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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:water
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Accession:CHEBI:15377 term browser browse the term
Definition:An oxygen hydride consisting of an oxygen atom that is covalently bonded to two hydrogen atoms.
Synonyms:exact_synonym: oxidane
 related_synonym: BOUND WATER;   Formula=H2O;   H2O;   HOH;   InChI=1S/H2O/h1H2;   InChIKey=XLYOFNOQVPJJNP-UHFFFAOYSA-N;   SMILES=[H]O[H];   Wasser;   [OH2];   acqua;   agua;   aqua;   dihydridooxygen;   dihydrogen oxide;   eau;   hydrogen hydroxide
 alt_id: CHEBI:10743;   CHEBI:13352;   CHEBI:27313;   CHEBI:42043;   CHEBI:42857;   CHEBI:43228;   CHEBI:44292;   CHEBI:44701;   CHEBI:44819;   CHEBI:5585
 xref: Beilstein:3587155;   CAS:7732-18-5;   Gmelin:117;   HMDB:HMDB0002111;   KEGG:C00001;   KEGG:D00001
 xref_mesh: MESH:D014867
 xref: MetaCyc:WATER;   MolBase:1;   PDBeChem:HOH;   Reaxys:3587155;   Wikipedia:Water
 cyclic_relationship: is_conjugate_acid_of CHEBI:16234;   is_conjugate_base_of CHEBI:29412


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water term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Akt1 AKT serine/threonine kinase 1 multiple interactions ISO [[Particulate Matter co-treated with Water] results in increased abundance of Metals] which results in increased expression of AKT1 mRNA CTD PMID:29335169 NCBI chr 6:137,218,398...137,239,970
Ensembl chr 6:137,218,376...137,236,258
JBrowse link
G Aqp1 aquaporin 1 increases transport
multiple interactions
ISO
EXP
AQP1 protein results in increased transport of Water
Mercuric Chloride inhibits the reaction [AQP1 protein results in increased transport of Water]; Mercury inhibits the reaction [AQP1 protein results in increased transport of Water]
CTD PMID:7528928, PMID:8457558, PMID:10559675, PMID:11035042, PMID:11078688, PMID:21251984, PMID:21259319 NCBI chr 4:85,551,503...85,563,683
Ensembl chr 4:85,551,502...85,569,360
JBrowse link
G Aqp11 aquaporin 11 multiple interactions
increases transport
ISO Mercaptoethanol inhibits the reaction [Mercuric Chloride inhibits the reaction [AQP11 protein results in increased transport of Water]]; Mercuric Chloride inhibits the reaction [AQP11 protein results in increased transport of Water] CTD PMID:21251984 NCBI chr 1:162,703,394...162,713,560
Ensembl chr 1:162,703,442...162,713,610
JBrowse link
G Aqp2 aquaporin 2 increases expression EXP Water deficiency results in increased expression of AQP2 mRNA CTD PMID:15462210 NCBI chr 7:141,237,802...141,242,837
Ensembl chr 7:141,237,768...141,245,165
JBrowse link
G Aqp3 aquaporin 3 (Gill blood group) multiple interactions
increases expression
increases transport
ISO
EXP
Dexamethasone promotes the reaction [AQP3 protein results in increased transport of Water]; Mercaptoethanol inhibits the reaction [Mercuric Chloride inhibits the reaction [AQP3 protein results in increased transport of Water]]; Mercuric Chloride inhibits the reaction [AQP3 protein results in increased transport of Water]; Mercuric Chloride inhibits the reaction [Dexamethasone promotes the reaction [AQP3 protein results in increased transport of Water]]
Water deficiency results in increased expression of AQP3 mRNA; Water deficiency results in increased expression of AQP3 protein
Copper Sulfate inhibits the reaction [AQP3 protein results in increased transport of Water]; Mercuric Chloride inhibits the reaction [AQP3 protein results in increased transport of Water]
CTD PMID:9124401, PMID:9374739, PMID:15462210, PMID:22687538 NCBI chr 5:57,423,735...57,429,252
Ensembl chr 5:57,423,734...57,429,245
JBrowse link
G Aqp4 aquaporin 4 increases transport
increases response to substance
increases expression
affects transport
EXP
ISO
AQP4 protein results in increased transport of Water
AQP4 protein results in increased susceptibility to Water
Water deficiency results in increased expression of AQP4 mRNA
AQP4 protein affects the transport of Water
CTD PMID:7528931, PMID:15462210, PMID:20815926, PMID:21251984 NCBI chr18:6,766,009...6,782,757
Ensembl chr18:6,765,945...6,782,996
JBrowse link
G Aqp7 aquaporin 7 affects transport
increases transport
EXP AQP7 protein affects the transport of Water
AQP7 protein results in increased transport of Water
CTD PMID:9252401, PMID:18059526 NCBI chr 5:57,358,297...57,372,332
Ensembl chr 5:57,358,327...57,372,239
JBrowse link
G Aqp8 aquaporin 8 multiple interactions
increases transport
affects transport
EXP
ISO
Copper affects the reaction [AQP8 protein affects the transport of Water]; Mercury affects the reaction [AQP8 protein affects the transport of Water]
AQP8 protein results in increased transport of Water
Mercuric Chloride inhibits the reaction [AQP8 protein results in increased transport of Water]
CTD PMID:18059526, PMID:19840149 NCBI chr 1:193,424,818...193,430,665
Ensembl chr 1:193,424,812...193,430,676
JBrowse link
G Aqp9 aquaporin 9 multiple interactions
increases transport
affects transport
EXP
ISO
CFTR protein promotes the reaction [AQP9 protein affects the transport of Water]; lonidamine inhibits the reaction [CFTR protein promotes the reaction [AQP9 protein affects the transport of Water]]; Mercuric Chloride inhibits the reaction [AQP9 protein results in increased transport of Water]; Mercury inhibits the reaction [AQP9 protein results in increased transport of Water]; Phloretin inhibits the reaction [AQP9 protein results in increased transport of Water]; Phloretin inhibits the reaction [CFTR protein promotes the reaction [AQP9 protein affects the transport of Water]] CTD PMID:9514918, PMID:9733774, PMID:10205677, PMID:12606488, PMID:21259319, PMID:22114114 NCBI chr 8:77,559,621...77,599,781
Ensembl chr 8:77,559,624...77,599,781
JBrowse link
G Bcl2 BCL2, apoptosis regulator multiple interactions ISO [[Particulate Matter co-treated with Water] results in increased abundance of Metals] which results in increased expression of BCL2 mRNA CTD PMID:29335169 NCBI chr13:26,605,426...26,769,374
Ensembl chr13:26,605,426...26,769,374
JBrowse link
G Casp1 caspase 1 multiple interactions ISO [[Particulate Matter co-treated with Water] results in increased abundance of Metals] which affects the expression of CASP1 mRNA CTD PMID:29335169 NCBI chr 8:2,605,743...2,614,637
Ensembl chr 8:2,604,962...2,614,631
JBrowse link
G Casp3 caspase 3 multiple interactions EXP [Water deficiency co-treated with Diclofenac] results in increased expression of CASP3 protein; Gum Arabic inhibits the reaction [[Water deficiency co-treated with Diclofenac] results in increased expression of CASP3 protein] CTD PMID:31042592 NCBI chr16:48,845,011...48,863,249
Ensembl chr16:48,845,012...48,863,204
JBrowse link
G Cat catalase multiple interactions EXP
ISO
[Water deficiency co-treated with Diclofenac] results in decreased activity of CAT protein; Gum Arabic inhibits the reaction [[Water deficiency co-treated with Diclofenac] results in decreased activity of CAT protein]
[[Particulate Matter co-treated with Water] results in increased abundance of Metals] which results in increased expression of CAT mRNA
CTD PMID:29335169, PMID:31042592 NCBI chr 3:93,379,872...93,412,058
Ensembl chr 3:93,379,874...93,412,058
JBrowse link
G Ccl2 C-C motif chemokine ligand 2 multiple interactions EXP [Water deficiency co-treated with Diclofenac] results in increased expression of CCL2 protein; Gum Arabic inhibits the reaction [[Water deficiency co-treated with Diclofenac] results in increased expression of CCL2 protein] CTD PMID:31042592 NCBI chr10:69,412,065...69,413,863
Ensembl chr10:69,412,017...69,413,870
JBrowse link
G Cftr CF transmembrane conductance regulator multiple interactions EXP 1-Methyl-3-isobutylxanthine promotes the reaction [CFTR protein affects the transport of Water]; CFTR protein promotes the reaction [AQP9 protein affects the transport of Water]; lonidamine inhibits the reaction [CFTR protein promotes the reaction [AQP9 protein affects the transport of Water]]; N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [CFTR protein affects the transport of Water]; Phloretin inhibits the reaction [CFTR protein promotes the reaction [AQP9 protein affects the transport of Water]] CTD PMID:12606488 NCBI chr 4:42,693,263...42,860,679
Ensembl chr 4:42,692,836...42,860,676
JBrowse link
G Col3a1 collagen type III alpha 1 chain multiple interactions EXP [Water deficiency co-treated with Diclofenac] results in increased expression of COL3A1 protein; Gum Arabic inhibits the reaction [[Water deficiency co-treated with Diclofenac] results in increased expression of COL3A1 protein] CTD PMID:31042592 NCBI chr 9:52,023,295...52,059,221
Ensembl chr 9:52,023,295...52,059,217
JBrowse link
G Cr1l complement C3b/C4b receptor 1 like multiple interactions EXP [Water deficiency co-treated with Diclofenac] results in decreased expression of CR1L protein; Gum Arabic inhibits the reaction [[Water deficiency co-treated with Diclofenac] results in decreased expression of CR1L protein] CTD PMID:31042592 NCBI chr13:113,824,886...113,872,097
Ensembl chr13:113,824,892...113,872,097
JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 multiple interactions ISO [[Particulate Matter co-treated with Water] results in increased abundance of Metals] which results in decreased expression of CYP1A1 mRNA CTD PMID:29335169 NCBI chr 8:62,472,087...62,478,122
Ensembl chr 8:62,472,095...62,478,147
JBrowse link
G Cyp2e1 cytochrome P450, family 2, subfamily e, polypeptide 1 multiple interactions ISO [[Particulate Matter co-treated with Water] results in increased abundance of Metals] which results in decreased expression of CYP2E1 mRNA CTD PMID:29335169 NCBI chr 1:213,511,892...213,522,195
Ensembl chr 1:213,511,874...213,535,542
JBrowse link
G Edn1 endothelin 1 affects export ISO EDN1 protein affects the export of Water CTD PMID:16340664 NCBI chr17:22,136,814...22,143,745
Ensembl chr17:22,137,324...22,143,324
JBrowse link
G Fgf2 fibroblast growth factor 2 increases expression ISO Water results in increased expression of FGF2 mRNA CTD PMID:26800359 NCBI chr 2:124,081,072...124,134,133
Ensembl chr 2:124,081,072...124,134,681
JBrowse link
G Gclc glutamate-cysteine ligase, catalytic subunit multiple interactions ISO [[Particulate Matter co-treated with Water] results in increased abundance of Metals] which results in increased expression of GCLC mRNA CTD PMID:29335169 NCBI chr 8:85,059,051...85,097,471
Ensembl chr 8:85,059,051...85,097,468
JBrowse link
G Gpx1 glutathione peroxidase 1 multiple interactions ISO [[Particulate Matter co-treated with Water] results in increased abundance of Metals] which results in increased expression of GPX1 mRNA CTD PMID:29335169 NCBI chr 8:117,117,430...117,118,528
Ensembl chr 8:117,117,430...117,118,522
JBrowse link
G Gsr glutathione-disulfide reductase multiple interactions ISO [[Particulate Matter co-treated with Water] results in increased abundance of Metals] which results in increased expression of GSR mRNA CTD PMID:29335169 NCBI chr16:62,197,617...62,239,987
Ensembl chr16:62,197,617...62,241,361
JBrowse link
G Hbegf heparin-binding EGF-like growth factor decreases expression ISO Water results in decreased expression of HBEGF mRNA CTD PMID:26800359 NCBI chr18:29,330,302...29,340,185
Ensembl chr18:29,329,764...29,340,403
JBrowse link
G Hmox1 heme oxygenase 1 increases expression
multiple interactions
EXP
ISO
Water deficiency results in increased expression of HMOX1 protein
[[Particulate Matter co-treated with Water] results in increased abundance of Metals] which results in increased expression of HMOX1 mRNA
CTD PMID:22060896, PMID:29335169 NCBI chr19:14,508,634...14,515,455
Ensembl chr19:14,508,616...14,515,456
JBrowse link
G Hpgds hematopoietic prostaglandin D synthase multiple interactions ISO Water affects the reaction [Isoquinolines analog binds to and results in decreased activity of HPGDS protein] CTD PMID:22546671 NCBI chr 4:95,945,356...95,970,666
Ensembl chr 4:95,946,025...95,970,666
JBrowse link
G Il10 interleukin 10 multiple interactions EXP [Gum Arabic co-treated with Water deficiency co-treated with Diclofenac] results in increased expression of IL10 protein CTD PMID:31042592 NCBI chr13:47,738,933...47,743,392
Ensembl chr13:47,739,526...47,743,392
JBrowse link
G Il1b interleukin 1 beta multiple interactions EXP
ISO
[Water deficiency co-treated with Diclofenac] results in increased expression of IL1B protein; Gum Arabic inhibits the reaction [[Water deficiency co-treated with Diclofenac] results in increased expression of IL1B protein]
[[Particulate Matter co-treated with Water] results in increased abundance of Metals] which results in increased expression of IL1B mRNA
CTD PMID:29335169, PMID:31042592 NCBI chr 3:121,876,256...121,882,637
Ensembl chr 3:121,876,263...121,882,726
JBrowse link
G Mt2A metallothionein 2A multiple interactions ISO [[Particulate Matter co-treated with Water] results in increased abundance of Metals] which affects the expression of MT2 mRNA CTD PMID:29335169 NCBI chr19:11,307,966...11,308,740
Ensembl chr19:11,307,967...11,308,740
JBrowse link
G Nfe2l2 nuclear factor, erythroid 2-like 2 multiple interactions ISO [[Particulate Matter co-treated with Water] results in increased abundance of Metals] which results in increased expression of NFE2L2 mRNA CTD PMID:29335169 NCBI chr 3:62,497,568...62,525,146
Ensembl chr 3:62,497,571...62,524,996
JBrowse link
G Nos2 nitric oxide synthase 2 multiple interactions ISO [[Particulate Matter co-treated with Water] results in increased abundance of Metals] which results in increased expression of NOS2 mRNA CTD PMID:29335169 NCBI chr10:66,188,290...66,221,621
Ensembl chr10:66,189,786...66,313,190
JBrowse link
G Nqo1 NAD(P)H quinone dehydrogenase 1 multiple interactions ISO [[Particulate Matter co-treated with Water] results in increased abundance of Metals] which results in increased expression of NQO1 mRNA CTD PMID:29335169 NCBI chr19:38,422,210...38,437,103
Ensembl chr19:38,422,164...38,437,180
JBrowse link
G Slc12a1 solute carrier family 12 member 1 multiple interactions
increases import
EXP [Glucose results in increased activity of SLC12A1 protein] which results in increased import of Water; [Mannitol results in increased activity of SLC12A1 protein] which results in increased import of Water
SLC12A1 protein results in increased import of Water
CTD PMID:12433675 NCBI chr 3:117,421,531...117,498,372
Ensembl chr 3:117,421,604...117,498,367
JBrowse link
G Slc5a3 solute carrier family 5 member 3 increases expression ISO Water deficiency results in increased expression of SLC5A3 mRNA CTD PMID:21219332 NCBI chr11:32,229,366...32,231,812 JBrowse link
G Sod1 superoxide dismutase 1 multiple interactions ISO [[Particulate Matter co-treated with Water] results in increased abundance of Metals] which results in increased expression of SOD1 mRNA CTD PMID:29335169 NCBI chr11:30,363,282...30,368,858
Ensembl chr11:30,363,280...30,368,862
JBrowse link
G Sod2 superoxide dismutase 2 increases expression
multiple interactions
ISO Water deficiency results in increased expression of SOD2 protein
[[Particulate Matter co-treated with Water] results in increased abundance of Metals] which results in increased expression of SOD2 mRNA
CTD PMID:22718889, PMID:29335169 NCBI chr 1:47,914,757...47,921,587
Ensembl chr 1:47,914,759...47,921,587
JBrowse link
G Tac1 tachykinin, precursor 1 multiple interactions EXP TAC1 protein alternative form inhibits the reaction [Cholera Toxin results in increased secretion of Water]; TAC1 protein inhibits the reaction [Cholera Toxin results in increased secretion of Water] CTD PMID:11040190 NCBI chr 4:33,638,853...33,646,819
Ensembl chr 4:33,638,709...33,646,819
JBrowse link
G Tnf tumor necrosis factor multiple interactions EXP [Water deficiency co-treated with Diclofenac] results in increased expression of TNF protein; Gum Arabic inhibits the reaction [[Water deficiency co-treated with Diclofenac] results in increased expression of TNF protein] CTD PMID:31042592 NCBI chr20:5,189,382...5,192,000
Ensembl chr20:5,189,390...5,192,000
JBrowse link
carbidopa term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Comt catechol-O-methyltransferase increases methylation ISO
EXP
COMT protein results in increased methylation of Carbidopa CTD PMID:11160877 NCBI chr11:86,715,981...86,735,630
Ensembl chr11:86,715,981...86,735,622
JBrowse link
ceftazidime pentahydrate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcc4 ATP binding cassette subfamily C member 4 increases transport ISO ABCC4 protein results in increased transport of Ceftazidime CTD PMID:17939016 NCBI chr15:103,695,415...103,927,980
Ensembl chr15:103,696,557...103,927,592
JBrowse link
G Dhfr dihydrofolate reductase decreases activity ISO Ceftazidime results in decreased activity of DHFR protein CTD PMID:25418905 NCBI chr 2:21,931,887...21,958,927
Ensembl chr 2:21,931,493...21,962,453
JBrowse link
G Il10 interleukin 10 multiple interactions ISO Ceftazidime inhibits the reaction [Lipopolysaccharides results in increased secretion of IL10 protein] CTD PMID:16939481 NCBI chr13:47,738,933...47,743,392
Ensembl chr13:47,739,526...47,743,392
JBrowse link
cilazapril monohydrate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ace angiotensin I converting enzyme affects response to substance ISO ACE gene polymorphism affects the susceptibility to Cilazapril CTD PMID:15498266 NCBI chr10:94,170,766...94,213,831
Ensembl chr10:94,170,766...94,187,822
JBrowse link
G Adipoq adiponectin, C1Q and collagen domain containing increases expression ISO Cilazapril results in increased expression of ADIPOQ protein CTD PMID:19789415 NCBI chr11:81,330,845...81,344,488
Ensembl chr11:81,330,293...81,344,488
JBrowse link
G Agtr1a angiotensin II receptor, type 1a multiple interactions EXP [Cilazapril co-treated with Losartan] promotes the reaction [Doxorubicin results in increased expression of AGTR1 mRNA]; Cilazapril promotes the reaction [Doxorubicin results in increased expression of AGTR1 mRNA] CTD PMID:15331931 NCBI chr17:35,907,102...35,958,136
Ensembl chr17:35,907,108...35,958,077
JBrowse link
G Agtr2 angiotensin II receptor, type 2 multiple interactions EXP [Losartan co-treated with Cilazapril] inhibits the reaction [Doxorubicin results in decreased expression of AGTR2 mRNA]; Cilazapril inhibits the reaction [Doxorubicin results in decreased expression of AGTR2 mRNA] CTD PMID:15331931 NCBI chr  X:119,389,480...119,393,845
Ensembl chr  X:119,390,013...119,393,842
JBrowse link
G Fgf2 fibroblast growth factor 2 decreases expression EXP Cilazapril results in decreased expression of FGF2 mRNA; Cilazapril results in decreased expression of FGF2 protein CTD PMID:9640960 NCBI chr 2:124,081,072...124,134,133
Ensembl chr 2:124,081,072...124,134,681
JBrowse link
G Nppa natriuretic peptide A multiple interactions
affects secretion
ISO [Cilazapril co-treated with Verapamil] affects the secretion of NPPA protein
Cilazapril affects the secretion of NPPA protein
CTD PMID:1457087 NCBI chr 5:164,808,407...164,809,716
Ensembl chr 5:164,808,323...164,809,705
JBrowse link
G Ren renin increases activity EXP Cilazapril results in increased activity of REN protein CTD PMID:2425185 NCBI chr13:50,502,724...50,513,953
Ensembl chr13:50,502,724...50,514,151
JBrowse link
G Slc15a1 solute carrier family 15 member 1 multiple interactions ISO Cilazapril inhibits the reaction [SLC15A1 protein results in increased uptake of glycylsarcosine] CTD PMID:18713951 NCBI chr15:106,800,081...106,844,668
Ensembl chr15:106,800,081...106,844,426
JBrowse link
G Slc15a2 solute carrier family 15 member 2 multiple interactions EXP Cilazapril inhibits the reaction [SLC15A2 protein results in increased uptake of glycylsarcosine] CTD PMID:18713951 NCBI chr11:66,932,664...66,961,708
Ensembl chr11:66,932,614...66,961,713
JBrowse link
G Tgfb1 transforming growth factor, beta 1 multiple interactions EXP [Losartan co-treated with Cilazapril] inhibits the reaction [Doxorubicin results in increased expression of TGFB1 protein]; Cilazapril inhibits the reaction [Doxorubicin results in increased expression of TGFB1 protein] CTD PMID:15331931 NCBI chr 1:82,480,875...82,497,196
Ensembl chr 1:82,480,195...82,497,199
JBrowse link
dipotassium bis[mu-tartrato(4-)]diantimonate(2-) trihydrate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G A2m alpha-2-macroglobulin decreases expression ISO Antimony Potassium Tartrate results in decreased expression of A2M mRNA CTD PMID:17547211 NCBI chr 4:154,309,426...154,359,138
Ensembl chr 4:154,309,426...154,359,137
JBrowse link
G Abcc1 ATP binding cassette subfamily C member 1 affects response to substance
decreases response to substance
increases secretion
multiple interactions
ISO ABCC1 protein affects the susceptibility to Antimony Potassium Tartrate
ABCC1 protein results in decreased susceptibility to Antimony Potassium Tartrate
ABCC1 protein results in increased secretion of Antimony Potassium Tartrate
[MYCN protein affects the expression of ABCC1 mRNA] which affects the susceptibility to Antimony Potassium Tartrate; Glutathione affects the reaction [ABCC1 protein results in increased secretion of Antimony Potassium Tartrate]; verlukast inhibits the reaction [ABCC1 protein results in decreased susceptibility to Antimony Potassium Tartrate]; verlukast inhibits the reaction [ABCC1 protein results in increased secretion of Antimony Potassium Tartrate]
CTD PMID:10025956, PMID:10348353, PMID:11278867, PMID:12018890, PMID:12731862 NCBI chr10:549,537...672,235
Ensembl chr10:549,883...672,196
JBrowse link
G Abcc2 ATP binding cassette subfamily C member 2 increases expression EXP Antimony Potassium Tartrate results in increased expression of ABCC2 mRNA; Antimony Potassium Tartrate results in increased expression of ABCC2 protein CTD PMID:11408547 NCBI chr 1:263,554,426...263,612,556
Ensembl chr 1:263,554,453...263,613,252
JBrowse link
G Acp2 acid phosphatase 2, lysosomal decreases expression ISO Antimony Potassium Tartrate results in decreased expression of ACP2 mRNA CTD PMID:17547211 NCBI chr 3:80,020,346...80,030,365
Ensembl chr 3:80,021,440...80,030,363
JBrowse link
G Acsl1 acyl-CoA synthetase long-chain family member 1 decreases expression ISO Antimony Potassium Tartrate results in decreased expression of ACSL1 mRNA CTD PMID:17547211 NCBI chr16:48,937,456...49,003,898
Ensembl chr16:48,937,456...49,003,246
JBrowse link
G Adm adrenomedullin increases expression ISO Antimony Potassium Tartrate results in increased expression of ADM mRNA CTD PMID:17547211 NCBI chr 1:175,443,189...175,447,260
Ensembl chr 1:175,445,088...175,447,259
JBrowse link
G Akr1b1 aldo-keto reductase family 1 member B decreases expression
increases expression
ISO Antimony Potassium Tartrate results in decreased expression of AKR1B1 mRNA
Antimony Potassium Tartrate results in increased expression of AKR1B1 mRNA
CTD PMID:17547211, PMID:28713220 NCBI chr 4:61,706,866...61,720,959
Ensembl chr 4:61,706,864...61,720,956
JBrowse link
G Akr1b10 aldo-keto reductase family 1 member B10 increases expression ISO Antimony Potassium Tartrate results in increased expression of AKR1B10 mRNA CTD PMID:28713220 NCBI chr 4:61,813,265...61,830,371
Ensembl chr 4:61,771,970...61,828,657
JBrowse link
G Akr1c2 aldo-keto reductase family 1, member C2 increases expression ISO Antimony Potassium Tartrate results in increased expression of AKR1C2 protein CTD PMID:28713220 NCBI chr17:69,388,337...69,435,160
Ensembl chr17:69,388,335...69,404,341
JBrowse link
G Akr1c3 aldo-keto reductase family 1, member C3 increases expression ISO Antimony Potassium Tartrate results in increased expression of AKR1C3 mRNA; Antimony Potassium Tartrate results in increased expression of AKR1C3 protein CTD PMID:28713220 NCBI chr17:69,761,126...69,778,021
Ensembl chr17:69,761,118...69,778,021
JBrowse link
G Aldh6a1 aldehyde dehydrogenase 6 family, member A1 decreases expression ISO Antimony Potassium Tartrate results in decreased expression of ALDH6A1 mRNA CTD PMID:17547211 NCBI chr 6:108,146,552...108,167,185
Ensembl chr 6:108,146,582...108,167,185
JBrowse link
G Aldoa aldolase, fructose-bisphosphate A increases expression ISO Antimony Potassium Tartrate results in increased expression of ALDOA mRNA CTD PMID:28713220 NCBI chr 1:198,228,387...198,233,988
Ensembl chr 1:198,228,387...198,233,588
JBrowse link
G Aldoc aldolase, fructose-bisphosphate C increases expression ISO Antimony Potassium Tartrate results in increased expression of ALDOC mRNA CTD PMID:28713220 NCBI chr10:65,586,504...65,590,093
Ensembl chr10:65,586,504...65,590,126
