD |
PMID:22401849 |
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NCBI chr 2:135,679,524...135,715,828
Ensembl chr 2:135,693,557...135,715,828
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G |
Mif |
macrophage migration inhibitory factor |
increases expression |
ISO |
mono-(2-ethylhexyl)phthalate results in increased expression of MIF protein |
CTD |
PMID:27384973 |
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NCBI chr20:12,790,919...12,791,784
Ensembl chr20:12,790,902...12,799,504
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G |
Mir101a |
microRNA 101a |
increases expression |
ISO |
mono-(2-ethylhexyl)phthalate results in increased expression of MIR101A mRNA |
CTD |
PMID:31875672 |
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NCBI chr 5:115,966,332...115,966,406
Ensembl chr 5:115,966,328...115,966,410
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G |
Mir106b |
microRNA 106b |
multiple interactions |
ISO |
[Diethylhexyl Phthalate results in increased abundance of mono-(2-ethylhexyl)phthalate] which affects the expression of MIR106B |
CTD |
PMID:30481674 |
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NCBI chr12:17,043,344...17,043,425
Ensembl chr12:17,043,344...17,043,425
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G |
Mir15b |
microRNA 15b |
multiple interactions |
ISO |
[Diethylhexyl Phthalate results in increased abundance of mono-(2-ethylhexyl)phthalate] which affects the expression of MIR15B |
CTD |
PMID:30481674 |
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NCBI chr 2:153,245,200...153,245,297
Ensembl chr 2:153,245,200...153,245,297
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G |
Mir202 |
microRNA 202 |
decreases expression |
ISO |
mono-(2-ethylhexyl)phthalate results in decreased expression of MIR202 mRNA |
CTD |
PMID:31875672 |
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NCBI chr 1:194,754,730...194,754,801
Ensembl chr 1:194,754,730...194,754,801
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G |
Mir27b |
microRNA 27b |
decreases expression multiple interactions |
ISO |
mono-(2-ethylhexyl)phthalate results in decreased expression of MIR27B mRNA MIR27B mRNA inhibits the reaction [mono-(2-ethylhexyl)phthalate results in increased expression of PCNA mRNA]; MIR27B mRNA inhibits the reaction [mono-(2-ethylhexyl)phthalate results in increased expression of PCNA protein]; MYC protein affects the reaction [mono-(2-ethylhexyl)phthalate results in decreased expression of MIR27B mRNA] |
CTD |
PMID:30858031 |
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NCBI chr17:1,813,427...1,813,523
Ensembl chr17:1,813,426...1,813,529
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G |
Mir295-1 |
microRNA 295-1 |
multiple interactions decreases expression |
ISO |
MIR372 mRNA inhibits the reaction [mono-(2-ethylhexyl)phthalate results in increased expression of PCNA mRNA]; MIR372 mRNA inhibits the reaction [mono-(2-ethylhexyl)phthalate results in increased expression of PCNA protein] mono-(2-ethylhexyl)phthalate results in decreased expression of MIR372 mRNA |
CTD |
PMID:30858031 |
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NCBI chr 1:65,962,566...65,962,646
Ensembl chr 1:65,962,566...65,962,646
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G |
Mir532 |
microRNA 532 |
increases expression |
ISO |
mono-(2-ethylhexyl)phthalate results in increased expression of MIR532 mRNA |
CTD |
PMID:31875672 |
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NCBI chr X:15,247,315...15,247,393
Ensembl chr X:15,247,315...15,247,393
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G |
Mir542 |
microRNA 542 |
increases expression |
ISO |
mono-(2-ethylhexyl)phthalate results in increased expression of MIR542 mRNA |
CTD |
PMID:31875672 |
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NCBI chr X:132,802,623...132,802,701
Ensembl chr X:132,802,623...132,802,701
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G |
Mir877 |
microRNA 877 |
decreases expression |
ISO |
mono-(2-ethylhexyl)phthalate results in decreased expression of MIR877 mRNA |
CTD |
PMID:31875672 |
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NCBI chr20:2,811,476...2,811,560
Ensembl chr20:2,811,476...2,811,560
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G |
Mixl1 |
Mix paired-like homeobox 1 |
increases expression |
ISO |
mono-(2-ethylhexyl)phthalate results in increased expression of MIXL1 mRNA |
CTD |
PMID:22401849 |
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NCBI chr13:92,422,031...92,426,065
Ensembl chr13:92,422,031...92,426,065
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G |
Mki67 |
marker of proliferation Ki-67 |
multiple interactions |
ISO |
[monoethyl phthalate co-treated with mono-(2-ethylhexyl)phthalate co-treated with mono-isobutyl phthalate co-treated with monoisononylphthalate co-treated with mono-benzyl phthalate] results in decreased expression of MKI67 mRNA |
CTD |
PMID:31884101 |
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NCBI chr 1:190,496,319...190,522,983
Ensembl chr 1:190,496,319...190,522,762
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G |
Mlycd |
malonyl-CoA decarboxylase |
increases expression |
ISO |
mono-(2-ethylhexyl)phthalate results in increased expression of MLYCD mRNA |
CTD |
PMID:32522588 |
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NCBI chr19:47,447,931...47,463,794
Ensembl chr19:47,447,970...47,463,793
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G |
Mmel1 |
membrane metallo-endopeptidase-like 1 |
decreases expression |
ISO |
mono-(2-ethylhexyl)phthalate results in decreased expression of MMEL1 mRNA |
CTD |
PMID:22401849 |
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NCBI chr 5:165,431,278...165,461,716
Ensembl chr 5:165,431,343...165,461,716
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G |
Mmp19 |
matrix metallopeptidase 19 |
decreases expression |
ISO |
mono-(2-ethylhexyl)phthalate results in decreased expression of MMP19 mRNA |
CTD |
PMID:22401849 |
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NCBI chr 7:1,221,229...1,229,555
Ensembl chr 7:1,221,343...1,229,555
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G |
Mmp2 |
matrix metallopeptidase 2 |
increases expression affects expression multiple interactions increases secretion increases activity |
ISO |
mono-(2-ethylhexyl)phthalate results in increased expression of MMP2 mRNA; mono-(2-ethylhexyl)phthalate results in increased expression of MMP2 protein mono-(2-ethylhexyl)phthalate affects the expression of MMP2 mRNA 3-(4-methylphenylsulfonyl)-2-propenenitrile inhibits the reaction [mono-(2-ethylhexyl)phthalate results in increased expression of MMP2 mRNA]; 3-(4-methylphenylsulfonyl)-2-propenenitrile inhibits the reaction [mono-(2-ethylhexyl)phthalate results in increased expression of MMP2 protein]; [SB 3CT compound results in decreased activity of MMP2 protein] inhibits the reaction [mono-(2-ethylhexyl)phthalate results in increased secretion of MMP2 protein]; [SB 3CT compound results in decreased activity of MMP2 protein] which results in decreased susceptibility to mono-(2-ethylhexyl)phthalate; ESR1 protein affects the reaction [mono-(2-ethylhexyl)phthalate affects the expression of MMP2 mRNA]; Fulvestrant inhibits the reaction [mono-(2-ethylhexyl)phthalate results in increased expression of MMP2 mRNA]; SB 3CT compound inhibits the reaction [mono-(2-ethylhexyl)phthalate results in increased activity of MMP2 protein] |
CTD |
PMID:22321834 PMID:28390675 PMID:33631300 |
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NCBI chr19:14,154,657...14,182,870
Ensembl chr19:14,154,657...14,182,870
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G |
Mmp9 |
matrix metallopeptidase 9 |
multiple interactions affects expression increases expression decreases expression |
ISO |
2-chloro-5-nitrobenzanilide inhibits the reaction [mono-(2-ethylhexyl)phthalate results in decreased expression of MMP9 protein]; 3-(4-methylphenylsulfonyl)-2-propenenitrile inhibits the reaction [mono-(2-ethylhexyl)phthalate results in increased expression of MMP9 mRNA]; 3-(4-methylphenylsulfonyl)-2-propenenitrile inhibits the reaction [mono-(2-ethylhexyl)phthalate results in increased expression of MMP9 protein]; [bisphenol A co-treated with mono-(2-ethylhexyl)phthalate co-treated with mono-benzyl phthalate co-treated with monobutyl phthalate] results in increased secretion of MMP9 protein; ESR1 protein affects the reaction [mono-(2-ethylhexyl)phthalate affects the expression of MMP9 mRNA]; Fulvestrant inhibits the reaction [mono-(2-ethylhexyl)phthalate results in increased expression of MMP9 mRNA]; mifobate inhibits the reaction [mono-(2-ethylhexyl)phthalate results in decreased expression of MMP9 protein]; PPARG mRNA promotes the reaction [mono-(2-ethylhexyl)phthalate results in decreased expression of MMP9 protein] mono-(2-ethylhexyl)phthalate inhibits the reaction [[Lipopolysaccharides co-treated with IFNG protein] results in increased expression of MMP9 mRNA] mono-(2-ethylhexyl)phthalate results in increased expression of MMP9 mRNA; mono-(2-ethylhexyl)phthalate results in increased expression of MMP9 protein |
CTD |
PMID:28390675 PMID:28416457 PMID:29718165 PMID:30398665 PMID:33631300 |
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NCBI chr 3:153,684,158...153,692,118
Ensembl chr 3:153,683,858...153,692,120
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G |
Mov10l1 |
Mov10 like RISC complex RNA helicase 1 |
decreases expression |
ISO |
mono-(2-ethylhexyl)phthalate results in decreased expression of MOV10L1 mRNA |
CTD |
PMID:22401849 |
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NCBI chr 7:120,070,171...120,135,406
Ensembl chr 7:120,070,135...120,134,765
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G |
Mpo |
myeloperoxidase |
increases expression |
ISO |
mono-(2-ethylhexyl)phthalate results in increased expression of MPO mRNA |
CTD |
PMID:22401849 |
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NCBI chr10:72,594,458...72,608,862
Ensembl chr10:72,594,661...72,604,819
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G |
Mrc1 |
mannose receptor, C type 1 |
multiple interactions |
ISO |
[bisphenol A co-treated with mono-(2-ethylhexyl)phthalate co-treated with mono-benzyl phthalate co-treated with monobutyl phthalate] results in decreased expression of MRC1 mRNA |
CTD |
PMID:30398665 |
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NCBI chr17:77,249,187...77,330,857
Ensembl chr17:77,249,187...77,330,857
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G |
Mroh2b |
maestro heat-like repeat family member 2B |
increases expression |
ISO |
mono-(2-ethylhexyl)phthalate results in increased expression of MROH2B mRNA |
CTD |
PMID:22401849 |
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NCBI chr 2:54,003,870...54,063,992
Ensembl chr 2:54,003,862...54,063,984
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G |
Mt-nd1 |
mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 1 |
decreases expression |
ISO |
mono-(2-ethylhexyl)phthalate results in decreased expression of ND1 mRNA |
CTD |
PMID:20438828 |
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NCBI chr MT:2,740...3,694
Ensembl chr MT:2,740...3,694
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G |
Mt2A |
metallothionein 2A |
affects expression |
ISO |
mono-(2-ethylhexyl)phthalate affects the expression of MT2 mRNA |
CTD |
PMID:21195148 |
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NCBI chr19:10,832,009...10,832,783
