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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:lauroyl-CoA
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Accession:CHEBI:15521 term browser browse the term
Definition:A medium-chain fatty acyl-CoA that results from the formal condensation of the thiol group of coenzyme A with the carboxy group of lauric (dodecanoic) acid.
Synonyms:exact_synonym: 3'-phosphoadenosine 5'-(3-{(3R)-4-[(3-{[2-(dodecanoylsulfanyl)ethyl]amino}-3-oxopropyl)amino]-3-hydroxy-2,2-dimethyl-4-oxobutyl} dihydrogen diphosphate)
 related_synonym: C12:0-CoA;   Dodecanoyl-CoA;   Formula=C33H58N7O17P3S;   InChI=1S/C33H58N7O17P3S/c1-4-5-6-7-8-9-10-11-12-13-24(42)61-17-16-35-23(41)14-15-36-31(45)28(44)33(2,3)19-54-60(51,52)57-59(49,50)53-18-22-27(56-58(46,47)48)26(43)32(55-22)40-21-39-25-29(34)37-20-38-30(25)40/h20-22,26-28,32,43-44H,4-19H2,1-3H3,(H,35,41)(H,36,45)(H,49,50)(H,51,52)(H2,34,37,38)(H2,46,47,48)/t22-,26-,27-,28+,32-/m1/s1;   InChIKey=YMCXGHLSVALICC-GMHMEAMDSA-N;   Lauroyl-coenzyme A;   SMILES=CCCCCCCCCCCC(=O)SCCNC(=O)CCNC(=O)[C@H](O)C(C)(C)COP(O)(=O)OP(O)(=O)OC[C@H]1O[C@H]([C@H](O)[C@@H]1OP(O)(O)=O)N1C=NC2=C1N=CN=C2N;   coenzyme A, S-dodecanoate;   dodecanoyl-coenzyme A
 alt_id: CHEBI:14188;   CHEBI:14501;   CHEBI:25014;   CHEBI:41874;   CHEBI:6392
 xref: CAS:6244-92-4;   Chemspider:145018;   DrugBank:DB03264;   FooDB:FDB023198;   HMDB:HMDB0003571;   KEGG:C01832;   LIPID_MAPS_instance:LMFA07050340
 xref_mesh: MESH:C050466
 xref: PDBeChem:DCC;   PMID:10652339;   PMID:1263766;   PMID:15713483;   PMID:15849423;   PMID:16021622;   PMID:16665518;   PMID:21349973;   PMID:22906002;   PMID:24356978;   PMID:27815501;   PMID:30948713;   PMID:31935250;   PMID:33885999;   PMID:3778940;   PMID:627552;   PMID:7551821;   Reaxys:8033507;   UM-BBD_compID:c0567
 cyclic_relationship: is_conjugate_acid_of CHEBI:57375



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lauroyl-CoA term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gsta1 glutathione S-transferase alpha 1 multiple interactions ISO lauroyl-coenzyme A binds to and results in decreased activity of GSTA1 protein CTD PMID:10542059 NCBI chr 9:23,703,476...23,720,121
Ensembl chr 9:23,703,477...23,720,121
JBrowse link
G Hsdl2 hydroxysteroid dehydrogenase like 2 multiple interactions ISO [lauroyl-coenzyme A co-treated with NADP] binds to HSDL2 protein CTD PMID:25526675 NCBI chr 5:74,443,933...74,479,104
Ensembl chr 5:74,443,872...74,479,839
JBrowse link
G Pecr peroxisomal trans-2-enoyl-CoA reductase multiple interactions ISO [lauroyl-coenzyme A co-treated with NADP] binds to PECR protein CTD PMID:25526675 NCBI chr 9:73,897,877...73,926,511
Ensembl chr 9:73,897,880...73,926,511
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19810
    role 19759
      biological role 19759
        antimicrobial agent 17402
          antibacterial agent 13570
            dodecanoic acid 172
              lauroyl-CoA 3
                (S)-3-hydroxylauroyl-CoA 0
                3-oxolauroyl-CoA 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19810
    subatomic particle 19809
      composite particle 19809
        hadron 19809
          baryon 19809
            nucleon 19809
              atomic nucleus 19809
                atom 19809
                  main group element atom 19706
                    p-block element atom 19706
                      chalcogen 19458
                        oxygen atom 19434
                          oxygen molecular entity 19434
                            hydroxides 19171
                              oxoacid 18489
                                pnictogen oxoacid 10690
                                  phosphorus oxoacid 9671
                                    phosphoric acids 8468
                                      phosphoric acid 8468
                                        phosphoric acid derivative 8173
                                          phosphate 8173
                                            organic phosphate 8172
                                              carbohydrate phosphate 1735
                                                phospho sugar 1660
                                                  aldose phosphate 1658
                                                    aldopentose phosphate 1652
                                                      ribose phosphate 1647
                                                        ribonucleotide 1608
                                                          purine ribonucleotide 1581
                                                            adenyl ribonucleotide 1283
                                                              adenosine phosphate 274
                                                                adenosine 5'-phosphate 273
                                                                  ADP 87
                                                                    coenzyme A 28
                                                                      acyl-CoA 28
                                                                        fatty acyl-CoA 16
                                                                          medium-chain fatty acyl-CoA 3
                                                                            lauroyl-CoA 3
                                                                              (S)-3-hydroxylauroyl-CoA 0
                                                                              3-oxolauroyl-CoA 0
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