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ONTOLOGY REPORT - ANNOTATIONS


Term:2-deoxy-D-glucose
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Accession:CHEBI:15866 term browser browse the term
Definition:A deoxyglucose that is D-glucose in which the hydroxy group at position 2 has been replaced by a hydrogen. It is an antimetabolite of glucose with antiviral activity, which acts by inhibiting the glycosylation of glycoproteins and glycolipids. Used as an antiherpes agent.
Synonyms:related_synonym: 2-Deoxy-D-arabino-hexose;   2-Deoxy-D-mannose;   D-2dGlc;   D-arabino-2-Deoxyhexose;   Deoxyglucose;   Formula=C6H12O5
 alt_id: CHEBI:1078;   CHEBI:11565;   CHEBI:11569;   CHEBI:19553;   CHEBI:57546
 xref: CAS:154-17-6 "KEGG COMPOUND";   KEGG:C00586
 xref_mesh: MESH:D003847
 xref: MetaCyc:2-DEOXY-D-GLUCOSE;   Wikipedia:2-Deoxy-D-glucose


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2-deoxy-D-glucose term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G A2m alpha-2-macroglobulin JBrowse link 6 121,636,165 121,679,238 RGD:6480464
G Abcb1a ATP-binding cassette, sub-family B (MDR/TAP), member 1A JBrowse link 5 8,567,091 8,748,575 RGD:6480464
G Abcc9 ATP-binding cassette, sub-family C (CFTR/MRP), member 9 JBrowse link 6 142,587,862 142,702,766 RGD:6480464
G Abra actin-binding Rho activating protein JBrowse link 15 41,865,293 41,869,720 RGD:6480464
G Adipoq adiponectin, C1Q and collagen domain containing JBrowse link 16 23,146,536 23,157,968 RGD:6480464
G Agrp agouti related neuropeptide JBrowse link 8 105,566,695 105,579,845 RGD:6480464
G App amyloid beta (A4) precursor protein JBrowse link 16 84,952,666 85,175,255 RGD:6480464
G Atg3 autophagy related 3 JBrowse link 16 45,158,829 45,188,538 RGD:6480464
G Atg4b autophagy related 4B, cysteine peptidase JBrowse link 1 93,754,905 93,789,606 RGD:6480464
G Atg7 autophagy related 7 JBrowse link 6 114,643,097 114,860,614 RGD:6480464
G Bax BCL2-associated X protein JBrowse link 7 45,461,695 45,466,903 RGD:6480464
G Bcl2 B cell leukemia/lymphoma 2 JBrowse link 1 106,538,176 106,714,290 RGD:6480464
G Bcl2l1 BCL2-like 1 JBrowse link 2 152,758,732 152,833,803 RGD:6480464
G Becn1 beclin 1, autophagy related JBrowse link 11 101,288,258 101,302,286 RGD:6480464
G Bid BH3 interacting domain death agonist JBrowse link 6 120,893,119 120,917,062 RGD:6480464
G Casp3 caspase 3 JBrowse link 8 46,617,291 46,639,698 RGD:6480464
G Casp9 caspase 9 JBrowse link 4 141,793,612 141,815,978 RGD:6480464
G Cdkn1a cyclin-dependent kinase inhibitor 1A (P21) JBrowse link 17 29,090,979 29,100,722 RGD:6480464
G Chrm3 cholinergic receptor, muscarinic 3, cardiac JBrowse link 13 9,875,486 10,361,062 RGD:6480464
G Chuk conserved helix-loop-helix ubiquitous kinase JBrowse link 19 44,073,334 44,107,505 RGD:6480464
G Ctsd cathepsin D JBrowse link 7 142,375,910 142,387,827 RGD:6480464
G Cul7 cullin 7 JBrowse link 17 46,650,338 46,664,364 RGD:6480464
G Ddit3 DNA-damage inducible transcript 3 JBrowse link 10 127,290,793 127,296,291 RGD:6480464
G Egfr epidermal growth factor receptor JBrowse link 11 16,752,203 16,913,907 RGD:6480464
G Eif4ebp1 eukaryotic translation initiation factor 4E binding protein 1 JBrowse link 8 27,260,327 27,275,656 RGD:6480464
G Erbb2 erb-b2 receptor tyrosine kinase 2 JBrowse link 11 98,412,484 98,437,716 RGD:6480464
