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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:ethylamine
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Accession:CHEBI:15862 term browser browse the term
Definition:A two-carbon primary aliphatic amine.
Synonyms:related_synonym: 1-aminoethane;   ETHANAMINE;   Formula=C2H7N;   InChI=1S/C2H7N/c1-2-3/h2-3H2,1H3;   InChIKey=QUSNBJAOOMFDIB-UHFFFAOYSA-N;   SMILES=CCN;   aminoethane
 alt_id: CHEBI:14228;   CHEBI:23998;   CHEBI:44361;   CHEBI:4897
 xref: Beilstein:505933;   CAS:75-04-7;   Gmelin:897;   HMDB:HMDB0013231;   KEGG:C00797
 xref_mesh: MESH:C041564
 xref: MetaCyc:ETHANAMINE;   PDBeChem:NEH;   PMID:10930630;   PMID:11074065;   Reaxys:505933;   Wikipedia:Ethylamine
 cyclic_relationship: is_conjugate_base_of CHEBI:566789


show annotations for term's descendants           Sort by:
ethylamine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G INS insulin multiple interactions ISO [1-Methyl-3-isobutylxanthine co-treated with butylbenzyl phthalate co-treated with INS protein] results in increased abundance of ethylamine analog CTD PMID:26820058 NCBI chr11:2,159,779...2,161,209
Ensembl chr11:2,159,779...2,161,221 		JBrowse link
amifostine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BAX BCL2 associated X, apoptosis regulator multiple interactions EXP [Amifostine co-treated with Doxorubicin] results in increased expression of BAX mRNA CTD PMID:15985719 NCBI chr19:48,954,875...48,961,798
Ensembl chr19:48,954,815...48,961,798 		JBrowse link
G BCL2 BCL2 apoptosis regulator multiple interactions EXP [Amifostine co-treated with Doxorubicin] results in decreased expression of BCL2 mRNA CTD PMID:15985719 NCBI chr18:63,123,346...63,320,090
Ensembl chr18:63,123,346...63,320,128 		JBrowse link
G CASP3 caspase 3 multiple interactions EXP [Amifostine co-treated with Doxorubicin] results in increased activity of CASP3 protein; Amifostine inhibits the reaction [Idarubicin results in increased activity of CASP3 protein]; Amifostine promotes the reaction [Idarubicin results in increased activity of CASP3 protein] CTD PMID:15985719 PMID:18438337 NCBI chr 4:184,627,696...184,649,447
Ensembl chr 4:184,627,696...184,650,062 		JBrowse link
G CDK1 cyclin dependent kinase 1 decreases phosphorylation
multiple interactions		 EXP Amifostine results in decreased phosphorylation of CDK1 protein
olomoucine inhibits the reaction [TP53 protein promotes the reaction [Amifostine results in decreased phosphorylation of CDK1 protein]]; TP53 protein promotes the reaction [Amifostine results in decreased phosphorylation of CDK1 protein]		 CTD PMID:16628227 NCBI chr10:60,778,331...60,794,852
Ensembl chr10:60,778,331...60,794,852 		JBrowse link
G CDKN1A cyclin dependent kinase inhibitor 1A decreases expression
increases expression		 EXP Amifostine results in decreased expression of CDKN1A mRNA
Amifostine results in increased expression of CDKN1A protein		 CTD PMID:12618886 PMID:14555708 NCBI chr 6:36,676,463...36,687,332
Ensembl chr 6:36,676,460...36,687,337 		JBrowse link
G EI24 EI24 autophagy associated transmembrane protein decreases expression EXP Amifostine results in decreased expression of EI24 mRNA CTD PMID:14555708 NCBI chr11:125,569,477...125,584,684
Ensembl chr11:125,569,280...125,584,684 		JBrowse link
G IL6 interleukin 6 multiple interactions ISO Amifostine inhibits the reaction [IL6 protein results in increased phosphorylation of MYL2 protein] CTD PMID:19010997 NCBI chr 7:22,727,200...22,731,998
Ensembl chr 7:22,725,884...22,732,002 		JBrowse link
G MAPK14 mitogen-activated protein kinase 14 multiple interactions ISO Amifostine inhibits the reaction [Lipopolysaccharides results in increased activity of and results in increased phosphorylation of MAPK14 protein] CTD PMID:19010997 NCBI chr 6:36,027,808...36,124,214