Ensembl chr19:10,832,002...10,832,784
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G |
Mtmr7 |
myotubularin related protein 7 |
decreases expression |
ISO |
mono-(2-ethylhexyl)phthalate results in decreased expression of MTMR7 mRNA |
CTD |
PMID:22401849 |
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NCBI chr16:51,641,225...51,732,212
Ensembl chr16:51,641,190...51,732,182
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G |
Mtus1 |
microtubule associated scaffold protein 1 |
increases expression |
EXP |
mono-(2-ethylhexyl)phthalate results in increased expression of MTUS1 mRNA |
CTD |
PMID:16809437 |
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NCBI chr16:51,202,497...51,347,791
Ensembl chr16:51,253,562...51,347,793
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G |
Muc5b |
mucin 5B, oligomeric mucus/gel-forming |
decreases expression |
ISO |
mono-(2-ethylhexyl)phthalate results in decreased expression of MUC5B mRNA |
CTD |
PMID:22401849 |
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NCBI chr 1:196,916,861...196,948,830
Ensembl chr 1:196,916,825...196,949,250
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G |
Mup4 |
major urinary protein 4 |
increases expression |
ISO |
mono-(2-ethylhexyl)phthalate results in increased expression of MUP4 mRNA |
CTD |
PMID:22401849 |
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NCBI chr 5:74,961,143...74,964,686
Ensembl chr 5:74,842,319...75,061,474
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G |
Mvd |
mevalonate diphosphate decarboxylase |
decreases expression |
ISO |
mono-(2-ethylhexyl)phthalate results in decreased expression of MVD mRNA |
CTD |
PMID:22401849 |
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NCBI chr19:50,496,366...50,506,389
Ensembl chr19:50,496,367...50,507,971
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G |
Mybpc2 |
myosin binding protein C2 |
increases expression |
ISO |
mono-(2-ethylhexyl)phthalate results in increased expression of MYBPC2 mRNA |
CTD |
PMID:22401849 |
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NCBI chr 1:94,994,104...95,017,650
Ensembl chr 1:94,994,104...95,017,584
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G |
Myc |
MYC proto-oncogene, bHLH transcription factor |
affects localization multiple interactions increases expression |
ISO EXP |
mono-(2-ethylhexyl)phthalate affects the localization of MYC protein [bisphenol A co-treated with mono-(2-ethylhexyl)phthalate] results in increased expression of MYC protein; HDAC6 protein affects the reaction [[bisphenol A co-treated with mono-(2-ethylhexyl)phthalate] results in increased expression of MYC protein]; MYC protein affects the reaction [mono-(2-ethylhexyl)phthalate results in decreased expression of MIR27B mRNA]; tubastatin A inhibits the reaction [[bisphenol A co-treated with mono-(2-ethylhexyl)phthalate] results in increased expression of MYC protein] mono-(2-ethylhexyl)phthalate results in increased expression of MYC mRNA; mono-(2-ethylhexyl)phthalate results in increased expression of MYC protein |
CTD |
PMID:21832167 PMID:22321834 PMID:30858031 PMID:34910997 |
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NCBI chr 7:93,593,705...93,598,633
Ensembl chr 7:93,593,705...93,598,630
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G |
Mycn |
MYCN proto-oncogene, bHLH transcription factor |
decreases expression increases expression |
EXP |
mono-(2-ethylhexyl)phthalate results in decreased expression of MYCN mRNA mono-(2-ethylhexyl)phthalate results in increased expression of MYCN mRNA |
CTD |
PMID:16809437 |
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NCBI chr 6:35,717,764...35,723,590
Ensembl chr 6:35,717,764...35,723,590
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G |
Myh8 |
myosin heavy chain 8 |
decreases expression |
ISO |
mono-(2-ethylhexyl)phthalate results in decreased expression of MYH8 mRNA |
CTD |
PMID:22401849 |
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NCBI chr10:51,963,510...51,993,103
Ensembl chr10:51,963,510...51,993,232
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G |
Myo15a |
myosin XVA |
increases expression |
ISO |
mono-(2-ethylhexyl)phthalate results in increased expression of MYO15A mRNA |
CTD |
PMID:22401849 |
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NCBI chr10:45,277,619...45,335,953
Ensembl chr10:45,278,737...45,335,340
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G |
Myo7a |
myosin VIIA |
decreases expression |
ISO |
mono-(2-ethylhexyl)phthalate results in decreased expression of MYO7A mRNA |
CTD |
PMID:22401849 |
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NCBI chr 1:152,342,611...152,414,171
Ensembl chr 1:152,344,448...152,414,157
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G |
Myom3 |
myomesin 3 |
increases expression |
ISO |
mono-(2-ethylhexyl)phthalate results in increased expression of MYOM3 mRNA |
CTD |
PMID:22401849 |
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NCBI chr 5:147,992,737...148,043,282
Ensembl chr 5:147,992,737...148,043,274
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G |
Nalcn |
sodium leak channel, non-selective |
decreases expression |
ISO |
mono-(2-ethylhexyl)phthalate results in decreased expression of NALCN mRNA |
CTD |
PMID:22401849 |
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NCBI chr15:100,398,615...100,712,283
Ensembl chr15:100,398,615...100,741,001
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G |
Nbeal2 |
neurobeachin-like 2 |
increases expression |
ISO |
mono-(2-ethylhexyl)phthalate results in increased expression of NBEAL2 mRNA |
CTD |
PMID:22401849 |
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NCBI chr 8:110,603,220...110,633,612
Ensembl chr 8:110,599,389...110,633,707
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G |
Ncan |
neurocan |
decreases expression |
ISO |
mono-(2-ethylhexyl)phthalate results in decreased expression of NCAN mRNA |
CTD |
PMID:22401849 |
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NCBI chr16:19,301,969...19,328,436
Ensembl chr16:19,301,969...19,328,436
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G |
Ncbp2as2 |
NCBP2 antisense 2 (head to head) |
affects expression |
ISO |
mono-(2-ethylhexyl)phthalate affects the expression of NCBP2AS2 mRNA |
CTD |
PMID:29385630 |
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NCBI chr11:68,829,947...68,830,715
Ensembl chr11:68,829,983...68,830,708
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G |
Ncoa1 |
nuclear receptor coactivator 1 |
multiple interactions |
ISO |
mono-(2-ethylhexyl)phthalate promotes the reaction [NCOA1 protein binds to and results in increased activity of NR1H2 protein]; mono-(2-ethylhexyl)phthalate promotes the reaction [NCOA1 protein binds to and results in increased activity of NR1H3 protein] |
CTD |
PMID:27551952 |
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NCBI chr 6:27,232,609...27,507,992
Ensembl chr 6:27,232,611...27,475,664
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G |
Ncoa7 |
nuclear receptor coactivator 7 |
decreases expression |
ISO |
mono-(2-ethylhexyl)phthalate results in decreased expression of NCOA7 mRNA |
CTD |
PMID:22401849 |
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NCBI chr 1:26,856,228...27,016,950
Ensembl chr 1:26,856,530...27,015,871
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G |
Ncor1 |
nuclear receptor co-repressor 1 |
multiple interactions |
ISO |
mono-(2-ethylhexyl)phthalate inhibits the reaction [PPARA protein binds to NCOR1 protein] |
CTD |
PMID:20123618 |
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NCBI chr10:46,999,536...47,142,294
Ensembl chr10:46,999,536...47,141,032
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G |
Ndrg1 |
N-myc downstream regulated 1 |
affects expression |
ISO |
mono-(2-ethylhexyl)phthalate affects the expression of NDRG1 mRNA |
CTD |
PMID:21195148 |
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NCBI chr 7:98,684,487...98,725,869
Ensembl chr 7:98,684,487...98,725,880
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G |
Ndufa3 |
NADH:ubiquinone oxidoreductase subunit A3 |
decreases expression |
ISO |
mono-(2-ethylhexyl)phthalate results in decreased expression of NDUFA3 mRNA |
CTD |
PMID:27167697 |
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NCBI chr 1:65,597,562...65,600,242
Ensembl chr 1:65,597,578...65,600,235
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G |
Ndufa6 |
NADH:ubiquinone oxidoreductase subunit A6 |
decreases expression |
ISO |
mono-(2-ethylhexyl)phthalate results in decreased expression of NDUFA6 mRNA |
CTD |
PMID:27167697 |
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NCBI chr 7:113,866,382...113,870,239
Ensembl chr 7:113,866,382...113,870,239
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G |
Ndufa7 |
NADH:ubiquinone oxidoreductase subunit A7 |
decreases expression |
ISO |
mono-(2-ethylhexyl)phthalate results in decreased expression of NDUFA7 mRNA |
CTD |
PMID:27167697 |
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NCBI chr 7:14,609,283...14,622,064
Ensembl chr 7:14,609,146...14,631,976
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G |
Ndufs5 |
NADH:ubiquinone oxidoreductase subunit S5 |
decreases expression |
ISO |
mono-(2-ethylhexyl)phthalate results in decreased expression of NDUFS5 mRNA |
CTD |
PMID:27167697 |
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NCBI chr 5:135,974,029...135,979,705
Ensembl chr 5:135,974,034...135,979,603
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G |
Neb |
nebulin |
affects expression |
ISO |
mono-(2-ethylhexyl)phthalate affects the expression of NEB mRNA |
CTD |
PMID:22401849 |
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NCBI chr 3:36,613,677...36,811,618
Ensembl chr 3:36,613,716...36,811,574
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G |
Nek1 |
NIMA-related kinase 1 |
increases expression |
ISO |
mono-(2-ethylhexyl)phthalate results in increased expression of NEK1 mRNA |
CTD |
PMID:22401849 |
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NCBI chr16:28,998,229...29,125,426
Ensembl chr16:28,998,231...29,117,723
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G |
Neurog2 |
neurogenin 2 |
increases expression |
ISO |
mono-(2-ethylhexyl)phthalate results in increased expression of NEUROG2 mRNA |
CTD |
PMID:31711903 |
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NCBI chr 2:216,092,641...216,095,276
Ensembl chr 2:216,093,363...216,094,154
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G |
Nfkb1 |
nuclear factor kappa B subunit 1 |
multiple interactions increases expression |
ISO |
AKT1 protein affects the reaction [mono-(2-ethylhexyl)phthalate results in increased expression of NFKB1 mRNA] |
CTD |
PMID:18755736 |
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NCBI chr 2:224,016,214...224,132,135
Ensembl chr 2:224,016,214...224,110,404
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G |
Nfkb2 |
nuclear factor kappa B subunit 2 |
increases expression |
EXP |
mono-(2-ethylhexyl)phthalate results in increased expression of NFKB2 mRNA |
CTD |
PMID:16809437 |
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NCBI chr 1:245,164,586...245,173,225
Ensembl chr 1:245,165,950...245,173,213
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G |
Nfkbia |
NFKB inhibitor alpha |
increases expression |
EXP |
mono-(2-ethylhexyl)phthalate results in increased expression of NFKBIA mRNA |
CTD |
PMID:16809437 |
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NCBI chr 6:72,858,713...72,861,941
