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ONTOLOGY REPORT - ANNOTATIONS


Term:enoxacin
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Accession:CHEBI:157175 term browser browse the term
Definition:A 1,8-naphthyridine derivative that is 1,4-dihydro-1,8-naphthyridine with an ethyl group at the 1 position, a carboxy group at the 3-position, an oxo sustituent at the 4-position, a fluoro substituent at the 5-position and a piperazin-1-yl group at the 7 position. An antibacterial, it is used in the treatment of urinary-tract infections and gonorrhoea.
Synonyms:related_synonym: 1-Ethyl-6-fluoro-4-oxo-7-piperazin-1-yl-1,4-dihydro-[1,8]naphthyridine-3-carboxylic acid;   1-ethyl-6-fluoro-1,4-dihydro-4-oxo-7-(1-piperazinyl)-1,8-naphthyridine-3-carboxylic acid;   Formula=C15H17FN4O3;   InChI=1S/C15H17FN4O3/c1-2-19-8-10(15(22)23)12(21)9-7-11(16)14(18-13(9)19)20-5-3-17-4-6-20/h7-8,17H,2-6H2,1H3,(H,22,23);   InChIKey=IDYZIJYBMGIQMJ-UHFFFAOYSA-N;   SMILES=CCn1cc(C(O)=O)c(=O)c2cc(F)c(nc12)N1CCNCC1;   enoxacine;   enoxacino;   enoxacinum
 alt_id: CHEBI:4796
 xref: Beilstein:3628995 "Beilstein";   CAS:74011-58-8 "ChemIDplus";   CAS:74011-58-8 "KEGG COMPOUND";   DrugBank:DB00467;   Drug_Central:1013 "DrugCentral";   KEGG:C06979;   KEGG:D00310;   LINCS:LSM-5848
 xref_mesh: MESH:D015365
 xref: PMID:16644219 "ChEMBL";   PMID:8741236 "Europe PMC";   Patent:EP9425;   Patent:US4352803;   Patent:US4359578;   Reaxys:3628995 "Reaxys";   VSDB:1896;   Wikipedia:Enoxacin


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enoxacin term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 JBrowse link 8 62,451,360 62,458,244 RGD:6480464
G Gstp1 glutathione S-transferase pi 1 JBrowse link 1 219,291,679 219,294,147 RGD:6480464
G Nos1 nitric oxide synthase 1 JBrowse link 12 44,214,949 44,405,530 RGD:6480464

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19657
    role 19601
      biological role 19599
        antimicrobial agent 17148
          quinolone antibiotic 576
            enoxacin 3
Path 2
Term Annotations click to browse term
  CHEBI ontology 19657
    subatomic particle 19653
      composite particle 19653
        hadron 19653
          baryon 19653
            nucleon 19653
              atomic nucleus 19653
                atom 19653
                  main group element atom 19534
                    p-block element atom 19534
                      carbon group element atom 19417
                        carbon atom 19409
                          organic molecular entity 19409
                            organic molecule 19332
                              organic cyclic compound 19083
                                organic heterocyclic compound 18154
                                  organic heteropolycyclic compound 17419
                                    organic heterobicyclic compound 15891
                                      mancude organic heterobicyclic parent 5098
                                        naphthyridine 759
                                          1,8-naphthyridine 381
                                            1,8-naphthyridine derivative 381
                                              enoxacin 3
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