Ensembl chr 6:36,027,782...36,111,236 		JBrowse link
G MDM2 MDM2 proto-oncogene decreases expression EXP Amifostine results in decreased expression of MDM2 mRNA CTD PMID:14555708 NCBI chr12:68,808,172...68,850,686
Ensembl chr12:68,808,177...68,845,544 		JBrowse link
G MPO myeloperoxidase multiple interactions ISO Amifostine inhibits the reaction [Lipopolysaccharides results in increased activity of MPO protein] CTD PMID:19010997 NCBI chr17:58,269,855...58,280,935
Ensembl chr17:58,269,855...58,280,935 		JBrowse link
G MYC MYC proto-oncogene, bHLH transcription factor multiple interactions EXP [Amifostine co-treated with TP53] results in increased expression of MYC mRNA CTD PMID:14555708 NCBI chr 8:127,735,434...127,742,951
Ensembl chr 8:127,735,434...127,742,951 		JBrowse link
G MYL2 myosin light chain 2 multiple interactions EXP
ISO		 Amifostine inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MYL2 protein]
Amifostine inhibits the reaction [Hydrogen Peroxide results in increased phosphorylation of MYL2 protein]; Amifostine inhibits the reaction [IL6 protein results in increased phosphorylation of MYL2 protein]		 CTD PMID:19010997 NCBI chr12:110,910,845...110,921,449
Ensembl chr12:110,910,819...110,921,443 		JBrowse link
G NFKBIA NFKB inhibitor alpha decreases expression
multiple interactions		 ISO
EXP		 Amifostine results in decreased expression of NFKBIA protein
Amifostine inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of NFKBIA protein]		 CTD PMID:10590050 PMID:19010997 NCBI chr14:35,401,513...35,404,749
Ensembl chr14:35,401,079...35,404,749 		JBrowse link
G PCNA proliferating cell nuclear antigen multiple interactions ISO Amifostine inhibits the reaction [Benzene results in decreased expression of PCNA protein] CTD PMID:17661222 NCBI chr20:5,114,953...5,126,622
Ensembl chr20:5,114,953...5,126,626 		JBrowse link
G RELA RELA proto-oncogene, NF-kB subunit multiple interactions
increases localization		 EXP Amifostine inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of RELA protein]
Amifostine results in increased localization of RELA protein		 CTD PMID:10590050 PMID:19010997 NCBI chr11:65,653,601...65,663,857
Ensembl chr11:65,653,599...65,663,090 		JBrowse link
G TP53 tumor protein p53 multiple interactions
increases expression
affects response to substance
increases activity		 EXP [Amifostine co-treated with TP53] results in increased expression of MYC mRNA; olomoucine inhibits the reaction [TP53 protein promotes the reaction [Amifostine results in decreased phosphorylation of CDK1 protein]]; TP53 protein promotes the reaction [Amifostine results in decreased phosphorylation of CDK1 protein]
Amifostine results in increased expression of TP53 protein
TP53 affects the susceptibility to Amifostine
Amifostine results in increased activity of TP53 protein		 CTD PMID:12618886 PMID:14555708 PMID:16628227 NCBI chr17:7,668,421...7,687,490
Ensembl chr17:7,661,779...7,687,538 		JBrowse link
G TP53I3 tumor protein p53 inducible protein 3 decreases expression EXP Amifostine results in decreased expression of TP53I3 mRNA CTD PMID:14555708 NCBI chr 2:24,077,433...24,084,834
Ensembl chr 2:24,077,433...24,085,861 		JBrowse link
cystamine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACTA2 actin alpha 2, smooth muscle multiple interactions ISO Cystamine inhibits the reaction [Carbon Tetrachloride results in increased expression of ACTA2 mRNA]; Cystamine inhibits the reaction [Carbon Tetrachloride results in increased expression of ACTA2 protein] CTD PMID:17708605 NCBI chr10:88,935,074...88,991,337
Ensembl chr10:88,935,074...88,991,339 		JBrowse link