Ensembl chr 6:72,858,712...72,861,941
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G |
Nfkbiz |
NFKB inhibitor zeta |
increases expression |
EXP |
mono-(2-ethylhexyl)phthalate results in increased expression of NFKBIZ mRNA |
CTD |
PMID:16809437 |
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NCBI chr11:44,782,676...44,810,723
Ensembl chr11:44,782,676...44,810,723
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G |
Ngf |
nerve growth factor |
increases response to substance |
EXP |
mono-(2-ethylhexyl)phthalate results in increased susceptibility to NGF protein |
CTD |
PMID:21145954 |
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NCBI chr 2:189,901,058...189,954,452
Ensembl chr 2:189,901,058...189,954,452
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G |
Nlrp3 |
NLR family, pyrin domain containing 3 |
increases expression |
ISO |
mono-(2-ethylhexyl)phthalate results in increased expression of NLRP3 protein |
CTD |
PMID:31016965 |
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NCBI chr10:44,326,770...44,353,814
Ensembl chr10:44,328,566...44,352,811
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G |
Nme5 |
NME/NM23 family member 5 |
affects expression |
ISO |
mono-(2-ethylhexyl)phthalate affects the expression of NME5 mRNA |
CTD |
PMID:21195148 |
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NCBI chr18:26,163,558...26,180,742
Ensembl chr18:26,163,555...26,180,794
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G |
Noc4l |
nucleolar complex associated 4 homolog |
decreases expression |
ISO |
mono-(2-ethylhexyl)phthalate results in decreased expression of NOC4L mRNA |
CTD |
PMID:22401849 |
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NCBI chr12:46,016,077...46,020,615
Ensembl chr12:46,016,069...46,020,614
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G |
Nos2 |
nitric oxide synthase 2 |
multiple interactions |
ISO |
mono-(2-ethylhexyl)phthalate inhibits the reaction [[Lipopolysaccharides co-treated with IFNG protein] results in increased expression of NOS2 mRNA] |
CTD |
PMID:29718165 |
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NCBI chr10:63,815,308...63,851,208
Ensembl chr10:63,815,308...63,851,210
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G |
Npc1l1 |
NPC1 like intracellular cholesterol transporter 1 |
increases expression |
ISO |
mono-(2-ethylhexyl)phthalate results in increased expression of NPC1L1 mRNA |
CTD |
PMID:22401849 |
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NCBI chr14:81,071,448...81,091,113
Ensembl chr14:81,071,451...81,091,113
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G |
Nphp4 |
nephrocystin 4 |
increases expression |
ISO |
mono-(2-ethylhexyl)phthalate results in increased expression of NPHP4 mRNA |
CTD |
PMID:22401849 |
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NCBI chr 5:162,986,157...163,073,708
Ensembl chr 5:162,988,370...163,073,706
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G |
Nr0b1 |
nuclear receptor subfamily 0, group B, member 1 |
decreases expression multiple interactions increases expression |
EXP |
mono-(2-ethylhexyl)phthalate results in decreased expression of NR0B1 mRNA mono-(2-ethylhexyl)phthalate promotes the reaction [Tretinoin results in increased expression of NR0B1 mRNA] mono-(2-ethylhexyl)phthalate results in increased expression of NR0B1 mRNA |
CTD |
PMID:16809437 PMID:30476341 |
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NCBI chr X:50,756,886...50,761,014
Ensembl chr X:50,756,886...50,761,011
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G |
Nr1h2 |
nuclear receptor subfamily 1, group H, member 2 |
multiple interactions |
ISO |
mono-(2-ethylhexyl)phthalate promotes the reaction [NCOA1 protein binds to and results in increased activity of NR1H2 protein] |
CTD |
PMID:27551952 |
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NCBI chr 1:95,041,967...95,047,377
Ensembl chr 1:95,041,967...95,047,377
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G |
Nr1h3 |
nuclear receptor subfamily 1, group H, member 3 |
increases expression multiple interactions |
ISO |
mono-(2-ethylhexyl)phthalate results in increased expression of NR1H3 mRNA mono-(2-ethylhexyl)phthalate promotes the reaction [NCOA1 protein binds to and results in increased activity of NR1H3 protein] |
CTD |
PMID:23118965 PMID:27551952 |
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NCBI chr 3:77,158,808...77,168,907
Ensembl chr 3:77,158,808...77,168,722
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G |
Nr1h4 |
nuclear receptor subfamily 1, group H, member 4 |
decreases expression |
ISO |
mono-(2-ethylhexyl)phthalate results in decreased expression of NR1H4 mRNA |
CTD |
PMID:22401849 |
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NCBI chr 7:23,846,122...23,942,085
Ensembl chr 7:23,846,122...23,942,047
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G |
Nr1i2 |
nuclear receptor subfamily 1, group I, member 2 |
multiple interactions increases activity |
ISO |
mono-(2-ethylhexyl)phthalate binds to and results in increased activity of NR1I2 protein mono-(2-ethylhexyl)phthalate results in increased activity of NR1I2 protein |
CTD |
PMID:16054614 PMID:27551952 PMID:33049310 |
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NCBI chr11:62,460,213...62,496,665
Ensembl chr11:62,460,213...62,496,658
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G |
Nr1i3 |
nuclear receptor subfamily 1, group I, member 3 |
multiple interactions increases activity |
ISO |
[monoethyl phthalate co-treated with mono-(2-ethylhexyl)phthalate co-treated with mono-isobutyl phthalate co-treated with monoisononylphthalate co-treated with mono-benzyl phthalate] results in increased expression of NR1I3 mRNA; mono-(2-ethylhexyl)phthalate binds to and results in increased activity of NR1I3 protein; mono-(2-ethylhexyl)phthalate inhibits the reaction [Androstane-3,17-diol binds to and results in decreased activity of NR1I3 protein] mono-(2-ethylhexyl)phthalate results in increased activity of NR1I3 protein alternative form |
CTD |
PMID:18832183 PMID:27551952 PMID:31884101 |
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NCBI chr13:83,632,940...83,638,193
Ensembl chr13:83,632,899...83,637,906
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G |
Nr2f2 |
nuclear receptor subfamily 2, group F, member 2 |
multiple interactions decreases expression |
ISO |
[Genistein co-treated with mono-(2-ethylhexyl)phthalate] affects the expression of NR2F2 mRNA mono-(2-ethylhexyl)phthalate results in decreased expression of NR2F2 mRNA |
CTD |
PMID:27181934 |
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NCBI chr 1:124,008,282...124,022,521
Ensembl chr 1:124,009,181...124,022,031
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G |
Nr4a1 |
nuclear receptor subfamily 4, group A, member 1 |
increases expression decreases expression |
ISO |
mono-(2-ethylhexyl)phthalate results in increased expression of NR4A1 mRNA mono-(2-ethylhexyl)phthalate results in decreased expression of NR4A1 mRNA |
CTD |
PMID:19822197 PMID:22401849 PMID:23118965 |
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NCBI chr 7:132,368,399...132,389,300
Ensembl chr 7:132,374,840...132,389,297
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G |
Nr4a2 |
nuclear receptor subfamily 4, group A, member 2 |
increases expression |
ISO |
mono-(2-ethylhexyl)phthalate results in increased expression of NR4A2 mRNA |
CTD |
PMID:19822197 |
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NCBI chr 3:41,689,847...41,707,036
Ensembl chr 3:41,689,851...41,697,877
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G |
Nr4a3 |
nuclear receptor subfamily 4, group A, member 3 |
increases expression |
ISO |
mono-(2-ethylhexyl)phthalate results in increased expression of NR4A3 mRNA |
CTD |
PMID:19822197 |
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NCBI chr 5:62,361,588...62,401,489
Ensembl chr 5:62,361,822...62,402,733
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G |
Nr5a1 |
nuclear receptor subfamily 5, group A, member 1 |
multiple interactions |
ISO |
[Genistein co-treated with mono-(2-ethylhexyl)phthalate] results in increased expression of NR5A1 mRNA |
CTD |
PMID:27181934 |
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NCBI chr 3:22,464,786...22,486,328
Ensembl chr 3:22,465,502...22,486,328
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G |
Nrap |
nebulin-related anchoring protein |
increases expression |
ISO |
mono-(2-ethylhexyl)phthalate results in increased expression of NRAP mRNA |
CTD |
PMID:22401849 |
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NCBI chr 1:255,350,113...255,427,704
Ensembl chr 1:255,350,113...255,427,693
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G |
Nrcam |
neuronal cell adhesion molecule |
decreases expression |
ISO |
mono-(2-ethylhexyl)phthalate results in decreased expression of NRCAM mRNA |
CTD |
PMID:22401849 |
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NCBI chr 6:61,402,813...61,698,536
Ensembl chr 6:61,329,863...61,702,992
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G |
Nrep |
neuronal regeneration related protein |
affects expression |
ISO |
mono-(2-ethylhexyl)phthalate affects the expression of NREP mRNA |
CTD |
PMID:21195148 |
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NCBI chr18:25,017,069...25,046,564
Ensembl chr18:25,017,083...25,046,591
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G |
Nrf1 |
nuclear respiratory factor 1 |
affects expression |
ISO |
mono-(2-ethylhexyl)phthalate affects the expression of NRF1 mRNA |
CTD |
PMID:32522588 |
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NCBI chr 4:58,664,932...58,772,328
Ensembl chr 4:58,664,957...58,825,328
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G |
Nrg1 |
neuregulin 1 |
increases expression |
ISO |
mono-(2-ethylhexyl)phthalate results in increased expression of NRG1 mRNA |
CTD |
PMID:22401849 |
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NCBI chr16:59,250,658...60,303,024
Ensembl chr16:59,250,854...60,296,884
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G |
Nrn1 |
neuritin 1 |
decreases expression |
ISO |
mono-(2-ethylhexyl)phthalate results in decreased expression of NRN1 mRNA |
CTD |
PMID:22401849 |
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NCBI chr17:28,129,969...28,138,898
Ensembl chr17:28,129,977...28,138,896
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G |
Nsun7 |
NOP2/Sun RNA methyltransferase family member 7 |
decreases expression |
ISO |
mono-(2-ethylhexyl)phthalate results in decreased expression of NSUN7 mRNA |
CTD |
PMID:22401849 |
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NCBI chr14:41,877,500...41,935,238
Ensembl chr14:41,879,293...41,934,949
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G |
Nup210l |
nucleoporin 210-like |
decreases expression |
ISO |
mono-(2-ethylhexyl)phthalate results in decreased expression of NUP210L mRNA |
CTD |
PMID:22401849 |
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NCBI chr 2:175,545,999...175,665,332
Ensembl chr 2:175,547,988...175,665,332
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G |
Nxf2 |
nuclear RNA export factor 2 |
increases expression |
ISO |
mono-(2-ethylhexyl)phthalate results in increased expression of NXF7 mRNA |
CTD |
PMID:22401849 |
|
NCBI chr X:98,135,953...98,157,117
Ensembl chr X:98,135,950...98,157,089
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G |
Oat |
ornithine aminotransferase |
decreases expression |
