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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:ATP
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Accession:CHEBI:15422 term browser browse the term
Definition:An adenosine 5'-phosphate in which the 5'-phosphate is a triphosphate group. It is involved in the transportation of chemical energy during metabolic pathways.
Synonyms:related_synonym: ADENOSINE-5'-TRIPHOSPHATE;   Adenosine triphosphate;   Formula=C10H16N5O13P3;   H4atp;   InChI=1S/C10H16N5O13P3/c11-8-5-9(13-2-12-8)15(3-14-5)10-7(17)6(16)4(26-10)1-25-30(21,22)28-31(23,24)27-29(18,19)20/h2-4,6-7,10,16-17H,1H2,(H,21,22)(H,23,24)(H2,11,12,13)(H2,18,19,20)/t4-,6-,7-,10-/m1/s1;   InChIKey=ZKHQWZAMYRWXGA-KQYNXXCUSA-N;   SMILES=Nc1ncnc2n(cnc12)[C@@H]1O[C@H](COP(O)(=O)OP(O)(=O)OP(O)(O)=O)[C@@H](O)[C@H]1O;   adenosine 5'-(tetrahydrogen triphosphate)
 alt_id: CHEBI:10789;   CHEBI:10841;   CHEBI:13236;   CHEBI:22249;   CHEBI:2359;   CHEBI:40938
 xref: Beilstein:73010;   CAS:56-65-5;   DrugBank:DB00171;   Drug_Central:91;   Gmelin:34857;   HMDB:HMDB0000538;   KEGG:C00002;   KEGG:D08646;   KNApSAcK:C00001491
 xref_mesh: MESH:D000255
 xref: PDBeChem:ATP;   Patent:US3079379;   Reaxys:73010;   Wikipedia:Adenosine_triphosphate
 cyclic_relationship: is_conjugate_acid_of CHEBI:57299


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ATP term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BCL2 BCL2 apoptosis regulator multiple interactions
increases expression
EXP tetrakis(N-methyl-4-pyridiniumyl)porphine manganese(III) complex inhibits the reaction [Adenosine Triphosphate results in increased expression of BCL2 protein] CTD PMID:17997382 NCBI chr 1:158,337,403...158,518,214
Ensembl chr 1:158,288,544...158,518,879
JBrowse link
G CASP8 caspase 8 increases activity
multiple interactions
EXP Adenosine Triphosphate results in increased activity of CASP8 protein
tetrakis(N-methyl-4-pyridiniumyl)porphine manganese(III) complex inhibits the reaction [Adenosine Triphosphate results in increased activity of CASP8 protein]
CTD PMID:17997382 NCBI chr15:104,923,659...104,948,470
Ensembl chr15:104,923,953...104,948,470
JBrowse link
G CYCS cytochrome c, somatic affects localization
multiple interactions
EXP Adenosine Triphosphate affects the localization of CYCS protein
[Calcium co-treated with Phosphates co-treated with Adenosine Triphosphate] affects the localization of CYCS protein; tetrakis(N-methyl-4-pyridiniumyl)porphine manganese(III) complex inhibits the reaction [Adenosine Triphosphate affects the localization of CYCS protein]
CTD PMID:16489745 PMID:17997382 NCBI chr18:47,169,921...47,172,212
Ensembl chr18:47,169,866...47,173,866
JBrowse link
G MYL9 myosin light chain 9 decreases phosphorylation
multiple interactions
EXP Adenosine Triphosphate results in decreased phosphorylation of MYL9 protein
1,2-bis(2-aminophenoxy)ethane-N,N,N',N'-tetraacetic acid inhibits the reaction [Adenosine Triphosphate promotes the reaction [calyculin A results in increased phosphorylation of MYL9 protein]]; Adenosine Triphosphate promotes the reaction [calyculin A results in increased phosphorylation of MYL9 protein]
CTD PMID:10942722 NCBI chr17:39,788,165...39,795,240
Ensembl chr17:39,788,199...39,795,296
JBrowse link
G TNF tumor necrosis factor increases expression
multiple interactions
EXP Adenosine Triphosphate results in increased expression of TNF protein
tetrakis(N-methyl-4-pyridiniumyl)porphine manganese(III) complex inhibits the reaction [Adenosine Triphosphate results in increased expression of TNF protein]
CTD PMID:17997382 NCBI chr 7:23,699,635...23,702,393
Ensembl chr 7:23,699,636...23,703,655
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 875
    role 855
      biological role 855
        biochemical role 726
          cofactor 131
            ATP 5
              2-hydroxy-ATP 0
              3'-dehydro-ATP 0
              9-ribosyl-trans-zeatin 5'-triphosphate 0
              ATP-sugar + 0
              N(6)-(dimethylallyl)adenosine 5'-triphosphate 0
              TNP-ATP 0
              adenosine 5'-[gamma-thio]triphosphate 0
              adenosine thiamine triphosphate 0
              adenosine triphosphate disodium 0
              ethyl-ATP 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 875
    subatomic particle 860
      composite particle 860
        hadron 860
          baryon 860
            nucleon 860
              atomic nucleus 860
                atom 860
                  main group element atom 850
                    p-block element atom 847
                      chalcogen 809
                        oxygen atom 756
                          oxygen molecular entity 756
                            hydroxides 681
                              oxoacid 311
                                pnictogen oxoacid 59
                                  phosphorus oxoacid 57
                                    phosphoric acids 48
                                      phosphoric acid 48
                                        phosphoric acid derivative 48
                                          phosphate 48
                                            organic phosphate 48
                                              carbohydrate phosphate 26
                                                phospho sugar 14
                                                  aldose phosphate 14
                                                    aldopentose phosphate 14
                                                      ribose phosphate 14
                                                        ribonucleotide 14
                                                          purine ribonucleotide 14
                                                            adenyl ribonucleotide 11
                                                              adenosine phosphate 5
                                                                adenosine 5'-phosphate 5
                                                                  ATP 5
                                                                    2-hydroxy-ATP 0
                                                                    3'-dehydro-ATP 0
                                                                    9-ribosyl-trans-zeatin 5'-triphosphate 0
                                                                    ATP-sugar + 0
                                                                    N(6)-(dimethylallyl)adenosine 5'-triphosphate 0
                                                                    TNP-ATP 0
                                                                    adenosine 5'-[gamma-thio]triphosphate 0
                                                                    adenosine thiamine triphosphate 0
                                                                    adenosine triphosphate disodium 0
                                                                    ethyl-ATP 0
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