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ONTOLOGY REPORT - ANNOTATIONS


Term:succinic acid
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Accession:CHEBI:15741 term browser browse the term
Definition:An alpha,omega-dicarboxylic acid resulting from the formal oxidation of each of the terminal methyl groups of butane to the corresponding carboxy group. It is an intermediate metabolite in the citric acid cycle.
Synonyms:related_synonym: 1,2-ethanedicarboxylic acid;   Bernsteinsaeure;   Butandisaeure;   Butanedionic acid;   Dihydrofumaric acid;   E363;   Ethylenesuccinic acid;   Formula=C4H6O4;   HOOC-CH2-CH2-COOH;   InChI=1S/C4H6O4/c5-3(6)1-2-4(7)8/h1-2H2,(H,5,6)(H,7,8);   InChIKey=KDYFGRWQOYBRFD-UHFFFAOYSA-N;   SMILES=OC(=O)CCC(O)=O;   acide butanedioique;   acide succinique;   acidum succinicum;   amber acid;   asuccin;   butanedioic acid;   spirit of amber
 alt_id: CHEBI:22943;   CHEBI:26807;   CHEBI:45639;   CHEBI:9304
 xref: Beilstein:1754069 "Beilstein";   CAS:110-15-6 "ChemIDplus";   CAS:110-15-6 "KEGG COMPOUND";   CAS:110-15-6 "NIST Chemistry WebBook";   DrugBank:DB00139;   Drug_Central:2487 "DrugCentral";   ECMDB:ECMDB00254;   Gmelin:2785 "Gmelin";   HMDB:HMDB0000254;   KEGG:C00042;   KNApSAcK:C00001205;   LIPID_MAPS_instance:LMFA01170043 "LIPID MAPS"
 xref_mesh: MESH:D019802
 xref: MetaCyc:SUC;   PDBeChem:SIN;   PMID:17439666 "Europe PMC";   Reaxys:1754069 "Reaxys";   Wikipedia:Succinic_acid;   YMDB:YMDB00338
 cyclic_relationship: is_conjugate_acid_of CHEBI:30779


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succinic acid term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Bax BCL2 associated X, apoptosis regulator JBrowse link 1 101,451,801 101,457,207 RGD:6480464
G Bcl2l1 Bcl2-like 1 JBrowse link 3 148,259,594 148,314,191 RGD:6480464
G Col2a1 collagen type II alpha 1 chain JBrowse link 7 139,454,945 139,484,403 RGD:6480464
G Dek DEK proto-oncogene JBrowse link 17 17,965,872 17,987,836 RGD:6480464
G Ercc6 ERCC excision repair 6, chromatin remodeling factor JBrowse link 16 8,734,028 8,804,610 RGD:6480464
G Hif1a hypoxia inducible factor 1 subunit alpha JBrowse link 6 96,810,868 96,856,303 RGD:6480464
G Lepr leptin receptor JBrowse link 5 120,503,475 120,682,281 RGD:6480464
G Myc MYC proto-oncogene, bHLH transcription factor JBrowse link 7 102,586,313 102,591,240 RGD:6480464
G Nfkb1 nuclear factor kappa B subunit 1 JBrowse link 2 240,773,520 240,890,053 RGD:6480464
G Nr4a1 nuclear receptor subfamily 4, group A, member 1 JBrowse link 7 142,899,358 142,920,216 RGD:6480464
G Ptgs2 prostaglandin-endoperoxide synthase 2 JBrowse link 13 67,351,230 67,356,920 RGD:6480464
G Rela RELA proto-oncogene, NF-kB subunit JBrowse link 1 220,992,770 221,003,249 RGD:6480464
G Slc13a3 solute carrier family 13 member 3 JBrowse link 3 162,084,336 162,147,398 RGD:6480464
G Slc22a25 solute carrier family 22, member 25 JBrowse link 1 224,596,886 224,698,512 RGD:6480464
G Slco1a4 solute carrier organic anion transporter family, member 1a4 JBrowse link 4 175,969,549 176,026,227 RGD:6480464
G Stat3 signal transducer and activator of transcription 3 JBrowse link 10 88,790,401 88,842,263 RGD:6480464
artesunate term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Aifm1 apoptosis inducing factor, mitochondria associated 1 JBrowse link X 135,304,063 135,343,062 RGD:6480464
G Ar androgen receptor JBrowse link X 67,656,253 67,828,998 RGD:6480464
G Bax BCL2 associated X, apoptosis regulator JBrowse link 1 101,451,801 101,457,207 RGD:6480464
G Bcl2 BCL2, apoptosis regulator JBrowse link 13 26,605,426 26,769,374 RGD:6480464
G Bst1 bone marrow stromal cell antigen 1 JBrowse link 14 71,798,218 71,814,540 RGD:6480464
G Casp3 caspase 3 JBrowse link 16 48,845,011 48,863,249 RGD:6480464
