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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:3-hydroxykynurenine
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Accession:CHEBI:1547 term browser browse the term
Definition:A hydroxykynurenine that is kynurenine substituted by a hydroxy group at position 3.
Synonyms:exact_synonym: 3-(2-amino-3-hydroxybenzoyl)alanine
 related_synonym: 2-amino-4-(2-amino-3-hydroxyphenyl)-4-oxobutanoic acid;   3-(3-hydroxyanthraniloyl)alanine;   3-Hydroxy-DL-kynurenine;   Formula=C10H12N2O4;   InChI=1S/C10H12N2O4/c11-6(10(15)16)4-8(14)5-2-1-3-7(13)9(5)12/h1-3,6,13H,4,11-12H2,(H,15,16);   InChIKey=VCKPUUFAIGNJHC-UHFFFAOYSA-N;   SMILES=NC(CC(=O)c1cccc(O)c1N)C(O)=O
 xref: CAS:484-78-6;   HMDB:HMDB0000732;   KEGG:C02794
 xref_mesh: MESH:C005045
 xref: PMID:11477208;   PMID:15206726;   Reaxys:2697635


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3-hydroxykynurenine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Kmo kynurenine 3-monooxygenase multiple interactions EXP [KMO protein results in increased hydroxylation of Kynurenine] which results in increased chemical synthesis of 3-hydroxykynurenine CTD PMID:32243540 NCBI chr13:87,557,080...87,589,334
Ensembl chr13:87,557,286...87,588,881
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Term Annotations click to browse term
  CHEBI ontology 19808
    role 19757
      biological role 19757
        biochemical role 19377
          metabolite 19352
            eukaryotic metabolite 19040
              animal metabolite 18883
                mammalian metabolite 18882
                  human metabolite 18344
                    3-hydroxykynurenine 1
                      3-hydroxy-L-kynurenine 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19808
    subatomic particle 19807
      composite particle 19807
        hadron 19807
          baryon 19807
            nucleon 19807
              atomic nucleus 19807
                atom 19807
                  main group element atom 19704
                    p-block element atom 19704
                      carbon group element atom 19626
                        carbon atom 19616
                          organic molecular entity 19616
                            organic group 18725
                              organic divalent group 18716
                                organodiyl group 18716
                                  carbonyl group 18664
                                    carbonyl compound 18664
                                      carboxylic acid 18361
                                        amino acid 14876
                                          alpha-amino acid 12852
                                            non-proteinogenic alpha-amino acid 1740
                                              hydroxy-amino acid 3
                                                hydroxykynurenine 1
                                                  3-hydroxykynurenine 1
                                                    3-hydroxy-L-kynurenine 0
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