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ONTOLOGY REPORT - ANNOTATIONS


Term:leukotriene E4
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Accession:CHEBI:15650 term browser browse the term
Definition:A leukotriene that is (7E,9E,11Z,14Z)-icosa-7,9,11,14-tetraenoic acid substituted by a hydroxy group at position 5 (5S) and an L-cystein-S-yl group at position 6 (6R).
Synonyms:exact_synonym: (5S,6R,7E,9E,11Z,14Z)-6-(L-cystein-S-yl)-5-hydroxyicosa-7,9,11,14-tetraenoic acid;   S-{(1R,2E,4E,6Z,9Z)-1-[(1S)-4-carboxy-1-hydroxybutyl]pentadeca-2,4,6,9-tetraen-1-yl}-L-cysteine
 related_synonym: (5S-(5R*,6S*(S*),7E,9E,11Z,14Z))-6-((2-Amino-2-carboxyethyl)thio)-5-hydroxy-7,9,11,14-eicosatetraenoic acid;   (7E,9E,11Z,14Z)-(5S,6R)-6-(Cystein-S-yl)-5-hydroxyeicosa-7,9,11,14-tetraenoate;   (7E,9E,11Z,14Z)-(5S,6R)-6-(Cystein-S-yl)-5-hydroxyicosa-7,9,11,14-tetraenoate;   5S-hydroxy,6R-(S-cysteinyl),7E,9E,11Z,14Z-eicosatetraenoic acid;   Formula=C23H37NO5S;   InChI=1S/C23H37NO5S/c1-2-3-4-5-6-7-8-9-10-11-12-13-16-21(30-18-19(24)23(28)29)20(25)15-14-17-22(26)27/h6-7,9-13,16,19-21,25H,2-5,8,14-15,17-18,24H2,1H3,(H,26,27)(H,28,29)/b7-6-,10-9-,12-11+,16-13+/t19-,20-,21+/m0/s1;   InChIKey=OTZRAYGBFWZKMX-FRFVZSDQSA-N;   LTE4;   SMILES=CCCCC\\C=C/C\\C=C/C=C/C=C/[C@@H](SC[C@H](N)C(O)=O)[C@@H](O)CCCC(O)=O
 alt_id: CHEBI:10936;   CHEBI:18612;   CHEBI:25027;   CHEBI:261;   CHEBI:6424
 xref: CAS:75715-89-8 "ChemIDplus";   CAS:75715-89-8 "KEGG COMPOUND";   KEGG:C05952;   LIPID_MAPS_instance:LMFA03020002 "LIPID MAPS"
 xref_mesh: MESH:D017999
 xref: PMID:19291727 "Europe PMC"
 cyclic_relationship: is_conjugate_acid_of CHEBI:57462


show annotations for term's descendants       view all columns           Sort by:
 
leukotriene E4 term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Alox5 arachidonate 5-lipoxygenase JBrowse link 4 148,398,004 148,446,308 RGD:6480464
G Cysltr1 cysteinyl leukotriene receptor 1 JBrowse link X 77,671,028 77,700,491 RGD:6480464
G Cysltr2 cysteinyl leukotriene receptor 2 JBrowse link 15 54,903,290 54,941,742 RGD:6480464
G Gpr17 G protein-coupled receptor 17 JBrowse link 18 24,733,306 24,739,194 RGD:6480464
G Il13 interleukin 13 JBrowse link 10 38,982,909 38,985,466 RGD:6480464
G Mgst1 microsomal glutathione S-transferase 1 JBrowse link 4 172,119,382 172,134,609 RGD:6480464
G Muc5ac mucin 5AC, oligomeric mucus/gel-forming JBrowse link 1 214,725,482 214,756,653 RGD:6480464
G Ptgs1 prostaglandin-endoperoxide synthase 1 JBrowse link 3 15,560,685 15,582,339 RGD:6480464

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19669
    role 19613
      application 19235
        refrigerant 16994
          ammonia 16561
            organic amino compound 16560
              amino acid 12315
                amino dicarboxylic acid 9
                  leukotriene E4 8
                    16-carboxy-17,18,19,20-tetranor-leukotriene E3 0
                    16-carboxy-Delta(13)-17,18,19,20-tetranor-leukotriene E4 + 0
                    18-carboxy-19,20-dinor-leukotriene E4 0
                    20-carboxyleukotriene E4 0
                    20-hydroxy-leukotriene E4 0
                    20-oxoleukotriene E4 0
                    N-acetylleukotriene E4 0
                    leukotriene E4 methyl ester 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19669
    subatomic particle 19665
      composite particle 19665
        hadron 19665
          baryon 19665
            nucleon 19665
              atomic nucleus 19665
                atom 19665
                  main group element atom 19545
                    p-block element atom 19545
                      carbon group element atom 19428
                        carbon atom 19420
                          organic molecular entity 19420
                            organic group 18343
                              organic divalent group 18334
                                organodiyl group 18334
                                  carbonyl group 18222
                                    carbonyl compound 18222
                                      carboxylic acid 17923
                                        amino acid 12315
                                          alpha-amino acid 7422
                                            L-alpha-amino acid 7079
                                              serine family amino acid 1402
                                                L-cysteine 1097
                                                  L-cysteine derivative 1084
                                                    S-substituted L-cysteine 136
                                                      L-cysteine thioether 56
                                                        leukotriene E4 8
                                                          16-carboxy-17,18,19,20-tetranor-leukotriene E3 0
                                                          16-carboxy-Delta(13)-17,18,19,20-tetranor-leukotriene E4 + 0
                                                          18-carboxy-19,20-dinor-leukotriene E4 0
                                                          20-carboxyleukotriene E4 0
                                                          20-hydroxy-leukotriene E4 0
                                                          20-oxoleukotriene E4 0
                                                          N-acetylleukotriene E4 0
                                                          leukotriene E4 methyl ester 0
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