ISO |
mono-(2-ethylhexyl)phthalate results in decreased expression of OAT mRNA |
CTD |
PMID:22401849 |
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NCBI chr 1:187,347,862...187,367,644
Ensembl chr 1:187,347,865...187,367,682
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G |
Ocln |
occludin |
decreases expression multiple interactions affects localization |
EXP |
mono-(2-ethylhexyl)phthalate results in decreased expression of OCLN protein [Ascorbic Acid co-treated with Vitamin E] inhibits the reaction [mono-(2-ethylhexyl)phthalate affects the localization of OCLN protein] |
CTD |
PMID:18214902 PMID:29940330 |
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NCBI chr 2:31,657,217...31,707,466
Ensembl chr 2:31,657,220...31,764,150
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G |
Odad4 |
outer dynein arm docking complex subunit 4 |
affects expression |
ISO |
mono-(2-ethylhexyl)phthalate affects the expression of ODAD4 mRNA |
CTD |
PMID:21195148 |
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NCBI chr10:85,480,089...85,508,603
Ensembl chr10:85,480,094...85,508,603
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G |
Oip5-as1 |
OIP5 antisense RNA 1 |
affects expression |
ISO |
mono-(2-ethylhexyl)phthalate affects the expression of OIP5-AS1 mRNA |
CTD |
PMID:29385630 |
|
NCBI chr 3:106,578,309...106,591,845
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G |
Otoa |
otoancorin |
increases expression |
ISO |
mono-(2-ethylhexyl)phthalate results in increased expression of OTOA mRNA |
CTD |
PMID:22401849 |
|
NCBI chr 1:175,642,978...175,710,528
Ensembl chr 1:175,642,975...175,710,435
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G |
Otog |
otogelin |
increases expression |
ISO |
mono-(2-ethylhexyl)phthalate results in increased expression of OTOG mRNA |
CTD |
PMID:22401849 |
|
NCBI chr 1:96,746,336...96,815,416
Ensembl chr 1:96,746,336...96,815,415
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G |
Oxct1 |
3-oxoacid CoA transferase 1 |
affects expression |
ISO |
mono-(2-ethylhexyl)phthalate affects the expression of OXCT1 mRNA |
CTD |
PMID:21195148 |
|
NCBI chr 2:53,236,370...53,384,715
Ensembl chr 2:53,236,368...53,384,714
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G |
Oxtr |
oxytocin receptor |
decreases expression |
ISO |
mono-(2-ethylhexyl)phthalate results in decreased expression of OXTR mRNA |
CTD |
PMID:22401849 |
|
NCBI chr 4:145,598,549...145,614,674
Ensembl chr 4:145,599,561...145,614,674
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G |
Pacs1 |
phosphofurin acidic cluster sorting protein 1 |
increases expression |
ISO |
mono-(2-ethylhexyl)phthalate results in increased expression of PACS1 mRNA |
CTD |
PMID:22401849 |
|
NCBI chr 1:202,437,503...202,569,473
Ensembl chr 1:202,437,505...202,569,473
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G |
Pah |
phenylalanine hydroxylase |
increases expression |
ISO |
mono-(2-ethylhexyl)phthalate results in increased expression of PAH mRNA |
CTD |
PMID:22401849 |
|
NCBI chr 7:21,933,179...21,998,134
Ensembl chr 7:21,933,179...21,998,130
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G |
Parvb |
parvin, beta |
decreases expression |
ISO |
mono-(2-ethylhexyl)phthalate results in decreased expression of PARVB mRNA |
CTD |
PMID:22401849 |
|
NCBI chr 7:115,360,254...115,445,767
Ensembl chr 7:115,360,261...115,445,766
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G |
Pax3 |
paired box 3 |
increases expression |
ISO |
mono-(2-ethylhexyl)phthalate results in increased expression of PAX3 mRNA |
CTD |
PMID:31711903 |
|
NCBI chr 9:79,567,455...79,664,042
Ensembl chr 9:79,568,634...79,664,042
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G |
Pax6 |
paired box 6 |
increases expression |
ISO |
mono-(2-ethylhexyl)phthalate results in increased expression of PAX6 mRNA |
CTD |
PMID:31711903 |
|
NCBI chr 3:92,128,772...92,157,022
Ensembl chr 3:92,135,637...92,157,014
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G |
Pck1 |
phosphoenolpyruvate carboxykinase 1 |
increases expression |
ISO |
mono-(2-ethylhexyl)phthalate results in increased expression of PCK1 mRNA |
CTD |
PMID:27384973 PMID:32522588 |
|
NCBI chr 3:161,930,256...161,936,205
Ensembl chr 3:161,930,256...161,936,191
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G |
Pck2 |
phosphoenolpyruvate carboxykinase 2 (mitochondrial) |
increases expression |
ISO |
mono-(2-ethylhexyl)phthalate results in increased expression of PCK2 protein |
CTD |
PMID:31228551 |
|
NCBI chr15:29,027,891...29,036,729
Ensembl chr15:29,027,894...29,037,283
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G |
Pcna |
proliferating cell nuclear antigen |
increases expression multiple interactions |
ISO |
mono-(2-ethylhexyl)phthalate results in increased expression of PCNA mRNA; mono-(2-ethylhexyl)phthalate results in increased expression of PCNA protein ESR1 protein affects the reaction [mono-(2-ethylhexyl)phthalate results in increased expression of PCNA mRNA]; MIR27B mRNA inhibits the reaction [mono-(2-ethylhexyl)phthalate results in increased expression of PCNA mRNA]; MIR27B mRNA inhibits the reaction [mono-(2-ethylhexyl)phthalate results in increased expression of PCNA protein]; MIR372 mRNA inhibits the reaction [mono-(2-ethylhexyl)phthalate results in increased expression of PCNA mRNA]; MIR372 mRNA inhibits the reaction [mono-(2-ethylhexyl)phthalate results in increased expression of PCNA protein] |
CTD |
PMID:30858031 PMID:31351048 PMID:33631300 |
|
NCBI chr 3:119,499,039...119,502,911
Ensembl chr 3:119,498,810...119,502,995
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G |
Pcolce |
procollagen C-endopeptidase enhancer |
decreases expression |
ISO |
mono-(2-ethylhexyl)phthalate results in decreased expression of PCOLCE mRNA |
CTD |
PMID:22401849 |
|
NCBI chr12:19,084,191...19,090,508
Ensembl chr12:19,084,210...19,090,508
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G |
Pcsk7 |
proprotein convertase subtilisin/kexin type 7 |
decreases expression |
ISO |
mono-(2-ethylhexyl)phthalate results in decreased expression of PCSK7 mRNA |
CTD |
PMID:22401849 |
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NCBI chr 8:46,202,079...46,224,699
Ensembl chr 8:46,202,131...46,224,705
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G |
Pcyt1a |
phosphate cytidylyltransferase 1A, choline |
decreases expression |
ISO |
mono-(2-ethylhexyl)phthalate results in decreased expression of PCYT1A mRNA |
CTD |
PMID:22401849 |
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NCBI chr11:68,313,860...68,357,828
Ensembl chr11:68,313,882...68,357,357
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G |
Pde4d |
phosphodiesterase 4D |
decreases expression |
ISO |
mono-(2-ethylhexyl)phthalate results in decreased expression of PDE4D mRNA |
CTD |
PMID:22401849 |
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NCBI chr 2:40,014,933...41,529,190
Ensembl chr 2:40,019,933...41,525,884
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G |
Pde6c |
phosphodiesterase 6C |
increases expression |
ISO |
mono-(2-ethylhexyl)phthalate results in increased expression of PDE6C mRNA |
CTD |
PMID:22401849 |
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NCBI chr 1:235,909,473...235,965,460
Ensembl chr 1:235,909,775...235,965,315
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G |
Pdilt |
protein disulfide isomerase-like, testis expressed |
increases expression |
ISO |
mono-(2-ethylhexyl)phthalate results in increased expression of PDILT mRNA |
CTD |
PMID:22401849 |
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NCBI chr 1:173,837,477...173,868,685
Ensembl chr 1:173,837,478...173,868,685
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G |
Pdk4 |
pyruvate dehydrogenase kinase 4 |
increases expression |
ISO |
mono-(2-ethylhexyl)phthalate results in increased expression of PDK4 mRNA; mono-(2-ethylhexyl)phthalate results in increased expression of PDK4 protein |
CTD |
PMID:32522588 |
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NCBI chr 4:33,591,796...33,601,798
Ensembl chr 4:33,589,799...33,601,850
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G |
Pdlim2 |
PDZ and LIM domain 2 |
decreases expression |
ISO |
mono-(2-ethylhexyl)phthalate results in decreased expression of PDLIM2 mRNA |
CTD |
PMID:22401849 |
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NCBI chr15:45,235,421...45,250,187
Ensembl chr15:45,237,477...45,249,242
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G |
Pdzrn4 |
PDZ domain containing RING finger 4 |
decreases expression |
ISO |
mono-(2-ethylhexyl)phthalate results in decreased expression of PDZRN4 mRNA |
CTD |
PMID:22401849 |
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NCBI chr 7:123,816,961...123,965,491
Ensembl chr 7:123,816,961...123,965,491
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G |
Pebp1 |
phosphatidylethanolamine binding protein 1 |
decreases expression |
EXP |
mono-(2-ethylhexyl)phthalate results in decreased expression of PBP mRNA |
CTD |
PMID:22087261 |
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NCBI chr12:39,302,864...39,307,064
Ensembl chr12:39,302,840...39,307,862
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G |
Per2 |
period circadian regulator 2 |
increases expression |
ISO |
mono-(2-ethylhexyl)phthalate results in increased expression of PER2 mRNA |
CTD |
PMID:22401849 |
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NCBI chr 9:92,007,289...92,049,551
Ensembl chr 9:92,007,296...92,049,459
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G |
Per3 |
period circadian regulator 3 |
increases expression |
ISO |
mono-(2-ethylhexyl)phthalate results in increased expression of PER3 mRNA |
CTD |
PMID:22401849 |
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NCBI chr 5:161,460,228...161,495,404
Ensembl chr 5:161,459,533...161,495,607
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G |
Pex1 |
peroxisomal biogenesis factor 1 |
decreases expression increases expression |
ISO |
mono-(2-ethylhexyl)phthalate results in decreased expression of PEX1 mRNA mono-(2-ethylhexyl)phthalate results in increased expression of PEX1 mRNA |
CTD |
PMID:22401849 PMID:32522588 |
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NCBI chr 4:30,519,950...30,558,953
Ensembl chr 4:30,519,955...30,558,921
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G |
Pex16 |
peroxisomal biogenesis factor 16 |
increases expression |
ISO |
mono-(2-ethylhexyl)phthalate results in increased expression of PEX16 mRNA |
CTD |
PMID:32522588 |
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NCBI chr 3:78,347,212...78,352,603
Ensembl chr 3:78,343,164...78,353,207
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G |
Pex19 |
peroxisomal biogenesis factor 19 |
increases expression |
ISO |
mono-(2-ethylhexyl)phthalate results in increased expression of PEX19 mRNA |
CTD |
PMID:32522588 |
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NCBI chr13:84,592,277...84,608,793
Ensembl chr13:84,592,312...84,608,608
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G |
Pgr |
progesterone receptor |
increases secretion multiple interactions |
ISO |
mono-(2-ethylhexyl)phthalate results in increased secretion of PGR protein Acetylcysteine inhibits the reaction [mono-(2-ethylhexyl)phthalate results in increased secretion of PGR protein] |
CTD |
PMID:30648648 |
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NCBI chr 8:6,073,216...6,131,552
Ensembl chr 8:6,072,673...6,131,344
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G |