G COL1A1 collagen type I alpha 1 chain multiple interactions ISO Cystamine inhibits the reaction [Carbon Tetrachloride results in increased expression of COL1A1 mRNA] CTD PMID:17708605 NCBI chr17:50,184,101...50,201,631
Ensembl chr17:50,184,101...50,201,632 		JBrowse link
G TGM2 transglutaminase 2 multiple interactions ISO Cystamine inhibits the reaction [Carbon Tetrachloride results in increased expression of TGM2 mRNA]; Cystamine inhibits the reaction [Carbon Tetrachloride results in increased expression of TGM2 protein] CTD PMID:17708605 NCBI chr20:38,127,385...38,168,475
Ensembl chr20:38,127,385...38,166,578 		JBrowse link
G TIMP1 TIMP metallopeptidase inhibitor 1 multiple interactions ISO Cystamine inhibits the reaction [Carbon Tetrachloride results in increased expression of TIMP1 mRNA] CTD PMID:17708605 NCBI chr  X:47,582,436...47,586,789
Ensembl chr  X:47,582,408...47,586,789 		JBrowse link
cysteamine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADIPOR2 adiponectin receptor 2 increases expression ISO dietary cysteamine increases expression of adipor2 mRNA in soleus muscle and retroperitoneal adipose tissue RGD PMID:17696487 RGD:21079417 NCBI chr12:1,691,070...1,788,674
Ensembl chr12:1,688,574...1,788,674 		JBrowse link
G CTSD cathepsin D increases expression
multiple interactions		 ISO Cysteamine results in increased expression of CTSD protein
Omeprazole inhibits the reaction [Cysteamine results in increased expression of CTSD protein]; thamira parpam inhibits the reaction [Cysteamine results in increased expression of CTSD protein]		 CTD PMID:20165931 NCBI chr11:1,752,755...1,763,927
Ensembl chr11:1,752,752...1,764,573 		JBrowse link
G CYP7A1 cytochrome P450 family 7 subfamily A member 1 increases activity ISO Cysteamine results in increased activity of CYP7A1 protein CTD PMID:1175606 NCBI chr 8:58,490,178...58,500,163
Ensembl chr 8:58,490,178...58,500,163 		JBrowse link
G GCLC glutamate-cysteine ligase catalytic subunit decreases activity
multiple interactions		 ISO Cysteamine results in decreased activity of GCLC protein
[Cysteamine results in decreased activity of GCLC protein] which results in decreased abundance of Glutathione		 CTD PMID:15282320 NCBI chr 6:53,497,341...53,545,101
Ensembl chr 6:53,497,341...53,616,970 		JBrowse link
G GHRL ghrelin and obestatin prepropeptide decreases expression
multiple interactions		 ISO Cysteamine results in decreased expression of GHRL mRNA; Cysteamine results in decreased expression of GHRL protein
Cysteamine results in increased expression of and results in increased secretion of GHRL protein		 CTD PMID:15778430 NCBI chr 3:10,285,666...10,292,947
Ensembl chr 3:10,285,666...10,292,947 		JBrowse link
G HMOX1 heme oxygenase 1 increases expression
multiple interactions		 ISO [Cysteamine results in increased expression of HMOX1] which results in increased expression of SOD2; Cysteamine results in increased expression of HMOX1 mRNA; Cysteamine results in increased expression of HMOX1 protein
[stannous mesoporphyrin results in decreased activity of HMOX1 protein] inhibits the reaction [Cysteamine results in increased expression of SOD2 protein]		 CTD PMID:10942521 NCBI chr22:35,381,096...35,394,207
Ensembl chr22:35,380,361...35,394,214 		JBrowse link
G MMP12 matrix metallopeptidase 12 increases expression EXP Cysteamine results in increased expression of MMP12 mRNA; Cysteamine results in increased expression of MMP12 protein CTD PMID:22532830 NCBI chr11:102,862,736...102,874,982
Ensembl chr11:102,862,736...102,874,982 		JBrowse link
G MMP14 matrix metallopeptidase 14 increases expression EXP Cysteamine results in increased expression of MMP14 mRNA; Cysteamine results in increased expression of MMP14 protein CTD PMID:22532830 NCBI chr14:22,836,585...22,847,758
Ensembl chr14:22,836,560...22,849,041 		JBrowse link
G MMP9 matrix metallopeptidase 9 decreases activity
