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ONTOLOGY REPORT - ANNOTATIONS


Term:prostaglandin E2
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Accession:CHEBI:15551 term browser browse the term
Definition:Prostaglandin F2alpha in which the hydroxy group at position 9 has been oxidised to the corresponding ketone. Prostaglandin E2 is the most common and most biologically potent of mammalian prostaglandins.
Synonyms:exact_synonym: (5Z,13E,15S)-11alpha,15-dihydroxy-9-oxoprosta-5,13-dien-1-oic acid
 related_synonym: (15S)-prostaglandin E2;   (5Z,11alpha,13E,15S)-11,15-dihydroxy-9-oxoprosta-5,13-dien-1-oic acid;   (5Z,13E)-(15S)-11alpha,15-Dihydroxy-9-oxoprost-13-enoate;   (5Z,13E)-(15S)-11alpha,15-Dihydroxy-9-oxoprosta-5,13-dienoate;   (E,Z)-(1R,2R,3R)-7-(3-Hydroxy-2-((3S)-(3-hydroxy-1-octenyl))-5-oxocyclopentyl)-5-heptenoic acid;   (Z)-7-((1R,2R,3R)-3-hydroxy-2-((S,E)-3-hydroxyoct-1-enyl)-5-oxocyclopentyl)hept-5-enoic acid;   Dinoproston;   Dinoprostone;   Formula=C20H32O5;   InChI=1S/C20H32O5/c1-2-3-6-9-15(21)12-13-17-16(18(22)14-19(17)23)10-7-4-5-8-11-20(24)25/h4,7,12-13,15-17,19,21,23H,2-3,5-6,8-11,14H2,1H3,(H,24,25)/b7-4-,13-12+/t15-,16+,17+,19+/m0/s1;   InChIKey=XEYBRNLFEZDVAW-ARSRFYASSA-N;   PGE2;   Prepidil;   Propess;   Prostin E2;   SMILES=CCCCC[C@H](O)\\C=C\\[C@H]1[C@H](O)CC(=O)[C@@H]1C\\C=C/CCCC(O)=O;   dinoprostona;   dinoprostonum
 alt_id: CHEBI:10910;   CHEBI:10911;   CHEBI:114125;   CHEBI:26323;   CHEBI:4625;   CHEBI:8512
 xref: Beilstein:2224724;   CAS:363-24-6;   DrugBank:DB00917;   Drug_Central:913;   HMDB:HMDB0001220;   KEGG:C00584;   KEGG:D00079;   LIPID_MAPS_instance:LMFA03010003
 xref_mesh: MESH:D015232
 xref: MetaCyc:5Z13E-15S-1115-DIHYDROXY-9-OXOPROS;   PMID:24501112;   PMID:7224729;   PMID:7836930;   Patent:DE2011969;   Patent:GB851827;   Patent:NL6505799;   Patent:US3598858;   Reaxys:2224724;   Wikipedia:Prostaglandin_E2
 cyclic_relationship: is_conjugate_acid_of CHEBI:606564


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prostaglandin E2 term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Abcc4 ATP-binding cassette, sub-family C (CFTR/MRP), member 4 JBrowse link 14 118,482,692 118,707,856 RGD:6480464
G Ace angiotensin I converting enzyme (peptidyl-dipeptidase A) 1 JBrowse link 11 105,967,948 105,989,964 RGD:6480464
G Acta1 actin, alpha 1, skeletal muscle JBrowse link 8 123,891,758 123,894,775 RGD:6480464
G Acta2 actin, alpha 2, smooth muscle, aorta JBrowse link 19 34,240,336 34,255,585 RGD:6480464
G Adcyap1 adenylate cyclase activating polypeptide 1 JBrowse link 17 93,198,245 93,206,541 RGD:6480464
G Adm adrenomedullin JBrowse link 7 110,627,657 110,629,820 RGD:6480464
G Adrb2 adrenergic receptor, beta 2 JBrowse link 18 62,177,713 62,179,981 RGD:6480464
G Agt angiotensinogen (serpin peptidase inhibitor, clade A, member 8) JBrowse link 8 124,556,587 124,569,706 RGD:6480464
G Akr1b3 aldo-keto reductase family 1, member B3 (aldose reductase) JBrowse link 6 34,303,930 34,317,489 RGD:6480464
G Akt1 thymoma viral proto-oncogene 1 JBrowse link 12 112,653,821 112,674,884 RGD:6480464
G Alox15 arachidonate 15-lipoxygenase JBrowse link 11 70,344,147 70,390,538 RGD:6480464
G Anxa1 annexin A1 JBrowse link 19 20,373,434 20,390,671 RGD:6480464
G Apoa1 apolipoprotein A-I JBrowse link 9 46,228,630 46,230,469 RGD:6480464