G Casp9 caspase 9 JBrowse link 5 160,356,211 160,373,774 RGD:6480464
G Cat catalase JBrowse link 3 93,379,872 93,412,058 RGD:6480464
G Cct2 chaperonin containing TCP1 subunit 2 JBrowse link 7 60,106,532 60,122,779 RGD:6480464
G Clip4 CAP-GLY domain containing linker protein family, member 4 JBrowse link 6 23,222,020 23,316,962 RGD:6480464
G Coq8a coenzyme Q8A JBrowse link 13 98,451,629 98,480,438 RGD:6480464
G Ctnnb1 catenin beta 1 JBrowse link 8 129,601,511 129,628,378 RGD:6480464
G Dbh dopamine beta-hydroxylase JBrowse link 3 5,709,236 5,731,895 RGD:6480464
G Esr1 estrogen receptor 1 JBrowse link 1 41,192,029 41,594,799 RGD:6480464
G Fas Fas cell surface death receptor JBrowse link 1 252,589,785 252,624,790 RGD:6480464
G Flna filamin A JBrowse link X 156,460,785 156,487,245 RGD:6480464
G Fzd7 frizzled class receptor 7 JBrowse link 9 66,305,731 66,308,550 RGD:6480464
G Gclc glutamate-cysteine ligase, catalytic subunit JBrowse link 8 85,059,051 85,097,471 RGD:6480464
G Gclm glutamate cysteine ligase, modifier subunit JBrowse link 2 225,827,504 225,847,876 RGD:6480464
G Gstm4 glutathione S-transferase mu 4 JBrowse link 2 210,834,013 210,839,242 RGD:6480464
G Gstp1 glutathione S-transferase pi 1 JBrowse link 1 219,291,679 219,294,147 RGD:6480464
G Gstt2 glutathione S-transferase, theta 2 JBrowse link 20 13,760,810 13,764,481 RGD:6480464
G Gstz1 glutathione S-transferase zeta 1 JBrowse link 6 111,176,798 111,187,246 RGD:6480464
G Il1b interleukin 1 beta JBrowse link 3 121,876,256 121,882,637 RGD:6480464
G Il6 interleukin 6 JBrowse link 4 3,043,231 3,047,807 RGD:6480464
G Itgb1 integrin subunit beta 1 JBrowse link 19 61,677,512 61,725,537 RGD:6480464
G Mgst3 microsomal glutathione S-transferase 3 JBrowse link 13 85,601,499 85,622,392 RGD:6480464
G Mki67 marker of proliferation Ki-67 JBrowse link 1 207,993,895 208,020,454 RGD:6480464
G Mmp9 matrix metallopeptidase 9 JBrowse link 3 161,413,410 161,421,473 RGD:6480464
G Mpo myeloperoxidase JBrowse link 10 75,087,892 75,098,260 RGD:6480464
G Mthfd2 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase JBrowse link 4 115,004,433 115,015,965 RGD:6480464
G Myd88 MYD88, innate immune signal transduction adaptor JBrowse link 8 128,022,512 128,027,462 RGD:6480464
G Naca nascent polypeptide associated complex subunit alpha JBrowse link 7 2,458,283 2,470,674 RGD:6480464
G Nckap1 NCK-associated protein 1 JBrowse link 3 67,725,180 67,804,680 RGD:6480464
G Nfe2l2 nuclear factor, erythroid 2-like 2 JBrowse link 3 62,497,568 62,525,146 RGD:6480464
G Nlrp3 NLR family, pyrin domain containing 3 JBrowse link 10 45,884,324 45,918,290 RGD:6480464
G Parp1 poly (ADP-ribose) polymerase 1 JBrowse link 13 98,857,255 98,889,444 RGD:6480464
G Pcna proliferating cell nuclear antigen JBrowse link 3 124,880,698 124,884,570 RGD:6480464
G Pgr progesterone receptor JBrowse link 8 7,128,656 7,187,796 RGD:6480464
G Rela RELA proto-oncogene, NF-kB subunit JBrowse link 1 220,992,770 221,003,249 RGD:6480464
G Rpl41 ribosomal protein L41 JBrowse link 7 2,972,897 2,973,977 RGD:6480464
G Rpl6 ribosomal protein L6 JBrowse link 12 40,877,578 40,882,032 RGD:6480464
G Rpl7 ribosomal protein L7 JBrowse link 5 2,633,517 2,636,525 RGD:6480464
G Rps12 ribosomal protein S12 JBrowse link 1 22,758,214 22,760,370 RGD:6480464
G Rps15a ribosomal protein S15a JBrowse link 1 187,759,865 187,766,734 RGD:6480464
G Rps6 ribosomal protein S6 JBrowse link 5 105,197,821 105,200,681 RGD:6480464
G Slc25a19 solute carrier family 25 member 19 JBrowse link 10 104,166,594 104,179,523 RGD:6480464
G Sp1 Sp1 transcription factor JBrowse link 7 144,014,173 144,044,635 RGD:6480464
G Srsf2 serine and arginine rich splicing factor 2 JBrowse link 10 105,792,779 105,795,986 RGD:6480464
