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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:malonyl-CoA
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Accession:CHEBI:15531 term browser browse the term
Definition:The S-malonyl derivative of coenzyme A.
Synonyms:exact_synonym: 3'-phosphoadenosine 5'-{3-[(3R)-4-{[3-({2-[(3-carboxyacetyl)sulfanyl]ethyl}amino)-3-oxopropyl]amino}-3-hydroxy-2,2-dimethyl-4-oxobutyl] dihydrogen diphosphate}
 related_synonym: Coenzyme A, S-(hydrogen propanedioate);   Formula=C24H38N7O19P3S;   InChI=1S/C24H38N7O19P3S/c1-24(2,19(37)22(38)27-4-3-13(32)26-5-6-54-15(35)7-14(33)34)9-47-53(44,45)50-52(42,43)46-8-12-18(49-51(39,40)41)17(36)23(48-12)31-11-30-16-20(25)28-10-29-21(16)31/h10-12,17-19,23,36-37H,3-9H2,1-2H3,(H,26,32)(H,27,38)(H,33,34)(H,42,43)(H,44,45)(H2,25,28,29)(H2,39,40,41)/t12-,17-,18-,19+,23-/m1/s1;   InChIKey=LTYOQGRJFJAKNA-DVVLENMVSA-N;   Malonyl coenzyme A;   S-(Hydrogen malonyl)coenzyme A;   SMILES=CC(C)(COP(O)(=O)OP(O)(=O)OC[C@H]1O[C@H]([C@H](O)[C@@H]1OP(O)(O)=O)n1cnc2c(N)ncnc12)[C@@H](O)C(=O)NCCC(=O)NCCSC(=O)CC(O)=O
 alt_id: CHEBI:14565;   CHEBI:25135;   CHEBI:43979;   CHEBI:6661
 xref: CAS:524-14-1;   DrugBank:DB04524;   KEGG:C00083;   KNApSAcK:C00007260;   LIPID_MAPS_instance:LMFA07050031
 xref_mesh: MESH:D008316
 xref: MetaCyc:MALONYL-COA;   PDBeChem:MLC;   PMID:11117381;   PMID:11934665;   PMID:16651524;   PMID:17126822;   PMID:17522981;   PMID:18294446;   PMID:21199367;   PMID:21508288;   PMID:21763447;   Reaxys:78309;   Wikipedia:Malonyl-CoA
 cyclic_relationship: is_conjugate_acid_of CHEBI:57384


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malonyl-CoA term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mlycd malonyl-CoA decarboxylase multiple interactions ISO PPARA protein promotes the reaction [MLYCD protein results in decreased abundance of Malonyl Coenzyme A] CTD PMID:14641110 NCBI chr19:52,032,950...52,048,773
Ensembl chr19:52,032,886...52,048,753
JBrowse link
G Ppara peroxisome proliferator activated receptor alpha multiple interactions ISO PPARA protein promotes the reaction [MLYCD protein results in decreased abundance of Malonyl Coenzyme A] CTD PMID:14641110 NCBI chr 7:126,618,872...126,687,282
Ensembl chr 7:126,619,196...126,681,752
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19785
    role 19732
      biological role 19732
        biochemical role 19281
          metabolite 19262
            malonyl-CoA 2
Path 2
Term Annotations click to browse term
  CHEBI ontology 19785
    subatomic particle 19782
      composite particle 19782
        hadron 19782
          baryon 19782
            nucleon 19782
              atomic nucleus 19782
                atom 19782
                  main group element atom 19670
                    p-block element atom 19670
                      chalcogen 19360
                        oxygen atom 19321
                          oxygen molecular entity 19321
                            hydroxides 19066
                              oxoacid 18192
                                pnictogen oxoacid 10144
                                  phosphorus oxoacid 9032
                                    phosphoric acids 7794
                                      phosphoric acid 7794
                                        phosphoric acid derivative 7473
                                          phosphate 7473
                                            organic phosphate 7472
                                              carbohydrate phosphate 1528
                                                phospho sugar 1454
                                                  aldose phosphate 1452
                                                    aldopentose phosphate 1446
                                                      ribose phosphate 1440
                                                        ribonucleotide 1401
                                                          purine ribonucleotide 1374
                                                            adenyl ribonucleotide 1243
                                                              adenosine phosphate 250
                                                                adenosine 5'-phosphate 249
                                                                  ADP 83
                                                                    coenzyme A 28
                                                                      acyl-CoA 28
                                                                        malonyl-CoAs 2
                                                                          malonyl-CoA 2
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