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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:aldose
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Accession:CHEBI:15693 term browser browse the term
Definition:Aldehydic parent sugars (polyhydroxy aldehydes H[CH(OH)]nC(=O)H, n >= 2) and their intramolecular hemiacetals.
Synonyms:related_synonym: Formula=C2H4O2(CH2O)n;   aldoses;   an aldose
 alt_id: CHEBI:13755;   CHEBI:22305;   CHEBI:2561
 xref: KEGG:C01370;   Wikipedia:Aldose


show annotations for term's descendants           Sort by:
 
2-deoxy-D-glucose term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BAX BCL2 associated X, apoptosis regulator multiple interactions EXP [Antimycin A co-treated with Deoxyglucose] results in increased expression of BAX protein; Quercetin inhibits the reaction [[Antimycin A co-treated with Deoxyglucose] results in increased expression of BAX protein] CTD PMID:25087994 NCBI chr 6:54,222,341...54,228,150
Ensembl chr 6:54,187,260...54,228,144
JBrowse link
G MTOR mechanistic target of rapamycin kinase multiple interactions EXP [Antimycin A co-treated with Deoxyglucose] results in decreased phosphorylation of MTOR protein; Quercetin promotes the reaction [[Antimycin A co-treated with Deoxyglucose] results in decreased phosphorylation of MTOR protein] CTD PMID:25087994 NCBI chr 6:71,286,989...71,412,913
Ensembl chr 6:71,286,989...71,412,888
JBrowse link
G NOS3 nitric oxide synthase 3 decreases expression EXP Deoxyglucose results in decreased expression of NOS3 mRNA CTD PMID:11382920 NCBI chr18:6,209,218...6,228,912
Ensembl chr18:6,209,156...6,228,938
JBrowse link
adenosine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G MYL9 myosin light chain 9 decreases phosphorylation
multiple interactions
EXP Adenosine results in decreased phosphorylation of MYL9 protein
8-phenyltheophylline inhibits the reaction [Adenosine results in decreased phosphorylation of MYL9 protein]
CTD PMID:10942722 NCBI chr17:39,788,165...39,795,240
Ensembl chr17:39,788,199...39,795,296
JBrowse link
aldehydo-D-glucose term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACACA acetyl-CoA carboxylase alpha increases expression
multiple interactions
EXP Glucose results in increased expression of ACACA mRNA
MLXIP protein affects the reaction [Glucose results in increased expression of ACACA mRNA]
CTD PMID:25827716 NCBI chr12:38,580,916...38,875,067
Ensembl chr12:38,581,449...38,875,134
JBrowse link
G ATP6V1G1 ATPase H+ transporting V1 subunit G1 decreases expression EXP Glucose results in decreased expression of ATP6V1G1 mRNA CTD PMID:16313995 NCBI chr 1:255,151,909...255,159,299
Ensembl chr 1:255,151,913...255,195,278
JBrowse link
G FASN fatty acid synthase multiple interactions
increases expression
EXP MLXIP protein affects the reaction [Glucose results in increased expression of FASN mRNA] CTD PMID:25827716 NCBI chr12:922,405...937,560
Ensembl chr12:920,507...937,559
JBrowse link
G INS insulin multiple interactions
increases transport
EXP INS protein promotes the reaction [AZ 002 results in increased uptake of Glucose]; oxophenylarsine inhibits the reaction [INS protein results in increased transport of Glucose]; Sirolimus inhibits the reaction [Glucose results in increased secretion of INS protein] CTD PMID:8048502, PMID:8699633, PMID:20622751 NCBI chr 2:1,496,842...1,498,052
Ensembl chr 2:1,496,842...1,497,841
JBrowse link
G MLXIP MLX interacting protein increases expression
multiple interactions
EXP Glucose results in increased expression of MLXIP mRNA
Glucose promotes the reaction [TO-901317 results in increased expression of MLXIP mRNA]; MLXIP protein affects the reaction [Glucose results in increased expression of ACACA mRNA]; MLXIP protein affects the reaction [Glucose results in increased expression of FASN mRNA]; MLXIP protein affects the reaction [Glucose results in increased expression of SREBF1 mRNA]
CTD PMID:25827716 NCBI chr14:30,575,098...30,646,275
Ensembl chr14:30,577,661...30,646,243
JBrowse link
G NOS2 nitric oxide synthase 2 multiple interactions
increases expression
EXP Kangen-karyu inhibits the reaction [Glucose results in increased expression of NOS2 protein] CTD PMID:16949779 NCBI chr12:44,174,944...44,219,875
Ensembl chr12:44,174,944...44,327,111
JBrowse link
G NR1H3 nuclear receptor subfamily 1 group H member 3 multiple interactions
increases expression
EXP TO-901317 promotes the reaction [Glucose results in increased expression of NR1H3 mRNA] CTD PMID:25827716 NCBI chr 2:15,315,283...15,336,785
