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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:malonyl-CoA
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Accession:CHEBI:15531 term browser browse the term
Definition:The S-malonyl derivative of coenzyme A.
Synonyms:exact_synonym: 3'-phosphoadenosine 5'-{3-[(3R)-4-{[3-({2-[(3-carboxyacetyl)sulfanyl]ethyl}amino)-3-oxopropyl]amino}-3-hydroxy-2,2-dimethyl-4-oxobutyl] dihydrogen diphosphate}
 related_synonym: Coenzyme A, S-(hydrogen propanedioate);   Formula=C24H38N7O19P3S;   InChI=1S/C24H38N7O19P3S/c1-24(2,19(37)22(38)27-4-3-13(32)26-5-6-54-15(35)7-14(33)34)9-47-53(44,45)50-52(42,43)46-8-12-18(49-51(39,40)41)17(36)23(48-12)31-11-30-16-20(25)28-10-29-21(16)31/h10-12,17-19,23,36-37H,3-9H2,1-2H3,(H,26,32)(H,27,38)(H,33,34)(H,42,43)(H,44,45)(H2,25,28,29)(H2,39,40,41)/t12-,17-,18-,19+,23-/m1/s1;   InChIKey=LTYOQGRJFJAKNA-DVVLENMVSA-N;   Malonyl coenzyme A;   S-(Hydrogen malonyl)coenzyme A;   SMILES=CC(C)(COP(O)(=O)OP(O)(=O)OC[C@H]1O[C@H]([C@H](O)[C@@H]1OP(O)(O)=O)n1cnc2c(N)ncnc12)[C@@H](O)C(=O)NCCC(=O)NCCSC(=O)CC(O)=O
 alt_id: CHEBI:14565;   CHEBI:25135;   CHEBI:43979;   CHEBI:6661
 xref: CAS:524-14-1;   DrugBank:DB04524;   KEGG:C00083;   KNApSAcK:C00007260;   LIPID_MAPS_instance:LMFA07050031
 xref_mesh: MESH:D008316
 xref: MetaCyc:MALONYL-COA;   PDBeChem:MLC;   PMID:11117381;   PMID:11934665;   PMID:16651524;   PMID:17126822;   PMID:17522981;   PMID:18294446;   PMID:21199367;   PMID:21508288;   PMID:21763447;   Reaxys:78309;   Wikipedia:Malonyl-CoA
 cyclic_relationship: is_conjugate_acid_of CHEBI:57384


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malonyl-CoA term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mlycd malonyl-CoA decarboxylase multiple interactions ISO PPARA protein promotes the reaction [MLYCD protein results in decreased abundance of Malonyl Coenzyme A] CTD PMID:14641110 NCBI chr19:47,447,931...47,463,794
Ensembl chr19:47,447,970...47,463,793
JBrowse link
G Ppara peroxisome proliferator activated receptor alpha multiple interactions ISO PPARA protein promotes the reaction [MLYCD protein results in decreased abundance of Malonyl Coenzyme A] CTD PMID:14641110 NCBI chr 7:116,832,405...116,900,878
Ensembl chr 7:116,832,756...116,895,346
JBrowse link

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Path 1
Term Annotations click to browse term
  CHEBI ontology 19812
    role 19761
      biological role 19761
        biochemical role 19381
          metabolite 19356
            malonyl-CoA 2
Path 2
Term Annotations click to browse term
  CHEBI ontology 19812
    subatomic particle 19811
      composite particle 19811
        hadron 19811
          baryon 19811
            nucleon 19811
              atomic nucleus 19811
                atom 19811
                  main group element atom 19708
                    p-block element atom 19708
                      chalcogen 19460
                        oxygen atom 19436
                          oxygen molecular entity 19436
                            hydroxides 19175
                              oxoacid 18488
                                pnictogen oxoacid 10688
                                  phosphorus oxoacid 9669
                                    phosphoric acids 8466
                                      phosphoric acid 8466
                                        phosphoric acid derivative 8171
                                          phosphate 8170
                                            organic phosphate 8169
                                              carbohydrate phosphate 1734
                                                phospho sugar 1659
                                                  aldose phosphate 1657
                                                    aldopentose phosphate 1651
                                                      ribose phosphate 1646
                                                        ribonucleotide 1607
                                                          purine ribonucleotide 1580
                                                            adenyl ribonucleotide 1283
                                                              adenosine phosphate 274
                                                                adenosine 5'-phosphate 273
                                                                  ADP 87
                                                                    coenzyme A 28
                                                                      acyl-CoA 28
                                                                        malonyl-CoAs 2
                                                                          malonyl-CoA 2
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