Phf21b |
PHD finger protein 21B |
increases expression |
EXP |
mono-(2-ethylhexyl)phthalate results in increased expression of PHF21B mRNA |
CTD |
PMID:16809437 |
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NCBI chr 7:115,913,704...115,984,215
Ensembl chr 7:115,915,412...115,984,215
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G |
Pik3c2g |
phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 gamma |
decreases expression |
ISO |
mono-(2-ethylhexyl)phthalate results in decreased expression of PIK3C2G mRNA |
CTD |
PMID:22401849 |
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NCBI chr 4:172,483,752...172,851,623
Ensembl chr 4:172,484,345...172,850,544
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G |
Pik3r1 |
phosphoinositide-3-kinase regulatory subunit 1 |
decreases phosphorylation multiple interactions |
ISO |
mono-(2-ethylhexyl)phthalate results in decreased phosphorylation of PIK3R1 protein RBP4 protein promotes the reaction [mono-(2-ethylhexyl)phthalate results in decreased phosphorylation of PIK3R1 protein] |
CTD |
PMID:31228551 |
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NCBI chr 2:32,878,942...32,963,611
Ensembl chr 2:32,882,032...32,963,631
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G |
Piwil4 |
piwi-like RNA-mediated gene silencing 4 |
decreases expression |
ISO |
mono-(2-ethylhexyl)phthalate results in decreased expression of PIWIL4 mRNA |
CTD |
PMID:22401849 |
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NCBI chr 8:11,536,520...11,579,883
Ensembl chr 8:11,536,520...11,579,761
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G |
Pkhd1 |
PKHD1 ciliary IPT domain containing fibrocystin/polyductin |
increases expression |
ISO |
mono-(2-ethylhexyl)phthalate results in increased expression of PKHD1 mRNA |
CTD |
PMID:22401849 |
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NCBI chr 9:22,547,396...23,037,443
Ensembl chr 9:22,549,513...23,037,381
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G |
Plaat3 |
phospholipase A and acyltransferase 3 |
increases expression |
ISO |
mono-(2-ethylhexyl)phthalate results in increased expression of PLAAT3 mRNA |
CTD |
PMID:22401849 |
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NCBI chr 1:204,782,608...204,816,397
Ensembl chr 1:204,782,729...204,817,667
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G |
Plb1 |
phospholipase B1 |
decreases expression |
ISO |
mono-(2-ethylhexyl)phthalate results in decreased expression of PLB1 mRNA |
CTD |
PMID:22401849 |
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NCBI chr 6:24,087,051...24,227,167
Ensembl chr 6:24,089,214...24,210,117
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G |
Plcb2 |
phospholipase C, beta 2 |
decreases expression |
ISO |
mono-(2-ethylhexyl)phthalate results in decreased expression of PLCB2 mRNA |
CTD |
PMID:22401849 |
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NCBI chr 3:105,683,676...105,704,384
Ensembl chr 3:105,684,815...105,704,302
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G |
Pld1 |
phospholipase D1 |
increases expression |
EXP |
mono-(2-ethylhexyl)phthalate results in increased expression of PLD1 mRNA |
CTD |
PMID:16809437 |
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NCBI chr 2:110,849,205...111,047,692
Ensembl chr 2:110,893,608...111,047,692
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G |
Plin1 |
perilipin 1 |
increases expression |
ISO |
mono-(2-ethylhexyl)phthalate analog results in increased expression of PLIN1 mRNA; mono-(2-ethylhexyl)phthalate results in increased expression of PLIN1 mRNA; mono-(2-ethylhexyl)phthalate results in increased expression of PLIN1 protein |
CTD |
PMID:25777084 PMID:27384973 |
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NCBI chr 1:133,664,294...133,676,854
Ensembl chr 1:133,664,892...133,676,828
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G |
Plin2 |
perilipin 2 |
affects expression |
ISO |
mono-(2-ethylhexyl)phthalate affects the expression of PLIN2 mRNA |
CTD |
PMID:21195148 |
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NCBI chr 5:101,156,643...101,211,738
Ensembl chr 5:101,154,411...101,242,319
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G |
Plin4 |
perilipin 4 |
increases expression |
ISO |
mono-(2-ethylhexyl)phthalate results in increased expression of PLIN4 protein |
CTD |
PMID:27384973 |
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NCBI chr 9:929,168...938,062
Ensembl chr 9:929,176...938,056
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G |
Plin5 |
perilipin 5 |
decreases expression |
ISO |
mono-(2-ethylhexyl)phthalate results in decreased expression of PLIN5 mRNA |
CTD |
PMID:22401849 |
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NCBI chr 9:939,745...946,188
Ensembl chr 9:939,747...946,120
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G |
Pls1 |
plastin 1 |
affects expression |
ISO |
mono-(2-ethylhexyl)phthalate affects the expression of PLS1 mRNA |
CTD |
PMID:21195148 |
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NCBI chr 8:96,316,703...96,426,592
Ensembl chr 8:96,317,849...96,385,195
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G |
Pmaip1 |
phorbol-12-myristate-13-acetate-induced protein 1 |
increases expression |
ISO |
mono-(2-ethylhexyl)phthalate results in increased expression of PMAIP1 protein |
CTD |
PMID:24706461 |
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NCBI chr18:59,986,187...59,990,174
Ensembl chr18:59,986,017...59,992,429
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G |
Popdc3 |
popeye domain containing 3 |
decreases expression |
ISO |
mono-(2-ethylhexyl)phthalate results in decreased expression of POPDC3 mRNA |
CTD |
PMID:22401849 |
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NCBI chr20:48,772,382...48,800,364
Ensembl chr20:48,772,462...48,800,593
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G |
Pou5f1 |
POU class 5 homeobox 1 |
decreases expression |
EXP |
mono-(2-ethylhexyl)phthalate results in decreased expression of POU5F1 mRNA |
CTD |
PMID:30476341 |
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NCBI chr20:3,223,128...3,227,891
Ensembl chr20:3,223,129...3,227,891
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G |
Ppara |
peroxisome proliferator activated receptor alpha |
multiple interactions affects binding increases activity increases expression |
ISO EXP |
mono-(2-ethylhexyl)phthalate binds to and results in increased activity of PPARA protein; mono-(2-ethylhexyl)phthalate inhibits the reaction [PPARA protein binds to NCOR1 protein]; mono-(2-ethylhexyl)phthalate promotes the reaction [PPARA protein binds to EP300 protein]; mono-(2-ethylhexyl)phthalate promotes the reaction [PPARA protein binds to MED1 protein]; mono-(2-ethylhexyl)phthalate promotes the reaction [PPARA protein binds to PPARGC1A protein] mono-(2-ethylhexyl)phthalate binds to PPARA protein mono-(2-ethylhexyl)phthalate results in increased activity of PPARA protein mono-(2-ethylhexyl)phthalate results in increased expression of PPARA mRNA [monoethyl phthalate co-treated with mono-(2-ethylhexyl)phthalate co-treated with mono-isobutyl phthalate co-treated with monoisononylphthalate co-treated with mono-benzyl phthalate] results in decreased expression of PPARA mRNA; mono-(2-ethylhexyl)phthalate inhibits the reaction [PPARA protein binds to NCOR1 protein]; PPARA gene mutant form inhibits the reaction [mono-(2-ethylhexyl)phthalate results in increased expression of FGF21 mRNA]; PPARA inhibits the reaction [PPARA gene mutant form inhibits the reaction [mono-(2-ethylhexyl)phthalate results in increased expression of FGF21 mRNA]] mono-(2-ethylhexyl)phthalate results in increased expression of PPARA mRNA; mono-(2-ethylhexyl)phthalate results in increased expression of PPARA protein |
CTD |
PMID:10581215 PMID:15647598 PMID:16326050 PMID:20123618 PMID:27551952 PMID:28571686 PMID:31884101 PMID:35019730 More...
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NCBI chr 7:116,832,405...116,900,878
Ensembl chr 7:116,832,756...116,895,346
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G |
Ppard |
peroxisome proliferator-activated receptor delta |
affects expression multiple interactions increases activity affects binding |
EXP ISO |
mono-(2-ethylhexyl)phthalate affects the expression of PPARD mRNA; mono-(2-ethylhexyl)phthalate affects the expression of PPARD protein [monoethyl phthalate co-treated with mono-(2-ethylhexyl)phthalate co-treated with mono-isobutyl phthalate co-treated with monoisononylphthalate co-treated with mono-benzyl phthalate] results in increased expression of PPARD mRNA mono-(2-ethylhexyl)phthalate results in increased activity of PPARD protein mono-(2-ethylhexyl)phthalate binds to PPARB protein |
CTD |
PMID:15647598 PMID:23843199 PMID:27551952 PMID:31884101 |
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NCBI chr20:6,298,785...6,363,970
Ensembl chr20:6,298,785...6,363,968
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G |
Pparg |
peroxisome proliferator-activated receptor gamma |
multiple interactions affects expression affects activity increases activity decreases expression affects binding increases expression |
ISO EXP |
2,2-bis(4-glycidyloxyphenyl)propane inhibits the reaction [PPARG protein promotes the reaction [mono-(2-ethylhexyl)phthalate results in increased activity of CASP3 protein]]; 2-chloro-5-nitrobenzanilide inhibits the reaction [PPARG protein promotes the reaction [mono-(2-ethylhexyl)phthalate results in increased activity of CASP3 protein]]; mono-(2-ethylhexyl)phthalate binds to and affects the folding of and results in increased activity of PPARG protein; mono-(2-ethylhexyl)phthalate binds to and results in increased activity of PPARG protein; PPARG mRNA promotes the reaction [mono-(2-ethylhexyl)phthalate results in decreased expression of MMP9 protein]; PPARG mRNA promotes the reaction [mono-(2-ethylhexyl)phthalate results in increased expression of TIMP1 protein]; PPARG protein promotes the reaction [mono-(2-ethylhexyl)phthalate results in increased activity of CASP3 protein]; Rosiglitazone promotes the reaction [PPARG protein promotes the reaction [mono-(2-ethylhexyl)phthalate results in increased activity of CASP3 protein]] [monoethyl phthalate co-treated with mono-(2-ethylhexyl)phthalate co-treated with mono-isobutyl phthalate co-treated with monoisononylphthalate co-treated with mono-benzyl phthalate] results in increased expression of PPARG mRNA; mono-(2-ethylhexyl)phthalate binds to and results in increased activity of PPARG protein mono-(2-ethylhexyl)phthalate affects the expression of PPARG mRNA mono-(2-ethylhexyl)phthalate affects the activity of PPARG protein mono-(2-ethylhexyl)phthalate results in increased activity of PPARG protein mono-(2-ethylhexyl)phthalate analog results in increased activity of PPARG protein; mono-(2-ethylhexyl)phthalate results in increased activity of PPARG protein mono-(2-ethylhexyl)phthalate results in decreased expression of PPARG mRNA mono-(2-ethylhexyl)phthalate binds to PPARG protein mono-(2-ethylhexyl)phthalate results in increased expression of PPARG mRNA; mono-(2-ethylhexyl)phthalate results in increased expression of PPARG protein |
CTD |
PMID:10581215 PMID:12927354 PMID:15322177 PMID:15647598 PMID:16326050 PMID:21561829 PMID:23118965 PMID:23843199 PMID:25543134 PMID:25777084 PMID:26172262 PMID:27551952 PMID:28282128 PMID:28416457 PMID:28571686 PMID:30085373 PMID:30138673 PMID:30810372 PMID:31884101 PMID:33049310 PMID:35019730 More...
