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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:(N(omega)-L-arginino)succinic acid
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Accession:CHEBI:15682 term browser browse the term
Definition:A L-arginine derivative that has formula C10H18N4O6.
Synonyms:exact_synonym: 2-(N(omega)-L-arginino)butanedioic acid
 related_synonym: 2-(Nomega-L-Arginino)succinate;   Formula=C10H18N4O6;   InChI=1S/C10H18N4O6/c11-5(8(17)18)2-1-3-13-10(12)14-6(9(19)20)4-7(15)16/h5-6H,1-4,11H2,(H,15,16)(H,17,18)(H,19,20)(H3,12,13,14)/t5-,6?/m0/s1;   InChIKey=KDZOASGQNOPSCU-ZBHICJROSA-N;   L-Argininosuccinate;   L-Argininosuccinic acid;   L-Arginosuccinic acid;   N(omega)-(L-Arginino)succinate;   N-(L-Arginino)succinate;   SMILES=N[C@@H](CCCNC(=N)NC(CC(O)=O)C(O)=O)C(O)=O
 alt_id: CHEBI:10960;   CHEBI:21475;   CHEBI:7098
 xref: CAS:2387-71-5;   KEGG:C03406;   KNApSAcK:C00019688
 xref_mesh: MESH:D001125
 cyclic_relationship: is_conjugate_acid_of CHEBI:57472



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(N(omega)-L-arginino)succinic acid term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Idh2 isocitrate dehydrogenase (NADP(+)) 2 multiple interactions
decreases abundance
ISO Triazines inhibits the reaction [IDH2 protein mutant form results in decreased abundance of Argininosuccinic Acid] CTD PMID:27469509 NCBI chr 1:134,038,644...134,057,969
Ensembl chr 1:134,029,772...134,058,025
JBrowse link
G Lepr leptin receptor affects abundance ISO LEPR affects the abundance of Argininosuccinic Acid CTD PMID:20567778 NCBI chr 5:116,294,409...116,477,904
Ensembl chr 5:116,289,823...116,475,908
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 20056
    role 20008
      application 19745
        indicator 8706
          biomarker 6490
            L-arginine 65
              L-arginine derivative 50
                (N(omega)-L-arginino)succinic acid 2
Path 2
Term Annotations click to browse term
  CHEBI ontology 20056
    subatomic particle 20054
      composite particle 20054
        hadron 20054
          baryon 20054
            nucleon 20054
              atomic nucleus 20054
                atom 20054
                  main group element atom 19956
                    p-block element atom 19956
                      carbon group element atom 19882
                        carbon atom 19875
                          organic molecular entity 19875
                            organic group 18961
                              organic divalent group 18947
                                organodiyl group 18947
                                  carbonyl group 18900
                                    carbonyl compound 18900
                                      carboxylic acid 18594
                                        amino acid 14919
                                          alpha-amino acid 12937
                                            L-alpha-amino acid 11598
                                              glutamine family amino acid 10278
                                                L-arginine 65
                                                  L-arginine derivative 50
                                                    (N(omega)-L-arginino)succinic acid 2
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