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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:acenaphthoquinone
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Accession:CHEBI:15342 term browser browse the term
Definition:An orthoquinone that is the 1,2-dioxo derivative of acenaphthene.
Synonyms:exact_synonym: acenaphthylene-1,2-dione
 related_synonym: 1,2-Diketoacenaphthene;   1,2-acenaphthenedione;   1,2-acenaphthenequinone;   1,2-acenaphthylenedione;   AcQ;   Acenaphthenequinone;   Aq;   Formula=C12H6O2;   InChI=1S/C12H6O2/c13-11-8-5-1-3-7-4-2-6-9(10(7)8)12(11)14/h1-6H;   InChIKey=AFPRJLBZLPBTPZ-UHFFFAOYSA-N;   SMILES=O=c1c2cccc3cccc(c23)c1=O;   acenaphthene quinone;   acenaphthene-1,2-dione;   acenaphthodione;   acenaphthylene-1,2-quinone;   acenaphthylenedione;   diketoacenaphthene
 alt_id: CHEBI:13702;   CHEBI:22155;   CHEBI:2381;   CHEBI:40798
 xref: Beilstein:879172;   CAS:82-86-0;   Gmelin:143091;   KEGG:C02807
 xref_mesh: MESH:C023722
 xref: PDB:1OAX;   PDBeChem:ANQ;   PMID:14500876;   PMID:1650428;   PMID:17082565;   PMID:17925309;   PMID:21941409;   PMID:22010712;   PMID:22779655;   Reaxys:879172;   Wikipedia:Acenaphthoquinone



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acenaphthoquinone term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dhrs11 dehydrogenase/reductase 11 increases reduction ISO DHRS11 protein results in increased reduction of acenaphthenequinone CTD PMID:30926317 NCBI chr10:69,698,214...69,708,294
Ensembl chr10:69,698,214...69,708,295
JBrowse link
G Nfkb1 nuclear factor kappa B subunit 1 multiple interactions ISO acenaphthenequinone affects the localization of and results in increased expression of NFKB1 protein CTD PMID:17082565 NCBI chr 2:224,016,214...224,132,135
Ensembl chr 2:224,016,214...224,110,404
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 multiple interactions
increases expression
ISO [acenaphthenequinone results in increased chemical synthesis of Reactive Oxygen Species] which affects the expression of PTGS2 protein; Acetylcysteine inhibits the reaction [acenaphthenequinone results in increased expression of PTGS2 protein]; BAY 11-7085 inhibits the reaction [acenaphthenequinone results in increased expression of PTGS2 protein] CTD PMID:17082565 NCBI chr13:62,164,080...62,169,770
Ensembl chr13:62,163,932...62,172,188
JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit multiple interactions
increases expression
ISO 2,3,5-trimethyl-6-(12-hydroxy-5,10-dodecadiynyl)-1,4-benzoquinone inhibits the reaction [acenaphthenequinone results in increased expression of RELA protein]; acenaphthenequinone affects the localization of and results in increased expression of RELA protein; Acetylcysteine inhibits the reaction [acenaphthenequinone results in increased expression of RELA protein] CTD PMID:17082565 PMID:17925309 NCBI chr 1:202,925,001...202,935,484
Ensembl chr 1:202,924,945...202,935,484
JBrowse link

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  CHEBI ontology 20072
    role 20024
      biological role 20023
        epitope 7007
          acenaphthoquinone 4
Path 2
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  CHEBI ontology 20072
    subatomic particle 20071
      composite particle 20071
        hadron 20071
          baryon 20071
            nucleon 20071
              atomic nucleus 20071
                atom 20071
                  main group element atom 19971
                    p-block element atom 19971
                      carbon group element atom 19894
                        carbon atom 19887
                          organic molecular entity 19887
                            organic group 18965
                              organic divalent group 18951
                                organodiyl group 18951
                                  carbonyl group 18903
                                    carbonyl compound 18903
                                      ketone 17111
                                        cyclic ketone 15664
                                          quinone 8523
                                            orthoquinones 87
                                              acenaphthoquinone 4
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