G App amyloid beta (A4) precursor protein JBrowse link 16 84,952,666 85,175,255 RGD:6480464
G Aqp1 aquaporin 1 JBrowse link 6 55,336,299 55,348,555 RGD:6480464
G Areg amphiregulin JBrowse link 5 91,139,599 91,148,432 RGD:6480464
G Atf1 activating transcription factor 1 JBrowse link 15 100,227,859 100,261,248 RGD:6480464
G Atf3 activating transcription factor 3 JBrowse link 1 191,170,296 191,183,333 RGD:6480464
G Avp arginine vasopressin JBrowse link 2 130,580,620 130,582,588 RGD:6480464
G Bak1 BCL2-antagonist/killer 1 JBrowse link 17 27,019,812 27,028,627 RGD:6480464
G Bax BCL2-associated X protein JBrowse link 7 45,461,695 45,466,903 RGD:6480464
G Bcl2 B cell leukemia/lymphoma 2 JBrowse link 1 106,538,176 106,714,290 RGD:6480464
G Bcl2l1 BCL2-like 1 JBrowse link 2 152,758,732 152,833,803 RGD:6480464
G Birc3 baculoviral IAP repeat-containing 3 JBrowse link 9 7,847,468 7,873,205 RGD:6480464
G Birc5 baculoviral IAP repeat-containing 5 JBrowse link 11 117,849,237 117,855,743 RGD:6480464
G Calca calcitonin/calcitonin-related polypeptide, alpha JBrowse link 7 114,625,981 114,636,910 RGD:6480464
G Casp3 caspase 3 JBrowse link 8 46,617,291 46,639,698 RGD:6480464
G Casp8 caspase 8 JBrowse link 1 58,795,233 58,847,503 RGD:6480464
G Casp9 caspase 9 JBrowse link 4 141,793,612 141,815,978 RGD:6480464
G Cat catalase JBrowse link 2 103,453,904 103,485,153 RGD:6480464
G Cbs cystathionine beta-synthase JBrowse link 17 31,612,623 31,637,233 RGD:6480464
G Ccl12 chemokine (C-C motif) ligand 12 JBrowse link 11 82,101,845 82,103,399 RGD:6480464
G Ccl17 chemokine (C-C motif) ligand 17 JBrowse link 8 94,809,380 94,812,038 RGD:6480464
G Ccl2 chemokine (C-C motif) ligand 2 JBrowse link 11 82,035,577 82,037,452 RGD:6480464
G Ccl20 chemokine (C-C motif) ligand 20 JBrowse link 1 83,116,766 83,119,167 RGD:6480464
G Ccl22 chemokine (C-C motif) ligand 22 JBrowse link 8 94,745,684 94,751,388 RGD:6480464
G Ccl27a chemokine (C-C motif) ligand 27A JBrowse link 4 41,769,467 41,774,225 RGD:6480464
G Ccl3 chemokine (C-C motif) ligand 3 JBrowse link 11 83,647,843 83,649,378 RGD:6480464
G Ccl4 chemokine (C-C motif) ligand 4 JBrowse link 11 83,648,624 83,664,683 RGD:6480464
G Ccl5 chemokine (C-C motif) ligand 5 JBrowse link 11 83,525,778 83,530,518 RGD:6480464
G Ccn2 cellular communication network factor 2 JBrowse link 10 24,595,442 24,598,683 RGD:6480464
G Ccnd1 cyclin D1 JBrowse link 7 144,929,931 144,939,937 RGD:6480464
G Ccr5 chemokine (C-C motif) receptor 5 JBrowse link 9 124,121,543 124,127,183 RGD:6480464
G Ccr6 chemokine (C-C motif) receptor 6 JBrowse link 17 8,236,041 8,258,519 RGD:6480464
G Ccr7 chemokine (C-C motif) receptor 7 JBrowse link 11 99,144,199 99,155,077 RGD:6480464
G Cd68 CD68 antigen JBrowse link 11 69,664,213 69,666,170 RGD:6480464
G Cdh1 cadherin 1 JBrowse link 8 106,603,350 106,670,247 RGD:6480464
G Cebpa CCAAT/enhancer binding protein (C/EBP), alpha JBrowse link 7 35,119,293 35,121,928 RGD:6480464
G Cga glycoprotein hormones, alpha subunit JBrowse link 4 34,893,779 34,907,374 RGD:6480464
G Col10a1 collagen, type X, alpha 1 JBrowse link 10 34,389,981 34,397,085 RGD:6480464
G Col1a1 collagen, type I, alpha 1 JBrowse link 11 94,936,224 94,953,042 RGD:6480464
G Col2a1 collagen, type II, alpha 1 JBrowse link 15 97,975,602 98,004,724 RGD:6480464