G Fxyd2 FXYD domain-containing ion transport regulator 2 JBrowse link 9 45,399,709 45,410,278 RGD:6480464
G Galr1 galanin receptor 1 JBrowse link 18 82,392,496 82,406,777 RGD:6480464
G Gcg glucagon JBrowse link 2 62,474,530 62,483,653 RGD:6480464
G Gpx4 glutathione peroxidase 4 JBrowse link 10 80,047,166 80,056,439 RGD:6480464
G Gsk3b glycogen synthase kinase 3 beta JBrowse link 16 38,089,001 38,246,084 RGD:6480464
G H2ax H2A.X variant histone JBrowse link 9 44,334,715 44,336,077 RGD:6480464
G Hmox1 heme oxygenase 1 JBrowse link 8 75,093,618 75,100,593 RGD:6480464
G Hsp90aa1 heat shock protein 90, alpha (cytosolic), class A member 1 JBrowse link 12 110,691,036 110,696,395 RGD:6480464
G Hsp90b1 heat shock protein 90, beta (Grp94), member 1 JBrowse link 10 86,690,841 86,705,444 RGD:6480464
G Hspa5 heat shock protein 5 JBrowse link 2 34,772,090 34,776,529 RGD:6480464
G Htra2 HtrA serine peptidase 2 JBrowse link 6 83,051,266 83,054,571 RGD:6480464
G Igf1r insulin-like growth factor I receptor JBrowse link 7 67,952,257 68,233,668 RGD:6480464
G Il1b interleukin 1 beta JBrowse link 2 129,364,569 129,371,164 RGD:6480464
G Ins1 insulin I JBrowse link 19 52,264,297 52,265,015 RGD:6480464
G Ins2 insulin II JBrowse link 7 142,678,656 142,679,726 RGD:6480464
G Itgb1 integrin beta 1 (fibronectin receptor beta) JBrowse link 8 128,685,654 128,733,579 RGD:6480464
G Kcnh2 potassium voltage-gated channel, subfamily H (eag-related), member 2 JBrowse link 5 24,319,589 24,351,684 RGD:6480464
G Kcnj11 potassium inwardly rectifying channel, subfamily J, member 11 JBrowse link 7 46,097,123 46,100,952 RGD:6480464
G Lep leptin JBrowse link 6 29,060,221 29,073,876 RGD:6480464
G Map1lc3a microtubule-associated protein 1 light chain 3 alpha JBrowse link 2 155,276,364 155,278,073 RGD:6480464
G Map1lc3b microtubule-associated protein 1 light chain 3 beta JBrowse link 8 121,590,438 121,598,760 RGD:6480464
G Mapk1 mitogen-activated protein kinase 1 JBrowse link 16 16,983,382 17,047,453 RGD:6480464
G Mapk3 mitogen-activated protein kinase 3 JBrowse link 7 126,759,626 126,765,816 RGD:6480464
G Metrnl meteorin, glial cell differentiation regulator-like JBrowse link 11 121,702,427 121,717,389 RGD:6480464
G Mmp13 matrix metallopeptidase 13 JBrowse link 9 7,272,514 7,283,333 RGD:6480464
G Mmp9 matrix metallopeptidase 9 JBrowse link 2 164,940,326 164,955,850 RGD:6480464
G Mtor mechanistic target of rapamycin kinase JBrowse link 4 148,448,582 148,557,685 RGD:6480464
G Nfkb1 nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105 JBrowse link 3 135,584,655 135,691,969 RGD:6480464
G Nos2 nitric oxide synthase 2, inducible JBrowse link 11 78,920,787 78,960,226 RGD:6480464
G Npy neuropeptide Y JBrowse link 6 49,822,710 49,829,507 RGD:6480464
G Oat ornithine aminotransferase JBrowse link 7 132,557,475 132,576,398 RGD:6480464
G Parp1 poly (ADP-ribose) polymerase family, member 1 JBrowse link 1 180,568,891 180,600,999 RGD:6480464
G Pmch pro-melanin-concentrating hormone JBrowse link 10 88,091,072 88,092,374 RGD:6480464
G Ppara peroxisome proliferator activated receptor alpha JBrowse link 15 85,734,910 85,806,851 RGD:6480464
G Pparg peroxisome proliferator activated receptor gamma JBrowse link 6 115,360,879 115,490,404 RGD:6480464
G Ppp3ca protein phosphatase 3, catalytic subunit, alpha isoform JBrowse link 3 136,669,714 136,937,727 RGD:6480464