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NCBI chr 4:148,423,102...148,548,471
Ensembl chr 4:148,423,194...148,548,468
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G |
Ppargc1a |
PPARG coactivator 1 alpha |
multiple interactions increases expression |
ISO |
mono-(2-ethylhexyl)phthalate promotes the reaction [PPARA protein binds to PPARGC1A protein] mono-(2-ethylhexyl)phthalate results in increased expression of PPARGC1A mRNA |
CTD |
PMID:20123618 PMID:25543134 PMID:32522588 |
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NCBI chr14:58,860,752...59,516,525
Ensembl chr14:58,861,144...59,512,656
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G |
Ppargc1b |
PPARG coactivator 1 beta |
affects expression |
ISO |
mono-(2-ethylhexyl)phthalate affects the expression of PPARGC1B mRNA |
CTD |
PMID:32522588 |
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NCBI chr18:54,758,891...54,861,103
Ensembl chr18:54,758,902...54,861,194
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G |
Ppp1r15a |
protein phosphatase 1, regulatory subunit 15A |
increases expression |
EXP |
mono-(2-ethylhexyl)phthalate results in increased expression of PPP1R15A mRNA |
CTD |
PMID:16809437 |
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NCBI chr 1:96,000,053...96,003,128
Ensembl chr 1:96,000,058...96,003,171
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G |
Ppp1r18 |
protein phosphatase 1, regulatory subunit 18 |
affects expression |
ISO |
mono-(2-ethylhexyl)phthalate affects the expression of PPP1R18 mRNA |
CTD |
PMID:21195148 |
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NCBI chr20:2,877,567...2,887,526
Ensembl chr20:2,877,567...2,891,802
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G |
Ppp1r1a |
protein phosphatase 1, regulatory (inhibitor) subunit 1A |
affects expression |
ISO |
mono-(2-ethylhexyl)phthalate affects the expression of PPP1R1A mRNA |
CTD |
PMID:21195148 |
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NCBI chr 7:134,654,578...134,662,236
Ensembl chr 7:134,654,579...134,662,230
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G |
Prdm16 |
PR/SET domain 16 |
decreases expression |
ISO |
mono-(2-ethylhexyl)phthalate results in decreased expression of PRDM16 mRNA |
CTD |
PMID:32522588 |
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NCBI chr 5:164,879,864...165,203,986
Ensembl chr 5:164,880,587...165,203,601
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G |
Prdx2 |
peroxiredoxin 2 |
decreases expression |
EXP |
mono-(2-ethylhexyl)phthalate results in decreased expression of PRDX2 mRNA |
CTD |
PMID:22087261 |
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NCBI chr19:23,180,927...23,186,217
Ensembl chr19:23,180,930...23,186,194
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G |
Prkab2 |
protein kinase AMP-activated non-catalytic subunit beta 2 |
increases expression |
ISO |
mono-(2-ethylhexyl)phthalate results in increased expression of PRKAB2 mRNA |
CTD |
PMID:32522588 |
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NCBI chr 2:185,257,218...185,272,846
Ensembl chr 2:185,257,213...185,269,872
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G |
Prkaca |
protein kinase cAMP-activated catalytic subunit alpha |
increases expression |
ISO |
mono-(2-ethylhexyl)phthalate results in increased expression of PRKACA mRNA |
CTD |
PMID:25543134 |
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NCBI chr19:24,155,081...24,178,430
Ensembl chr19:24,155,090...24,178,430
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G |
Prkag2 |
protein kinase AMP-activated non-catalytic subunit gamma 2 |
decreases expression |
ISO |
mono-(2-ethylhexyl)phthalate results in decreased expression of PRKAG2 mRNA |
CTD |
PMID:32522588 |
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NCBI chr 4:10,010,574...10,252,152
Ensembl chr 4:10,010,890...10,252,142
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G |
Prkag3 |
protein kinase AMP-activated non-catalytic subunit gamma 3 |
increases expression |
ISO |
mono-(2-ethylhexyl)phthalate results in increased expression of PRKAG3 mRNA |
CTD |
PMID:22401849 |
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NCBI chr 9:76,295,715...76,304,959
Ensembl chr 9:76,295,715...76,304,959
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G |
Prkca |
protein kinase C, alpha |
decreases expression |
ISO |
mono-(2-ethylhexyl)phthalate results in decreased expression of PRKCA mRNA |
CTD |
PMID:22401849 |
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NCBI chr10:92,889,390...93,288,013
Ensembl chr10:92,894,012...93,288,012
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G |
Prlr |
prolactin receptor |
decreases expression |
ISO |
mono-(2-ethylhexyl)phthalate results in decreased expression of PRLR mRNA |
CTD |
PMID:22401849 |
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NCBI chr 2:59,134,147...59,324,719
Ensembl chr 2:59,134,588...59,324,718
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G |
Prnp |
prion protein |
increases expression |
ISO |
mono-(2-ethylhexyl)phthalate results in increased expression of PRNP mRNA |
CTD |
PMID:23360888 |
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NCBI chr 3:119,186,073...119,201,513
Ensembl chr 3:119,177,485...119,203,937
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G |
Prph |
peripherin |
decreases expression |
ISO |
mono-(2-ethylhexyl)phthalate results in decreased expression of PRPH mRNA |
CTD |
PMID:22401849 |
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NCBI chr 7:130,218,149...130,222,136
Ensembl chr 7:130,218,357...130,222,136
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G |
Ptch1 |
patched 1 |
multiple interactions increases expression |
ISO |
[mono-(2-ethylhexyl)phthalate co-treated with Androgens deficiency] results in increased expression of PTCH1 mRNA; mono-(2-ethylhexyl)phthalate inhibits the reaction [cyclopamine results in decreased expression of PTCH1 mRNA] mono-(2-ethylhexyl)phthalate results in increased expression of PTCH1 mRNA |
CTD |
PMID:26710974 |
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NCBI chr17:1,542,705...1,607,730
Ensembl chr17:1,542,877...1,607,333
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G |
Pten |
phosphatase and tensin homolog |
multiple interactions |
ISO |
[bisphenol A co-treated with mono-(2-ethylhexyl)phthalate] results in decreased expression of PTEN mRNA; [bisphenol A co-treated with mono-(2-ethylhexyl)phthalate] results in decreased expression of PTEN protein; [mono-(2-ethylhexyl)phthalate co-treated with bisphenol A co-treated with tubastatin A] results in increased expression of PTEN mRNA; [mono-(2-ethylhexyl)phthalate co-treated with tubastatin A] results in increased expression of PTEN mRNA; HDAC6 protein affects the reaction [[bisphenol A co-treated with mono-(2-ethylhexyl)phthalate] results in decreased expression of PTEN protein] |
CTD |
PMID:34910997 |
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NCBI chr 1:230,631,303...230,696,754
Ensembl chr 1:230,630,338...230,696,838
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G |
Ptgds |
prostaglandin D2 synthase |
multiple interactions decreases expression |
ISO |
[Genistein co-treated with mono-(2-ethylhexyl)phthalate] affects the expression of PTGDS mRNA mono-(2-ethylhexyl)phthalate results in decreased expression of PTGDS mRNA |
CTD |
PMID:34942354 |
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NCBI chr 3:8,281,899...8,284,833
Ensembl chr 3:8,281,899...8,284,833
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G |
Ptges |
prostaglandin E synthase |
multiple interactions decreases expression |
ISO |
[mono-(2-ethylhexyl)phthalate co-treated with Genistein] affects the expression of PTGES mRNA mono-(2-ethylhexyl)phthalate results in decreased expression of PTGES mRNA |
CTD |
PMID:34942354 |
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NCBI chr 3:14,177,892...14,189,236
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G |
Ptgs1 |
prostaglandin-endoperoxide synthase 1 |
multiple interactions decreases expression |
ISO |
[mono-(2-ethylhexyl)phthalate co-treated with Genistein] results in decreased expression of PTGS1 mRNA; [mono-(2-ethylhexyl)phthalate co-treated with Genistein] results in decreased expression of PTGS1 protein mono-(2-ethylhexyl)phthalate results in decreased expression of PTGS1 mRNA; mono-(2-ethylhexyl)phthalate results in decreased expression of PTGS1 protein |
CTD |
PMID:34942354 |
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NCBI chr 3:19,584,015...19,605,589
Ensembl chr 3:19,584,015...19,605,586
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G |
Ptgs2 |
prostaglandin-endoperoxide synthase 2 |
multiple interactions decreases expression increases expression |
ISO |
[mono-(2-ethylhexyl)phthalate co-treated with Genistein] results in increased expression of PTGS2 protein; Dexamethasone inhibits the reaction [mono-(2-ethylhexyl)phthalate results in increased expression of PTGS2 mRNA] mono-(2-ethylhexyl)phthalate results in decreased expression of PTGS2 mRNA mono-(2-ethylhexyl)phthalate results in increased expression of PTGS2 mRNA; mono-(2-ethylhexyl)phthalate results in increased expression of PTGS2 protein |
CTD |
PMID:9013627 PMID:23360888 PMID:29089286 PMID:34942354 |
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NCBI chr13:62,164,080...62,169,770
Ensembl chr13:62,163,932...62,172,188
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G |
Ptk2b |
protein tyrosine kinase 2 beta |
decreases expression |
ISO |
mono-(2-ethylhexyl)phthalate results in decreased expression of PTK2B mRNA |
CTD |
PMID:22401849 |
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NCBI chr15:40,360,722...40,481,235
Ensembl chr15:40,360,723...40,481,282
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G |
Ptpn18 |
protein tyrosine phosphatase, non-receptor type 18 |
increases expression |
ISO |
mono-(2-ethylhexyl)phthalate results in increased expression of PTPN18 mRNA |
CTD |
PMID:22401849 |
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NCBI chr 9:36,672,325...36,689,963
Ensembl chr 9:36,672,362...36,690,995
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G |
Ptprd |
protein tyrosine phosphatase, receptor type, D |
increases expression |
ISO |
mono-(2-ethylhexyl)phthalate results in increased expression of PTPRD mRNA |
CTD |
PMID:22401849 |
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NCBI chr 5:90,046,993...90,698,977
Ensembl chr 5:90,048,966...92,369,396
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G |
Ptprh |
protein tyrosine phosphatase, receptor type, H |
increases expression |
ISO |
mono-(2-ethylhexyl)phthalate results in increased expression of PTPRH mRNA |
CTD |
PMID:22401849 |
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NCBI chr 1:69,243,704...69,276,294
Ensembl chr 1:69,242,321...69,285,077
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G |
Pycard |
PYD and CARD domain containing |
increases expression |
ISO |
mono-(2-ethylhexyl)phthalate results in increased expression of PYCARD protein |
CTD |
PMID:31016965 |
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NCBI chr 1:182,601,657...182,603,013
Ensembl chr 1:182,601,174...182,602,955
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G |
Qrich2 |
glutamine rich 2 |
increases expression |
ISO |
mono-(2-ethylhexyl)phthalate results in increased expression of QRICH2 mRNA |
CTD |
PMID:22401849 |
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NCBI chr10:101,669,235...101,685,281 NCBI chr10:101,685,289...101,686,370 NCBI chr10:101,686,862...101,688,070 NCBI chr10:101,688,451...101,697,637
Ensembl chr10:101,669,224...101,697,656
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G |
Rab13 |
RAB13, member RAS oncogene family |
multiple interactions |
EXP |
[INS1 protein co-treated with mono-(2-ethylhexyl)phthalate] results in decreased expression of RAB13 protein |
CTD |
PMID:28526321 |
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NCBI chr 2:175,674,894...175,680,043
Ensembl chr 2:175,675,005...175,680,036
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G |
Rab20 |
RAB20, member RAS oncogene family |
increases expression |
EXP |
mono-(2-ethylhexyl)phthalate results in increased expression of RAB20 mRNA |
CTD |
PMID:16809437 |
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NCBI chr16:78,019,337...78,043,529
Ensembl chr16:78,019,337...78,043,529
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G |