G Cp ceruloplasmin JBrowse link 3 19,956,933 20,009,750 RGD:6480464
G Creb1 cAMP responsive element binding protein 1 JBrowse link 1 64,532,794 64,604,548 RGD:6480464
G Cryab crystallin, alpha B JBrowse link 9 50,745,951 50,756,636 RGD:6480464
G Csf2 colony stimulating factor 2 (granulocyte-macrophage) JBrowse link 11 54,247,270 54,249,899 RGD:6480464
G Ctnnb1 catenin (cadherin associated protein), beta 1 JBrowse link 9 120,933,400 120,960,507 RGD:6480464
G Cxcl10 chemokine (C-X-C motif) ligand 10 JBrowse link 5 92,346,638 92,348,889 RGD:6480464
G Cxcl15 chemokine (C-X-C motif) ligand 15 JBrowse link 5 90,794,534 90,803,067 RGD:6480464
G Cxcr4 chemokine (C-X-C motif) receptor 4 JBrowse link 1 128,588,199 128,592,299 RGD:6480464
G Cyp11a1 cytochrome P450, family 11, subfamily a, polypeptide 1 JBrowse link 9 57,998,024 58,027,031 RGD:6480464
G Cyp17a1 cytochrome P450, family 17, subfamily a, polypeptide 1 JBrowse link 19 46,667,165 46,673,000 RGD:6480464
G Cyp19a1 cytochrome P450, family 19, subfamily a, polypeptide 1 JBrowse link 9 54,165,937 54,268,164 RGD:6480464
G Cyp1b1 cytochrome P450, family 1, subfamily b, polypeptide 1 JBrowse link 17 79,706,940 79,715,061 RGD:6480464
G Cyp4a31 cytochrome P450, family 4, subfamily a, polypeptide 31 JBrowse link 4 115,563,627 115,579,015 RGD:6480464
G Ddit3 DNA-damage inducible transcript 3 JBrowse link 10 127,290,793 127,296,291 RGD:6480464
G Dusp1 dual specificity phosphatase 1 JBrowse link 17 26,505,591 26,508,472 RGD:6480464
G Edn1 endothelin 1 JBrowse link 13 42,301,476 42,307,990 RGD:6480464
G Egf epidermal growth factor JBrowse link 3 129,677,574 129,755,322 RGD:6480464
G Egfr epidermal growth factor receptor JBrowse link 11 16,752,203 16,913,907 RGD:6480464
G Ep300 E1A binding protein p300 JBrowse link 15 81,586,209 81,652,077 RGD:6480464
G Ephx2 epoxide hydrolase 2, cytoplasmic JBrowse link 14 66,084,372 66,124,522 RGD:6480464
G Ereg epiregulin JBrowse link 5 91,074,617 91,093,649 RGD:6480464
G Esr1 estrogen receptor 1 (alpha) JBrowse link 10 4,611,989 5,005,633 RGD:6480464
G Esrra estrogen related receptor, alpha JBrowse link 19 6,910,977 6,922,048 RGD:6480464
G F2 coagulation factor II JBrowse link 2 91,612,397 91,636,457 RGD:6480464
G Fas Fas (TNF receptor superfamily member 6) JBrowse link 19 34,290,647 34,327,775 RGD:6480464
G Fasl Fas ligand (TNF superfamily, member 6) JBrowse link 1 161,780,691 161,788,495 RGD:6480464
G Fasn fatty acid synthase JBrowse link 11 120,805,958 120,825,166 RGD:6480464
G Fcer2a Fc receptor, IgE, low affinity II, alpha polypeptide JBrowse link 8 3,680,280 3,694,174 RGD:6480464
G Fgf20 fibroblast growth factor 20 JBrowse link 8 40,279,166 40,286,953 RGD:6480464
G Fgf23 fibroblast growth factor 23 JBrowse link 6 127,072,902 127,082,296 RGD:6480464
G Fgf7 fibroblast growth factor 7 JBrowse link 2 126,034,658 126,091,185 RGD:6480464
G Fos FBJ osteosarcoma oncogene JBrowse link 12 85,473,890 85,477,274 RGD:6480464
G Gast gastrin JBrowse link 11 100,334,407 100,336,997 RGD:6480464
G Ghrl ghrelin JBrowse link 6 113,716,119 113,719,911 RGD:6480464
G Glra3 glycine receptor, alpha 3 subunit JBrowse link 8 55,940,418 56,130,070 RGD:6480464
G Gpt glutamic pyruvic transaminase, soluble JBrowse link 15 76,696,726 76,699,675 RGD:6480464
G Gpx1 glutathione peroxidase 1 JBrowse link 9 108,339,080 108,340,342 RGD:6480464