G Tlr4 toll-like receptor 4 JBrowse link 5 82,587,424 82,601,056 RGD:6480464
G Tnf tumor necrosis factor JBrowse link 20 5,189,382 5,192,000 RGD:6480464
G Tpt1 tumor protein, translationally-controlled 1 JBrowse link 15 57,891,680 57,894,504 RGD:6480464
G Tufm Tu translation elongation factor, mitochondrial JBrowse link 1 197,903,582 197,907,189 RGD:6480464
G Vegfa vascular endothelial growth factor A JBrowse link 9 17,340,341 17,355,681 RGD:6480464
G Yy1 YY1 transcription factor JBrowse link 6 132,702,443 132,726,848 RGD:6480464
G Zbtb4 zinc finger and BTB domain containing 4 JBrowse link 10 56,367,586 56,388,296 RGD:6480464
diethyl malate term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Acta2 actin alpha 2, smooth muscle JBrowse link 1 252,537,614 252,550,394 RGD:6480464
G Actc1 actin, alpha, cardiac muscle 1 JBrowse link 3 105,507,403 105,512,939 RGD:6480464
G Actn3 actinin alpha 3 JBrowse link 1 220,120,532 220,136,460 RGD:6480464
G Adcy1 adenylate cyclase 1 JBrowse link 14 87,311,970 87,429,880 RGD:6480464
G Adh1 alcohol dehydrogenase 1 (class I) JBrowse link 2 243,550,655 243,562,243 RGD:6480464
G Agt angiotensinogen JBrowse link 19 57,321,594 57,333,460 RGD:6480464
G C3 complement C3 JBrowse link 9 9,721,137 9,747,084 RGD:6480464
G Cacnb2 calcium voltage-gated channel auxiliary subunit beta 2 JBrowse link 17 81,673,862 82,019,219 RGD:6480464
G Cacnb4 calcium voltage-gated channel auxiliary subunit beta 4 JBrowse link 3 37,950,846 38,211,478 RGD:6480464
G Camk2a calcium/calmodulin-dependent protein kinase II alpha JBrowse link 18 56,193,978 56,295,869 RGD:6480464
G Ccl20 C-C motif chemokine ligand 20 JBrowse link 9 88,918,359 88,921,017 RGD:6480464
G Ccl6 chemokine (C-C motif) ligand 6 JBrowse link 10 70,798,118 70,802,750 RGD:6480464
G Ccl7 C-C motif chemokine ligand 7 JBrowse link 10 69,423,083 69,424,933 RGD:6480464
G Col11a1 collagen type XI alpha 1 chain JBrowse link 2 216,863,423 217,056,523 RGD:6480464
G Col2a1 collagen type II alpha 1 chain JBrowse link 7 139,454,945 139,484,403 RGD:6480464
G Col3a1 collagen type III alpha 1 chain JBrowse link 9 52,023,295 52,059,221 RGD:6480464
G Col6a1 collagen type VI alpha 1 chain JBrowse link 20 12,657,913 12,676,370 RGD:6480464
G Comp cartilage oligomeric matrix protein JBrowse link 16 20,798,437 20,807,070 RGD:6480464
G Cxcl12 C-X-C motif chemokine ligand 12 JBrowse link 4 149,261,044 149,273,891 RGD:6480464
G Cxcl3 C-X-C motif chemokine ligand 3 JBrowse link 14 18,820,168 18,839,659 RGD:6480464
G Cyp2j4 cytochrome P450, family 2, subfamily j, polypeptide 4 JBrowse link 5 119,546,458 119,564,843 RGD:6480464
G Dapk2 death-associated protein kinase 2 JBrowse link 8 71,822,107 71,941,941 RGD:6480464
G Ddx58 DEXD/H-box helicase 58 JBrowse link 5 56,486,584 56,536,898 RGD:6480464
G Dhrs3 dehydrogenase/reductase 3 JBrowse link 5 162,809,090 162,843,385 RGD:6480464
G Dhx58 DEXH-box helicase 58 JBrowse link 10 88,599,722 88,611,562 RGD:6480464
G Edar ectodysplasin-A receptor JBrowse link 20 28,179,132 28,263,092 RGD:6480464
G Ednra endothelin receptor type A JBrowse link 19 33,928,356 33,991,703 RGD:6480464
G Epas1 endothelial PAS domain protein 1 JBrowse link 6 10,306,508 10,385,239 RGD:6480464
G Epha7 Eph receptor A7 JBrowse link 5 43,602,744 43,761,198 RGD:6480464
G Ephb2 Eph receptor B2 JBrowse link 5 155,024,478 155,143,539 RGD:6480464
G Ephb6 Eph receptor B6 JBrowse link 4 70,903,253 70,918,514 RGD:6480464
G Fgf10 fibroblast growth factor 10 JBrowse link 2 51,673,480 51,747,533 RGD:6480464
G Fgf18 fibroblast growth factor 18 JBrowse link 10 18,047,109 18,082,290 RGD:6480464
G Fgfr2 fibroblast growth factor receptor 2 JBrowse link 1 200,590,951 200,696,946 RGD:6480464
G Fst follistatin JBrowse link 2 46,537,589 46,544,813 RGD:6480464