JBrowse link
G Ar androgen receptor increases phosphorylation ISO Antimony Potassium Tartrate results in increased phosphorylation of AR protein CTD PMID:29462692 NCBI chr  X:67,656,253...67,828,998
Ensembl chr  X:67,656,253...67,829,026
JBrowse link
G Atp2b1 ATPase plasma membrane Ca2+ transporting 1 decreases expression ISO Antimony Potassium Tartrate results in decreased expression of ATP2B1 mRNA CTD PMID:17547211 NCBI chr 7:41,114,606...41,223,138
Ensembl chr 7:41,114,697...41,220,579
JBrowse link
G Azgp1 alpha-2-glycoprotein 1, zinc-binding decreases expression ISO Antimony Potassium Tartrate results in decreased expression of AZGP1 mRNA CTD PMID:17547211 NCBI chr12:19,196,565...19,203,094
Ensembl chr12:19,196,611...19,202,647
JBrowse link
G Bmp6 bone morphogenetic protein 6 multiple interactions ISO Antimony Potassium Tartrate inhibits the reaction [BMP6 protein results in increased expression of DUSP12 mRNA]; Antimony Potassium Tartrate inhibits the reaction [BMP6 protein results in increased expression of DUSP2 mRNA] CTD PMID:28713220 NCBI chr17:26,955,142...27,112,820
Ensembl chr17:26,955,142...27,112,820
JBrowse link
G Calml5 calmodulin-like 5 decreases expression ISO Antimony Potassium Tartrate results in decreased expression of CALML5 mRNA CTD PMID:28713220 NCBI chr17:70,044,956...70,045,886 JBrowse link
G Ccnb2 cyclin B2 increases expression ISO Antimony Potassium Tartrate results in increased expression of CCNB2 mRNA CTD PMID:17547211 NCBI chr 8:76,847,972...76,861,165 JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A increases expression ISO Antimony Potassium Tartrate results in increased expression of CDKN1A mRNA CTD PMID:17547211 NCBI chr20:6,348,422...6,358,864
Ensembl chr20:6,351,458...6,358,864
JBrowse link
G Cdkn3 cyclin-dependent kinase inhibitor 3 increases expression ISO Antimony Potassium Tartrate results in increased expression of CDKN3 mRNA CTD PMID:17547211 NCBI chr15:23,553,171...23,564,538
Ensembl chr15:23,553,128...23,564,535
JBrowse link
G Cfb complement factor B decreases expression ISO Antimony Potassium Tartrate results in decreased expression of CFB mRNA CTD PMID:17547211 NCBI chr20:4,536,206...4,542,073
Ensembl chr20:4,536,203...4,561,066
Ensembl chr20:4,536,203...4,561,066
JBrowse link
G Cks2 CDC28 protein kinase regulatory subunit 2 increases expression ISO Antimony Potassium Tartrate results in increased expression of CKS2 mRNA CTD PMID:17547211 NCBI chr17:13,587,664...13,593,423
Ensembl chr17:13,587,665...13,593,423
JBrowse link
G Clgn calmegin decreases expression ISO Antimony Potassium Tartrate results in decreased expression of CLGN mRNA CTD PMID:17547211 NCBI chr19:24,545,257...24,578,527
Ensembl chr19:24,545,318...24,576,798
JBrowse link
G Clptm1 CLPTM1 regulator of GABA type A receptor forward trafficking decreases expression ISO Antimony Potassium Tartrate results in decreased expression of CLPTM1 mRNA CTD PMID:17547211 NCBI chr 1:80,549,051...80,580,665
Ensembl chr 1:80,549,043...80,580,662
JBrowse link
G Dazap1 DAZ associated protein 1 increases expression ISO Antimony Potassium Tartrate results in increased expression of DAZAP1 mRNA CTD PMID:17547211 NCBI chr 7:12,289,895...12,315,897
Ensembl chr 7:12,290,402...12,311,149
JBrowse link
G Dcp1a decapping mRNA 1A increases expression ISO Antimony Potassium Tartrate results in increased expression of DCP1A mRNA CTD PMID:17547211 NCBI chr16:6,542,415...6,583,856
Ensembl chr16:6,542,216...6,587,619
JBrowse link
G Dsc1 desmocollin 1 decreases expression ISO Antimony Potassium Tartrate results in decreased expression of DSC1 mRNA CTD PMID:28713220 NCBI chr18:11,877,918...11,906,828
Ensembl chr18:11,877,561...11,906,827
JBrowse link
G Dst dystonin decreases expression ISO Antimony Potassium Tartrate results in decreased expression of DST protein CTD PMID:28713220 NCBI chr 9:37,902,336...38,296,961
Ensembl chr 9:37,902,303...38,196,273
JBrowse link
G Duox1 dual oxidase 1 multiple interactions
decreases expression
ISO Antimony Potassium Tartrate inhibits the reaction [IL4 protein results in increased expression of DUOX1 mRNA]
Antimony Potassium Tartrate results in decreased expression of DUOX1 mRNA
CTD PMID:29031483 NCBI chr 3:114,251,794...114,286,827
Ensembl chr 3:114,253,637...114,286,802
JBrowse link
G Duoxa1 dual oxidase maturation factor 1 decreases expression ISO Antimony Potassium Tartrate results in decreased expression of DUOXA1 mRNA CTD PMID:29031483 NCBI chr 3:114,241,057...114,251,720
Ensembl chr 3:114,241,057...114,251,647
JBrowse link
G Dusp1 dual specificity phosphatase 1 increases expression ISO Antimony Potassium Tartrate results in increased expression of DUSP1 mRNA CTD PMID:17547211 NCBI chr10:16,970,642...16,973,425
Ensembl chr10:16,970,626...16,973,418
JBrowse link
G Dusp12 dual specificity phosphatase 12 multiple interactions ISO Antimony Potassium Tartrate inhibits the reaction [BMP6 protein results in increased expression of DUSP12 mRNA] CTD PMID:28713220 NCBI chr13:89,258,309...89,267,402
Ensembl chr13:89,258,310...89,267,402
JBrowse link
G Dusp2 dual specificity phosphatase 2 multiple interactions ISO Antimony Potassium Tartrate inhibits the reaction [BMP6 protein results in increased expression of DUSP2 mRNA] CTD PMID:28713220 NCBI chr 3:119,776,925...119,779,110
Ensembl chr 3:119,776,925...119,779,099
JBrowse link
G F5 coagulation factor V decreases expression ISO Antimony Potassium Tartrate results in decreased expression of F5 mRNA CTD PMID:17547211 NCBI chr13:82,479,997...82,535,540
Ensembl chr13:82,479,998...82,535,534
JBrowse link
G Fabp5 fatty acid binding protein 5 decreases expression ISO Antimony Potassium Tartrate results in decreased expression of FABP5 mRNA CTD PMID:28713220 NCBI chr 2:93,981,662...93,985,322
Ensembl chr 2:93,981,656...93,985,378
JBrowse link
G Fdft1 farnesyl diphosphate farnesyl transferase 1 decreases expression ISO Antimony Potassium Tartrate results in decreased expression of FDFT1 mRNA CTD PMID:17547211 NCBI chr15:46,339,248...46,367,302
Ensembl chr15:46,339,249...46,367,302
JBrowse link
G Fdps farnesyl diphosphate synthase decreases expression ISO Antimony Potassium Tartrate results in decreased expression of FDPS mRNA CTD PMID:17547211 NCBI chr 2:188,403,595...188,413,219
Ensembl chr 2:188,392,858...188,413,219
JBrowse link
G Flg filaggrin decreases expression ISO Antimony Potassium Tartrate results in decreased expression of FLG mRNA CTD PMID:28713220 NCBI chr 2:193,565,401...193,574,297 JBrowse link
G Fosl1 FOS like 1, AP-1 transcription factor subunit increases expression ISO Antimony Potassium Tartrate results in increased expression of FOSL1 mRNA CTD PMID:17547211 NCBI chr 1:220,826,560...220,835,066
Ensembl chr 1:220,826,560...220,835,066
JBrowse link
G Fth1 ferritin heavy chain 1 increases expression ISO Antimony Potassium Tartrate results in increased expression of FTH1 mRNA; Antimony Potassium Tartrate results in increased expression of FTH1 protein CTD PMID:28713220 NCBI chr 1:226,030,940...226,033,228
Ensembl chr 1:226,030,938...226,033,228
JBrowse link
G Ftl1 ferritin light chain 1 increases expression ISO Antimony Potassium Tartrate results in increased expression of FTL mRNA CTD PMID:28713220 NCBI chr 1:101,448,190...101,450,034
Ensembl chr 1:101,448,346...101,449,829
JBrowse link
G G6pd glucose-6-phosphate dehydrogenase increases expression ISO Antimony Potassium Tartrate results in increased expression of G6PD mRNA; Antimony Potassium Tartrate results in increased expression of G6PD protein CTD PMID:28713220 NCBI chr  X:156,274,800...156,293,935
Ensembl chr  X:156,274,800...156,293,926
JBrowse link
G Gapdh glyceraldehyde-3-phosphate dehydrogenase increases expression ISO Antimony Potassium Tartrate results in increased expression of GAPDH mRNA CTD PMID:28713220 NCBI chr 4:157,676,336...157,680,322
Ensembl chr 4:157,676,595...157,679,962
JBrowse link
G Gclc glutamate-cysteine ligase, catalytic subunit increases expression ISO Antimony Potassium Tartrate results in increased expression of GCLC mRNA; Antimony Potassium Tartrate results in increased expression of GCLC protein CTD PMID:28713220 NCBI chr 8:85,059,051...85,097,471
Ensembl chr 8:85,059,051...85,097,468
JBrowse link
G Gclm glutamate cysteine ligase, modifier subunit increases expression ISO Antimony Potassium Tartrate results in increased expression of GCLM mRNA CTD PMID:28713220 NCBI chr 2:225,827,504...225,847,876
Ensembl chr 2:225,827,504...225,847,874
JBrowse link
G Gcnt3 glucosaminyl (N-acetyl) transferase 3, mucin type increases expression ISO Antimony Potassium Tartrate results in increased expression of GCNT3 mRNA CTD PMID:17547211 NCBI chr 8:76,449,078...76,459,431
Ensembl chr 8:76,449,081...76,452,554
JBrowse link
G Ghitm growth hormone inducible transmembrane protein decreases expression ISO Antimony Potassium Tartrate results in decreased expression of GHITM mRNA CTD PMID:17547211 NCBI chr16:14,370,269...14,382,647
Ensembl chr16:14,371,531...14,382,641
JBrowse link
G Gla galactosidase, alpha increases expression ISO Antimony Potassium Tartrate results in increased expression of GLA mRNA CTD PMID:17547211 NCBI chr  X:105,405,915...105,417,331
Ensembl chr  X:105,406,792...105,417,323
JBrowse link
G Gtpbp6 GTP binding protein 6 (putative) increases expression ISO Antimony Potassium Tartrate results in increased expression of GTPBP6 mRNA CTD PMID:17547211 NCBI chr12:52,637,000...52,640,869
Ensembl chr12:52,637,000...52,640,839
JBrowse link
G Hmga1 high mobility group AT-hook 1 increases expression ISO Antimony Potassium Tartrate results in increased expression of HMGA1 mRNA CTD PMID:17547211 NCBI chr20:7,132,501...7,140,155
Ensembl chr20:7,136,007...7,138,980
JBrowse link
G Hmox1 heme oxygenase 1 increases expression ISO Antimony Potassium Tartrate results in increased expression of HMOX1 mRNA; Antimony Potassium Tartrate results in increased expression of HMOX1 protein CTD PMID:17547211, PMID:28713220 NCBI chr19:14,508,634...14,515,455
Ensembl chr19:14,508,616...14,515,456
JBrowse link
G Hsd17b2 hydroxysteroid (17-beta) dehydrogenase 2 decreases expression ISO Antimony Potassium Tartrate results in decreased expression of HSD17B2 mRNA CTD PMID:17547211 NCBI chr19:50,246,404...50,317,892
Ensembl chr19:50,246,402...50,317,891
JBrowse link
G Hsd17b7 hydroxysteroid (17-beta) dehydrogenase 7 decreases expression ISO Antimony Potassium Tartrate results in decreased expression of HSD17B7 mRNA CTD PMID:17547211 NCBI chr13:88,288,116...88,308,019
Ensembl chr13:88,288,046...88,307,988
JBrowse link
G Ier2 immediate early response 2 increases expression ISO Antimony Potassium Tartrate results in increased expression of IER2 mRNA CTD PMID:17547211 NCBI chr19:25,774,146...25,775,670
Ensembl chr19:25,774,143...25,775,659
JBrowse link
G Ifrd1 interferon-related developmental regulator 1 decreases expression ISO Antimony Potassium Tartrate results in decreased expression of IFRD1 mRNA CTD PMID:17547211 NCBI chr 6:60,132,025...60,151,354
Ensembl chr 6:60,132,024...60,151,420
JBrowse link
G Il4 interleukin 4 multiple interactions ISO Antimony Potassium Tartrate inhibits the reaction [IL4 protein results in increased expression of DUOX1 mRNA] CTD PMID:29031483 NCBI chr10:38,963,979...38,969,531
Ensembl chr10:38,963,979...38,969,531
JBrowse link
G Ing3 inhibitor of growth family, member 3 increases expression ISO Antimony Potassium Tartrate results in increased expression of ING3 mRNA CTD PMID:17547211 NCBI chr 4:49,017,235...49,044,450
Ensembl chr 4:49,017,311...49,042,990
JBrowse link
G Itgb3bp integrin subunit beta 3 binding protein increases expression ISO Antimony Potassium Tartrate results in increased expression of ITGB3BP mRNA CTD PMID:17547211 NCBI chr 5:118,476,410...118,541,928
Ensembl chr 5:118,476,430...118,673,780
JBrowse link
G Itih3 inter-alpha trypsin inhibitor, heavy chain 3 decreases expression ISO Antimony Potassium Tartrate results in decreased expression of ITIH3 mRNA CTD PMID:17547211 NCBI chr16:6,983,779...7,007,288
Ensembl chr16:6,992,062...7,007,287
JBrowse link
G Ivl involucrin decreases expression ISO Antimony Potassium Tartrate results in decreased expression of IVL mRNA; Antimony Potassium Tartrate results in decreased expression of IVL protein CTD PMID:28713220 NCBI chr 2:192,761,171...192,773,346
Ensembl chr 2:192,761,538...192,763,577
JBrowse link
G Klf6 Kruppel-like factor 6 increases expression ISO Antimony Potassium Tartrate results in increased expression of KLF6 mRNA CTD PMID:17547211 NCBI chr17:67,887,939...67,945,052
Ensembl chr17:67,887,939...67,945,037
JBrowse link
G Krt10 keratin 10 decreases expression ISO Antimony Potassium Tartrate results in decreased expression of KRT10 mRNA; Antimony Potassium Tartrate results in decreased expression of KRT10 protein CTD PMID:28713220 NCBI chr10:87,296,445...87,301,307
Ensembl chr10:87,296,451...87,300,736
JBrowse link
G Krtdap keratinocyte differentiation associated protein decreases expression ISO Antimony Potassium Tartrate results in decreased expression of KRTDAP mRNA CTD PMID:28713220 NCBI chr 1:89,234,689...89,235,610
Ensembl chr 1:89,232,439...89,235,598
JBrowse link
G Lipa lipase A, lysosomal acid type decreases expression ISO Antimony Potassium Tartrate results in decreased expression of LIPA mRNA CTD PMID:17547211 NCBI chr 1:252,816,536...252,959,348
Ensembl chr 1:252,816,527...252,849,904
JBrowse link
G Lrig1 leucine-rich repeats and immunoglobulin-like domains 1 decreases expression ISO Antimony Potassium Tartrate results in decreased expression of LRIG1 mRNA CTD PMID:28713220 NCBI chr 4:126,615,998...126,717,434
Ensembl chr 4:126,617,244...126,644,895
JBrowse link
G Lss lanosterol synthase decreases expression ISO Antimony Potassium Tartrate results in decreased expression of LSS mRNA CTD PMID:17547211 NCBI chr20:12,844,522...12,870,474
Ensembl chr20:12,842,884...12,870,497
JBrowse link
G Maff MAF bZIP transcription factor F increases expression ISO Antimony Potassium Tartrate results in increased expression of MAFF mRNA CTD PMID:17547211 NCBI chr 7:120,580,743...120,592,095
Ensembl chr 7:120,580,743...120,592,095
JBrowse link
G Man1a2 mannosidase, alpha, class 1A, member 2 decreases expression ISO Antimony Potassium Tartrate results in decreased expression of MAN1A2 mRNA CTD PMID:17547211 NCBI chr 2:202,891,537...203,043,847
Ensembl chr 2:202,891,537...203,043,847
JBrowse link
G Mcm2 minichromosome maintenance complex component 2 increases expression ISO Antimony Potassium Tartrate results in increased expression of MCM2 mRNA CTD PMID:17547211 NCBI chr 4:120,825,699...120,840,221
Ensembl chr 4:120,825,699...120,840,111
JBrowse link
G Me1 malic enzyme 1 increases expression ISO Antimony Potassium Tartrate results in increased expression of ME1 mRNA CTD PMID:28713220 NCBI chr 8:94,256,830...94,368,834
Ensembl chr 8:94,256,839...94,368,834
JBrowse link
G Mgat2 alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase decreases expression ISO Antimony Potassium Tartrate results in decreased expression of MGAT2 mRNA CTD PMID:17547211 NCBI chr 6:91,476,698...91,479,187
Ensembl chr 6:91,476,698...91,479,183
JBrowse link
G Mt2A metallothionein 2A increases expression ISO Antimony Potassium Tartrate results in increased expression of MT2A mRNA CTD PMID:28713220 NCBI chr19:11,307,966...11,308,740
Ensembl chr19:11,307,967...11,308,740
JBrowse link
G Mycn MYCN proto-oncogene, bHLH transcription factor multiple interactions
decreases response to substance
ISO [MYCN protein affects the expression of ABCC1 mRNA] which affects the susceptibility to Antimony Potassium Tartrate
MYCN protein results in decreased susceptibility to Antimony Potassium Tartrate
CTD PMID:10348353 NCBI chr 6:38,222,554...38,228,419
Ensembl chr 6:38,222,555...38,228,379
JBrowse link
G Ndrg2 NDRG family member 2 decreases expression ISO Antimony Potassium Tartrate results in decreased expression of NDRG2 mRNA CTD PMID:17547211 NCBI chr15:28,305,820...28,314,459
Ensembl chr15:28,305,821...28,314,459
JBrowse link
G Nfkbia NFKB inhibitor alpha decreases expression ISO Antimony Potassium Tartrate results in decreased expression of NFKBIA mRNA CTD PMID:17547211 NCBI chr 6:76,267,227...76,270,457
Ensembl chr 6:76,267,228...76,270,457
JBrowse link
G Nkx3-1 NK3 homeobox 1 increases expression
multiple interactions
ISO Antimony Potassium Tartrate results in increased expression of NKX3-1 mRNA; Antimony Potassium Tartrate results in increased expression of NKX3-1 protein
bicalutamide inhibits the reaction [Antimony Potassium Tartrate results in increased expression of NKX3-1 mRNA]
CTD PMID:29462692 NCBI chr15:51,065,316...51,067,908
Ensembl chr15:51,065,316...51,068,421
JBrowse link
G Nqo1 NAD(P)H quinone dehydrogenase 1 increases expression ISO Antimony Potassium Tartrate results in increased expression of NQO1 mRNA; Antimony Potassium Tartrate results in increased expression of NQO1 protein CTD PMID:28713220 NCBI chr19:38,422,210...38,437,103
Ensembl chr19:38,422,164...38,437,180
JBrowse link
G Nqo2 N-ribosyldihydronicotinamide:quinone reductase 2 increases expression ISO Antimony Potassium Tartrate results in increased expression of NQO2 mRNA CTD PMID:28713220 NCBI chr17:32,131,847...32,158,559
Ensembl chr17:32,132,347...32,158,538
JBrowse link
G Nr0b2 nuclear receptor subfamily 0, group B, member 2 decreases expression ISO Antimony Potassium Tartrate results in decreased expression of NR0B2 mRNA CTD PMID:17547211 NCBI chr 5:151,776,004...151,779,319
Ensembl chr 5:151,776,004...151,779,319
JBrowse link
G Os9 OS9, endoplasmic reticulum lectin decreases expression ISO Antimony Potassium Tartrate results in decreased expression of OS9 mRNA CTD PMID:17547211 NCBI chr 7:70,378,625...70,407,135
Ensembl chr 7:70,380,311...70,407,177
JBrowse link
G Pdia4 protein disulfide isomerase family A, member 4 decreases expression ISO Antimony Potassium Tartrate results in decreased expression of PDIA4 mRNA CTD PMID:17547211 NCBI chr 4:77,470,636...77,489,535
Ensembl chr 4:77,470,636...77,489,535
JBrowse link
G Pgc progastricsin decreases expression ISO Antimony Potassium Tartrate results in decreased expression of PGC mRNA CTD PMID:17547211 NCBI chr 9:15,266,699...15,274,917
Ensembl chr 9:15,266,699...15,274,917
JBrowse link
G Pgd phosphogluconate dehydrogenase increases expression ISO Antimony Potassium Tartrate results in increased expression of PGD protein CTD PMID:28713220 NCBI chr 5:165,966,128...165,982,327 JBrowse link
G Pgm1 phosphoglucomutase 1 increases expression ISO Antimony Potassium Tartrate results in increased expression of PGM1 mRNA CTD PMID:28713220 NCBI chr 5:118,743,632...118,803,055
Ensembl chr 5:118,743,632...118,803,055
JBrowse link
G Pgm3 phosphoglucomutase 3 increases expression ISO Antimony Potassium Tartrate results in increased expression of PGM3 mRNA CTD PMID:28713220 NCBI chr 8:94,225,513...94,243,230
Ensembl chr 8:94,225,515...94,243,215
JBrowse link
G Pml PML nuclear body scaffold affects localization
multiple interactions
increases degradation
ISO Antimony Potassium Tartrate affects the localization of PML protein
Antimony Potassium Tartrate promotes the reaction [SUMO1 protein binds to PML protein]
Antimony Potassium Tartrate results in increased degradation of PML protein mutant form
CTD PMID:9834237 NCBI chr 8:63,002,515...63,034,310
Ensembl chr 8:63,004,870...63,034,226
JBrowse link
G Ppih peptidylprolyl isomerase H increases expression ISO Antimony Potassium Tartrate results in increased expression of PPIH mRNA CTD PMID:17547211 NCBI chr 5:138,343,934...138,361,743
Ensembl chr 5:138,352,916...138,361,702
JBrowse link
G Psph phosphoserine phosphatase decreases expression ISO Antimony Potassium Tartrate results in decreased expression of PSPH mRNA CTD PMID:17547211 NCBI chr12:30,514,128...30,526,551
Ensembl chr12:30,514,112...30,526,557
JBrowse link
G Pttg1 PTTG1 regulator of sister chromatid separation, securin increases expression ISO Antimony Potassium Tartrate results in increased expression of PTTG1 mRNA CTD PMID:17547211 NCBI chr10:29,014,332...29,026,088
Ensembl chr10:29,020,049...29,026,002
JBrowse link
G Rara retinoic acid receptor, alpha increases degradation ISO Antimony Potassium Tartrate results in increased degradation of RARA protein mutant form CTD PMID:9834237 NCBI chr10:86,838,819...86,884,224
Ensembl chr10:86,860,685...86,884,210
JBrowse link
G Rbpms RNA binding protein, mRNA processing factor increases expression ISO Antimony Potassium Tartrate results in increased expression of RBPMS mRNA CTD PMID:17547211 NCBI chr16:61,954,569...62,109,998
Ensembl chr16:61,954,590...62,096,497
JBrowse link
G Rfc2 replication factor C subunit 2 increases expression ISO Antimony Potassium Tartrate results in increased expression of RFC2 mRNA CTD PMID:17547211 NCBI chr12:25,130,375...25,143,480
Ensembl chr12:25,130,377...25,143,480
JBrowse link
G Rnaseh2a ribonuclease H2, subunit A increases expression ISO Antimony Potassium Tartrate results in increased expression of RNASEH2A mRNA CTD PMID:17547211 NCBI chr19:26,074,980...26,084,780
Ensembl chr19:26,074,987...26,084,679
JBrowse link
G Rnh1 ribonuclease/angiogenin inhibitor 1 decreases expression ISO Antimony Potassium Tartrate results in decreased expression of RNH1 protein CTD PMID:28713220 NCBI chr 1:214,151,341...214,163,807
Ensembl chr 1:214,151,338...214,163,808
JBrowse link
G Rptn repetin decreases expression ISO Antimony Potassium Tartrate results in decreased expression of RPTN mRNA CTD PMID:28713220 NCBI chr 2:193,722,394...193,729,040
Ensembl chr 2:193,724,248...193,728,302
JBrowse link
G Ryr1 ryanodine receptor 1 decreases expression ISO Antimony Potassium Tartrate results in decreased expression of RYR1 mRNA CTD PMID:28713220 NCBI chr 1:87,959,596...88,066,252
Ensembl chr 1:87,959,712...88,066,101
JBrowse link
G S100a8 S100 calcium binding protein A8 decreases expression ISO Antimony Potassium Tartrate results in decreased expression of S100A8 mRNA; Antimony Potassium Tartrate results in decreased expression of S100A8 protein CTD PMID:28713220 NCBI chr 2:190,073,239...190,074,333
Ensembl chr 2:190,073,815...190,074,354
JBrowse link
G S100a9 S100 calcium binding protein A9 decreases expression ISO Antimony Potassium Tartrate results in decreased expression of S100A9 mRNA; Antimony Potassium Tartrate results in decreased expression of S100A9 protein CTD PMID:28713220 NCBI chr 2:190,097,436...190,100,209
Ensembl chr 2:190,097,554...190,100,276
JBrowse link
G Scd stearoyl-CoA desaturase decreases expression ISO Antimony Potassium Tartrate results in decreased expression of SCD mRNA CTD PMID:17547211 NCBI chr 1:264,159,966...264,173,061
Ensembl chr 1:264,160,129...264,172,729
JBrowse link
G Sephs2 selenophosphate synthetase 2 decreases expression ISO Antimony Potassium Tartrate results in decreased expression of SEPHS2 mRNA CTD PMID:17547211 NCBI chr 1:198,719,158...198,721,476
Ensembl chr 1:198,719,162...198,721,476
JBrowse link
G Serpinb1a serpin family B member 1A decreases expression ISO Antimony Potassium Tartrate results in decreased expression of SERPINB1 mRNA CTD PMID:17547211 NCBI chr17:32,903,089...32,911,498
Ensembl chr17:32,904,119...32,911,495
JBrowse link
G Serpinc1 serpin family C member 1 decreases expression ISO Antimony Potassium Tartrate results in decreased expression of SERPINC1 mRNA CTD PMID:17547211 NCBI chr13:78,806,107...78,820,375
Ensembl chr13:78,805,347...78,833,192
JBrowse link
G Sik1 salt-inducible kinase 1 increases expression ISO Antimony Potassium Tartrate results in increased expression of SIK1 mRNA CTD PMID:17547211 NCBI chr20:10,670,747...10,680,279
Ensembl chr20:10,668,411...10,680,283
JBrowse link
G Snrpa small nuclear ribonucleoprotein polypeptide A increases expression ISO Antimony Potassium Tartrate results in increased expression of SNRPA mRNA CTD PMID:17547211 NCBI chr 1:83,999,670...84,008,429
Ensembl chr 1:83,999,671...84,008,293
JBrowse link
G Sprr1a small proline-rich protein 1A decreases expression ISO Antimony Potassium Tartrate results in decreased expression of SPRR1A mRNA; Antimony Potassium Tartrate results in decreased expression of SPRR1A protein CTD PMID:28713220 NCBI chr 2:192,669,143...192,671,059
Ensembl chr 2:192,669,143...192,671,059
JBrowse link
G Sprr1b small proline-rich protein 1B decreases expression ISO Antimony Potassium Tartrate results in decreased expression of SPRR1B mRNA; Antimony Potassium Tartrate results in decreased expression of SPRR1B protein CTD PMID:28713220 NCBI chr 2:192,622,972...192,624,848
Ensembl chr 2:192,623,244...192,623,681
JBrowse link