G Gpx2 glutathione peroxidase 2 JBrowse link 12 76,792,335 76,795,554 RGD:6480464
G Grin2a glutamate receptor, ionotropic, NMDA2A (epsilon 1) JBrowse link 16 9,567,901 9,996,083 RGD:6480464
G Grin2d glutamate receptor, ionotropic, NMDA2D (epsilon 4) JBrowse link 7 45,831,883 45,871,194 RGD:6480464
G Gsk3a glycogen synthase kinase 3 alpha JBrowse link 7 25,228,258 25,237,851 RGD:6480464
G Gsk3b glycogen synthase kinase 3 beta JBrowse link 16 38,089,001 38,246,084 RGD:6480464
G Gstm2 glutathione S-transferase, mu 2 JBrowse link 3 107,981,702 107,986,420 RGD:6480464
G Gstm5 glutathione S-transferase, mu 5 JBrowse link 3 107,895,854 107,898,685 RGD:6480464
G Hcrt hypocretin JBrowse link 11 100,761,693 100,762,931 RGD:6480464
G Hgf hepatocyte growth factor JBrowse link 5 16,553,495 16,619,439 RGD:6480464
G Hif1a hypoxia inducible factor 1, alpha subunit JBrowse link 12 73,901,324 73,947,554 RGD:6480464
G Hk2 hexokinase 2 JBrowse link 6 82,725,025 82,774,454 RGD:6480464
G Hmox1 heme oxygenase 1 JBrowse link 8 75,093,618 75,100,593 RGD:6480464
G Hpgd hydroxyprostaglandin dehydrogenase 15 (NAD) JBrowse link 8 56,294,552 56,321,046 RGD:6480464
G Hrh2 histamine receptor H2 JBrowse link 13 54,191,970 54,236,182 RGD:6480464
G Hsd11b1 hydroxysteroid 11-beta dehydrogenase 1 JBrowse link 1 193,221,640 193,264,049 RGD:6480464
G Hsd11b2 hydroxysteroid 11-beta dehydrogenase 2 JBrowse link 8 105,518,746 105,523,988 RGD:6480464
G Icam1 intercellular adhesion molecule 1 JBrowse link 9 21,015,940 21,028,814 RGD:6480464
G Ifng interferon gamma JBrowse link 10 118,441,046 118,445,894 RGD:6480464
G Ighe Immunoglobulin heavy constant epsilon JBrowse link 12 113,269,263 113,273,248 RGD:6480464
G Il10 interleukin 10 JBrowse link 1 131,019,845 131,024,970 RGD:6480464
G Il11 interleukin 11 JBrowse link 7 4,772,373 4,782,907 RGD:6480464
G Il12a interleukin 12a JBrowse link 3 68,690,644 68,698,550 RGD:6480464
G Il12b interleukin 12b JBrowse link 11 44,400,063 44,414,677 RGD:6480464
G Il12rb1 interleukin 12 receptor, beta 1 JBrowse link 8 70,808,360 70,823,542 RGD:6480464
G Il12rb2 interleukin 12 receptor, beta 2 JBrowse link 6 67,285,986 67,376,293 RGD:6480464
G Il13 interleukin 13 JBrowse link 11 53,631,323 53,634,702 RGD:6480464
G Il17f interleukin 17F JBrowse link 1 20,777,146 20,785,274 RGD:6480464
G Il17ra interleukin 17 receptor A JBrowse link 6 120,463,181 120,483,731 RGD:6480464
G Il1a interleukin 1 alpha JBrowse link 2 129,299,609 129,310,186 RGD:6480464
G Il1b interleukin 1 beta JBrowse link 2 129,364,569 129,371,164 RGD:6480464
G Il1r1 interleukin 1 receptor, type I JBrowse link 1 40,222,480 40,316,201 RGD:6480464
G Il1rn interleukin 1 receptor antagonist JBrowse link 2 24,336,860 24,351,491 RGD:6480464
G Il2 interleukin 2 JBrowse link 3 37,120,713 37,125,954 RGD:6480464
G Il22 interleukin 22 JBrowse link 10 118,204,584 118,210,047 RGD:6480464
G Il23a interleukin 23, alpha subunit p19 JBrowse link 10 128,296,140 128,298,084 RGD:6480464
G Il2ra interleukin 2 receptor, alpha chain JBrowse link 2 11,642,792 11,693,194 RGD:6480464
G Il2rg interleukin 2 receptor, gamma chain JBrowse link X 101,264,385 101,268,255 RGD:6480464
G Il4 interleukin 4 JBrowse link 11 53,612,460 53,618,665 RGD:6480464
G Il5 interleukin 5 JBrowse link 11 53,720,794 53,725,103 RGD:6480464