multiple interactions
increases expression		 EXP Cysteamine results in decreased activity of MMP9 protein
Cysteamine results in increased expression of and results in decreased activity of MMP9 protein
Cysteamine results in increased expression of MMP9 mRNA		 CTD PMID:22532830 NCBI chr20:46,008,908...46,016,561
Ensembl chr20:46,008,908...46,016,561 		JBrowse link
G MPO myeloperoxidase multiple interactions
increases expression		 ISO geraniol inhibits the reaction [Cysteamine results in increased expression of MPO protein]; Omeprazole inhibits the reaction [Cysteamine results in increased expression of MPO protein]; thamira parpam inhibits the reaction [Cysteamine results in increased expression of MPO protein] CTD PMID:20165931 PMID:24337826 NCBI chr17:58,269,855...58,280,935
Ensembl chr17:58,269,855...58,280,935 		JBrowse link
G SOD2 superoxide dismutase 2 increases expression
multiple interactions		 ISO [Cysteamine results in increased expression of HMOX1] which results in increased expression of SOD2; Cysteamine results in increased expression of SOD2 mRNA; Cysteamine results in increased expression of SOD2 protein
[stannous mesoporphyrin results in decreased activity of HMOX1 protein] inhibits the reaction [Cysteamine results in increased expression of SOD2 protein]		 CTD PMID:10942521 NCBI chr 6:159,669,069...159,762,281
Ensembl chr 6:159,669,069...159,762,529 		JBrowse link
G SST somatostatin decreases expression ISO Cysteamine results in decreased expression of SST protein CTD PMID:15778430 NCBI chr 3:187,668,912...187,670,394
Ensembl chr 3:187,668,912...187,670,394 		JBrowse link
G VNN1 vanin 1 increases chemical synthesis
multiple interactions		 ISO VNN1 results in increased chemical synthesis of Cysteamine
Cysteamine inhibits the reaction [VNN1 gene mutant form results in decreased susceptibility to Paraquat]		 CTD PMID:11042271 PMID:15282320 NCBI chr 6:132,680,849...132,714,055
Ensembl chr 6:132,680,849...132,714,055 		JBrowse link
N-acetylcysteamine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G EGFR epidermal growth factor receptor decreases phosphorylation EXP 2-acetamidoethanethiol analog results in decreased phosphorylation of EGFR protein CTD PMID:20058253 NCBI chr 7:55,019,017...55,211,628
Ensembl chr 7:55,019,017...55,211,628 		JBrowse link
G ERBB2 erb-b2 receptor tyrosine kinase 2 multiple interactions EXP 2-acetamidoethanethiol analog results in decreased activity of and results in decreased phosphorylation of ERBB2 protein CTD PMID:20058253 NCBI chr17:39,688,094...39,728,658
Ensembl chr17:39,687,914...39,730,426 		JBrowse link
G ERBB3 erb-b2 receptor tyrosine kinase 3 decreases phosphorylation EXP 2-acetamidoethanethiol analog results in decreased phosphorylation of ERBB3 protein CTD PMID:20058253 NCBI chr12:56,080,108...56,103,505
Ensembl chr12:56,076,799...56,103,505 		JBrowse link
sulfluramid term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABCA1 ATP binding cassette subfamily A member 1 increases expression EXP sulfluramid results in increased expression of ABCA1 mRNA CTD PMID:35337807 NCBI chr 9:104,781,006...104,928,155
Ensembl chr 9:104,781,006...104,928,155 		JBrowse link
G ACOT2 acyl-CoA thioesterase 2 increases expression EXP sulfluramid results in increased expression of ACOT2 mRNA CTD PMID:35337807 NCBI chr14:73,567,620...73,575,658
Ensembl chr14:73,567,620...73,575,658 		JBrowse link
G CYP2B6 cytochrome P450 family 2 subfamily B member 6 increases expression EXP sulfluramid results in increased expression of CYP2B6 mRNA CTD PMID:35337807 NCBI chr19:40,991,282...41,018,398
Ensembl chr19:40,991,282...41,018,398 		JBrowse link
G CYP4A11 cytochrome P450 family 4 subfamily A member 11 increases expression EXP sulfluramid results in increased expression of CYP4A11 mRNA CTD PMID:35337807 NCBI chr 1:46,929,188...46,941,476