G Sprr3 small proline-rich protein 3 decreases expression ISO Antimony Potassium Tartrate results in decreased expression of SPRR3 mRNA; Antimony Potassium Tartrate results in decreased expression of SPRR3 protein CTD PMID:28713220 NCBI chr 2:192,641,472...192,643,942
Ensembl chr 2:192,641,790...192,642,548
JBrowse link
G Sqle squalene epoxidase decreases expression ISO Antimony Potassium Tartrate results in decreased expression of SQLE mRNA CTD PMID:17547211 NCBI chr 7:99,609,929...99,624,803
Ensembl chr 7:99,609,191...99,624,732
JBrowse link
G Srsf1 serine and arginine rich splicing factor 1 decreases expression ISO Antimony Potassium Tartrate results in decreased expression of SRSF1 mRNA CTD PMID:17547211 NCBI chr10:75,334,200...75,341,197
Ensembl chr10:75,335,146...75,341,197
JBrowse link
G Srsf5 serine and arginine rich splicing factor 5 decreases expression ISO Antimony Potassium Tartrate results in decreased expression of SRSF5 mRNA CTD PMID:17547211 NCBI chr 6:104,611,026...104,640,033
Ensembl chr 6:104,611,026...104,615,302
JBrowse link
G Srxn1 sulfiredoxin 1 increases expression ISO Antimony Potassium Tartrate results in increased expression of SRXN1 mRNA CTD PMID:28713220 NCBI chr 3:147,608,850...147,614,410
Ensembl chr 3:147,609,095...147,632,801
JBrowse link
G St6galnac4 ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 4 decreases expression ISO Antimony Potassium Tartrate results in decreased expression of ST6GALNAC4 mRNA CTD PMID:17547211 NCBI chr 3:11,607,103...11,619,595
Ensembl chr 3:11,607,225...11,619,593
JBrowse link
G Sumo1 small ubiquitin-like modifier 1 affects localization
multiple interactions
ISO Antimony Potassium Tartrate affects the localization of SUMO1 protein
Antimony Potassium Tartrate promotes the reaction [SUMO1 protein binds to PML protein]
CTD PMID:9834237 NCBI chr 9:66,453,428...66,483,614
Ensembl chr 9:66,453,438...66,483,614
JBrowse link
G Tardbp TAR DNA binding protein decreases expression ISO Antimony Potassium Tartrate results in decreased expression of TARDBP mRNA CTD PMID:17547211 NCBI chr 5:165,432,089...165,442,232
Ensembl chr 5:165,432,095...165,442,048
JBrowse link
G Tnfaip3 TNF alpha induced protein 3 increases expression ISO Antimony Potassium Tartrate results in increased expression of TNFAIP3 mRNA CTD PMID:17547211 NCBI chr 1:14,401,103...14,416,369
Ensembl chr 1:14,402,913...14,412,807
JBrowse link
G Tnfsf10 TNF superfamily member 10 decreases expression ISO Antimony Potassium Tartrate results in decreased expression of TNFSF10 mRNA CTD PMID:17547211 NCBI chr 2:113,008,008...113,026,899
Ensembl chr 2:113,007,549...113,026,899
JBrowse link
G Tob1 transducer of ErbB-2.1 decreases expression ISO Antimony Potassium Tartrate results in decreased expression of TOB1 mRNA CTD PMID:17547211 NCBI chr10:81,913,689...81,915,727
Ensembl chr10:81,913,689...81,915,716
JBrowse link
G Tpi1 triosephosphate isomerase 1 increases expression ISO Antimony Potassium Tartrate results in increased expression of TPI1 mRNA CTD PMID:28713220 NCBI chr 4:157,328,375...157,331,905
Ensembl chr 4:157,328,379...157,331,905
JBrowse link
G Tspan7 tetraspanin 7 decreases expression ISO Antimony Potassium Tartrate results in decreased expression of TSPAN7 mRNA CTD PMID:17547211 NCBI chr  X:13,261,551...13,282,886
Ensembl chr  X:13,261,558...13,279,099
JBrowse link
G Tuft1 tuftelin 1 increases expression ISO Antimony Potassium Tartrate results in increased expression of TUFT1 mRNA CTD PMID:17547211 NCBI chr 2:195,861,772...195,907,471
Ensembl chr 2:195,861,649...195,908,037
JBrowse link
G Txnrd1 thioredoxin reductase 1 increases expression ISO Antimony Potassium Tartrate results in increased expression of TXNRD1 mRNA CTD PMID:17547211, PMID:28713220 NCBI chr 7:26,946,124...26,984,400
Ensembl chr 7:26,946,125...26,984,400
JBrowse link
G Tyms thymidylate synthetase increases expression ISO Antimony Potassium Tartrate results in increased expression of TYMS mRNA CTD PMID:17547211 NCBI chr 9:121,918,875...121,931,564
Ensembl chr 9:121,918,947...121,931,564
JBrowse link
G Ube2c ubiquitin-conjugating enzyme E2C increases expression ISO Antimony Potassium Tartrate results in increased expression of UBE2C mRNA CTD PMID:17547211 NCBI chr 3:161,236,971...161,239,371
Ensembl chr 3:161,236,898...161,241,159
JBrowse link
G Ugt1a6 UDP glucuronosyltransferase family 1 member A6 increases expression ISO Antimony Potassium Tartrate results in increased expression of UGT1A6 mRNA CTD PMID:28713220 NCBI chr 9:95,241,609...95,302,822
Ensembl chr 9:95,161,157...95,302,822
JBrowse link
G Zwint ZW10 interacting kinetochore protein increases expression ISO Antimony Potassium Tartrate results in increased expression of ZWINT mRNA CTD PMID:17547211 NCBI chr20:17,075,781...17,091,715
Ensembl chr20:17,075,771...17,091,766
JBrowse link
diprotium oxide term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Akt1 AKT serine/threonine kinase 1 multiple interactions ISO [[Particulate Matter co-treated with Water] results in increased abundance of Metals] which results in increased expression of AKT1 mRNA CTD PMID:29335169 NCBI chr 6:137,218,398...137,239,970
Ensembl chr 6:137,218,376...137,236,258
JBrowse link
G Aqp1 aquaporin 1 increases transport
multiple interactions
ISO
EXP
AQP1 protein results in increased transport of Water
Mercuric Chloride inhibits the reaction [AQP1 protein results in increased transport of Water]; Mercury inhibits the reaction [AQP1 protein results in increased transport of Water]
CTD PMID:7528928, PMID:8457558, PMID:10559675, PMID:11035042, PMID:11078688, PMID:21251984, PMID:21259319 NCBI chr 4:85,551,503...85,563,683
Ensembl chr 4:85,551,502...85,569,360
JBrowse link
G Aqp11 aquaporin 11 multiple interactions
increases transport
ISO Mercaptoethanol inhibits the reaction [Mercuric Chloride inhibits the reaction [AQP11 protein results in increased transport of Water]]; Mercuric Chloride inhibits the reaction [AQP11 protein results in increased transport of Water] CTD PMID:21251984 NCBI chr 1:162,703,394...162,713,560
Ensembl chr 1:162,703,442...162,713,610
JBrowse link
G Aqp2 aquaporin 2 increases expression EXP Water deficiency results in increased expression of AQP2 mRNA CTD PMID:15462210 NCBI chr 7:141,237,802...141,242,837
Ensembl chr 7:141,237,768...141,245,165
JBrowse link
G Aqp3 aquaporin 3 (Gill blood group) multiple interactions
increases expression
increases transport
ISO
EXP
Dexamethasone promotes the reaction [AQP3 protein results in increased transport of Water]; Mercaptoethanol inhibits the reaction [Mercuric Chloride inhibits the reaction [AQP3 protein results in increased transport of Water]]; Mercuric Chloride inhibits the reaction [AQP3 protein results in increased transport of Water]; Mercuric Chloride inhibits the reaction [Dexamethasone promotes the reaction [AQP3 protein results in increased transport of Water]]
Water deficiency results in increased expression of AQP3 mRNA; Water deficiency results in increased expression of AQP3 protein
Copper Sulfate inhibits the reaction [AQP3 protein results in increased transport of Water]; Mercuric Chloride inhibits the reaction [AQP3 protein results in increased transport of Water]
CTD PMID:9124401, PMID:9374739, PMID:15462210, PMID:22687538 NCBI chr 5:57,423,735...57,429,252
Ensembl chr 5:57,423,734...57,429,245
JBrowse link
G Aqp4 aquaporin 4 increases transport
increases response to substance
increases expression
affects transport
EXP
ISO
AQP4 protein results in increased transport of Water
AQP4 protein results in increased susceptibility to Water
Water deficiency results in increased expression of AQP4 mRNA
AQP4 protein affects the transport of Water
CTD PMID:7528931, PMID:15462210, PMID:20815926, PMID:21251984 NCBI chr18:6,766,009...6,782,757
Ensembl chr18:6,765,945...6,782,996
JBrowse link
G Aqp7 aquaporin 7 affects transport
increases transport
EXP AQP7 protein affects the transport of Water
AQP7 protein results in increased transport of Water
CTD PMID:9252401, PMID:18059526 NCBI chr 5:57,358,297...57,372,332
Ensembl chr 5:57,358,327...57,372,239
JBrowse link
G Aqp8 aquaporin 8 multiple interactions
increases transport
affects transport
EXP
ISO
Copper affects the reaction [AQP8 protein affects the transport of Water]; Mercury affects the reaction [AQP8 protein affects the transport of Water]
AQP8 protein results in increased transport of Water
Mercuric Chloride inhibits the reaction [AQP8 protein results in increased transport of Water]
CTD PMID:18059526, PMID:19840149 NCBI chr 1:193,424,818...193,430,665
Ensembl chr 1:193,424,812...193,430,676
JBrowse link
G Aqp9 aquaporin 9 multiple interactions
increases transport
affects transport
EXP
ISO
CFTR protein promotes the reaction [AQP9 protein affects the transport of Water]; lonidamine inhibits the reaction [CFTR protein promotes the reaction [AQP9 protein affects the transport of Water]]; Mercuric Chloride inhibits the reaction [AQP9 protein results in increased transport of Water]; Mercury inhibits the reaction [AQP9 protein results in increased transport of Water]; Phloretin inhibits the reaction [AQP9 protein results in increased transport of Water]; Phloretin inhibits the reaction [CFTR protein promotes the reaction [AQP9 protein affects the transport of Water]] CTD PMID:9514918, PMID:9733774, PMID:10205677, PMID:12606488, PMID:21259319, PMID:22114114 NCBI chr 8:77,559,621...77,599,781
Ensembl chr 8:77,559,624...77,599,781
JBrowse link
G Bcl2 BCL2, apoptosis regulator multiple interactions ISO [[Particulate Matter co-treated with Water] results in increased abundance of Metals] which results in increased expression of BCL2 mRNA CTD PMID:29335169 NCBI chr13:26,605,426...26,769,374
Ensembl chr13:26,605,426...26,769,374
JBrowse link
G Casp1 caspase 1 multiple interactions ISO [[Particulate Matter co-treated with Water] results in increased abundance of Metals] which affects the expression of CASP1 mRNA CTD PMID:29335169 NCBI chr 8:2,605,743...2,614,637
Ensembl chr 8:2,604,962...2,614,631
JBrowse link
G Casp3 caspase 3 multiple interactions EXP [Water deficiency co-treated with Diclofenac] results in increased expression of CASP3 protein; Gum Arabic inhibits the reaction [[Water deficiency co-treated with Diclofenac] results in increased expression of CASP3 protein] CTD PMID:31042592 NCBI chr16:48,845,011...48,863,249
Ensembl chr16:48,845,012...48,863,204
JBrowse link
G Cat catalase multiple interactions EXP
ISO
[Water deficiency co-treated with Diclofenac] results in decreased activity of CAT protein; Gum Arabic inhibits the reaction [[Water deficiency co-treated with Diclofenac] results in decreased activity of CAT protein]
[[Particulate Matter co-treated with Water] results in increased abundance of Metals] which results in increased expression of CAT mRNA
CTD PMID:29335169, PMID:31042592 NCBI chr 3:93,379,872...93,412,058
Ensembl chr 3:93,379,874...93,412,058
JBrowse link
G Ccl2 C-C motif chemokine ligand 2 multiple interactions EXP [Water deficiency co-treated with Diclofenac] results in increased expression of CCL2 protein; Gum Arabic inhibits the reaction [[Water deficiency co-treated with Diclofenac] results in increased expression of CCL2 protein] CTD PMID:31042592 NCBI chr10:69,412,065...69,413,863
Ensembl chr10:69,412,017...69,413,870
JBrowse link
G Cftr CF transmembrane conductance regulator multiple interactions EXP 1-Methyl-3-isobutylxanthine promotes the reaction [CFTR protein affects the transport of Water]; CFTR protein promotes the reaction [AQP9 protein affects the transport of Water]; lonidamine inhibits the reaction [CFTR protein promotes the reaction [AQP9 protein affects the transport of Water]]; N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [CFTR protein affects the transport of Water]; Phloretin inhibits the reaction [CFTR protein promotes the reaction [AQP9 protein affects the transport of Water]] CTD PMID:12606488 NCBI chr 4:42,693,263...42,860,679
Ensembl chr 4:42,692,836...42,860,676
JBrowse link
G Col3a1 collagen type III alpha 1 chain multiple interactions EXP [Water deficiency co-treated with Diclofenac] results in increased expression of COL3A1 protein; Gum Arabic inhibits the reaction [[Water deficiency co-treated with Diclofenac] results in increased expression of COL3A1 protein] CTD PMID:31042592 NCBI chr 9:52,023,295...52,059,221
Ensembl chr 9:52,023,295...52,059,217
JBrowse link
G Cr1l complement C3b/C4b receptor 1 like multiple interactions EXP [Water deficiency co-treated with Diclofenac] results in decreased expression of CR1L protein; Gum Arabic inhibits the reaction [[Water deficiency co-treated with Diclofenac] results in decreased expression of CR1L protein] CTD PMID:31042592 NCBI chr13:113,824,886...113,872,097
Ensembl chr13:113,824,892...113,872,097
JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 multiple interactions ISO [[Particulate Matter co-treated with Water] results in increased abundance of Metals] which results in decreased expression of CYP1A1 mRNA CTD PMID:29335169 NCBI chr 8:62,472,087...62,478,122
Ensembl chr 8:62,472,095...62,478,147
JBrowse link
G Cyp2e1 cytochrome P450, family 2, subfamily e, polypeptide 1 multiple interactions ISO [[Particulate Matter co-treated with Water] results in increased abundance of Metals] which results in decreased expression of CYP2E1 mRNA CTD PMID:29335169 NCBI chr 1:213,511,892...213,522,195
Ensembl chr 1:213,511,874...213,535,542
JBrowse link
G Edn1 endothelin 1 affects export ISO EDN1 protein affects the export of Water CTD PMID:16340664 NCBI chr17:22,136,814...22,143,745
Ensembl chr17:22,137,324...22,143,324
JBrowse link
G Fgf2 fibroblast growth factor 2 increases expression ISO Water results in increased expression of FGF2 mRNA CTD PMID:26800359 NCBI chr 2:124,081,072...124,134,133
Ensembl chr 2:124,081,072...124,134,681
JBrowse link
G Gclc glutamate-cysteine ligase, catalytic subunit multiple interactions ISO [[Particulate Matter co-treated with Water] results in increased abundance of Metals] which results in increased expression of GCLC mRNA CTD PMID:29335169 NCBI chr 8:85,059,051...85,097,471
Ensembl chr 8:85,059,051...85,097,468
JBrowse link
G Gpx1 glutathione peroxidase 1 multiple interactions ISO [[Particulate Matter co-treated with Water] results in increased abundance of Metals] which results in increased expression of GPX1 mRNA CTD PMID:29335169 NCBI chr 8:117,117,430...117,118,528
Ensembl chr 8:117,117,430...117,118,522
JBrowse link
G Gsr glutathione-disulfide reductase multiple interactions ISO [[Particulate Matter co-treated with Water] results in increased abundance of Metals] which results in increased expression of GSR mRNA CTD PMID:29335169 NCBI chr16:62,197,617...62,239,987
Ensembl chr16:62,197,617...62,241,361
JBrowse link
G Hbegf heparin-binding EGF-like growth factor decreases expression ISO Water results in decreased expression of HBEGF mRNA CTD PMID:26800359 NCBI chr18:29,330,302...29,340,185
Ensembl chr18:29,329,764...29,340,403
JBrowse link
G Hmox1 heme oxygenase 1 increases expression
multiple interactions
EXP
ISO
Water deficiency results in increased expression of HMOX1 protein
[[Particulate Matter co-treated with Water] results in increased abundance of Metals] which results in increased expression of HMOX1 mRNA
CTD PMID:22060896, PMID:29335169 NCBI chr19:14,508,634...14,515,455
Ensembl chr19:14,508,616...14,515,456
JBrowse link
G Hpgds hematopoietic prostaglandin D synthase multiple interactions ISO Water affects the reaction [Isoquinolines analog binds to and results in decreased activity of HPGDS protein] CTD PMID:22546671 NCBI chr 4:95,945,356...95,970,666
Ensembl chr 4:95,946,025...95,970,666
JBrowse link
G Il10 interleukin 10 multiple interactions EXP [Gum Arabic co-treated with Water deficiency co-treated with Diclofenac] results in increased expression of IL10 protein CTD PMID:31042592 NCBI chr13:47,738,933...47,743,392
Ensembl chr13:47,739,526...47,743,392
JBrowse link
G Il1b interleukin 1 beta multiple interactions EXP
ISO
[Water deficiency co-treated with Diclofenac] results in increased expression of IL1B protein; Gum Arabic inhibits the reaction [[Water deficiency co-treated with Diclofenac] results in increased expression of IL1B protein]
[[Particulate Matter co-treated with Water] results in increased abundance of Metals] which results in increased expression of IL1B mRNA
CTD PMID:29335169, PMID:31042592 NCBI chr 3:121,876,256...121,882,637
Ensembl chr 3:121,876,263...121,882,726
JBrowse link
G Mt2A metallothionein 2A multiple interactions ISO [[Particulate Matter co-treated with Water] results in increased abundance of Metals] which affects the expression of MT2 mRNA CTD PMID:29335169 NCBI chr19:11,307,966...11,308,740
Ensembl chr19:11,307,967...11,308,740
JBrowse link
G Nfe2l2 nuclear factor, erythroid 2-like 2 multiple interactions ISO [[Particulate Matter co-treated with Water] results in increased abundance of Metals] which results in increased expression of NFE2L2 mRNA CTD PMID:29335169 NCBI chr 3:62,497,568...62,525,146
Ensembl chr 3:62,497,571...62,524,996
JBrowse link
G Nos2 nitric oxide synthase 2 multiple interactions ISO [[Particulate Matter co-treated with Water] results in increased abundance of Metals] which results in increased expression of NOS2 mRNA CTD PMID:29335169 NCBI chr10:66,188,290...66,221,621
Ensembl chr10:66,189,786...66,313,190
JBrowse link
G Nqo1 NAD(P)H quinone dehydrogenase 1 multiple interactions ISO [[Particulate Matter co-treated with Water] results in increased abundance of Metals] which results in increased expression of NQO1 mRNA CTD PMID:29335169 NCBI chr19:38,422,210...38,437,103
Ensembl chr19:38,422,164...38,437,180
JBrowse link
G Slc12a1 solute carrier family 12 member 1 multiple interactions
increases import
EXP [Glucose results in increased activity of SLC12A1 protein] which results in increased import of Water; [Mannitol results in increased activity of SLC12A1 protein] which results in increased import of Water
SLC12A1 protein results in increased import of Water
CTD PMID:12433675 NCBI chr 3:117,421,531...117,498,372
Ensembl chr 3:117,421,604...117,498,367
JBrowse link
G Slc5a3 solute carrier family 5 member 3 increases expression ISO Water deficiency results in increased expression of SLC5A3 mRNA CTD PMID:21219332 NCBI chr11:32,229,366...32,231,812 JBrowse link
G Sod1 superoxide dismutase 1 multiple interactions ISO [[Particulate Matter co-treated with Water] results in increased abundance of Metals] which results in increased expression of SOD1 mRNA CTD PMID:29335169 NCBI chr11:30,363,282...30,368,858
Ensembl chr11:30,363,280...30,368,862
JBrowse link
G Sod2 superoxide dismutase 2 increases expression
multiple interactions
ISO Water deficiency results in increased expression of SOD2 protein
[[Particulate Matter co-treated with Water] results in increased abundance of Metals] which results in increased expression of SOD2 mRNA
CTD PMID:22718889, PMID:29335169 NCBI chr 1:47,914,757...47,921,587
Ensembl chr 1:47,914,759...47,921,587
JBrowse link
G Tac1 tachykinin, precursor 1 multiple interactions EXP TAC1 protein alternative form inhibits the reaction [Cholera Toxin results in increased secretion of Water]; TAC1 protein inhibits the reaction [Cholera Toxin results in increased secretion of Water] CTD PMID:11040190 NCBI chr 4:33,638,853...33,646,819
Ensembl chr 4:33,638,709...33,646,819
JBrowse link
G Tnf tumor necrosis factor multiple interactions EXP [Water deficiency co-treated with Diclofenac] results in increased expression of TNF protein; Gum Arabic inhibits the reaction [[Water deficiency co-treated with Diclofenac] results in increased expression of TNF protein] CTD PMID:31042592 NCBI chr20:5,189,382...5,192,000
Ensembl chr20:5,189,390...5,192,000
JBrowse link
enalaprilat dihydrate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ace angiotensin I converting enzyme multiple interactions ISO Enalaprilat inhibits the reaction [Glucose results in increased expression of ACE protein] CTD PMID:16452552 NCBI chr10:94,170,766...94,213,831
Ensembl chr10:94,170,766...94,187,822
JBrowse link
G Adrb1 adrenoceptor beta 1 affects expression EXP Enalaprilat affects the expression of ADRB1 protein CTD PMID:9260993 NCBI chr 1:277,537,585...277,538,985
Ensembl chr 1:277,537,585...277,538,985
JBrowse link
G Adrb2 adrenoceptor beta 2 affects expression EXP Enalaprilat affects the expression of ADRB2 protein CTD PMID:9260993 NCBI chr18:57,513,792...57,515,834
Ensembl chr18:57,513,793...57,515,834
JBrowse link
G Agt angiotensinogen decreases expression
multiple interactions
EXP
ISO
Enalaprilat results in decreased expression of AGT protein modified form
Enalaprilat inhibits the reaction [Glucose results in increased expression of AGT protein]
CTD PMID:16452552, PMID:21795644 NCBI chr19:57,321,594...57,333,460
Ensembl chr19:57,321,640...57,333,433
JBrowse link
G Agtr1a angiotensin II receptor, type 1a multiple interactions ISO Enalaprilat inhibits the reaction [Glucose results in increased expression of AGTR1 protein] CTD PMID:16452552 NCBI chr17:35,907,102...35,958,136
Ensembl chr17:35,907,108...35,958,077
JBrowse link
G Bcl2 BCL2, apoptosis regulator increases expression ISO Enalaprilat results in increased expression of BCL2 mRNA CTD PMID:17342403 NCBI chr13:26,605,426...26,769,374
Ensembl chr13:26,605,426...26,769,374
JBrowse link
G Bdkrb1 bradykinin receptor B1 multiple interactions
increases activity
ISO bradykinin, Lys-Leu(8)-desArg(9)- inhibits the reaction [Enalaprilat results in increased activity of BDKRB1 protein]; Zinc affects the reaction [Enalaprilat results in increased activity of BDKRB1 protein] CTD PMID:11880373 NCBI chr 6:129,437,423...129,441,553
Ensembl chr 6:129,438,158...129,440,574
JBrowse link
G Edn1 endothelin 1 decreases secretion ISO Enalaprilat results in decreased secretion of EDN1 protein CTD PMID:19079593 NCBI chr17:22,136,814...22,143,745
Ensembl chr17:22,137,324...22,143,324
JBrowse link
G Fn1 fibronectin 1 decreases expression
multiple interactions
EXP
ISO
Enalaprilat results in decreased expression of FN1 mRNA; Enalaprilat results in decreased expression of FN1 protein
Enalaprilat inhibits the reaction [Glucose results in increased expression of FN1 mRNA]
CTD PMID:14520012, PMID:21795644 NCBI chr 9:78,900,111...78,969,018
Ensembl chr 9:78,900,103...78,969,078
JBrowse link
G Glud1 glutamate dehydrogenase 1 multiple interactions EXP Enalaprilat inhibits the reaction [Dexamethasone results in decreased expression of GLUD1 mRNA] CTD PMID:32494933 NCBI chr16:10,661,486...10,695,557
Ensembl chr16:10,662,021...10,695,557
JBrowse link
G Grm1 glutamate metabotropic receptor 1 multiple interactions EXP Enalaprilat inhibits the reaction [Dexamethasone results in increased expression of GRM1 mRNA] CTD PMID:32494933 NCBI chr 1:4,753,141...5,165,859
Ensembl chr 1:4,753,144...5,165,859
JBrowse link
G Hmgb1 high mobility group box 1 multiple interactions EXP Enalaprilat inhibits the reaction [Dexamethasone results in increased expression of HMGB1 mRNA]; Enalaprilat inhibits the reaction [Dexamethasone results in increased expression of HMGB1 protein] CTD PMID:32494933 NCBI chr12:7,082,529...7,090,246
Ensembl chr16:37,500,017...37,502,237
JBrowse link
G Ins2 insulin 2 multiple interactions ISO Enalaprilat inhibits the reaction [Glucose results in decreased secretion of INS protein] CTD PMID:16452552 NCBI chr 1:215,856,967...215,858,034
Ensembl chr 1:215,856,971...215,858,034
JBrowse link
G Ppard peroxisome proliferator-activated receptor delta multiple interactions EXP [Enalaprilat co-treated with Daunorubicin] results in increased expression of PPARD mRNA CTD PMID:23834779 NCBI chr20:7,818,289...7,883,482
Ensembl chr20:7,818,289...7,885,333
JBrowse link
G Ren renin increases expression EXP Enalaprilat results in increased expression of REN mRNA CTD PMID:21795644 NCBI chr13:50,502,724...50,513,953
Ensembl chr13:50,502,724...50,514,151
JBrowse link
G Serpine1 serpin family E member 1 decreases expression EXP Enalaprilat results in decreased expression of SERPINE1 mRNA CTD PMID:21795644 NCBI chr12:22,641,104...22,651,482
Ensembl chr12:22,641,104...22,651,482
JBrowse link
G Tgfb1 transforming growth factor, beta 1 decreases expression EXP Enalaprilat results in decreased expression of TGFB1 mRNA; Enalaprilat results in decreased expression of TGFB1 protein CTD PMID:21795644 NCBI chr 1:82,480,875...82,497,196
Ensembl chr 1:82,480,195...82,497,199
JBrowse link
G Tlr4 toll-like receptor 4 multiple interactions EXP Enalaprilat inhibits the reaction [Dexamethasone results in increased expression of TLR4 mRNA] CTD PMID:32494933 NCBI chr 5:82,587,424...82,601,056