G Fzd2 frizzled class receptor 2 JBrowse link 10 90,550,147 90,552,057 RGD:6480464
G Fzd7 frizzled class receptor 7 JBrowse link 9 66,305,731 66,308,550 RGD:6480464
G Gclc glutamate-cysteine ligase, catalytic subunit JBrowse link 8 85,059,051 85,097,471 RGD:6480464
G Gclm glutamate cysteine ligase, modifier subunit JBrowse link 2 225,827,504 225,847,876 RGD:6480464
G Ggt6 gamma-glutamyl transferase 6 JBrowse link 10 58,995,253 58,998,431 RGD:6480464
G Gli2 GLI family zinc finger 2 JBrowse link 13 34,829,021 35,049,172 RGD:6480464
G Gnao1 G protein subunit alpha o1 JBrowse link 19 11,513,201 11,669,578 RGD:6480464
G Gng7 G protein subunit gamma 7 JBrowse link 7 11,565,740 11,629,519 RGD:6480464
G Gsr glutathione-disulfide reductase JBrowse link 16 62,197,617 62,239,987 RGD:6480464
G Gss glutathione synthetase JBrowse link 3 151,076,254 151,106,557 RGD:6480464
G Gsta2 glutathione S-transferase alpha 2 JBrowse link 8 85,640,081 85,645,621 RGD:6480464
G Gsta3 glutathione S-transferase alpha 3 JBrowse link 9 27,357,490 27,417,023 RGD:6480464
G Gsta6 glutathione S-transferase alpha 6 JBrowse link 9 27,475,273 27,533,939 RGD:6480464
G Gucy1a1 guanylate cyclase 1 soluble subunit alpha 1 JBrowse link 2 181,045,694 181,103,321 RGD:6480464
G Gucy1b1 guanylate cyclase 1 soluble subunit beta 1 JBrowse link 2 180,976,939 181,026,001 RGD:6480464
G Hck HCK proto-oncogene, Src family tyrosine kinase JBrowse link 3 148,579,917 148,623,026 RGD:6480464
G Hgf hepatocyte growth factor JBrowse link 4 15,435,460 15,505,377 RGD:6480464
G Igf1 insulin-like growth factor 1 JBrowse link 7 28,412,123 28,491,815 RGD:6480464
G Il15 interleukin 15 JBrowse link 19 23,542,606 23,624,366 RGD:6480464
G Il18 interleukin 18 JBrowse link 8 55,009,666 55,016,286 RGD:6480464
G Irf7 interferon regulatory factor 7 JBrowse link 1 214,249,388 214,252,909 RGD:6480464
G Isg15 ISG15 ubiquitin-like modifier JBrowse link 5 173,624,862 173,629,124 RGD:6480464
G Itga11 integrin subunit alpha 11 JBrowse link 8 67,566,874 67,683,973 RGD:6480464
G Itga3 integrin subunit alpha 3 JBrowse link 10 82,855,841 82,887,755 RGD:6480464
G Kcnmb4 potassium calcium-activated channel subfamily M regulatory beta subunit 4 JBrowse link 7 59,461,808 59,514,759 RGD:6480464
G Lama1 laminin subunit alpha 1 JBrowse link 9 115,916,907 116,042,123 RGD:6480464
G Lama4 laminin subunit alpha 4 JBrowse link 20 44,060,715 44,201,966 RGD:6480464
G LOC100909797 RT1 class I histocompatibility antigen, AA alpha chain-like JBrowse link 20 3,242,236 3,253,995 RGD:6480464
G Mapk1 mitogen activated protein kinase 1 JBrowse link 11 88,203,863 88,273,301 RGD:6480464
G Mapk3 mitogen activated protein kinase 3 JBrowse link 1 198,192,773 198,198,975 RGD:6480464
G Mrvi1 murine retrovirus integration site 1 homolog JBrowse link 1 175,681,960 175,804,737 RGD:6480464
G Myl9 myosin light chain 9 JBrowse link 3 152,857,573 152,863,961 RGD:6480464
G Odc1 ornithine decarboxylase 1 JBrowse link 6 42,852,529 42,859,142 RGD:6480464
G Pdgfb platelet derived growth factor subunit B JBrowse link 7 121,215,458 121,233,092 RGD:6480464
G Pdgfd platelet derived growth factor D JBrowse link 8 4,441,010 4,666,754 RGD:6480464
G Pf4 platelet factor 4 JBrowse link 14 18,848,549 18,849,258 RGD:6480464
G Pik3ip1 phosphoinositide-3-kinase interacting protein 1 JBrowse link 14 83,559,397 83,572,481 RGD:6480464
G Plxnc1 plexin C1 JBrowse link 7 35,848,083 36,000,969 RGD:6480464
G Prkg1 protein kinase cGMP-dependent 1 JBrowse link 1 248,982,039 250,300,952 RGD:6480464
G Ptgis prostaglandin I2 synthase JBrowse link 3 163,950,746 163,986,129 RGD:6480464
G Ramp2 receptor activity modifying protein 2 JBrowse link 10 89,166,170 89,168,962 RGD:6480464
