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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:malonyl-CoA
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Accession:CHEBI:15531 term browser browse the term
Definition:The S-malonyl derivative of coenzyme A.
Synonyms:exact_synonym: 3'-phosphoadenosine 5'-{3-[(3R)-4-{[3-({2-[(3-carboxyacetyl)sulfanyl]ethyl}amino)-3-oxopropyl]amino}-3-hydroxy-2,2-dimethyl-4-oxobutyl] dihydrogen diphosphate}
 related_synonym: Coenzyme A, S-(hydrogen propanedioate);   Formula=C24H38N7O19P3S;   InChI=1S/C24H38N7O19P3S/c1-24(2,19(37)22(38)27-4-3-13(32)26-5-6-54-15(35)7-14(33)34)9-47-53(44,45)50-52(42,43)46-8-12-18(49-51(39,40)41)17(36)23(48-12)31-11-30-16-20(25)28-10-29-21(16)31/h10-12,17-19,23,36-37H,3-9H2,1-2H3,(H,26,32)(H,27,38)(H,33,34)(H,42,43)(H,44,45)(H2,25,28,29)(H2,39,40,41)/t12-,17-,18-,19+,23-/m1/s1;   InChIKey=LTYOQGRJFJAKNA-DVVLENMVSA-N;   Malonyl coenzyme A;   S-(Hydrogen malonyl)coenzyme A;   SMILES=CC(C)(COP(O)(=O)OP(O)(=O)OC[C@H]1O[C@H]([C@H](O)[C@@H]1OP(O)(O)=O)n1cnc2c(N)ncnc12)[C@@H](O)C(=O)NCCC(=O)NCCSC(=O)CC(O)=O
 alt_id: CHEBI:14565;   CHEBI:25135;   CHEBI:43979;   CHEBI:6661
 xref: CAS:524-14-1;   DrugBank:DB04524;   KEGG:C00083;   KNApSAcK:C00007260;   LIPID_MAPS_instance:LMFA07050031
 xref_mesh: MESH:D008316
 xref: MetaCyc:MALONYL-COA;   PDBeChem:MLC;   PMID:11117381;   PMID:11934665;   PMID:16651524;   PMID:17126822;   PMID:17522981;   PMID:18294446;   PMID:21199367;   PMID:21508288;   PMID:21763447;   Reaxys:78309;   Wikipedia:Malonyl-CoA
 cyclic_relationship: is_conjugate_acid_of CHEBI:57384


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malonyl-CoA term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mlycd malonyl-CoA decarboxylase multiple interactions ISO PPARA protein promotes the reaction [MLYCD protein results in decreased abundance of Malonyl Coenzyme A] CTD PMID:14641110 NCBI chr19:47,447,931...47,463,794
Ensembl chr19:47,447,970...47,463,793 		JBrowse link
G Ppara peroxisome proliferator activated receptor alpha multiple interactions ISO PPARA protein promotes the reaction [MLYCD protein results in decreased abundance of Malonyl Coenzyme A] CTD PMID:14641110 NCBI chr 7:116,832,405...116,900,878
Ensembl chr 7:116,832,756...116,895,346 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19853
    role 19825
      biological role 19823
        biochemical role 19534
          metabolite 19521
            malonyl-CoA 2
Path 2
Term Annotations click to browse term
  CHEBI ontology 19853
    subatomic particle 19851
      composite particle 19851
        hadron 19851
          baryon 19851
            nucleon 19851
              atomic nucleus 19851
                atom 19851
                  main group element atom 19797
                    p-block element atom 19797
                      chalcogen 19547
                        oxygen atom 19520
                          oxygen molecular entity 19520
                            hydroxides 19325
                              oxoacid 18764
                                pnictogen oxoacid 14901
                                  phosphorus oxoacid 14490
                                    phosphoric acids 13927
                                      phosphoric acid 13927
                                        phosphoric acid derivative 13833
                                          phosphate 13832
                                            organic phosphate 13832
                                              carbohydrate phosphate 1865
                                                phospho sugar 1710
                                                  aldose phosphate 1707
                                                    aldopentose phosphate 1699
                                                      ribose phosphate 1694
                                                        ribonucleotide 1656
                                                          purine ribonucleotide 1613
                                                            adenyl ribonucleotide 1305
                                                              adenosine phosphate 296
                                                                adenosine 5'-phosphate 295
                                                                  ADP 88
                                                                    3'-phosphate-adenosine-5'-diphosphate 29
                                                                      coenzyme A 29
                                                                        acyl-CoA 29
                                                                          malonyl-CoAs 2
                                                                            malonyl-CoA 2
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