Ensembl chr 2:15,270,789...15,334,820
JBrowse link
G PTGS2 prostaglandin-endoperoxide synthase 2 multiple interactions
increases expression
EXP Kangen-karyu inhibits the reaction [Glucose results in increased expression of PTGS2 protein] CTD PMID:16949779 NCBI chr 9:127,850,164...127,858,866
Ensembl chr 9:127,850,013...127,858,884
JBrowse link
G SLC2A1 solute carrier family 2 member 1 increases transport EXP SLC2A1 protein results in increased transport of Glucose CTD PMID:12081571 NCBI chr 6:168,535,398...168,561,170
Ensembl chr 6:168,534,655...168,690,095
JBrowse link
G SREBF1 sterol regulatory element binding transcription factor 1 multiple interactions
increases expression
EXP MLXIP protein affects the reaction [Glucose results in increased expression of SREBF1 mRNA] CTD PMID:25827716 NCBI chr12:60,733,967...60,750,951
Ensembl chr12:60,733,907...60,751,265
JBrowse link
ATP term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BCL2 BCL2 apoptosis regulator multiple interactions
increases expression
EXP tetrakis(N-methyl-4-pyridiniumyl)porphine manganese(III) complex inhibits the reaction [Adenosine Triphosphate results in increased expression of BCL2 protein] CTD PMID:17997382 NCBI chr 1:158,337,403...158,518,214
Ensembl chr 1:158,288,544...158,518,879
JBrowse link
G CASP8 caspase 8 increases activity
multiple interactions
EXP Adenosine Triphosphate results in increased activity of CASP8 protein
tetrakis(N-methyl-4-pyridiniumyl)porphine manganese(III) complex inhibits the reaction [Adenosine Triphosphate results in increased activity of CASP8 protein]
CTD PMID:17997382 NCBI chr15:104,923,659...104,948,470
Ensembl chr15:104,923,953...104,948,470
JBrowse link
G CYCS cytochrome c, somatic affects localization
multiple interactions
EXP Adenosine Triphosphate affects the localization of CYCS protein
[Calcium co-treated with Phosphates co-treated with Adenosine Triphosphate] affects the localization of CYCS protein; tetrakis(N-methyl-4-pyridiniumyl)porphine manganese(III) complex inhibits the reaction [Adenosine Triphosphate affects the localization of CYCS protein]
CTD PMID:16489745, PMID:17997382 NCBI chr18:47,169,921...47,172,212
Ensembl chr18:47,169,866...47,173,866
JBrowse link
G MYL9 myosin light chain 9 decreases phosphorylation
multiple interactions
EXP Adenosine Triphosphate results in decreased phosphorylation of MYL9 protein
1,2-bis(2-aminophenoxy)ethane-N,N,N',N'-tetraacetic acid inhibits the reaction [Adenosine Triphosphate promotes the reaction [calyculin A results in increased phosphorylation of MYL9 protein]]; Adenosine Triphosphate promotes the reaction [calyculin A results in increased phosphorylation of MYL9 protein]
CTD PMID:10942722 NCBI chr17:39,788,165...39,795,240
Ensembl chr17:39,788,199...39,795,296
JBrowse link
G TNF tumor necrosis factor increases expression
multiple interactions
EXP Adenosine Triphosphate results in increased expression of TNF protein
tetrakis(N-methyl-4-pyridiniumyl)porphine manganese(III) complex inhibits the reaction [Adenosine Triphosphate results in increased expression of TNF protein]
CTD PMID:17997382 NCBI chr 7:23,699,635...23,702,393
Ensembl chr 7:23,699,636...23,703,655
JBrowse link
D-glucose term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACACA acetyl-CoA carboxylase alpha increases expression
multiple interactions
EXP Glucose results in increased expression of ACACA mRNA
MLXIP protein affects the reaction [Glucose results in increased expression of ACACA mRNA]
CTD PMID:25827716 NCBI chr12:38,580,916...38,875,067
Ensembl chr12:38,581,449...38,875,134
JBrowse link
G ATP6V1G1 ATPase H+ transporting V1 subunit G1 decreases expression EXP Glucose results in decreased expression of ATP6V1G1 mRNA CTD PMID:16313995 NCBI chr 1:255,151,909...255,159,299
Ensembl chr 1:255,151,913...255,195,278
JBrowse link
G FASN fatty acid synthase multiple interactions
increases expression
EXP MLXIP protein affects the reaction [Glucose results in increased expression of FASN mRNA] CTD PMID:25827716 NCBI chr12:922,405...937,560
Ensembl chr12:920,507...937,559
JBrowse link
G INS insulin multiple interactions
increases transport
EXP INS protein promotes the reaction [AZ 002 results in increased uptake of Glucose]; oxophenylarsine inhibits the reaction [INS protein results in increased transport of Glucose]; Sirolimus inhibits the reaction [Glucose results in increased secretion of INS protein] CTD PMID:8048502, PMID:8699633, PMID:20622751 NCBI chr 2:1,496,842...1,498,052