Rab27a |
RAB27A, member RAS oncogene family |
decreases expression |
ISO |
mono-(2-ethylhexyl)phthalate results in decreased expression of RAB27A mRNA |
CTD |
PMID:22401849 |
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NCBI chr 8:73,782,730...73,836,630
Ensembl chr 8:73,782,694...73,847,829
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G |
Rab8a |
RAB8A, member RAS oncogene family |
multiple interactions |
EXP |
[INS1 protein co-treated with mono-(2-ethylhexyl)phthalate] results in decreased expression of RAB8A protein |
CTD |
PMID:28526321 |
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NCBI chr16:17,654,027...17,675,385
Ensembl chr16:17,654,034...17,675,678
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G |
Rabggta |
Rab geranylgeranyltransferase subunit alpha |
decreases expression |
ISO |
mono-(2-ethylhexyl)phthalate results in decreased expression of RABGGTA mRNA |
CTD |
PMID:22401849 |
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NCBI chr15:29,206,328...29,213,398
Ensembl chr15:29,206,157...29,213,348
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G |
Ranbp17 |
RAN binding protein 17 |
increases expression |
ISO |
mono-(2-ethylhexyl)phthalate results in increased expression of RANBP17 mRNA |
CTD |
PMID:22401849 |
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NCBI chr10:17,800,406...18,102,947
Ensembl chr10:17,800,999...18,102,831
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G |
Rasal1 |
RAS protein activator like 1 |
decreases expression |
ISO |
mono-(2-ethylhexyl)phthalate results in decreased expression of RASAL1 mRNA |
CTD |
PMID:22401849 |
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NCBI chr12:35,881,269...35,913,727
Ensembl chr12:35,881,270...35,913,727
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G |
Rasgef1c |
RasGEF domain family, member 1C |
increases expression |
ISO |
mono-(2-ethylhexyl)phthalate results in increased expression of RASGEF1C mRNA |
CTD |
PMID:22401849 |
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NCBI chr10:34,227,483...34,293,676
Ensembl chr10:34,227,483...34,293,675
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G |
Rasgrf2 |
RAS protein-specific guanine nucleotide-releasing factor 2 |
increases expression |
ISO |
mono-(2-ethylhexyl)phthalate results in increased expression of RASGRF2 mRNA |
CTD |
PMID:22401849 |
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NCBI chr 2:23,113,613...23,361,537
Ensembl chr 2:23,117,004...23,361,240
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G |
Rbbp7 |
RB binding protein 7, chromatin remodeling factor |
affects expression |
ISO |
mono-(2-ethylhexyl)phthalate affects the expression of RBBP7 mRNA |
CTD |
PMID:21195148 |
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NCBI chr X:31,913,080...31,931,245
Ensembl chr X:31,913,081...31,931,226
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G |
Rbm44 |
RNA binding motif protein 44 |
increases expression |
ISO |
mono-(2-ethylhexyl)phthalate results in increased expression of RBM44 mRNA |
CTD |
PMID:22401849 |
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NCBI chr 9:91,731,153...91,756,783
Ensembl chr 9:91,731,115...91,756,772
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G |
Rbmx |
RNA binding motif protein, X-linked |
affects expression |
ISO |
mono-(2-ethylhexyl)phthalate affects the expression of RBMX mRNA |
CTD |
PMID:21195148 |
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NCBI chr X:135,305,237...135,314,806
Ensembl chr X:135,305,325...135,314,743
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G |
Rbp1 |
retinol binding protein 1 |
increases expression |
EXP |
mono-(2-ethylhexyl)phthalate results in increased expression of RBP1 mRNA |
CTD |
PMID:30476341 |
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NCBI chr 8:99,025,218...99,046,740
Ensembl chr 8:99,025,206...99,046,743
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G |
Rbp4 |
retinol binding protein 4 |
multiple interactions increases expression |
ISO |
RBP4 protein promotes the reaction [[mono-(2-ethylhexyl)phthalate results in decreased activity of INS protein] which results in decreased phosphorylation of GSK3B protein]; RBP4 protein promotes the reaction [[mono-(2-ethylhexyl)phthalate results in decreased activity of INS protein] which results in decreased phosphorylation of IRS1 protein]; RBP4 protein promotes the reaction [mono-(2-ethylhexyl)phthalate inhibits the reaction [INS protein results in increased abundance of Glycogen]]; RBP4 protein promotes the reaction [mono-(2-ethylhexyl)phthalate results in decreased activity of INS protein]; RBP4 protein promotes the reaction [mono-(2-ethylhexyl)phthalate results in decreased phosphorylation of GSK3B protein]; RBP4 protein promotes the reaction [mono-(2-ethylhexyl)phthalate results in decreased phosphorylation of IRS1 protein]; RBP4 protein promotes the reaction [mono-(2-ethylhexyl)phthalate results in decreased phosphorylation of PIK3R1 protein] mono-(2-ethylhexyl)phthalate results in increased expression of RBP4 protein |
CTD |
PMID:31228551 |
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NCBI chr 1:235,893,917...235,901,315
Ensembl chr 1:235,893,917...235,901,399
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G |
Recql |
RecQ like helicase |
decreases expression |
ISO |
mono-(2-ethylhexyl)phthalate results in decreased expression of RECQL mRNA |
CTD |
PMID:22401849 |
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NCBI chr 4:175,308,337...175,332,965
Ensembl chr 4:175,304,117...175,332,945
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G |
Rela |
RELA proto-oncogene, NF-kB subunit |
increases expression multiple interactions |
ISO |
mono-(2-ethylhexyl)phthalate results in increased expression of RELA mRNA mono-(2-ethylhexyl)phthalate results in increased expression of RELA protein modified form fulvestrant inhibits the reaction [mono-(2-ethylhexyl)phthalate results in increased phosphorylation of RELA protein]; mono-(2-ethylhexyl)phthalate results in increased expression of and results in increased activity of RELA protein; mono-(2-ethylhexyl)phthalate results in increased phosphorylation of and affects the localization of RELA protein |
CTD |
PMID:28390675 PMID:31016965 |
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NCBI chr 1:202,925,001...202,935,484
Ensembl chr 1:202,924,945...202,935,484
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G |
RGD1359127 |
similar to RIKEN cDNA 2310011J03 |
affects expression |
EXP |
mono-(2-ethylhexyl)phthalate affects the expression of RGD1359127 mRNA |
CTD |
PMID:16809437 |
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NCBI chr 7:9,390,255...9,392,383
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G |
Rgs6 |
regulator of G-protein signaling 6 |
decreases expression |
ISO |
mono-(2-ethylhexyl)phthalate results in decreased expression of RGS6 mRNA |
CTD |
PMID:22401849 |
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NCBI chr 6:102,264,451...102,796,311
Ensembl chr 6:102,264,447...102,824,753
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G |
Rgs7 |
regulator of G-protein signaling 7 |
decreases expression |
ISO |
mono-(2-ethylhexyl)phthalate results in decreased expression of RGS7 mRNA |
CTD |
PMID:22401849 |
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NCBI chr13:86,979,269...87,408,834
Ensembl chr13:86,979,279...87,408,888
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G |
Rhod |
ras homolog family member D |
decreases expression |
ISO |
mono-(2-ethylhexyl)phthalate results in decreased expression of RHOD mRNA |
CTD |
PMID:22401849 |
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NCBI chr 1:201,708,699...201,724,405
Ensembl chr 1:201,708,699...201,722,632
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G |
Rimbp2 |
RIMS binding protein 2 |
increases expression |
ISO |
mono-(2-ethylhexyl)phthalate results in increased expression of RIMBP2 mRNA |
CTD |
PMID:22401849 |
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NCBI chr12:27,747,615...27,946,256
Ensembl chr12:27,747,980...27,956,763
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G |
Rims1 |
regulating synaptic membrane exocytosis 1 |
increases expression |
ISO |
mono-(2-ethylhexyl)phthalate results in increased expression of RIMS1 mRNA |
CTD |
PMID:22401849 |
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NCBI chr 9:24,696,959...25,196,368
Ensembl chr 9:24,698,854...25,196,631
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G |
Rin3 |
Ras and Rab interactor 3 |
increases expression |
EXP |
mono-(2-ethylhexyl)phthalate results in increased expression of RIN3 mRNA |
CTD |
PMID:16809437 |
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NCBI chr 6:121,431,803...121,540,957
Ensembl chr 6:121,431,339...121,540,957
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G |
Rnd1 |
Rho family GTPase 1 |
increases expression |
EXP |
mono-(2-ethylhexyl)phthalate results in increased expression of RND1 mRNA |
CTD |
PMID:16809437 |
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NCBI chr 7:129,821,311...129,828,385
Ensembl chr 7:129,821,311...129,828,399
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G |
Rnd3 |
Rho family GTPase 3 |
increases expression |
EXP |
mono-(2-ethylhexyl)phthalate results in increased expression of RND3 mRNA |
CTD |
PMID:16809437 |
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NCBI chr 3:35,571,929...35,589,283
Ensembl chr 3:35,571,143...35,589,327
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G |
Rnf123 |
ring finger protein 123 |
decreases expression |
ISO |
mono-(2-ethylhexyl)phthalate results in decreased expression of RNF123 mRNA |
CTD |
PMID:22401849 |
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NCBI chr 8:108,740,176...108,768,177
Ensembl chr 8:108,739,620...108,767,675
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G |
Rnf180 |
ring finger protein 180 |
decreases expression |
ISO |
mono-(2-ethylhexyl)phthalate results in decreased expression of RNF180 mRNA |
CTD |
PMID:22401849 |
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NCBI chr 2:36,330,285...36,511,168
Ensembl chr 2:36,330,292...36,512,614
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G |
Rora |
RAR-related orphan receptor A |
decreases expression |
ISO |
mono-(2-ethylhexyl)phthalate results in decreased expression of RORA mRNA |
CTD |
PMID:22401849 |
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NCBI chr 8:69,301,635...70,034,741
Ensembl chr 8:69,301,733...70,025,931
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G |
Rph3a |
rabphilin 3A |
increases expression |
ISO |
mono-(2-ethylhexyl)phthalate results in increased expression of RPH3A mRNA |
CTD |
PMID:22401849 |
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NCBI chr12:35,542,389...35,618,901
Ensembl chr12:35,542,728...35,617,592
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G |
Rpl23 |
ribosomal protein L23 |
affects expression |
ISO |
mono-(2-ethylhexyl)phthalate affects the expression of RPL23 mRNA |
CTD |
PMID:21195148 |
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NCBI chr10:82,771,878...82,775,840
Ensembl chr10:82,771,538...82,775,870
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G |
Rpp25 |
ribonuclease P and MRP subunit p25 |
decreases expression |
ISO |
mono-(2-ethylhexyl)phthalate results in decreased expression of RPP25 mRNA |
CTD |
PMID:22401849 |
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NCBI chr 8:57,907,352...57,908,732
Ensembl chr 8:57,907,352...57,908,732
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G |
Rrad |
RRAD, Ras related glycolysis inhibitor and calcium channel regulator |
decreases expression |
ISO |
mono-(2-ethylhexyl)phthalate results in decreased expression of RRAD mRNA |
CTD |
PMID:22401849 |
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NCBI chr19:354,184...357,424
Ensembl chr19:354,198...357,417
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G |
Rragd |
Ras-related GTP binding D |
decreases expression |
ISO |
mono-(2-ethylhexyl)phthalate results in decreased expression of RRAGD mRNA |
CTD |
PMID:22401849 |
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NCBI chr 5:47,373,902...47,409,369
Ensembl chr 5:47,373,463...47,409,356
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G |
Rsph4a |
radial spoke head component 4A |
affects expression |
ISO |
mono-(2-ethylhexyl)phthalate affects the expression of RSPH4A mRNA |