G Il6 interleukin 6 JBrowse link 5 30,013,114 30,019,975 RGD:6480464
G Itga2 integrin alpha 2 JBrowse link 13 114,833,081 114,932,100 RGD:6480464
G Itgb1 integrin beta 1 (fibronectin receptor beta) JBrowse link 8 128,685,654 128,733,579 RGD:6480464
G Jak3 Janus kinase 3 JBrowse link 8 71,676,383 71,690,577 RGD:6480464
G Kat2b K(lysine) acetyltransferase 2B JBrowse link 17 53,566,774 53,672,721 RGD:6480464
G Kng2 kininogen 2 JBrowse link 16 22,985,852 23,029,101 RGD:6480464
G Ldha lactate dehydrogenase A JBrowse link 7 46,842,274 46,855,627 RGD:6480464
G Lep leptin JBrowse link 6 29,060,221 29,073,876 RGD:6480464
G Map3k8 mitogen-activated protein kinase kinase kinase 8 JBrowse link 18 4,331,325 4,352,953 RGD:6480464
G Mapk1 mitogen-activated protein kinase 1 JBrowse link 16 16,983,382 17,047,453 RGD:6480464
G Mapk14 mitogen-activated protein kinase 14 JBrowse link 17 28,691,342 28,748,405 RGD:6480464
G Mapk3 mitogen-activated protein kinase 3 JBrowse link 7 126,759,626 126,765,816 RGD:6480464
G Mapk8 mitogen-activated protein kinase 8 JBrowse link 14 33,377,898 33,447,353 RGD:6480464
G Mmp2 matrix metallopeptidase 2 JBrowse link 8 92,827,290 92,853,421 RGD:6480464
G Mmp3 matrix metallopeptidase 3 JBrowse link 9 7,445,822 7,455,975 RGD:6480464
G Mmp9 matrix metallopeptidase 9 JBrowse link 2 164,940,326 164,955,850 RGD:6480464
G Mpo myeloperoxidase JBrowse link 11 87,793,784 87,804,412 RGD:6480464
G Mtor mechanistic target of rapamycin kinase JBrowse link 4 148,448,582 148,557,685 RGD:6480464
G Muc1 mucin 1, transmembrane JBrowse link 3 89,229,056 89,233,381 RGD:6480464
G Myc myelocytomatosis oncogene JBrowse link 15 61,985,341 61,990,361 RGD:6480464
G Myh7 myosin, heavy polypeptide 7, cardiac muscle, beta JBrowse link 14 54,970,684 54,994,626 RGD:6480464
G Nfe2l2 nuclear factor, erythroid derived 2, like 2 JBrowse link 2 75,675,513 75,704,663 RGD:6480464
G Nfkb1 nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105 JBrowse link 3 135,584,655 135,691,969 RGD:6480464
G Nfkbia nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, alpha JBrowse link 12 55,489,409 55,492,647 RGD:6480464
G Ngf nerve growth factor JBrowse link 3 102,469,919 102,521,013 RGD:6480464
G Nos2 nitric oxide synthase 2, inducible JBrowse link 11 78,920,787 78,960,226 RGD:6480464
G Nppa natriuretic peptide type A JBrowse link 4 148,000,722 148,002,074 RGD:6480464
G Nppb natriuretic peptide type B JBrowse link 4 147,985,786 147,987,205 RGD:6480464
G Nr2f2 nuclear receptor subfamily 2, group F, member 2 JBrowse link 7 70,351,946 70,366,746 RGD:6480464
G Nr4a2 nuclear receptor subfamily 4, group A, member 2 JBrowse link 2 57,106,830 57,124,003 RGD:6480464
G Nr5a1 nuclear receptor subfamily 5, group A, member 1 JBrowse link 2 38,692,656 38,714,542 RGD:6480464
G Nrg1 neuregulin 1 JBrowse link 8 31,807,452 32,891,609 RGD:6480464
G Orm1 orosomucoid 1 JBrowse link 4 63,344,556 63,348,163 RGD:6480464
G Osmr oncostatin M receptor JBrowse link 15 6,813,568 6,874,968 RGD:6480464
G Park7 Parkinson disease (autosomal recessive, early onset) 7 JBrowse link 4 150,897,133 150,909,921 RGD:6480464
G Parp1 poly (ADP-ribose) polymerase family, member 1 JBrowse link 1 180,568,891 180,600,999 RGD:6480464
G Pdgfa platelet derived growth factor, alpha JBrowse link 5 138,976,014 139,000,792 RGD:6480464
