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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:glycylsarcosine
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Accession:CHEBI:155876 term browser browse the term
Definition:A dipeptide obtained by formal condensation of the carboxy group of glycine with the amino group of sarcosine.
Synonyms:exact_synonym: glycyl-N-methylglycine
 related_synonym: 2-(2-amino-N-methylacetamido)acetic acid;   Formula=C5H10N2O3;   Gly-Sar;   InChI=1S/C5H10N2O3/c1-7(3-5(9)10)4(8)2-6/h2-3,6H2,1H3,(H,9,10);   InChIKey=VYAMLSCELQQRAE-UHFFFAOYSA-N;   N-glycyl-N-methylglycine;   N-glycyl-Sar-OH;   N-glycylsarcosine;   SMILES=OC(=O)CN(C(CN)=O)C;   [(aminoacetyl)(methyl)amino]acetic acid;   glycyl-sarcosine
 xref: CAS:29816-01-1
 xref_mesh: MESH:C004194
 xref: PMID:17380260;   PMID:19201665;   PMID:23738724;   PMID:25260349;   PMID:26924013;   PMID:28594555;   PMID:29684535;   PMID:29797328;   PMID:30138575;   PMID:32024310;   PMID:32238712;   PMID:4708825;   PMID:477234;   PMID:514081;   PMID:520587;   Reaxys:1768450
 cyclic_relationship: is_tautomer_of CHEBI:155838


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glycylsarcosine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Slc15a1 solute carrier family 15 member 1 multiple interactions
affects transport
increases uptake
decreases activity
ISO
EXP
[Zinc results in decreased activity of SLC15A1 protein] which results in decreased uptake of glycylsarcosine; benazepril inhibits the reaction [SLC15A1 protein results in increased uptake of glycylsarcosine]; Cilazapril inhibits the reaction [SLC15A1 protein results in increased uptake of glycylsarcosine]; Fosinopril inhibits the reaction [SLC15A1 protein results in increased uptake of glycylsarcosine]; glycylsarcosine inhibits the reaction [SLC15A1 protein results in increased transport of Lisdexamfetamine Dimesylate]; moexipril inhibits the reaction [SLC15A1 protein results in increased uptake of glycylsarcosine]; Perindopril inhibits the reaction [SLC15A1 protein results in increased uptake of glycylsarcosine]; Quinapril inhibits the reaction [SLC15A1 protein results in increased uptake of glycylsarcosine]; quinaprilat inhibits the reaction [SLC15A1 protein results in increased uptake of glycylsarcosine]; Ramipril inhibits the reaction [SLC15A1 protein results in increased uptake of glycylsarcosine]; spirapril inhibits the reaction [SLC15A1 protein results in increased uptake of glycylsarcosine]; trandolapril inhibits the reaction [SLC15A1 protein results in increased uptake of glycylsarcosine]
SLC15A1 protein affects the transport of glycylsarcosine
glycylsarcosine results in decreased activity of SLC15A1 protein
CTD PMID:14567632, PMID:18713951, PMID:20628632, PMID:21240898, PMID:21341280 NCBI chr15:106,800,081...106,844,668
Ensembl chr15:106,800,081...106,844,426
JBrowse link
G Slc15a2 solute carrier family 15 member 2 multiple interactions
increases uptake
ISO
EXP
benazepril inhibits the reaction [SLC15A2 protein results in increased uptake of glycylsarcosine]; Enalapril inhibits the reaction [SLC15A2 protein results in increased uptake of glycylsarcosine]; Quinapril inhibits the reaction [SLC15A2 protein results in increased uptake of glycylsarcosine]; quinaprilat inhibits the reaction [SLC15A2 protein results in increased uptake of glycylsarcosine]; spirapril inhibits the reaction [SLC15A2 protein results in increased uptake of glycylsarcosine]
benazepril inhibits the reaction [SLC15A2 protein results in increased uptake of glycylsarcosine]; Cilazapril inhibits the reaction [SLC15A2 protein results in increased uptake of glycylsarcosine]; Fosinopril inhibits the reaction [SLC15A2 protein results in increased uptake of glycylsarcosine]; moexipril inhibits the reaction [SLC15A2 protein results in increased uptake of glycylsarcosine]; Perindopril inhibits the reaction [SLC15A2 protein results in increased uptake of glycylsarcosine]; Quinapril inhibits the reaction [SLC15A2 protein results in increased uptake of glycylsarcosine]; quinaprilat inhibits the reaction [SLC15A2 protein results in increased uptake of glycylsarcosine]; Ramipril inhibits the reaction [SLC15A2 protein results in increased uptake of glycylsarcosine]; spirapril inhibits the reaction [SLC15A2 protein results in increased uptake of glycylsarcosine]; trandolapril inhibits the reaction [SLC15A2 protein results in increased uptake of glycylsarcosine]
CTD PMID:18713951 NCBI chr11:66,932,664...66,961,708
Ensembl chr11:66,932,614...66,961,713
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19787
    chemical entity 19787
      group 19698
        organic group 18495
          amino-acid residue 9393
            peptide 9392
              oligopeptide 1196
                dipeptide 372
                  glycylsarcosine 2
Path 2
Term Annotations click to browse term
  CHEBI ontology 19787
    subatomic particle 19784
      composite particle 19784
        hadron 19784
          baryon 19784
            nucleon 19784
              atomic nucleus 19784
                atom 19784
                  main group element atom 19672
                    p-block element atom 19672
                      carbon group element atom 19574
                        carbon atom 19563
                          organic molecular entity 19563
                            organic group 18495
                              organic divalent group 18488
                                organodiyl group 18488
                                  carbonyl group 18391
                                    carbonyl compound 18391
                                      carboxylic acid 18061
                                        carboacyl group 17348
                                          univalent carboacyl group 17348
                                            carbamoyl group 17134
                                              carboxamide 17134
                                                peptide 9392
                                                  oligopeptide 1196
                                                    dipeptide 372
                                                      glycylsarcosine 2
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