G Rgs3 regulator of G-protein signaling 3 JBrowse link 5 78,429,017 78,567,281 RGD:6480464
G Runx1t1 RUNX1 partner transcriptional co-repressor 1 JBrowse link 5 27,284,921 27,440,802 RGD:6480464
G Sema3b semaphorin 3B JBrowse link 8 116,353,791 116,362,655 RGD:6480464
G Sema4g semaphorin 4G JBrowse link 1 264,738,935 264,753,399 RGD:6480464
G Sema5a semaphorin 5A JBrowse link 2 85,377,318 85,808,970 RGD:6480464
G Stat1 signal transducer and activator of transcription 1 JBrowse link 9 54,287,540 54,327,958 RGD:6480464
G Tgfb2 transforming growth factor, beta 2 JBrowse link 13 105,039,639 105,142,010 RGD:6480464
G Thbs1 thrombospondin 1 JBrowse link 3 109,862,120 109,873,466 RGD:6480464
G Thbs2 thrombospondin 2 JBrowse link 1 56,653,929 56,683,571 RGD:6480464
G Tnc tenascin C JBrowse link 5 79,789,686 79,874,555 RGD:6480464
G Tnfrsf11b TNF receptor superfamily member 11B JBrowse link 7 93,798,580 93,826,586 RGD:6480464
G Tnnt1 troponin T1, slow skeletal type JBrowse link 1 72,889,270 72,899,629 RGD:6480464
G Tslp thymic stromal lymphopoietin JBrowse link 18 25,613,601 25,618,066 RGD:6480464
hydrocortisone succinate term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 JBrowse link 8 62,451,360 62,458,244 RGD:6480464
G F2 coagulation factor II JBrowse link 3 80,529,468 80,542,993 RGD:6480464
G Il18 interleukin 18 JBrowse link 8 55,009,666 55,016,286 RGD:6480464
G Il1b interleukin 1 beta JBrowse link 3 121,876,256 121,882,637 RGD:6480464
G Il6 interleukin 6 JBrowse link 4 3,043,231 3,047,807 RGD:6480464
G Tnf tumor necrosis factor JBrowse link 20 5,189,382 5,192,000 RGD:6480464
malic acid term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Idh2 isocitrate dehydrogenase (NADP(+)) 2 JBrowse link 1 141,874,354 141,893,674 RGD:6480464
G Mdh1 malate dehydrogenase 1 JBrowse link 14 106,378,349 106,393,642 RGD:6480464
G Nr1h4 nuclear receptor subfamily 1, group H, member 4 JBrowse link 7 30,003,429 30,162,095 RGD:6480464
G Ppargc1a PPARG coactivator 1 alpha JBrowse link 14 63,095,291 63,190,688 RGD:6480464
methylprednisolone succinate term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ces2h carboxylesterase 2H JBrowse link 19 37,052,555 37,067,176 RGD:6480464
monomethyl succinate term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Slc2a4 solute carrier family 2 member 4 JBrowse link 10 56,552,921 56,558,562 RGD:6480464
G Tp53 tumor protein p53 JBrowse link 10 56,186,299 56,198,449 RGD:6480464
oxaloacetic acid term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Got1 glutamic-oxaloacetic transaminase 1 JBrowse link 1 263,246,248 263,269,762 RGD:6480464
G Mdh1 malate dehydrogenase 1 JBrowse link 14 106,378,349 106,393,642 RGD:6480464
G Mt-co2 mitochondrially encoded cytochrome c oxidase II JBrowse link MT 7,006 7,689 RGD:6480464
G Ppargc1a PPARG coactivator 1 alpha JBrowse link 14 63,095,291 63,190,688 RGD:6480464
G Ppargc1b PPARG coactivator 1 beta JBrowse link 18 56,626,725 56,650,524 RGD:6480464
G Pprc1 PPARG related coactivator 1 JBrowse link 1 265,809,892 265,826,319 RGD:6480464
G Sirt1 sirtuin 1 JBrowse link 20 26,831,971 26,851,587 RGD:6480464
G Tfam transcription factor A, mitochondrial JBrowse link 20 18,594,057 18,606,106 RGD:6480464
SAICAR term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Pkm pyruvate kinase M1/2 JBrowse link 8 64,480,963 64,502,957 RGD:6480464
sarpogrelate term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Acat1 acetyl-CoA acetyltransferase 1 JBrowse link 8 58,166,990 58,195,884 RGD:6480464
G Adipoq adiponectin, C1Q and collagen domain containing JBrowse link 11 81,330,845 81,344,488 RGD:6480464
G Adra1a adrenoceptor alpha 1A JBrowse link 15 43,296,997 43,398,314 RGD:6480464
G Adra1b adrenoceptor alpha 1B JBrowse link 10 29,392,762 29,450,644 RGD:6480464
