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The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at The data is made available under the Creative Commons License (CC BY 3.0, For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

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Accession:CHEBI:15521 term browser browse the term
Definition:A medium-chain fatty acyl-CoA that results from the formal condensation of the thiol group of coenzyme A with the carboxy group of lauric (dodecanoic) acid.
Synonyms:exact_synonym: 3'-phosphoadenosine 5'-(3-{(3R)-4-[(3-{[2-(dodecanoylsulfanyl)ethyl]amino}-3-oxopropyl)amino]-3-hydroxy-2,2-dimethyl-4-oxobutyl} dihydrogen diphosphate)
 related_synonym: C12:0-CoA;   Dodecanoyl-CoA;   Formula=C33H58N7O17P3S;   InChI=1S/C33H58N7O17P3S/c1-4-5-6-7-8-9-10-11-12-13-24(42)61-17-16-35-23(41)14-15-36-31(45)28(44)33(2,3)19-54-60(51,52)57-59(49,50)53-18-22-27(56-58(46,47)48)26(43)32(55-22)40-21-39-25-29(34)37-20-38-30(25)40/h20-22,26-28,32,43-44H,4-19H2,1-3H3,(H,35,41)(H,36,45)(H,49,50)(H,51,52)(H2,34,37,38)(H2,46,47,48)/t22-,26-,27-,28+,32-/m1/s1;   InChIKey=YMCXGHLSVALICC-GMHMEAMDSA-N;   Lauroyl-coenzyme A;   SMILES=CCCCCCCCCCCC(=O)SCCNC(=O)CCNC(=O)[C@H](O)C(C)(C)COP(O)(=O)OP(O)(=O)OC[C@H]1O[C@H]([C@H](O)[C@@H]1OP(O)(O)=O)N1C=NC2=C1N=CN=C2N;   coenzyme A, S-dodecanoate;   dodecanoyl-coenzyme A
 alt_id: CHEBI:14188;   CHEBI:14501;   CHEBI:25014;   CHEBI:41874;   CHEBI:6392
 xref: CAS:6244-92-4;   Chemspider:145018;   DrugBank:DB03264;   FooDB:FDB023198;   HMDB:HMDB0003571;   KEGG:C01832;   LIPID_MAPS_instance:LMFA07050340
 xref_mesh: MESH:C050466
 xref: PDBeChem:DCC;   PMID:10652339;   PMID:1263766;   PMID:15713483;   PMID:15849423;   PMID:16021622;   PMID:16665518;   PMID:21349973;   PMID:22906002;   PMID:24356978;   PMID:27815501;   PMID:30948713;   PMID:31935250;   PMID:33885999;   PMID:3778940;   PMID:627552;   PMID:7551821;   Reaxys:8033507;   UM-BBD_compID:c0567
 cyclic_relationship: is_conjugate_acid_of CHEBI:57375

show annotations for term's descendants           Sort by:
lauroyl-CoA term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gsta1 glutathione S-transferase alpha 1 multiple interactions ISO lauroyl-coenzyme A binds to and results in decreased activity of GSTA1 protein CTD PMID:10542059 NCBI chr 9:23,703,476...23,720,121
Ensembl chr 9:23,703,477...23,720,121
JBrowse link
G Hsdl2 hydroxysteroid dehydrogenase like 2 multiple interactions ISO [lauroyl-coenzyme A co-treated with NADP] binds to HSDL2 protein CTD PMID:25526675 NCBI chr 5:74,443,933...74,479,104
Ensembl chr 5:74,443,872...74,479,839
JBrowse link
G Pecr peroxisomal trans-2-enoyl-CoA reductase multiple interactions ISO [lauroyl-coenzyme A co-treated with NADP] binds to PECR protein CTD PMID:25526675 NCBI chr 9:73,897,877...73,926,511
Ensembl chr 9:73,897,880...73,926,511
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 20056
    role 20008
      biological role 20007
        antimicrobial agent 17793
          antibacterial agent 14305
            dodecanoic acid 188
              lauroyl-CoA 3
                (S)-3-hydroxylauroyl-CoA 0
                3-oxolauroyl-CoA 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 20056
    subatomic particle 20054
      composite particle 20054
        hadron 20054
          baryon 20054
            nucleon 20054
              atomic nucleus 20054
                atom 20054
                  main group element atom 19956
                    p-block element atom 19956
                      chalcogen 19693
                        oxygen atom 19666
                          oxygen molecular entity 19666
                            hydroxides 19412
                              oxoacid 18715
                                pnictogen oxoacid 11007
                                  phosphorus oxoacid 9812
                                    phosphoric acids 8640
                                      phosphoric acid 8640
                                        phosphoric acid derivative 8344
                                          phosphate 8344
                                            organic phosphate 8343
                                              carbohydrate phosphate 1831
                                                phospho sugar 1679
                                                  aldose phosphate 1677
                                                    aldopentose phosphate 1669
                                                      ribose phosphate 1664
                                                        ribonucleotide 1623
                                                          purine ribonucleotide 1596
                                                            adenyl ribonucleotide 1299
                                                              adenosine phosphate 289
                                                                adenosine 5'-phosphate 288
                                                                  ADP 87
                                                                    coenzyme A 28
                                                                      acyl-CoA 28
                                                                        fatty acyl-CoA 16
                                                                          medium-chain fatty acyl-CoA 3
                                                                            lauroyl-CoA 3
                                                                              (S)-3-hydroxylauroyl-CoA 0
                                                                              3-oxolauroyl-CoA 0
paths to the root