Ensembl chr 5:82,587,420...82,601,052
JBrowse link
G Tnf tumor necrosis factor decreases expression ISO Enalaprilat results in decreased expression of TNF mRNA CTD PMID:17342403 NCBI chr20:5,189,382...5,192,000
Ensembl chr20:5,189,390...5,192,000
JBrowse link
gadodiamide hydrate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Akt1 AKT serine/threonine kinase 1 increases phosphorylation
multiple interactions
ISO gadodiamide results in increased phosphorylation of AKT1 protein
2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [gadodiamide results in increased phosphorylation of AKT1 protein]
CTD PMID:19561517 NCBI chr 6:137,218,398...137,239,970
Ensembl chr 6:137,218,376...137,236,258
JBrowse link
G Aldh1a1 aldehyde dehydrogenase 1 family, member A1 increases expression ISO gadodiamide results in increased expression of ALDH1A1 mRNA CTD PMID:20959327 NCBI chr 1:238,222,689...238,264,381
Ensembl chr 1:238,222,521...238,264,330
JBrowse link
G Ankrd22 ankyrin repeat domain 22 increases expression ISO gadodiamide results in increased expression of ANKRD22 mRNA CTD PMID:20959327 NCBI chr 1:252,430,750...252,461,346
Ensembl chr 1:252,429,677...252,461,461
JBrowse link
G Atm ATM serine/threonine kinase increases expression ISO gadodiamide results in increased expression of ATM mRNA CTD PMID:20959327 NCBI chr 8:58,015,938...58,119,973
Ensembl chr 8:58,015,940...58,120,045
JBrowse link
G Atp8b1 ATPase phospholipid transporting 8B1 increases expression ISO gadodiamide results in increased expression of ATP8B1 mRNA CTD PMID:20959327 NCBI chr18:60,013,388...60,152,920
Ensembl chr18:60,013,382...60,095,354
JBrowse link
G Ccl2 C-C motif chemokine ligand 2 increases expression
increases secretion
ISO
EXP
gadodiamide results in increased expression of CCL2 mRNA
gadodiamide results in increased expression of CCL2 mRNA; gadodiamide results in increased expression of CCL2 protein
gadodiamide results in increased secretion of CCL2 protein
CTD PMID:20938346, PMID:20959327 NCBI chr10:69,412,065...69,413,863
Ensembl chr10:69,412,017...69,413,870
JBrowse link
G Ccl4 C-C motif chemokine ligand 4 increases expression EXP gadodiamide results in increased expression of CCL4 protein CTD PMID:20938346 NCBI chr10:70,870,926...70,886,357
Ensembl chr10:70,884,531...70,886,355
JBrowse link
G Ccl7 C-C motif chemokine ligand 7 increases expression EXP gadodiamide results in increased expression of CCL7 protein CTD PMID:20938346 NCBI chr10:69,423,083...69,424,933
Ensembl chr10:69,423,086...69,424,979
JBrowse link
G Cxcl10 C-X-C motif chemokine ligand 10 increases expression
increases secretion
ISO
EXP
gadodiamide results in increased expression of CXCL10 mRNA
gadodiamide results in increased expression of CXCL10 protein
gadodiamide results in increased secretion of CXCL10 protein
CTD PMID:20938346, PMID:20959327 NCBI chr14:17,210,733...17,212,930
Ensembl chr14:17,210,733...17,212,930
JBrowse link
G Cxcl11 C-X-C motif chemokine ligand 11 increases secretion
increases expression
ISO gadodiamide results in increased secretion of CXCL11 protein
gadodiamide results in increased expression of CXCL11 mRNA
CTD PMID:20959327 NCBI chr14:17,195,395...17,198,170
Ensembl chr14:17,195,014...17,198,291
JBrowse link
G Cxcl12 C-X-C motif chemokine ligand 12 increases expression ISO gadodiamide results in increased expression of CXCL12 mRNA CTD PMID:20959327 NCBI chr 4:149,261,044...149,273,891
Ensembl chr 4:149,261,044...149,273,891
JBrowse link
G Cxcl9 C-X-C motif chemokine ligand 9 increases expression ISO gadodiamide results in increased expression of CXCL9 mRNA CTD PMID:20959327 NCBI chr14:17,228,832...17,233,743
Ensembl chr14:17,228,856...17,234,712
JBrowse link
G Ido1 indoleamine 2,3-dioxygenase 1 increases expression ISO gadodiamide results in increased expression of IDO1 mRNA CTD PMID:20959327 NCBI chr16:72,216,326...72,228,098
Ensembl chr16:72,216,326...72,228,098
JBrowse link
G Ifi44l interferon-induced protein 44-like increases expression ISO gadodiamide results in increased expression of IFI44L mRNA CTD PMID:20959327 NCBI chr 2:256,948,722...256,979,573
Ensembl chr 2:256,964,860...256,978,668
JBrowse link
G Ifit3 interferon-induced protein with tetratricopeptide repeats 3 increases expression ISO gadodiamide results in increased expression of IFIT3 mRNA CTD PMID:20959327 NCBI chr 1:252,906,234...252,911,377
Ensembl chr 1:252,906,234...252,911,382
JBrowse link
G Ifng interferon gamma increases expression ISO gadodiamide results in increased expression of IFNG mRNA; gadodiamide results in increased expression of IFNG protein CTD PMID:19404939 NCBI chr 7:61,337,383...61,341,419
Ensembl chr 7:61,337,381...61,341,419
JBrowse link
G Il13 interleukin 13 increases expression ISO gadodiamide results in increased expression of IL13 mRNA; gadodiamide results in increased expression of IL13 protein CTD PMID:19404939 NCBI chr10:38,982,909...38,985,466
Ensembl chr10:38,982,909...38,985,466
JBrowse link
G Il1a interleukin 1 alpha increases expression EXP gadodiamide results in increased expression of IL1A protein CTD PMID:20938346 NCBI chr 3:121,824,712...121,836,122
Ensembl chr 3:121,825,412...121,836,086
JBrowse link
G Il4 interleukin 4 increases expression
affects expression
ISO gadodiamide results in increased expression of IL4 protein
gadodiamide affects the expression of IL4 mRNA
CTD PMID:19404939 NCBI chr10:38,963,979...38,969,531
Ensembl chr10:38,963,979...38,969,531
JBrowse link
G Il4i1 interleukin 4 induced 1 increases expression ISO gadodiamide results in increased expression of IL4I1 mRNA CTD PMID:20959327 NCBI chr 1:100,811,727...100,836,901
Ensembl chr 1:100,830,064...100,836,677
JBrowse link
G Il6 interleukin 6 affects expression
increases expression
ISO gadodiamide affects the expression of IL6 protein
gadodiamide results in increased expression of IL6 mRNA
CTD PMID:19404939 NCBI chr 4:3,043,231...3,047,807
Ensembl chr 4:3,043,231...3,047,807
JBrowse link
G Kitlg KIT ligand increases expression EXP gadodiamide results in increased expression of KITLG protein CTD PMID:20938346 NCBI chr 7:42,269,784...42,351,054
Ensembl chr 7:42,269,784...42,351,054
JBrowse link
G Mapk1 mitogen activated protein kinase 1 multiple interactions
increases phosphorylation
ISO 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [gadodiamide results in increased phosphorylation of MAPK1 protein]; U 0126 inhibits the reaction [gadodiamide results in increased phosphorylation of MAPK1 protein] CTD PMID:19561517 NCBI chr11:88,203,863...88,273,301
Ensembl chr11:88,211,599...88,273,254
JBrowse link
G Mapk3 mitogen activated protein kinase 3 multiple interactions
increases phosphorylation
ISO 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [gadodiamide results in increased phosphorylation of MAPK3 protein]; U 0126 inhibits the reaction [gadodiamide results in increased phosphorylation of MAPK3 protein] CTD PMID:19561517 NCBI chr 1:198,192,773...198,198,975
Ensembl chr 1:198,192,773...198,198,975
JBrowse link
G Mmp1 matrix metallopeptidase 1 multiple interactions
increases expression
ISO 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [gadodiamide results in increased expression of MMP1 protein]; U 0126 inhibits the reaction [gadodiamide results in increased expression of MMP1 protein]
gadodiamide results in increased expression of MMP1 mRNA; gadodiamide results in increased expression of MMP1 protein
CTD PMID:19561517 NCBI chr 8:5,703,206...5,723,593
Ensembl chr 8:5,703,206...5,723,591
JBrowse link
G Nos2 nitric oxide synthase 2 increases expression ISO gadodiamide results in increased expression of NOS2 protein CTD PMID:20959327 NCBI chr10:66,188,290...66,221,621
Ensembl chr10:66,189,786...66,313,190
JBrowse link
G Nxpe3 neurexophilin and PC-esterase domain family, member 3 increases expression ISO gadodiamide results in increased expression of NXPE3 mRNA CTD PMID:20959327 NCBI chr11:47,188,332...47,238,372
Ensembl chr11:47,188,495...47,238,372
JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit increases localization ISO gadodiamide results in increased localization of RELA protein CTD PMID:20959327 NCBI chr 1:220,992,770...221,003,249
Ensembl chr 1:220,992,770...221,003,249
JBrowse link
G RGD1306063 similar to HT021 increases expression ISO gadodiamide results in increased expression of C3ORF14 mRNA CTD PMID:20959327 NCBI chr15:12,869,217...12,889,144
Ensembl chr15:12,872,408...12,889,108
JBrowse link
G Rhoq ras homolog family member Q increases expression ISO gadodiamide results in increased expression of RHOQ mRNA CTD PMID:20959327 NCBI chr 6:10,533,151...10,568,582
Ensembl chr 6:10,533,151...10,568,581
JBrowse link
G Rit1 Ras-like without CAAX 1 increases expression ISO gadodiamide results in increased expression of RIT1 mRNA CTD PMID:20959327 NCBI chr 2:188,087,486...188,099,444
Ensembl chr 2:188,087,486...188,099,444
JBrowse link
G Rnf125 ring finger protein 125 increases expression ISO gadodiamide results in increased expression of RNF125 mRNA CTD PMID:20959327 NCBI chr18:15,193,226...15,225,454
Ensembl chr18:15,192,962...15,225,427
JBrowse link
G Rsad2 radical S-adenosyl methionine domain containing 2 increases expression ISO gadodiamide results in increased expression of RSAD2 mRNA CTD PMID:20959327 NCBI chr 6:45,655,947...45,669,083
Ensembl chr 6:45,655,954...45,669,148
JBrowse link
G Slc39a10 solute carrier family 39 member 10 increases expression ISO gadodiamide results in increased expression of SLC39A10 mRNA CTD PMID:20959327 NCBI chr 9:59,947,562...60,070,549
Ensembl chr 9:60,021,534...60,070,552
JBrowse link
G Spn sialophorin increases expression ISO gadodiamide results in increased expression of SPN mRNA CTD PMID:20959327 NCBI chr 1:198,572,999...198,585,664
Ensembl chr 1:198,572,999...198,577,226
JBrowse link
G Spp1 secreted phosphoprotein 1 increases expression EXP gadodiamide results in increased expression of SPP1 protein CTD PMID:20938346 NCBI chr14:6,673,686...6,679,965
Ensembl chr14:6,673,686...6,679,901
JBrowse link
G Tgfb1 transforming growth factor, beta 1 increases expression ISO
EXP
gadodiamide results in increased expression of TGFB1 mRNA; gadodiamide results in increased expression of TGFB1 protein CTD PMID:19404939, PMID:20938346 NCBI chr 1:82,480,875...82,497,196
Ensembl chr 1:82,480,195...82,497,199
JBrowse link
G Timp1 TIMP metallopeptidase inhibitor 1 increases expression
multiple interactions
ISO
EXP
gadodiamide results in increased expression of TIMP1 mRNA; gadodiamide results in increased expression of TIMP1 protein
2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one promotes the reaction [gadodiamide results in increased expression of TIMP1 protein]; U 0126 inhibits the reaction [gadodiamide results in increased expression of TIMP1 protein]
CTD PMID:19561517, PMID:20938346 NCBI chr  X:1,364,771...1,369,451
Ensembl chr  X:1,364,786...1,369,384
JBrowse link
G Ubd ubiquitin D increases expression ISO gadodiamide results in increased expression of UBD mRNA CTD PMID:20959327 NCBI chr20:1,876,175...1,878,126
Ensembl chr20:1,876,173...1,897,814
JBrowse link
G Vegfa vascular endothelial growth factor A increases expression ISO
EXP
gadodiamide results in increased expression of VEGFA mRNA; gadodiamide results in increased expression of VEGFA protein CTD PMID:19404939, PMID:20938346 NCBI chr 9:17,340,341...17,355,681
Ensembl chr 9:17,340,341...17,355,681
JBrowse link
G Wdr5 WD repeat domain 5 increases expression ISO gadodiamide results in increased expression of WDR5 mRNA CTD PMID:20959327 NCBI chr 3:6,061,892...6,080,724
Ensembl chr 3:6,061,940...6,080,680
JBrowse link
G Xiap X-linked inhibitor of apoptosis increases expression ISO gadodiamide results in increased expression of XIAP mRNA CTD PMID:20959327 NCBI chr  X:128,409,425...128,455,786
Ensembl chr  X:128,409,472...128,453,000
JBrowse link
G Zfp652 zinc finger protein 652 increases expression ISO gadodiamide results in increased expression of ZNF652 mRNA CTD PMID:20959327 NCBI chr10:83,556,809...83,572,014
Ensembl chr10:83,556,809...83,572,019
JBrowse link
lisinopril dihydrate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ace angiotensin I converting enzyme decreases activity ISO Lisinopril analog results in decreased activity of ACE protein CTD PMID:22200082 NCBI chr10:94,170,766...94,213,831
Ensembl chr10:94,170,766...94,187,822
JBrowse link
G Ace2 angiotensin I converting enzyme 2 increases expression
increases activity
EXP Lisinopril results in increased expression of ACE2 mRNA
Lisinopril results in increased activity of ACE2 protein
CTD PMID:15897343, PMID:16221218 NCBI chr  X:32,050,734...32,095,860
Ensembl chr  X:32,049,931...32,096,016
JBrowse link
G Ache acetylcholinesterase multiple interactions ISO
EXP
2,2-bis(4-glycidyloxyphenyl)propane inhibits the reaction [Lisinopril inhibits the reaction [Streptozocin results in increased activity of ACHE protein]]; Lisinopril inhibits the reaction [Streptozocin results in increased activity of ACHE protein]
Lisinopril inhibits the reaction [Sodium Fluoride results in decreased activity of ACHE protein]
CTD PMID:23060470, PMID:31710167 NCBI chr12:22,472,358...22,477,052
Ensembl chr12:22,472,358...22,478,753
JBrowse link
G Agt angiotensinogen decreases expression
multiple interactions
decreases secretion
increases secretion
affects response to substance
increases expression
ISO
EXP
Lisinopril results in decreased expression of AGT protein
[Lisinopril co-treated with Losartan] results in increased expression of AGT mRNA
Lisinopril results in decreased secretion of AGT protein
Lisinopril results in increased secretion of AGT protein alternative form
AGT gene alternative form affects the susceptibility to Lisinopril
Lisinopril results in increased expression of AGT mRNA
CTD PMID:8393685, PMID:8915971, PMID:15897343, PMID:16221218, PMID:16685205 NCBI chr19:57,321,594...57,333,460
Ensembl chr19:57,321,640...57,333,433
JBrowse link
G Bcl2 BCL2, apoptosis regulator decreases expression ISO Lisinopril results in decreased expression of BCL2 CTD PMID:10075388 NCBI chr13:26,605,426...26,769,374
Ensembl chr13:26,605,426...26,769,374
JBrowse link
G Cd2ap CD2-associated protein multiple interactions EXP Lisinopril inhibits the reaction [Doxorubicin results in increased expression of CD2AP protein] CTD PMID:16636307 NCBI chr 9:20,794,680...20,858,438
Ensembl chr 9:20,765,296...20,858,504
JBrowse link
G Edn1 endothelin 1 decreases secretion ISO Lisinopril results in decreased secretion of EDN1 protein CTD PMID:19079593 NCBI chr17:22,136,814...22,143,745
Ensembl chr17:22,137,324...22,143,324
JBrowse link
G Gh1 growth hormone 1 multiple interactions EXP [Lisinopril co-treated with GH1 protein] inhibits the reaction [Doxorubicin results in decreased expression of TIMP1 protein]; [Lisinopril co-treated with GH1 protein] inhibits the reaction [Doxorubicin results in increased expression of MMP2 protein]; [Lisinopril co-treated with GH1 protein] inhibits the reaction [Doxorubicin results in increased expression of NOS2 mRNA] CTD PMID:20051877 NCBI chr10:94,486,204...94,488,181
Ensembl chr10:94,486,205...94,488,180
JBrowse link
G Havcr1 hepatitis A virus cellular receptor 1 multiple interactions EXP Lisinopril inhibits the reaction [Doxorubicin results in increased expression of HAVCR1 mRNA]; Lisinopril inhibits the reaction [Doxorubicin results in increased expression of HAVCR1 protein] CTD PMID:19225054 NCBI chr10:31,813,819...31,860,934
Ensembl chr10:31,813,814...31,848,379
JBrowse link
G Hpse heparanase multiple interactions EXP [Spironolactone co-treated with Lisinopril] inhibits the reaction [Doxorubicin results in increased expression of HPSE protein]; Lisinopril inhibits the reaction [Doxorubicin results in increased expression of HPSE protein] CTD PMID:19429930 NCBI chr14:10,534,358...10,576,686
Ensembl chr14:10,534,423...10,575,224
JBrowse link
G Igfbp1 insulin-like growth factor binding protein 1 increases expression ISO Lisinopril results in increased expression of IGFBP1 protein CTD PMID:9663927 NCBI chr14:87,448,716...87,453,783
Ensembl chr14:87,448,692...87,453,785
JBrowse link
G Mmp2 matrix metallopeptidase 2 multiple interactions EXP [Lisinopril co-treated with GH1 protein] inhibits the reaction [Doxorubicin results in increased expression of MMP2 protein]; Lisinopril inhibits the reaction [Doxorubicin results in increased expression of MMP2 protein] CTD PMID:20051877 NCBI chr19:15,542,771...15,570,589
Ensembl chr19:15,542,765...15,570,611
JBrowse link
G Mpo myeloperoxidase multiple interactions ISO 2,2-bis(4-glycidyloxyphenyl)propane inhibits the reaction [Lisinopril inhibits the reaction [Streptozocin results in increased activity of MPO protein]]; Lisinopril inhibits the reaction [Streptozocin results in increased activity of MPO protein] CTD PMID:23060470 NCBI chr10:75,087,892...75,098,260
Ensembl chr10:75,087,892...75,098,260
JBrowse link
G Nos2 nitric oxide synthase 2 multiple interactions EXP [Lisinopril co-treated with GH1 protein] inhibits the reaction [Doxorubicin results in increased expression of NOS2 mRNA]; Lisinopril inhibits the reaction [Doxorubicin results in increased expression of NOS2 mRNA] CTD PMID:20051877 NCBI chr10:66,188,290...66,221,621
Ensembl chr10:66,189,786...66,313,190
JBrowse link
G Nphs1 NPHS1 adhesion molecule, nephrin multiple interactions EXP Lisinopril inhibits the reaction [Doxorubicin results in decreased phosphorylation of NPHS1 protein]; Lisinopril inhibits the reaction [Doxorubicin results in increased expression of NPHS1 protein] CTD PMID:16636307, PMID:19293598 NCBI chr 1:88,922,346...88,950,560
Ensembl chr 1:88,922,433...88,950,559
JBrowse link
G Nphs2 NPHS2 stomatin family member, podocin multiple interactions EXP Lisinopril affects the reaction [Doxorubicin results in increased expression of NPHS2 mRNA]; Lisinopril affects the reaction [Doxorubicin results in increased expression of NPHS2 protein] CTD PMID:16636307 NCBI chr13:73,929,136...73,941,522
Ensembl chr13:73,929,136...73,941,522
JBrowse link
G Nppa natriuretic peptide A decreases expression ISO Lisinopril results in decreased expression of NPPA protein CTD PMID:8393685 NCBI chr 5:164,808,407...164,809,716
Ensembl chr 5:164,808,323...164,809,705
JBrowse link
G Ren renin increases expression
multiple interactions
ISO
EXP
Lisinopril results in increased expression of REN protein
[Lisinopril co-treated with Losartan] results in increased expression of REN mRNA
Lisinopril results in increased expression of REN mRNA
CTD PMID:2550029, PMID:8915971, PMID:16221218 NCBI chr13:50,502,724...50,513,953
Ensembl chr13:50,502,724...50,514,151
JBrowse link
G Timp1 TIMP metallopeptidase inhibitor 1 multiple interactions EXP [Lisinopril co-treated with GH1 protein] inhibits the reaction [Doxorubicin results in decreased expression of TIMP1 protein]; Lisinopril inhibits the reaction [Doxorubicin results in decreased expression of TIMP1 protein] CTD PMID:20051877 NCBI chr  X:1,364,771...1,369,451
Ensembl chr  X:1,364,786...1,369,384
JBrowse link
G Vegfa vascular endothelial growth factor A multiple interactions EXP Lisinopril inhibits the reaction [Doxorubicin results in decreased expression of VEGFA protein] CTD PMID:19293598 NCBI chr 9:17,340,341...17,355,681
Ensembl chr 9:17,340,341...17,355,681
JBrowse link
potassium citrate monohydrate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Nefh neurofilament heavy affects expression EXP Potassium Citrate affects the expression of NEFH mRNA CTD PMID:22954530 NCBI chr14:85,181,572...85,191,557
Ensembl chr14:85,181,572...85,191,557
JBrowse link
royal jelly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bcl2 BCL2, apoptosis regulator multiple interactions ISO royal jelly inhibits the reaction [Nicotine results in decreased expression of BCL2 mRNA] CTD PMID:30896085 NCBI chr13:26,605,426...26,769,374
Ensembl chr13:26,605,426...26,769,374
JBrowse link
G Casp3 caspase 3 multiple interactions ISO royal jelly inhibits the reaction [Nicotine results in increased expression of CASP3 mRNA] CTD PMID:30896085 NCBI chr16:48,845,011...48,863,249
Ensembl chr16:48,845,012...48,863,204
JBrowse link
G Cat catalase multiple interactions EXP
ISO
royal jelly inhibits the reaction [Cisplatin results in decreased activity of CAT protein]
royal jelly inhibits the reaction [Nicotine results in decreased activity of CAT protein]
CTD PMID:20369241, PMID:30896085 NCBI chr 3:93,379,872...93,412,058
Ensembl chr 3:93,379,874...93,412,058
JBrowse link
G Esr1 estrogen receptor 1 multiple interactions
increases activity
affects binding
ISO Estradiol inhibits the reaction [royal jelly binds to ESR1 protein]; royal jelly binds to and results in increased activity of ESR1 protein; royal jelly inhibits the reaction [Estradiol binds to ESR1 protein]
royal jelly results in increased activity of ESR1 protein
CTD PMID:15946813, PMID:17287592 NCBI chr 1:41,192,029...41,594,799
Ensembl chr 1:41,192,824...41,594,796
JBrowse link
G Esr2 estrogen receptor 2 multiple interactions
affects binding
ISO Estradiol inhibits the reaction [royal jelly binds to ESR2 protein]; royal jelly binds to and results in increased activity of ESR2 protein; royal jelly inhibits the reaction [Estradiol binds to ESR2 protein] CTD PMID:15946813, PMID:17287592 NCBI chr 6:99,163,953...99,214,711
Ensembl chr 6:99,164,357...99,214,251
JBrowse link
G Pcna proliferating cell nuclear antigen multiple interactions ISO royal jelly inhibits the reaction [Nicotine results in decreased expression of PCNA protein] CTD PMID:30896085 NCBI chr 3:124,880,698...124,884,570
Ensembl chr 3:124,880,698...124,884,570
JBrowse link
G Tff1 trefoil factor 1 increases expression ISO royal jelly results in increased expression of TFF1 mRNA CTD PMID:15946813 NCBI chr20:9,892,124...9,895,984
Ensembl chr20:9,892,124...9,895,984
JBrowse link
G Tp53 tumor protein p53 multiple interactions ISO royal jelly inhibits the reaction [Nicotine results in increased expression of TRP53 mRNA] CTD PMID:30896085 NCBI chr10:56,186,299...56,198,449
Ensembl chr10:56,187,020...56,198,449
JBrowse link
G Vegfa vascular endothelial growth factor A increases expression ISO
EXP
royal jelly results in increased expression of VEGFA mRNA CTD PMID:15946813, PMID:17287592 NCBI chr 9:17,340,341...17,355,681
Ensembl chr 9:17,340,341...17,355,681
JBrowse link
sodium acetate trihydrate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ada adenosine deaminase multiple interactions EXP Sodium Acetate inhibits the reaction [Nicotine results in increased activity of ADA protein] CTD PMID:31857090 NCBI chr 3:160,115,840...160,139,947
Ensembl chr 3:160,115,842...160,139,947
JBrowse link
G Apob apolipoprotein B multiple interactions ISO [Sodium Acetate co-treated with acetic anhydride] results in increased acetylation of APOB protein CTD PMID:11304478 NCBI chr 6:33,176,826...33,216,381
Ensembl chr 6:33,176,778...33,224,997
JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 multiple interactions ISO Sodium Acetate promotes the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A1 mRNA]
Sodium Acetate promotes the reaction [biochanin A results in increased expression of CYP1A1 mRNA]; Sodium Acetate promotes the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A1 mRNA]
CTD PMID:31621310 NCBI chr 8:62,472,087...62,478,122
Ensembl chr 8:62,472,095...62,478,147
JBrowse link
G Cyp1b1 cytochrome P450, family 1, subfamily b, polypeptide 1 multiple interactions ISO Sodium Acetate promotes the reaction [biochanin A results in increased expression of CYP1B1 mRNA]; Sodium Acetate promotes the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1B1 mRNA] CTD PMID:31621310 NCBI chr 6:2,308,179...2,316,739
Ensembl chr 6:2,307,808...2,316,722
JBrowse link
G Ggt1 gamma-glutamyltransferase 1 multiple interactions EXP Sodium Acetate inhibits the reaction [Nicotine results in increased activity of GGT1 protein] CTD PMID:31857090 NCBI chr20:14,019,723...14,045,781
Ensembl chr20:14,019,723...14,025,068
JBrowse link
G Il2 interleukin 2 multiple interactions ISO Sodium Acetate inhibits the reaction [[Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased activity of IL2 protein] CTD PMID:17615583 NCBI chr 2:123,847,150...123,851,854
Ensembl chr 2:123,847,150...123,851,854
JBrowse link
G Kpnb1 karyopherin subunit beta 1 multiple interactions ISO Sodium Acetate inhibits the reaction [[Ionomycin co-treated with Tetradecanoylphorbol Acetate] promotes the reaction [NFATC2 protein binds to KPNB1 protein]] CTD PMID:17615583 NCBI chr10:85,096,517...85,124,641
