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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:malonyl-CoA
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Accession:CHEBI:15531 term browser browse the term
Definition:The S-malonyl derivative of coenzyme A.
Synonyms:exact_synonym: 3'-phosphoadenosine 5'-{3-[(3R)-4-{[3-({2-[(3-carboxyacetyl)sulfanyl]ethyl}amino)-3-oxopropyl]amino}-3-hydroxy-2,2-dimethyl-4-oxobutyl] dihydrogen diphosphate}
 related_synonym: Coenzyme A, S-(hydrogen propanedioate);   Formula=C24H38N7O19P3S;   InChI=1S/C24H38N7O19P3S/c1-24(2,19(37)22(38)27-4-3-13(32)26-5-6-54-15(35)7-14(33)34)9-47-53(44,45)50-52(42,43)46-8-12-18(49-51(39,40)41)17(36)23(48-12)31-11-30-16-20(25)28-10-29-21(16)31/h10-12,17-19,23,36-37H,3-9H2,1-2H3,(H,26,32)(H,27,38)(H,33,34)(H,42,43)(H,44,45)(H2,25,28,29)(H2,39,40,41)/t12-,17-,18-,19+,23-/m1/s1;   InChIKey=LTYOQGRJFJAKNA-DVVLENMVSA-N;   Malonyl coenzyme A;   S-(Hydrogen malonyl)coenzyme A;   SMILES=CC(C)(COP(O)(=O)OP(O)(=O)OC[C@H]1O[C@H]([C@H](O)[C@@H]1OP(O)(O)=O)n1cnc2c(N)ncnc12)[C@@H](O)C(=O)NCCC(=O)NCCSC(=O)CC(O)=O
 alt_id: CHEBI:14565;   CHEBI:25135;   CHEBI:43979;   CHEBI:6661
 xref: CAS:524-14-1;   DrugBank:DB04524;   KEGG:C00083;   KNApSAcK:C00007260;   LIPID_MAPS_instance:LMFA07050031
 xref_mesh: MESH:D008316
 xref: MetaCyc:MALONYL-COA;   PDBeChem:MLC;   PMID:11117381;   PMID:11934665;   PMID:16651524;   PMID:17126822;   PMID:17522981;   PMID:18294446;   PMID:21199367;   PMID:21508288;   PMID:21763447;   Reaxys:78309;   Wikipedia:Malonyl-CoA
 cyclic_relationship: is_conjugate_acid_of CHEBI:57384



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malonyl-CoA term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mlycd malonyl-CoA decarboxylase multiple interactions ISO PPARA protein promotes the reaction [MLYCD protein results in decreased abundance of Malonyl Coenzyme A] CTD PMID:14641110 NCBI chr19:47,447,931...47,463,794
Ensembl chr19:47,447,970...47,463,793
JBrowse link
G Ppara peroxisome proliferator activated receptor alpha multiple interactions ISO PPARA protein promotes the reaction [MLYCD protein results in decreased abundance of Malonyl Coenzyme A] CTD PMID:14641110 NCBI chr 7:116,832,405...116,900,878
Ensembl chr 7:116,832,756...116,895,346
JBrowse link

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  CHEBI ontology 20050
    role 20001
      biological role 20000
        biochemical role 19624
          metabolite 19605
            malonyl-CoA 2
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  CHEBI ontology 20050
    subatomic particle 20048
      composite particle 20048
        hadron 20048
          baryon 20048
            nucleon 20048
              atomic nucleus 20048
                atom 20048
                  main group element atom 19948
                    p-block element atom 19948
                      chalcogen 19673
                        oxygen atom 19644
                          oxygen molecular entity 19644
                            hydroxides 19375
                              oxoacid 18675
                                pnictogen oxoacid 10750
                                  phosphorus oxoacid 9743
                                    phosphoric acids 8547
                                      phosphoric acid 8547
                                        phosphoric acid derivative 8248
                                          phosphate 8248
                                            organic phosphate 8247
                                              carbohydrate phosphate 1742
                                                phospho sugar 1666
                                                  aldose phosphate 1664
                                                    aldopentose phosphate 1656
                                                      ribose phosphate 1651
                                                        ribonucleotide 1614
                                                          purine ribonucleotide 1587
                                                            adenyl ribonucleotide 1291
                                                              adenosine phosphate 281
                                                                adenosine 5'-phosphate 280
                                                                  ADP 87
                                                                    coenzyme A 28
                                                                      acyl-CoA 28
                                                                        malonyl-CoAs 2
                                                                          malonyl-CoA 2
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