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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:(-)-ephedrine
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Accession:CHEBI:15407 term browser browse the term
Definition:A phenethylamine alkaloid that is 2-phenylethanamine substituted by a methyl group at the amino nitrogen and a methyl and a hydroxy group at position 2 and 1 respectively.
Synonyms:exact_synonym: (1R,2S)-2-(methylamino)-1-phenylpropan-1-ol
 related_synonym: (1R,2S)-1-phenyl-1-hydroxy-2-methylaminopropane;   Formula=C10H15NO;   InChI=1S/C10H15NO/c1-8(11-2)10(12)9-6-4-3-5-7-9/h3-8,10-12H,1-2H3/t8-,10-/m0/s1;   InChIKey=KWGRBVOPPLSCSI-WPRPVWTQSA-N;   L-Ephedrine;   L-erythro-2-(methylamino)-1-phenylpropan-1-ol;   SMILES=CN[C@@H](C)[C@H](O)c1ccccc1
 alt_id: CHEBI:10776;   CHEBI:132176;   CHEBI:18483;   CHEBI:4801
 xref: CAS:299-42-3;   Chemspider:4856;   DrugBank:DB01364;   Drug_Central:1024;   Gmelin:261389;   KEGG:C01575;   KEGG:D00124;   KNApSAcK:C00001409
 xref_mesh: MESH:D004809
 xref: PMID:13359219;   PMID:13809594;   PMID:21465337;   PMID:25660335;   PMID:27662264;   PMID:27846433;   Reaxys:2208730;   VSDB:2959;   Wikipedia:Ephedrine
 cyclic_relationship: is_conjugate_base_of CHEBI:57295


show annotations for term's descendants           Sort by:
(-)-ephedrine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Apoa1 apolipoprotein A1 multiple interactions ISO [Ephedrine co-treated with Caffeine] results in increased expression of APOA1 protein CTD PMID:16324916 NCBI chr 8:46,527,251...46,529,035
Ensembl chr 8:46,527,144...46,529,035 		JBrowse link
G Apoa2 apolipoprotein A2 multiple interactions ISO [Ephedrine co-treated with Caffeine] results in decreased expression of APOA2 protein CTD PMID:16324916 NCBI chr13:83,644,460...83,646,358
Ensembl chr13:83,644,470...83,646,355 		JBrowse link
G Apob apolipoprotein B multiple interactions ISO [Ephedrine co-treated with Caffeine] results in decreased expression of APOB protein CTD PMID:16324916 NCBI chr 6:30,844,386...30,883,983
Ensembl chr 6:30,844,368...30,892,497 		JBrowse link
G Apoc1 apolipoprotein C1 multiple interactions ISO [Ephedrine co-treated with Caffeine co-treated with pioglitazone] results in increased expression of APOC1 protein CTD PMID:16324916 NCBI chr 1:79,347,057...79,350,340
Ensembl chr 1:79,346,136...79,350,375 		JBrowse link
G Apoc2 apolipoprotein C2 multiple interactions ISO [Ephedrine co-treated with Caffeine co-treated with pioglitazone] results in decreased expression of APOC2 protein CTD PMID:16324916 NCBI chr 1:79,329,429...79,334,397
Ensembl chr 1:79,329,428...79,334,476 		JBrowse link
G Apoc3 apolipoprotein C3 multiple interactions ISO [Ephedrine co-treated with Caffeine co-treated with pioglitazone] results in decreased expression of APOC3 protein CTD PMID:16324916 NCBI chr 8:46,531,478...46,533,658
Ensembl chr 8:46,531,478...46,533,583 		JBrowse link
G Casp3 caspase 3 multiple interactions EXP [Caffeine co-treated with Ephedrine] results in increased cleavage of CASP3 protein CTD PMID:15537744 NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648 		JBrowse link
G Cfd complement factor D multiple interactions ISO [Caffeine co-treated with Ephedrine] affects the reaction [Sodium Glutamate results in decreased expression of CFD mRNA]; [Caffeine co-treated with Ephedrine] affects the reaction [Sodium Glutamate results in decreased expression of CFD protein] CTD PMID:2307116 NCBI chr 7:9,813,148...9,814,871
Ensembl chr 7:9,813,150...9,815,053 		JBrowse link
G Fos Fos proto-oncogene, AP-1 transcription factor subunit increases expression ISO Ephedrine results in increased expression of FOS mRNA CTD PMID:12730611 NCBI chr 6:105,121,170...105,124,036
Ensembl chr 6:105,121,170...105,124,036 		JBrowse link
G H2ax H2A.X variant histone multiple interactions EXP [Caffeine co-treated with Ephedrine] results in increased phosphorylation of H2AX protein CTD PMID:15537744 NCBI chr 8:44,671,907...44,673,262
Ensembl chr 8:44,671,786...44,673,239 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19900
    role 19875
      biological role 19873
        xenobiotic 18765
          (-)-ephedrine 10
Path 2
Term Annotations click to browse term
  CHEBI ontology 19900
    subatomic particle 19898
      composite particle 19898
        hadron 19898
          baryon 19898
            nucleon 19898
              atomic nucleus 19898
                atom 19898
                  main group element atom 19845
                    main group molecular entity 19845
                      s-block molecular entity 19678
                        hydrogen molecular entity 19667
                          hydrides 19146
                            inorganic hydride 18124
                              pnictogen hydride 18112
                                nitrogen hydride 18017
                                  azane 17816
                                    ammonia 17815
                                      organic amino compound 17815
                                        amino alcohol 1067
                                          ethanolamines 819
                                            phenylethanolamines 597
                                              (-)-ephedrine 10
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