Ensembl chr10:85,093,841...85,124,644
JBrowse link
G Nfatc2 nuclear factor of activated T-cells 2 multiple interactions ISO Sodium Acetate inhibits the reaction [[Ionomycin co-treated with Tetradecanoylphorbol Acetate] affects the localization of NFATC2 protein]; Sodium Acetate inhibits the reaction [[Ionomycin co-treated with Tetradecanoylphorbol Acetate] promotes the reaction [NFATC2 protein binds to KPNB1 protein]]; Sodium Acetate inhibits the reaction [[Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased activity of NFATC2 protein] CTD PMID:17615583 NCBI chr 3:165,241,750...165,374,644
Ensembl chr 3:165,245,238...165,360,292
JBrowse link
G Ugt1a1 UDP glucuronosyltransferase family 1 member A1 multiple interactions ISO Sodium Acetate promotes the reaction [Tetrachlorodibenzodioxin results in increased expression of UGT1A1 mRNA] CTD PMID:31621310 NCBI chr 9:95,295,701...95,302,822
Ensembl chr 9:95,161,157...95,302,822
JBrowse link
G Xdh xanthine dehydrogenase multiple interactions EXP Sodium Acetate inhibits the reaction [Nicotine results in increased activity of XDH protein] CTD PMID:31857090 NCBI chr 6:25,149,570...25,211,273
Ensembl chr 6:25,149,235...25,211,494
JBrowse link
tacrolimus hydrate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G A2m alpha-2-macroglobulin increases expression EXP Tacrolimus results in increased expression of A2M mRNA CTD PMID:21865292 NCBI chr 4:154,309,426...154,359,138
Ensembl chr 4:154,309,426...154,359,137
JBrowse link
G Abca1 ATP binding cassette subfamily A member 1 multiple interactions
increases expression
ISO
EXP
[Sirolimus co-treated with Tacrolimus] results in increased expression of ABCA1 protein
Tacrolimus results in increased expression of ABCA1 mRNA
CTD PMID:17016853, PMID:21865292 NCBI chr 5:69,857,717...69,983,042
Ensembl chr 5:69,857,771...69,983,015
JBrowse link
G Abcb11 ATP binding cassette subfamily B member 11 decreases activity ISO Tacrolimus results in decreased activity of ABCB11 protein CTD PMID:23956101 NCBI chr 3:55,480,024...55,587,946
Ensembl chr 3:55,480,024...55,587,946
JBrowse link
G Abcb1a ATP binding cassette subfamily B member 1A affects export
decreases activity
multiple interactions
increases response to substance
increases export
affects response to substance
ISO ABCB1 protein affects the export of Tacrolimus
Tacrolimus results in decreased activity of ABCB1 protein
[Tacrolimus binds to ABCB1 protein] inhibits the reaction [azidoprazosin binds to ABCB1 protein]; [Tacrolimus results in decreased activity of ABCB1 protein] which results in decreased export of Dexamethasone; Verapamil affects the reaction [ABCB1 protein results in increased export of Tacrolimus]
ABCB1 gene SNP results in increased susceptibility to Tacrolimus
ABCB1 protein affects the susceptibility to Tacrolimus
CTD PMID:1381629, PMID:11920757, PMID:12352921, PMID:15919446, PMID:15964336, PMID:20080907 NCBI chr 4:22,339,829...22,517,642
Ensembl chr 4:22,133,521...22,425,515
JBrowse link
G Acaa1b acetyl-Coenzyme A acyltransferase 1B decreases expression ISO Tacrolimus results in decreased expression of ACAA1B mRNA CTD PMID:25270620 NCBI chr 8:127,836,235...127,845,296 JBrowse link
G Acadl acyl-CoA dehydrogenase, long chain decreases expression ISO Tacrolimus results in decreased expression of ACADL mRNA CTD PMID:25270620 NCBI chr 9:73,833,368...73,871,857
Ensembl chr 9:73,833,388...73,871,888
JBrowse link
G Ace2 angiotensin I converting enzyme 2 decreases expression EXP Tacrolimus results in decreased expression of ACE2 mRNA CTD PMID:21865292 NCBI chr  X:32,050,734...32,095,860
Ensembl chr  X:32,049,931...32,096,016
JBrowse link
G Acp5 acid phosphatase 5, tartrate resistant multiple interactions ISO Tacrolimus inhibits the reaction [TNFSF11 protein results in increased expression of ACP5 protein] CTD PMID:15207740 NCBI chr 8:23,142,733...23,149,067
Ensembl chr 8:23,142,734...23,148,396
JBrowse link
G Acta2 actin alpha 2, smooth muscle increases expression ISO Tacrolimus results in increased expression of ACTA2 protein CTD PMID:29362864 NCBI chr 1:252,537,614...252,550,394
Ensembl chr 1:252,537,615...252,550,394
JBrowse link
G Acvr1b activin A receptor type 1B multiple interactions ISO [Tacrolimus inhibits the reaction [FKBP1A protein binds to ACVR1B protein]] which results in decreased ubiquitination of ACVR1B protein; Tacrolimus inhibits the reaction [FKBP1A protein binds to and results in decreased activity of ACVR1B protein]; Tacrolimus inhibits the reaction [FKBP1A protein promotes the reaction [SMURF1 protein binds to SMAD7 protein binds to ACVR1B protein]] CTD PMID:16720724 NCBI chr 7:142,817,174...142,858,365
Ensembl chr 7:142,817,157...142,860,572
JBrowse link
G Adamts1 ADAM metallopeptidase with thrombospondin type 1 motif, 1 increases expression EXP Tacrolimus results in increased expression of ADAMTS1 mRNA CTD PMID:21865292 NCBI chr11:25,342,119...25,350,938
Ensembl chr11:25,342,126...25,350,974
JBrowse link
G Adamts2 ADAM metallopeptidase with thrombospondin type 1 motif, 2 increases expression ISO Tacrolimus results in increased expression of ADAMTS2 mRNA CTD PMID:29362864 NCBI chr10:36,098,051...36,304,416
Ensembl chr10:36,098,051...36,304,409
JBrowse link
G Adcy9 adenylate cyclase 9 multiple interactions ISO Tacrolimus inhibits the reaction [Calcium inhibits the reaction [Miconazole results in increased activity of ADCY9 protein]] CTD PMID:30607468 NCBI chr10:11,392,698...11,515,406
Ensembl chr10:11,392,625...11,512,600
JBrowse link
G Adra1d adrenoceptor alpha 1D increases expression EXP Tacrolimus results in increased expression of ADRA1D mRNA CTD PMID:21865292 NCBI chr 3:124,129,558...124,145,566
Ensembl chr 3:124,129,558...124,145,566
JBrowse link
G Aif1 allograft inflammatory factor 1 increases expression ISO Tacrolimus results in increased expression of AIF1 mRNA CTD PMID:29362864 NCBI chr20:5,161,350...5,167,176
Ensembl chr20:5,161,333...5,166,448
JBrowse link
G Aldh1a1 aldehyde dehydrogenase 1 family, member A1 decreases expression ISO Tacrolimus results in decreased expression of ALDH1A1 mRNA CTD PMID:25270620 NCBI chr 1:238,222,689...238,264,381
Ensembl chr 1:238,222,521...238,264,330
JBrowse link
G Aldh2 aldehyde dehydrogenase 2 family member decreases expression ISO Tacrolimus results in decreased expression of ALDH2 mRNA CTD PMID:25270620 NCBI chr12:40,466,418...40,498,813
Ensembl chr12:40,466,495...40,498,752
JBrowse link
G Aldh9a1 aldehyde dehydrogenase 9 family, member A1 decreases expression ISO Tacrolimus results in decreased expression of ALDH9A1 mRNA CTD PMID:25270620 NCBI chr13:85,580,828...85,597,497
Ensembl chr13:85,580,828...85,597,493
JBrowse link
G Alg3 ALG3, alpha-1,3- mannosyltransferase decreases expression ISO Tacrolimus results in decreased expression of ALG3 mRNA CTD PMID:25270620 NCBI chr11:83,985,484...83,991,706
Ensembl chr11:83,986,230...83,991,706
JBrowse link
G Angptl6 angiopoietin-like 6 increases expression EXP Tacrolimus results in increased expression of ANGPTL6 mRNA CTD PMID:21865292 NCBI chr 8:21,895,523...21,902,002
Ensembl chr 8:21,895,524...21,901,829
JBrowse link
G Ankrd1 ankyrin repeat domain 1 increases expression ISO Tacrolimus results in increased expression of ANKRD1 mRNA CTD PMID:29362864 NCBI chr 1:254,726,985...254,745,673
Ensembl chr 1:254,726,969...254,735,548
JBrowse link
G Ankrd34a ankyrin repeat domain 34A decreases expression ISO Tacrolimus results in decreased expression of ANKRD34A mRNA CTD PMID:25270620 NCBI chr 2:198,720,277...198,725,155
Ensembl chr 2:198,721,724...198,725,154
JBrowse link
G Anos1 anosmin 1 increases expression ISO Tacrolimus results in increased expression of WFDC17 mRNA CTD PMID:29362864 Ensembl chr10:70,999,780...71,000,627 JBrowse link
G Anpep alanyl aminopeptidase, membrane increases secretion EXP Tacrolimus results in increased secretion of ANPEP protein CTD PMID:7514309 NCBI chr 1:141,561,364...141,604,249
Ensembl chr 1:141,561,334...141,604,273
JBrowse link
G Anxa1 annexin A1 increases expression EXP Tacrolimus results in increased expression of ANXA1 CTD PMID:20484890 NCBI chr 1:237,893,983...237,910,002
Ensembl chr 1:237,893,966...237,910,012
JBrowse link
G Aoc1 amine oxidase, copper containing 1 increases expression ISO Tacrolimus results in increased expression of AOC1 mRNA CTD PMID:29362864 NCBI chr 4:78,496,043...78,515,582
Ensembl chr 4:78,496,043...78,515,584
JBrowse link
G Areg amphiregulin increases expression EXP Tacrolimus results in increased expression of AREG mRNA CTD PMID:21865292 NCBI chr14:18,521,921...18,531,179
Ensembl chr14:18,521,930...18,531,179
JBrowse link
G Arfrp1 ADP-ribosylation factor related protein 1 increases expression ISO Tacrolimus results in increased expression of ARFRP1 mRNA CTD PMID:25270620 NCBI chr 3:176,857,667...176,865,105
Ensembl chr 3:176,859,151...176,865,103
JBrowse link
G Arhgap45 Rho GTPase activating protein 45 increases expression ISO Tacrolimus results in increased expression of ARHGAP45 mRNA CTD PMID:21621594 NCBI chr 7:12,541,032...12,741,314
Ensembl chr 7:12,541,061...12,741,296
JBrowse link
G Arhgef11 Rho guanine nucleotide exchange factor 11 increases expression ISO Tacrolimus results in increased expression of ARHGEF11 mRNA CTD PMID:29380240 NCBI chr 2:186,979,850...187,102,523
Ensembl chr 2:186,980,793...187,101,768
JBrowse link
G Arpc5 actin related protein 2/3 complex, subunit 5 increases expression ISO Tacrolimus results in increased expression of ARPC5 mRNA CTD PMID:29380240 NCBI chr13:70,174,970...70,183,879
Ensembl chr13:70,174,936...70,183,879
JBrowse link
G Arv1 ARV1 homolog, fatty acid homeostasis modulator increases expression ISO Tacrolimus results in increased expression of ARV1 mRNA CTD PMID:25270620 NCBI chr19:57,484,720...57,496,539
Ensembl chr19:57,484,634...57,496,695
JBrowse link
G Asxl3 ASXL transcriptional regulator 3 decreases expression ISO Tacrolimus results in decreased expression of ASXL3 mRNA CTD PMID:29362864 NCBI chr18:13,322,148...13,496,230
Ensembl chr18:13,386,133...13,491,735
JBrowse link
G Atf3 activating transcription factor 3 increases expression ISO Tacrolimus results in increased expression of ATF3 mRNA CTD PMID:23958496 NCBI chr13:109,817,892...109,849,632
Ensembl chr13:109,817,728...109,849,632
JBrowse link
G Atf4 activating transcription factor 4 increases expression ISO Tacrolimus results in increased expression of ATF4 mRNA CTD PMID:23958496 NCBI chr 7:121,480,723...121,482,781
Ensembl chr 7:121,480,723...121,482,772
JBrowse link
G Atf6 activating transcription factor 6 increases expression ISO Tacrolimus results in increased expression of ATF6 mRNA CTD PMID:23958496 NCBI chr13:89,053,457...89,242,531
Ensembl chr13:89,055,983...89,242,443
JBrowse link
G Atp1b1 ATPase Na+/K+ transporting subunit beta 1 decreases expression ISO Tacrolimus results in decreased expression of ATP1B1 mRNA CTD PMID:25270620 NCBI chr13:82,737,161...82,757,681
Ensembl chr13:82,737,159...82,758,004
JBrowse link
G Atp1b3 ATPase Na+/K+ transporting subunit beta 3 decreases expression ISO Tacrolimus results in decreased expression of ATP1B3 mRNA CTD PMID:25270620 NCBI chr 8:104,190,032...104,221,342
Ensembl chr 8:104,190,032...104,221,342
JBrowse link
G Atp2a2 ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 2 increases expression ISO Tacrolimus results in increased expression of ATP2A2 mRNA CTD PMID:25270620 NCBI chr12:39,553,903...39,603,326
Ensembl chr12:39,553,903...39,603,326
JBrowse link
G B2m beta-2 microglobulin increases expression ISO Tacrolimus results in increased expression of B2M mRNA CTD PMID:29362864 NCBI chr 3:114,087,287...114,093,311
Ensembl chr 3:114,087,287...114,093,309
JBrowse link
G Bad BCL2-associated agonist of cell death multiple interactions EXP
ISO
Tacrolimus inhibits the reaction [Ammonium Chloride results in decreased phosphorylation of BAD protein]
Tacrolimus inhibits the reaction [Rotenone results in decreased phosphorylation of BAD protein]
CTD PMID:15036616, PMID:15280438 NCBI chr 1:222,198,516...222,207,459
Ensembl chr 1:222,198,534...222,207,453
JBrowse link
G Batf3 basic leucine zipper ATF-like transcription factor 3 increases expression ISO Tacrolimus results in increased expression of BATF3 mRNA CTD PMID:29362864 NCBI chr13:109,713,376...109,726,438
Ensembl chr13:109,713,489...109,724,863
JBrowse link
G Bax BCL2 associated X, apoptosis regulator multiple interactions ISO
EXP
Tacrolimus inhibits the reaction [[Lipopolysaccharides co-treated with IFNG protein] results in increased expression of BAX protein]
[Tacrolimus co-treated with 3-nitropropionic acid] affects the localization of BAX protein
CTD PMID:10205001, PMID:15571979 NCBI chr 1:101,451,801...101,457,207
Ensembl chr 1:101,451,802...101,457,207
JBrowse link
G Bcl2 BCL2, apoptosis regulator multiple interactions
increases expression
ISO
EXP
Tacrolimus inhibits the reaction [[Lipopolysaccharides co-treated with IFNG protein] results in decreased expression of BCL2 protein]
[Tacrolimus co-treated with 3-nitropropionic acid] affects the localization of BCL2 protein
Tacrolimus results in increased expression of BCL2 protein
CTD PMID:10205001, PMID:15571979 NCBI chr13:26,605,426...26,769,374
Ensembl chr13:26,605,426...26,769,374
JBrowse link
G Bcl2l1 Bcl2-like 1 multiple interactions ISO Tacrolimus inhibits the reaction [Superantigens results in increased expression of BCL2L1 protein] CTD PMID:10532544 NCBI chr 3:148,259,594...148,314,191
Ensembl chr 3:148,259,596...148,313,810
JBrowse link
G Bcl3 BCL3, transcription coactivator increases expression ISO Tacrolimus results in increased expression of BCL3 mRNA CTD PMID:23958496 NCBI chr 1:80,730,758...80,745,273
Ensembl chr 1:80,730,499...80,744,831
JBrowse link
G Bdnf brain-derived neurotrophic factor multiple interactions EXP Tacrolimus inhibits the reaction [decamethrin results in increased expression of BDNF exon]; Tacrolimus promotes the reaction [U 0126 inhibits the reaction [decamethrin results in increased expression of BDNF exon]]; U 0126 promotes the reaction [Tacrolimus inhibits the reaction [decamethrin results in increased expression of BDNF exon]] CTD PMID:22079160 NCBI chr 3:100,768,637...100,819,216
Ensembl chr 3:100,768,637...100,819,210
JBrowse link
G Birc3 baculoviral IAP repeat-containing 3 increases expression EXP Tacrolimus results in increased expression of BIRC3 mRNA CTD PMID:21865292 NCBI chr 8:6,048,590...6,076,828
Ensembl chr 8:6,048,969...6,076,598
JBrowse link
G Birc5 baculoviral IAP repeat-containing 5 decreases expression ISO Tacrolimus results in decreased expression of BIRC5 mRNA CTD PMID:16574167 NCBI chr10:106,856,097...106,864,419
Ensembl chr10:106,856,097...106,864,413
JBrowse link
G Bmp7 bone morphogenetic protein 7 multiple interactions
decreases expression
EXP Ramipril inhibits the reaction [Tacrolimus results in decreased expression of BMP7 protein]; valsartan inhibits the reaction [Tacrolimus results in decreased expression of BMP7 protein] CTD PMID:17703430 NCBI chr 3:170,879,972...170,955,820
Ensembl chr 3:170,879,973...170,955,399
JBrowse link
G Btg2 BTG anti-proliferation factor 2 increases expression EXP Tacrolimus results in increased expression of BTG2 mRNA CTD PMID:21865292 NCBI chr13:50,913,185...50,916,944
Ensembl chr13:50,913,180...50,916,982
JBrowse link
G Btnl9 butyrophilin-like 9 decreases expression ISO Tacrolimus results in decreased expression of BTNL9 mRNA CTD PMID:29362864 NCBI chr10:34,424,830...34,443,749
Ensembl chr10:34,425,069...34,439,470
JBrowse link
G C1qa complement C1q A chain increases expression ISO Tacrolimus results in increased expression of C1QA mRNA CTD PMID:29362864 NCBI chr 5:155,261,254...155,264,101
Ensembl chr 5:155,261,250...155,264,143
JBrowse link
G C1qb complement C1q B chain increases expression ISO Tacrolimus results in increased expression of C1QB mRNA CTD PMID:29362864 NCBI chr 5:155,246,444...155,251,995
Ensembl chr 5:155,246,447...155,252,003
JBrowse link
G C1qc complement C1q C chain increases expression ISO Tacrolimus results in increased expression of C1QC mRNA CTD PMID:29362864 NCBI chr 5:155,255,013...155,258,631
Ensembl chr 5:155,255,005...155,258,392
JBrowse link
G C2 complement C2 increases expression EXP Tacrolimus results in increased expression of C2 mRNA CTD PMID:21865292 NCBI chr20:4,542,340...4,561,152
Ensembl chr20:4,542,340...4,561,152
JBrowse link
G C3 complement C3 increases expression EXP
ISO
Tacrolimus results in increased expression of C3 mRNA CTD PMID:21865292, PMID:29362864 NCBI chr 9:9,721,137...9,747,084
Ensembl chr 9:9,721,105...9,747,167
JBrowse link
G C4b complement C4B (Chido blood group) increases expression EXP Tacrolimus results in increased expression of C4B mRNA CTD PMID:21865292 NCBI chr20:4,302,344...4,316,752
Ensembl chr20:4,302,344...4,316,715
JBrowse link
G Calb1 calbindin 1 decreases expression EXP Tacrolimus results in decreased expression of CALB1 mRNA; Tacrolimus results in decreased expression of CALB1 protein CTD PMID:14978156, PMID:21865292 NCBI chr 5:29,538,380...29,562,774
Ensembl chr 5:29,538,380...29,562,773
JBrowse link
G Calcr calcitonin receptor multiple interactions ISO Tacrolimus inhibits the reaction [TNFSF11 protein results in increased expression of CALCR mRNA] CTD PMID:21869564 NCBI chr 4:28,627,439...28,702,559
Ensembl chr 4:28,627,442...28,702,559
JBrowse link
G Calr calreticulin increases expression ISO Tacrolimus results in increased expression of CALR mRNA CTD PMID:25270620 NCBI chr19:25,956,771...25,961,666
Ensembl chr19:25,956,771...25,961,666
JBrowse link
G Camk1d calcium/calmodulin-dependent protein kinase ID increases expression ISO Tacrolimus results in increased expression of CAMK1D mRNA CTD PMID:23958496 NCBI chr17:76,532,611...76,938,956
Ensembl chr17:76,532,611...76,938,956
JBrowse link
G Capg capping actin protein, gelsolin like increases expression EXP Tacrolimus results in increased expression of CAPG mRNA CTD PMID:21865292 NCBI chr 4:100,395,693...100,419,447
Ensembl chr 4:100,407,658...100,419,446
JBrowse link
G Casp3 caspase 3 multiple interactions
increases activity
ISO
EXP
Tacrolimus inhibits the reaction [FAS protein results in increased activity of CASP3 protein]; Tacrolimus inhibits the reaction [Thapsigargin results in increased activity of CASP3 protein]
Tacrolimus results in increased activity of CASP3 protein
MK0626 inhibits the reaction [Tacrolimus results in increased activity of CASP3 protein]; NGF protein inhibits the reaction [Tacrolimus results in increased activity of CASP3 protein]; Tacrolimus inhibits the reaction [3-nitropropionic acid results in increased activity of CASP3 protein]; Tacrolimus inhibits the reaction [[Lithium co-treated with Pilocarpine] results in increased activity of CASP3 protein]; Tacrolimus inhibits the reaction [Hydrogen Peroxide results in increased activity of CASP3 protein]; Tacrolimus inhibits the reaction [Oxygen deficiency results in increased activity of CASP3 protein]
Tacrolimus inhibits the reaction [[Lipopolysaccharides co-treated with IFNG protein] results in increased activity of CASP3 protein]; Tacrolimus inhibits the reaction [S-Nitrosoglutathione results in increased activity of CASP3 protein]
CTD PMID:10205001, PMID:12642403, PMID:12871656, PMID:12892836, PMID:15207740, PMID:15548389, PMID:15571979, PMID:17166486, PMID:17385075, PMID:20149694, PMID:24959755 NCBI chr16:48,845,011...48,863,249
Ensembl chr16:48,845,012...48,863,204
JBrowse link
G Casp8 caspase 8 multiple interactions ISO Tacrolimus inhibits the reaction [FAS protein results in increased activity of CASP8 protein] CTD PMID:15548389 NCBI chr 9:65,614,142...65,662,624
Ensembl chr 9:65,614,142...65,662,106
JBrowse link
G Casp9 caspase 9 multiple interactions ISO Tacrolimus inhibits the reaction [FAS protein results in increased activity of CASP9 protein] CTD PMID:15548389 NCBI chr 5:160,356,211...160,373,774
Ensembl chr 5:160,355,833...160,373,778
JBrowse link
G Cat catalase increases expression
decreases response to substance
EXP
ISO
Tacrolimus results in increased expression of CAT protein
CAT protein results in decreased susceptibility to Tacrolimus
CTD PMID:14675044, PMID:18766458 NCBI chr 3:93,379,872...93,412,058
Ensembl chr 3:93,379,874...93,412,058
JBrowse link
G Cbll1 Cbl proto-oncogene like 1 increases expression ISO Tacrolimus results in increased expression of CBLL1 mRNA CTD PMID:21621594 NCBI chr 6:50,772,718...50,786,861
Ensembl chr 6:50,772,829...50,786,967
JBrowse link
G Ccdc88b coiled-coil domain containing 88B increases expression ISO Tacrolimus results in increased expression of CCDC88B mRNA CTD PMID:29362864 NCBI chr 1:222,102,436...222,118,485
Ensembl chr 1:222,102,437...222,118,459
JBrowse link
G Ccl11 C-C motif chemokine ligand 11 decreases expression ISO Tacrolimus results in decreased expression of CCL11 mRNA CTD PMID:15948978 NCBI chr10:69,434,965...69,439,566
Ensembl chr10:69,434,941...69,439,575
JBrowse link
G Ccl17 C-C motif chemokine ligand 17 increases expression ISO Tacrolimus results in increased expression of CCL17 mRNA CTD PMID:29362864 NCBI chr19:10,619,220...10,620,671
Ensembl chr19:10,619,220...10,620,671
JBrowse link
G Ccl2 C-C motif chemokine ligand 2 multiple interactions
increases expression
EXP
ISO
pyrrolidine dithiocarbamic acid inhibits the reaction [Tacrolimus results in increased expression of CCL2 mRNA]
7-oxozeanol inhibits the reaction [Tacrolimus results in increased expression of CCL2 mRNA]; 7-oxozeanol inhibits the reaction [Tacrolimus results in increased expression of CCL2 protein]; alpha-cyano-(3,4-dihydroxy)-N-benzylcinnamide inhibits the reaction [Tacrolimus results in increased expression of CCL2 mRNA]; alpha-cyano-(3,4-dihydroxy)-N-benzylcinnamide inhibits the reaction [Tacrolimus results in increased expression of CCL2 protein]; ethyl 6-(N-(2-chloro-4-fluorophenyl)sulfamoyl)cyclohex-1-ene-1-carboxylate inhibits the reaction [Tacrolimus results in increased expression of CCL2 mRNA]; parthenolide inhibits the reaction [Tacrolimus results in increased expression of CCL2 mRNA]; pyrazolanthrone inhibits the reaction [Tacrolimus results in increased expression of CCL2 mRNA]; pyrazolanthrone inhibits the reaction [Tacrolimus results in increased expression of CCL2 protein]; salubrinal inhibits the reaction [Tacrolimus results in increased expression of CCL2 mRNA]; sulforafan inhibits the reaction [Tacrolimus results in increased expression of CCL2 mRNA]
CTD PMID:12472797, PMID:23958496, PMID:29362864 NCBI chr10:69,412,065...69,413,863
Ensembl chr10:69,412,017...69,413,870
JBrowse link
G Ccl20 C-C motif chemokine ligand 20 increases expression ISO Tacrolimus results in increased expression of CCL20 mRNA CTD PMID:23958496 NCBI chr 9:88,918,359...88,921,017
Ensembl chr 9:88,918,433...88,921,001
JBrowse link
G Ccl5 C-C motif chemokine ligand 5 decreases expression
increases expression
multiple interactions
ISO Tacrolimus results in decreased expression of CCL5 mRNA
Tacrolimus results in increased expression of CCL5 mRNA
7-oxozeanol inhibits the reaction [Tacrolimus results in increased expression of CCL5 mRNA]; alpha-cyano-(3,4-dihydroxy)-N-benzylcinnamide inhibits the reaction [Tacrolimus results in increased expression of CCL5 mRNA]; ethyl 6-(N-(2-chloro-4-fluorophenyl)sulfamoyl)cyclohex-1-ene-1-carboxylate inhibits the reaction [Tacrolimus results in increased expression of CCL5 mRNA]; parthenolide inhibits the reaction [Tacrolimus results in increased expression of CCL5 mRNA]; pyrazolanthrone inhibits the reaction [Tacrolimus results in increased expression of CCL5 mRNA]; salubrinal inhibits the reaction [Tacrolimus results in increased expression of CCL5 mRNA]; sulforafan inhibits the reaction [Tacrolimus results in increased expression of CCL5 mRNA]
CTD PMID:15948978, PMID:23958496, PMID:25270620 NCBI chr10:70,739,764...70,744,303
Ensembl chr10:70,739,800...70,744,315
JBrowse link
G Ccl6 chemokine (C-C motif) ligand 6 increases expression EXP
ISO
Tacrolimus results in increased expression of CCL6 mRNA CTD PMID:21865292, PMID:29362864 NCBI chr10:70,798,118...70,802,750
Ensembl chr10:70,797,124...70,802,782
JBrowse link
G Ccl7 C-C motif chemokine ligand 7 increases expression ISO Tacrolimus results in increased expression of CCL7 mRNA CTD PMID:23958496, PMID:29362864 NCBI chr10:69,423,083...69,424,933
Ensembl chr10:69,423,086...69,424,979
JBrowse link
G Ccna2 cyclin A2 increases expression ISO Tacrolimus results in increased expression of CCNA2 mRNA CTD PMID:29362864 NCBI chr 2:123,274,727...123,282,266
Ensembl chr 2:123,275,881...123,282,214
