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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:sulfide(2-)
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Accession:CHEBI:15138 term browser browse the term
Definition:A divalent inorganic anion obtained by removal of both protons from hydrogen sulfide.
Synonyms:related_synonym: Formula=S;   InChI=1S/S/q-2;   InChIKey=UCKMPCXJQFINFW-UHFFFAOYSA-N;   S(2-);   SMILES=[S--];   Sulfanediide;   sulfide;   sulphide
 xref: CAS:18496-25-8;   UM-BBD_compID:c0569
 cyclic_relationship: is_conjugate_base_of CHEBI:29919


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sodium sulfide (anhydrous) term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cldn11 claudin 11 multiple interactions ISO [Hydrogen Sulfide results in increased abundance of sodium sulfide] which results in decreased expression of CLDN11 protein; Fatty Acids, Omega-3 inhibits the reaction [[Hydrogen Sulfide results in increased abundance of sodium sulfide] which results in decreased expression of CLDN11 protein] CTD PMID:33068716 NCBI chr 2:115,823,541...115,836,846
Ensembl chr 2:115,823,538...115,836,846
JBrowse link
G Cldn5 claudin 5 multiple interactions ISO [Hydrogen Sulfide results in increased abundance of sodium sulfide] which results in decreased expression of CLDN5 mRNA; [Hydrogen Sulfide results in increased abundance of sodium sulfide] which results in decreased expression of CLDN5 protein CTD PMID:33068716 NCBI chr11:86,356,292...86,357,718
Ensembl chr11:86,356,294...86,357,718
JBrowse link
G Ctnnb1 catenin beta 1 multiple interactions ISO [Hydrogen Sulfide results in increased abundance of sodium sulfide] which results in decreased expression of CTNNB1 mRNA; Fatty Acids, Omega-3 inhibits the reaction [[Hydrogen Sulfide results in increased abundance of sodium sulfide] which results in decreased expression of CTNNB1 mRNA] CTD PMID:33068716 NCBI chr 8:129,601,511...129,628,378
Ensembl chr 8:129,617,812...129,627,372
JBrowse link
G Gja1 gap junction protein, alpha 1 multiple interactions ISO [Hydrogen Sulfide results in increased abundance of sodium sulfide] which results in decreased expression of GJA1 mRNA; Fatty Acids, Omega-3 inhibits the reaction [[Hydrogen Sulfide results in increased abundance of sodium sulfide] which results in decreased expression of GJA1 mRNA] CTD PMID:33068716 NCBI chr20:37,876,650...37,889,097
Ensembl chr20:37,876,650...37,889,089
JBrowse link
G Idh2 isocitrate dehydrogenase (NADP(+)) 2 multiple interactions EXP [[sodium sulfide results in increased abundance of Hydrogen Sulfide] which co-treated with Paraquat] results in decreased expression of IDH2 protein; [sodium sulfide results in increased abundance of Hydrogen Sulfide] inhibits the reaction [Paraquat results in decreased expression of and results in decreased activity of IDH2 protein] CTD PMID:32064027 NCBI chr 1:141,874,354...141,893,674
Ensembl chr 1:141,866,283...141,893,705
JBrowse link
G Il6 interleukin 6 multiple interactions EXP sodium sulfide inhibits the reaction [cobaltous chloride results in increased secretion of IL6 protein] CTD PMID:23624824 NCBI chr 4:3,043,231...3,047,807
Ensembl chr 4:3,043,231...3,047,807
JBrowse link
G Nfe2l2 nuclear factor, erythroid 2-like 2 multiple interactions EXP NFE2L2 protein affects the reaction [[sodium sulfide results in increased abundance of Hydrogen Sulfide] inhibits the reaction [Paraquat results in decreased expression of SIRT3 protein]] CTD PMID:32064027 NCBI chr 3:62,497,568...62,525,146
Ensembl chr 3:62,497,571...62,524,996
JBrowse link
G Ocln occludin multiple interactions ISO [Hydrogen Sulfide results in increased abundance of sodium sulfide] which results in decreased expression of OCLN protein; Fatty Acids, Omega-3 inhibits the reaction [[Hydrogen Sulfide results in increased abundance of sodium sulfide] which results in decreased expression of OCLN protein] CTD PMID:33068716 NCBI chr 2:30,527,327...30,577,218
Ensembl chr 2:30,527,715...30,577,218
JBrowse link
G Sirt3 sirtuin 3 multiple interactions EXP [sodium sulfide results in increased abundance of Hydrogen Sulfide] inhibits the reaction [Paraquat results in decreased expression of SIRT3 protein]; NFE2L2 protein affects the reaction [[sodium sulfide results in increased abundance of Hydrogen Sulfide] inhibits the reaction [Paraquat results in decreased expression of SIRT3 protein]] CTD PMID:32064027 NCBI chr 1:213,613,502...213,636,061
Ensembl chr 1:213,613,513...213,635,546
JBrowse link
G Sod1 superoxide dismutase 1 increases metabolic processing ISO sodium sulfide results in increased metabolism of SOD1 protein CTD PMID:15096637 NCBI chr11:30,363,282...30,368,858
Ensembl chr11:30,363,280...30,368,862
JBrowse link
G Tjp1 tight junction protein 1 multiple interactions ISO 4-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole inhibits the reaction [[Hydrogen Sulfide results in increased abundance of sodium sulfide] which results in decreased expression of TJP1 protein]; [Hydrogen Sulfide results in increased abundance of sodium sulfide] which results in decreased expression of TJP1 mRNA; [Hydrogen Sulfide results in increased abundance of sodium sulfide] which results in decreased expression of TJP1 protein; Fatty Acids, Omega-3 inhibits the reaction [[Hydrogen Sulfide results in increased abundance of sodium sulfide] which results in decreased expression of TJP1 mRNA]; Fatty Acids, Omega-3 inhibits the reaction [[Hydrogen Sulfide results in increased abundance of sodium sulfide] which results in decreased expression of TJP1 protein] CTD PMID:33068716 NCBI chr 1:126,146,489...126,515,359
Ensembl chr 1:126,146,489...126,227,469
JBrowse link
G Vcl vinculin multiple interactions ISO [Hydrogen Sulfide results in increased abundance of sodium sulfide] which results in decreased expression of VCL mRNA; Fatty Acids, Omega-3 inhibits the reaction [[Hydrogen Sulfide results in increased abundance of sodium sulfide] which results in decreased expression of VCL mRNA] CTD PMID:33068716 NCBI chr15:3,455,211...3,544,738
Ensembl chr15:3,455,211...3,544,702
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19775
    chemical entity 19775
      molecular entity 19774
        ion 15946
          anion 14970
            inorganic anion 11948
              divalent inorganic anion 5779
                sulfide(2-) 12
                  sulfide salt + 12
paths to the root