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ONTOLOGY REPORT - ANNOTATIONS


Term:prostaglandin E1
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Accession:CHEBI:15544 term browser browse the term
Definition:A prostaglandins E that has formula C20H34O5.
Synonyms:exact_synonym: (13E,15S)-11alpha,15-dihydroxy-9-oxoprost-13-en-1-oic acid
 related_synonym: (11alpha,13E,15S)-11,15-dihydroxy-9-oxoprost-13-en-1-oic acid;   (13E)-(15S)-11alpha,15-Dihydroxy-9-oxoprost-13-enoate;   11alpha,15alpha-dihydroxy-9-oxo-13-trans-prostenoic acid;   Alprostadil;   Befar;   Caverject;   Edex;   Formula=C20H34O5;   InChI=1S/C20H34O5/c1-2-3-6-9-15(21)12-13-17-16(18(22)14-19(17)23)10-7-4-5-8-11-20(24)25/h12-13,15-17,19,21,23H,2-11,14H2,1H3,(H,24,25)/b13-12+/t15-,16+,17+,19+/m0/s1;   InChIKey=GMVPRGQOIOIIMI-DWKJAMRDSA-N;   Muse;   PGE-1;   PGE1;   Prostin VR;   SMILES=CCCCC[C@H](O)\\C=C\\[C@H]1[C@H](O)CC(=O)[C@@H]1CCCCCCC(O)=O;   alprostadilum
 alt_id: CHEBI:10820;   CHEBI:142;   CHEBI:26322
 xref: Beilstein:2061617 "Beilstein";   CAS:745-65-3 "ChemIDplus";   CAS:745-65-3 "KEGG COMPOUND";   DrugBank:DB00770;   Drug_Central:138 "DrugCentral";   HMDB:HMDB0001442;   KEGG:C04741;   KEGG:D00180;   LIPID_MAPS_instance:LMFA03010134 "LIPID MAPS"
 xref_mesh: MESH:D000527
 xref: PMID:15295081 "Europe PMC";   PMID:18176061 "Europe PMC";   PMID:7732902 "Europe PMC";   Reaxys:2061617 "Reaxys";   Wikipedia:Prostaglandin_E1
 cyclic_relationship: is_conjugate_acid_of CHEBI:57397


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prostaglandin E1 term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Abcc4 ATP binding cassette subfamily C member 4 JBrowse link 15 103,695,415 103,927,980 RGD:6480464
G Adrb2 adrenoceptor beta 2 JBrowse link 18 57,513,792 57,515,834 RGD:6480464
G Agt angiotensinogen JBrowse link 19 57,321,594 57,333,460 RGD:6480464
G Casp3 caspase 3 JBrowse link 16 48,845,011 48,863,249 RGD:6480464
G Cxcl2 C-X-C motif chemokine ligand 2 JBrowse link 14 18,731,346 18,733,391 RGD:6480464
G Il23a interleukin 23 subunit alpha JBrowse link 7 2,710,609 2,712,723 RGD:6480464
G Il6 interleukin 6 JBrowse link 4 3,043,231 3,047,807 RGD:6480464
G Nfkbia NFKB inhibitor alpha JBrowse link 6 76,267,227 76,270,457 RGD:6480464
G Nos2 nitric oxide synthase 2 JBrowse link 10 66,188,290 66,221,621 RGD:6480464
G Nppa natriuretic peptide A JBrowse link 5 164,808,407 164,809,716 RGD:6480464
G Nppb natriuretic peptide B JBrowse link 5 164,796,176 164,797,538 RGD:6480464
G Ptgdr prostaglandin D2 receptor JBrowse link 15 19,195,606 19,196,508 RGD:6480464
G Rela RELA proto-oncogene, NF-kB subunit JBrowse link 1 220,992,770 221,003,249 RGD:6480464
G Ren renin JBrowse link 13 50,502,724 50,513,953 RGD:6480464
G Timp1 TIMP metallopeptidase inhibitor 1 JBrowse link X 1,364,771 1,369,451 RGD:6480464
G Tnf tumor necrosis factor JBrowse link 20 5,189,382 5,192,000 RGD:6480464
G Tnfrsf11b TNF receptor superfamily member 11B JBrowse link 7 93,798,580 93,826,586 RGD:6480464
G Vasp vasodilator-stimulated phosphoprotein JBrowse link 1 80,170,608 80,185,882 RGD:6480464
13,14-dihydro-15-oxoprostaglandin E1 term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ptgr1 prostaglandin reductase 1 JBrowse link 5 76,110,746 76,129,361 RGD:6480464

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19679
    role 19623
      application 19246
        pharmaceutical 19108
          drug 19108
            cardiovascular drug 7559
              vasodilator agent 5675
                prostaglandin E1 19
                  13,14-dihydro-15-oxoprostaglandin E1 1
                  15-dehydro-prostaglandin E1 0
                  20-hydroxyprostaglandin E1 0
                  6-oxoprostaglandin E1 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19679
    subatomic particle 19675
      composite particle 19675
        hadron 19675
          baryon 19675
            nucleon 19675
              atomic nucleus 19675
                atom 19675
                  main group element atom 19555
                    p-block element atom 19555
                      carbon group element atom 19438
                        carbon atom 19430
                          organic molecular entity 19430
                            organic group 18351
                              organic divalent group 18340
                                organodiyl group 18340
                                  carbonyl group 18225
                                    carbonyl compound 18225
                                      carboxylic acid 17930
                                        monocarboxylic acid 17259
                                          fatty acid 15815
                                            fatty acid derivative 1008
                                              icosanoid 450
                                                prostanoid 393
                                                  prostaglandin 388
                                                    prostaglandins E 231
                                                      prostaglandin E1 19
                                                        13,14-dihydro-15-oxoprostaglandin E1 1
                                                        15-dehydro-prostaglandin E1 0
                                                        20-hydroxyprostaglandin E1 0
                                                        6-oxoprostaglandin E1 0
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.