G Adra1d adrenoceptor alpha 1D JBrowse link 3 124,129,558 124,145,566 RGD:6480464
G Akt1 AKT serine/threonine kinase 1 JBrowse link 6 137,218,398 137,239,970 RGD:6480464
G Atp2a2 ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 2 JBrowse link 12 39,553,903 39,603,326 RGD:6480464
G Ccl2 C-C motif chemokine ligand 2 JBrowse link 10 69,412,065 69,413,863 RGD:6480464
G Cyp2d4 cytochrome P450, family 2, subfamily d, polypeptide 4 JBrowse link 7 123,599,264 123,608,436 RGD:6480464
G Fabp1 fatty acid binding protein 1 JBrowse link 4 99,063,181 99,066,957 RGD:6480464
G Htr1b 5-hydroxytryptamine receptor 1B JBrowse link 8 89,113,984 89,130,830 RGD:6480464
G Htr2a 5-hydroxytryptamine receptor 2A JBrowse link 15 56,666,152 56,732,469 RGD:6480464
G Htr2c 5-hydroxytryptamine receptor 2C JBrowse link X 118,084,520 118,318,040 RGD:6480464
G Icam1 intercellular adhesion molecule 1 JBrowse link 8 22,035,287 22,047,049 RGD:6480464
G Il18 interleukin 18 JBrowse link 8 55,009,666 55,016,286 RGD:6480464
G Il6 interleukin 6 JBrowse link 4 3,043,231 3,047,807 RGD:6480464
G Irs1 insulin receptor substrate 1 JBrowse link 9 88,033,668 88,086,488 RGD:6480464
G Kdr kinase insert domain receptor JBrowse link 14 34,727,677 34,787,127 RGD:6480464
G Mmp13 matrix metallopeptidase 13 JBrowse link 8 5,522,739 5,533,018 RGD:6480464
G Mtor mechanistic target of rapamycin kinase JBrowse link 5 165,263,813 165,373,967 RGD:6480464
G Nos3 nitric oxide synthase 3 JBrowse link 4 7,321,908 7,342,404 RGD:6480464
G Pecam1 platelet and endothelial cell adhesion molecule 1 JBrowse link 10 94,850,971 94,913,202 RGD:6480464
G Pln phospholamban JBrowse link 20 34,633,157 34,642,904 RGD:6480464
G Ptgs2 prostaglandin-endoperoxide synthase 2 JBrowse link 13 67,351,230 67,356,920 RGD:6480464
G Serpine2 serpin family E member 2 JBrowse link 9 85,560,852 85,629,410 RGD:6480464
G Slc2a1 solute carrier family 2 member 1 JBrowse link 5 138,154,677 138,182,897 RGD:6480464
G Slc2a4 solute carrier family 2 member 4 JBrowse link 10 56,552,921 56,558,562 RGD:6480464
G Sorl1 sortilin related receptor 1 JBrowse link 8 46,228,077 46,287,171 RGD:6480464
G Tgfb1 transforming growth factor, beta 1 JBrowse link 1 82,480,875 82,497,196 RGD:6480464
G Ugt1a5 UDP glucuronosyltransferase family 1 member A5 JBrowse link 9 95,256,628 95,302,822 RGD:6480464
G Ugt1a9 UDP glucuronosyltransferase family 1 member A9 JBrowse link 9 95,161,157 95,302,822 RGD:6480464
G Vcam1 vascular cell adhesion molecule 1 JBrowse link 2 219,071,193 219,090,931 RGD:6480464
succinylcholine term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Bche butyrylcholinesterase JBrowse link 2 171,104,476 171,196,186 RGD:6480464
G Chrna4 cholinergic receptor nicotinic alpha 4 subunit JBrowse link 3 176,533,182 176,547,965 RGD:6480464
G Chrnb2 cholinergic receptor nicotinic beta 2 subunit JBrowse link 2 189,088,570 189,096,785 RGD:6480464
G Mb myoglobin JBrowse link 7 118,101,633 118,108,864 RGD:6480464
suxibuzone term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Pklr pyruvate kinase L/R JBrowse link 2 188,449,158 188,458,034 RGD:6480464
thiomalic acid term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Endog endonuclease G JBrowse link 3 8,741,833 8,744,414 RGD:6480464
G Gpx1 glutathione peroxidase 1 JBrowse link 8 117,117,430 117,118,528 RGD:6480464

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19728
    role 19675
      application 19328
        pharmaceutical 19202
          drug 19202
            anti-ulcer drug 751
              succinic acid 206
                (2S)-2-isopropyl-3-oxosuccinic acid 0
                (R)-2-(phosphonomethyl)malic acid 0
                (R)-2-ethylmalic acid 0
                (R)-3,3-dimethylmalic acid 0
                (carboxymethoxy)succinic acid 0