Ensembl chr 2:1,496,842...1,497,841
JBrowse link
G MLXIP MLX interacting protein increases expression
multiple interactions
EXP Glucose results in increased expression of MLXIP mRNA
Glucose promotes the reaction [TO-901317 results in increased expression of MLXIP mRNA]; MLXIP protein affects the reaction [Glucose results in increased expression of ACACA mRNA]; MLXIP protein affects the reaction [Glucose results in increased expression of FASN mRNA]; MLXIP protein affects the reaction [Glucose results in increased expression of SREBF1 mRNA]
CTD PMID:25827716 NCBI chr14:30,575,098...30,646,275
Ensembl chr14:30,577,661...30,646,243
JBrowse link
G NOS2 nitric oxide synthase 2 increases expression
multiple interactions
EXP Glucose results in increased expression of NOS2 protein
Kangen-karyu inhibits the reaction [Glucose results in increased expression of NOS2 protein]
CTD PMID:16949779 NCBI chr12:44,174,944...44,219,875
Ensembl chr12:44,174,944...44,327,111
JBrowse link
G NR1H3 nuclear receptor subfamily 1 group H member 3 multiple interactions
increases expression
EXP TO-901317 promotes the reaction [Glucose results in increased expression of NR1H3 mRNA] CTD PMID:25827716 NCBI chr 2:15,315,283...15,336,785
Ensembl chr 2:15,270,789...15,334,820
JBrowse link
G PTGS2 prostaglandin-endoperoxide synthase 2 increases expression
multiple interactions
EXP Glucose results in increased expression of PTGS2 protein
Kangen-karyu inhibits the reaction [Glucose results in increased expression of PTGS2 protein]
CTD PMID:16949779 NCBI chr 9:127,850,164...127,858,866
Ensembl chr 9:127,850,013...127,858,884
JBrowse link
G SLC2A1 solute carrier family 2 member 1 increases transport EXP SLC2A1 protein results in increased transport of Glucose CTD PMID:12081571 NCBI chr 6:168,535,398...168,561,170
Ensembl chr 6:168,534,655...168,690,095
JBrowse link
G SREBF1 sterol regulatory element binding transcription factor 1 multiple interactions
increases expression
EXP MLXIP protein affects the reaction [Glucose results in increased expression of SREBF1 mRNA] CTD PMID:25827716 NCBI chr12:60,733,967...60,750,951
Ensembl chr12:60,733,907...60,751,265
JBrowse link
glucose term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACACA acetyl-CoA carboxylase alpha increases expression
multiple interactions
EXP Glucose results in increased expression of ACACA mRNA
MLXIP protein affects the reaction [Glucose results in increased expression of ACACA mRNA]
CTD PMID:25827716 NCBI chr12:38,580,916...38,875,067
Ensembl chr12:38,581,449...38,875,134
JBrowse link
G ATP6V1G1 ATPase H+ transporting V1 subunit G1 decreases expression EXP Glucose results in decreased expression of ATP6V1G1 mRNA CTD PMID:16313995 NCBI chr 1:255,151,909...255,159,299
Ensembl chr 1:255,151,913...255,195,278
JBrowse link
G FASN fatty acid synthase increases expression
multiple interactions
EXP Glucose results in increased expression of FASN mRNA
MLXIP protein affects the reaction [Glucose results in increased expression of FASN mRNA]
CTD PMID:25827716 NCBI chr12:922,405...937,560
Ensembl chr12:920,507...937,559
JBrowse link
G INS insulin multiple interactions
increases transport
EXP INS protein promotes the reaction [AZ 002 results in increased uptake of Glucose]; oxophenylarsine inhibits the reaction [INS protein results in increased transport of Glucose]; Sirolimus inhibits the reaction [Glucose results in increased secretion of INS protein] CTD PMID:8048502, PMID:8699633, PMID:20622751 NCBI chr 2:1,496,842...1,498,052
Ensembl chr 2:1,496,842...1,497,841
JBrowse link
G MLXIP MLX interacting protein multiple interactions
increases expression
EXP Glucose promotes the reaction [TO-901317 results in increased expression of MLXIP mRNA]; MLXIP protein affects the reaction [Glucose results in increased expression of ACACA mRNA]; MLXIP protein affects the reaction [Glucose results in increased expression of FASN mRNA]; MLXIP protein affects the reaction [Glucose results in increased expression of SREBF1 mRNA]
Glucose results in increased expression of MLXIP mRNA
CTD PMID:25827716 NCBI chr14:30,575,098...30,646,275
Ensembl chr14:30,577,661...30,646,243
JBrowse link
G NOS2 nitric oxide synthase 2 multiple interactions
increases expression
EXP Kangen-karyu inhibits the reaction [Glucose results in increased expression of NOS2 protein] CTD PMID:16949779 NCBI chr12:44,174,944...44,219,875