G Raf1 v-raf-leukemia viral oncogene 1 JBrowse link 6 115,618,569 115,676,635 RGD:6480464
G Rps6 ribosomal protein S6 JBrowse link 4 86,854,099 86,857,367 RGD:6480464
G Rps6kb1 ribosomal protein S6 kinase, polypeptide 1 JBrowse link 11 86,498,869 86,544,885 RGD:6480464
G Serpinb5 serine (or cysteine) peptidase inhibitor, clade B, member 5 JBrowse link 1 106,861,175 106,883,348 RGD:6480464
G Slc2a1 solute carrier family 2 (facilitated glucose transporter), member 1 JBrowse link 4 119,108,745 119,137,330 RGD:6480464
G Slc2a2 solute carrier family 2 (facilitated glucose transporter), member 2 JBrowse link 3 28,697,903 28,728,361 RGD:6480464
G Slc2a3 solute carrier family 2 (facilitated glucose transporter), member 3 JBrowse link 6 122,727,809 122,802,363 RGD:6480464
G Slc2a4 solute carrier family 2 (facilitated glucose transporter), member 4 JBrowse link 11 69,942,286 69,948,216 RGD:6480464
G Slc2a8 solute carrier family 2, (facilitated glucose transporter), member 8 JBrowse link 2 32,972,981 32,982,083 RGD:6480464
G Sod2 superoxide dismutase 2, mitochondrial JBrowse link 17 13,007,839 13,018,119 RGD:6480464
G Sqstm1 sequestosome 1 JBrowse link 11 50,200,152 50,210,820 RGD:6480464
G Srebf1 sterol regulatory element binding transcription factor 1 JBrowse link 11 60,199,084 60,224,186 RGD:6480464
G Stk11 serine/threonine kinase 11 JBrowse link 10 80,115,767 80,130,679 RGD:6480464
G Tnf tumor necrosis factor JBrowse link 17 35,199,367 35,202,007 RGD:6480464
G Trp53 transformation related protein 53 JBrowse link 11 69,580,348 69,591,873 RGD:6480464
G Xiap X-linked inhibitor of apoptosis JBrowse link X 42,059,613 42,109,664 RGD:6480464

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 20971
    role 20952
      biological role 20950
        biochemical role 19959
          metabolite 19886
            fundamental metabolite 9552
              glucose 2071
                D-glucose 2071
                  2-deoxy-D-glucose 78
                    2-deoxy-D-glucopyranose 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 20971
    subatomic particle 20965
      composite particle 20965
        hadron 20965
          baryon 20965
            nucleon 20965
              atomic nucleus 20965
                atom 20965
                  main group element atom 20803
                    p-block element atom 20803
                      carbon group element atom 20543
                        carbon atom 20519
                          organic molecular entity 20519
                            heteroorganic entity 20159
                              organochalcogen compound 19596
                                organooxygen compound 19535
                                  carbohydrates and carbohydrate derivatives 12647
                                    carbohydrate 12647
                                      monosaccharide 3988
                                        aldose 2473
                                          aldohexose 2112
                                            glucose 2071
                                              D-glucose 2071
                                                D-glucopyranose 1634
                                                  2-deoxy-D-glucose 78
                                                    2-deoxy-D-glucopyranose 0
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.