                1-hexadecyl-2-succinyl-sn-glycero-3-phosphocholine 0
                11-deoxycorticosterone-21-hemisuccinate 0
                11alpha-hydroxyprogesterone hemisuccinate + 0
                2,2-dimethylsuccinic acid 0
                2-(acetamidomethylidene)succinic acid 0
                2-(phosphinomethylidene)succinic acid 0
                2-benzylsuccinic acid + 0
                2-chlorosuccinic acid 0
                2-hydroxy-3-oxosuccinic acid + 0
                2-isopropylmalic acid + 0
                2-methyl-3-oxosuccinic acid + 0
                2-methylene-3-methylsuccinic acid 0
                2-propylmalic acid + 0
                3-(acetamidomethylidene)-2-(hydroxymethyl)succinic acid 0
                3-carboxypropanoyl group 0
                3-ethylmalic acid 0
                3-hydroxy-2-isopropyl-4-methoxy-4-oxobutanoate 0
                3-hydroxy-2-isopropyl-4-methoxy-4-oxobutanoic acid 0
                3-isopropylmalic acid + 0
                3-methylmalic acid + 0
                3-propylmalic acid 0
                4-(6-hydroxypyridin-3-yl)-4-oxobutyric acid 0
                4-\{[6-endo-amino-6-exo-benzoyl-5-exo-phenylnorbornan-2-yl]oxy\}-4-oxobutanoic acid 0
                4-methoxy-4-oxo-3-phenylbutanoic acid 0
                6beta-hydroxyprogesterone hemisuccinate 0
                N(6)-(1,2-dicarboxyethyl)-AMP 0
                N-succinyl-L-glutamic 5-semialdehyde 0
                SAICAR 1
                bromosuccinic acid 0
                carboxyfentanyl 0
                citramalic acid + 0
                dioxosuccinic acid 0
                ethyl 3-methylbutyl butanedioate 0
                iminoaspartic acid 0
                itaconic acid + 0
                malic acid + 93
                methoxysuccinyl-Ala-Ala-Pro-Ala chloromethyl ketone 0
                methoxysuccinyl-Ala-Ala-Pro-Val chloromethyl ketone 0
                oxaloacetic acid + 8
                phenyl [1-(N-succinylamino)pentyl]phosphonate 0
                succinamic acid + 0
                succinate ester + 96
                succinic anhydride + 0
                succinyl group 0
                succinyladenosine 0
                thiomalic acid + 2
                trans-2,3-epoxysuccinic acid 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19728
    subatomic particle 19724
      composite particle 19724
        hadron 19724
          baryon 19724
            nucleon 19724
              atomic nucleus 19724
                atom 19724
                  main group element atom 19610
                    p-block element atom 19610
                      carbon group element atom 19501
                        carbon atom 19494
                          organic molecular entity 19494
                            organic group 18413
                              organic divalent group 18404
                                organodiyl group 18404
                                  carbonyl group 18293
                                    carbonyl compound 18293
                                      dicarboxylic acids and O-substituted derivatives 10203
                                        dicarboxylic acid 10197
                                          alpha,omega-dicarboxylic acid 2746
                                            succinic acid 206
                                              (2S)-2-isopropyl-3-oxosuccinic acid 0
                                              (R)-2-(phosphonomethyl)malic acid 0
                                              (R)-2-ethylmalic acid 0
                                              (R)-3,3-dimethylmalic acid 0
                                              (carboxymethoxy)succinic acid 0