JBrowse link
G Ccnb2 cyclin B2 decreases expression
increases expression
ISO Tacrolimus results in decreased expression of CCNB2 mRNA
Tacrolimus results in increased expression of CCNB2 mRNA
CTD PMID:16574167, PMID:29362864 NCBI chr 8:76,847,972...76,861,165 JBrowse link
G Ccr2 C-C motif chemokine receptor 2 increases expression ISO Tacrolimus results in increased expression of CCR2 mRNA CTD PMID:29362864
G Ccr3 C-C motif chemokine receptor 3 decreases expression ISO Tacrolimus results in decreased expression of CCR3 mRNA CTD PMID:15948978 NCBI chr 8:133,026,539...133,040,999
Ensembl chr 8:133,029,625...133,040,997
JBrowse link
G Ccrl2 C-C motif chemokine receptor like 2 increases expression ISO Tacrolimus results in increased expression of CCRL2 mRNA CTD PMID:23958496 NCBI chr 8:119,324,298...119,326,954
Ensembl chr 8:119,324,613...119,326,938
JBrowse link
G Cd2 Cd2 molecule multiple interactions ISO Tacrolimus inhibits the reaction [CD2 protein results in increased expression of IL2 protein] CTD PMID:1705513 NCBI chr 2:203,666,706...203,680,073
Ensembl chr 2:203,666,637...203,680,083
JBrowse link
G Cd44 CD44 molecule (Indian blood group) increases expression EXP Tacrolimus results in increased expression of CD44 mRNA CTD PMID:21865292 NCBI chr 3:92,695,083...92,783,820
Ensembl chr 3:92,696,313...92,783,658
JBrowse link
G Cd68 Cd68 molecule increases expression EXP Tacrolimus results in increased expression of CD68 mRNA CTD PMID:21865292 NCBI chr10:56,268,726...56,270,605
Ensembl chr10:56,268,720...56,270,640
JBrowse link
G Cd74 CD74 molecule increases expression ISO Tacrolimus results in increased expression of CD74 mRNA CTD PMID:23958496 NCBI chr18:56,071,420...56,080,851
Ensembl chr18:56,071,478...56,080,849
JBrowse link
G Cd80 Cd80 molecule decreases expression ISO Tacrolimus results in decreased expression of CD80 protein CTD PMID:15241357 NCBI chr11:64,815,201...64,855,293
Ensembl chr11:64,827,635...64,855,353
JBrowse link
G Cd83 CD83 molecule increases expression ISO Tacrolimus results in increased expression of CD83 mRNA CTD PMID:29362864 NCBI chr17:24,416,651...24,435,790
Ensembl chr17:24,416,651...24,435,790
JBrowse link
G Cd86 CD86 molecule decreases expression ISO Tacrolimus results in decreased expression of CD86 protein CTD PMID:15241357 NCBI chr11:67,060,305...67,117,990
Ensembl chr11:67,082,193...67,118,795
JBrowse link
G Cdca3 cell division cycle associated 3 increases expression ISO Tacrolimus results in increased expression of CDCA3 mRNA CTD PMID:29362864 NCBI chr 4:157,347,876...157,351,889
Ensembl chr 4:157,348,020...157,351,604
JBrowse link
G Cdca5 cell division cycle associated 5 increases expression ISO Tacrolimus results in increased expression of CDCA5 mRNA CTD PMID:29362864 NCBI chr 1:221,448,661...221,462,235
Ensembl chr 1:221,448,661...221,462,233
JBrowse link
G Cdca8 cell division cycle associated 8 increases expression ISO Tacrolimus results in increased expression of CDCA8 mRNA CTD PMID:29362864 NCBI chr 5:142,911,310...142,933,536
Ensembl chr 5:142,911,305...142,933,526
JBrowse link
G Cdh1 cadherin 1 decreases expression ISO Tacrolimus results in decreased expression of CDH1 protein CTD PMID:22416070 NCBI chr19:38,768,467...38,838,395
Ensembl chr19:38,768,467...38,838,395
JBrowse link
G Cdh11 cadherin 11 increases expression ISO Tacrolimus results in increased expression of CDH11 mRNA CTD PMID:29362864 NCBI chr19:2,391,181...2,551,245
Ensembl chr19:2,393,059...2,551,245
JBrowse link
G Cdh16 cadherin 16 decreases expression ISO Tacrolimus results in decreased expression of CDH16 mRNA CTD PMID:22416070 NCBI chr19:568,329...578,513
Ensembl chr19:568,287...578,520
JBrowse link
G Cdkn1b cyclin-dependent kinase inhibitor 1B increases expression EXP Tacrolimus results in increased expression of CDKN1B mRNA CTD PMID:21865292 NCBI chr 4:168,689,043...168,694,159
Ensembl chr 4:168,689,163...168,693,964
JBrowse link
G Cebpa CCAAT/enhancer binding protein alpha increases expression ISO Tacrolimus results in increased expression of CEBPA mRNA CTD PMID:29362864 NCBI chr 1:91,363,492...91,366,164
Ensembl chr 1:91,363,492...91,366,164
JBrowse link
G Cenpw centromere protein W increases expression ISO Tacrolimus results in increased expression of CENPW mRNA CTD PMID:29362864 NCBI chr 1:29,915,443...29,920,598
Ensembl chr 1:29,915,443...29,920,598
JBrowse link
G Cfi complement factor I increases expression EXP Tacrolimus results in increased expression of CFI mRNA CTD PMID:21865292 NCBI chr 2:235,264,149...235,305,779
Ensembl chr 2:235,264,219...235,305,781
JBrowse link
G Ckap2 cytoskeleton associated protein 2 increases expression ISO Tacrolimus results in increased expression of CKAP2 mRNA CTD PMID:29362864 NCBI chr16:74,752,655...74,779,184
Ensembl chr16:74,752,655...74,779,184
JBrowse link
G Ckap4 cytoskeleton-associated protein 4 increases expression EXP Tacrolimus results in increased expression of CKAP4 mRNA CTD PMID:21865292 NCBI chr 7:24,935,243...24,947,595
Ensembl chr 7:24,939,498...24,947,595
JBrowse link
G Cldn1 claudin 1 decreases expression ISO Tacrolimus results in decreased expression of CLDN1 mRNA CTD PMID:22416070 NCBI chr11:77,815,216...77,830,373
Ensembl chr11:77,815,181...77,830,416
JBrowse link
G Cldn4 claudin 4 increases expression EXP Tacrolimus results in increased expression of CLDN4 mRNA CTD PMID:21865292 NCBI chr12:24,761,210...24,763,008
Ensembl chr12:24,761,210...24,763,005
JBrowse link
G Cldn7 claudin 7 increases expression EXP Tacrolimus results in increased expression of CLDN7 mRNA CTD PMID:21865292 NCBI chr10:56,576,326...56,578,632
Ensembl chr10:56,576,428...56,578,626
JBrowse link
G Clec7a C-type lectin domain containing 7A increases expression ISO Tacrolimus results in increased expression of CLEC7A mRNA CTD PMID:29362864 NCBI chr 4:163,216,152...163,227,367
Ensembl chr 4:163,216,163...163,227,334
JBrowse link
G Clk3 CDC-like kinase 3 increases expression ISO Tacrolimus results in increased expression of CLK3 mRNA CTD PMID:25270620 NCBI chr 8:62,528,135...62,543,550
Ensembl chr 8:62,528,225...62,542,622
JBrowse link
G Clu clusterin increases expression EXP Tacrolimus results in increased expression of CLU mRNA CTD PMID:21865292 NCBI chr15:42,626,612...42,665,858
Ensembl chr15:42,640,146...42,665,857
JBrowse link
G Coch cochlin increases expression ISO Tacrolimus results in increased expression of COCH mRNA CTD PMID:25270620 NCBI chr 6:72,359,702...72,373,710
Ensembl chr 6:72,359,791...72,373,695
JBrowse link
G Col1a1 collagen type I alpha 1 chain increases expression ISO Tacrolimus results in increased expression of COL1A1 mRNA CTD PMID:29362864 NCBI chr10:82,745,801...82,762,790
Ensembl chr10:82,745,801...82,762,789
JBrowse link
G Col1a2 collagen type I alpha 2 chain increases expression ISO Tacrolimus results in increased expression of COL1A2 mRNA CTD PMID:29362864 NCBI chr 4:31,534,225...31,569,152
Ensembl chr 4:31,534,225...31,569,151
JBrowse link
G Col3a1 collagen type III alpha 1 chain increases expression ISO Tacrolimus results in increased expression of COL3A1 mRNA CTD PMID:29362864 NCBI chr 9:52,023,295...52,059,221
Ensembl chr 9:52,023,295...52,059,217
JBrowse link
G Cops8 COP9 signalosome subunit 8 increases expression ISO Tacrolimus results in increased expression of COPS8 mRNA CTD PMID:25270620 NCBI chr 9:97,772,224...97,782,055
Ensembl chr 9:97,772,184...97,782,067
JBrowse link
G Cp ceruloplasmin increases expression EXP Tacrolimus results in increased expression of CP mRNA CTD PMID:21865292 NCBI chr 2:104,744,249...104,803,034
Ensembl chr 2:104,744,461...104,799,853
JBrowse link
G Creb3l3 cAMP responsive element binding protein 3-like 3 decreases expression ISO Tacrolimus results in decreased expression of CREB3L3 mRNA CTD PMID:25270620 NCBI chr 7:11,490,852...11,499,287
Ensembl chr 7:11,490,852...11,499,282
JBrowse link
G Creld2 cysteine-rich with EGF-like domains 2 increases expression ISO Tacrolimus results in increased expression of CRELD2 mRNA CTD PMID:25270620 NCBI chr 7:129,812,746...129,819,641
Ensembl chr 7:129,812,789...129,819,634
JBrowse link
G Csf1 colony stimulating factor 1 increases expression ISO Tacrolimus results in increased expression of CSF1 mRNA CTD PMID:23958496 NCBI chr 2:210,522,370...210,550,546
Ensembl chr 2:210,522,375...210,550,560
JBrowse link
G Csf2 colony stimulating factor 2 decreases expression
increases expression
multiple interactions
ISO Tacrolimus results in decreased expression of CSF2 protein
Tacrolimus results in increased expression of CSF2 mRNA
Sirolimus inhibits the reaction [Tacrolimus inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of CSF2 protein]]; Tacrolimus inhibits the reaction [[Calcimycin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of CSF2 protein]
CTD PMID:1376361, PMID:11407316, PMID:23958496 NCBI chr10:39,602,089...39,604,070
Ensembl chr10:39,602,089...39,604,070
JBrowse link
G Csf2rb colony stimulating factor 2 receptor subunit beta increases expression ISO Tacrolimus results in increased expression of CSF2RB2 mRNA CTD PMID:29362864 NCBI chr 7:119,554,383...119,568,248
Ensembl chr 7:119,554,354...119,568,776
JBrowse link
G Ctsl cathepsin L multiple interactions
increases expression
ISO
EXP
Tacrolimus inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CTSL protein]
Tacrolimus results in increased expression of CTSL mRNA
CTD PMID:18172886, PMID:21865292, PMID:25270620 NCBI chr17:1,873,105...1,879,266
Ensembl chr17:1,872,848...1,879,279
JBrowse link
G Cxcl10 C-X-C motif chemokine ligand 10 increases expression EXP
ISO
Tacrolimus results in increased expression of CXCL10 mRNA CTD PMID:21865292, PMID:23958496, PMID:25270620 NCBI chr14:17,210,733...17,212,930
Ensembl chr14:17,210,733...17,212,930
JBrowse link
G Cxcl11 C-X-C motif chemokine ligand 11 increases expression ISO Tacrolimus results in increased expression of CXCL11 mRNA CTD PMID:23958496 NCBI chr14:17,195,395...17,198,170
Ensembl chr14:17,195,014...17,198,291
JBrowse link
G Cyba cytochrome b-245 alpha chain multiple interactions
increases expression
ISO Ramipril inhibits the reaction [Tacrolimus results in increased expression of CYBA mRNA] CTD PMID:12352326 NCBI chr19:55,249,634...55,257,824
Ensembl chr19:55,249,616...55,257,876
JBrowse link
G Cyp27b1 cytochrome P450, family 27, subfamily b, polypeptide 1 increases expression EXP Tacrolimus results in increased expression of CYP27B1 mRNA CTD PMID:21865292 NCBI chr 7:70,333,150...70,340,006
Ensembl chr 7:70,335,061...70,340,005
JBrowse link
G Cyp2c6v1 cytochrome P450, family 2, subfamily C, polypeptide 6, variant 1 multiple interactions ISO CYP2C19 affects the reaction [Lansoprazole affects the susceptibility to Tacrolimus]; CYP2C19 affects the susceptibility to [Tacrolimus co-treated with Lansoprazole]; CYP2C19 affects the susceptibility to [Tacrolimus co-treated with Rabeprazole]; CYP2C19 gene mutant form affects the susceptibility to [Lansoprazole co-treated with Tacrolimus] CTD PMID:15010519, PMID:15285851, PMID:17377957 NCBI chr 1:147,713,879...147,814,410
Ensembl chr 1:147,713,892...147,888,007
JBrowse link
G Cyp3a9 cytochrome P450, family 3, subfamily a, polypeptide 9 multiple interactions
decreases methylation
affects metabolic processing
affects response to substance
ISO CYP3A5 affects the susceptibility to [Tacrolimus co-treated with Lansoprazole]; CYP3A5 affects the susceptibility to [Tacrolimus co-treated with Rabeprazole]; CYP3A5 gene polymorphism affects the reaction [Ketoconazole results in decreased metabolism of Tacrolimus]
CYP3A5 protein results in decreased methylation of Tacrolimus
CYP3A5 gene polymorphism affects the metabolism of Tacrolimus; CYP3A5 gene SNP affects the metabolism of Tacrolimus; CYP3A5 protein affects the metabolism of Tacrolimus; CYP3A5 protein polymorphism affects the metabolism of Tacrolimus
CYP3A5 gene affects the susceptibility to Tacrolimus
CTD PMID:15502717, PMID:15723604, PMID:15729180, PMID:15808586, PMID:15919447, PMID:15951320, PMID:15964336, PMID:17377957, PMID:19384264 NCBI chr12:19,074,288...19,114,491
Ensembl chr12:19,074,583...19,114,399
JBrowse link
G Dcn decorin increases expression ISO Tacrolimus results in increased expression of DCN mRNA CTD PMID:29362864 NCBI chr 7:38,742,250...38,782,282
Ensembl chr 7:38,742,051...38,782,323
JBrowse link
G Ddit3 DNA-damage inducible transcript 3 multiple interactions
increases expression
ISO salubrinal promotes the reaction [Tacrolimus results in increased expression of DDIT3 protein]
Tacrolimus results in increased expression of DDIT3 mRNA
CTD PMID:23958496, PMID:25270620 NCBI chr 7:70,578,564...70,585,074
Ensembl chr 7:70,580,198...70,585,084
JBrowse link
G Ddit4l DNA-damage-inducible transcript 4-like decreases expression EXP Tacrolimus results in decreased expression of DDIT4L mRNA CTD PMID:21865292 NCBI chr 2:242,882,219...242,885,088
Ensembl chr 2:242,882,306...242,885,131
JBrowse link
G Dhcr24 24-dehydrocholesterol reductase decreases expression ISO Tacrolimus results in decreased expression of DHCR24 mRNA CTD PMID:25270620 NCBI chr 5:126,164,708...126,188,926
Ensembl chr 5:126,164,674...126,191,206
JBrowse link
G Dnajc30 DnaJ heat shock protein family (Hsp40) member C30 decreases expression ISO Tacrolimus results in decreased expression of DNAJC30 mRNA CTD PMID:25270620 NCBI chr12:24,668,398...24,669,464
Ensembl chr12:24,668,398...24,669,464
JBrowse link
G Dnm1l dynamin 1-like multiple interactions ISO PINK1 protein affects the reaction [Tacrolimus results in increased phosphorylation of DNM1L protein]
Tacrolimus inhibits the reaction [ferric ammonium citrate results in decreased phosphorylation of DNM1L protein]
CTD PMID:19492085, PMID:26318285 NCBI chr11:88,830,968...88,882,271
Ensembl chr11:88,830,957...88,880,198
JBrowse link
G Doc2a double C2 domain alpha decreases expression ISO Tacrolimus results in decreased expression of DOC2A mRNA CTD PMID:25270620 NCBI chr 1:198,282,828...198,288,611
Ensembl chr 1:198,284,473...198,288,113
JBrowse link
G Dock10 dedicator of cytokinesis 10 increases expression ISO Tacrolimus results in increased expression of DOCK10 mRNA CTD PMID:29362864 NCBI chr 9:86,424,638...86,571,854
NCBI chr 9:86,312,470...86,423,054
Ensembl chr 9:86,312,501...86,571,870
JBrowse link
G Dpp4 dipeptidylpeptidase 4 increases activity
multiple interactions
EXP Tacrolimus results in increased activity of DPP4 protein
MK0626 inhibits the reaction [Tacrolimus results in increased activity of DPP4 protein]
CTD PMID:24959755 NCBI chr 3:48,291,055...48,372,672
Ensembl chr 3:48,291,055...48,372,672
JBrowse link
G Drd2 dopamine receptor D2 affects activity
multiple interactions
EXP Tacrolimus affects the activity of DRD2 protein
Sulpiride inhibits the reaction [Tacrolimus affects the activity of DRD2 protein]
CTD PMID:15332494 NCBI chr 8:53,678,777...53,743,643
Ensembl chr 8:53,678,777...53,743,642
JBrowse link
G Ech1 enoyl-CoA hydratase 1 decreases expression ISO Tacrolimus results in decreased expression of ECH1 mRNA CTD PMID:25270620 NCBI chr 1:87,009,798...87,015,996
Ensembl chr 1:87,009,730...87,016,005
JBrowse link
G Edem1 ER degradation enhancing alpha-mannosidase like protein 1 increases expression ISO Tacrolimus results in increased expression of EDEM1 mRNA CTD PMID:25270620 NCBI chr 4:140,886,644...140,918,654
Ensembl chr 4:140,886,545...140,915,779
JBrowse link
G Edn1 endothelin 1 increases expression EXP Tacrolimus results in increased expression of EDN1 mRNA; Tacrolimus results in increased expression of EDN1 protein CTD PMID:9517403, PMID:9931093 NCBI chr17:22,136,814...22,143,745
Ensembl chr17:22,137,324...22,143,324
JBrowse link
G Ednra endothelin receptor type A increases activity
increases expression
EXP Tacrolimus results in increased activity of EDNRA protein
Tacrolimus results in increased expression of EDNRA mRNA
CTD PMID:8587392, PMID:15964565 NCBI chr19:33,928,356...33,991,703
Ensembl chr19:33,928,356...33,991,703
JBrowse link
G Efemp2 EGF containing fibulin extracellular matrix protein 2 increases expression ISO Tacrolimus results in increased expression of EFEMP2 mRNA CTD PMID:29362864 NCBI chr 1:220,853,695...220,861,420
Ensembl chr 1:220,854,403...220,861,420
JBrowse link
G Egr1 early growth response 1 increases expression EXP Tacrolimus results in increased expression of EGR1 mRNA CTD PMID:21865292 NCBI chr18:27,657,903...27,660,101
Ensembl chr18:27,657,628...27,661,429
JBrowse link
G Egr2 early growth response 2 increases expression EXP Tacrolimus results in increased expression of EGR2 mRNA CTD PMID:21865292 NCBI chr20:22,452,170...22,461,018
Ensembl chr20:22,454,463...22,459,025
JBrowse link
G Eif4ebp1 eukaryotic translation initiation factor 4E binding protein 1 multiple interactions ISO Tacrolimus inhibits the reaction [Sirolimus results in decreased phosphorylation of and results in increased activity of EIF4EBP1 protein] CTD PMID:8599949 NCBI chr16:68,954,860...68,968,248
Ensembl chr16:68,954,875...68,968,248
JBrowse link
G Elac2 elaC ribonuclease Z 2 decreases expression ISO Tacrolimus results in decreased expression of ELAC2 mRNA CTD PMID:25270620 NCBI chr10:51,478,378...51,501,167
Ensembl chr10:51,478,378...51,501,165
JBrowse link
G Ern1 endoplasmic reticulum to nucleus signaling 1 increases phosphorylation ISO Tacrolimus results in increased phosphorylation of ERN1 protein CTD PMID:23958496 NCBI chr10:94,588,555...94,682,072
Ensembl chr10:94,588,555...94,681,914
JBrowse link
G Ero1a endoplasmic reticulum oxidoreductase 1 alpha increases expression ISO Tacrolimus results in increased expression of ERO1A mRNA CTD PMID:23958496 NCBI chr15:19,619,947...19,655,381
Ensembl chr15:19,619,973...19,655,381
JBrowse link
G Exosc4 exosome component 4 decreases expression ISO Tacrolimus results in decreased expression of EXOSC4 mRNA CTD PMID:25270620 NCBI chr 7:117,390,302...117,393,044
Ensembl chr 7:117,390,285...117,393,719
JBrowse link
G F2r coagulation factor II (thrombin) receptor decreases expression ISO Tacrolimus results in decreased expression of F2R mRNA CTD PMID:25270620 NCBI chr 2:26,118,760...26,135,340
Ensembl chr 2:26,118,760...26,135,340
JBrowse link
G Fabp2 fatty acid binding protein 2 decreases expression ISO Tacrolimus results in decreased expression of FABP2 mRNA CTD PMID:25270620 NCBI chr 2:227,080,912...227,083,654
Ensembl chr 2:227,080,924...227,083,501
JBrowse link
G Fas Fas cell surface death receptor multiple interactions ISO Tacrolimus inhibits the reaction [FAS protein results in increased activity of CASP3 protein]; Tacrolimus inhibits the reaction [FAS protein results in increased activity of CASP8 protein]; Tacrolimus inhibits the reaction [FAS protein results in increased activity of CASP9 protein] CTD PMID:15548389 NCBI chr 1:252,589,785...252,624,790
Ensembl chr 1:252,589,785...252,624,790
JBrowse link
G Faslg Fas ligand decreases secretion ISO Tacrolimus results in decreased secretion of FASLG protein CTD PMID:11692113 NCBI chr13:79,696,811...79,717,581
Ensembl chr13:79,698,445...79,705,705
JBrowse link
G Fbln1 fibulin 1 increases expression EXP Tacrolimus results in increased expression of FBLN1 mRNA CTD PMID:21865292 NCBI chr 7:126,096,793...126,176,468
Ensembl chr 7:126,096,793...126,176,468
JBrowse link
G Fga fibrinogen alpha chain increases expression EXP Tacrolimus results in increased expression of FGA mRNA CTD PMID:21865292 NCBI chr 2:181,997,562...182,013,726
Ensembl chr 2:182,006,242...182,013,763
JBrowse link
G Fgb fibrinogen beta chain increases expression EXP Tacrolimus results in increased expression of FGB mRNA CTD PMID:21865292 NCBI chr 2:182,028,044...182,035,026
Ensembl chr 2:182,027,115...182,038,178
JBrowse link
G Fgd2 FYVE, RhoGEF and PH domain containing 2 increases expression ISO Tacrolimus results in increased expression of FGD2 mRNA CTD PMID:29362864 NCBI chr20:6,973,356...6,990,026
Ensembl chr20:6,973,398...6,990,023
JBrowse link
G Fgf21 fibroblast growth factor 21 decreases expression ISO Tacrolimus results in decreased expression of FGF21 mRNA CTD PMID:25270620 NCBI chr 1:101,595,579...101,596,822
Ensembl chr 1:101,595,579...101,596,822
JBrowse link
G Fgl2 fibrinogen-like 2 increases expression EXP
ISO
Tacrolimus results in increased expression of FGL2 mRNA CTD PMID:21865292, PMID:29362864 NCBI chr 4:10,323,598...10,329,241
Ensembl chr 4:10,323,607...10,329,241
JBrowse link
G Fhl2 four and a half LIM domains 2 increases expression ISO Tacrolimus results in increased expression of FHL2 mRNA CTD PMID:29362864 NCBI chr 9:49,920,611...49,994,906
Ensembl chr 9:49,920,854...49,950,093
JBrowse link
G Fkbp1a FKBP prolyl isomerase 1A multiple interactions
increases expression
ISO
EXP
[Tacrolimus binds to FKBP1A protein] inhibits the reaction [Sirolimus binds to FKBP1A protein]; [Tacrolimus inhibits the reaction [FKBP1A protein binds to ACVR1B protein]] which results in decreased ubiquitination of ACVR1B protein; Tacrolimus inhibits the reaction [FKBP1A protein binds to and results in decreased activity of ACVR1B protein]; Tacrolimus inhibits the reaction [FKBP1A protein promotes the reaction [SMURF1 protein binds to SMAD7 protein binds to ACVR1B protein]]
Tacrolimus results in increased expression of FKBP1A protein
CTD PMID:10361256, PMID:11041285, PMID:16720724 NCBI chr 3:147,042,944...147,062,725
Ensembl chr 3:147,042,944...147,062,724
JBrowse link
G Fkbp5 FKBP prolyl isomerase 5 multiple interactions ISO Tacrolimus inhibits the reaction [NR3C1 protein binds to FKBP5 protein] CTD PMID:15697228 NCBI chr20:7,976,704...8,097,290
Ensembl chr20:7,976,713...8,019,020
JBrowse link
G Flt3 Fms related receptor tyrosine kinase 3 increases expression ISO Tacrolimus results in increased expression of FLT3 mRNA CTD PMID:29362864 NCBI chr12:9,360,439...9,437,004
Ensembl chr12:9,360,672...9,436,570
JBrowse link
G Fmo2 flavin containing dimethylaniline monoxygenase 2 increases expression ISO Tacrolimus results in increased expression of FMO2 mRNA CTD PMID:21621594 NCBI chr13:80,752,526...80,775,264
Ensembl chr13:80,755,058...80,775,264
JBrowse link
G Fn1 fibronectin 1 multiple interactions
increases expression
ISO Tacrolimus inhibits the reaction [NPR1 protein affects the expression of FN1 mRNA]
Tacrolimus results in increased expression of FN1 mRNA
CTD PMID:15939815, PMID:29362864 NCBI chr 9:78,900,111...78,969,018
Ensembl chr 9:78,900,103...78,969,078
JBrowse link
G Fndc3a fibronectin type III domain containing 3a increases expression ISO Tacrolimus results in increased expression of FNDC3A mRNA CTD PMID:25270620 NCBI chr15:54,378,865...54,582,954
Ensembl chr15:54,381,044...54,528,480
JBrowse link
G Fos Fos proto-oncogene, AP-1 transcription factor subunit increases expression ISO Tacrolimus results in increased expression of FOS mRNA CTD PMID:23958496 NCBI chr 6:109,300,433...109,303,299
Ensembl chr 6:109,300,433...109,303,299
JBrowse link
G Fosl1 FOS like 1, AP-1 transcription factor subunit increases expression ISO Tacrolimus results in increased expression of FOSL1 mRNA CTD PMID:23958496 NCBI chr 1:220,826,560...220,835,066
Ensembl chr 1:220,826,560...220,835,066
JBrowse link
G Gbp1 guanylate binding protein 1 decreases expression ISO Tacrolimus results in decreased expression of GBP1 mRNA CTD PMID:21621594 NCBI chr 2:248,343,334...248,423,402
Ensembl chr 2:248,398,917...248,409,570
JBrowse link
G Gc GC, vitamin D binding protein decreases expression
increases expression
EXP
ISO
Tacrolimus results in decreased expression of GC mRNA
Tacrolimus results in increased expression of GC mRNA
CTD PMID:21865292, PMID:29362864 NCBI chr14:20,267,023...20,302,577
Ensembl chr14:20,266,891...20,302,581
JBrowse link
G Gcg glucagon multiple interactions
decreases secretion
EXP MK0626 inhibits the reaction [Tacrolimus results in decreased secretion of GCG protein modified form] CTD PMID:24959755 NCBI chr 3:48,442,635...48,451,650
Ensembl chr 3:48,442,635...48,451,650
JBrowse link
G Gins2 GINS complex subunit 2 increases expression ISO Tacrolimus results in increased expression of GINS2 mRNA CTD PMID:29362864 NCBI chr19:54,151,048...54,163,701
Ensembl chr19:54,151,048...54,163,608
JBrowse link
G Gjb1 gap junction protein, beta 1 increases expression ISO Tacrolimus results in increased expression of GJB1 mRNA CTD PMID:21621594 NCBI chr  X:71,272,030...71,279,973
Ensembl chr  X:71,272,042...71,279,977
JBrowse link
G Gldc glycine decarboxylase decreases expression ISO Tacrolimus results in decreased expression of GLDC mRNA CTD PMID:25270620 NCBI chr 1:248,295,140...248,377,122
Ensembl chr 1:248,297,331...248,377,093
JBrowse link
G Glp1r glucagon-like peptide 1 receptor decreases expression
