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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:(N(omega)-L-arginino)succinic acid
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Accession:CHEBI:15682 term browser browse the term
Definition:A L-arginine derivative that has formula C10H18N4O6.
Synonyms:exact_synonym: 2-(N(omega)-L-arginino)butanedioic acid
 related_synonym: 2-(Nomega-L-Arginino)succinate;   Formula=C10H18N4O6;   InChI=1S/C10H18N4O6/c11-5(8(17)18)2-1-3-13-10(12)14-6(9(19)20)4-7(15)16/h5-6H,1-4,11H2,(H,15,16)(H,17,18)(H,19,20)(H3,12,13,14)/t5-,6?/m0/s1;   InChIKey=KDZOASGQNOPSCU-ZBHICJROSA-N;   L-Argininosuccinate;   L-Argininosuccinic acid;   L-Arginosuccinic acid;   N(omega)-(L-Arginino)succinate;   N-(L-Arginino)succinate;   SMILES=N[C@@H](CCCNC(=N)NC(CC(O)=O)C(O)=O)C(O)=O
 alt_id: CHEBI:10960;   CHEBI:21475;   CHEBI:7098
 xref: CAS:2387-71-5;   KEGG:C03406;   KNApSAcK:C00019688
 xref_mesh: MESH:D001125
 cyclic_relationship: is_conjugate_acid_of CHEBI:57472


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(N(omega)-L-arginino)succinic acid term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Idh2 isocitrate dehydrogenase 2 (NADP+), mitochondrial decreases abundance
multiple interactions		 EXP IDH2 protein mutant form results in decreased abundance of Argininosuccinic Acid
Triazines inhibits the reaction [IDH2 protein mutant form results in decreased abundance of Argininosuccinic Acid]		 CTD PMID:27469509 NCBI chr 7:79,744,594...79,768,356
Ensembl chr 7:79,744,594...79,765,140 		JBrowse link
G Lepr leptin receptor affects abundance EXP LEPR affects the abundance of Argininosuccinic Acid CTD PMID:20567778 NCBI chr 4:101,574,393...101,676,375
Ensembl chr 4:101,574,601...101,672,549 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 22178
    role 22194
      application 21744
        indicator 8829
          biomarker 6642
            L-arginine 93
              L-arginine derivative 78
                (N(omega)-L-arginino)succinic acid 2
Path 2
Term Annotations click to browse term
  CHEBI ontology 22178
    subatomic particle 22170
      composite particle 22170
        hadron 22201
          baryon 22170
            nucleon 22170
              atomic nucleus 22170
                atom 22170
                  main group element atom 22104
                    main group molecular entity 22104
                      s-block molecular entity 21729
                        hydrogen molecular entity 21646
                          hydrides 20758
                            inorganic hydride 18672
                              pnictogen hydride 18652
                                nitrogen hydride 18519
                                  azane 18426
                                    ammonia 18425
                                      organic amino compound 18425
                                        amino acid 16428
                                          alpha-amino acid 14205
                                            L-alpha-amino acid 13317
                                              glutamine family amino acid 10770
                                                L-arginine 93
                                                  L-arginine derivative 78
                                                    (N(omega)-L-arginino)succinic acid 2
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