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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:(N(omega)-L-arginino)succinic acid
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Accession:CHEBI:15682 term browser browse the term
Definition:A L-arginine derivative that has formula C10H18N4O6.
Synonyms:exact_synonym: 2-(N(omega)-L-arginino)butanedioic acid
 related_synonym: 2-(Nomega-L-Arginino)succinate;   Formula=C10H18N4O6;   InChI=1S/C10H18N4O6/c11-5(8(17)18)2-1-3-13-10(12)14-6(9(19)20)4-7(15)16/h5-6H,1-4,11H2,(H,15,16)(H,17,18)(H,19,20)(H3,12,13,14)/t5-,6?/m0/s1;   InChIKey=KDZOASGQNOPSCU-ZBHICJROSA-N;   L-Argininosuccinate;   L-Argininosuccinic acid;   L-Arginosuccinic acid;   N(omega)-(L-Arginino)succinate;   N-(L-Arginino)succinate;   SMILES=N[C@@H](CCCNC(=N)NC(CC(O)=O)C(O)=O)C(O)=O
 alt_id: CHEBI:10960;   CHEBI:21475;   CHEBI:7098
 xref: CAS:2387-71-5;   KEGG:C03406;   KNApSAcK:C00019688
 xref_mesh: MESH:D001125
 cyclic_relationship: is_conjugate_acid_of CHEBI:57472


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(N(omega)-L-arginino)succinic acid term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Idh2 isocitrate dehydrogenase (NADP(+)) 2 multiple interactions
decreases abundance
ISO Triazines inhibits the reaction [IDH2 protein mutant form results in decreased abundance of Argininosuccinic Acid] CTD PMID:27469509 NCBI chr 1:134,038,644...134,057,969
Ensembl chr 1:134,029,772...134,058,025
JBrowse link
G Lepr leptin receptor affects abundance ISO LEPR affects the abundance of Argininosuccinic Acid CTD PMID:20567778 NCBI chr 5:116,294,409...116,477,904
Ensembl chr 5:116,289,823...116,475,908
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19821
    role 19769
      application 19481
        indicator 8687
          biomarker 6469
            L-arginine 53
              L-arginine derivative 45
                (N(omega)-L-arginino)succinic acid 2
Path 2
Term Annotations click to browse term
  CHEBI ontology 19821
    subatomic particle 19819
      composite particle 19819
        hadron 19819
          baryon 19819
            nucleon 19819
              atomic nucleus 19819
                atom 19819
                  main group element atom 19716
                    p-block element atom 19716
                      carbon group element atom 19640
                        carbon atom 19630
                          organic molecular entity 19630
                            organic group 18737
                              organic divalent group 18728
                                organodiyl group 18728
                                  carbonyl group 18675
                                    carbonyl compound 18675
                                      carboxylic acid 18373
                                        amino acid 14879
                                          alpha-amino acid 12854
                                            L-alpha-amino acid 11559
                                              glutamine family amino acid 10263
                                                L-arginine 53
                                                  L-arginine derivative 45
                                                    (N(omega)-L-arginino)succinic acid 2
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