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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:cephalosporin C
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Accession:CHEBI:15776 term browser browse the term
Definition:A cephalosporin antibiotic carrying a 3-acetoxymethyl substituent and a 6-oxo-N(6)-L-lysino group at position 7.
Synonyms:exact_synonym: (6R,7R)-3-[(acetyloxy)methyl]-7-{[(5R)-5-amino-5-carboxypentanoyl]amino}-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
 related_synonym: 7-(5-Amino-5-carboxyvaleramido)cephalosporanic acid;   Formula=C16H21N3O8S;   InChI=1S/C16H21N3O8S/c1-7(20)27-5-8-6-28-14-11(13(22)19(14)12(8)16(25)26)18-10(21)4-2-3-9(17)15(23)24/h9,11,14H,2-6,17H2,1H3,(H,18,21)(H,23,24)(H,25,26)/t9-,11-,14-/m1/s1;   InChIKey=HOKIDJSKDBPKTQ-GLXFQSAKSA-N;   SMILES=[H][C@]12SCC(COC(C)=O)=C(N1C(=O)[C@H]2NC(=O)CCC[C@@H](N)C(O)=O)C(O)=O
 alt_id: CHEBI:13953;   CHEBI:23065;   CHEBI:3539
 xref: Beilstein:65348;   CAS:61-24-5;   DrugBank:DB03313;   HMDB:HMDB0060450;   KEGG:C00916
 xref_mesh: MESH:C025163
 xref: MetaCyc:CSC;   PDBeChem:CSC;   PMID:13315229;   PMID:14370161;   PMID:18279889;   PMID:19787461;   PMID:20171092;   PMID:20391764;   PMID:2083978;   PMID:21219942;   PMID:21866341;   PMID:22068491;   PMID:23053347;   PMID:23334835;   PMID:23828600;   PMID:9131470;   Reaxys:65348;   Wikipedia:Cephalosporin_C
 cyclic_relationship: is_conjugate_acid_of CHEBI:57511


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cephalosporin C term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcc4 ATP binding cassette subfamily C member 4 increases transport ISO ABCC4 protein results in increased transport of cephalosporin C CTD PMID:17939016 NCBI chr15:103,695,415...103,927,980
Ensembl chr15:103,696,557...103,927,592
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Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19770
    role 19720
      application 19411
        pharmaceutical 19299
          drug 19299
            drug allergen 9925
              cephalosporin 543
                cephalosporin C 1
                  deacetoxycephalosporin C 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19770
    subatomic particle 19768
      composite particle 19768
        hadron 19768
          baryon 19768
            nucleon 19768
              atomic nucleus 19768
                atom 19768
                  main group element atom 19662
                    p-block element atom 19662
                      carbon group element atom 19580
                        carbon atom 19571
                          organic molecular entity 19571
                            organic group 18602
                              organic divalent group 18593
                                organodiyl group 18593
                                  carbonyl group 18506
                                    carbonyl compound 18506
                                      carboxylic acid 18158
                                        carboacyl group 17412
                                          univalent carboacyl group 17412
                                            carbamoyl group 17208
                                              carboxamide 17208
                                                lactam 8048
                                                  beta-lactam 794
                                                    beta-lactam antibiotic 779
                                                      cephem 544
                                                        cephalosporin 543
                                                          cephalosporanic acid 14
                                                            cephalosporin C 1
                                                              deacetoxycephalosporin C 0
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