Ensembl chr 1:46,929,177...46,941,484 		JBrowse link
G CYP7A1 cytochrome P450 family 7 subfamily A member 1 increases expression EXP sulfluramid results in increased expression of CYP7A1 mRNA CTD PMID:35337807 NCBI chr 8:58,490,178...58,500,163
Ensembl chr 8:58,490,178...58,500,163 		JBrowse link
G EHHADH enoyl-CoA hydratase and 3-hydroxyacyl CoA dehydrogenase increases expression EXP sulfluramid results in increased expression of EHHADH mRNA CTD PMID:35337807 NCBI chr 3:185,190,624...185,254,049
Ensembl chr 3:185,190,624...185,281,990 		JBrowse link
G FASN fatty acid synthase increases expression EXP sulfluramid results in increased expression of FASN mRNA CTD PMID:35337807 NCBI chr17:82,078,338...82,098,236
Ensembl chr17:82,078,338...82,098,294 		JBrowse link
G GPAM glycerol-3-phosphate acyltransferase, mitochondrial increases expression EXP sulfluramid results in increased expression of GPAM mRNA CTD PMID:35337807 NCBI chr10:112,149,865...112,227,677
Ensembl chr10:112,149,865...112,215,377 		JBrowse link
G GSTA1 glutathione S-transferase alpha 1 increases expression EXP sulfluramid results in increased expression of GSTA1 mRNA CTD PMID:35337807 NCBI chr 6:52,791,371...52,803,816
Ensembl chr 6:52,791,371...52,803,860 		JBrowse link
G HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 increases expression EXP sulfluramid results in increased expression of HMGCS1 mRNA CTD PMID:35337807 NCBI chr 5:43,287,470...43,313,412
Ensembl chr 5:43,287,470...43,313,512 		JBrowse link
G MTTP microsomal triglyceride transfer protein increases expression EXP sulfluramid results in increased expression of MTTP mRNA CTD PMID:35337807 NCBI chr 4:99,564,130...99,623,997
Ensembl chr 4:99,564,081...99,623,997 		JBrowse link
G NFE2L2 NFE2 like bZIP transcription factor 2 increases expression EXP sulfluramid results in increased expression of NFE2L2 mRNA CTD PMID:35337807 NCBI chr 2:177,230,303...177,264,727
Ensembl chr 2:177,218,667...177,392,756 		JBrowse link
G NQO1 NAD(P)H quinone dehydrogenase 1 increases expression EXP sulfluramid results in increased expression of NQO1 mRNA CTD PMID:35337807 NCBI chr16:69,709,401...69,726,560
Ensembl chr16:69,706,996...69,726,668 		JBrowse link
G NR1I2 nuclear receptor subfamily 1 group I member 2 increases expression EXP sulfluramid results in increased expression of NR1I2 mRNA CTD PMID:35337807 NCBI chr 3:119,782,101...119,818,487
Ensembl chr 3:119,780,484...119,818,487 		JBrowse link
G NR1I3 nuclear receptor subfamily 1 group I member 3 increases expression EXP sulfluramid results in increased expression of NR1I3 mRNA CTD PMID:35337807 NCBI chr 1:161,229,669...161,238,203
Ensembl chr 1:161,229,666...161,238,244 		JBrowse link
G PCK2 phosphoenolpyruvate carboxykinase 2, mitochondrial increases expression EXP sulfluramid results in increased expression of PCK2 mRNA CTD PMID:35337807 NCBI chr14:24,094,171...24,104,125
Ensembl chr14:24,094,053...24,110,598 		JBrowse link
G PPARA peroxisome proliferator activated receptor alpha increases expression
affects binding		 EXP sulfluramid results in increased expression of PPARA mRNA
sulfluramid binds to PPARA protein		 CTD PMID:35337807 PMID:35752307 NCBI chr22:46,150,526...46,243,756
Ensembl chr22:46,150,521...46,243,755 		JBrowse link
G PPARG peroxisome proliferator activated receptor gamma increases expression
affects binding		 EXP
ISO		 sulfluramid results in increased expression of PPARG mRNA
sulfluramid binds to PPARG protein		 CTD PMID:35337807 PMID:35752307 NCBI chr 3:12,287,368...12,434,344
Ensembl chr 3:12,287,368...12,434,356 		JBrowse link
G SAA1 serum amyloid A1 decreases expression EXP sulfluramid results in decreased expression of SAA1 mRNA CTD PMID:35337807 NCBI chr11:18,266,264...18,269,967