G Pklr pyruvate kinase liver and red blood cell JBrowse link 3 89,136,122 89,146,815 RGD:6480464
G Pla2g2a phospholipase A2, group IIA (platelets, synovial fluid) JBrowse link 4 138,831,857 138,835,189 RGD:6480464
G Pla2g4a phospholipase A2, group IVA (cytosolic, calcium-dependent) JBrowse link 1 149,829,618 149,961,290 RGD:6480464
G Pla2g5 phospholipase A2, group V JBrowse link 4 138,799,247 138,863,562 RGD:6480464
G Pld1 phospholipase D1 JBrowse link 3 27,938,459 28,133,362 RGD:6480464
G Pld2 phospholipase D2 JBrowse link 11 70,539,492 70,558,110 RGD:6480464
G Ppard peroxisome proliferator activator receptor delta JBrowse link 17 28,232,754 28,301,469 RGD:6480464
G Ppp1r9b protein phosphatase 1, regulatory subunit 9B JBrowse link 11 94,991,212 95,006,898 RGD:6480464
G Prkaca protein kinase, cAMP dependent, catalytic, alpha JBrowse link 8 83,972,978 83,996,444 RGD:6480464
G Prkce protein kinase C, epsilon JBrowse link 17 86,167,785 86,657,919 RGD:6480464
G Prl prolactin JBrowse link 13 27,057,570 27,065,204 RGD:6480464
G Prodh proline dehydrogenase JBrowse link 16 18,071,726 18,089,283 RGD:6480464
G Psen2 presenilin 2 JBrowse link 1 180,227,004 180,263,467 RGD:6480464
G Ptgdr prostaglandin D receptor JBrowse link 14 44,851,235 44,859,375 RGD:6480464
G Ptger1 prostaglandin E receptor 1 (subtype EP1) JBrowse link 8 83,666,644 83,672,756 RGD:6480464
G Ptger2 prostaglandin E receptor 2 (subtype EP2) JBrowse link 14 44,988,111 45,003,820 RGD:6480464
G Ptger3 prostaglandin E receptor 3 (subtype EP3) JBrowse link 3 157,566,819 157,644,758 RGD:6480464
G Ptger4 prostaglandin E receptor 4 (subtype EP4) JBrowse link 15 5,233,399 5,244,187 RGD:6480464
G Ptges prostaglandin E synthase JBrowse link 2 30,889,471 30,931,020 RGD:6480464
G Ptges2 prostaglandin E synthase 2 JBrowse link 2 32,395,890 32,402,740 RGD:6480464
G Ptgs1 prostaglandin-endoperoxide synthase 1 JBrowse link 2 36,216,742 36,258,593 RGD:6480464
G Ptgs2 prostaglandin-endoperoxide synthase 2 JBrowse link 1 150,100,031 150,108,234 RGD:6480464
G Rela v-rel reticuloendotheliosis viral oncogene homolog A (avian) JBrowse link 19 5,637,442 5,648,134 RGD:6480464
G Ren1 renin 1 structural JBrowse link 1 133,350,674 133,360,320 RGD:6480464
G Retn resistin JBrowse link 8 3,655,770 3,659,818 RGD:6480464
G Rorc RAR-related orphan receptor gamma JBrowse link 3 94,372,794 94,398,276 RGD:6480464
G Rps6 ribosomal protein S6 JBrowse link 4 86,854,099 86,857,367 RGD:6480464
G Runx2 runt related transcription factor 2 JBrowse link 17 44,495,987 44,814,797 RGD:6480464
G Sirt1 sirtuin 1 JBrowse link 10 63,319,005 63,339,035 RGD:6480464
G Slc16a3 solute carrier family 16 (monocarboxylic acid transporters), member 3 JBrowse link 11 120,948,484 120,959,000 RGD:6480464
G Slc22a22 solute carrier family 22 (organic cation transporter), member 22 JBrowse link 15 57,243,767 57,477,625 RGD:6480464
G Slc22a6 solute carrier family 22 (organic anion transporter), member 6 JBrowse link 19 8,617,996 8,628,299 RGD:6480464
G Slc22a7 solute carrier family 22 (organic anion transporter), member 7 JBrowse link 17 46,432,185 46,438,477 RGD:6480464
G Slc22a8 solute carrier family 22 (organic anion transporter), member 8 JBrowse link 19 8,591,254 8,611,835 RGD:6480464