Ensembl chr12:44,174,944...44,327,111
JBrowse link
G NR1H3 nuclear receptor subfamily 1 group H member 3 increases expression
multiple interactions
EXP Glucose results in increased expression of NR1H3 mRNA
TO-901317 promotes the reaction [Glucose results in increased expression of NR1H3 mRNA]
CTD PMID:25827716 NCBI chr 2:15,315,283...15,336,785
Ensembl chr 2:15,270,789...15,334,820
JBrowse link
G PTGS2 prostaglandin-endoperoxide synthase 2 multiple interactions
increases expression
EXP Kangen-karyu inhibits the reaction [Glucose results in increased expression of PTGS2 protein] CTD PMID:16949779 NCBI chr 9:127,850,164...127,858,866
Ensembl chr 9:127,850,013...127,858,884
JBrowse link
G SLC2A1 solute carrier family 2 member 1 increases transport EXP SLC2A1 protein results in increased transport of Glucose CTD PMID:12081571 NCBI chr 6:168,535,398...168,561,170
Ensembl chr 6:168,534,655...168,690,095
JBrowse link
G SREBF1 sterol regulatory element binding transcription factor 1 increases expression
multiple interactions
EXP Glucose results in increased expression of SREBF1 mRNA
MLXIP protein affects the reaction [Glucose results in increased expression of SREBF1 mRNA]
CTD PMID:25827716 NCBI chr12:60,733,967...60,750,951
Ensembl chr12:60,733,907...60,751,265
JBrowse link
neomycin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G SLC5A1 solute carrier family 5 member 1 decreases expression EXP Neomycin results in decreased expression of SLC5A1 mRNA; Neomycin results in decreased expression of SLC5A1 protein CTD PMID:12927799 NCBI chr14:48,566,400...48,704,145
Ensembl chr14:48,566,343...48,705,841
JBrowse link
notoginsenoside R1 term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G IL10 interleukin 10 decreases expression EXP notoginsenoside R1 results in decreased expression of IL10 protein CTD PMID:25721049 NCBI chr 9:67,400,727...67,405,941
Ensembl chr 9:67,400,727...67,405,711
JBrowse link
G IL4 interleukin 4 decreases expression EXP notoginsenoside R1 results in decreased expression of IL4 protein CTD PMID:25721049 NCBI chr 2:134,986,817...134,994,365
Ensembl chr 2:134,986,817...134,994,365
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 860
    chemical entity 860
      atom 845
        nonmetal atom 823
          oxygen atom 744
            oxygen molecular entity 744
              organooxygen compound 450
                carbohydrates and carbohydrate derivatives 107
                  carbohydrate 107
                    monosaccharide 44
                      aldose 21
                        (2S,3R)-aldopyranose 0
                        D-aldose + 0
                        aldoheptose + 0
                        aldohexose + 16
                        aldooctose + 0
                        aldopentose + 5
                        aldose derivative + 0
                        aldotetrose + 0
                        aldotriose + 0
                        an aldopyranose + 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 860
    subatomic particle 845
      composite particle 845
        hadron 845
          baryon 845
            nucleon 845
              atomic nucleus 845
                atom 845
                  main group element atom 834
                    p-block element atom 831
                      carbon group element atom 805
                        carbon atom 804
                          organic molecular entity 804
                            heteroorganic entity 562
                              organochalcogen compound 515
                                organooxygen compound 450
                                  carbohydrates and carbohydrate derivatives 107
                                    carbohydrate 107
                                      monosaccharide 44
                                        aldose 21
                                          (2S,3R)-aldopyranose 0
                                          D-aldose + 0
                                          aldoheptose + 0
                                          aldohexose + 16
                                          aldooctose + 0
                                          aldopentose + 5
                                          aldose derivative + 0
                                          aldotetrose + 0
                                          aldotriose + 0
                                          an aldopyranose + 0
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.