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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:acenaphthoquinone
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Accession:CHEBI:15342 term browser browse the term
Definition:An orthoquinone that is the 1,2-dioxo derivative of acenaphthene.
Synonyms:exact_synonym: acenaphthylene-1,2-dione
 related_synonym: 1,2-Diketoacenaphthene;   1,2-acenaphthenedione;   1,2-acenaphthenequinone;   1,2-acenaphthylenedione;   AcQ;   Acenaphthenequinone;   Aq;   Formula=C12H6O2;   InChI=1S/C12H6O2/c13-11-8-5-1-3-7-4-2-6-9(10(7)8)12(11)14/h1-6H;   InChIKey=AFPRJLBZLPBTPZ-UHFFFAOYSA-N;   SMILES=O=c1c2cccc3cccc(c23)c1=O;   acenaphthene quinone;   acenaphthene-1,2-dione;   acenaphthodione;   acenaphthylene-1,2-quinone;   acenaphthylenedione;   diketoacenaphthene
 alt_id: CHEBI:13702;   CHEBI:22155;   CHEBI:2381;   CHEBI:40798
 xref: Beilstein:879172;   CAS:82-86-0;   Gmelin:143091;   KEGG:C02807
 xref_mesh: MESH:C023722
 xref: PDB:1OAX;   PDBeChem:ANQ;   PMID:14500876;   PMID:1650428;   PMID:17082565;   PMID:17925309;   PMID:21941409;   PMID:22010712;   PMID:22779655;   Reaxys:879172;   Wikipedia:Acenaphthoquinone


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acenaphthoquinone term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dhrs11 dehydrogenase/reductase 11 increases reduction ISO DHRS11 protein results in increased reduction of acenaphthenequinone CTD PMID:30926317 NCBI chr10:69,698,214...69,708,294 JBrowse link
G Nfkb1 nuclear factor kappa B subunit 1 multiple interactions ISO acenaphthenequinone affects the localization of and results in increased expression of NFKB1 protein CTD PMID:17082565 NCBI chr 2:224,016,214...224,132,135 JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 multiple interactions
increases expression
ISO [acenaphthenequinone results in increased chemical synthesis of Reactive Oxygen Species] which affects the expression of PTGS2 protein; Acetylcysteine inhibits the reaction [acenaphthenequinone results in increased expression of PTGS2 protein]; BAY 11-7085 inhibits the reaction [acenaphthenequinone results in increased expression of PTGS2 protein] CTD PMID:17082565 NCBI chr13:62,164,080...62,169,770 JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit multiple interactions
increases expression
ISO 2,3,5-trimethyl-6-(12-hydroxy-5,10-dodecadiynyl)-1,4-benzoquinone inhibits the reaction [acenaphthenequinone results in increased expression of RELA protein]; acenaphthenequinone affects the localization of and results in increased expression of RELA protein; Acetylcysteine inhibits the reaction [acenaphthenequinone results in increased expression of RELA protein] CTD PMID:17082565 PMID:17925309 NCBI chr 1:202,925,001...202,935,484 JBrowse link

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Path 1
Term Annotations click to browse term
  CHEBI ontology 19762
    role 19708
      biological role 19708
        epitope 6979
          acenaphthoquinone 4
Path 2
Term Annotations click to browse term
  CHEBI ontology 19762
    subatomic particle 19760
      composite particle 19760
        hadron 19760
          baryon 19760
            nucleon 19760
              atomic nucleus 19760
                atom 19760
                  main group element atom 19651
                    p-block element atom 19651
                      carbon group element atom 19570
                        carbon atom 19560
                          organic molecular entity 19560
                            organic group 18611
                              organic divalent group 18602
                                organodiyl group 18602
                                  carbonyl group 18519
                                    carbonyl compound 18519
                                      ketone 16858
                                        cyclic ketone 15234
                                          quinone 8378
                                            orthoquinones 87
                                              acenaphthoquinone 4
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