G Slc2a1 solute carrier family 2 (facilitated glucose transporter), member 1 JBrowse link 4 119,108,745 119,137,330 RGD:6480464
G Slco2a1 solute carrier organic anion transporter family, member 2a1 JBrowse link 9 103,007,061 103,096,002 RGD:6480464
G Sod2 superoxide dismutase 2, mitochondrial JBrowse link 17 13,007,839 13,018,119 RGD:6480464
G Sox2 SRY (sex determining region Y)-box 2 JBrowse link 3 34,649,995 34,652,461 RGD:6480464
G Sox9 SRY (sex determining region Y)-box 9 JBrowse link 11 112,782,210 112,787,757 RGD:6480464
G Star steroidogenic acute regulatory protein JBrowse link 8 25,808,474 25,815,982 RGD:6480464
G Stat3 signal transducer and activator of transcription 3 JBrowse link 11 100,886,806 100,939,594 RGD:6480464
G Tac1 tachykinin 1 JBrowse link 6 7,555,061 7,562,978 RGD:6480464
G Tbx21 T-box 21 JBrowse link 11 97,098,007 97,115,331 RGD:6480464
G Tfrc transferrin receptor JBrowse link 16 32,608,896 32,632,794 RGD:6480464
G Tgfb1 transforming growth factor, beta 1 JBrowse link 7 25,687,002 25,705,077 RGD:6480464
G Tgfb2 transforming growth factor, beta 2 JBrowse link 1 186,622,787 186,709,697 RGD:6480464
G Tgfb3 transforming growth factor, beta 3 JBrowse link 12 86,056,743 86,079,041 RGD:6480464
G Tgfbr1 transforming growth factor, beta receptor I JBrowse link 4 47,353,222 47,414,926 RGD:6480464
G Tgfbr2 transforming growth factor, beta receptor II JBrowse link 9 116,087,695 116,175,363 RGD:6480464
G Thrsp thyroid hormone responsive JBrowse link 7 97,412,933 97,417,550 RGD:6480464
G Timp1 tissue inhibitor of metalloproteinase 1 JBrowse link X 20,870,166 20,874,737 RGD:6480464
G Tlr2 toll-like receptor 2 JBrowse link 3 83,836,272 83,841,824 RGD:6480464
G Tnf tumor necrosis factor JBrowse link 17 35,199,367 35,202,007 RGD:6480464
G Tnfrsf11b tumor necrosis factor receptor superfamily, member 11b (osteoprotegerin) JBrowse link 15 54,250,619 54,278,484 RGD:6480464
G Tnfrsf1a tumor necrosis factor receptor superfamily, member 1a JBrowse link 6 125,349,723 125,362,483 RGD:6480464
G Trpc7 transient receptor potential cation channel, subfamily C, member 7 JBrowse link 13 56,773,098 56,895,968 RGD:6480464
G Trpv4 transient receptor potential cation channel, subfamily V, member 4 JBrowse link 5 114,622,152 114,658,435 RGD:6480464
G Ucp1 uncoupling protein 1 (mitochondrial, proton carrier) JBrowse link 8 83,290,348 83,298,456 RGD:6480464
G Ugt1a1 UDP glucuronosyltransferase 1 family, polypeptide A1 JBrowse link 1 88,211,959 88,220,002 RGD:6480464
G Vasp vasodilator-stimulated phosphoprotein JBrowse link 7 19,256,929 19,271,854 RGD:6480464
G Vegfa vascular endothelial growth factor A JBrowse link 17 46,016,993 46,032,377 RGD:6480464
G Vegfc vascular endothelial growth factor C JBrowse link 8 54,077,532 54,186,454 RGD:6480464
G Vgf VGF nerve growth factor inducible JBrowse link 5 137,025,301 137,033,351 RGD:6480464
G Wt1 Wilms tumor 1 homolog JBrowse link 2 105,126,529 105,173,614 RGD:6480464
13,14-dihydro-15-oxo-prostaglandin E2 term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ptgr1 prostaglandin reductase 1 JBrowse link 4 58,965,590 58,987,131 RGD:6480464
15-dehydro-prostaglandin E2 term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Hpgd hydroxyprostaglandin dehydrogenase 15 (NAD) JBrowse link 8 56,294,552 56,321,046 RGD:6480464
G Ptgr1 prostaglandin reductase 1 JBrowse link 4 58,965,590 58,987,131 RGD:6480464