multiple interactions
EXP Tacrolimus results in decreased expression of GLP1R protein
MK0626 inhibits the reaction [Tacrolimus results in decreased expression of GLP1R protein]
CTD PMID:24959755 NCBI chr20:9,586,075...9,626,228
Ensembl chr20:9,586,075...9,626,228
JBrowse link
G Gpihbp1 glycosylphosphatidylinositol anchored high density lipoprotein binding protein 1 decreases expression ISO Tacrolimus results in decreased expression of GPIHBP1 mRNA CTD PMID:29362864 NCBI chr 7:116,632,496...116,635,543
Ensembl chr 7:116,632,506...116,634,293
JBrowse link
G Gpn2 GPN-loop GTPase 2 increases expression ISO Tacrolimus results in increased expression of GPN2 mRNA CTD PMID:25270620 NCBI chr 5:151,806,458...151,813,954
Ensembl chr 5:151,806,458...151,813,954
JBrowse link
G Gpnmb glycoprotein nmb increases expression EXP Tacrolimus results in increased expression of GPNMB mRNA CTD PMID:21865292 NCBI chr 4:78,694,447...78,715,685
Ensembl chr 4:78,694,447...78,715,683
JBrowse link
G Grn granulin precursor increases expression ISO Tacrolimus results in increased expression of GRN mRNA CTD PMID:25270620 NCBI chr10:90,377,103...90,383,207
Ensembl chr10:90,376,933...90,383,205
JBrowse link
G Gsk3a glycogen synthase kinase 3 alpha multiple interactions
increases phosphorylation
ISO [GSK3A protein co-treated with GSK3B protein] affects the reaction [Tacrolimus results in increased expression of SNAI1 protein]
Tacrolimus results in increased phosphorylation of GSK3A protein
CTD PMID:22416070 NCBI chr 1:82,097,244...82,108,238
Ensembl chr 1:82,097,247...82,108,203
JBrowse link
G Gsk3b glycogen synthase kinase 3 beta multiple interactions
increases phosphorylation
ISO [GSK3A protein co-treated with GSK3B protein] affects the reaction [Tacrolimus results in increased expression of SNAI1 protein]
Tacrolimus results in increased phosphorylation of GSK3B protein
CTD PMID:22416070 NCBI chr11:65,060,884...65,208,842
Ensembl chr11:65,066,235...65,209,268
JBrowse link
G Gtpbp4 GTP binding protein 4 decreases expression EXP Tacrolimus results in decreased expression of GTPBP4 mRNA CTD PMID:21865292 NCBI chr17:63,111,086...63,145,618
Ensembl chr17:63,110,254...63,145,577
JBrowse link
G Guca2a guanylate cyclase activator 2A increases expression EXP Tacrolimus results in increased expression of GUCA2A mRNA CTD PMID:21865292 NCBI chr 5:138,685,634...138,687,476
Ensembl chr 5:138,685,624...138,687,816
JBrowse link
G Hadhb hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit beta decreases expression ISO Tacrolimus results in decreased expression of HADHB mRNA CTD PMID:25270620 NCBI chr 6:27,555,408...27,589,539
Ensembl chr 6:27,555,412...27,582,995
JBrowse link
G Havcr1 hepatitis A virus cellular receptor 1 increases expression EXP Tacrolimus results in increased expression of HAVCR1 mRNA CTD PMID:21865292 NCBI chr10:31,813,819...31,860,934
Ensembl chr10:31,813,814...31,848,379
JBrowse link
G Herpud1 homocysteine inducible ER protein with ubiquitin like domain 1 increases expression ISO Tacrolimus results in increased expression of HERPUD1 mRNA CTD PMID:23958496, PMID:25270620 NCBI chr19:11,046,905...11,057,440
Ensembl chr19:11,046,909...11,057,254
JBrowse link
G Hexa hexosaminidase subunit alpha increases expression ISO Tacrolimus results in increased expression of HEXA mRNA CTD PMID:25270620 NCBI chr 8:64,325,435...64,350,775
Ensembl chr 8:64,325,435...64,350,773
JBrowse link
G Hgs hepatocyte growth factor-regulated tyrosine kinase substrate increases expression ISO Tacrolimus results in increased expression of HGS mRNA CTD PMID:29380240 NCBI chr10:109,638,944...109,657,460
Ensembl chr10:109,638,767...109,657,456
JBrowse link
G Hk2 hexokinase 2 increases expression ISO Tacrolimus results in increased expression of HK2 mRNA CTD PMID:29362864 NCBI chr 4:113,559,396...113,609,897
Ensembl chr 4:113,559,427...113,610,243
JBrowse link
G Hk3 hexokinase 3 increases expression ISO Tacrolimus results in increased expression of HK3 mRNA CTD PMID:29362864 NCBI chr17:10,134,726...10,152,976
Ensembl chr17:10,137,974...10,152,956
JBrowse link
G Hmgcs2 3-hydroxy-3-methylglutaryl-CoA synthase 2 decreases expression ISO Tacrolimus results in decreased expression of HMGCS2 mRNA CTD PMID:25270620 NCBI chr 2:200,452,623...200,480,785
Ensembl chr 2:200,452,624...200,479,423
JBrowse link
G Hmox1 heme oxygenase 1 increases expression
decreases expression
multiple interactions
ISO
EXP
Tacrolimus results in increased expression of HMOX1 mRNA; Tacrolimus results in increased expression of HMOX1 protein
Tacrolimus results in decreased expression of HMOX1 protein
MK0626 inhibits the reaction [Tacrolimus results in decreased expression of HMOX1 protein]
CTD PMID:23958496, PMID:24959755, PMID:26260164, PMID:29362864 NCBI chr19:14,508,634...14,515,455
Ensembl chr19:14,508,616...14,515,456
JBrowse link
G Hnf1b HNF1 homeobox B decreases expression ISO Tacrolimus results in decreased expression of HNF1B mRNA CTD PMID:22416070 NCBI chr10:71,159,863...71,218,902
Ensembl chr10:71,159,869...71,218,902
JBrowse link
G Hsdl2 hydroxysteroid dehydrogenase like 2 decreases expression ISO Tacrolimus results in decreased expression of HSDL2 mRNA CTD PMID:25270620 NCBI chr 5:76,812,881...76,848,853
Ensembl chr 5:76,812,931...76,848,101
JBrowse link
G Hspa5 heat shock protein family A (Hsp70) member 5 increases expression ISO Tacrolimus results in increased expression of HSPA5 mRNA CTD PMID:25270620 NCBI chr 3:13,838,304...13,842,763
Ensembl chr 3:13,838,304...13,842,762
JBrowse link
G Hspa8 heat shock protein family A (Hsp70) member 8 multiple interactions
increases expression
EXP Tacrolimus inhibits the reaction [Acrylamide results in decreased expression of HSPA8 protein]
Tacrolimus results in increased expression of HSPA8 protein
CTD PMID:15081597 NCBI chr 8:44,989,401...44,993,261
Ensembl chr 8:44,990,014...44,993,179
JBrowse link
G Icam1 intercellular adhesion molecule 1 decreases expression
increases expression
EXP
ISO
Tacrolimus results in decreased expression of ICAM1; Tacrolimus results in decreased expression of ICAM1 protein
Tacrolimus results in increased expression of ICAM1 mRNA
CTD PMID:9794552, PMID:10385251, PMID:23958496 NCBI chr 8:22,035,287...22,047,049
Ensembl chr 8:22,035,256...22,047,059
JBrowse link
G Id1 inhibitor of DNA binding 1, HLH protein increases expression ISO Tacrolimus results in increased expression of ID1 mRNA CTD PMID:25270620, PMID:29362864 NCBI chr 3:148,214,623...148,216,715
Ensembl chr 3:148,215,540...148,216,718
JBrowse link
G Id2 inhibitor of DNA binding 2 increases expression ISO Tacrolimus results in increased expression of ID2 mRNA CTD PMID:25270620 NCBI chr 6:44,360,077...44,361,908
Ensembl chr 6:44,348,501...44,363,915
JBrowse link
G Id3 inhibitor of DNA binding 3, HLH protein increases expression ISO Tacrolimus results in increased expression of ID3 mRNA CTD PMID:29362864 NCBI chr 5:154,489,603...154,491,172
Ensembl chr 5:154,489,590...154,491,223
JBrowse link
G Id4 inhibitor of DNA binding 4, HLH protein increases expression ISO Tacrolimus results in increased expression of ID4 mRNA CTD PMID:25270620 NCBI chr17:16,692,557...16,695,126
Ensembl chr17:16,692,557...16,695,126
JBrowse link
G Idi1 isopentenyl-diphosphate delta isomerase 1 decreases expression ISO Tacrolimus results in decreased expression of IDI1 mRNA CTD PMID:25270620 NCBI chr17:57,976,266...57,984,036
Ensembl chr17:57,976,268...57,984,036
JBrowse link
G Ifi27l2b interferon, alpha-inducible protein 27 like 2B increases expression ISO Tacrolimus results in increased expression of IFI27L2A mRNA CTD PMID:29362864 NCBI chr 6:127,336,305...127,337,791
Ensembl chr 6:127,336,305...127,337,791
JBrowse link
G Ifng interferon gamma multiple interactions
decreases expression
decreases secretion
ISO
EXP
[Tacrolimus co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IFNG mRNA; Tacrolimus inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of IFNG protein]; Tacrolimus inhibits the reaction [enterotoxin A, Staphylococcal results in increased expression of IFNG protein]; Tacrolimus inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of IFNG mRNA]
Tacrolimus results in decreased expression of IFNG protein
Tacrolimus results in decreased expression of IFNG mRNA; Tacrolimus results in decreased expression of IFNG protein
[Tacrolimus co-treated with TAK 779] results in decreased expression of IFNG protein
Tacrolimus inhibits the reaction [[Lipopolysaccharides co-treated with IFNG protein] results in decreased expression of BCL2 protein]; Tacrolimus inhibits the reaction [[Lipopolysaccharides co-treated with IFNG protein] results in increased activity of CASP3 protein]; Tacrolimus inhibits the reaction [[Lipopolysaccharides co-treated with IFNG protein] results in increased expression of BAX protein]; Tacrolimus inhibits the reaction [[Lipopolysaccharides co-treated with IFNG protein] results in increased expression of TRP53 protein]
Tacrolimus results in decreased secretion of IFNG protein
CTD PMID:1371491, PMID:8986461, PMID:10205001, PMID:11407316, PMID:11692113, PMID:16368244, PMID:20967261, PMID:21515370, PMID:24603311, PMID:29594315 NCBI chr 7:61,337,383...61,341,419
Ensembl chr 7:61,337,381...61,341,419
JBrowse link
G Igf1 insulin-like growth factor 1 increases response to substance EXP IGF1 protein results in increased susceptibility to Tacrolimus CTD PMID:12826230 NCBI chr 7:28,412,123...28,491,815
Ensembl chr 7:28,412,198...28,486,609
JBrowse link
G Igfbp1 insulin-like growth factor binding protein 1 decreases expression
increases expression
EXP Tacrolimus results in decreased expression of IGFBP1 mRNA
Tacrolimus results in increased expression of IGFBP1 mRNA
CTD PMID:21865292 NCBI chr14:87,448,716...87,453,783
Ensembl chr14:87,448,692...87,453,785
JBrowse link
G Igfbp5 insulin-like growth factor binding protein 5 increases expression EXP Tacrolimus results in increased expression of IGFBP5 mRNA CTD PMID:21865292 NCBI chr 9:80,154,230...80,166,813
Ensembl chr 9:80,150,211...80,167,033
JBrowse link
G Il15ra interleukin 15 receptor subunit alpha increases expression ISO Tacrolimus results in increased expression of IL15RA mRNA CTD PMID:23958496 NCBI chr17:70,451,861...70,481,838
Ensembl chr17:70,451,411...70,481,750
JBrowse link
G Il17ra interleukin 17 receptor A increases expression ISO Tacrolimus results in increased expression of IL17RA mRNA CTD PMID:23958496 NCBI chr 4:152,995,865...153,018,394
Ensembl chr 4:152,995,865...153,018,394
JBrowse link
G Il1b interleukin 1 beta increases expression ISO Tacrolimus results in increased expression of IL1B mRNA CTD PMID:29594315 NCBI chr 3:121,876,256...121,882,637
Ensembl chr 3:121,876,263...121,882,726
JBrowse link
G Il1rn interleukin 1 receptor antagonist increases expression ISO Tacrolimus results in increased expression of IL1RN mRNA CTD PMID:23958496 NCBI chr 3:1,449,778...1,468,624
Ensembl chr 3:1,452,644...1,468,614
JBrowse link
G Il2 interleukin 2 multiple interactions
decreases expression
ISO
EXP
[Tacrolimus co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IL2 mRNA; Tacrolimus inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of IL2 protein]; Tacrolimus inhibits the reaction [CD2 protein results in increased expression of IL2 protein]; Tacrolimus inhibits the reaction [enterotoxin A, Staphylococcal results in increased expression of IL2 protein]; Tacrolimus inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of IL2 mRNA]; Tacrolimus inhibits the reaction [Zinc Sulfate inhibits the reaction [Mitogens results in increased expression of IL2 mRNA]]
Tacrolimus results in decreased expression of IL2 mRNA; Tacrolimus results in decreased expression of IL2 protein
Tacrolimus affects the reaction [[9,10-Dimethyl-1,2-benzanthracene co-treated with Tetradecanoylphorbol Acetate] affects the expression of IL2 protein]; Tacrolimus inhibits the reaction [Sirolimus inhibits the reaction [IL2 protein results in increased phosphorylation of RPS6 protein]]
CTD PMID:1371491, PMID:1614535, PMID:1701765, PMID:1705513, PMID:8986461, PMID:11407316, PMID:12126653, PMID:16055081, PMID:24603311, PMID:25770929, PMID:29594315 NCBI chr 2:123,847,150...123,851,854
Ensembl chr 2:123,847,150...123,851,854
JBrowse link
G Il23a interleukin 23 subunit alpha increases expression ISO Tacrolimus results in increased expression of IL23A mRNA CTD PMID:25270620 NCBI chr 7:2,710,609...2,712,723
Ensembl chr 7:2,710,609...2,712,723
JBrowse link
G Il2ra interleukin 2 receptor subunit alpha decreases expression ISO Tacrolimus results in decreased expression of IL2RA protein CTD PMID:1701765 NCBI chr17:70,500,672...70,547,929
Ensembl chr17:70,499,083...70,548,071
JBrowse link
G Il3 interleukin 3 decreases expression
multiple interactions
ISO Tacrolimus results in decreased expression of IL3 protein
Sirolimus inhibits the reaction [Tacrolimus inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of IL3 protein]]; Tacrolimus inhibits the reaction [[Calcimycin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of IL3 protein]
CTD PMID:1376361, PMID:11407316 NCBI chr10:39,620,535...39,622,973
Ensembl chr10:39,620,563...39,622,973
JBrowse link
G Il4 interleukin 4 multiple interactions
decreases expression
ISO
EXP
Tacrolimus inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of IL4 protein]
Tacrolimus results in decreased expression of IL4 mRNA; Tacrolimus results in decreased expression of IL4 protein
Tacrolimus inhibits the reaction [bisphenol A promotes the reaction [NFATC3 protein binds to IL4 promoter]]; Tacrolimus inhibits the reaction [bisphenol A results in increased expression of IL4 protein]; Tacrolimus inhibits the reaction [nonylphenol promotes the reaction [NFATC3 protein binds to IL4 promoter]]; Tacrolimus inhibits the reaction [nonylphenol results in increased expression of IL4 protein]
CTD PMID:1371491, PMID:10685002, PMID:11407316, PMID:12709020, PMID:16368244 NCBI chr10:38,963,979...38,969,531
Ensembl chr10:38,963,979...38,969,531
JBrowse link
G Il5 interleukin 5 multiple interactions
decreases expression
ISO Tacrolimus inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of IL5 protein]
Tacrolimus results in decreased expression of IL5 mRNA; Tacrolimus results in decreased expression of IL5 protein
CTD PMID:1371491, PMID:7540862, PMID:11407316, PMID:15948978 NCBI chr10:39,066,716...39,069,587
Ensembl chr10:39,066,716...39,069,587
JBrowse link
G Il6 interleukin 6 multiple interactions
increases expression
decreases expression
EXP
ISO
[Tacrolimus co-treated with quinapril] results in decreased expression of IL6 protein; [Tacrolimus co-treated with quinapril] results in increased expression of IL6 protein; [Tacrolimus co-treated with Valsartan] results in decreased expression of IL6 protein; [Tacrolimus co-treated with Valsartan] results in increased expression of IL6 protein
Tacrolimus results in increased expression of IL6 mRNA
parthenolide inhibits the reaction [Tacrolimus results in increased expression of IL6 mRNA]; sulforafan inhibits the reaction [Tacrolimus results in increased expression of IL6 mRNA]
Tacrolimus results in increased expression of IL6 protein
Tacrolimus results in decreased expression of IL6 protein
CTD PMID:16549154, PMID:23958496 NCBI chr 4:3,043,231...3,047,807
Ensembl chr 4:3,043,231...3,047,807
JBrowse link
G Imp4 IMP U3 small nucleolar ribonucleoprotein 4 decreases expression ISO Tacrolimus results in decreased expression of IMP4 mRNA CTD PMID:25270620 NCBI chr 9:37,769,959...37,775,097
Ensembl chr 9:37,769,959...37,775,154
JBrowse link
G Ino80e INO80 complex subunit E decreases expression ISO Tacrolimus results in decreased expression of INO80E mRNA CTD PMID:25270620 NCBI chr 1:198,287,489...198,298,076
Ensembl chr 1:198,287,490...198,298,076
JBrowse link
G Ins2 insulin 2 decreases expression ISO Tacrolimus results in decreased expression of INS protein CTD PMID:17391142 NCBI chr 1:215,856,967...215,858,034
Ensembl chr 1:215,856,971...215,858,034
JBrowse link
G Irak1 interleukin-1 receptor-associated kinase 1 increases phosphorylation ISO Tacrolimus results in increased phosphorylation of IRAK1 protein CTD PMID:23958496 NCBI chr  X:156,716,469...156,726,367
Ensembl chr  X:156,716,604...156,725,977
JBrowse link
G Itgal integrin subunit alpha L decreases expression EXP Tacrolimus results in decreased expression of ITGAL CTD PMID:9794552 NCBI chr 1:198,744,053...198,781,745
Ensembl chr 1:198,744,050...198,781,750
JBrowse link
G Jak2 Janus kinase 2 increases phosphorylation ISO Tacrolimus results in increased phosphorylation of JAK2 protein CTD PMID:23958496 NCBI chr 1:247,398,667...247,457,521
Ensembl chr 1:247,398,598...247,458,509
JBrowse link
G Jun Jun proto-oncogene, AP-1 transcription factor subunit decreases expression EXP Tacrolimus results in decreased expression of JUN protein CTD PMID:9674596 NCBI chr 5:114,011,184...114,014,277
Ensembl chr 5:114,011,189...114,014,277
JBrowse link
G Junb JunB proto-oncogene, AP-1 transcription factor subunit increases expression ISO Tacrolimus results in increased expression of JUNB mRNA CTD PMID:23958496 NCBI chr19:26,092,972...26,094,756
Ensembl chr19:26,092,974...26,094,756
JBrowse link
G Kifap3 kinesin-associated protein 3 decreases expression EXP Tacrolimus results in decreased expression of KIFAP3 mRNA CTD PMID:21865292 NCBI chr13:82,072,497...82,217,256
Ensembl chr13:82,072,497...82,217,252
JBrowse link
G Kifc1 kinesin family member C1 decreases expression EXP Tacrolimus results in decreased expression of KIFC1 mRNA CTD PMID:21865292 NCBI chr20:5,509,059...5,526,175
Ensembl chr20:5,509,059...5,526,175
JBrowse link
G Klf5 Kruppel-like factor 5 increases expression EXP Tacrolimus results in increased expression of KLF5 mRNA CTD PMID:21865292 NCBI chr15:83,703,796...83,722,921
Ensembl chr15:83,703,791...83,722,921
JBrowse link
G Klf6 Kruppel-like factor 6 increases expression EXP Tacrolimus results in increased expression of KLF6 mRNA CTD PMID:21865292 NCBI chr17:67,887,939...67,945,052
Ensembl chr17:67,887,939...67,945,037
JBrowse link
G Klk1c10 kallikrein 1-related peptidase C10 increases expression EXP Tacrolimus results in increased expression of KLK1C10 mRNA CTD PMID:21865292 NCBI chr 1:99,890,294...99,894,353
Ensembl chr 1:99,890,294...99,894,353
JBrowse link
G Klk1c9 kallikrein 1-related peptidase C9 increases expression EXP Tacrolimus results in increased expression of KLK1C9 mRNA CTD PMID:21865292 NCBI chr 1:100,086,520...100,090,406
Ensembl chr 1:100,059,967...100,203,329
JBrowse link
G Kras KRAS proto-oncogene, GTPase increases expression ISO Tacrolimus results in increased expression of KRAS mRNA CTD PMID:25270620 NCBI chr 4:179,482,562...179,515,483
Ensembl chr 4:179,486,105...179,515,558
JBrowse link
G Krt20 keratin 20 increases expression ISO Tacrolimus results in increased expression of KRT20 mRNA CTD PMID:29362864 NCBI chr10:87,342,514...87,351,045
Ensembl chr10:87,342,619...87,351,045
JBrowse link
G Lamc2 laminin subunit gamma 2 increases expression EXP Tacrolimus results in increased expression of LAMC2 mRNA CTD PMID:21865292 NCBI chr13:70,566,643...70,632,126
Ensembl chr13:70,566,643...70,626,252
JBrowse link
G Lbp lipopolysaccharide binding protein increases expression EXP Tacrolimus results in increased expression of LBP mRNA CTD PMID:21865292 NCBI chr 3:154,786,232...154,812,910
Ensembl chr 3:154,786,215...154,813,464
JBrowse link
G Lcn2 lipocalin 2 increases expression EXP
ISO
Tacrolimus results in increased expression of LCN2 mRNA CTD PMID:21865292, PMID:29362864 NCBI chr 3:11,414,189...11,417,534
Ensembl chr 3:11,414,186...11,417,546
JBrowse link
G Lias lipoic acid synthetase decreases expression ISO Tacrolimus results in decreased expression of LIAS mRNA CTD PMID:21621594 NCBI chr14:44,507,217...44,524,287
Ensembl chr14:44,507,218...44,524,252
JBrowse link
G Lif LIF, interleukin 6 family cytokine increases expression ISO Tacrolimus results in increased expression of LIF mRNA CTD PMID:23958496 NCBI chr14:84,482,652...84,500,574
Ensembl chr14:84,482,674...84,500,642
JBrowse link
G Limk1 LIM domain kinase 1 increases expression ISO Tacrolimus results in increased expression of LIMK1 mRNA CTD PMID:29380240 NCBI chr12:25,036,630...25,070,538
Ensembl chr12:25,036,605...25,070,539
JBrowse link
G Llgl1 LLGL scribble cell polarity complex component 1 increases expression ISO Tacrolimus results in increased expression of LLGL1 mRNA CTD PMID:29380240 NCBI chr10:46,940,873...46,955,524
Ensembl chr10:46,940,965...46,954,674
JBrowse link
G LOC103692166 WD repeat-containing protein 54 decreases expression ISO Tacrolimus results in decreased expression of WDR54 mRNA CTD PMID:25270620 NCBI chr 4:113,984,754...113,988,487
Ensembl chr 4:114,850,815...114,853,868
Ensembl chr 4:114,850,815...114,853,868
JBrowse link
G Lta lymphotoxin alpha multiple interactions ISO Tacrolimus inhibits the reaction [enterotoxin A, Staphylococcal results in increased expression of LTA protein] CTD PMID:1371491 NCBI chr20:4,851,889...4,854,677
Ensembl chr20:4,852,496...4,854,677
JBrowse link
G Ltf lactotransferrin increases expression ISO Tacrolimus results in increased expression of LTF mRNA CTD PMID:21621594 NCBI chr 8:119,290,416...119,313,261
Ensembl chr 8:119,290,416...119,313,261
JBrowse link
G Ly86 lymphocyte antigen 86 increases expression ISO Tacrolimus results in increased expression of LY86 mRNA CTD PMID:29362864 NCBI chr17:28,104,535...28,191,447
Ensembl chr17:28,104,589...28,191,436
JBrowse link
G Lyve1 lymphatic vessel endothelial hyaluronan receptor 1 decreases expression ISO Tacrolimus results in decreased expression of LYVE1 mRNA CTD PMID:25270620 NCBI chr 1:175,663,266...175,676,699
Ensembl chr 1:175,663,266...175,676,699
JBrowse link
G Maff MAF bZIP transcription factor F increases expression ISO Tacrolimus results in increased expression of MAFF mRNA CTD PMID:23958496 NCBI chr 7:120,580,743...120,592,095
Ensembl chr 7:120,580,743...120,592,095
JBrowse link
G Mafk MAF bZIP transcription factor K increases expression ISO Tacrolimus results in increased expression of MAFK mRNA CTD PMID:23958496 NCBI chr12:16,923,989...16,934,706
Ensembl chr12:16,923,990...16,934,706
JBrowse link
G Manf mesencephalic astrocyte-derived neurotrophic factor increases expression ISO Tacrolimus results in increased expression of MANF mRNA CTD PMID:25270620 NCBI chr 8:115,623,175...115,626,408
Ensembl chr 8:115,623,178...115,626,380
JBrowse link
G Map3k7 mitogen activated protein kinase kinase kinase 7 increases phosphorylation ISO Tacrolimus results in increased phosphorylation of MAP3K7 protein CTD PMID:23958496 NCBI chr 5:47,183,142...47,244,424
Ensembl chr 5:47,186,558...47,244,416
JBrowse link
G Mapk8 mitogen-activated protein kinase 8 decreases activity
multiple interactions
EXP Tacrolimus results in decreased activity of MAPK8 protein
Tacrolimus inhibits the reaction [Oxygen deficiency results in increased activity of MAPK8 protein]
CTD PMID:12892836 NCBI chr16:9,620,854...9,709,342
Ensembl chr16:9,625,177...9,709,347
JBrowse link
G Mbnl2 muscleblind-like splicing regulator 2 decreases expression ISO Tacrolimus results in decreased expression of MBNL2 mRNA CTD PMID:25270620 NCBI chr15:105,640,097...105,797,933
Ensembl chr15:105,640,097...105,797,932
JBrowse link
G Mcam melanoma cell adhesion molecule decreases expression ISO Tacrolimus results in decreased expression of MCAM mRNA CTD PMID:25270620 NCBI chr 8:48,472,824...48,481,005
Ensembl chr 8:48,472,824...48,481,001
JBrowse link
G Mcrs1 microspherule protein 1 decreases expression ISO Tacrolimus results in decreased expression of MCRS1 mRNA CTD PMID:25270620 NCBI chr 7:140,910,420...140,919,234
Ensembl chr 7:140,910,423...140,919,234
JBrowse link
G Memo1 mediator of cell motility 1 decreases expression ISO Tacrolimus results in decreased expression of MEMO1 mRNA CTD PMID:25270620 NCBI chr 6:22,362,483...22,409,583
Ensembl chr 6:22,362,484...22,409,579
JBrowse link
G Mettl1 methyltransferase like 1 increases expression ISO Tacrolimus results in increased expression of METTL1 mRNA CTD PMID:25270620 NCBI chr 7:70,328,470...70,333,045
Ensembl chr 7:70,328,391...70,333,166
JBrowse link
G Mfsd1 major facilitator superfamily domain containing 1 increases expression ISO Tacrolimus results in increased expression of MFSD1 mRNA CTD PMID:25270620 NCBI chr 2:164,747,655...164,767,682
Ensembl chr 2:164,747,677...164,767,682
JBrowse link
G Mgll monoglyceride lipase decreases expression ISO Tacrolimus results in decreased expression of MGLL mRNA CTD PMID:25270620 NCBI chr 4:120,671,436...120,773,458