                                              1-hexadecyl-2-succinyl-sn-glycero-3-phosphocholine 0
                                              11-deoxycorticosterone-21-hemisuccinate 0
                                              11alpha-hydroxyprogesterone hemisuccinate + 0
                                              2,2-dimethylsuccinic acid 0
                                              2-(acetamidomethylidene)succinic acid 0
                                              2-(phosphinomethylidene)succinic acid 0
                                              2-benzylsuccinic acid + 0
                                              2-chlorosuccinic acid 0
                                              2-hydroxy-3-oxosuccinic acid + 0
                                              2-isopropylmalic acid + 0
                                              2-methyl-3-oxosuccinic acid + 0
                                              2-methylene-3-methylsuccinic acid 0
                                              2-propylmalic acid + 0
                                              3-(acetamidomethylidene)-2-(hydroxymethyl)succinic acid 0
                                              3-carboxypropanoyl group 0
                                              3-ethylmalic acid 0
                                              3-hydroxy-2-isopropyl-4-methoxy-4-oxobutanoate 0
                                              3-hydroxy-2-isopropyl-4-methoxy-4-oxobutanoic acid 0
                                              3-isopropylmalic acid + 0
                                              3-methylmalic acid + 0
                                              3-propylmalic acid 0
                                              4-(6-hydroxypyridin-3-yl)-4-oxobutyric acid 0
                                              4-\{[6-endo-amino-6-exo-benzoyl-5-exo-phenylnorbornan-2-yl]oxy\}-4-oxobutanoic acid 0
                                              4-methoxy-4-oxo-3-phenylbutanoic acid 0
                                              6beta-hydroxyprogesterone hemisuccinate 0
                                              N(6)-(1,2-dicarboxyethyl)-AMP 0
                                              N-succinyl-L-glutamic 5-semialdehyde 0
                                              SAICAR 1
                                              bromosuccinic acid 0
                                              carboxyfentanyl 0
                                              citramalic acid + 0
                                              dioxosuccinic acid 0
                                              ethyl 3-methylbutyl butanedioate 0
                                              iminoaspartic acid 0
                                              itaconic acid + 0
                                              malic acid + 93
                                              methoxysuccinyl-Ala-Ala-Pro-Ala chloromethyl ketone 0
                                              methoxysuccinyl-Ala-Ala-Pro-Val chloromethyl ketone 0
                                              oxaloacetic acid + 8
                                              phenyl [1-(N-succinylamino)pentyl]phosphonate 0
                                              succinamic acid + 0
                                              succinate ester + 96
                                              succinic anhydride + 0
                                              succinyl group 0
                                              succinyladenosine 0
                                              thiomalic acid + 2
                                              trans-2,3-epoxysuccinic acid 0
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.