8-epi-prostaglandin E2 term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ptger4 prostaglandin E receptor 4 (subtype EP4) JBrowse link 15 5,233,399 5,244,187 RGD:6480464

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 21260
    role 21244
      application 20679
        pharmaceutical 20060
          drug 20060
            oxytocic 245
              prostaglandin E2 231
                13,14-dihydro-15-oxo-prostaglandin E2 1
                15-dehydro-prostaglandin E2 2
                2-[(5Z,13E,15S)-11alpha,15-dihydroxy-9-oxoprosta-5,13-dien-1-oyl]-sn-glycero-3-phosphocholine 0
                2-[(5Z,13E,15S)-11alpha,15-dihydroxy-9-oxoprosta-5,13-dien-1-oyl]-sn-glycero-3-phosphoethanolamine 0
                20-hydroxyprostaglandin E2 0
                8-epi-prostaglandin E2 1
                nitroproston 0
                prostaglandin E2 1-glyceryl ester 0
                prostaglandin E2 2-glyceryl ester 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 21260
    subatomic particle 21256
      composite particle 21256
        hadron 21256
          baryon 21256
            nucleon 21256
              atomic nucleus 21256
                atom 21256
                  main group element atom 21122
                    p-block element atom 21122
                      carbon group element atom 20893
                        carbon atom 20784
                          organic molecular entity 20784
                            organic group 19177
                              organic divalent group 19167
                                organodiyl group 19167
                                  carbonyl group 19137
                                    carbonyl compound 19137
                                      carboxylic acid 18818
                                        monocarboxylic acid 18014
                                          fatty acid 16418
                                            fatty acid derivative 1017
                                              icosanoid 455
                                                prostanoid 397
                                                  prostaglandin 392
                                                    prostaglandins E 234
                                                      prostaglandin E2 231
                                                        13,14-dihydro-15-oxo-prostaglandin E2 1
                                                        15-dehydro-prostaglandin E2 2
                                                        2-[(5Z,13E,15S)-11alpha,15-dihydroxy-9-oxoprosta-5,13-dien-1-oyl]-sn-glycero-3-phosphocholine 0
                                                        2-[(5Z,13E,15S)-11alpha,15-dihydroxy-9-oxoprosta-5,13-dien-1-oyl]-sn-glycero-3-phosphoethanolamine 0
                                                        20-hydroxyprostaglandin E2 0
                                                        8-epi-prostaglandin E2 1
                                                        nitroproston 0
                                                        prostaglandin E2 1-glyceryl ester 0
                                                        prostaglandin E2 2-glyceryl ester 0
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.