CTD |
PMID:21195148 |
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NCBI chr20:30,764,409...30,780,574
Ensembl chr20:30,764,409...30,780,574
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G |
Rsph9 |
radial spoke head component 9 |
affects expression |
ISO |
mono-(2-ethylhexyl)phthalate affects the expression of RSPH9 mRNA |
CTD |
PMID:21195148 |
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NCBI chr 9:14,839,565...14,860,062
Ensembl chr 9:14,840,115...14,860,062
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G |
Runx2 |
RUNX family transcription factor 2 |
decreases expression |
ISO |
mono-(2-ethylhexyl)phthalate results in decreased expression of RUNX2 mRNA |
CTD |
PMID:22401849 PMID:25777084 |
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NCBI chr 9:16,167,504...16,492,826
Ensembl chr 9:16,167,482...16,492,167
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G |
Rxra |
retinoid X receptor alpha |
affects binding |
ISO |
mono-(2-ethylhexyl)phthalate binds to RXRA protein |
CTD |
PMID:23843199 |
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NCBI chr 3:10,989,832...11,076,366
Ensembl chr 3:10,989,832...11,073,712
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G |
Rxrb |
retinoid X receptor beta |
affects binding |
ISO |
mono-(2-ethylhexyl)phthalate binds to RXRB protein |
CTD |
PMID:23843199 |
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NCBI chr20:4,816,813...4,823,267
Ensembl chr20:4,816,815...4,828,773
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G |
Rxrg |
retinoid X receptor gamma |
affects binding |
ISO |
mono-(2-ethylhexyl)phthalate binds to RXRG protein |
CTD |
PMID:23843199 |
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NCBI chr13:79,743,430...79,785,173
Ensembl chr13:79,743,563...79,785,167
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G |
Ryr1 |
ryanodine receptor 1 |
decreases expression |
ISO |
mono-(2-ethylhexyl)phthalate results in decreased expression of RYR1 mRNA |
CTD |
PMID:22401849 |
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NCBI chr 1:84,292,578...84,423,799
Ensembl chr 1:84,292,578...84,423,812
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G |
Scara3 |
scavenger receptor class A, member 3 |
decreases expression |
ISO |
mono-(2-ethylhexyl)phthalate results in decreased expression of SCARA3 mRNA |
CTD |
PMID:23360888 |
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NCBI chr15:40,139,873...40,172,866
Ensembl chr15:40,140,161...40,172,894
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G |
Scarb1 |
scavenger receptor class B, member 1 |
decreases expression increases expression multiple interactions |
ISO EXP |
mono-(2-ethylhexyl)phthalate results in decreased expression of SCARB1 mRNA; mono-(2-ethylhexyl)phthalate results in decreased expression of SCARB1 protein mono-(2-ethylhexyl)phthalate results in increased expression of SCARB1 mRNA [Genistein co-treated with mono-(2-ethylhexyl)phthalate] results in increased expression of SCARB1 mRNA; METTL14 protein affects the reaction [mono-(2-ethylhexyl)phthalate results in decreased expression of SCARB1 mRNA]; mono-(2-ethylhexyl)phthalate affects the reaction [METTL14 protein affects the expression of SCARB1 mRNA]; mono-(2-ethylhexyl)phthalate results in decreased expression of and results in decreased methylation of SCARB1 mRNA |
CTD |
PMID:22087261 PMID:22401849 PMID:27181934 PMID:31875672 |
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NCBI chr12:31,296,143...31,362,649
Ensembl chr12:31,296,156...31,362,647
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G |
Scd |
stearoyl-CoA desaturase |
increases expression |
ISO |
mono-(2-ethylhexyl)phthalate results in increased expression of SCD mRNA |
CTD |
PMID:23118965 |
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NCBI chr 1:243,269,745...243,282,878
Ensembl chr 1:243,269,747...243,282,562
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G |
Scg3 |
secretogranin III |
decreases expression |
ISO |
mono-(2-ethylhexyl)phthalate results in decreased expression of SCG3 mRNA |
CTD |
PMID:22401849 |
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NCBI chr 8:76,399,777...76,442,015
Ensembl chr 8:76,399,777...76,442,015
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G |
Scn1a |
sodium voltage-gated channel alpha subunit 1 |
decreases expression |
ISO |
mono-(2-ethylhexyl)phthalate results in decreased expression of SCN1A mRNA |
CTD |
PMID:22401849 |
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NCBI chr 3:50,952,790...51,071,804
Ensembl chr 3:50,952,791...51,071,699
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G |
Scn9a |
sodium voltage-gated channel alpha subunit 9 |
increases expression |
ISO |
mono-(2-ethylhexyl)phthalate results in increased expression of SCN9A mRNA |
CTD |
PMID:22401849 |
|
NCBI chr 3:51,145,148...51,293,342
Ensembl chr 3:51,145,146...51,293,516
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G |
Sec14l4 |
SEC14-like lipid binding 4 |
affects expression |
ISO |
mono-(2-ethylhexyl)phthalate affects the expression of SEC14L4 mRNA |
CTD |
PMID:21195148 |
|
NCBI chr14:78,912,750...78,928,799
Ensembl chr14:78,912,750...78,956,099
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G |
Sec62 |
SEC62 homolog, preprotein translocation factor |
decreases methylation |
ISO |
mono-(2-ethylhexyl)phthalate results in decreased methylation of SEC62 mRNA |
CTD |
PMID:31875672 |
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NCBI chr 2:112,570,810...112,607,576
Ensembl chr 2:112,570,819...112,601,814
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G |
Sema3d |
semaphorin 3D |
decreases expression |
ISO |
mono-(2-ethylhexyl)phthalate results in decreased expression of SEMA3D mRNA |
CTD |
PMID:22401849 |
|
NCBI chr 4:22,316,769...22,505,930
Ensembl chr 4:22,316,779...22,505,930
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G |
Sema4g |
semaphorin 4G |
decreases expression |
ISO |
mono-(2-ethylhexyl)phthalate results in decreased expression of SEMA4G mRNA |
CTD |
PMID:22401849 |
|
NCBI chr 1:243,849,979...243,865,343
Ensembl chr 1:243,853,854...243,865,341
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G |
Sgk1 |
serum/glucocorticoid regulated kinase 1 |
decreases expression |
ISO |
mono-(2-ethylhexyl)phthalate results in decreased expression of SGK1 mRNA |
CTD |
PMID:22401849 |
|
NCBI chr 1:22,980,257...23,098,122
Ensembl chr 1:22,980,261...23,098,283
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G |
Sgtb |
small glutamine rich tetratricopeptide repeat co-chaperone beta |
decreases expression |
ISO |
mono-(2-ethylhexyl)phthalate results in decreased expression of SGTB mRNA |
CTD |
PMID:22401849 |
|
NCBI chr 2:35,233,045...35,269,527
Ensembl chr 2:35,233,042...35,269,518
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G |
Sh3bgr |
SH3 domain binding glutamate-rich protein |
decreases expression |
ISO |
mono-(2-ethylhexyl)phthalate results in decreased expression of SH3BGR mRNA |
CTD |
PMID:22401849 |
|
NCBI chr11:35,503,663...35,527,853
Ensembl chr11:35,503,725...35,527,853
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G |
Sh3rf1 |
SH3 domain containing ring finger 1 |
increases expression |
EXP |
mono-(2-ethylhexyl)phthalate results in increased expression of SH3RF1 mRNA |
CTD |
PMID:16809437 |
|
NCBI chr16:28,735,522...28,901,690
Ensembl chr16:28,735,440...28,901,644
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G |
Shbg |
sex hormone binding globulin |
decreases secretion |
ISO |
mono-(2-ethylhexyl)phthalate results in decreased secretion of SHBG protein |
CTD |
PMID:24945889 |
|
NCBI chr10:54,332,939...54,350,409
Ensembl chr10:54,332,941...54,351,057
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G |
Shkbp1 |
Sh3kbp1 binding protein 1 |
decreases expression |
ISO |
mono-(2-ethylhexyl)phthalate results in decreased expression of SHKBP1 mRNA |
CTD |
PMID:22401849 |
|
NCBI chr 1:82,636,797...82,650,330
Ensembl chr 1:82,636,797...82,650,375
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G |
Si |
sucrase-isomaltase |
decreases expression |
ISO |
mono-(2-ethylhexyl)phthalate results in decreased expression of SIS mRNA |
CTD |
PMID:22401849 |
|
NCBI chr 2:157,505,893...157,586,228
Ensembl chr 2:157,506,342...157,585,260
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G |
Sirt1 |
sirtuin 1 |
decreases expression |
ISO |
mono-(2-ethylhexyl)phthalate results in decreased expression of SIRT1 mRNA; mono-(2-ethylhexyl)phthalate results in decreased expression of SIRT1 protein |
CTD |
PMID:31016965 |
|
NCBI chr20:25,307,143...25,329,260
Ensembl chr20:25,306,917...25,329,260
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G |
Sirt2 |
sirtuin 2 |
decreases expression |
ISO |
mono-(2-ethylhexyl)phthalate results in decreased expression of SIRT2 mRNA; mono-(2-ethylhexyl)phthalate results in decreased expression of SIRT2 protein |
CTD |
PMID:31016965 |
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NCBI chr 1:84,053,883...84,076,975
Ensembl chr 1:84,052,903...84,076,975
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G |
Sirt3 |
sirtuin 3 |
increases expression decreases expression |
ISO |
mono-(2-ethylhexyl)phthalate results in increased expression of SIRT3 mRNA mono-(2-ethylhexyl)phthalate results in decreased expression of SIRT3 mRNA; mono-(2-ethylhexyl)phthalate results in decreased expression of SIRT3 protein |
CTD |
PMID:25543134 PMID:31016965 PMID:32522588 |
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NCBI chr 1:195,942,066...195,964,472
Ensembl chr 1:195,942,073...195,964,808
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G |
Sirt4 |
sirtuin 4 |
decreases expression |
ISO |
mono-(2-ethylhexyl)phthalate results in decreased expression of SIRT4 mRNA; mono-(2-ethylhexyl)phthalate results in decreased expression of SIRT4 protein |
CTD |
PMID:31016965 |
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NCBI chr12:41,125,533...41,139,440
Ensembl chr12:41,131,262...41,139,439
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G |
Sirt5 |
sirtuin 5 |
decreases expression |
ISO |
mono-(2-ethylhexyl)phthalate results in decreased expression of SIRT5 mRNA; mono-(2-ethylhexyl)phthalate results in decreased expression of SIRT5 protein |
CTD |
PMID:31016965 |
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NCBI chr17:21,310,028...21,337,137
Ensembl chr17:21,310,028...21,337,101
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G |
Sirt6 |
sirtuin 6 |
decreases expression |
ISO |
mono-(2-ethylhexyl)phthalate results in decreased expression of SIRT6 mRNA; mono-(2-ethylhexyl)phthalate results in decreased expression of SIRT6 protein |
CTD |
PMID:31016965 |
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NCBI chr 7:8,082,312...8,087,776
Ensembl chr 7:8,082,364...8,098,914
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G |
Sirt7 |
sirtuin 7 |
decreases expression |
ISO |
mono-(2-ethylhexyl)phthalate results in decreased expression of SIRT7 mRNA; mono-(2-ethylhexyl)phthalate results in decreased expression of SIRT7 protein |
CTD |
PMID:31016965 |
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NCBI chr10:105,896,476...105,903,301
Ensembl chr10:105,896,476...105,903,172
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G |
Six2 |
SIX homeobox 2 |
affects expression |
ISO |
mono-(2-ethylhexyl)phthalate affects the expression of SIX2 mRNA |
CTD |
PMID:21195148 |
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NCBI chr 6:8,974,859...8,981,345
Ensembl chr 6:8,967,157...8,981,193
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G |
Skp2 |
S-phase kinase associated protein 2 |
multiple interactions |
ISO |
[monoethyl phthalate co-treated with mono-(2-ethylhexyl)phthalate co-treated with mono-isobutyl phthalate co-treated with monoisononylphthalate co-treated with mono-benzyl phthalate] results in decreased expression of SKP2 mRNA |
CTD |
PMID:31884101 |
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NCBI chr 2:58,161,226...58,189,293
Ensembl chr 2:58,161,229...58,189,338
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G |
Slc10a7 |
solute carrier family 10, member 7 |
decreases expression |
ISO |
mono-(2-ethylhexyl)phthalate results in decreased expression of SLC10A7 mRNA |
CTD |
PMID:22401849 |
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NCBI chr19:29,183,143...29,407,470
Ensembl chr19:29,183,155...29,407,464
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