Ensembl chr11:18,266,260...18,269,977 		JBrowse link
G SCD stearoyl-CoA desaturase increases expression EXP sulfluramid results in increased expression of SCD mRNA CTD PMID:35337807 NCBI chr10:100,347,233...100,364,826
Ensembl chr10:100,347,233...100,364,826 		JBrowse link
G SLC27A1 solute carrier family 27 member 1 increases expression EXP sulfluramid results in increased expression of SLC27A1 mRNA CTD PMID:35337807 NCBI chr19:17,468,767...17,506,168
Ensembl chr19:17,468,769...17,506,168 		JBrowse link
G SLCO1B1 solute carrier organic anion transporter family member 1B1 increases expression EXP sulfluramid results in increased expression of SLCO1B1 mRNA CTD PMID:35337807 NCBI chr12:21,131,194...21,239,796
Ensembl chr12:21,131,194...21,239,796 		JBrowse link
G SOD1 superoxide dismutase 1 increases expression EXP sulfluramid results in increased expression of SOD1 mRNA CTD PMID:35337807 NCBI chr21:31,659,693...31,668,931
Ensembl chr21:31,659,666...31,668,931 		JBrowse link
G SREBF1 sterol regulatory element binding transcription factor 1 increases expression EXP sulfluramid results in increased expression of SREBF1 mRNA CTD PMID:35337807 NCBI chr17:17,811,334...17,836,986
Ensembl chr17:17,810,399...17,837,002 		JBrowse link
G SULT2A1 sulfotransferase family 2A member 1 increases expression EXP sulfluramid results in increased expression of SULT2A1 mRNA CTD PMID:35337807 NCBI chr19:47,870,467...47,886,315
Ensembl chr19:47,870,467...47,886,315 		JBrowse link
WR-1065 term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CAT catalase increases expression EXP N-(2-mercaptoethyl)-1,3-diaminopropane results in increased expression of CAT protein CTD PMID:17388698 NCBI chr11:34,438,934...34,472,060
Ensembl chr11:34,438,934...34,472,060 		JBrowse link
G CCL5 C-C motif chemokine ligand 5 increases expression EXP N-(2-mercaptoethyl)-1,3-diaminopropane results in increased expression of CCL5 mRNA CTD PMID:12007958 NCBI chr17:35,871,491...35,880,360
Ensembl chr17:35,871,491...35,880,793 		JBrowse link
G GSTP1 glutathione S-transferase pi 1 decreases expression EXP N-(2-mercaptoethyl)-1,3-diaminopropane results in decreased expression of GSTP1 mRNA CTD PMID:12007958 NCBI chr11:67,583,812...67,586,653
Ensembl chr11:67,583,742...67,586,656 		JBrowse link
G IL2RA interleukin 2 receptor subunit alpha increases expression EXP N-(2-mercaptoethyl)-1,3-diaminopropane results in increased expression of IL2RA mRNA CTD PMID:12007958 NCBI chr10:6,010,689...6,062,367
Ensembl chr10:6,010,689...6,062,370 		JBrowse link
G MYB MYB proto-oncogene, transcription factor increases expression EXP N-(2-mercaptoethyl)-1,3-diaminopropane results in increased expression of MYB mRNA CTD PMID:12007958 NCBI chr 6:135,181,308...135,219,172
Ensembl chr 6:135,181,308...135,219,173 		JBrowse link
G MYC MYC proto-oncogene, bHLH transcription factor decreases expression EXP N-(2-mercaptoethyl)-1,3-diaminopropane results in decreased expression of MYC mRNA CTD PMID:12007958 NCBI chr 8:127,735,434...127,742,951
Ensembl chr 8:127,735,434...127,742,951 		JBrowse link
G NFKB1 nuclear factor kappa B subunit 1 multiple interactions EXP N-(2-mercaptoethyl)-1,3-diaminopropane results in increased activity of [NFKB1 protein binds to RELA protein]; N-(2-mercaptoethyl)-1,3-diaminopropane results in increased activity of [RELA protein binds to NFKB1 protein] CTD PMID:11390188 PMID:11917294 PMID:12007958 NCBI chr 4:102,501,359...102,617,302
Ensembl chr 4:102,501,330...102,617,302 		JBrowse link
G RELA RELA proto-oncogene, NF-kB subunit multiple interactions EXP N-(2-mercaptoethyl)-1,3-diaminopropane results in increased activity of [NFKB1 protein binds to RELA protein]; N-(2-mercaptoethyl)-1,3-diaminopropane results in increased activity of [RELA protein binds to NFKB1 protein] CTD PMID:11390188 PMID:11917294 PMID:12007958 NCBI chr11:65,653,601...65,663,857
