CHEBI ONTOLOGY - ANNOTATIONS
The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/ . The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/ ). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term: 2',4,4',6'-tetrahydroxychalcone
Accession: CHEBI:15413
browse the term
Definition: A member of the class of chalcones that is trans-chalcone substituted by hydroxy groups at positions 2' ,4, 4', and 6' respectively.
Synonyms: exact_synonym: (2E)-3-(4-hydroxyphenyl)-1-(2,4,6-trihydroxyphenyl)prop-2-en-1-one
related_synonym: Chalconaringenin; Formula=C15H12O5; InChI=1S/C15H12O5/c16-10-4-1-9(2-5-10)3-6-12(18)15-13(19)7-11(17)8-14(15)20/h1-8,16-17,19-20H/b6-3+; InChIKey=YQHMWTPYORBCMF-ZZXKWVIFSA-N; Isosalipurpol; Naringenin chalcone; SMILES=Oc1ccc(cc1)\\C=C\\C(=O)c1c(O)cc(O)cc1O
alt_id: CHEBI:10785; CHEBI:14641; CHEBI:19219; CHEBI:6055
xref: CAS:73692-50-9; KEGG:C06561; KNApSAcK:C00007233; LIPID_MAPS_instance:LMPK12120264
xref_mesh: MESH:C027329
xref: PMID:15322354; PMID:17915259; PMID:20035147; PMID:20363289; PMID:20815398; Reaxys:2335724
G
Ugt1a1
UDP glucuronosyltransferase family 1 member A1
increases glucuronidation
ISO
UGT1A1 protein results in increased glucuronidation of naringenin chalcone
CTD
PMID:14557274
NCBI chr 9:88,801,344...88,808,465
Ensembl chr 9:88,713,184...88,808,465
G
Ugt1a9
UDP glucuronosyltransferase family 1 member A9
increases glucuronidation
ISO
UGT1A9 protein results in increased glucuronidation of naringenin chalcone
CTD
PMID:14557274
NCBI chr 9:88,696,981...88,808,465
Ensembl chr 9:88,713,184...88,808,465
Term paths to the root one shortest all shortest one longest all longest one shortest and longest all
Path 1
CHEBI ontology
20845
role
20805
application
20606
anti-inflammatory agent
16814
2',4,4',6'-tetrahydroxychalcone
2
2',4,4',6'-tetrahydroxychalcone 4'-O-beta-D-glucoside
0
2',4,4',6'-tetrahydroxychalcone(1-)
0
Path 2
CHEBI ontology
20845
subatomic particle
20843
composite particle
20843
hadron
20843
baryon
20843
nucleon
20843
atomic nucleus
20843
atom
20843
main group element atom
20766
p-block element atom
20766
carbon group element atom
20699
carbon atom
20693
organic molecular entity
20693
heteroorganic entity
20202
organochalcogen compound
19890
organooxygen compound
19792
carbonyl compound
19423
ketone
17441
alpha,beta-unsaturated ketone
10053
enone
10053
chalcones
947
chalcone
133
trans-chalcone
133
2',4,4',6'-tetrahydroxychalcone
2
2',4,4',6'-tetrahydroxychalcone 4'-O-beta-D-glucoside
0
2',4,4',6'-tetrahydroxychalcone(1-)
0