Ensembl chr 4:120,671,489...120,771,088
JBrowse link
G Mir146a microRNA 146a increases expression ISO Tacrolimus results in increased expression of MIR146 mRNA CTD PMID:29362864 NCBI chr10:28,962,476...28,962,570
Ensembl chr10:28,962,476...28,962,570
JBrowse link
G Mir146b microRNA 146b increases expression ISO Tacrolimus results in increased expression of MIR146B mRNA CTD PMID:29362864 NCBI chr 1:266,089,488...266,089,575
Ensembl chr 1:266,089,488...266,089,575
JBrowse link
G Mir193a microRNA 193a decreases expression ISO Tacrolimus results in decreased expression of MIR193A mRNA CTD PMID:29362864 NCBI chr10:67,065,885...67,065,996
Ensembl chr10:67,065,885...67,065,996
JBrowse link
G Mir200b microRNA 200b decreases expression ISO Tacrolimus results in decreased expression of MIR200B mRNA CTD PMID:29362864 NCBI chr 5:173,490,144...173,490,238
Ensembl chr 5:173,490,144...173,490,238
JBrowse link
G Mir21 microRNA 21 increases expression ISO Tacrolimus results in increased expression of MIR21A mRNA CTD PMID:29362864 NCBI chr10:73,902,210...73,902,301
Ensembl chr10:73,902,210...73,902,301
JBrowse link
G Mir34b microRNA 34b increases expression ISO Tacrolimus results in increased expression of MIR34B mRNA CTD PMID:29362864 NCBI chr 8:55,492,542...55,492,625
Ensembl chr 8:55,492,542...55,492,625
JBrowse link
G Mir551b microRNA 551b decreases expression ISO Tacrolimus results in decreased expression of MIR551B mRNA CTD PMID:29362864 NCBI chr 2:116,867,647...116,867,744
Ensembl chr 2:116,867,647...116,867,744
JBrowse link
G Mob4 MOB family member 4, phocein increases expression ISO Tacrolimus results in increased expression of MOB4 mRNA CTD PMID:25270620 NCBI chr 9:61,720,583...61,744,532
Ensembl chr 9:61,720,583...61,744,531
JBrowse link
G Mpo myeloperoxidase multiple interactions
decreases expression
EXP Tacrolimus inhibits the reaction [Indomethacin results in increased activity of MPO protein]
Tacrolimus results in decreased expression of MPO protein
CTD PMID:9655420, PMID:17202747 NCBI chr10:75,087,892...75,098,260
Ensembl chr10:75,087,892...75,098,260
JBrowse link
G Mrm3 mitochondrial rRNA methyltransferase 3 decreases expression ISO Tacrolimus results in decreased expression of MRM3 mRNA CTD PMID:25270620 NCBI chr10:64,398,308...64,406,193
Ensembl chr10:64,398,339...64,405,017
JBrowse link
G Ms4a6e membrane spanning 4-domains A6E increases expression ISO Tacrolimus results in increased expression of MS4A6C mRNA CTD PMID:29362864 NCBI chr 1:227,757,444...227,769,336
Ensembl chr 1:227,757,425...227,818,305
Ensembl chr 1:227,757,425...227,818,305
JBrowse link
G Msln mesothelin increases expression ISO Tacrolimus results in increased expression of MSLN mRNA CTD PMID:29362864 NCBI chr10:15,119,700...15,129,129
Ensembl chr10:15,119,663...15,125,408
JBrowse link
G Myc MYC proto-oncogene, bHLH transcription factor increases expression EXP
ISO
Tacrolimus results in increased expression of MYC mRNA CTD PMID:21865292, PMID:23958496 NCBI chr 7:102,586,313...102,591,240
Ensembl chr 7:102,586,313...102,591,240
JBrowse link
G Naaa N-acylethanolamine acid amidase increases expression ISO Tacrolimus results in increased expression of NAAA mRNA CTD PMID:29362864 NCBI chr14:17,283,262...17,302,364
Ensembl chr14:17,283,124...17,302,366
JBrowse link
G Nckap1l NCK associated protein 1 like increases expression ISO Tacrolimus results in increased expression of NCKAP1L mRNA CTD PMID:29362864 NCBI chr 7:145,068,239...145,113,507
Ensembl chr 7:145,068,286...145,113,507
JBrowse link
G Ncr3 natural cytotoxicity triggering receptor 3 increases expression ISO Tacrolimus results in increased expression of NCR3 CTD PMID:20736080 NCBI chr20:5,170,169...5,175,773
Ensembl chr20:5,170,215...5,175,773
JBrowse link
G Ndrg1 N-myc downstream regulated 1 increases expression ISO Tacrolimus results in increased expression of NDRG1 mRNA CTD PMID:25270620 NCBI chr 7:107,734,326...107,775,701
Ensembl chr 7:107,734,323...107,775,714
JBrowse link
G Nfatc3 nuclear factor of activated T-cells 3 multiple interactions ISO Tacrolimus inhibits the reaction [bisphenol A promotes the reaction [NFATC3 protein binds to IL4 promoter]]; Tacrolimus inhibits the reaction [nonylphenol promotes the reaction [NFATC3 protein binds to IL4 promoter]]; Tacrolimus inhibits the reaction [Thapsigargin affects the localization of and results in increased activity of NFATC3 protein] CTD PMID:10339586, PMID:12709020 NCBI chr19:38,039,542...38,114,003
Ensembl chr19:38,039,564...38,114,003
JBrowse link
G Nfatc4 nuclear factor of activated T-cells 4 multiple interactions ISO
EXP
Tacrolimus inhibits the reaction [20-hydroxy-5,8,11,14-eicosatetraenoic acid results in increased localization of NFATC4 protein]; Tacrolimus inhibits the reaction [Phenylephrine results in increased localization of NFATC4 protein] CTD PMID:16055480 NCBI chr15:34,493,163...34,502,238
Ensembl chr15:34,493,138...34,504,326
JBrowse link
G Nfe2l2 nuclear factor, erythroid 2-like 2 increases expression ISO Tacrolimus results in increased expression of NFE2L2 protein CTD PMID:23958496 NCBI chr 3:62,497,568...62,525,146
Ensembl chr 3:62,497,571...62,524,996
JBrowse link
G Nfkb1 nuclear factor kappa B subunit 1 multiple interactions
increases expression
ISO Tacrolimus inhibits the reaction [Tetrachlorodibenzodioxin affects the localization of NFKB1 protein]
Tacrolimus results in increased expression of NFKB1 mRNA
CTD PMID:18172213, PMID:18172886, PMID:23958496 NCBI chr 2:240,773,520...240,890,053
Ensembl chr 2:240,773,456...240,866,689
JBrowse link
G Nfkb2 nuclear factor kappa B subunit 2 increases expression ISO Tacrolimus results in increased expression of NFKB2 mRNA CTD PMID:23958496 NCBI chr 1:266,050,634...266,059,277
Ensembl chr 1:266,053,002...266,059,256
JBrowse link
G Nfkbia NFKB inhibitor alpha decreases degradation
increases phosphorylation
multiple interactions
ISO Tacrolimus results in decreased degradation of NFKBIA protein
Tacrolimus results in increased phosphorylation of NFKBIA protein
ethyl 6-(N-(2-chloro-4-fluorophenyl)sulfamoyl)cyclohex-1-ene-1-carboxylate inhibits the reaction [Tacrolimus results in increased phosphorylation of NFKBIA protein]
CTD PMID:16181452, PMID:23958496 NCBI chr 6:76,267,227...76,270,457
Ensembl chr 6:76,267,228...76,270,457
JBrowse link
G Nfkbib NFKB inhibitor beta multiple interactions ISO Tacrolimus inhibits the reaction [Tetrachlorodibenzodioxin results in decreased expression of NFKBIB protein] CTD PMID:18172213, PMID:18172886 NCBI chr 1:86,941,073...86,948,845
Ensembl chr 1:86,941,074...86,948,845
JBrowse link
G Nfkbie NFKB inhibitor epsilon increases expression ISO Tacrolimus results in increased expression of NFKBIE mRNA CTD PMID:23958496 NCBI chr 9:17,828,405...17,835,240
Ensembl chr 9:17,828,408...17,835,240
JBrowse link
G Ngf nerve growth factor multiple interactions EXP NGF protein inhibits the reaction [Tacrolimus results in increased activity of CASP3 protein]; Tacrolimus inhibits the reaction [NGF protein results in increased expression of SERPINE1 mRNA]; Tacrolimus inhibits the reaction [NGF protein results in increased expression of SERPINE1 protein] CTD PMID:17385075, PMID:23825664 NCBI chr 2:204,886,158...204,939,523
Ensembl chr 2:204,886,202...204,940,453
JBrowse link
G Nol8 nucleolar protein 8 increases expression ISO Tacrolimus results in increased expression of NOL8 mRNA CTD PMID:25270620 NCBI chr17:14,565,794...14,589,154
Ensembl chr17:14,565,794...14,589,154
Ensembl chr17:14,565,794...14,589,154
JBrowse link
G Nos1 nitric oxide synthase 1 multiple interactions EXP Tacrolimus inhibits the reaction [[Lithium co-treated with Pilocarpine] results in increased expression of NOS1 protein] CTD PMID:20149694 NCBI chr12:44,214,949...44,405,530
Ensembl chr12:44,213,943...44,520,341
JBrowse link
G Nos2 nitric oxide synthase 2 multiple interactions ISO
EXP
Tacrolimus inhibits the reaction [[Lipopolysaccharides results in increased expression of NOS2 protein] which results in increased chemical synthesis of Nitric Oxide]
Tacrolimus inhibits the reaction [[Lithium co-treated with Pilocarpine] results in increased expression of NOS2 protein]; Tacrolimus inhibits the reaction [Indomethacin results in increased expression of NOS2 mRNA]
CTD PMID:12144947, PMID:17202747, PMID:20149694 NCBI chr10:66,188,290...66,221,621
Ensembl chr10:66,189,786...66,313,190
JBrowse link
G Nos3 nitric oxide synthase 3 increases expression
decreases expression
decreases activity
ISO
EXP
Tacrolimus results in increased expression of NOS3 mRNA
Tacrolimus results in decreased expression of NOS3 mRNA
Tacrolimus results in decreased activity of NOS3 protein
CTD PMID:9931093, PMID:12352326 NCBI chr 4:7,321,908...7,342,404
Ensembl chr 4:7,320,668...7,342,410
JBrowse link
G Nox1 NADPH oxidase 1 increases expression EXP Tacrolimus results in increased expression of NOX1 mRNA CTD PMID:17085464 NCBI chr  X:104,909,328...104,932,508
Ensembl chr  X:104,909,326...104,932,508
JBrowse link
G Nppa natriuretic peptide A multiple interactions ISO Tacrolimus inhibits the reaction [NPR1 protein affects the expression of NPPA mRNA] CTD PMID:15939815 NCBI chr 5:164,808,407...164,809,716
Ensembl chr 5:164,808,323...164,809,705
JBrowse link
G Nppb natriuretic peptide B multiple interactions ISO Tacrolimus inhibits the reaction [NPR1 protein affects the expression of NPPB mRNA] CTD PMID:15939815 NCBI chr 5:164,796,176...164,797,538
Ensembl chr 5:164,796,185...164,797,531
JBrowse link
G Npr1 natriuretic peptide receptor 1 multiple interactions ISO Tacrolimus inhibits the reaction [NPR1 protein affects the expression of FN1 mRNA]; Tacrolimus inhibits the reaction [NPR1 protein affects the expression of NPPA mRNA]; Tacrolimus inhibits the reaction [NPR1 protein affects the expression of NPPB mRNA] CTD PMID:15939815 NCBI chr 2:189,840,403...189,857,032
Ensembl chr 2:189,840,403...189,856,090
JBrowse link
G Nr3c1 nuclear receptor subfamily 3, group C, member 1 multiple interactions
increases activity
ISO Tacrolimus inhibits the reaction [NR3C1 protein binds to FKBP5 protein]; Tacrolimus promotes the reaction [Dexamethasone binds to NR3C1 protein]; Tacrolimus promotes the reaction [NR3C1 protein binds to PPP5C protein]
Tacrolimus results in increased activity of NR3C1 protein
CTD PMID:15697228 NCBI chr18:31,728,373...32,704,022
Ensembl chr18:31,728,373...31,749,647
JBrowse link
G Ogn osteoglycin increases expression EXP
ISO
Tacrolimus results in increased expression of OGN mRNA CTD PMID:21865292, PMID:29362864 NCBI chr17:14,607,442...14,628,274
Ensembl chr17:15,447,716...15,467,359
Ensembl chr17:15,447,716...15,467,359
JBrowse link
G Olfml3 olfactomedin-like 3 increases expression ISO Tacrolimus results in increased expression of OLFML3 mRNA CTD PMID:29362864 NCBI chr 2:206,219,419...206,222,248
Ensembl chr 2:206,219,419...206,222,248
JBrowse link
G Panx1 Pannexin 1 increases expression ISO Tacrolimus results in increased expression of PANX1 mRNA CTD PMID:29362864 NCBI chr 8:13,567,185...13,606,040
Ensembl chr 8:13,566,739...13,606,040
JBrowse link
G Pbk PDZ binding kinase increases expression ISO Tacrolimus results in increased expression of PBK mRNA CTD PMID:29362864 NCBI chr15:42,489,253...42,500,377
Ensembl chr15:42,489,377...42,500,395
JBrowse link
G Pcbp4 poly(rC) binding protein 4 decreases expression ISO Tacrolimus results in decreased expression of PCBP4 mRNA CTD PMID:25270620 NCBI chr 8:115,154,848...115,165,706
Ensembl chr 8:115,155,470...115,165,706
JBrowse link
G Pcna proliferating cell nuclear antigen multiple interactions ISO Tacrolimus affects the reaction [[9,10-Dimethyl-1,2-benzanthracene co-treated with Tetradecanoylphorbol Acetate] affects the expression of PCNA protein]; Tacrolimus affects the reaction [Tacrolimus affects the reaction [[9,10-Dimethyl-1,2-benzanthracene co-treated with Tetradecanoylphorbol Acetate] affects the expression of PCNA protein]] CTD PMID:25770929 NCBI chr 3:124,880,698...124,884,570
Ensembl chr 3:124,880,698...124,884,570
JBrowse link
G Pcolce procollagen C-endopeptidase enhancer decreases expression ISO Tacrolimus results in decreased expression of PCOLCE mRNA CTD PMID:25270620 NCBI chr12:22,153,995...22,160,311
Ensembl chr12:22,153,983...22,160,337
JBrowse link
G Pdcd2 programmed cell death 2 increases expression ISO Tacrolimus results in increased expression of PDCD2 mRNA CTD PMID:25270620 NCBI chr 1:57,512,968...57,518,458
Ensembl chr 1:57,512,968...57,518,458
JBrowse link
G Pdgfra platelet derived growth factor receptor alpha increases expression ISO Tacrolimus results in increased expression of PDGFRA mRNA CTD PMID:29362864 NCBI chr14:35,527,926...35,581,130
Ensembl chr14:35,527,927...35,581,031
JBrowse link
G Pdia4 protein disulfide isomerase family A, member 4 increases expression ISO Tacrolimus results in increased expression of PDIA4 mRNA CTD PMID:25270620 NCBI chr 4:77,470,636...77,489,535
Ensembl chr 4:77,470,636...77,489,535
JBrowse link
G Pdia6 protein disulfide isomerase family A, member 6 increases expression ISO Tacrolimus results in increased expression of PDIA6 mRNA CTD PMID:25270620 NCBI chr 6:42,568,269...42,585,654
Ensembl chr 6:42,568,220...42,585,652
JBrowse link
G Phlda1 pleckstrin homology-like domain, family A, member 1 increases expression ISO Tacrolimus results in increased expression of PHLDA1 mRNA CTD PMID:23958496 NCBI chr 7:54,247,460...54,249,664
Ensembl chr 7:54,247,460...54,249,664
JBrowse link
G Pid1 phosphotyrosine interaction domain containing 1 increases expression ISO Tacrolimus results in increased expression of PID1 mRNA CTD PMID:29362864 NCBI chr 9:91,667,748...91,683,468
Ensembl chr 9:91,665,986...91,882,927
JBrowse link
G Pink1 PTEN induced kinase 1 multiple interactions ISO PINK1 protein affects the reaction [Tacrolimus results in increased phosphorylation of DNM1L protein] CTD PMID:19492085 NCBI chr 5:156,677,146...156,689,258
Ensembl chr 5:156,677,146...156,689,415
JBrowse link
G Pkmyt1 protein kinase, membrane associated tyrosine/threonine 1 increases expression ISO Tacrolimus results in increased expression of PKMYT1 mRNA CTD PMID:29362864 NCBI chr10:13,061,077...13,072,277
Ensembl chr10:13,061,170...13,073,283
JBrowse link
G Pkp4 plakophilin 4 decreases expression EXP Tacrolimus results in decreased expression of PKP4 mRNA CTD PMID:21865292 NCBI chr 3:45,211,097...45,414,524
Ensembl chr 3:45,277,348...45,414,613
JBrowse link
G Pla2g12a phospholipase A2, group XIIA increases expression ISO Tacrolimus results in increased expression of PLA2G12A mRNA CTD PMID:25270620 NCBI chr 2:235,311,664...235,327,972
Ensembl chr 2:235,311,719...235,327,972
JBrowse link
G Plat plasminogen activator, tissue type decreases expression ISO Tacrolimus results in decreased expression of PLAT mRNA CTD PMID:25270620 NCBI chr16:74,098,263...74,122,897
Ensembl chr16:74,098,260...74,122,889
JBrowse link
G Plbd2 phospholipase B domain containing 2 decreases expression ISO Tacrolimus results in decreased expression of PLBD2 mRNA CTD PMID:25270620 NCBI chr12:41,600,005...41,619,779
Ensembl chr12:41,600,005...41,619,186
JBrowse link
G Por cytochrome p450 oxidoreductase affects response to substance ISO POR polymorphism affects the susceptibility to Tacrolimus CTD PMID:24113216 NCBI chr12:23,998,411...24,017,063
Ensembl chr12:23,998,411...24,046,814
JBrowse link
G Ppara peroxisome proliferator activated receptor alpha affects response to substance ISO PPARA polymorphism affects the susceptibility to Tacrolimus CTD PMID:24113216 NCBI chr 7:126,618,872...126,687,282
Ensembl chr 7:126,619,196...126,681,752
JBrowse link
G Pparg peroxisome proliferator-activated receptor gamma multiple interactions ISO [Sirolimus co-treated with Tacrolimus] results in increased expression of PPARG protein CTD PMID:17016853 NCBI chr 4:147,274,055...147,399,383
Ensembl chr 4:147,274,107...147,399,380
JBrowse link
G Ppl periplakin increases expression EXP Tacrolimus results in increased expression of PPL mRNA CTD PMID:21865292 NCBI chr10:10,644,572...10,690,223
Ensembl chr10:10,644,572...10,690,223
JBrowse link
G Ppp1r15a protein phosphatase 1, regulatory subunit 15A increases expression ISO Tacrolimus results in increased expression of PPP1R15A mRNA CTD PMID:23958496 NCBI chr 1:101,511,899...101,515,043
Ensembl chr 1:101,511,901...101,514,974
JBrowse link
G Ppp3ca protein phosphatase 3 catalytic subunit alpha multiple interactions
decreases activity
ISO [Tacrolimus results in decreased activity of PPP3CA protein] which results in decreased susceptibility to Thapsigargin CTD PMID:10898953, PMID:19553475 NCBI chr 2:241,909,332...242,186,861
Ensembl chr 2:241,909,832...242,184,854
JBrowse link
G Ppp5c protein phosphatase 5, catalytic subunit multiple interactions ISO Tacrolimus promotes the reaction [NR3C1 protein binds to PPP5C protein] CTD PMID:15697228 NCBI chr 1:78,944,054...78,968,361
Ensembl chr 1:78,944,040...78,968,329
JBrowse link
G Prcp prolylcarboxypeptidase increases expression EXP Tacrolimus results in increased expression of PRCP mRNA CTD PMID:21865292 NCBI chr 1:157,701,089...157,750,177
Ensembl chr 1:157,701,089...157,750,169
JBrowse link
G Prlr prolactin receptor decreases expression EXP Tacrolimus results in decreased expression of PRLR mRNA CTD PMID:21865292 NCBI chr 2:60,131,410...60,325,686
Ensembl chr 2:60,131,776...60,325,692
JBrowse link
G Psmb10 proteasome 20S subunit beta 10 increases expression ISO Tacrolimus results in increased expression of PSMB10 mRNA CTD PMID:29362864 NCBI chr19:37,909,543...37,912,027
Ensembl chr19:37,909,546...37,912,027
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 multiple interactions
increases expression
ISO Tacrolimus inhibits the reaction [bisperoxovanadium results in increased expression of PTGS2 mRNA]
Tacrolimus results in increased expression of PTGS2 mRNA
CTD PMID:12493747, PMID:23958496 NCBI chr13:67,351,230...67,356,920
Ensembl chr13:67,351,087...67,359,335
JBrowse link
G Ptpn5 protein tyrosine phosphatase, non-receptor type 5 decreases activity ISO Tacrolimus results in decreased activity of PTPN5 protein CTD PMID:17360923 NCBI chr 1:103,197,918...103,258,309
Ensembl chr 1:103,197,915...103,256,823
JBrowse link
G Ptprz1 protein tyrosine phosphatase, receptor type Z1 increases expression EXP Tacrolimus results in increased expression of PTPRZ1 mRNA CTD PMID:21865292 NCBI chr 4:49,941,046...50,140,764
Ensembl chr 4:49,941,304...50,140,762
JBrowse link
G Rab4a RAB4A, member RAS oncogene family increases expression ISO Tacrolimus results in increased expression of RAB4A mRNA CTD PMID:29380240 NCBI chr19:56,585,598...56,613,078
Ensembl chr19:56,585,767...56,613,075
JBrowse link
G Rac1 Rac family small GTPase 1 increases expression EXP Tacrolimus results in increased expression of RAC1 mRNA CTD PMID:17085464 NCBI chr12:13,090,316...13,111,841
Ensembl chr12:13,090,172...13,111,873
JBrowse link
G Ramp1 receptor activity modifying protein 1 increases expression ISO Tacrolimus results in increased expression of RAMP1 mRNA CTD PMID:29362864 NCBI chr 9:98,313,632...98,364,206
Ensembl chr 9:98,313,632...98,364,205
JBrowse link
G Rcc1 regulator of chromosome condensation 1 decreases expression ISO Tacrolimus results in decreased expression of RCC1 mRNA CTD PMID:25270620 NCBI chr 5:150,508,840...150,531,062
Ensembl chr 5:150,509,040...150,525,254
JBrowse link
G Rcor2 REST corepressor 2 decreases expression ISO Tacrolimus results in decreased expression of RCOR2 mRNA CTD PMID:25270620 NCBI chr 1:222,513,970...222,525,356
Ensembl chr 1:222,519,615...222,524,779
JBrowse link
G Rel REL proto-oncogene, NF-kB subunit multiple interactions ISO Tacrolimus inhibits the reaction [Tetrachlorodibenzodioxin affects the localization of REL protein] CTD PMID:18172213 NCBI chr14:108,490,794...108,517,582
Ensembl chr14:108,491,069...108,509,892
JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit multiple interactions ISO [Tacrolimus co-treated with Thapsigargin] affects the localization of and results in increased activity of RELA protein; Tacrolimus affects the localization of and results in increased activity of RELA protein; Tacrolimus inhibits the reaction [Tetrachlorodibenzodioxin affects the localization of RELA protein]; Tacrolimus results in increased phosphorylation of and affects the localization of RELA protein CTD PMID:10339586, PMID:18172886, PMID:23958496 NCBI chr 1:220,992,770...221,003,249
Ensembl chr 1:220,992,770...221,003,249
JBrowse link
G Relb RELB proto-oncogene, NF-kB subunit increases expression ISO Tacrolimus results in increased expression of RELB mRNA CTD PMID:23958496 NCBI chr 1:80,517,081...80,545,019
Ensembl chr 1:80,517,411...80,544,825
JBrowse link
G Ren renin multiple interactions
increases expression
decreases activity
EXP nilvadipine inhibits the reaction [Tacrolimus results in increased expression of REN protein]
Tacrolimus results in increased expression of REN mRNA; Tacrolimus results in increased expression of REN protein
Tacrolimus results in decreased activity of REN protein
CTD PMID:7509514, PMID:7532090, PMID:7533848, PMID:12469222, PMID:21865292 NCBI chr13:50,502,724...50,513,953
Ensembl chr13:50,502,724...50,514,151
JBrowse link
G Renbp renin binding protein increases expression ISO Tacrolimus results in increased expression of RENBP mRNA CTD PMID:25270620 NCBI chr  X:156,854,490...156,863,548
Ensembl chr  X:156,854,594...156,863,528
JBrowse link
G Rgn regucalcin decreases expression EXP Tacrolimus results in decreased expression of RGN mRNA CTD PMID:21865292 NCBI chr  X:1,833,484...1,848,904
Ensembl chr  X:1,833,492...1,848,904
JBrowse link
G Rgs16 regulator of G-protein signaling 16 increases expression ISO Tacrolimus results in increased expression of RGS16 mRNA CTD PMID:29362864 NCBI chr13:71,163,411...71,185,147
Ensembl chr13:71,179,910...71,185,216
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G Rhebl1 RHEB like 1 increases expression ISO Tacrolimus results in increased expression of RHEBL1 mRNA CTD PMID:23958496 NCBI chr 7:140,552,704...140,556,980
Ensembl chr 7:140,552,733...140,556,639
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G Rhou ras homolog family member U increases expression ISO Tacrolimus results in increased expression of RHOU mRNA CTD PMID:29362864 NCBI chr19:56,431,787...56,443,896
Ensembl chr19:56,435,577...56,441,733
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G Rnase2 ribonuclease A family member 2 increases expression ISO Tacrolimus results in increased expression of RNASE2A mRNA CTD PMID:29362864 NCBI chr15:28,154,482...28,155,291
Ensembl chr15:28,154,482...28,155,291
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G Rnase3 ribonuclease A family member 3 increases expression ISO Tacrolimus results in increased expression of EAR1 mRNA CTD PMID:29362864 NCBI chr15:28,216,744...28,217,614
Ensembl chr15:28,216,744...28,217,614
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G Rpn1 ribophorin I increases expression ISO Tacrolimus results in increased expression of RPN1 mRNA CTD PMID:25270620 NCBI chr 4:119,997,232...120,018,687
Ensembl chr 4:119,997,268...120,018,679
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G Rps6 ribosomal protein S6 multiple interactions ISO Tacrolimus inhibits the reaction [Sirolimus inhibits the reaction [IL2 protein results in increased phosphorylation of RPS6 protein]] CTD PMID:1614535 NCBI chr 5:105,197,821...105,200,681
Ensembl chr 5:105,197,857...105,200,148
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G Rrp9 ribosomal RNA processing 9, U3 small nucleolar RNA binding protein decreases expression ISO Tacrolimus results in decreased expression of RRP9 mRNA CTD PMID:25270620 NCBI chr 8:115,179,899...115,188,551
Ensembl chr 8:115,179,893...115,188,588
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G Runx2 RUNX family transcription factor 2 decreases expression EXP Tacrolimus results in decreased expression of RUNX2 mRNA CTD PMID:15780950 NCBI chr 9:18,564,743...18,773,092
Ensembl chr 9:18,564,927...18,773,092
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G Ryr1 ryanodine receptor 1 multiple interactions ISO Tacrolimus inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of RYR1 protein] CTD PMID:18172213, PMID:18172886 NCBI chr 1:87,959,596...88,066,252
Ensembl chr 1:87,959,712...88,066,101
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G S100a6 S100 calcium binding protein A6 increases expression ISO Tacrolimus results in increased expression of S100A6 mRNA CTD PMID:29362864 NCBI chr 2:190,007,013...190,008,512
Ensembl chr 2:190,007,216...190,008,511
JBrowse link