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The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at The data is made available under the Creative Commons License (CC BY 3.0, For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

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Accession:CHEBI:15676 term browser browse the term
Definition:An imidazolidine-2,4-dione that is 5-aminohydantoin in which a carbamoyl group is attached to the exocyclic nitrogen.
Synonyms:exact_synonym: N-(2,5-dioxoimidazolidin-4-yl)urea
 related_synonym: 2,5-Dioxo-4-imidazolidinyl-urea;   4-ureido-2,5-imidazolidinedione;   5-Ureido-2,4-imidazolidindione;   5-ureidohydantoin;   Formula=C4H6N4O3;   Glyoxyldiureide;   InChI=1S/C4H6N4O3/c5-3(10)6-1-2(9)8-4(11)7-1/h1H,(H3,5,6,10)(H2,7,8,9,11);   InChIKey=POJWUDADGALRAB-UHFFFAOYSA-N;   N-(2,5-Dioxo-4-imidazolidinyl)urea;   SMILES=NC(=O)NC1NC(=O)NC1=O
 alt_id: CHEBI:13761;   CHEBI:22354;   CHEBI:2594
 xref: CAS:97-59-6;   Drug_Central:4268;   HMDB:HMDB0000462;   KEGG:C01551;   KEGG:D00121;   KNApSAcK:C00007468;   LINCS:LSM-5190
 xref_mesh: MESH:D000481
 xref: MetaCyc:ALLANTOIN;   PMID:11157020;   PMID:14619112;   PMID:17190852;   Patent:US2158098;   Reaxys:83514;   Wikipedia:Allantoin
 cyclic_relationship: is_tautomer_of CHEBI:74345

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allantoin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Col2a1 collagen type II alpha 1 chain multiple interactions EXP [COL2A1 protein co-treated with Freund's Adjuvant] results in increased abundance of Allantoin; [geniposide co-treated with phellodendrine co-treated with magnoflorine co-treated with Chlorogenic Acid co-treated with crocin co-treated with Flavonoids co-treated with Berberine Alkaloids] inhibits the reaction [[COL2A1 protein co-treated with Freund's Adjuvant] results in increased abundance of Allantoin]; huang-lien-chieh-tu-tang inhibits the reaction [[COL2A1 protein co-treated with Freund's Adjuvant] results in increased abundance of Allantoin] CTD PMID:24709313 NCBI chr 7:139,454,945...139,484,403
Ensembl chr 7:139,455,242...139,483,997
JBrowse link
G Lepr leptin receptor affects abundance ISO LEPR affects the abundance of Allantoin CTD PMID:20567778 NCBI chr 5:120,503,475...120,682,281
Ensembl chr 5:120,564,645...120,682,221
JBrowse link
G Xdh xanthine dehydrogenase multiple interactions EXP [2,2,5,7,8-pentamethyl-1-hydroxychroman results in decreased activity of XDH protein] which results in decreased abundance of Allantoin CTD PMID:21920950 NCBI chr 6:25,149,570...25,211,273
Ensembl chr 6:25,149,235...25,211,494
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19770
    role 19720
      application 19411
        pharmaceutical 19299
          drug 19299
            vulnerary 916
              allantoin 3
                (R)-(-)-allantoin 0
                (S)-(+)-allantoin + 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19770
    subatomic particle 19768
      composite particle 19768
        hadron 19768
          baryon 19768
            nucleon 19768
              atomic nucleus 19768
                atom 19768
                  main group element atom 19662
                    p-block element atom 19662
                      carbon group element atom 19580
                        carbon atom 19571
                          organic molecular entity 19571
                            organic group 18602
                              organic divalent group 18593
                                organodiyl group 18593
                                  carbonyl group 18506
                                    carbonyl compound 18506
                                      carboxylic acid 18158
                                        carboacyl group 17412
                                          univalent carboacyl group 17412
                                            carbamoyl group 17208
                                              carboxamide 17208
                                                monocarboxylic acid amide 14598
                                                  urea 5021
                                                    ureas 5019
                                                      allantoin 3
                                                        (R)-(-)-allantoin 0
                                                        (S)-(+)-allantoin + 0
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