Ensembl chr11:65,653,599...65,663,090 		JBrowse link
G SOD2 superoxide dismutase 2 multiple interactions
increases activity
increases expression		 EXP
ISO		 helenalin inhibits the reaction [N-(2-mercaptoethyl)-1,3-diaminopropane results in increased expression of SOD2 protein]; N-(2-mercaptoethyl)-1,3-diaminopropane results in increased expression of and results in increased activity of SOD2 protein
N-(2-mercaptoethyl)-1,3-diaminopropane results in increased activity of SOD2
N-(2-mercaptoethyl)-1,3-diaminopropane results in increased expression of SOD2 mRNA; N-(2-mercaptoethyl)-1,3-diaminopropane results in increased expression of SOD2 protein
[TNFRSF1A protein co-treated with TNFRSF1B protein] affects the reaction [N-(2-mercaptoethyl)-1,3-diaminopropane results in increased activity of SOD2]; TNFRSF1A protein affects the reaction [N-(2-mercaptoethyl)-1,3-diaminopropane results in increased activity of SOD2]		 CTD PMID:11390188 PMID:11917294 PMID:12007958 PMID:16540396 PMID:17388698 More... NCBI chr 6:159,669,069...159,762,281
Ensembl chr 6:159,669,069...159,762,529 		JBrowse link
G TNFRSF1A TNF receptor superfamily member 1A multiple interactions ISO [TNFRSF1A protein co-treated with TNFRSF1B protein] affects the reaction [N-(2-mercaptoethyl)-1,3-diaminopropane results in increased activity of SOD2]; TNFRSF1A protein affects the reaction [N-(2-mercaptoethyl)-1,3-diaminopropane results in increased activity of SOD2] CTD PMID:21945096 NCBI chr12:6,328,771...6,342,076
Ensembl chr12:6,328,757...6,342,114 		JBrowse link
G TNFRSF1B TNF receptor superfamily member 1B multiple interactions ISO [TNFRSF1A protein co-treated with TNFRSF1B protein] affects the reaction [N-(2-mercaptoethyl)-1,3-diaminopropane results in increased activity of SOD2] CTD PMID:21945096 NCBI chr 1:12,166,991...12,209,220
Ensembl chr 1:12,166,991...12,209,228 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 26034
    role 25961
      application 25172
        NMR chemical shift reference compound 20287
          ammonia 19941
            organic amino compound 19941
              amine 8471
                primary amine 6517
                  primary aliphatic amine 192
                    ethylamine 69
                      2-aminoethyl group 0
                      cysteamine + 44
                      sulfluramid 25
Path 2
Term Annotations click to browse term
  CHEBI ontology 26034
    subatomic particle 26009
      composite particle 26009
        hadron 26020
          baryon 26009
            nucleon 26009
              atomic nucleus 26009
                atom 26009
                  main group element atom 25834
                    main group molecular entity 25834
                      s-block molecular entity 25166
                        hydrogen molecular entity 24765
                          hydrides 22965
                            inorganic hydride 20483
                              pnictogen hydride 20424
                                nitrogen hydride 20200
                                  azane 19942
                                    ammonia 19941
                                      organic amino compound 19941
                                        primary amino compound 9935
                                          primary amine 6517
                                            primary aliphatic amine 192
                                              ethylamine 69
                                                2-aminoethyl group 0
                                                cysteamine + 44
                                                sulfluramid 25
paths to the root