CHEBI ONTOLOGY - ANNOTATIONS
The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/ . The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/ ). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term: 2',4,4',6'-tetrahydroxychalcone
Accession: CHEBI:15413
browse the term
Definition: A member of the class of chalcones that is trans-chalcone substituted by hydroxy groups at positions 2' ,4, 4', and 6' respectively.
Synonyms: exact_synonym: (2E)-3-(4-hydroxyphenyl)-1-(2,4,6-trihydroxyphenyl)prop-2-en-1-one
related_synonym: Chalconaringenin; Formula=C15H12O5; InChI=1S/C15H12O5/c16-10-4-1-9(2-5-10)3-6-12(18)15-13(19)7-11(17)8-14(15)20/h1-8,16-17,19-20H/b6-3+; InChIKey=YQHMWTPYORBCMF-ZZXKWVIFSA-N; Isosalipurpol; Naringenin chalcone; SMILES=Oc1ccc(cc1)\\C=C\\C(=O)c1c(O)cc(O)cc1O
alt_id: CHEBI:10785; CHEBI:14641; CHEBI:19219; CHEBI:6055
xref: CAS:73692-50-9; KEGG:C06561; KNApSAcK:C00007233; LIPID_MAPS_instance:LMPK12120264
xref_mesh: MESH:C027329
xref: PMID:15322354; PMID:17915259; PMID:20035147; PMID:20363289; PMID:20815398; Reaxys:2335724
G
Ugt1a1
UDP glucuronosyltransferase family 1 member A1
increases glucuronidation
ISO
UGT1A1 protein results in increased glucuronidation of naringenin chalcone
CTD
PMID:14557274
NCBI chr 9:88,801,344...88,808,465
Ensembl chr 9:88,713,184...88,808,465
G
Ugt1a9
UDP glucuronosyltransferase family 1 member A9
increases glucuronidation
ISO
UGT1A9 protein results in increased glucuronidation of naringenin chalcone
CTD
PMID:14557274
NCBI chr 9:88,696,981...88,808,465
Ensembl chr 9:88,713,184...88,808,465
Term paths to the root one shortest all shortest one longest all longest one shortest and longest all
Path 1
CHEBI ontology
19812
role
19784
application
19615
anti-inflammatory agent
16506
2',4,4',6'-tetrahydroxychalcone
2
2',4,4',6'-tetrahydroxychalcone 4'-O-beta-D-glucoside
0
2',4,4',6'-tetrahydroxychalcone(1-)
0
Path 2
CHEBI ontology
19812
subatomic particle
19810
composite particle
19810
hadron
19810
baryon
19810
nucleon
19810
atomic nucleus
19810
atom
19810
main group element atom
19755
p-block element atom
19755
carbon group element atom
19698
carbon atom
19693
organic molecular entity
19693
organic group
18902
organic divalent group
18884
organodiyl group
18884
carbonyl group
18850
carbonyl compound
18850
ketone
17140
alpha,beta-unsaturated ketone
9970
enone
9970
chalcones
926
chalcone
106
trans-chalcone
106
2',4,4',6'-tetrahydroxychalcone
2
2',4,4',6'-tetrahydroxychalcone 4'-O-beta-D-glucoside
0
2',4,4',6'-tetrahydroxychalcone(1-)
0